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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenoxyacetic acid
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Accession:CHEBI:8075 term browser browse the term
Definition:A monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes.
Synonyms:related_synonym: Formula=C8H8O3;   Glycol acid phenyl ether;   InChI=1S/C8H8O3/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2,(H,9,10);   InChIKey=LCPDWSOZIOUXRV-UHFFFAOYSA-N;   POA;   Phenoxyacetate;   Phenoxyessigsaeure;   SMILES=OC(=O)COc1ccccc1;   phenoxacetic acid;   phenoxyethanoic acid
 xref: Beilstein:907949;   CAS:122-59-8;   Gmelin:142730;   HMDB:HMDB0031609;   KEGG:C02181;   PDBeChem:06Y;   PMID:14687482;   PMID:23838187;   PMID:26188115;   PMID:26452788;   Reaxys:907949
 cyclic_relationship: is_conjugate_acid_of CHEBI:38846


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(2,4,5-trichlorophenoxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCA7 mRNA CTD PMID:18579281 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA; 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 protein
Alpha-Amanitin inhibits the reaction [2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA]
CTD PMID:10377250, PMID:16426233 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acap3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ACAP3 mRNA CTD PMID:18579281 NCBI chr 5:173,340,060...173,354,756
Ensembl chr 5:173,340,060...173,354,755
JBrowse link
G Acer2 alkaline ceramidase 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ACER2 mRNA CTD PMID:18579281 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Adgrb2 adhesion G protein-coupled receptor B2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ADGRB2 mRNA CTD PMID:18579281 NCBI chr 5:148,168,530...148,231,587
Ensembl chr 5:148,193,710...148,231,587
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ADH4 mRNA CTD PMID:18579281 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of ALPI mRNA CTD PMID:18579281 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Ar androgen receptor affects binding EXP 2,4,5-Trichlorophenoxyacetic Acid binds to AR protein CTD PMID:14565775 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgap32 Rho GTPase activating protein 32 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ARHGAP32 mRNA CTD PMID:18579281 NCBI chr 8:33,131,874...33,392,198
Ensembl chr 8:33,239,139...33,392,305
JBrowse link
G Arsg arylsulfatase G increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ARSG mRNA CTD PMID:18579281 NCBI chr10:97,722,550...97,859,975
Ensembl chr10:97,771,264...97,863,311
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of BASP1 mRNA CTD PMID:18579281 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of C1QTNF4 mRNA CTD PMID:18579281 NCBI chr 3:79,713,580...79,718,018
Ensembl chr 3:79,713,567...79,718,025
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CACNB3 mRNA CTD PMID:18579281 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CAMK1D mRNA CTD PMID:18579281 NCBI chr17:76,532,611...76,938,956
Ensembl chr17:76,532,611...76,938,956
JBrowse link
G Capn6 calpain 6 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of CAPN6 mRNA CTD PMID:18579281 NCBI chr  X:115,049,113...115,073,824
Ensembl chr  X:115,049,154...115,073,890
JBrowse link
G Cdh1 cadherin 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CDH1 mRNA CTD PMID:18579281 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CIRBP mRNA CTD PMID:18579281 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
JBrowse link
G Ckm creatine kinase, M-type increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CKM mRNA CTD PMID:18579281 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of COL15A1 mRNA CTD PMID:18579281 NCBI chr 5:62,840,360...62,950,240 JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of CYP7B1 mRNA CTD PMID:18579281 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Ddc dopa decarboxylase increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of DDC mRNA CTD PMID:18579281 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of EEPD1 mRNA CTD PMID:18579281 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of and results in increased activity of EPHX2 protein CTD PMID:3032197 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 2,4,5-Trichlorophenoxyacetic Acid binds to and results in decreased activity of ESR1 protein CTD PMID:16626760 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Far1 fatty acyl CoA reductase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FAR1 mRNA CTD PMID:18579281 NCBI chr 1:178,351,674...178,412,838
Ensembl chr 1:178,351,680...178,431,395
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FKBP5 mRNA CTD PMID:18579281 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of FMO2 mRNA CTD PMID:18579281 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G G0s2 G0/G1switch 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of G0S2 mRNA CTD PMID:18579281 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GBF1 mRNA CTD PMID:18579281 NCBI chr 1:265,904,616...266,033,107
Ensembl chr 1:265,904,566...266,033,156
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC mRNA
2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC; 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GCLC mRNA
