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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:spirotetramat
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Accession:CHEBI:81975 term browser browse the term
Definition:An azaspiro compound that is methoxycyclohexane which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 3 and 4 by 2,5-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively (the cis isomer). It is a proinsecticide (via hydrolysis of the ethyl carbonate group to give the corresponding 4-hydroxypyrrol-2-one, 'spirotetramat-enol') and is used for the control of a wide range of sucking insects on fruit and potato crops.
Synonyms:exact_synonym: (5s,8s)-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate
 related_synonym: Formula=C21H27NO5;   InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)/t15-,21+;   InChIKey=CLSVJBIHYWPGQY-GGYDESQDSA-N;   Movento;   SMILES=C1(=C(C=CC(=C1)C)C)C=2C(NC3(C2OC(OCC)=O)CCC(CC3)OC)=O;   Ultor;   cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate;   cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethylcarbonate;   ethyl cis-8-methoxy-2-oxo-3-(2,5-xylyl)-1-azaspiro[4.5]dec-3-en-4-yl carbonate
 xref: CAS:203313-25-1;   KEGG:C18807
 xref_mesh: MESH:C570705
 xref: PMID:22160136;   PMID:22531003;   PMID:22872376;   PMID:24772560;   PMID:24835551;   PMID:25281882;   PMID:26081578;   PMID:26304426;   PMID:26383737;   PMID:26449612;   PMID:26743711;   PMID:26898726;   PMID:27083908;   PMID:27788413;   PMID:27857899;   PMID:27917277;   PMID:27989834;   PMID:28139069;   PMID:28334236;   PPDB:1119;   Patent:EP2039248;   Pesticides:spirotetramat;   Reaxys:14441154


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spirotetramat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxo1 forkhead box O1 increases expression ISO spirotetramat results in increased expression of FOXO1 mRNA CTD PMID:27917277 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Vnn1 vanin 1 decreases expression ISO spirotetramat results in decreased expression of VNN1 mRNA CTD PMID:27917277 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        agrochemical 15039
          spirotetramat 2
Path 2
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        carboacyl group 17482
                                          univalent carboacyl group 17482
                                            carbamoyl group 17298
                                              carboxamide 17298
                                                lactam 8302
                                                  gamma-lactam 6585
                                                    spirotetramat 2
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