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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:octhilinone
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Accession:CHEBI:81936 term browser browse the term
Definition:A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union.
Synonyms:exact_synonym: 2-octyl-1,2-thiazol-3(2H)-one
 related_synonym: 2-Octyl-3(2H)-isothiazolone;   2-Octyl-3-isothiazolinone;   2-Octyl-3-isothiazolone;   2-Octyl-3-isothioazolone;   2-Octyl-4-isothiazolin-3-one;   2-n-Octyl-4-isothiazolin-3-one;   2-octyl-2H-isothiazol-3-one;   Formula=C11H19NOS;   InChI=1S/C11H19NOS/c1-2-3-4-5-6-7-9-12-11(13)8-10-14-12/h8,10H,2-7,9H2,1H3;   InChIKey=JPMIIZHYYWMHDT-UHFFFAOYSA-N;   Octyl-3(2H)-isothiazolone;   Octyl-4-isothiazol-3-one;   SMILES=CCCCCCCCn1sccc1=O
 xref: AGR:IND87046906;   CAS:26530-20-1;   KEGG:C18752
 xref_mesh: MESH:C035331
 xref: PMID:20960358;   PMID:23182288;   PPDB:489;   Pesticides:octhilinone;   Reaxys:1211137



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octhilinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO 2-n-octyl-4-isothiazolin-3-one results in increased activity of CASP3 protein CTD PMID:33806369 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cldn5 claudin 5 decreases expression ISO 2-n-octyl-4-isothiazolin-3-one results in decreased expression of CLDN5 protein CTD PMID:33806369 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO 2-n-octyl-4-isothiazolin-3-one results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO 2-n-octyl-4-isothiazolin-3-one results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO 2-n-octyl-4-isothiazolin-3-one results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO 2-n-octyl-4-isothiazolin-3-one results in decreased expression of TJP1 protein CTD PMID:33806369 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        xenobiotic 18778
          octhilinone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  heteroarene 17172
                                    monocyclic heteroarene 14893
                                      azole 14396
                                        thiazoles 1794
                                          1,2-thiazoles 684
                                            octhilinone 6
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