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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:81920 term browser browse the term
Definition:An aromatic amide that is acetamide in which the amino hydrogens have been replaced by a propan-2-yl and 4-fluorophenyl groups while the methyl hydrogen is replaced by a [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy group.
Synonyms:exact_synonym: N-(4-fluorophenyl)-N-(propan-2-yl)-2-{[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}acetamide
 related_synonym: 4'-fluoro-N-isopropyl-2-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yloxy]acetanilide;   Formula=C14H13F4N3O2S;   InChI=1S/C14H13F4N3O2S/c1-8(2)21(10-5-3-9(15)4-6-10)11(22)7-23-13-20-19-12(24-13)14(16,17)18/h3-6,8H,7H2,1-2H3;   InChIKey=IANUJLZYFUDJIH-UHFFFAOYSA-N;   SMILES=CC(C)N(C(=O)COc1nnc(s1)C(F)(F)F)c1ccc(F)cc1;   Thiafluamide
 xref: CAS:142459-58-3;   KEGG:C18731
 xref_mesh: MESH:C094127
 xref: PMID:24007479;   PPDB:331;   Patent:US2011152087;   Patent:US2011152089;   Patent:US2011160059;   Pesticides:flufenacet;   Reaxys:8787751;   Wikipedia:Flufenacet

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flufenacet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO FOE 5043 results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
affects activity
ISO FOE 5043 results in increased activity of NR1I2 protein
FOE 5043 affects the activity of NR1I2 protein
CTD PMID:20143881, PMID:23611293 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Tspo translocator protein affects activity EXP FOE 5043 affects the activity of TSPO protein CTD PMID:23611293 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          flufenacet 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                carbocyclic compound 18183
                                  benzenoid aromatic compound 17180
                                    benzenes 16922
                                      fluorobenzenes 1648
                                        monofluorobenzenes 1316
                                          flufenacet 3
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