CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Dithiopyr
Accession: CHEBI:81987
browse the term
Definition: A thioester that has formula C15H16F5NO2S2.
Synonyms: related_synonym: Formula=C15H16F5NO2S2; InChI=1S/C15H16F5NO2S2/c1-6(2)5-7-8(13(22)24-3)10(12(16)17)21-11(15(18,19)20)9(7)14(23)25-4/h6,12H,5H2,1-4H3; InChIKey=YUBJPYNSGLJZPQ-UHFFFAOYSA-N; SMILES=CSC(=O)c1c(nc(c(C(=O)SC)c1CC(C)C)C(F)(F)F)C(F)F
xref: CAS:97886-45-8; KEGG:C18826
xref_mesh: MESH:C071869
xref: PPDB:259
G
Ar
androgen receptor
multiple interactions
ISO
dithiopyr inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
CTD
PMID:33049310
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
ISO
dithiopyr results in increased expression of CYP3A4 mRNA
CTD
PMID:17293382
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Esr1
estrogen receptor 1
multiple interactions
ISO
dithiopyr binds to and results in increased activity of ESR1 protein
CTD
PMID:33049310
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
dithiopyr binds to and results in increased activity of NR1I2 protein
CTD
PMID:33049310
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
dithiopyr binds to and results in increased activity of PPARG protein
CTD
PMID:33049310
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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