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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Erythropoietin
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Accession:CHEBI:81579 term browser browse the term
Synonyms:related_synonym: EPO
 xref: CAS:11096-26-7;   KEGG:C18200
 xref_mesh: MESH:D004921


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Erythropoietin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of COX4I1 protein] CTD PMID:28456571 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cs citrate synthase multiple interactions ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of CS protein] CTD PMID:28456571 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
increases expression
ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]]
Erythropoietin results in increased expression of NRF1 protein
CTD PMID:28456571 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of and results in increased acetylation of PPARGC1A protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein]] CTD PMID:28456571 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of and results in decreased activity of SIRT1 protein]; Erythropoietin results in increased expression of and results in increased activity of SIRT1 protein; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of PPARGC1A protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]] CTD PMID:28456571 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein]
Erythropoietin results in increased expression of SOD2 protein
CTD PMID:28456571 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of TFAM protein]] CTD PMID:28456571 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]; SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of VDAC1 protein]] CTD PMID:28456571 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Erythropoietin 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Erythropoietin 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.