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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tauroursodeoxycholic acid
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Accession:CHEBI:80774 term browser browse the term
Definition:A bile acid taurine conjugate derived from ursoodeoxycholic acid.
Synonyms:exact_synonym: 2-[(3alpha,7beta-dihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonic acid
 related_synonym: 2-(((3-alpha,5-beta,7-beta)-3,7-Dihydroxy-24-oxocholan-24-yl) amino)ethanesulfonic acid;   2-{[(3alpha,5beta,7beta)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethane-1-sulfonic acid;   3alpha,7beta-dihydroxy-5beta-cholanoyltaurine;   Formula=C26H45NO6S;   InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1;   InChIKey=BHTRKEVKTKCXOH-LBSADWJPSA-N;   N-(3-alpha,7-beta-Dihydroxy-5-beta-cholan-24-oyl)-Taurine;   N-(3alpha,7beta-dihydroxy-5beta-cholan-24-oyl)taurine;   N-ursodeoxycholoyltaurine;   SMILES=C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3([C@H](C[C@@]2(C[C@@H](C1)O)[H])O)[H])(CC[C@]4([H])[C@@H](CCC(NCCS(O)(=O)=O)=O)C)[H])C)[H])C;   TUDCA;   Taurolite;   UR 906;   Ursodeoxycholyltaurine
 alt_id: CHEBI:132326
 xref: CAS:14605-22-2;   HMDB:HMDB0000874;   KEGG:C16868;   LIPID_MAPS_instance:LMST05040015
 xref_mesh: MESH:C031655
 xref: MetaCyc:CPD-18799;   PDBeChem:5D5;   PMID:25664595;   PMID:26282527;   PMID:26427442;   PMID:26499839;   PMID:26541419;   PMID:26748055;   PMID:26759227;   PMID:26765262;   PMID:26907328;   PMID:26922713;   PMID:26988565;   PMID:27106542;   PMID:27124655;   PMID:27154200;   PMID:27219292;   Reaxys:3228312;   Wikipedia:Tauroursodeoxycholic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:132028


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tauroursodeoxycholic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP ursodoxicoltaurine results in decreased expression of A2M mRNA CTD PMID:15885361 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Aadat aminoadipate aminotransferase decreases expression EXP ursodoxicoltaurine results in decreased expression of AADAT mRNA CTD PMID:15885361 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Aatf apoptosis antagonizing transcription factor increases expression EXP ursodoxicoltaurine results in increased expression of AATF mRNA CTD PMID:15885361 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression
multiple interactions
increases expression
EXP ursodoxicoltaurine results in decreased expression of ABCB11 mRNA
ursodoxicoltaurine results in increased expression of and results in increased activity of ABCB11 protein
ursodoxicoltaurine results in increased expression of ABCB11 protein
CTD PMID:11672435 PMID:12644037 PMID:15885361 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein] CTD PMID:16101123 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
EXP ursodoxicoltaurine results in increased expression of and results in increased activity of ABCC2 protein
ursodoxicoltaurine results in increased expression of ABCC2 protein
CTD PMID:11672435 PMID:12644037 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP ursodoxicoltaurine results in increased expression of ABCC3 protein CTD PMID:11672435 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acly ATP citrate lyase decreases expression EXP ursodoxicoltaurine results in decreased expression of ACLY mRNA CTD PMID:15885361 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of ACSL1 mRNA CTD PMID:15885361 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of ACTN1 mRNA CTD PMID:15885361 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP ursodoxicoltaurine results in decreased expression of ADH1 mRNA CTD PMID:15885361 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adk adenosine kinase decreases expression EXP ursodoxicoltaurine results in decreased expression of ADK mRNA CTD PMID:15885361 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Agt angiotensinogen decreases expression
multiple interactions
EXP ursodoxicoltaurine results in decreased expression of AGT mRNA
ursodoxicoltaurine inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]]; ursodoxicoltaurine inhibits the reaction [AGT protein results in increased expression of FN1 protein]; ursodoxicoltaurine inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; ursodoxicoltaurine inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein]; ursodoxicoltaurine inhibits the reaction [AGT protein results in increased secretion of TGFB1 protein]
CTD PMID:15885361 PMID:25398788 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahr aryl hydrocarbon receptor increases abundance
increases secretion
ISO AHR gene mutant form results in increased abundance of ursodoxicoltaurine
AHR gene mutant form results in increased secretion of ursodoxicoltaurine
CTD PMID:32679164 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression EXP ursodoxicoltaurine results in increased expression of AKR1B8 mRNA CTD PMID:15885361 NCBI chr 4:62,997,241...63,009,815 JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 decreases expression EXP ursodoxicoltaurine results in decreased expression of AKR1D1 mRNA CTD PMID:15885361 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein]; ursodoxicoltaurine results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:12721362 PMID:25398788 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Amy1a amylase, alpha 1A decreases expression EXP ursodoxicoltaurine results in decreased expression of AMY1A mRNA CTD PMID:15885361 NCBI chr 2:201,382,678...201,397,487
