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Term:resolvin D2
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Accession:CHEBI:81565 term browser browse the term
Definition:A member of the class of resolvins that is (4Z,8E,10Z,12E,14E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 7, 16 and 17 (the 7S,16R,17S-stereoisomer).
Synonyms:exact_synonym: (4Z,7R,8E,10Z,12E,14E,16R,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid
 related_synonym: 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid;   Formula=C22H32O5;   InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20+,21-/m1/s1;   InChIKey=IKFAUGXNBOBQDM-XFMPMKITSA-N;   RVD2;   SMILES=C(C/C=C\\C[C@@H](/C=C/C=C\\C=C\\C=C\\[C@H]([C@H](C/C=C\\CC)O)O)O)C(O)=O
 xref: CAS:82864-77-5 "HMDB";   HMDB:HMDB0002294;   KEGG:C18179;   LIPID_MAPS_instance:LMFA04000007 "LIPID MAPS"
 xref_mesh: MESH:C545423
 xref: MetaCyc:CPD66-65;   PMID:19865173 "Europe PMC";   PMID:21724996 "Europe PMC";   PMID:22171045 "Europe PMC";   PMID:22844113 "Europe PMC";   PMID:22912397 "Europe PMC";   PMID:23110665 "Europe PMC";   PMID:23430978 "Europe PMC";   PMID:23723388 "Europe PMC";   PMID:24367439 "Europe PMC";   PMID:24890726 "Europe PMC";   PMID:25077525 "Europe PMC";   PMID:25777995 "Europe PMC";   PMID:25824039 "Europe PMC";   PMID:26195725 "Europe PMC";   PMID:26509319 "Europe PMC";   PMID:26878867 "Europe PMC";   PMID:27256622 "Europe PMC";   PMID:27507404 "Europe PMC";   PMID:27531933 "Europe PMC";   PMID:27559094 "Europe PMC";   PMID:27619672 "Europe PMC";   PMID:27860453 "Europe PMC";   PMID:27935998 "Europe PMC";   PMID:27994074 "Europe PMC";   PMID:28063958 "Europe PMC";   PMID:28086928 "Europe PMC";   Reaxys:9876619 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:133367

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resolvin D2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgal integrin subunit alpha L JBrowse link 1 198,744,053 198,781,745 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      application 19232
        anti-inflammatory agent 14910
          resolvin D2 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic acid 17921
                                        monocarboxylic acid 17256
                                          fatty acid 15817
                                            unsaturated fatty acid 889
                                              polyunsaturated fatty acid 646
                                                hydroxy polyunsaturated fatty acid 144
                                                  resolvin D2 14
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.