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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Cinobufotalin
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Accession:CHEBI:80806 term browser browse the term
Definition:A steroid lactone that has formula C26H34O7.
Synonyms:related_synonym: Formula=C26H34O7;   InChI=1S/C26H34O7/c1-14(27)32-21-20(15-4-5-19(29)31-13-15)24(3)10-7-17-18(26(24)22(21)33-26)8-11-25(30)12-16(28)6-9-23(17,25)2/h4-5,13,16-18,20-22,28,30H,6-12H2,1-3H3/t16-,17?,18?,20-,21+,22+,23+,24+,25-,26+/m0/s1;   InChIKey=KBKUJJFDSHBPPA-JTZFMNKUSA-N;   SMILES=CC(=O)O[C@H]1[C@H]2O[C@]22C3CC[C@]4(O)C[C@@H](O)CC[C@]4(C)C3CC[C@]2(C)[C@H]1c1ccc(=O)oc1
 xref: CAS:1108-68-5;   KEGG:C16932
 xref_mesh: MESH:C063451


show annotations for term's descendants           Sort by:
 
Cinobufotalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases activity ISO cinobufotalin results in increased activity of BAX protein CTD PMID:22898211 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bid BH3 interacting domain death agonist increases activity ISO cinobufotalin results in increased activity of BID protein CTD PMID:22898211 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp2 caspase 2 increases cleavage ISO cinobufotalin results in increased cleavage of CASP2 protein CTD PMID:22898211 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 increases cleavage ISO cinobufotalin results in increased cleavage of CASP3 protein CTD PMID:22898211 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage ISO cinobufotalin results in increased cleavage of CASP8 protein CTD PMID:22898211 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases cleavage ISO cinobufotalin results in increased cleavage of CASP9 protein CTD PMID:22898211 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO cinobufotalin results in increased expression of FAS protein CTD PMID:22898211 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    chemical entity 19781
      atom 19779
        nonmetal atom 19659
          carbon atom 19578
            organic molecular entity 19578
              lipid 17485
                steroid 13051
                  steroid lactone 412
                    Cinobufotalin 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic group 18620
                              organic divalent group 18611
                                organodiyl group 18611
                                  carbonyl group 18526
                                    carbonyl compound 18526
                                      carboxylic ester 15517
                                        lactone 9734
                                          steroid lactone 412
                                            bufanolide 76
                                              Cinobufotalin 7
paths to the root