Ensembl chr 2:201,382,675...201,397,816
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 affects expression
decreases expression
EXP ursodoxicoltaurine affects the expression of APAF1 mRNA; ursodoxicoltaurine affects the expression of APAF1 protein
ursodoxicoltaurine results in decreased expression of APAF1 mRNA
CTD PMID:15885361 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP ursodoxicoltaurine results in decreased expression of APOA1 mRNA CTD PMID:15885361 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [ursodoxicoltaurine co-treated with Indomethacin] results in increased expression of APOB mRNA; [ursodoxicoltaurine co-treated with Tunicamycin] results in increased expression of APOB mRNA; ursodoxicoltaurine inhibits the reaction [Allopurinol results in decreased secretion of APOB protein]; ursodoxicoltaurine inhibits the reaction [Fluorouracil results in decreased expression of APOB mRNA]; ursodoxicoltaurine inhibits the reaction [Rifampin results in decreased expression of APOB mRNA]; ursodoxicoltaurine inhibits the reaction [Tunicamycin results in decreased secretion of APOB protein] CTD PMID:32535746 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO
EXP
ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP2 protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP6 protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of TRP53 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased activity of CASP2 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased activity of CASP6 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased expression of TRP53 protein]
ursodoxicoltaurine affects the reaction [APP protein modified form affects the localization of NR3C2 protein]; ursodoxicoltaurine inhibits the reaction [[APP protein modified form results in increased activity of CASP3 protein] which results in increased cleavage of MAPT protein]; ursodoxicoltaurine inhibits the reaction [APP protein modified form results in increased activity of CASP3 protein]
CTD PMID:16728529 PMID:16923170 PMID:18368144 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp8 aquaporin 8 decreases expression EXP ursodoxicoltaurine results in decreased expression of AQP8 mRNA CTD PMID:15885361 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Arg1 arginase 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of ARG1 mRNA CTD PMID:15885361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression EXP ursodoxicoltaurine results in increased expression of ARL1 mRNA CTD PMID:15885361 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G As3mt arsenite methyltransferase decreases expression EXP ursodoxicoltaurine results in decreased expression of AS3MT mRNA CTD PMID:15885361 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
JBrowse link
G Atf4 activating transcription factor 4 decreases expression
multiple interactions
ISO ursodoxicoltaurine results in decreased expression of ATF4 mRNA
ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of ATF4 mRNA]
ursodoxicoltaurine inhibits the reaction [Quercetin results in increased expression of ATF4 protein]
CTD PMID:24312631 PMID:25611565 PMID:28223344 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO
EXP
ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Quercetin results in increased activity of ATF6 protein]
ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of ATF6 mRNA]
CTD PMID:20165829 PMID:25611565 PMID:28223344 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases phosphorylation
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and results in decreased activity of BAD protein]; ursodoxicoltaurine results in increased phosphorylation of and results in decreased activity of BAD protein
ursodoxicoltaurine results in increased phosphorylation of and affects the localization of BAD protein; Wortmannin inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and affects the localization of BAD protein]
ursodoxicoltaurine results in increased phosphorylation of BAD protein
CTD PMID:12721362 PMID:15190125 PMID:17559149 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression
increases expression
ISO
EXP
ursodoxicoltaurine affects the localization of and results in decreased susceptibility to BAX protein; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased expression of BAX protein]
ursodoxicoltaurine results in decreased expression of BAX protein
ursodoxicoltaurine inhibits the reaction [3-nitropropionic acid affects the localization of BAX protein]; ursodoxicoltaurine inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]
ursodoxicoltaurine results in increased expression of BAX protein
CTD PMID:11080188 PMID:12627974 PMID:12721362 PMID:15255934 PMID:16923170 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
EXP
ISO
ursodoxicoltaurine results in increased expression of BCL2 mRNA; ursodoxicoltaurine results in increased expression of BCL2 protein
ursodoxicoltaurine inhibits the reaction [Gentamicins results in decreased expression of BCL2 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in decreased expression of BCL2 protein]
ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [Quercetin results in decreased expression of BCL2 protein]
