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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:GW 4064
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Accession:CHEBI:79997 term browser browse the term
Definition:A stilbenoid that has formula C28H22Cl3NO4.
Synonyms:exact_synonym: GW4064
 related_synonym: Formula=C28H22Cl3NO4;   InChI=1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)/b10-9+;   InChIKey=BYTNEISLBIENSA-MDZDMXLPSA-N;   SMILES=CC(C)c1onc(c1COc1ccc(\\C=C\\c2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl
 xref: CAS:278779-30-9;   KEGG:C15635
 xref_mesh: MESH:C412815
 xref: PDBeChem:064


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GW 4064 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor increases expression ISO GW 4064 results in increased expression of A1CF mRNA CTD PMID:26655953 NCBI chr 1:250,426,027...250,514,245
Ensembl chr 1:250,426,158...250,514,866
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO GW 4064 results in decreased expression of ABCA1 mRNA CTD PMID:31437187 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression
multiple interactions
ISO
EXP
GW 4064 results in increased expression of ABCB11 mRNA
GW 4064 inhibits the reaction [17alpha-ethynylestradiol decreases expression of Abcb11 mRNA in primary hepatocytes]
GW 4064 increases expression of Abcb11 mRNA in primary hepatocytes
[pregna-4,17-diene-3,16-dione co-treated with GW 4064] results in increased expression of ABCB11 mRNA; alpha-Linolenic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; Arachidonic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; Docosahexaenoic Acids promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; LG 100268 inhibits the reaction [GW 4064 results in increased expression of ABCB11 mRNA]
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of ABCB11 mRNA; ATP7B protein affects the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; epiallopregnanolone sulfate inhibits the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; epiallopregnanolone sulfate inhibits the reaction [GW 4064 results in increased expression of ABCB11 protein]; GW 4064 inhibits the reaction [ATP7B gene mutant form results in decreased expression of ABCB11 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; NR1H4 protein promotes the reaction [GW 4064 results in increased expression of ABCB11 protein]
GW 4064 results in increased expression of ABCB11 mRNA; GW 4064 results in increased expression of ABCB11 protein
GW 4064 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA]
CTD PMID:12519787 PMID:12525500 PMID:14623915 PMID:15307955 PMID:15644430 PMID:15911693 PMID:22178739 PMID:22540009 PMID:22918042 PMID:22961653 PMID:26241054 PMID:27090119 PMID:27609522, PMID:27090119, PMID:27090119 RGD:15090804, RGD:15090804 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
multiple interactions
ISO
EXP
GW 4064 results in increased expression of ABCB4 mRNA
[[GW 4064 binds to and results in increased activity of NR1H4 protein] which binds to ABCB4 promoter] which results in increased expression of ABCB4 mRNA
CTD PMID:14527955 PMID:14623915 PMID:15644430 PMID:27609522 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
EXP GW 4064 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]
GW 4064 inhibits the reaction [17alpha-ethynylestradiol decreases expression of Abcc2 mRNA in primary hepatocytes]
GW 4064 increases expression of Abcc2 mRNA in primary hepatocytes
GW 4064 results in increased expression of ABCC2 mRNA
CTD PMID:14623915 PMID:15644430 PMID:27090119, PMID:27090119, PMID:27090119 RGD:15090804, RGD:15090804 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO GW 4064 results in increased expression of ABCC3 mRNA CTD PMID:27609522 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO GW 4064 results in increased expression of ABCC6 mRNA CTD PMID:26655953 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions
increases expression
ISO FGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA] CTD PMID:22918042 PMID:30996006 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 multiple interactions
increases expression
ISO FGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG8 mRNA] CTD PMID:30996006 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abhd15 abhydrolase domain containing 15 increases expression ISO GW 4064 results in increased expression of ABHD15 mRNA CTD PMID:26655953 NCBI chr10:62,643,453...62,648,844
Ensembl chr10:62,643,453...62,648,844
JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO GW 4064 results in decreased expression of ABI3BP mRNA CTD PMID:26655953 NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAA2 mRNA CTD PMID:30611723 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACA mRNA CTD PMID:30611723 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACB mRNA CTD PMID:30611723 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA
GW 4064 results in decreased expression of ACADL mRNA
CTD PMID:30611723 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA
GW 4064 results in decreased expression of ACADM mRNA
CTD PMID:30611723 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions
increases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADS mRNA
GW 4064 results in increased expression of ACADS mRNA
CTD PMID:30611723 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADVL mRNA CTD PMID:30611723 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT1 mRNA
GW 4064 results in decreased expression of ACAT1 mRNA
CTD PMID:30611723 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression
multiple interactions
ISO GW 4064 results in increased expression of ACAT2 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT2 mRNA
CTD PMID:26655953 PMID:30611723 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ace angiotensin I converting enzyme increases expression ISO GW 4064 results in increased expression of ACE mRNA CTD PMID:26655953 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression ISO GW 4064 results in increased expression of ACE2 mRNA CTD PMID:26655953 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACLY mRNA CTD PMID:30611723 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT1 mRNA CTD PMID:30611723 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot12 acyl-CoA thioesterase 12 increases expression
multiple interactions
decreases expression
ISO GW 4064 results in increased expression of ACOT12 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT12 mRNA
GW 4064 results in decreased expression of ACOT12 mRNA
CTD PMID:26655953 PMID:30611723 NCBI chr 2:20,857,056...20,901,656
Ensembl chr 2:20,857,202...20,901,659
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO GW 4064 results in increased expression of ACOT3 mRNA CTD PMID:26655953 NCBI chr 6:107,531,508...107,537,446
Ensembl chr 6:107,531,528...107,536,789
JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression
multiple interactions
ISO GW 4064 results in increased expression of ACOT4 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT4 mRNA
CTD PMID:26655953 PMID:30611723 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Acot6 acyl-CoA thioesterase 6 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of ACOT6 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA
CTD PMID:30611723 NCBI chr 6:107,581,357...107,590,431
Ensembl chr 6:107,581,608...107,590,373
JBrowse link
G Acot7 acyl-CoA thioesterase 7 increases expression
multiple interactions
ISO GW 4064 results in increased expression of ACOT7 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT7 mRNA
CTD PMID:30611723 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219
JBrowse link
G Acot8 acyl-CoA thioesterase 8 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA CTD PMID:30611723 NCBI chr 3:161,260,837...161,272,495
Ensembl chr 3:161,259,735...161,272,460
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA
GW 4064 results in decreased expression of ACOX1 mRNA
CTD PMID:30611723 PMID:31437187 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA
GW 4064 results in decreased expression of ACOX2 mRNA
CTD PMID:30611723 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression
multiple interactions
ISO GW 4064 results in increased expression of ACSL3 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL3 mRNA
CTD PMID:30611723 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL4 mRNA CTD PMID:30611723 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO GW 4064 results in increased expression of ACSL5 mRNA CTD PMID:30611723 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 increases expression ISO GW 4064 results in increased expression of ACSM1 mRNA CTD PMID:26655953 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Actg1 actin, gamma 1 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to ACTG1 gene] CTD PMID:20091679 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 increases expression ISO GW 4064 results in increased expression of ADAMTS15 mRNA CTD PMID:26655953 NCBI chr 8:31,977,001...32,000,378
Ensembl chr 8:31,977,001...32,000,378
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression ISO GW 4064 results in decreased expression of ADAMTS5 mRNA CTD PMID:26655953 NCBI chr11:25,411,174...25,456,639
Ensembl chr11:25,410,975...25,456,836
JBrowse link
G Adgra1 adhesion G protein-coupled receptor A1 decreases expression ISO GW 4064 results in decreased expression of ADGRA1 mRNA CTD PMID:26655953 NCBI chr 1:212,170,190...212,213,156
Ensembl chr 1:212,181,374...212,211,578
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression ISO GW 4064 results in decreased expression of ADGRE1 mRNA CTD PMID:23371517 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865
JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 decreases expression ISO GW 4064 results in decreased expression of ADGRF4 mRNA CTD PMID:26655953 NCBI chr 9:20,951,249...20,982,493
Ensembl chr 9:20,951,260...20,982,487
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO GW 4064 results in increased expression of ADH7 mRNA CTD PMID:26655953 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 increases expression ISO GW 4064 results in increased expression of ADHFE1 mRNA CTD PMID:26655953 NCBI chr 5:9,403,194...9,429,783
Ensembl chr 5:9,403,196...9,429,859
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein increases expression ISO GW 4064 results in increased expression of ADTRP mRNA CTD PMID:26655953 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 multiple interactions
increases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA
GW 4064 results in increased expression of AGPAT1 mRNA
CTD PMID:30611723 NCBI chr20:4,369,399...4,378,272
Ensembl chr20:4,369,178...4,378,269
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression ISO GW 4064 results in increased expression of AGPAT2 mRNA CTD PMID:30611723 NCBI chr 3:4,044,741...4,055,384
Ensembl chr 3:4,044,542...4,055,806
JBrowse link
G Ahcyl2 adenosylhomocysteinase-like 2 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of AHCYL2 mRNA
NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of AHCYL2 mRNA]
CTD PMID:29416063 NCBI chr 4:57,050,241...57,199,870
Ensembl chr 4:57,050,214...57,199,900
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression ISO GW 4064 results in increased expression of AKR1B7 mRNA CTD PMID:26655953 NCBI chr 4:61,850,256...61,879,733
Ensembl chr 4:61,850,348...61,862,526
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO GW 4064 results in decreased expression of ALDH2 protein CTD PMID:23178280 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO GW 4064 results in increased expression of ALPPL2 mRNA CTD PMID:26655953 NCBI chr 9:94,164,667...94,184,972
Ensembl chr 9:94,178,221...94,181,010
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO GW 4064 results in increased expression of ALPL mRNA CTD PMID:26655953 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Ang angiogenin increases expression ISO GW 4064 results in increased expression of ANG mRNA CTD PMID:26655953 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 increases expression ISO GW 4064 results in increased expression of ANG2 mRNA CTD PMID:26655953 NCBI chr15:28,103,688...28,121,494
Ensembl chr15:28,103,703...28,104,206
JBrowse link
G Ankrd34b ankyrin repeat domain 34B decreases expression ISO GW 4064 results in decreased expression of ANKRD34B mRNA CTD PMID:26655953 NCBI chr 2:22,000,106...22,016,764
Ensembl chr 2:22,000,106...22,016,030
JBrowse link
G Ankrd65 ankyrin repeat domain 65 increases expression ISO GW 4064 results in increased expression of ANKRD65 mRNA CTD PMID:26655953 NCBI chr 5:173,237,642...173,239,899
Ensembl chr 5:173,237,642...173,239,899
JBrowse link
G Anpep alanyl aminopeptidase, membrane increases expression ISO GW 4064 results in increased expression of ANPEP mRNA CTD PMID:26655953 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Aoah acyloxyacyl hydrolase increases expression ISO GW 4064 results in increased expression of AOAH mRNA CTD PMID:26655953 NCBI chr17:45,872,414...46,115,026
