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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:81843 term browser browse the term
Definition:A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens.
Synonyms:exact_synonym: 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine
 related_synonym: 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-alpha,alpha,alpha-trifluoro-2,6-dinitro-p-toluidine;   Formula=C13H4Cl2F6N4O4;   InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23);   InChIKey=UZCGKGPEKUCDTF-UHFFFAOYSA-N;   SMILES=[O-][N+](=O)c1cc(c(Cl)c(c1Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F;   Shirlan
 xref: CAS:79622-59-6;   KEGG:C18578
 xref_mesh: MESH:C075780
 xref: PMID:19837458;   PMID:21907236;   PMID:22465686;   PMID:23464902;   PMID:24427089;   PMID:24813983;   PMID:7774188;   PPDB:325;   Patent:NZ582589;   Patent:WO2011092618;   Pesticides:fluazinam;   Reaxys:4772672;   Wikipedia:Fluazinam

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fluazinam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO fluazinam results in increased expression of BAX protein CTD PMID:21907236 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO fluazinam results in decreased expression of BCL2 protein CTD PMID:21907236 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 increases activity ISO fluazinam results in increased activity of CASP3 protein CTD PMID:21907236 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO fluazinam results in decreased activity of DIO1 protein CTD PMID:29228274 PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO fluazinam results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO fluazinam results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO fluazinam results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
JBrowse link
G Tp53 tumor protein p53 increases expression ISO fluazinam results in increased expression of TP53 protein CTD PMID:21907236 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

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  CHEBI ontology 19911
    role 19887
      biological role 19885
        xenobiotic 18773
          fluazinam 8
Path 2
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  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19909
          baryon 19909
            nucleon 19909
              atomic nucleus 19909
                atom 19909
                  main group element atom 19859
                    main group molecular entity 19859
                      s-block molecular entity 19692
                        hydrogen molecular entity 19678
                          hydrides 19156
                            organic hydride 18707
                              organic fundamental parent 18707
                                hydrocarbon 18438
                                  halohydrocarbon 15511
                                    haloalkane 12294
                                      fluoroalkane 8090
                                        fluoromethanes 6758
                                          tetrafluoromethane 6758
                                            trifluoromethyl group 6758
                                              (trifluoromethyl)benzenes 6758
                                                fluazinam 8
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