CTD PMID:12721362 PMID:15255934 PMID:16923170 PMID:25611565 PMID:29751043 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of BCL2L1 mRNA CTD PMID:12721362 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G C4b complement C4B (Chido blood group) decreases expression EXP ursodoxicoltaurine results in decreased expression of C4B mRNA CTD PMID:15885361 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Calr calreticulin multiple interactions EXP ursodoxicoltaurine promotes the reaction [Cisplatin results in increased expression of CALR mRNA] CTD PMID:33631298 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Canx calnexin multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Tunicamycin results in increased expression of CANX protein] CTD PMID:27588471 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp12 caspase 12 multiple interactions ISO
EXP
ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein]
ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased cleavage of CASP12 protein]; ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of CASP12 mRNA]
CTD PMID:12198651 PMID:33631298 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp2 caspase 2 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP2 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased activity of CASP2 protein] CTD PMID:16923170 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
EXP
ISO
ursodoxicoltaurine inhibits the reaction [[APP protein modified form results in increased activity of CASP3 protein] which results in increased cleavage of MAPT protein]; ursodoxicoltaurine inhibits the reaction [APP protein modified form results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [Neurotoxins results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]
ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of CASP3 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of CASP3 protein]
ursodoxicoltaurine inhibits the reaction [Quercetin promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; ursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased cleavage of and results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [Taurodeoxycholic Acid results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]
ursodoxicoltaurine results in decreased activity of CASP3 protein
CTD PMID:12198651 PMID:12773247 PMID:15190125 PMID:15222754 PMID:17436368 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased cleavage of and results in increased activity of CASP4 protein] CTD PMID:17559149 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP6 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased activity of CASP6 protein] CTD PMID:16923170 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased activity of CASP7 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein] CTD PMID:12198651 PMID:17559149 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Chenodeoxycholic Acid co-treated with ursodoxicoltaurine] results in increased activity of CASP9 protein; ursodoxicoltaurine inhibits the reaction [Quercetin promotes the reaction [Cisplatin results in increased cleavage of CASP9 protein]]; ursodoxicoltaurine inhibits the reaction [Taurodeoxycholic Acid results in increased activity of CASP9 protein] CTD PMID:12773247 PMID:14976352 PMID:25611565 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of CCN2 mRNA CTD PMID:15885361 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
EXP ursodoxicoltaurine inhibits the reaction [Deoxycholic Acid results in increased expression of CCND1 protein]
ursodoxicoltaurine results in decreased expression of CCND1 mRNA; ursodoxicoltaurine results in decreased expression of CCND1 protein
CTD PMID:15885361 PMID:17431217 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdh17 cadherin 17 decreases expression EXP ursodoxicoltaurine results in decreased expression of CDH17 mRNA CTD PMID:15885361 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Cdh2 cadherin 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of CDH2 mRNA CTD PMID:15885361 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP ursodoxicoltaurine results in increased expression of CEBPD mRNA CTD PMID:15885361 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Xylitol results in increased expression of CHAC1 protein] CTD PMID:32275922 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of CITED2 mRNA CTD PMID:15885361 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of CPS1 mRNA CTD PMID:15885361 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and results in increased activity of CREB1 protein]; calphostin C inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and results in increased activity of CREB1 protein]; KN 62 inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and results in increased activity of CREB1 protein]; ursodoxicoltaurine results in increased phosphorylation of and results in increased activity of CREB1 protein CTD PMID:15861431 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cs citrate synthase multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in decreased activity of CS protein]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in decreased expression of CS mRNA] CTD PMID:28223344 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP ursodoxicoltaurine results in decreased expression of CSAD mRNA CTD PMID:15885361 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP ursodoxicoltaurine results in decreased expression of CTH mRNA CTD PMID:15885361 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP1A2 mRNA CTD PMID:15885361 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP27A1 mRNA CTD PMID:15885361 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP2A2 mRNA CTD PMID:15885361 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP2B3 mRNA CTD PMID:15885361 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP2C12 mRNA CTD PMID:15885361 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP2F4 mRNA CTD PMID:15885361 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of CYP4F1 mRNA CTD PMID:15885361 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP
ISO
ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of DDIT3 protein]
ursodoxicoltaurine inhibits the reaction [2,4-dichlorophenol results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of DDIT3 mRNA]
ursodoxicoltaurine inhibits the reaction [Quercetin results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [ursolic acid results in increased expression of DDIT3 protein]
CTD PMID:23544086 PMID:24802810 PMID:25611565 PMID:27853103 PMID:28223344 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression EXP ursodoxicoltaurine results in decreased expression of DPP4 mRNA CTD PMID:15885361 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G E2f1 E2F transcription factor 1 increases expression
decreases expression
EXP ursodoxicoltaurine results in increased expression of E2F1 mRNA
ursodoxicoltaurine results in decreased expression of E2F1 protein
CTD PMID:15255934 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Edn1 endothelin 1 decreases expression ISO ursodoxicoltaurine results in decreased expression of EDN1 protein CTD PMID:15556138 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26803847 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Quercetin results in increased phosphorylation of EIF2S1 protein]; ursodoxicoltaurine inhibits the reaction [ursolic acid results in increased phosphorylation of EIF2S1 protein] CTD PMID:24802810 PMID:25611565 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of ENPP1 mRNA CTD PMID:15885361 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Ergic3 ERGIC and golgi 3 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Tunicamycin results in decreased expression of ERGIC3 protein] CTD PMID:27588471 NCBI chr 3:144,525,059...144,534,813
Ensembl chr 3:144,525,092...144,534,813
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Dronabinol results in increased expression of ESRRG mRNA] CTD PMID:31054322 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO ursodoxicoltaurine results in decreased expression of FABP4 mRNA CTD PMID:24312631 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of FADS1 mRNA CTD PMID:15885361 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fads3 fatty acid desaturase 3 decreases expression EXP ursodoxicoltaurine results in decreased expression of FADS3 mRNA CTD PMID:15885361 NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769
JBrowse link
G Fah fumarylacetoacetate hydrolase decreases expression EXP ursodoxicoltaurine results in decreased expression of FAH mRNA CTD PMID:15885361 NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP ursodoxicoltaurine results in decreased expression of FAS mRNA CTD PMID:14623915 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Dronabinol results in increased expression of FLT1 mRNA] CTD PMID:31054322 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 decreases expression EXP ursodoxicoltaurine results in decreased expression of FMO3 mRNA CTD PMID:15885361 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fn1 fibronectin 1 decreases expression
multiple interactions
EXP ursodoxicoltaurine results in decreased expression of FN1 mRNA
ursodoxicoltaurine inhibits the reaction [AGT protein results in increased expression of FN1 protein]
CTD PMID:15885361 PMID:25398788 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Taurolithocholic Acid results in increased expression of FOS mRNA] CTD PMID:18164257 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol results in decreased acetylation of FOXO1 protein] CTD PMID:23544086 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase decreases expression EXP ursodoxicoltaurine results in decreased expression of FTCD mRNA CTD PMID:15885361 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of G6PC1 mRNA]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of G6PC1 protein] CTD PMID:23544086 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression EXP ursodoxicoltaurine results in decreased expression of GAMT mRNA CTD PMID:15885361 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gckr glucokinase regulator decreases expression EXP ursodoxicoltaurine results in decreased expression of GCKR mRNA CTD PMID:15885361 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of GLUD1 mRNA CTD PMID:15885361 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 decreases expression ISO ursodoxicoltaurine results in decreased expression of GPBAR1 mRNA CTD PMID:24312631 NCBI chr 9:75,862,151...75,863,140
Ensembl chr 9:75,860,677...75,863,168
