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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:80790 term browser browse the term
Definition:A glycosyloxyflavone that is kaempferol attached to an alpha-L-rhamnosyl residue at position 3 via a glycosidic linkage.
Synonyms:exact_synonym: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside
 related_synonym: 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-ol;   5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl alpha-L-rhamnoside;   Formula=C21H20O10;   InChI=1S/C21H20O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-18,21-25,27-28H,1H3/t8-,15-,17+,18+,21-/m0/s1;   InChIKey=SOSLMHZOJATCCP-AEIZVZFYSA-N;   Kaempferin;   Kaempferol 3-O-alpha-L-rhamnopyranoside;   SMILES=C1=C(C=C(C2=C1OC(=C(C2=O)O[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O)C4=CC=C(C=C4)O)O)O;   kaempferol 3-O-alpha-L-rhamnoside;   kaempferol-3-rhamnoside;   kaempherol 3-O-alpha-rhamnoside
 alt_id: CHEBI:145298
 xref: CAS:482-39-3;   KEGG:C16911;   KNApSAcK:C00005140;   LIPID_MAPS_instance:LMPK12111842
 xref_mesh: MESH:C477954
 xref: PDBeChem:AFE;   PMID:23626759;   PMID:24423008;   PMID:24642906;   PMID:27287415;   PMID:27861739;   PMID:27992083;   PMID:29497935;   PMID:29715535;   PMID:29967287;   PMID:30080245;   PMID:30450965;   PMID:30990334;   PMID:31017255;   PMID:31323310;   PMID:31384828;   PMID:31401185;   Reaxys:1359648;   Wikipedia:Afzelin
 cyclic_relationship: is_conjugate_acid_of CHEBI:144433

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afzelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mitf melanocyte inducing transcription factor increases expression ISO afzelin results in increased expression of MITF mRNA; afzelin results in increased expression of MITF protein CTD PMID:27287415 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Tyr tyrosinase multiple interactions
increases expression
ISO afzelin results in increased expression of and results in increased activity of TYR protein
afzelin results in increased expression of TYR mRNA
CTD PMID:27287415 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Tyrp1 tyrosinase-related protein 1 increases expression ISO afzelin results in increased expression of TYRP1 mRNA; afzelin results in increased expression of TYRP1 protein CTD PMID:27287415 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        anti-inflammatory agent 16481
          afzelin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  oxacycle 17688
                                    benzopyran 11213
                                      1-benzopyran 10951
                                        flavonoid 6575
                                          flavones 4220
                                            hydroxyflavone 4203
                                              flavonols 4109
                                                7-hydroxyflavonol 4084
                                                  kaempferol 171
                                                    afzelin 3
paths to the root