CTD PMID:10377250, PMID:16426233 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GDE1 mRNA CTD PMID:18579281 NCBI chr 1:188,367,550...188,407,125
Ensembl chr 1:188,394,814...188,407,132
JBrowse link
G Gfra1 GDNF family receptor alpha 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GFRA1 mRNA CTD PMID:18579281 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Git2 GIT ArfGAP 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GIT2 mRNA CTD PMID:18579281 NCBI chr12:47,590,110...47,630,991
Ensembl chr12:47,590,154...47,631,119
JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GMPPB mRNA CTD PMID:18579281 NCBI chr 8:116,826,251...116,856,159
Ensembl chr 8:116,826,680...116,856,159
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GOT1 mRNA CTD PMID:18579281 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GPM6A mRNA CTD PMID:18579281 NCBI chr16:39,367,697...39,719,292
Ensembl chr16:39,367,692...39,719,187
JBrowse link
G Gpr12 G protein-coupled receptor 12 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GPR12 mRNA CTD PMID:18579281 NCBI chr12:10,253,710...10,257,135
Ensembl chr12:10,254,951...10,257,130
JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of GPR85 mRNA CTD PMID:18579281 NCBI chr 4:40,377,705...40,387,147
Ensembl chr 4:40,381,685...40,385,349
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HAPLN1 mRNA CTD PMID:18579281 NCBI chr 2:18,354,542...18,419,077
Ensembl chr 2:18,354,542...18,419,071
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HMOX1 mRNA CTD PMID:18579281 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPA8 mRNA CTD PMID:18579281 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPB1 mRNA CTD PMID:18579281 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of HSPH1 mRNA CTD PMID:18579281 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IDO2 mRNA CTD PMID:18579281 NCBI chr16:72,232,852...72,291,227
Ensembl chr16:72,268,943...72,289,156
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IHH mRNA CTD PMID:18579281 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of IKBKE mRNA CTD PMID:18579281 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of IL1R1 mRNA CTD PMID:18579281 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Insc INSC, spindle orientation adaptor protein increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of INSC mRNA CTD PMID:18579281 NCBI chr 1:184,299,200...184,407,487
Ensembl chr 1:184,299,250...184,407,480
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of KLF5 mRNA CTD PMID:18579281 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Limch1 LIM and calponin homology domains 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LIMCH1 mRNA CTD PMID:18579281 NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LMCD1 mRNA CTD PMID:18579281 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G LOC102547963 leucine-rich repeat and transmembrane domain-containing protein 1-like increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LRTM1 mRNA CTD PMID:18579281 NCBI chr16:5,078,506...5,089,888
Ensembl chr16:5,082,239...5,087,844
JBrowse link
G LOC103690086 uncharacterized LOC103690086 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of GBP9 mRNA CTD PMID:18579281 NCBI chr14:5,642,357...5,646,406 JBrowse link
G Lpar4 lysophosphatidic acid receptor 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LPAR4 mRNA CTD PMID:18579281 NCBI chr  X:78,042,859...78,056,347
Ensembl chr  X:78,042,859...78,056,347
JBrowse link
G Lpin1 lipin 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of LPIN1 mRNA CTD PMID:18579281 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of LRTM1 mRNA CTD PMID:18579281 NCBI chr16:4,993,728...5,005,110
Ensembl chr16:4,997,461...5,003,066
JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MATK mRNA CTD PMID:18579281 NCBI chr 7:11,325,246...11,334,311
Ensembl chr 7:11,325,254...11,330,278
JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MPDZ mRNA CTD PMID:18579281 NCBI chr 5:99,413,184...99,566,356
Ensembl chr 5:99,413,187...99,566,318
JBrowse link
G Mt1 metallothionein 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT1 mRNA CTD PMID:18579281 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt4 metallothionein 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT4 mRNA CTD PMID:18579281 NCBI chr19:11,339,767...11,341,863
Ensembl chr19:11,339,767...11,341,863
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MVD mRNA CTD PMID:18579281 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Mybph myosin binding protein H increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of MYBPH mRNA CTD PMID:18579281 NCBI chr13:51,034,228...51,041,903
Ensembl chr13:51,034,256...51,041,902
JBrowse link
G Ndrg4 NDRG family member 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NDRG4 mRNA CTD PMID:18579281 NCBI chr19:9,766,439...9,802,396
Ensembl chr19:9,766,439...9,801,942
JBrowse link
G Nip7 nucleolar pre-rRNA processing protein NIP7 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NIP7 mRNA CTD PMID:18579281 NCBI chr19:39,257,586...39,259,728
Ensembl chr19:39,257,586...39,259,728
JBrowse link
G Nrg4 neuregulin 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of NRG4 mRNA CTD PMID:18579281 NCBI chr 8:59,782,789...59,849,433