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases expression EXP ursodoxicoltaurine results in decreased expression of GSTA5 mRNA CTD PMID:15885361 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression EXP ursodoxicoltaurine results in decreased expression of GSTM3 mRNA CTD PMID:15885361 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP ursodoxicoltaurine results in increased expression of GSTP1 mRNA CTD PMID:15885361 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression EXP ursodoxicoltaurine results in decreased expression of HAAO mRNA CTD PMID:15885361 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression EXP ursodoxicoltaurine results in decreased expression of HADH mRNA CTD PMID:15885361 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression EXP ursodoxicoltaurine results in increased expression of HBP1 mRNA CTD PMID:15885361 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol promotes the reaction [HDAC3 protein binds to HDAC4 protein binds to HDAC5 protein binds to HDAC7 protein]] CTD PMID:23544086 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hdac4 histone deacetylase 4 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol promotes the reaction [HDAC3 protein binds to HDAC4 protein binds to HDAC5 protein binds to HDAC7 protein]]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of HDAC4 protein] CTD PMID:23544086 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol promotes the reaction [HDAC3 protein binds to HDAC4 protein binds to HDAC5 protein binds to HDAC7 protein]]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of HDAC5 protein] CTD PMID:23544086 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Hdac7 histone deacetylase 7 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol promotes the reaction [HDAC3 protein binds to HDAC4 protein binds to HDAC5 protein binds to HDAC7 protein]]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of HDAC7 protein] CTD PMID:23544086 NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Hdhd2 haloacid dehalogenase-like hydrolase domain containing 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of HDHD2 mRNA CTD PMID:15885361 NCBI chr18:70,475,037...70,526,471
Ensembl chr18:70,474,926...70,526,470
JBrowse link
G Hpn hepsin decreases expression EXP ursodoxicoltaurine results in decreased expression of HPN mRNA CTD PMID:15885361 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Hrg histidine-rich glycoprotein decreases expression EXP ursodoxicoltaurine results in decreased expression of HRG mRNA CTD PMID:15885361 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression
multiple interactions
decreases abundance
EXP
ISO
ursodoxicoltaurine results in decreased expression of HSD11B1 mRNA
ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA]
HSD11B1 gene mutant form results in decreased abundance of ursodoxicoltaurine
CTD PMID:15885361 PMID:25061560 PMID:26803847 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP ursodoxicoltaurine results in decreased expression of HSD17B6 mRNA CTD PMID:15885361 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP
ISO
ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]
ursodoxicoltaurine inhibits the reaction [2,4-dichlorophenol results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [2,4-dichlorophenol results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of HSPA5 mRNA]
ursodoxicoltaurine results in increased expression of HSPA5 protein
ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Quercetin results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [ursolic acid results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Xylitol results in increased expression of HSPA5 protein]
CTD PMID:12198651 PMID:20165829 PMID:24802810 PMID:25160872 PMID:25611565 More... NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of IGF1 mRNA CTD PMID:15885361 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP ursodoxicoltaurine results in increased expression of IGFBP1 mRNA CTD PMID:15885361 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Il10 interleukin 10 increases abundance ISO IL10 gene mutant form results in increased abundance of ursodoxicoltaurine CTD PMID:27580383 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein] CTD PMID:29031535 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein] CTD PMID:29031535 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] CTD PMID:20165829 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of ITPR1 mRNA]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of ITPR1 mRNA] CTD PMID:28223344 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of ITPR2 mRNA]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of ITPR2 mRNA] CTD PMID:28223344 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Taurolithocholic Acid results in increased expression of JUN mRNA] CTD PMID:18164257 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kng2 kininogen 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of KNG2 mRNA CTD PMID:15885361 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Lgals5 galectin 5 decreases expression EXP ursodoxicoltaurine results in decreased expression of LGALS5 mRNA CTD PMID:15885361 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153
JBrowse link
G Lgals9 galectin 9 decreases expression EXP ursodoxicoltaurine results in decreased expression of LGALS9 mRNA CTD PMID:15885361 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Limk2 LIM domain kinase 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of LIMK2 mRNA CTD PMID:15885361 NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007
