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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Octachlorostyrene
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Accession:CHEBI:81542 term browser browse the term
Definition:An organochlorine compound that has formula C8Cl8.
Synonyms:related_synonym: Formula=C8Cl8;   InChI=1S/C8Cl8/c9-2-1(4(11)8(15)16)3(10)6(13)7(14)5(2)12;   InChIKey=RUYUCCQRWINUHE-UHFFFAOYSA-N;   SMILES=ClC(Cl)=C(Cl)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl
 xref: CAS:29082-74-4;   KEGG:C18148
 xref_mesh: MESH:C014138


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Octachlorostyrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR protein inhibits the reaction [octachlorostyrene results in increased activity of SULT1A1 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased activity of UGT1A6A protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of CYP2B10 mRNA]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of NR1I3 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of SULT1A1 mRNA]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of UGT1A6A mRNA] CTD PMID:19525444 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Casp3 caspase 3 increases activity ISO octachlorostyrene results in increased activity of CASP3 protein CTD PMID:18036774 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
ISO octachlorostyrene results in increased activity of CYP1A1 protein
octachlorostyrene results in increased expression of CYP1A1 mRNA
CTD PMID:19525444 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
ISO octachlorostyrene results in increased activity of CYP1A2 protein
octachlorostyrene results in increased expression of CYP1A2 mRNA
CTD PMID:19525444 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO octachlorostyrene results in increased expression of CYP2B10 mRNA
AHR protein inhibits the reaction [octachlorostyrene results in increased expression of CYP2B10 mRNA]
CTD PMID:19525444 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO octachlorostyrene results in increased expression of GSTM1 mRNA CTD PMID:18036774 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO octachlorostyrene results in increased expression of HMOX1 mRNA CTD PMID:18036774 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO octachlorostyrene inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO octachlorostyrene inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO octachlorostyrene results in increased expression of NQO1 mRNA CTD PMID:18036774 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases expression
increases activity
ISO AHR protein inhibits the reaction [octachlorostyrene results in increased expression of NR1I3 protein]
octachlorostyrene results in increased activity of NR1I3 protein
CTD PMID:19525444, PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases expression
ISO AHR protein inhibits the reaction [octachlorostyrene results in increased activity of SULT1A1 protein]; AHR protein inhibits the reaction [octachlorostyrene results in increased expression of SULT1A1 mRNA] CTD PMID:19525444 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      molecular entity 19782
        main group molecular entity 19670
          p-block molecular entity 19670
            halogen molecular entity 18012
              chlorine molecular entity 17793
                organochlorine compound 17466
                  Octachlorostyrene 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      p-block molecular entity 19670
                        carbon group molecular entity 19572
                          organic molecular entity 19561
                            heteroorganic entity 19147
                              organohalogen compound 17713
                                organochlorine compound 17466
                                  Octachlorostyrene 12
paths to the root

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