Ensembl chr 8:59,782,974...59,849,490
JBrowse link
G Ogn osteoglycin decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of OGN mRNA CTD PMID:18579281 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359
JBrowse link
G Olr346 olfactory receptor 346 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of OLFR1451 mRNA CTD PMID:18579281 NCBI chr 1:229,849,892...229,850,818
Ensembl chr 1:229,849,892...229,850,818
JBrowse link
G Pdzd3 PDZ domain containing 3 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PDZD3 mRNA CTD PMID:18579281 NCBI chr 8:48,577,905...48,582,353
Ensembl chr 8:48,577,952...48,582,353
JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PFKP mRNA CTD PMID:18579281 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Plin4 perilipin 4 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PLIN4 mRNA CTD PMID:18579281 NCBI chr 9:10,963,494...10,972,360
Ensembl chr 9:10,963,723...10,971,277
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of POR mRNA CTD PMID:18579281 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppfibp1 PPFIA binding protein 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPFIBP1 mRNA CTD PMID:18579281 NCBI chr 4:181,285,179...181,428,157
Ensembl chr 4:181,286,455...181,428,157
JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPP1R3A mRNA CTD PMID:18579281 NCBI chr 4:41,171,486...41,212,116
Ensembl chr 4:41,171,486...41,212,072
JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PPP1R3G mRNA CTD PMID:18579281 NCBI chr17:29,566,032...29,570,294
Ensembl chr17:29,567,404...29,568,447
JBrowse link
G Prok1 prokineticin 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of PROK1 mRNA CTD PMID:18579281 NCBI chr 2:209,986,503...209,994,438
Ensembl chr 2:209,987,992...209,993,250
JBrowse link
G Prr9 proline rich 9 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PRR9 mRNA CTD PMID:18579281 NCBI chr 2:192,025,457...192,036,073
Ensembl chr 2:192,025,875...192,027,225
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of PTP4A1 mRNA CTD PMID:18579281 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Retreg1 reticulophagy regulator 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of RETREG1 mRNA CTD PMID:18579281 NCBI chr 2:78,391,921...78,401,569
Ensembl chr 2:78,391,921...78,399,987
JBrowse link
G Rprd1a regulation of nuclear pre-mRNA domain containing 1A decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of RPRD1A mRNA CTD PMID:18579281 NCBI chr18:16,450,160...16,497,913
Ensembl chr18:16,453,369...16,497,886
JBrowse link
G Selenop selenoprotein P decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SELENOP mRNA CTD PMID:18579281 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Sema3c semaphorin 3C decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SEMA3C mRNA CTD PMID:18579281 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SGK2 mRNA CTD PMID:18579281 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
JBrowse link
G Slc24a2 solute carrier family 24 member 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SLC24A2 mRNA CTD PMID:18579281 NCBI chr 5:105,336,287...105,579,959
Ensembl chr 5:105,336,262...105,582,375
JBrowse link
G Slc25a32 solute carrier family 25 member 32 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SLC25A32 mRNA CTD PMID:18579281 NCBI chr 7:77,983,885...78,005,058
Ensembl chr 7:77,987,212...78,004,975
JBrowse link
G Slc66a1 solute carrier family 66 member 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SLC66A1 mRNA CTD PMID:18579281 NCBI chr 5:157,744,945...157,759,370
Ensembl chr 5:157,745,490...157,759,322
JBrowse link
G Slc6a15 solute carrier family 6 member 15 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of SLC6A15 mRNA CTD PMID:18579281 NCBI chr 7:45,328,207...45,381,920
Ensembl chr 7:45,328,105...45,382,229
JBrowse link
G Snx7 sorting nexin 7 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SNX7 mRNA CTD PMID:18579281 NCBI chr 2:221,015,302...221,099,810
Ensembl chr 2:221,015,310...221,099,738
JBrowse link
G Spon2 spondin 2 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SPON2 mRNA CTD PMID:18579281 NCBI chr14:82,815,158...82,824,529
Ensembl chr14:82,818,663...82,824,599
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SREBF1 mRNA CTD PMID:18579281 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Svil supervillin increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of SVIL mRNA CTD PMID:18579281 NCBI chr17:55,230,298...55,425,967
Ensembl chr17:55,230,298...55,346,279
JBrowse link
G Tacc2 transforming, acidic coiled-coil containing protein 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TACC2 mRNA CTD PMID:18579281 NCBI chr 1:201,140,264...201,329,612
Ensembl chr 1:201,055,644...201,329,622
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TBC1D8 mRNA CTD PMID:18579281 NCBI chr 9:46,090,613...46,206,672
Ensembl chr 9:46,090,019...46,206,605
JBrowse link
G Tcea2 transcription elongation factor A2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TCEA2 mRNA CTD PMID:18579281 NCBI chr 3:177,187,686...177,195,898
Ensembl chr 3:177,188,044...177,195,894
JBrowse link