JBrowse link
G Lmbrd1 LMBR1 domain containing 1 increases expression EXP ursodoxicoltaurine results in increased expression of LMBRD1 mRNA CTD PMID:15885361 NCBI chr 9:27,096,387...27,178,095
Ensembl chr 9:27,096,297...27,178,090
JBrowse link
G Lox lysyl oxidase decreases expression EXP ursodoxicoltaurine results in decreased expression of LOX mRNA CTD PMID:15885361 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Maob monoamine oxidase B decreases expression EXP ursodoxicoltaurine results in decreased expression of MAOB mRNA CTD PMID:15885361 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions EXP ursodoxicoltaurine inhibits the reaction [[APP protein modified form results in increased activity of CASP3 protein] which results in increased cleavage of MAPT protein] CTD PMID:18368144 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Masp2 MBL associated serine protease 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of MASP2 mRNA CTD PMID:15885361 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP ursodoxicoltaurine results in increased expression of MDM2 mRNA CTD PMID:15885361 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mef2a myocyte enhancer factor 2a multiple interactions ISO
EXP
ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein] CTD PMID:20165829 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of MFN2 mRNA] CTD PMID:28223344 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO ursodoxicoltaurine inhibits the reaction [ursolic acid results in decreased phosphorylation of MTOR protein] CTD PMID:24802810 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of MX2 mRNA CTD PMID:15885361 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
JBrowse link
G Nfia nuclear factor I/A decreases expression EXP ursodoxicoltaurine results in decreased expression of NFIA mRNA CTD PMID:15885361 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP ursodoxicoltaurine results in increased expression of NFKBIA protein CTD PMID:12721362 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] CTD PMID:29031535 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of NOS2 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of NOS2 protein] CTD PMID:29751043 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP ursodoxicoltaurine results in increased expression of NR1D2 mRNA CTD PMID:15885361 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO
EXP
ursodoxicoltaurine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 mRNA]; ursodoxicoltaurine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 protein]
[ursodoxicoltaurine co-treated with TGFB1 protein] results in increased localization of NR3C1 protein
CTD PMID:15222754 PMID:15885359 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 affects binding
increases expression
increases localization
multiple interactions
EXP ursodoxicoltaurine binds to NR3C2 protein
ursodoxicoltaurine results in increased expression of NR3C2 mRNA
ursodoxicoltaurine results in increased localization of NR3C2 protein
[ursodoxicoltaurine binds to NR3C2 protein] which affects the localization of NR3C2 protein; [ursodoxicoltaurine co-treated with TGFB1 protein] results in increased localization of NR3C2 protein; ursodoxicoltaurine affects the reaction [APP protein modified form affects the localization of NR3C2 protein]; ursodoxicoltaurine inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 mRNA]; ursodoxicoltaurine inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 protein]
CTD PMID:15222754 PMID:16728529 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Nup62 nucleoporin 62 increases expression EXP ursodoxicoltaurine results in increased expression of NUP62 mRNA CTD PMID:15885361 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of OS9 mRNA] CTD PMID:33631298 NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745
JBrowse link
G Otc ornithine transcarbamylase decreases expression EXP ursodoxicoltaurine results in decreased expression of OTC mRNA CTD PMID:15885361 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
G Pacs2 phosphofurin acidic cluster sorting protein 2 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of PACS2 mRNA] CTD PMID:28223344 NCBI chr 6:132,096,992...132,156,702
Ensembl chr 6:132,096,901...132,154,583
JBrowse link
G Pah phenylalanine hydroxylase decreases expression EXP ursodoxicoltaurine results in decreased expression of PAH mRNA CTD PMID:15885361 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Chenodeoxycholic Acid co-treated with ursodoxicoltaurine] results in increased cleavage of PARP1 protein; ursodoxicoltaurine inhibits the reaction [Quercetin promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]] CTD PMID:14976352 PMID:25611565 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pc pyruvate carboxylase multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased activity of PC protein] CTD PMID:28223344 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol results in decreased acetylation of PCK1 protein]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of PCK1 mRNA]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of PCK1 protein] CTD PMID:23544086 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of PDLIM1 mRNA CTD PMID:15885361 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase decreases expression EXP ursodoxicoltaurine results in decreased expression of PECR mRNA CTD PMID:15885361 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase decreases expression EXP ursodoxicoltaurine results in decreased expression of PHYH mRNA CTD PMID:15885361 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