Ensembl chr17:45,872,414...46,115,004
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
multiple interactions
increases expression
ISO GW 4064 results in decreased expression of APOA1 protein
bisphenol A inhibits the reaction [GW 4064 results in increased expression of APOA1 mRNA]; GW 4064 inhibits the reaction [bisphenol A results in increased expression of APOA1 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of APOA1 mRNA]; Stigmasterol promotes the reaction [GW 4064 results in increased expression of APOA1 mRNA]
CTD PMID:19445040 PMID:30245210 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa5 apolipoprotein A5 multiple interactions
increases expression
ISO [GW 4064 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA
GW 4064 results in increased expression of APOA5 mRNA
CTD PMID:30611723 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Apob apolipoprotein B increases expression
decreases expression
multiple interactions
ISO GW 4064 results in increased expression of APOB mRNA
GW 4064 results in decreased expression of APOB mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOB mRNA
CTD PMID:26655953 PMID:30611723 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 increases expression ISO GW 4064 results in increased expression of APOBEC2 mRNA CTD PMID:26655953 NCBI chr 9:14,529,218...14,542,731
Ensembl chr 9:14,529,218...14,542,731
JBrowse link
G Apoc4 apolipoprotein C4 increases expression
multiple interactions
ISO GW 4064 results in increased expression of APOC4 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA
CTD PMID:30611723 NCBI chr 1:80,595,339...80,599,525
Ensembl chr 1:80,595,326...80,599,572
JBrowse link
G Apoe apolipoprotein E multiple interactions
increases expression
ISO GW 4064 promotes the reaction [NR1H4 protein binds to APOE gene]
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOE mRNA
GW 4064 results in increased expression of APOE mRNA
CTD PMID:20091679 PMID:26655953 PMID:30611723 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apol9a apolipoprotein L 9a decreases expression ISO GW 4064 results in decreased expression of APOL9A mRNA CTD PMID:26655953 NCBI chr 7:118,927,013...118,933,778
Ensembl chr 7:118,927,008...118,933,812
JBrowse link
G Apom apolipoprotein M increases expression ISO GW 4064 results in increased expression of APOM mRNA CTD PMID:26655953 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO GW 4064 results in increased expression of AQP1 mRNA CTD PMID:26655953 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arg2 arginase 2 decreases expression ISO GW 4064 results in decreased expression of ARG2 mRNA CTD PMID:26655953 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO GW 4064 results in increased expression of ASB2 mRNA CTD PMID:26655953 NCBI chr 6:127,212,325...127,248,451
Ensembl chr 6:127,212,273...127,248,372
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO GW 4064 results in decreased expression of ASGR1 mRNA CTD PMID:31437187 NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO GW 4064 results in increased expression of ASS1 mRNA CTD PMID:26655953 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Astn1 astrotactin 1 increases expression ISO GW 4064 results in increased expression of ASTN1 mRNA CTD PMID:26655953 NCBI chr13:76,054,965...76,370,674
Ensembl chr13:76,055,410...76,370,674
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA] CTD PMID:28223344 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 increases expression ISO GW 4064 results in increased expression of ATP1A4 mRNA CTD PMID:26655953 NCBI chr13:90,605,792...90,642,032
Ensembl chr13:90,605,794...90,641,772
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 decreases expression ISO GW 4064 results in decreased expression of ATP6V0D2 mRNA CTD PMID:26655953 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions ISO ATP7B protein affects the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; ATP7B protein affects the reaction [GW 4064 results in increased expression of NR0B2 mRNA]; GW 4064 inhibits the reaction [ATP7B gene mutant form results in decreased expression of ABCB11 mRNA]; GW 4064 inhibits the reaction [ATP7B gene mutant form results in decreased expression of NR0B2 mRNA] CTD PMID:26241054 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G B3gat2 beta-1,3-glucuronyltransferase 2 increases expression ISO GW 4064 results in increased expression of B3GAT2 mRNA CTD PMID:26655953 NCBI chr 9:29,984,077...30,068,649
Ensembl chr 9:29,984,077...30,068,649
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression ISO GW 4064 results in increased expression of BAAT mRNA CTD PMID:26655953 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to BCCIP gene] CTD PMID:20091679 NCBI chr 1:205,777,474...205,789,887
Ensembl chr 1:205,777,130...205,790,175
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO GW 4064 results in increased expression of BUB1 mRNA CTD PMID:31437187 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO GW 4064 results in increased expression of BUB1B mRNA CTD PMID:31437187 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C1qtnf3 C1q and TNF related 3 increases expression ISO GW 4064 results in increased expression of C1QTNF3 mRNA CTD PMID:26655953 NCBI chr 2:60,920,160...60,942,586
Ensembl chr 2:60,920,257...60,942,500
JBrowse link
G C3 complement C3 increases expression ISO GW 4064 results in increased expression of C3 mRNA CTD PMID:26655953 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cabp4 calcium binding protein 4 increases expression ISO GW 4064 results in increased expression of CABP4 mRNA CTD PMID:26655953 NCBI chr 1:219,383,452...219,388,009
Ensembl chr 1:219,383,452...219,388,009
JBrowse link
G Cadps2 calcium dependent secretion activator 2 increases expression ISO GW 4064 results in increased expression of CADPS2 mRNA CTD PMID:26655953 NCBI chr 4:50,326,447...50,861,161
Ensembl chr 4:50,326,442...50,860,756
JBrowse link
G Calcr calcitonin receptor decreases expression ISO GW 4064 results in decreased expression of CALCR mRNA CTD PMID:26655953 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase IG increases expression ISO GW 4064 results in increased expression of CAMK1G mRNA CTD PMID:26655953 NCBI chr13:112,075,689...112,099,472
Ensembl chr13:112,075,690...112,099,336
JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to CAPRIN1 gene] CTD PMID:20091679 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Casp12 caspase 12 decreases expression ISO GW 4064 results in decreased expression of CASP12 mRNA CTD PMID:26655953 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Cckar cholecystokinin A receptor increases expression ISO GW 4064 results in increased expression of CCKAR mRNA CTD PMID:26655953 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases expression
ISO GW 4064 results in decreased expression of CCL2 mRNA
GW 4064 results in increased expression of CCL2 mRNA
CTD PMID:23371517 PMID:26655953 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO GW 4064 results in increased expression of CCL7 mRNA CTD PMID:26655953 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccna2 cyclin A2 increases expression ISO GW 4064 results in increased expression of CCNA2 mRNA CTD PMID:31437187 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO GW 4064 results in increased expression of CCNB1 mRNA CTD PMID:31437187 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO GW 4064 results in increased expression of CCND1 mRNA CTD PMID:31437187 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression ISO GW 4064 results in increased expression of CCNE1 mRNA CTD PMID:31437187 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 increases expression ISO GW 4064 results in increased expression of CCNE2 mRNA CTD PMID:31437187 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cd36 CD36 molecule multiple interactions
decreases expression
ISO GW 4064 inhibits the reaction [Oleic Acid results in increased expression of CD36 protein]
[GW 4064 co-treated with Oleic Acid] results in increased expression of CD36 mRNA
GW 4064 results in decreased expression of CD36 mRNA; GW 4064 results in decreased expression of CD36 protein
CTD PMID:23371517 PMID:30611723 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd68 Cd68 molecule decreases expression ISO GW 4064 results in decreased expression of CD68 mRNA CTD PMID:23371517 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd72 Cd72 molecule increases expression ISO GW 4064 results in increased expression of CD72 mRNA CTD PMID:26655953 NCBI chr 5:58,943,021...58,950,373
Ensembl chr 5:58,943,027...58,950,373
JBrowse link
G Cd83 CD83 molecule increases expression ISO GW 4064 results in increased expression of CD83 mRNA CTD PMID:26655953 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO GW 4064 results in increased expression of CDC20 mRNA CTD PMID:31437187 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25c cell division cycle 25C increases expression ISO GW 4064 results in increased expression of CDC25C mRNA CTD PMID:31437187 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO GW 4064 results in increased expression of CDC45 mRNA CTD PMID:31437187 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO GW 4064 results in increased expression of CDC6 mRNA CTD PMID:31437187 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdc7 cell division cycle 7 increases expression ISO GW 4064 results in increased expression of CDC7 mRNA CTD PMID:31437187 NCBI chr14:3,826,658...3,846,891
Ensembl chr14:3,826,659...3,846,891
JBrowse link
G Cdh17 cadherin 17 decreases expression ISO GW 4064 results in decreased expression of CDH17 mRNA CTD PMID:26655953 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdhr2 cadherin-related family member 2 increases expression ISO GW 4064 results in increased expression of CDHR2 mRNA CTD PMID:26655953 NCBI chr17:10,415,044...10,450,589
Ensembl chr17:10,415,123...10,439,691
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO GW 4064 results in increased expression of CDK1 mRNA CTD PMID:31437187 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression ISO GW 4064 results in increased expression of CDK2 mRNA CTD PMID:31437187 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to CDK5RAP2 gene] CTD PMID:20091679 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO GW 4064 results in decreased expression of CDKN1A mRNA; GW 4064 results in decreased expression of CDKN1A protein CTD PMID:28496032 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases expression ISO GW 4064 results in decreased expression of CDKN2B mRNA CTD PMID:31437187 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO GW 4064 results in increased expression of CDKN2C mRNA CTD PMID:31437187 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to CEBPB gene] CTD PMID:20091679 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cers2 ceramide synthase 2 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA] CTD PMID:28223344 NCBI chr 2:196,487,656...196,495,930
Ensembl chr 2:196,487,656...196,496,986
JBrowse link
G Cers4 ceramide synthase 4 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA] CTD PMID:28223344 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729
JBrowse link
G Ces2c carboxylesterase 2C increases expression ISO GW 4064 results in increased expression of CES2C mRNA CTD PMID:26655953 NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO GW 4064 results in increased expression of CHEK1 mRNA CTD PMID:31437187 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO GW 4064 results in increased expression of CHEK2 mRNA CTD PMID:31437187 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression ISO GW 4064 results in decreased expression of CHRNA7 mRNA CTD PMID:26655953 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chst13 carbohydrate sulfotransferase 13 increases expression ISO GW 4064 results in increased expression of CHST13 mRNA CTD PMID:26655953 NCBI chr 4:122,223,846...122,244,848
Ensembl chr 4:122,224,535...122,237,754
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to CKS2 gene] CTD PMID:20091679 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldn11 claudin 11 decreases expression ISO GW 4064 results in decreased expression of CLDN11 mRNA CTD PMID:26655953 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clec7a C-type lectin domain containing 7A increases expression ISO GW 4064 results in increased expression of CLEC7A mRNA CTD PMID:26655953 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Clstn2 calsyntenin 2 decreases expression ISO GW 4064 results in decreased expression of CLSTN2 mRNA CTD PMID:26655953 NCBI chr 8:105,322,577...106,036,821
Ensembl chr 8:105,323,837...105,462,168
JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene increases expression ISO GW 4064 results in increased expression of CMAH mRNA CTD PMID:26655953 NCBI chr17:42,567,472...42,640,221
Ensembl chr17:42,583,945...42,640,221
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO GW 4064 results in decreased expression of CMPK2 mRNA CTD PMID:26655953 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cndp1 carnosine dipeptidase 1 increases expression ISO GW 4064 results in increased expression of CNDP1 mRNA CTD PMID:26655953 NCBI chr18:81,466,717...81,512,841
Ensembl chr18:81,466,716...81,499,051
JBrowse link
G Cnnm1 cyclin and CBS domain divalent metal cation transport mediator 1 increases expression ISO GW 4064 results in increased expression of CNNM1 mRNA CTD PMID:26655953 NCBI chr 1:263,184,361...263,243,912
Ensembl chr 1:263,186,235...263,242,468
JBrowse link
G Cnnm3 cyclin and CBS domain divalent metal cation transport mediator 3 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to CNNM3 gene] CTD PMID:20091679 NCBI chr 9:43,093,120...43,108,486
Ensembl chr 9:43,093,138...43,108,486
JBrowse link
G Cntfr ciliary neurotrophic factor receptor increases expression ISO GW 4064 results in increased expression of CNTFR mRNA CTD PMID:26655953 NCBI chr 5:58,041,114...58,078,687
Ensembl chr 5:58,041,146...58,078,545
JBrowse link
G Col16a1 collagen type XVI alpha 1 chain increases expression ISO GW 4064 results in increased expression of COL16A1 mRNA CTD PMID:26655953 NCBI chr 5:148,257,030...148,311,645
Ensembl chr 5:148,257,642...148,311,645
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP GW 4064 results in decreased expression of COL1A1 mRNA CTD PMID:15980055 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of COX10 mRNA CTD PMID:30611723 NCBI chr10:50,439,778...50,563,920
Ensembl chr10:50,439,782...50,574,539
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT1A mRNA CTD PMID:30611723 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA CTD PMID:30611723 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 increases expression ISO GW 4064 results in increased expression of CRABP1 mRNA CTD PMID:26655953 NCBI chr 8:59,344,097...59,352,135
Ensembl chr 8:59,344,083...59,352,132
JBrowse link
G Crct1 cysteine-rich C-terminal 1 decreases expression ISO GW 4064 results in decreased expression of CRCT1 mRNA CTD PMID:26655953 Ensembl chr 2:193,330,397...193,330,699 JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression ISO GW 4064 results in decreased expression of CRISPLD2 mRNA CTD PMID:26655953 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Crygs crystallin, gamma S increases expression ISO GW 4064 results in increased expression of CRYGS mRNA CTD PMID:26655953 NCBI chr11:81,796,891...81,802,172
Ensembl chr11:81,796,891...81,802,172
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO GW 4064 results in increased expression of CSF1 mRNA CTD PMID:31437187 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO GW 4064 results in increased expression of CSF1R mRNA CTD PMID:26655953 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO GW 4064 results in increased expression of CSF2 mRNA CTD PMID:26655953 PMID:31437187 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cubn cubilin increases expression ISO GW 4064 results in increased expression of CUBN mRNA CTD PMID:26655953 NCBI chr17:80,584,921...80,807,181
Ensembl chr17:80,584,878...80,807,243
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO GW 4064 results in increased expression of CYP24A1 mRNA CTD PMID:26655953 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO GW 4064 results in increased expression of CYP27A1 mRNA CTD PMID:27609522 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA
GW 4064 results in decreased expression of CYP2B6 mRNA
CTD PMID:30611723 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA
GW 4064 results in decreased expression of CYP2E1 mRNA
CTD PMID:30611723 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression
ISO
EXP
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA; [GW 4064 results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA; FGFR4 protein affects the reaction [[GW 4064 results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA]
GW 4064 results in decreased expression of CYP7A1 mRNA
CTD PMID:14623915 PMID:15644430 PMID:22467244 PMID:22540009 PMID:27609522 PMID:31437187 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression EXP GW 4064 results in decreased expression of CYP8B1 mRNA CTD PMID:14623915 PMID:15644430 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 decreases expression ISO GW 4064 results in decreased expression of CYSLTR1 mRNA CTD PMID:26655953 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO GW 4064 results in increased expression of DBF4 mRNA CTD PMID:31437187 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA] CTD PMID:28223344 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx43 DEAD-box helicase 43 decreases expression ISO GW 4064 results in decreased expression of DDX43 mRNA CTD PMID:26655953 NCBI chr 8:85,749,499...85,779,068
Ensembl chr 8:85,750,082...85,777,510
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA CTD PMID:30611723 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA] CTD PMID:28223344 NCBI chr 6:132,591,968...132,608,600
Ensembl chr 6:132,591,969...132,608,600
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of DGAT1 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT1 mRNA
CTD PMID:30611723 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of DGAT2 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT2 mRNA
CTD PMID:30611723 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase subunit increases expression
multiple interactions
ISO GW 4064 results in increased expression of DHDDS mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DHDDS mRNA
CTD PMID:30611723 NCBI chr 5:152,200,681...152,227,669
Ensembl chr 5:152,199,584...152,227,677
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO GW 4064 results in decreased expression of DIO1 mRNA CTD PMID:26655953 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dlgap3 DLG associated protein 3 increases expression ISO GW 4064 results in increased expression of DLGAP3 mRNA CTD PMID:26655953 NCBI chr 5:145,234,757...145,304,536
Ensembl chr 5:145,257,714...145,304,536
JBrowse link
G Dmc1 DNA meiotic recombinase 1 increases expression ISO GW 4064 results in increased expression of DMC1 mRNA CTD PMID:26655953 NCBI chr 7:120,796,217...120,840,524
Ensembl chr 7:120,796,217...120,839,577
JBrowse link
G Dnaaf6 dynein axonemal assembly factor 6 increases expression ISO GW 4064 results in increased expression of DNAAF6B mRNA CTD PMID:26655953 NCBI chr  X:111,389,557...111,439,399
Ensembl chr  X:111,396,995...111,439,376
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 increases expression ISO GW 4064 results in increased expression of DNAH1 mRNA CTD PMID:26655953 NCBI chr16:7,345,131...7,407,009
Ensembl chr16:7,345,978...7,408,265
JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO GW 4064 results in increased expression of DNASE1 mRNA CTD PMID:26655953 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 increases expression ISO GW 4064 results in increased expression of DNPH1 mRNA CTD PMID:26655953 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Dock2 dedicator of cytokinesis 2 decreases expression ISO GW 4064 results in decreased expression of DOCK2 mRNA CTD PMID:26655953 NCBI chr10:19,181,512...19,603,171 JBrowse link
G Dusp26 dual specificity phosphatase 26 increases expression ISO GW 4064 results in increased expression of DUSP26 mRNA CTD PMID:26655953 NCBI chr16:64,798,782...64,806,459
Ensembl chr16:64,798,778...64,806,050
JBrowse link
G Ech1 enoyl-CoA hydratase 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ECH1 mRNA CTD PMID:30611723 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ECHS1 mRNA CTD PMID:30611723 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Edn1 endothelin 1 decreases expression EXP GW 4064 results in decreased expression of EDN1 mRNA CTD PMID:16357303 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Efcab10 EF-hand calcium binding domain 10 increases expression ISO GW 4064 results in increased expression of EFCAB10 mRNA CTD PMID:26655953 NCBI chr 6:52,702,304...52,709,223
Ensembl chr 6:52,702,544...52,709,223
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 decreases expression ISO GW 4064 results in decreased expression of EGLN3 mRNA CTD PMID:26655953 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of EHHADH mRNA CTD PMID:30611723 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Elf5 E74 like ETS transcription factor 5 decreases expression ISO GW 4064 results in decreased expression of ELF5 mRNA CTD PMID:26655953 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to ELL2 gene] CTD PMID:20091679 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO GW 4064 results in increased expression of ELOVL1 mRNA CTD PMID:30611723 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL5 mRNA CTD PMID:30611723 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL6 mRNA CTD PMID:30611723 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Emid1 EMI domain containing 1 increases expression ISO GW 4064 results in increased expression of EMID1 mRNA CTD PMID:26655953 NCBI chr14:85,357,221...85,400,396
Ensembl chr14:85,357,222...85,398,532
JBrowse link
G Eno1 enolase 1 decreases expression ISO GW 4064 results in decreased expression of ENO1 protein CTD PMID:23178280 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO GW 4064 results in decreased expression of ENPP2 mRNA CTD PMID:26655953 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 increases expression ISO GW 4064 results in increased expression of ENPP6 mRNA CTD PMID:26655953 NCBI chr16:48,315,500...48,437,258
Ensembl chr16:48,315,914...48,437,242
JBrowse link
G Epgn epithelial mitogen decreases expression ISO GW 4064 results in decreased expression of EPGN mRNA CTD PMID:26655953 NCBI chr14:18,627,103...18,635,135
Ensembl chr14:18,626,644...18,634,309
JBrowse link
G Epha7 Eph receptor A7 increases expression ISO GW 4064 results in increased expression of EPHA7 mRNA CTD PMID:26655953 NCBI chr 5:43,602,744...43,761,198
Ensembl chr 5:43,603,043...43,757,549
JBrowse link
G Eps8l3 EPS8 like 3 increases expression ISO GW 4064 results in increased expression of EPS8L3 mRNA CTD PMID:26655953 NCBI chr 2:210,668,249...210,681,930
Ensembl chr 2:210,668,403...210,681,796
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO GW 4064 results in decreased expression of ERBB4 mRNA CTD PMID:26655953 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope increases expression ISO GW 4064 results in increased expression of SYNA mRNA CTD PMID:26655953 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182
JBrowse link
G Esam endothelial cell adhesion molecule increases expression ISO GW 4064 results in increased expression of ESAM mRNA CTD PMID:26655953 NCBI chr 8:39,997,875...40,008,802
Ensembl chr 8:39,997,875...40,008,809
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase increases expression ISO GW 4064 results in increased expression of ESPL1 mRNA CTD PMID:31437187 NCBI chr 7:143,896,890...143,923,868
Ensembl chr 7:143,897,014...143,923,868
JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase increases expression ISO GW 4064 results in increased expression of ETNPPL mRNA CTD PMID:26655953 NCBI chr 2:235,738,377...235,760,351
Ensembl chr 2:235,738,416...235,760,352
JBrowse link
G Fa2h fatty acid 2-hydroxylase decreases expression ISO GW 4064 results in decreased expression of FA2H mRNA CTD PMID:26655953 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of FABP1 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of FABP1 mRNA
CTD PMID:30611723 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp6 fatty acid binding protein 6 multiple interactions
increases expression
ISO NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of FABP6 mRNA] CTD PMID:22918042 PMID:26655953 NCBI chr10:29,191,621...29,196,593
Ensembl chr10:29,191,623...29,196,563
JBrowse link
G Fam163a family with sequence similarity 163, member A decreases expression ISO GW 4064 results in decreased expression of FAM163A mRNA CTD PMID:26655953 NCBI chr13:73,741,674...73,820,114
Ensembl chr13:73,741,679...73,819,896
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 decreases expression ISO GW 4064 results in decreased expression of FAM171A2 mRNA CTD PMID:26655953 NCBI chr10:90,383,111...90,393,476
Ensembl chr10:90,383,813...90,393,317
JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP GW 4064 results in decreased expression of FAS mRNA CTD PMID:14623915 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of FASN mRNA CTD PMID:30611723 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression ISO GW 4064 results in increased expression of FBP2 mRNA CTD PMID:26655953 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fbxo40 F-box protein 40 increases expression ISO GW 4064 results in increased expression of FBXO40 mRNA CTD PMID:26655953 NCBI chr11:66,713,913...66,731,195
