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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycyrol
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Accession:CHEBI:80832 term browser browse the term
Definition:A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 1 and 9, a methoxy group at position 3 and a prenyl group at position 2 respectively.
Synonyms:exact_synonym: 3,9-dihydroxy-1-methoxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one
 related_synonym: 1,9-Dihydroxy-3-methoxy-2-prenylcoumestan;   Formula=C21H18O6;   InChI=1S/C21H18O6/c1-10(2)4-6-12-14(23)9-16-18(19(12)25-3)20-17(21(24)27-16)13-7-5-11(22)8-15(13)26-20/h4-5,7-9,22-23H,6H2,1-3H3;   InChIKey=LWESBHWAOZORCQ-UHFFFAOYSA-N;   Neoglycyrol;   SMILES=COc1c(CC=C(C)C)c(O)cc2oc(=O)c3c4ccc(O)cc4oc3c12
 xref: CAS:23013-84-5;   HMDB:HMDB0033882;   KEGG:C16968;   KNApSAcK:C00009777;   LIPID_MAPS_instance:LMPK12090044
 xref_mesh: MESH:C531349
 xref: PMID:25445757;   PMID:25614969


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glycyrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:18666753 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:18666753 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression		 ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
glycyrol results in increased expression of NFKBIA protein		 CTD PMID:18666753 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:18666753 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:18666753 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19909
    role 19880
      application 19720
        pharmaceutical 19558
          drug 19558
            antineoplastic agent 17846
              glycyrol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            heteroorganic entity 19540
                              organochalcogen compound 19301
                                organooxygen compound 19216
                                  ester 17582
                                    carboxylic ester 16981
                                      lactone 13311
                                        delta-lactone 4213
                                          coumestan 1787
                                            glycyrol 5
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