JBrowse link
G Por cytochrome p450 oxidoreductase affects abundance ISO POR gene mutant form affects the abundance of ursodoxicoltaurine CTD PMID:25034404 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases abundance ISO PPARA gene mutant form results in decreased abundance of ursodoxicoltaurine CTD PMID:29175453 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO
EXP
ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] CTD PMID:20165829 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of BCL2 protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP2 protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased activity of CASP6 protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of BAX protein]; ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of TRP53 protein] CTD PMID:16923170 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of RB1 protein CTD PMID:15255934 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rnf138 ring finger protein 138 increases expression EXP ursodoxicoltaurine results in increased expression of RNF138 mRNA CTD PMID:15885361 NCBI chr18:12,291,557...12,315,931 JBrowse link
G RT1-EC2 RT1 class Ib, locus EC2 increases expression EXP ursodoxicoltaurine results in increased expression of RT1-EC2 mRNA CTD PMID:15885361
G S100a6 S100 calcium binding protein A6 decreases expression EXP ursodoxicoltaurine results in decreased expression of S100A6 mRNA CTD PMID:15885361 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G Scarb2 scavenger receptor class B, member 2 increases expression EXP ursodoxicoltaurine results in increased expression of SCARB2 mRNA CTD PMID:15885361 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP ursodoxicoltaurine results in decreased expression of SCD1 mRNA CTD PMID:15885361 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scp2 sterol carrier protein 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of SCP2 mRNA CTD PMID:15885361 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 increases expression EXP ursodoxicoltaurine results in increased expression of SERP1 mRNA CTD PMID:15885361 NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116
JBrowse link
G Serpina1 serpin family A member 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased activity of CASP7 protein]; ursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased cleavage of and results in increased activity of CASP3 protein]; ursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased cleavage of and results in increased activity of CASP4 protein] CTD PMID:17559149 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpind1 serpin family D member 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of SERPIND1 mRNA CTD PMID:15885361 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 decreases expression EXP ursodoxicoltaurine results in decreased expression of SH3BP5 mRNA CTD PMID:15885361 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Sirt2 sirtuin 2 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of SIRT2 protein] CTD PMID:23544086 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases expression EXP ursodoxicoltaurine results in increased expression of SLC10A2 protein CTD PMID:11672435 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases expression EXP ursodoxicoltaurine results in decreased expression of SLC22A8 mRNA CTD PMID:15885361 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc26a1 solute carrier family 26 member 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of SLC26A1 mRNA CTD PMID:15885361 NCBI chr14:1,040,565...1,045,851
Ensembl chr14:1,040,243...1,045,849
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of SLC27A2 mRNA CTD PMID:15885361 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP
ISO
ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein] CTD PMID:20165829 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc37a4 solute carrier family 37 member 4 decreases expression EXP ursodoxicoltaurine results in decreased expression of SLC37A4 mRNA CTD PMID:15885361 NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
JBrowse link
G Slc38a3 solute carrier family 38, member 3 decreases expression EXP ursodoxicoltaurine results in decreased expression of SLC38A3 mRNA CTD PMID:15885361 NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression EXP ursodoxicoltaurine results in increased expression of SLC6A9 mRNA CTD PMID:15885361 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Smad3 SMAD family member 3 increases abundance ISO SMAD3 protein results in increased abundance of ursodoxicoltaurine CTD PMID:23034213 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Snca synuclein alpha multiple interactions ISO 3-Hydroxybutyric Acid promotes the reaction [ursodoxicoltaurine inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone]]; ursodoxicoltaurine inhibits the reaction [SNCA protein results in increased susceptibility to Rotenone] CTD PMID:16239214 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] CTD PMID:25398788 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Quercetin