Ensembl chr11:66,713,888...66,731,198
JBrowse link
G Fcna ficolin A multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to FCNA gene] CTD PMID:20091679 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of FDFT1 mRNA CTD PMID:30611723 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fga fibrinogen alpha chain multiple interactions
increases expression
ISO GW 4064 promotes the reaction [NR1H4 protein binds to FGA gene]
GW 4064 results in increased expression of FGA mRNA
CTD PMID:20091679 PMID:26655953 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgf19 fibroblast growth factor 19 increases expression
multiple interactions
ISO GW 4064 results in increased expression of FGF15 mRNA; GW 4064 results in increased expression of FGF15 protein; GW 4064 results in increased expression of FGF19 mRNA; GW 4064 results in increased expression of FGF19 protein
[[GW 4064 results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA; [GW 4064 results in increased activity of NR1H4 protein] which binds to FGF19 promoter
[GW 4064 co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA; epiallopregnanolone sulfate inhibits the reaction [GW 4064 results in increased expression of FGF19 mRNA]; epiallopregnanolone sulfate inhibits the reaction [GW 4064 results in increased expression of FGF19 protein]; FGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]; FGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG8 mRNA]; FGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of SCARB1 mRNA]; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA]; GW 4064 promotes the reaction [NR1H4 protein binds to FGF15 gene]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of FGF15 mRNA]
CTD PMID:16269825 PMID:20091679 PMID:22561792 PMID:22918042 PMID:22961653 PMID:27609522 PMID:28223344 PMID:30996006 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO GW 4064 results in increased expression of FGF21 mRNA CTD PMID:26655953 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 multiple interactions ISO FGFR4 protein affects the reaction [[GW 4064 results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA] CTD PMID:22467244 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G Flacc1 flagellum associated containing coiled-coil domains 1 increases expression ISO GW 4064 results in increased expression of FLACC1 mRNA CTD PMID:26655953 NCBI chr 9:65,665,663...65,693,822
Ensembl chr 9:65,665,664...65,693,822
JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTA mRNA CTD PMID:30611723 NCBI chr16:70,834,957...70,854,724
Ensembl chr16:70,834,957...70,854,724
JBrowse link
G Fntb farnesyltransferase, CAAX box, beta multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTB mRNA CTD PMID:30611723 NCBI chr 6:99,883,959...99,966,988
Ensembl chr 6:99,883,959...99,966,988
JBrowse link
G Frzb frizzled-related protein decreases expression ISO GW 4064 results in decreased expression of FRZB mRNA CTD PMID:26655953 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions
decreases expression
ISO bisphenol A inhibits the reaction [GW 4064 results in decreased expression of FSHR mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of FSHR mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of FSHR mRNA] CTD PMID:30245210 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fst follistatin decreases expression ISO GW 4064 results in decreased expression of FST mRNA CTD PMID:26655953 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression
increases expression
ISO GW 4064 results in decreased expression of G6PC mRNA
GW 4064 results in increased expression of G6PC mRNA
CTD PMID:23371517 PMID:26655953 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO GW 4064 results in increased expression of GAS7 mRNA CTD PMID:26655953 NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
JBrowse link
G Gatd1 glutamine amidotransferase like class 1 domain containing 1 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to GATD1 gene] CTD PMID:20091679 NCBI chr 1:214,389,006...214,394,451
Ensembl chr 1:214,389,255...214,394,411
JBrowse link
G Gatm glycine amidinotransferase increases expression ISO GW 4064 results in increased expression of GATM mRNA CTD PMID:26655953 NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator increases expression ISO GW 4064 results in increased expression of GCHFR mRNA CTD PMID:26655953 NCBI chr 3:110,975,923...110,979,957
Ensembl chr 3:110,975,923...110,979,957
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO GW 4064 results in increased expression of GCLM mRNA CTD PMID:26655953 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions
decreases expression
ISO bisphenol A inhibits the reaction [GW 4064 results in decreased expression of GFRA1 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of GFRA1 mRNA] CTD PMID:30245210 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Ggps1 geranylgeranyl diphosphate synthase 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of GGPS1 mRNA CTD PMID:30611723 NCBI chr17:53,956,185...53,971,039
Ensembl chr17:53,956,203...53,971,443
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO GW 4064 results in increased expression of GGT1 mRNA CTD PMID:26655953 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gimap1 GTPase, IMAP family member 1 increases expression ISO GW 4064 results in increased expression of GIMAP1 mRNA CTD PMID:26655953 NCBI chr 4:78,365,276...78,375,450
Ensembl chr 4:78,371,121...78,375,223
JBrowse link
G Gimap8 GTPase, IMAP family member 8 increases expression ISO GW 4064 results in increased expression of GIMAP8 mRNA CTD PMID:26655953 NCBI chr 4:78,283,356...78,294,838
Ensembl chr 4:78,283,026...78,294,845
JBrowse link
G Gldc glycine decarboxylase increases expression ISO GW 4064 results in increased expression of GLDC mRNA CTD PMID:26655953 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
G Glipr2 GLI pathogenesis-related 2 increases expression ISO GW 4064 results in increased expression of GLIPR2 mRNA CTD PMID:26655953 NCBI chr 5:59,415,415...59,446,732
Ensembl chr 5:59,416,076...59,446,647
JBrowse link
G Glyctk glycerate kinase increases expression ISO GW 4064 results in increased expression of GLYCTK mRNA CTD PMID:26655953 NCBI chr 8:114,846,210...114,853,374
Ensembl chr 8:114,848,084...114,853,103
JBrowse link
G Gna14 G protein subunit alpha 14 increases expression ISO GW 4064 results in increased expression of GNA14 mRNA CTD PMID:26655953 NCBI chr 1:235,165,775...235,347,986
Ensembl chr 1:235,166,718...235,347,937
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of GNMT mRNA
NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of GNMT mRNA]
CTD PMID:29416063 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 multiple interactions
increases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT3 mRNA
GW 4064 results in increased expression of GPAT3 mRNA
CTD PMID:30611723 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA CTD PMID:30611723 NCBI chr16:73,615,949...73,649,769
Ensembl chr16:73,615,949...73,649,767
JBrowse link
G Gpbp1 GC-rich promoter binding protein 1 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to GPBP1 gene] CTD PMID:20091679 NCBI chr 2:43,002,041...43,070,236
Ensembl chr 2:43,002,044...43,068,677
JBrowse link
G Gpr50 G protein-coupled receptor 50 increases expression ISO GW 4064 results in increased expression of GPR50 mRNA CTD PMID:26655953 NCBI chr17:36,771,578...36,776,225
Ensembl chr17:36,771,639...36,776,225
JBrowse link
G Gpt glutamic--pyruvic transaminase decreases activity EXP GW 4064 results in decreased activity of GPT protein CTD PMID:14623915 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO GW 4064 results in increased expression of GPX1 mRNA CTD PMID:26655953 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsn gelsolin increases expression ISO GW 4064 results in increased expression of GSN mRNA CTD PMID:26655953 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO GW 4064 results in increased expression of GSR mRNA CTD PMID:26655953 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO GW 4064 results in increased expression of GSTA1 mRNA CTD PMID:26655953 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO GW 4064 results in increased expression of GSTA2 mRNA CTD PMID:26655953 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO GW 4064 results in increased expression of GSTA1 mRNA CTD PMID:26655953 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO GW 4064 results in increased expression of GSTM1 mRNA CTD PMID:26655953 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO GW 4064 results in increased expression of GSTM3 mRNA CTD PMID:26655953 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gtf2a2 general transcription factor 2A subunit 2 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to GTF2A2 gene] CTD PMID:20091679 NCBI chr 8:76,422,341...76,435,587
Ensembl chr 8:76,422,359...76,435,473
JBrowse link
G Gtsf1 gametocyte specific factor 1 decreases expression ISO GW 4064 results in decreased expression of GTSF1 mRNA CTD PMID:26655953 NCBI chr 7:145,030,139...145,049,183
Ensembl chr 7:145,029,699...145,048,283
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression
increases expression
ISO GW 4064 results in decreased expression of HAAO protein
GW 4064 results in increased expression of HAAO mRNA
CTD PMID:23178280 PMID:26655953 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADH mRNA CTD PMID:30611723 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADHA mRNA CTD PMID:30611723 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hes2 hes family bHLH transcription factor 2 decreases expression ISO GW 4064 results in decreased expression of HES2 mRNA CTD PMID:26655953 NCBI chr 5:169,338,097...169,339,142
Ensembl chr 5:169,338,097...169,339,142
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like increases expression ISO GW 4064 results in increased expression of HEYL mRNA CTD PMID:26655953 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase increases expression ISO GW 4064 results in increased expression of HGD mRNA CTD PMID:26655953 NCBI chr11:65,983,221...66,034,555
Ensembl chr11:65,983,221...66,034,573
JBrowse link
G Hhex hematopoietically expressed homeobox multiple interactions
increases expression
ISO NR1H4 mutant form inhibits the reaction [GW 4064 results in increased expression of HHEX mRNA] CTD PMID:19072826 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO GW 4064 results in decreased expression of HIF1A mRNA CTD PMID:26655953 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha decreases expression ISO GW 4064 results in decreased expression of HIF3A mRNA CTD PMID:26655953 NCBI chr 1:78,976,318...78,997,869
Ensembl chr 1:78,976,318...78,997,869
JBrowse link
G Hivep3 HIVEP zinc finger 3 increases expression ISO GW 4064 results in increased expression of HIVEP3 mRNA CTD PMID:26655953 NCBI chr 5:138,774,501...139,077,403
Ensembl chr 5:139,007,642...139,077,377
JBrowse link
G Hkdc1 hexokinase domain containing 1 decreases expression ISO GW 4064 results in decreased expression of HKDC1 mRNA CTD PMID:26655953 NCBI chr20:32,018,027...32,054,494 JBrowse link
G Hmga1 high mobility group AT-hook 1 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to HMGA1 gene] CTD PMID:20091679 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO GW 4064 results in increased expression of HMGCR mRNA CTD PMID:30611723 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO GW 4064 results in decreased expression of HMGCS2 mRNA CTD PMID:31437187 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
decreases expression
affects expression
ISO GW 4064 results in increased expression of HNF4A mRNA
GW 4064 results in decreased expression of HNF4A mRNA
GW 4064 affects the expression of HNF4A mRNA
CTD PMID:26655953 PMID:31437187 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO GW 4064 results in decreased expression of HNMT mRNA CTD PMID:26655953 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Homer2 homer scaffold protein 2 increases expression ISO GW 4064 results in increased expression of HOMER2 mRNA CTD PMID:26655953 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Hrg histidine-rich glycoprotein decreases expression ISO GW 4064 results in decreased expression of HRG mRNA CTD PMID:26655953 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 increases expression ISO GW 4064 results in increased expression of HSD3B3 mRNA CTD PMID:26655953 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA] CTD PMID:28223344 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO GW 4064 results in increased expression of HYOU1 protein CTD PMID:23178280 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO GW 4064 results in increased expression of ICAM1 mRNA CTD PMID:16582018 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Icam5 intercellular adhesion molecule 5 increases expression ISO GW 4064 results in increased expression of ICAM5 mRNA CTD PMID:26655953 NCBI chr 8:22,050,222...22,057,209
