Erythropoietin - Ontology Report - Rat Genome Database

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of COX4I1 protein]

NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921

Creb1

cAMP responsive element binding protein 1

increases phosphorylation

EXP

Erythropoietin increases phosphorylation in Creb1 protein in ventral horn of spinal cord

RGD

PMID:17368520

RGD:155226865

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

citrate synthase

multiple interactions

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of CS protein]

NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421

Itgam

integrin subunit alpha M

decreases expression

Erythropoietin decreases expression of Itgam protein in hypoxic microglial cells

RGD

PMID:33104828

RGD:329902063

NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503

Nrf1

nuclear respiratory factor 1

multiple interactions
increases expression

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]]
Erythropoietin results in increased expression of NRF1 protein

NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328

Ppargc1a

PPARG coactivator 1 alpha

multiple interactions

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of and results in increased acetylation of PPARGC1A protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein]]

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

Sirt1

sirtuin 1

multiple interactions

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of and results in decreased activity of SIRT1 protein]; Erythropoietin results in increased expression of and results in increased activity of SIRT1 protein; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]]

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

Sod2

superoxide dismutase 2

multiple interactions
increases expression

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein]
Erythropoietin results in increased expression of SOD2 protein

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

Tfam

transcription factor A, mitochondrial

multiple interactions

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]]

NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292

Vdac1

voltage-dependent anion channel 1

multiple interactions

Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]]