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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Octachlorostyrene
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Accession:CHEBI:81542 term browser browse the term
Definition:An organochlorine compound that has formula C8Cl8.
Synonyms:related_synonym: Formula=C8Cl8;   InChI=1S/C8Cl8/c9-2-1(4(11)8(15)16)3(10)6(13)7(14)5(2)12;   InChIKey=RUYUCCQRWINUHE-UHFFFAOYSA-N;   SMILES=ClC(Cl)=C(Cl)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl
 xref: CAS:29082-74-4;   KEGG:C18148
 xref_mesh: MESH:C014138


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Octachlorostyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR protein inhibits the reaction [octachlorostyrene results in increased activity of SULT1A1 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased activity of UGT1A6A protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of CYP2B10 mRNA]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of NR1I3 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of SULT1A1 mRNA]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of UGT1A6A mRNA] CTD PMID:19525444 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Casp3 caspase 3 increases activity ISO octachlorostyrene results in increased activity of CASP3 protein CTD PMID:18036774 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
ISO octachlorostyrene results in increased activity of CYP1A1 protein
octachlorostyrene results in increased expression of CYP1A1 mRNA
CTD PMID:19525444 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
ISO octachlorostyrene results in increased activity of CYP1A2 protein
octachlorostyrene results in increased expression of CYP1A2 mRNA
CTD PMID:19525444 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO octachlorostyrene results in increased expression of CYP2B10 mRNA
AHR protein inhibits the reaction [octachlorostyrene results in increased expression of CYP2B10 mRNA]
CTD PMID:19525444 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO octachlorostyrene results in increased expression of GSTM1 mRNA CTD PMID:18036774 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO octachlorostyrene results in increased expression of HMOX1 mRNA CTD PMID:18036774 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO octachlorostyrene inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO octachlorostyrene inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO octachlorostyrene results in increased expression of NQO1 mRNA CTD PMID:18036774 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases expression
increases activity
ISO AHR protein inhibits the reaction [octachlorostyrene results in increased expression of NR1I3 protein]
octachlorostyrene results in increased activity of NR1I3 protein
CTD PMID:19525444 PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      molecular entity 19811
        main group molecular entity 19708
          p-block molecular entity 19708
            halogen molecular entity 18165
              chlorine molecular entity 18006
                organochlorine compound 17729
                  Octachlorostyrene 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      p-block molecular entity 19708
                        carbon group molecular entity 19630
                          organic molecular entity 19620
                            heteroorganic entity 19283
                              organohalogen compound 17913
                                organochlorine compound 17729
                                  Octachlorostyrene 11
paths to the root