G Thra thyroid hormone receptor alpha increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of THRA mRNA CTD PMID:18579281 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4,5-Trichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tom1l2 target of myb1 like 2 membrane trafficking protein decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TOM1L2 mRNA CTD PMID:18579281 NCBI chr10:46,599,392...46,720,921
Ensembl chr10:46,602,231...46,720,910
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of TRIB3 mRNA CTD PMID:18579281 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tril TLR4 interactor with leucine-rich repeats decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of TRIL mRNA CTD PMID:18579281 NCBI chr 4:83,967,695...83,972,540
Ensembl chr 4:83,967,696...83,972,540
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of TSC22D1 mRNA CTD PMID:18579281 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of UGT2A3 mRNA CTD PMID:18579281 NCBI chr14:22,251,507...22,267,899
Ensembl chr14:22,192,970...22,619,968
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of USP2 mRNA CTD PMID:18579281 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of VCAM1 mRNA CTD PMID:18579281 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of VEPH1 mRNA CTD PMID:18579281 NCBI chr 2:157,869,383...158,156,266
Ensembl chr 2:157,869,392...158,156,444
JBrowse link
G Wars2 tryptophanyl tRNA synthetase 2 (mitochondrial) increases expression ISO 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of WARS2 mRNA CTD PMID:18579281 NCBI chr 2:201,170,363...201,256,115
Ensembl chr 2:201,172,312...201,255,703
JBrowse link
(4-chloro-2-methylphenoxy)acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcnka chloride voltage-gated channel Ka decreases activity EXP 2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKA protein CTD PMID:15167890 NCBI chr 5:159,931,497...159,946,483
Ensembl chr 5:159,931,511...159,946,446
JBrowse link
G Clcnkb chloride voltage-gated channel Kb decreases activity EXP 2-Methyl-4-chlorophenoxyacetic Acid analog results in decreased activity of CLCNKB protein CTD PMID:15167890 NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676
JBrowse link
G Slc1a2 solute carrier family 1 member 2 affects expression EXP 2-Methyl-4-chlorophenoxyacetic Acid affects the expression of SLC1A2 protein CTD PMID:16019039 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2-Methyl-4-chlorophenoxyacetic Acid results in increased expression of TNF protein CTD PMID:10883730 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
2,4-D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Alb albumin affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to ALB protein CTD PMID:9877224, PMID:11451446 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ar androgen receptor multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Androgens binds to AR protein]; 2,4-Dichlorophenoxyacetic Acid promotes the reaction [Dihydrotestosterone results in increased localization of and results in increased activity of AR protein] CTD PMID:16107550 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Ccdc120 coiled-coil domain containing 120 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CCDC120 mRNA CTD PMID:15878651 NCBI chr  X:15,610,230...15,616,727
Ensembl chr  X:15,598,652...15,617,665
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL11 protein CTD PMID:19467290 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL2 protein CTD PMID:19467290 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of CCL4 protein CTD PMID:19467290 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Cldn1 claudin 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLDN1 protein CTD PMID:28699141 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CLK1 mRNA CTD PMID:15878651 NCBI chr 9:65,296,777...65,308,017
Ensembl chr 9:65,296,778...65,307,995
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CNP protein CTD PMID:18460445 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Crat carnitine O-acetyltransferase increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of CRAT protein CTD PMID:1755024 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression ISO 2,4-Dichlorophenoxyacetic Acid affects the expression of CYP17A1 mRNA CTD PMID:26838045 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A1 mRNA CTD PMID:10910964 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A2 mRNA CTD PMID:10910964 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1B1 mRNA CTD PMID:10910964 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dbh dopamine beta-hydroxylase decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of DBH protein CTD PMID:16931444 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dclre1c DNA cross-link repair 1C increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DCLRE1C mRNA CTD PMID:15878651 NCBI chr17:78,782,512...78,812,140
Ensembl chr17:78,783,437...78,812,111
