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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Potassium 2,6-dihydroxytriazinecarboxylate
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Accession:CHEBI:80230 term browser browse the term
Definition:An organic molecular entity that has formula C4H2KN3O4.
Synonyms:related_synonym: Formula=C4H2KN3O4;   InChI=1S/C4H3N3O4.K/c8-2(9)1-5-3(10)7-4(11)6-1;/h(H,8,9)(H2,5,6,7,10,11);/q;+1/p-1;   InChIKey=IAPCTXZQXAVYNG-UHFFFAOYSA-M;   Oteracil potassium;   Potassium oxonate;   SMILES=[K+].[O-]C(=O)c1nc(=O)[nH]c(=O)[nH]1
 alt_id: MESH:C489337
 xref: CAS:2207-75-2;   KEGG:C15997
 xref_mesh: MESH:C489337


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Potassium 2,6-dihydroxytriazinecarboxylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
ISO 4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; Allopurinol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; mulberroside A inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; resveratrol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein] CTD PMID:20868668 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:20868668 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression
multiple interactions
ISO potassium oxonate results in decreased expression of SLC22A1 mRNA; potassium oxonate results in decreased expression of SLC22A1 protein
Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; mulberroside A inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]; resveratrol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein]
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions
increases expression
ISO 4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Allopurinol inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; mulberroside A inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; pterostilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]
potassium oxonate results in increased expression of SLC22A12 mRNA; potassium oxonate results in increased expression of SLC22A12 protein
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression
multiple interactions
ISO potassium oxonate results in decreased expression of SLC22A2 mRNA; potassium oxonate results in decreased expression of SLC22A2 protein
Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein]
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a4 solute carrier family 22 member 4 decreases expression
multiple interactions
ISO potassium oxonate results in decreased expression of SLC22A4 mRNA; potassium oxonate results in decreased expression of SLC22A4 protein
Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]; mulberroside A inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]; polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein]
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr10:39,334,972...39,373,508 JBrowse link
G Slc22a5 solute carrier family 22 member 5 decreases expression
multiple interactions
ISO potassium oxonate results in decreased expression of SLC22A5 mRNA; potassium oxonate results in decreased expression of SLC22A5 protein
Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]; mulberroside A inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]; polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein]
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases expression
multiple interactions
ISO potassium oxonate results in decreased expression of SLC22A6 mRNA; potassium oxonate results in decreased expression of SLC22A6 protein
Allopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; mulberroside A inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]; resveratrol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc2a9 solute carrier family 2 member 9 multiple interactions
increases expression
ISO Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]; mulberroside A inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]; polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]; resveratrol inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein]
potassium oxonate results in increased expression of SLC2A9 mRNA; potassium oxonate results in increased expression of SLC2A9 protein
CTD PMID:21909718, PMID:22865646, PMID:22967667 NCBI chr14:77,067,537...77,192,702
Ensembl chr14:77,067,503...77,192,702
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] CTD PMID:20868668 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Umod uromodulin multiple interactions
affects expression
increases expression
ISO 4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of UMOD protein]; Allopurinol inhibits the reaction [potassium oxonate affects the expression of UMOD protein]; Allopurinol inhibits the reaction [potassium oxonate results in increased expression of UMOD mRNA]; mulberroside A inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein]; polydatin inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein]; potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein; Probenecid inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein]; pterostilbene inhibits the reaction [potassium oxonate results in increased expression of UMOD protein]; Quercetin inhibits the reaction [potassium oxonate affects the expression of UMOD protein]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of UMOD mRNA]; Stilbenes analog inhibits the reaction [potassium oxonate results in increased expression of UMOD protein] CTD PMID:21909718, PMID:22865646 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Potassium 2,6-dihydroxytriazinecarboxylate 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Potassium 2,6-dihydroxytriazinecarboxylate 12
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.