Ensembl chr 8:22,050,222...22,057,209
JBrowse link
G Icos inducible T-cell co-stimulator decreases expression ISO GW 4064 results in decreased expression of ICOS mRNA CTD PMID:26655953 NCBI chr 9:67,748,157...67,786,808
Ensembl chr 9:67,763,897...67,785,580
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein decreases expression ISO GW 4064 results in decreased expression of ID4 mRNA CTD PMID:26655953 NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 increases expression ISO GW 4064 results in increased expression of IGF2BP3 mRNA CTD PMID:26655953 NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to IGFALS gene] CTD PMID:20091679 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO GW 4064 results in increased expression of IGFBP1 mRNA CTD PMID:26655953 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Il11 interleukin 11 increases expression ISO GW 4064 results in increased expression of IL11 mRNA CTD PMID:26655953 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il17b interleukin 17B multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to IL17B gene] CTD PMID:20091679 NCBI chr18:57,011,575...57,016,009
Ensembl chr18:57,011,575...57,016,009
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO GW 4064 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]
GW 4064 results in increased expression of IL1B mRNA
GW 4064 results in decreased expression of IL1B mRNA
CTD PMID:21242261 PMID:23371517 PMID:31437187 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO GW 4064 results in increased expression of IL4R mRNA CTD PMID:31437187 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA
GW 4064 results in increased expression of IL6 mRNA
CTD PMID:30611723 PMID:31437187 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression ISO GW 4064 results in increased expression of INMT mRNA CTD PMID:26655953 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 decreases expression ISO GW 4064 results in decreased expression of IP6K3 mRNA CTD PMID:26655953 NCBI chr20:5,733,485...5,754,859
Ensembl chr20:5,733,482...5,754,773
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO GW 4064 results in decreased expression of ISG15 mRNA CTD PMID:26655953 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO GW 4064 results in decreased expression of ITGAM mRNA CTD PMID:23371517 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgax integrin subunit alpha X decreases expression
increases expression
ISO GW 4064 results in decreased expression of ITGAX mRNA
GW 4064 results in increased expression of ITGAX mRNA
CTD PMID:23371517 PMID:26655953 NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression ISO GW 4064 results in increased expression of ITIH3 mRNA CTD PMID:26655953 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA] CTD PMID:28223344 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jakmip1 janus kinase and microtubule interacting protein 1 decreases expression ISO GW 4064 results in decreased expression of JAKMIP1 mRNA CTD PMID:26655953 NCBI chr14:78,403,448...78,523,108
Ensembl chr14:78,424,960...78,469,480
JBrowse link
G Jph2 junctophilin 2 increases expression ISO GW 4064 results in increased expression of JPH2 mRNA CTD PMID:26655953 NCBI chr 3:159,709,998...159,776,536
Ensembl chr 3:159,712,325...159,775,643
JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 decreases expression ISO GW 4064 results in decreased expression of KBTBD11 mRNA CTD PMID:26655953 NCBI chr16:79,696,395...79,716,129
Ensembl chr16:79,696,891...79,700,992
JBrowse link
G Kbtbd13 kelch repeat and BTB domain containing 13 increases expression ISO GW 4064 results in increased expression of KBTBD13 mRNA CTD PMID:26655953 NCBI chr 8:70,907,934...70,909,671 JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 increases expression ISO GW 4064 results in increased expression of KCNE4 mRNA CTD PMID:26655953 NCBI chr 9:84,688,873...84,693,066
Ensembl chr 9:84,689,150...84,690,338
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 decreases expression ISO GW 4064 results in decreased expression of KCNE1L mRNA CTD PMID:26655953 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcnh8 potassium voltage-gated channel subfamily H member 8 decreases expression ISO GW 4064 results in decreased expression of KCNH8 mRNA CTD PMID:26655953 NCBI chr 9:3,127,618...3,697,736
Ensembl chr 9:3,127,618...3,697,736
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression ISO GW 4064 results in decreased expression of KCNIP3 mRNA CTD PMID:26655953 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136
JBrowse link
G Kcnip4 potassium voltage-gated channel interacting protein 4 increases expression ISO GW 4064 results in increased expression of KCNIP4 mRNA CTD PMID:26655953 NCBI chr14:65,549,362...66,749,181
Ensembl chr14:66,598,259...66,749,178
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases expression ISO GW 4064 results in decreased expression of KCNJ4 mRNA CTD PMID:26655953 NCBI chr 7:120,717,378...120,744,602
Ensembl chr 7:120,717,375...120,744,602
JBrowse link
G Kif5a kinesin family member 5A increases expression ISO GW 4064 results in increased expression of KIF5A mRNA CTD PMID:26655953 NCBI chr 7:70,515,832...70,552,897
Ensembl chr 7:70,513,343...70,556,827
JBrowse link
G Klhl14 kelch-like family member 14 decreases expression ISO GW 4064 results in decreased expression of KLHL14 mRNA CTD PMID:26655953 NCBI chr18:12,526,627...12,640,381
Ensembl chr18:12,528,111...12,640,716
JBrowse link
G Kmo kynurenine 3-monooxygenase increases expression ISO GW 4064 results in increased expression of KMO mRNA CTD PMID:26655953 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kng2 kininogen 2 multiple interactions
increases expression
ISO alpha-Linolenic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA]; Arachidonic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA]; Docosahexaenoic Acids inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA] CTD PMID:15307955 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt17 keratin 17 increases expression ISO GW 4064 results in increased expression of KRT17 mRNA CTD PMID:26655953 NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
JBrowse link
G Kynu kynureninase increases expression ISO GW 4064 results in increased expression of KYNU mRNA CTD PMID:26655953 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lama4 laminin subunit alpha 4 decreases expression ISO GW 4064 results in decreased expression of LAMA4 mRNA CTD PMID:26655953 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lce1f late cornified envelope 1F increases expression ISO GW 4064 results in increased expression of LCE1F mRNA CTD PMID:26655953 NCBI chr 2:192,990,607...192,992,193
Ensembl chr 2:192,990,831...192,991,199
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to LDHA gene] CTD PMID:20091679 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lgi2 leucine-rich repeat LGI family, member 2 decreases expression ISO GW 4064 results in decreased expression of LGI2 mRNA CTD PMID:26655953 NCBI chr14:60,764,325...60,791,809
Ensembl chr14:60,764,409...60,796,116
JBrowse link
G Lgi3 leucine-rich repeat LGI family, member 3 decreases expression ISO GW 4064 results in decreased expression of LGI3 mRNA CTD PMID:26655953 NCBI chr15:52,220,578...52,227,706
Ensembl chr15:52,220,578...52,227,706
JBrowse link
G Lhx9 LIM homeobox 9 decreases expression ISO GW 4064 results in decreased expression of LHX9 mRNA CTD PMID:26655953 NCBI chr13:55,854,543...55,879,305
Ensembl chr13:55,861,015...55,878,094
JBrowse link
G Lipc lipase C, hepatic type decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of LIPC mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of LIPC mRNA
CTD PMID:30611723 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G LOC102550598 small proline-rich protein 2I-like decreases expression ISO GW 4064 results in decreased expression of SPRR2G mRNA CTD PMID:26655953 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G LOC103690086 uncharacterized LOC103690086 decreases expression ISO GW 4064 results in decreased expression of GBP6 mRNA CTD PMID:26655953 NCBI chr14:5,642,357...5,646,406 JBrowse link
G LOC684709 similar to putative membrane protein Re9 increases expression ISO GW 4064 results in increased expression of TEDDM1 mRNA CTD PMID:26655953 NCBI chr13:71,304,452...71,308,203
Ensembl chr13:71,305,548...71,306,456
JBrowse link
G LOC687097 similar to Olfactory receptor 5B2 (OST073) (Olfactory receptor OR11-240) decreases expression ISO GW 4064 results in decreased expression of OLFR1442 mRNA CTD PMID:26655953 NCBI chr 1:230,297,234...230,298,178
Ensembl chr 1:230,297,117...230,298,184
JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 increases expression ISO GW 4064 results in increased expression of LPAR3 mRNA CTD PMID:26655953 NCBI chr 2:252,090,634...252,159,221
Ensembl chr 2:252,090,669...252,159,903
JBrowse link
G Lpin1 lipin 1 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN1 mRNA
GW 4064 results in decreased expression of LPIN1 mRNA
CTD PMID:30611723 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lpin2 lipin 2 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of LPIN2 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA
CTD PMID:30611723 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G Lpin3 lipin 3 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of LPIN3 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA
CTD PMID:30611723 NCBI chr 3:156,874,805...156,899,601
Ensembl chr 3:156,886,454...156,899,436
JBrowse link
G Lrrc25 leucine rich repeat containing 25 increases expression ISO GW 4064 results in increased expression of LRRC25 mRNA CTD PMID:26655953 NCBI chr16:20,556,973...20,563,773
Ensembl chr16:20,558,222...20,562,399
JBrowse link
G Lrrc43 leucine rich repeat containing 43 increases expression ISO GW 4064 results in increased expression of LRRC43 mRNA CTD PMID:26655953 NCBI chr12:38,507,102...38,524,715
Ensembl chr12:38,507,044...38,525,432
JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 decreases expression ISO GW 4064 results in decreased expression of LRRN3 mRNA CTD PMID:26655953 NCBI chr 6:61,374,328...61,405,195
Ensembl chr 6:61,374,328...61,405,195
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 increases expression ISO GW 4064 results in increased expression of LTBP1 mRNA CTD PMID:26655953 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression ISO GW 4064 results in increased expression of MAD2L1 mRNA CTD PMID:31437187 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases expression
ISO GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; NR1H4 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]; SOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]
GW 4064 results in increased expression of MAPK8 mRNA
GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]
CTD PMID:25496033 PMID:26655953 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; NR1H4 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]]; SOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]]
GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]
CTD PMID:25496033 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mcat malonyl-CoA-acyl carrier protein transacylase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of MCAT mRNA CTD PMID:30611723 NCBI chr 7:124,412,762...124,424,966
Ensembl chr 7:124,412,762...124,423,832
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO GW 4064 results in increased expression of MCM2 mRNA CTD PMID:31437187 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO GW 4064 results in increased expression of MCM4 mRNA CTD PMID:31437187 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression ISO GW 4064 results in increased expression of MCM5 mRNA CTD PMID:31437187 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO GW 4064 results in increased expression of MCM6 mRNA CTD PMID:31437187 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 increases expression ISO GW 4064 results in increased expression of MCM7 mRNA CTD PMID:31437187 NCBI chr12:19,306,615...19,313,877
Ensembl chr12:19,306,607...19,314,016
JBrowse link
G Me3 malic enzyme 3 decreases expression ISO GW 4064 results in decreased expression of ME3 mRNA CTD PMID:26655953 NCBI chr 1:153,861,535...154,058,608
Ensembl chr 1:153,861,569...154,056,654
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of MECR mRNA CTD PMID:30611723 NCBI chr 5:150,001,281...150,027,407
Ensembl chr 5:150,001,281...150,027,049
JBrowse link
