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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:flutolanil
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Accession:CHEBI:81792 term browser browse the term
Definition:A member of the class of benzamides, obtained by formal condensation of the carboxy group of 2-(trifluoromethyl)benzoic acid with the amino group of 3-(ispropyloxy)aniline. A fungicide used to control a range of pathogens especially Rhizoctonia spp. on rice, turf and other crops.
Synonyms:exact_synonym: N-[3-(propan-2-yloxy)phenyl]-2-(trifluoromethyl)benzamide
 related_synonym: 3'-isopropoxy-2-trifloromethylbenzoic acid anilide;   Formula=C17H16F3NO2;   InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22);   InChIKey=PTCGDEVVHUXTMP-UHFFFAOYSA-N;   Moncut;   N-(3-(1-Methylethoxy)phenyl)-2-(trifluoromethyl)benzamide;   N-(3-isopropoxyphenyl)-2-(trifluoromethyl)benzamide;   NNF-136;   SMILES=CC(C)Oc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1;   alpha,alpha,alpha-Trifluoro-3'-isopropoxy-o-toluanilide;   o-trifluoromethyl-m'-isopropoxybenzoic anilide
 xref: CAS:66332-96-5;   KEGG:C18502
 xref_mesh: MESH:C475882
 xref: MetaCyc:CPD-15890;   PDBeChem:FTN;   PMID:21587472;   PPDB:352;   Pesticides:flutolanil;   Reaxys:2163858

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flutolanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression ISO flutolanil results in increased expression of CYP3A4 mRNA CTD PMID:17293382 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Esr1 estrogen receptor 1 decreases expression
multiple interactions		 ISO flutolanil results in decreased expression of ESR1 protein
flutolanil binds to and results in increased activity of ESR1 protein		 CTD PMID:17904202 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO flutolanil binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545 		JBrowse link
G Pgr progesterone receptor increases expression ISO flutolanil results in increased expression of PGR mRNA CTD PMID:17904202 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO flutolanil results in increased activity of PPARG protein CTD PMID:20143881 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO flutolanil results in increased expression of TFF1 mRNA CTD PMID:17904202 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      application 19406
        pesticide 16587
          antifungal agrochemical 8081
            flutolanil 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic group 18599
                              organic divalent group 18590
                                organodiyl group 18590
                                  carbonyl group 18505
                                    carbonyl compound 18505
                                      carboxylic acid 18157
                                        carboacyl group 17416
                                          univalent carboacyl group 17416
                                            carbamoyl group 17213
                                              carboxamide 17213
                                                monocarboxylic acid amide 14602
                                                  arenecarboxamide 6540
                                                    benzamides 6540
                                                      flutolanil 6
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