results in decreased phosphorylation of STAT3 protein] CTD PMID:25611565 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stmn1 stathmin 1 increases expression EXP ursodoxicoltaurine results in increased expression of STMN1 mRNA CTD PMID:15885361 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of SULT1A1 mRNA CTD PMID:15885361 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of SULT1B1 mRNA CTD PMID:15885361 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Tagln transgelin decreases expression EXP ursodoxicoltaurine results in decreased expression of TAGLN mRNA CTD PMID:15885361 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases expression EXP ursodoxicoltaurine results in decreased expression of TDO2 mRNA CTD PMID:15885361 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [ursodoxicoltaurine co-treated with TGFB1 protein] results in increased localization of NR3C1 protein; [ursodoxicoltaurine co-treated with TGFB1 protein] results in increased localization of NR3C2 protein; ursodoxicoltaurine inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]]; ursodoxicoltaurine inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA]; ursodoxicoltaurine inhibits the reaction [AGT protein results in increased secretion of TGFB1 protein]; ursodoxicoltaurine inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 mRNA]; ursodoxicoltaurine inhibits the reaction [TGFB1 protein results in decreased expression of NR3C2 protein]; ursodoxicoltaurine inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein] CTD PMID:15222754 PMID:25398788 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression EXP ursodoxicoltaurine results in decreased expression of TGFBI mRNA CTD PMID:15885361 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Tgm2 transglutaminase 2 decreases expression EXP ursodoxicoltaurine results in decreased expression of TGM2 mRNA CTD PMID:15885361 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP ursodoxicoltaurine results in decreased expression of THRSP mRNA CTD PMID:15885361 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 decreases expression EXP ursodoxicoltaurine results in decreased expression of TM4SF4 mRNA CTD PMID:15885361 NCBI chr 2:141,570,321...141,621,263
Ensembl chr 2:141,481,902...141,621,200
JBrowse link
G Tmem37 transmembrane protein 37 decreases expression EXP ursodoxicoltaurine results in decreased expression of TMEM37 mRNA CTD PMID:15885361 NCBI chr13:31,184,322...31,191,477
Ensembl chr13:31,171,355...31,191,077
JBrowse link
G Tp53 tumor protein p53 multiple interactions
affects response to substance
EXP
ISO
ursodoxicoltaurine inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]; ursodoxicoltaurine results in increased expression of and results in increased stability of TP53 protein
ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of TRP53 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased expression of TRP53 protein]
TP53 protein affects the susceptibility to ursodoxicoltaurine
CTD PMID:15255934 PMID:16923170 PMID:17431217 PMID:17881359 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 multiple interactions EXP ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of UGGT1 mRNA]; ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of UGGT1 protein] CTD PMID:33631298 NCBI chr 9:38,355,229...38,468,473
Ensembl chr 9:38,359,089...38,468,467
JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B decreases expression EXP ursodoxicoltaurine results in decreased expression of UGT2B mRNA CTD PMID:15885361 NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776
JBrowse link
G Upb1 beta-ureidopropionase 1 decreases expression EXP ursodoxicoltaurine results in decreased expression of UPB1 mRNA CTD PMID:15885361 NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of VDAC1 mRNA] CTD PMID:28223344 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO ursodoxicoltaurine inhibits the reaction [Dronabinol results in increased expression of VEGFA mRNA] CTD PMID:31054322 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions EXP
ISO
ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]
ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Quercetin results in increased splicing of XBP1 mRNA]
CTD PMID:20165829 PMID:25611565 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link

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  CHEBI ontology 19812
    role 19761
      application 19471
        anti-inflammatory agent 15836
          tauroursodeoxycholic acid 190
Path 2
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic polycyclic compound 16535
                                  steroid 13057
                                    steroid fundamental parent 12693
                                      cholane 942
                                        cholanoid 942
                                          cholanic acids 926
                                            cholanic acid 926
                                              5beta-cholanic acid 926
                                                hydroxy-5beta-cholanic acid 926
                                                  dihydroxy-5beta-cholanic acid 774
                                                    ursodeoxycholic acid 389
                                                      tauroursodeoxycholic acid 190
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