Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(+)-nootkatone
go back to main search page
Accession:CHEBI:81377 term browser browse the term
Definition:A sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer).
Synonyms:exact_synonym: (4R,4aS,6R)-4,4a-dimethyl-6-(prop-1-en-2-yl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one
 related_synonym: Formula=C15H22O;   InChI=1S/C15H22O/c1-10(2)12-5-6-13-8-14(16)7-11(3)15(13,4)9-12/h8,11-12H,1,5-7,9H2,2-4H3/t11-,12-,15+/m1/s1;   InChIKey=WTOYNNBCKUYIKC-JMSVASOKSA-N;   SMILES=[C@@]12(C(CC[C@H](C1)C(C)=C)=CC(C[C@H]2C)=O)C
 xref: CAS:4674-50-4;   HMDB:HMDB0013687;   KEGG:C17914;   KNApSAcK:C00016987
 xref_mesh: MESH:C050302
 xref: PMID:11441443;   PMID:15962787;   PMID:16272746;   PMID:19333595;   PMID:19630428;   PMID:21354294;   PMID:22238870;   PMID:22308777;   PMID:23025184;   PMID:24704449;   PMID:24747046;   PMID:24938835;   PMID:25189516;   PMID:25326849;   Patent:US2012045806;   Wikipedia:Nootkatone


show annotations for term's descendants           Sort by:
 
(+)-nootkatone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO nootkatone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G LOC100912605 olfactory receptor 5D14-like multiple interactions ISO nootkatone binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        fragrance 848
          (+)-nootkatone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      ketone 16144
                                        alpha,beta-unsaturated ketone 8520
                                          enone 8520
                                            (+)-nootkatone 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.