G Megf11 multiple EGF-like-domains 11 decreases expression ISO GW 4064 results in decreased expression of MEGF11 mRNA CTD PMID:26655953 NCBI chr 8:69,859,256...70,191,070
Ensembl chr 8:69,971,778...70,184,742
JBrowse link
G Megf6 multiple EGF-like-domains 6 increases expression ISO GW 4064 results in increased expression of MEGF6 mRNA CTD PMID:26655953 NCBI chr 5:171,588,901...171,620,947
Ensembl chr 5:171,472,273...171,620,947
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO GW 4064 results in increased expression of MEOX1 mRNA CTD PMID:26655953 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491
JBrowse link
G Mettl7b methyltransferase like 7B increases expression ISO GW 4064 results in increased expression of METTL7B mRNA CTD PMID:26655953 NCBI chr 7:3,383,876...3,386,522
Ensembl chr 7:3,383,879...3,386,522
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA] CTD PMID:28223344 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression ISO GW 4064 results in decreased expression of MFSD2A mRNA CTD PMID:26655953 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mgarp mitochondria-localized glutamic acid-rich protein decreases expression ISO GW 4064 results in decreased expression of MGARP mRNA CTD PMID:26655953 NCBI chr 2:140,444,963...140,453,719
Ensembl chr 2:140,444,965...140,453,107
JBrowse link
G Mindy4 MINDY lysine 48 deubiquitinase 4 increases expression ISO GW 4064 results in increased expression of MINDY4 mRNA CTD PMID:26655953 NCBI chr 4:85,427,741...85,536,264
Ensembl chr 4:85,427,555...85,532,238
JBrowse link
G Miox myo-inositol oxygenase increases expression ISO GW 4064 results in increased expression of MIOX mRNA CTD PMID:26655953 NCBI chr 7:130,308,707...130,311,205
Ensembl chr 7:130,308,532...130,313,727
JBrowse link
G Mir126a microRNA 126a multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to MIR126 gene] CTD PMID:20091679 NCBI chr 3:4,042,464...4,042,581
Ensembl chr 3:4,042,464...4,042,581
JBrowse link
G Mir499a microRNA 499a multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to MIR499 gene] CTD PMID:20091679 NCBI chr 3:151,138,862...151,138,926
Ensembl chr 3:151,138,862...151,138,926
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of MLXIPL mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA
CTD PMID:30611723 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO GW 4064 results in decreased expression of MMP7 mRNA CTD PMID:26655953 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 increases expression ISO GW 4064 results in increased expression of MOGAT2 mRNA CTD PMID:26655953 NCBI chr 1:164,181,762...164,205,222
Ensembl chr 1:164,181,764...164,205,222
JBrowse link
G Mtfmt mitochondrial methionyl-tRNA formyltransferase multiple interactions
decreases expression
ISO NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of MTFMT mRNA] CTD PMID:29416063 NCBI chr 8:70,952,209...70,986,393
Ensembl chr 8:70,952,203...70,986,408
JBrowse link
G Mthfr methylenetetrahydrofolate reductase decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of MTHFR mRNA
NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of MTHFR mRNA]
CTD PMID:29416063 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA
GW 4064 results in decreased expression of MTTP mRNA
CTD PMID:30611723 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO GW 4064 results in increased expression of MUC13 mRNA CTD PMID:26655953 NCBI chr11:70,185,757...70,223,012
Ensembl chr11:70,185,757...70,211,701
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO GW 4064 results in decreased expression of MX1 mRNA CTD PMID:26655953 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression ISO GW 4064 results in increased expression of MYBL1 mRNA CTD PMID:26655953 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Mybpc2 myosin binding protein C2 decreases expression ISO GW 4064 results in decreased expression of MYBPC2 mRNA CTD PMID:26655953 NCBI chr 1:100,506,704...100,530,201
Ensembl chr 1:100,506,704...100,530,183
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO GW 4064 results in increased expression of MYC mRNA CTD PMID:31437187 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh3 myosin heavy chain 3 decreases expression ISO GW 4064 results in decreased expression of MYH3 mRNA CTD PMID:26655953 NCBI chr10:53,621,375...53,645,194
Ensembl chr10:53,621,375...53,645,194
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO GW 4064 results in decreased expression of MYLIP mRNA CTD PMID:31437187 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Mylpf myosin light chain, phosphorylatable, fast skeletal muscle decreases expression ISO GW 4064 results in decreased expression of MYLPF mRNA CTD PMID:26655953 NCBI chr 1:198,655,835...198,658,590
Ensembl chr 1:198,655,742...198,658,583
JBrowse link
G Myo18b myosin XVIIIb increases expression ISO GW 4064 results in increased expression of MYO18B mRNA CTD PMID:26655953 NCBI chr12:49,761,100...49,979,745
Ensembl chr12:49,761,120...49,979,758
JBrowse link
G Myo1f myosin IF increases expression ISO GW 4064 results in increased expression of MYO1F mRNA CTD PMID:26655953 NCBI chr 7:18,440,742...18,491,448
Ensembl chr 7:18,440,742...18,491,448
JBrowse link
G Myo1h myosin IH decreases expression ISO GW 4064 results in decreased expression of MYO1H mRNA CTD PMID:26655953 NCBI chr12:48,025,946...48,095,967 JBrowse link
G Nanog Nanog homeobox decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of NANOG mRNA
bisphenol A inhibits the reaction [GW 4064 results in decreased expression of NANOG mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of NANOG mRNA]
CTD PMID:30245210 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to NAT2 gene] CTD PMID:20091679 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Nat8b N-acetyltransferase 8B increases expression ISO GW 4064 results in increased expression of NAT8B mRNA CTD PMID:26655953 NCBI chr 4:117,606,022...117,607,366
Ensembl chr 4:117,606,022...117,607,428
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO GW 4064 promotes the reaction [NCOA1 protein binds to NR1H4 protein]; GW 4064 promotes the reaction [NR1H4 protein binds to NCOA1 protein] CTD PMID:14684751 PMID:21256005 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 increases expression ISO GW 4064 results in increased expression of NCOA7 mRNA CTD PMID:26655953 NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
JBrowse link
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 decreases expression ISO GW 4064 results in decreased expression of NDUFA4L2 mRNA CTD PMID:26655953 NCBI chr 7:70,821,904...70,824,085
Ensembl chr 7:70,821,957...70,824,085
JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 increases expression ISO GW 4064 results in increased expression of NECAB2 mRNA CTD PMID:26655953 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629
JBrowse link
G Necab3 N-terminal EF-hand calcium binding protein 3 increases expression ISO GW 4064 results in increased expression of NECAB3 mRNA CTD PMID:26655953 NCBI chr 3:150,047,826...150,062,806
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Nhsl2 NHS-like 2 increases expression ISO GW 4064 results in increased expression of NHSL2 mRNA CTD PMID:26655953 NCBI chr  X:71,895,202...71,980,019 JBrowse link
G Nol3 nucleolar protein 3 decreases expression ISO GW 4064 results in decreased expression of NOL3 mRNA CTD PMID:26655953 NCBI chr19:37,232,567...37,236,668
Ensembl chr19:37,235,001...37,236,649
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO GW 4064 results in increased expression of NOS1 mRNA CTD PMID:26655953 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 increases expression ISO GW 4064 results in increased expression of NPM3 mRNA CTD PMID:26655953 NCBI chr 1:265,504,105...265,506,080
Ensembl chr 1:265,504,575...265,506,046
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO GW 4064 results in increased expression of NQO1 mRNA CTD PMID:26655953 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of NR0B1 mRNA
GW 4064 promotes the reaction [Stigmasterol results in increased expression of NR0B1 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of NR0B1 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of NR0B1 mRNA]
CTD PMID:30245210 NCBI chr  X:54,734,385...54,738,513
Ensembl chr  X:54,734,385...54,738,513
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
ISO
EXP
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of NR0B2 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of NR0B2 mRNA; epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of NR0B2 mRNA]
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of NR0B2 mRNA; ATP7B protein affects the reaction [GW 4064 results in increased expression of NR0B2 mRNA]; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of NR0B2 mRNA]; GW 4064 inhibits the reaction [ATP7B gene mutant form results in decreased expression of NR0B2 mRNA]; GW 4064 promotes the reaction [NR1H4 protein binds to NR0B2 gene]; NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of AHCYL2 mRNA]; NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of GNMT mRNA]; NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of MTFMT mRNA]; NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of MTHFR mRNA]; NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of PEMT mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of NR0B2 mRNA]; NR1H4 mutant form inhibits the reaction [GW 4064 results in increased expression of NR0B2 mRNA]; Stigmasterol promotes the reaction [GW 4064 results in increased expression of NR0B2 mRNA]
CTD PMID:14623915 PMID:15644430 PMID:15980055 PMID:16269825 PMID:19072826 PMID:20091679 PMID:21480330 PMID:22178739 PMID:22414727 PMID:22540009 PMID:22918042 PMID:23178280 PMID:25550158 PMID:26241054 PMID:27609522 PMID:28223344 PMID:29416063 PMID:30245210 PMID:30611723 PMID:31437187 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
increases expression
increases phosphorylation
decreases expression
decreases response to substance
increases activity
affects binding
ISO
EXP
[[GW 4064 binds to and results in increased activity of NR1H4 protein] which binds to ABCB4 promoter] which results in increased expression of ABCB4 mRNA; [[GW 4064 results in increased activity of NR1H4 protein] which binds to FGF19 promoter] which results in increased expression of FGF19 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of NR0B2 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of SCARB1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [GW 4064 results in increased activity of NR1H4 protein] which binds to FGF19 promoter; [GW 4064 results in increased activity of NR1H4 protein] which results in increased expression of UGT1A3 mRNA; epigallocatechin gallate inhibits the reaction [GW 4064 results in increased activity of NR1H4 protein]; epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of NR1H4 mRNA]; GW 4064 binds to and results in increased activity of NR1H4 protein; GW 4064 inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; GW 4064 inhibits the reaction [TNF protein results in increased expression of NR1H4 mRNA]; GW 4064 promotes the reaction [NCOA1 protein binds to NR1H4 protein]; GW 4064 promotes the reaction [NR1H4 protein binds to NCOA1 protein]; GW 4064 promotes the reaction [NR1H4 protein binds to SOD3 promoter]; GW 4064 promotes the reaction [NR1H4 protein results in increased export of Taurocholic Acid]; NR1H4 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]; NR1H4 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]]
GW 4064 inhibits the reaction [17alpha-ethynylestradiol decreases expression of Nr1h4 mRNA in primary hepatocytes]
GW 4064 increases expression of Nr1h4 mRNA in primary hepatocytes
GW4064 increases expression of Nr1H4 mRNA in rat hepatic stellate cells
gw4064 increases expression of nr1h4 mRNA and protein in rat embryonic liver cells
GW 4064 results in increased phosphorylation of NR1H4 protein
GW 4064 results in decreased expression of NR1H4 mRNA
NR1H4 gene mutant form results in decreased susceptibility to GW 4064
