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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycyrol
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Accession:CHEBI:80832 term browser browse the term
Definition:A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 1 and 9, a methoxy group at position 3 and a prenyl group at position 2 respectively.
Synonyms:exact_synonym: 3,9-dihydroxy-1-methoxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one
 related_synonym: 1,9-Dihydroxy-3-methoxy-2-prenylcoumestan;   Formula=C21H18O6;   InChI=1S/C21H18O6/c1-10(2)4-6-12-14(23)9-16-18(19(12)25-3)20-17(21(24)27-16)13-7-5-11(22)8-15(13)26-20/h4-5,7-9,22-23H,6H2,1-3H3;   InChIKey=LWESBHWAOZORCQ-UHFFFAOYSA-N;   Neoglycyrol;   SMILES=COc1c(CC=C(C)C)c(O)cc2oc(=O)c3c4ccc(O)cc4oc3c12
 xref: CAS:23013-84-5;   HMDB:HMDB0033882;   KEGG:C16968;   KNApSAcK:C00009777;   LIPID_MAPS_instance:LMPK12090044
 xref_mesh: MESH:C531349
 xref: PMID:25445757;   PMID:25614969



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glycyrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:18666753 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:18666753 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
glycyrol results in increased expression of NFKBIA protein
CTD PMID:18666753 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:18666753 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO glycyrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:18666753 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        pharmaceutical 19565
          drug 19565
            antineoplastic agent 17770
              glycyrol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic ester 16506
                                        lactone 12533
                                          delta-lactone 3949
                                            coumestan 1783
                                              glycyrol 5
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