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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:spirotetramat
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Accession:CHEBI:81975 term browser browse the term
Definition:An azaspiro compound that is methoxycyclohexane which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 3 and 4 by 2,5-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively (the cis isomer). It is a proinsecticide (via hydrolysis of the ethyl carbonate group to give the corresponding 4-hydroxypyrrol-2-one, 'spirotetramat-enol') and is used for the control of a wide range of sucking insects on fruit and potato crops.
Synonyms:exact_synonym: (5s,8s)-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate
 related_synonym: Formula=C21H27NO5;   InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)/t15-,21+;   InChIKey=CLSVJBIHYWPGQY-GGYDESQDSA-N;   Movento;   SMILES=C1(=C(C=CC(=C1)C)C)C=2C(NC3(C2OC(OCC)=O)CCC(CC3)OC)=O;   Ultor;   cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate;   cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethylcarbonate;   ethyl cis-8-methoxy-2-oxo-3-(2,5-xylyl)-1-azaspiro[4.5]dec-3-en-4-yl carbonate
 xref: CAS:203313-25-1;   KEGG:C18807
 xref_mesh: MESH:C570705
 xref: PMID:22160136;   PMID:22531003;   PMID:22872376;   PMID:24772560;   PMID:24835551;   PMID:25281882;   PMID:26081578;   PMID:26304426;   PMID:26383737;   PMID:26449612;   PMID:26743711;   PMID:26898726;   PMID:27083908;   PMID:27788413;   PMID:27857899;   PMID:27917277;   PMID:27989834;   PMID:28139069;   PMID:28334236;   PPDB:1119;   Patent:EP2039248;   Pesticides:spirotetramat;   Reaxys:14441154


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spirotetramat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxo1 forkhead box O1 increases expression ISO spirotetramat results in increased expression of FOXO1 mRNA CTD PMID:27917277 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Vnn1 vanin 1 decreases expression ISO spirotetramat results in decreased expression of VNN1 mRNA CTD PMID:27917277 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        agrochemical 14436
          spirotetramat 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            carbamoyl group 17134
                                              carboxamide 17134
                                                lactam 8027
                                                  gamma-lactam 6266
                                                    spirotetramat 2
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