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of DDB2 mRNA CTD PMID:15878651 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity ISO 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX2 protein CTD PMID:1755024, PMID:3032197 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTH1 mRNA CTD PMID:15878651 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of FTL mRNA CTD PMID:15878651 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of GFAP mRNA CTD PMID:22954530 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCR CTD PMID:26838045 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of HMGCS1 CTD PMID:26838045 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Ifng interferon gamma increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IFNG CTD PMID:20728597 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of IL1RL1 mRNA CTD PMID:15878651 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il2 interleukin 2 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2 CTD PMID:20728597 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL2RA CTD PMID:20728597 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il4 interleukin 4 increases expression
increases secretion
ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL4 protein
2,4-Dichlorophenoxyacetic Acid results in increased secretion of IL4 protein
CTD PMID:19467290 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL5 protein CTD PMID:19467290 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of IL6 protein CTD PMID:19467290 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ldha lactate dehydrogenase A decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of LDHA protein CTD PMID:23538319 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Mbp myelin basic protein decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of MBP protein CTD PMID:18460445 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO 2,4-Dichlorophenoxyacetic Acid results in decreased methylation of MYC promoter CTD PMID:11857776 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ocln occludin decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of OCLN mRNA CTD PMID:28699141 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide decreases secretion EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of OXT protein CTD PMID:20122984 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of PCNA mRNA CTD PMID:15878651 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PFKM protein CTD PMID:23538319 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance ISO PPARA protein results in increased susceptibility to 2,4-Dichlorophenoxyacetic Acid CTD PMID:26838045 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Prl prolactin decreases secretion EXP 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of PRL protein CTD PMID:20122984 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of PTGER3 mRNA CTD PMID:15878651 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Slc16a3 solute carrier family 16 member 3 decreases expression
increases expression
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC16A3 mRNA
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC16A3 mRNA
CTD PMID:23538319 NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Potassium promotes the reaction [SLC22A12 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid] CTD PMID:15284287 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:221,327,608...221,344,367
Ensembl chr 1:221,328,711...221,343,889
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake
multiple interactions
EXP
ISO
SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid
p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased uptake of 2,4-Dichlorophenoxyacetic Acid]
CTD PMID:16857889, PMID:17255469 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression
increases expression
EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of SLC2A3 protein
2,4-Dichlorophenoxyacetic Acid results in increased expression of SLC2A3 mRNA
CTD PMID:23538319 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Th tyrosine hydroxylase increases expression EXP 2,4-Dichlorophenoxyacetic Acid results in increased expression of TH protein CTD PMID:16931444 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO 2,4-Dichlorophenoxyacetic Acid binds to THRB protein CTD PMID:27410513 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 mRNA; 2,4-Dichlorophenoxyacetic Acid results in decreased expression of TJP1 protein CTD PMID:28699141 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of TNF CTD PMID:20728597 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Usp19 ubiquitin specific peptidase 19 increases expression ISO 2,4-Dichlorophenoxyacetic Acid results in increased expression of USP19 mRNA CTD PMID:15878651 NCBI chr 8:117,280,690...117,291,729
Ensembl chr 8:117,280,705...117,291,351
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO 2,4-Dichlorophenoxyacetic Acid results in decreased expression of VEGFA mRNA CTD PMID:15878651 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        aetiopathogenetic role 18936
          allergen 16919
            phenoxyacetic acid 158
              chlorophenoxyacetic acid + 158
              phenoxyacetyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        hydroxy carboxylic acid 3602
                                          hydroxy monocarboxylic acid 3602
                                            2-hydroxy monocarboxylic acid 2915
                                              glycolic acid 162
                                                phenoxyacetic acid 158
                                                  chlorophenoxyacetic acid + 158
                                                  phenoxyacetyl-CoA 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.