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in decreased expression of SLC10A1 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of ABCB11 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of NR0B2 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of SCARB1 mRNA; [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of SLC51B mRNA; [GW 4064 results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA; FGFR4 protein affects the reaction [[GW 4064 results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA]; GW 4064 binds to and results in increased activity of NR1H4 protein; GW 4064 promotes the reaction [NR1H4 protein binds to ACTG1 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to APOE gene]; GW 4064 promotes the reaction [NR1H4 protein binds to BCCIP gene]; GW 4064 promotes the reaction [NR1H4 protein binds to CAPRIN1 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to CDK5RAP2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to CEBPB gene]; GW 4064 promotes the reaction [NR1H4 protein binds to CKS2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to CNNM3 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to ELL2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to FCNA gene]; GW 4064 promotes the reaction [NR1H4 protein binds to FGA gene]; GW 4064 promotes the reaction [NR1H4 protein binds to FGF15 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to GATD1 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to GPBP1 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to GTF2A2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to HMGA1 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to IGFALS gene]; GW 4064 promotes the reaction [NR1H4 protein binds to IL17B gene]; GW 4064 promotes the reaction [NR1H4 protein binds to LDHA gene]; GW 4064 promotes the reaction [NR1H4 protein binds to MIR126 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to MIR499 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to NAT2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to NR0B2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to PCX gene]; GW 4064 promotes the reaction [NR1H4 protein binds to PDGFRB gene]; GW 4064 promotes the reaction [NR1H4 protein binds to PLAT gene]; GW 4064 promotes the reaction [NR1H4 protein binds to RARRES2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SCARB1 intron]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC10A1 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC22A21 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC25A3 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC51A gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC51B gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC9A8 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to STAT2 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to SUMO3 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to TFAP2E gene]; GW 4064 promotes the reaction [NR1H4 protein binds to TLR3 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to TRPM7 gene]; GW 4064 promotes the reaction [NR1H4 protein binds to VKORC1 gene]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of FSHR mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of NR0B1 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of PDK4 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of STRA8 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of ZBTB16 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCB11 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of ABCG5 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of APOA1 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of FABP6 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of FGF15 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of NR0B2 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of SOD3 mRNA]; NR1H4 mutant form inhibits the reaction [GW 4064 results in increased expression of HHEX mRNA]; NR1H4 mutant form inhibits the reaction [GW 4064 results in increased expression of NR0B2 mRNA]; NR1H4 protein promotes the reaction [GW 4064 results in increased expression of ABCB11 protein]
GW 4064 binds to NR1H4 protein
CTD PMID:12519787 PMID:12525500 PMID:14527955 PMID:14623915 PMID:14684751 PMID:15980055 PMID:16582018 PMID:16946559 PMID:17567710 PMID:19072826 PMID:19445040 PMID:20091679 PMID:20189675 PMID:21242261 PMID:21256005 PMID:21291553 PMID:21480330 PMID:22178739 PMID:22414727 PMID:22467244 PMID:22540009 PMID:22561792 PMID:22918042 PMID:22961653 PMID:24812009 PMID:25257666 PMID:25496033 PMID:25689681 PMID:29968724 PMID:30245210 PMID:30611723, PMID:27090119, PMID:27090119, PMID:15980055, PMID:29235094 RGD:15090804, RGD:15090804, RGD:1625201, RGD:15042872 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO GW 4064 results in increased expression of NR1I2 mRNA CTD PMID:26655953 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA
GW 4064 results in decreased expression of NR1I3 mRNA
CTD PMID:30611723 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Ntsr1 neurotensin receptor 1 decreases expression ISO GW 4064 results in decreased expression of NTSR1 mRNA CTD PMID:26655953 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 decreases expression ISO GW 4064 results in decreased expression of NWD2 mRNA CTD PMID:26655953 NCBI chr14:46,136,780...46,153,320
Ensembl chr14:46,136,786...46,153,212
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO GW 4064 results in decreased expression of OAS2 mRNA CTD PMID:26655953 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161
JBrowse link
G Olfml1 olfactomedin-like 1 increases expression ISO GW 4064 results in increased expression of OLFML1 mRNA CTD PMID:26655953 NCBI chr 1:171,793,782...171,818,074
Ensembl chr 1:171,793,782...171,818,068
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression ISO GW 4064 results in increased expression of ORC1 mRNA CTD PMID:31437187 NCBI chr 5:128,186,651...128,212,901
Ensembl chr 5:128,190,708...128,210,445
JBrowse link
G Orc6 origin recognition complex, subunit 6 increases expression ISO GW 4064 results in increased expression of ORC6 mRNA CTD PMID:31437187 NCBI chr19:27,457,541...27,464,804
Ensembl chr19:27,457,474...27,464,805
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression ISO GW 4064 results in increased expression of OSGIN1 mRNA CTD PMID:26655953 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G Pacs2 phosphofurin acidic cluster sorting protein 2 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of PACS2 mRNA] CTD PMID:28223344 NCBI chr 6:137,824,136...137,889,144
Ensembl chr 6:137,824,213...137,887,418
JBrowse link
G Padi2 peptidyl arginine deiminase 2 increases expression ISO GW 4064 results in increased expression of PADI2 mRNA CTD PMID:26655953 NCBI chr 5:159,428,479...159,471,113
Ensembl chr 5:159,428,515...159,471,144
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases phosphorylation ISO GW 4064 results in decreased phosphorylation of PARP1 protein CTD PMID:23178280 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pc pyruvate carboxylase multiple interactions
increases expression
ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased activity of PC protein]; GW 4064 promotes the reaction [NR1H4 protein binds to PCX gene]
GW 4064 results in increased expression of PCX mRNA
CTD PMID:20091679 PMID:26655953 PMID:28223344 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pcdh8 protocadherin 8 increases expression ISO GW 4064 results in increased expression of PCDH8 mRNA CTD PMID:26655953 NCBI chr15:62,196,469...62,201,498
Ensembl chr15:62,197,060...62,200,837
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of PCK1 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PCK1 mRNA
CTD PMID:23371517 PMID:30611723 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pde6h phosphodiesterase 6H increases expression ISO GW 4064 results in increased expression of PDE6H mRNA CTD PMID:26655953 NCBI chr 4:170,947,723...170,963,046
Ensembl chr 4:170,958,196...170,963,046
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to PDGFRB gene] CTD PMID:20091679 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions
decreases expression
ISO NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of PDK4 mRNA] CTD PMID:25689681 PMID:31437187 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 multiple interactions
decreases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of PDSS1 mRNA
GW 4064 results in decreased expression of PDSS1 mRNA
CTD PMID:30611723 NCBI chr17:90,033,432...90,072,506
Ensembl chr17:90,033,539...90,071,408
JBrowse link
G Pdxk pyridoxal kinase increases expression ISO GW 4064 results in increased expression of PDXK mRNA CTD PMID:26655953 NCBI chr20:10,930,651...10,952,194
Ensembl chr20:10,930,518...10,952,391
JBrowse link
G Pdzd2 PDZ domain containing 2 increases expression ISO GW 4064 results in increased expression of PDZD2 mRNA CTD PMID:26655953 NCBI chr 2:62,399,748...62,520,448
Ensembl chr 2:62,399,748...62,634,785
JBrowse link
G Pdzd3 PDZ domain containing 3 increases expression ISO GW 4064 results in increased expression of PDZD3 mRNA CTD PMID:26655953 NCBI chr 8:48,577,905...48,582,353
Ensembl chr 8:48,577,952...48,582,353
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of PECR mRNA CTD PMID:30611723 NCBI chr 9:79,601,937...79,630,547
Ensembl chr 9:79,601,901...79,630,536
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of PEMT mRNA
NR0B2 protein promotes the reaction [GW 4064 results in decreased expression of PEMT mRNA]
CTD PMID:29416063 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Pgpep1l pyroglutamyl-peptidase I-like increases expression ISO GW 4064 results in increased expression of PGPEP1L mRNA CTD PMID:26655953 NCBI chr 1:129,216,221...129,244,664
Ensembl chr 1:129,216,152...129,217,058
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 increases expression ISO GW 4064 results in increased expression of PHLDA2 mRNA CTD PMID:26655953 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534
JBrowse link
G Pianp PILR alpha associated neural protein decreases expression ISO GW 4064 results in decreased expression of PIANP mRNA CTD PMID:26655953 NCBI chr 4:157,508,862...157,517,676
Ensembl chr 4:157,511,642...157,517,669
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 decreases expression ISO GW 4064 results in decreased expression of PID1 mRNA CTD PMID:26655953 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 increases expression ISO GW 4064 results in increased expression of PIK3AP1 mRNA CTD PMID:26655953 NCBI chr 1:260,527,344...260,679,132
Ensembl chr 1:260,527,781...260,638,915
JBrowse link
G Pla1a phospholipase A1 member A increases expression ISO GW 4064 results in increased expression of PLA1A mRNA CTD PMID:26655953 NCBI chr11:64,882,024...64,919,714
Ensembl chr11:64,882,288...64,919,579
JBrowse link
G Pla2g12b phospholipase A2, group XIIB increases expression ISO GW 4064 results in increased expression of PLA2G12B mRNA CTD PMID:26655953 NCBI chr20:28,989,440...29,007,967
Ensembl chr20:28,989,491...29,007,968
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to PLAT gene] CTD PMID:20091679 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plin2 perilipin 2 increases expression ISO GW 4064 results in increased expression of PLIN2 mRNA CTD PMID:30611723 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Pllp plasmolipin decreases expression ISO GW 4064 results in decreased expression of PLLP mRNA CTD PMID:26655953 NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641
JBrowse link
G Plpp6 phospholipid phosphatase 6 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA CTD PMID:30611723 NCBI chr 1:247,084,228...247,087,080
Ensembl chr 1:247,084,228...247,087,077
JBrowse link
G Pls1 plastin 1 increases expression ISO GW 4064 results in increased expression of PLS1 mRNA CTD PMID:26655953 NCBI chr 8:103,557,361...103,659,625
Ensembl chr 8:103,557,364...103,608,913
JBrowse link
G Plxdc1 plexin domain containing 1 decreases expression ISO GW 4064 results in decreased expression of PLXDC1 mRNA CTD PMID:26655953 NCBI chr10:85,871,122...85,938,085
Ensembl chr10:85,871,122...85,938,085
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 increases expression ISO GW 4064 results in increased expression of PNPLA3 mRNA CTD PMID:26655953 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases expression
ISO pyrazolanthrone inhibits the reaction [GW 4064 results in decreased expression of PON1 mRNA] CTD PMID:16269825 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO GW 4064 results in decreased expression of POU5F1 protein CTD PMID:31932555 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pp2d1 protein phosphatase 2C-like domain containing 1 decreases expression ISO GW 4064 results in decreased expression of PP2D1 mRNA CTD PMID:26655953 NCBI chr14:72,948,241...72,970,335
Ensembl chr14:72,948,124...72,970,329
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
affects expression
multiple interactions
ISO
EXP
GW 4064 results in increased expression of PPARA mRNA
GW 4064 affects the expression of PPARA mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARA mRNA
CTD PMID:15980055 PMID:26655953 PMID:30611723 PMID:31437187 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
EXP
ISO
GW 4064 results in increased expression of PPARG mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARG mRNA
CTD PMID:15980055 PMID:30611723 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 decreases expression ISO GW 4064 results in decreased expression of PPP1R10 mRNA CTD PMID:26655953 NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO GW 4064 results in decreased expression of PPP1R3C mRNA CTD PMID:26655953 NCBI chr 1:255,371,830...255,376,833
Ensembl chr 1:255,371,810...255,376,833
JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression ISO GW 4064 results in decreased expression of PPP1R3G mRNA CTD PMID:26655953 NCBI chr17:29,566,032...29,570,294
Ensembl chr17:29,567,404...29,568,447
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO GW 4064 results in decreased expression of PPP2R2B mRNA CTD PMID:26655953 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 decreases expression ISO GW 4064 results in decreased expression of PPP4R4 mRNA CTD PMID:26655953 NCBI chr 6:127,400,585...127,497,280
Ensembl chr 6:127,400,585...127,497,280
JBrowse link
G Prodh2 proline dehydrogenase 2 increases expression ISO GW 4064 results in increased expression of PRODH2 mRNA CTD PMID:26655953 NCBI chr 1:88,955,125...88,968,501
Ensembl chr 1:88,955,135...88,968,501
JBrowse link
G Prom2 prominin 2 decreases expression ISO GW 4064 results in decreased expression of PROM2 mRNA CTD PMID:26655953 NCBI chr 3:120,087,633...120,107,495
Ensembl chr 3:120,092,582...120,106,697
JBrowse link
G Prr15 proline rich 15 decreases expression ISO GW 4064 results in decreased expression of PRR15 mRNA CTD PMID:26655953 NCBI chr 4:84,478,839...84,481,885
Ensembl chr 4:84,478,839...84,481,883
JBrowse link
G Ptger3 prostaglandin E receptor 3 decreases expression ISO GW 4064 results in decreased expression of PTGER3 mRNA CTD PMID:26655953 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgfr prostaglandin F receptor decreases expression ISO GW 4064 results in decreased expression of PTGFR mRNA CTD PMID:26655953 NCBI chr 2:257,005,813...257,039,036
Ensembl chr 2:257,005,829...257,038,105
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R increases expression ISO GW 4064 results in increased expression of PTPRR mRNA CTD PMID:26655953 NCBI chr 7:59,039,717...59,325,925
Ensembl chr 7:59,039,720...59,325,947
JBrowse link
G Rab11fip4 RAB11 family interacting protein 4 increases expression ISO GW 4064 results in increased expression of RAB11FIP4 mRNA CTD PMID:26655953 NCBI chr10:66,942,363...67,051,672
Ensembl chr10:66,942,398...67,048,308
JBrowse link
G Rab38 RAB38, member RAS oncogene family increases expression ISO GW 4064 results in increased expression of RAB38 mRNA CTD PMID:26655953 NCBI chr 1:152,072,716...152,153,449
Ensembl chr 1:152,072,665...152,153,449
JBrowse link
G Rabggta Rab geranylgeranyltransferase subunit alpha multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA CTD PMID:30611723 NCBI chr15:34,393,419...34,400,466
Ensembl chr15:34,393,233...34,400,449
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA CTD PMID:30611723 NCBI chr 2:260,110,309...260,115,574
Ensembl chr 2:260,110,309...260,115,577
JBrowse link
G Rarres2 retinoic acid receptor responder 2 increases expression
multiple interactions
ISO GW 4064 results in increased expression of RARRES2 mRNA
GW 4064 promotes the reaction [NR1H4 protein binds to RARRES2 gene]
CTD PMID:20091679 PMID:26655953 NCBI chr 4:78,205,809...78,208,956
Ensembl chr 4:78,205,812...78,208,767
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression ISO GW 4064 results in decreased expression of RASGRP1 mRNA CTD PMID:26655953 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases phosphorylation ISO GW 4064 results in increased phosphorylation of RB1 protein CTD PMID:31437187 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbp4 retinol binding protein 4 increases expression ISO GW 4064 results in increased expression of RBP4 mRNA CTD PMID:26655953 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711
JBrowse link
G Reep6 receptor accessory protein 6 increases expression ISO GW 4064 results in increased expression of REEP6 mRNA CTD PMID:26655953 NCBI chr 7:12,240,059...12,246,814
Ensembl chr 7:12,240,060...12,246,729
JBrowse link
G Rfx5 regulatory factor X5 increases expression ISO GW 4064 results in increased expression of RFX5 mRNA CTD PMID:26655953 NCBI chr 2:196,119,054...196,128,109
Ensembl chr 2:196,120,580...196,128,095
JBrowse link
G Rhcg Rh family, C glycoprotein decreases expression ISO GW 4064 results in decreased expression of RHCG mRNA CTD PMID:26655953 NCBI chr 1:141,325,854...141,349,881
Ensembl chr 1:141,325,856...141,349,881
JBrowse link
G Rnase4 ribonuclease A family member 4 increases expression ISO GW 4064 results in increased expression of RNASE4 mRNA CTD PMID:26655953 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rnf152 ring finger protein 152 increases expression ISO GW 4064 results in increased expression of RNF152 mRNA CTD PMID:26655953 NCBI chr13:25,183,295...25,262,785
Ensembl chr13:25,186,106...25,262,469
JBrowse link
G Rpl3l ribosomal protein L3-like decreases expression ISO GW 4064 results in decreased expression of RPL3L mRNA CTD PMID:26655953 NCBI chr10:14,094,769...14,105,312
Ensembl chr10:14,094,754...14,105,308
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression ISO GW 4064 results in decreased expression of RPRM mRNA CTD PMID:26655953 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO GW 4064 results in decreased expression of RSAD2 mRNA CTD PMID:26655953 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Rtl5 retrotransposon Gag like 5 increases expression ISO GW 4064 results in increased expression of RTL5 mRNA CTD PMID:26655953 NCBI chr  X:71,956,446...71,961,013 JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 increases expression ISO GW 4064 results in increased expression of RUNX1T1 mRNA CTD PMID:26655953 NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841
JBrowse link
G Satb2 SATB homeobox 2 increases expression ISO GW 4064 results in increased expression of SATB2 mRNA CTD PMID:26655953 NCBI chr 9:63,456,877...63,642,193
Ensembl chr 9:63,456,783...63,641,400
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
increases expression
ISO [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of SCARB1 mRNA; FGF15 gene mutant form inhibits the reaction [GW 4064 results in increased expression of SCARB1 mRNA]; GW 4064 promotes the reaction [NR1H4 protein binds to SCARB1 intron] CTD PMID:22540009 PMID:30996006 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of SCD mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of SCD mRNA
CTD PMID:30611723 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scp2 sterol carrier protein 2 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of SCP2 mRNA CTD PMID:30611723 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Sema3c semaphorin 3C increases expression ISO GW 4064 results in increased expression of SEMA3C mRNA CTD PMID:26655953 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
G Sema4g semaphorin 4G increases expression ISO GW 4064 results in increased expression of SEMA4G mRNA CTD PMID:26655953 NCBI chr 1:264,738,935...264,753,399
Ensembl chr 1:264,741,911...264,753,397
JBrowse link
G Sema5b semaphorin 5B increases expression ISO GW 4064 results in increased expression of SEMA5B mRNA CTD PMID:26655953 NCBI chr11:68,304,844...68,435,109
Ensembl chr11:68,306,659...68,349,238
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression ISO GW 4064 results in decreased expression of SERPINA3N mRNA CTD PMID:26655953 NCBI chr 6:128,073,344...128,080,878
Ensembl chr 6:127,941,526...128,080,889
JBrowse link
G Serpina4 serpin family A member 4 increases expression ISO GW 4064 results in increased expression of SERPINA4-PS1 mRNA CTD PMID:26655953 NCBI chr 6:127,743,883...127,753,047
Ensembl chr 6:127,743,971...127,753,046
JBrowse link
G Serpina6 serpin family A member 6 decreases expression ISO GW 4064 results in decreased expression of SERPINA6 mRNA CTD PMID:26655953 NCBI chr 6:127,523,948...127,534,178
Ensembl chr 6:127,523,906...127,534,247
JBrowse link
G Serpinf2 serpin family F member 2 increases expression ISO GW 4064 results in increased expression of SERPINF2 mRNA CTD PMID:26655953 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Sfn stratifin increases expression ISO GW 4064 results in increased expression of SFN mRNA CTD PMID:31437187 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 increases expression ISO GW 4064 results in increased expression of SGK2 mRNA CTD PMID:26655953 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 increases expression ISO GW 4064 results in increased expression of SHANK2 mRNA CTD PMID:26655953 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shisa9 shisa family member 9 decreases expression ISO GW 4064 results in decreased expression of SHISA9 mRNA CTD PMID:26655953 NCBI chr10:2,777,675...3,072,842 JBrowse link
G Skp2 S-phase kinase associated protein 2 increases expression ISO GW 4064 results in increased expression of SKP2 mRNA CTD PMID:31437187 NCBI chr 2:58,506,146...58,534,211
Ensembl chr 2:58,506,151...58,534,211
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
decreases expression
increases expression
ISO
EXP
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in decreased expression of SLC10A1 mRNA; GW 4064 promotes the reaction [NR1H4 protein binds to SLC10A1 gene]
GW 4064 results in decreased expression of SLC10A1 mRNA
GW 4064 results in increased expression of SLC10A1 mRNA
GW 4064 results in increased expression of SLC10A1 mRNA; GW 4064 results in increased expression of SLC10A1 protein
CTD PMID:14623915 PMID:15644430 PMID:20091679 PMID:22540009 PMID:27609522 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc12a3 solute carrier family 12 member 3 decreases expression ISO GW 4064 results in decreased expression of SLC12A3 mRNA CTD PMID:26655953 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641
JBrowse link
G Slc13a1 solute carrier family 13 member 1 increases expression ISO GW 4064 results in increased expression of SLC13A1 mRNA CTD PMID:26655953 NCBI chr 4:51,121,784...51,199,477
Ensembl chr 4:51,121,123...51,199,570
JBrowse link
G Slc13a2 solute carrier family 13 member 2 increases expression ISO GW 4064 results in increased expression of SLC13A2 mRNA CTD PMID:26655953 NCBI chr10:65,664,665...65,692,046
Ensembl chr10:65,664,667...65,692,023
JBrowse link
G Slc13a3 solute carrier family 13 member 3 increases expression ISO GW 4064 results in increased expression of SLC13A3 mRNA CTD PMID:26655953 NCBI chr 3:162,084,336...162,147,398
Ensembl chr 3:162,084,315...162,147,393
JBrowse link
G Slc13a5 solute carrier family 13 member 5 decreases expression ISO GW 4064 results in decreased expression of SLC13A5 mRNA CTD PMID:26655953 NCBI chr10:58,806,581...58,835,549
Ensembl chr10:58,810,058...58,834,538
JBrowse link
G Slc16a14 solute carrier family 16, member 14 decreases expression ISO GW 4064 results in decreased expression of SLC16A14 mRNA CTD PMID:26655953 NCBI chr 9:92,503,602...92,531,163
Ensembl chr 9:92,503,597...92,530,938
JBrowse link
G Slc16a3 solute carrier family 16 member 3 decreases expression ISO GW 4064 results in decreased expression of SLC16A3 mRNA CTD PMID:26655953 NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression ISO GW 4064 results in increased expression of SLC17A1 mRNA CTD PMID:26655953 NCBI chr17:43,473,048...43,504,645 JBrowse link
G Slc17a3 solute carrier family 17 member 3 increases expression ISO GW 4064 results in increased expression of SLC17A3 mRNA CTD PMID:26655953 NCBI chr17:43,518,760...43,545,160
Ensembl chr17:43,518,655...43,543,185
JBrowse link
G Slc17a4 solute carrier family 17, member 4 increases expression ISO GW 4064 results in increased expression of SLC17A4 mRNA CTD PMID:26655953 NCBI chr17:43,452,316...43,472,192
Ensembl chr17:43,458,553...43,470,378
JBrowse link
G Slc18a1 solute carrier family 18 member A1 increases expression ISO GW 4064 results in increased expression of SLC18A1 mRNA CTD PMID:26655953 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183
JBrowse link
G Slc19a3 solute carrier family 19 member 3 increases expression ISO GW 4064 results in increased expression of SLC19A3 mRNA CTD PMID:26655953 NCBI chr 9:88,762,775...88,828,553
Ensembl chr 9:88,764,073...88,816,898
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases expression ISO GW 4064 results in increased expression of SLC22A6 mRNA CTD PMID:26655953 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases expression ISO GW 4064 results in increased expression of SLC22A8 mRNA CTD PMID:26655953 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc25a15 solute carrier family 25 member 15 increases expression ISO GW 4064 results in increased expression of SLC25A15 mRNA CTD PMID:26655953 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC25A20 mRNA CTD PMID:30611723 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to SLC25A3 gene] CTD PMID:20091679 NCBI chr 7:31,816,601...31,824,064
Ensembl chr 7:31,816,602...31,824,071
JBrowse link
G Slc25a43 solute carrier family 25, member 43 increases expression ISO GW 4064 results in increased expression of SLC25A43 mRNA CTD PMID:26655953 NCBI chr  X:123,349,836...123,384,798
Ensembl chr  X:123,350,346...123,384,846
JBrowse link
G Slc26a6 solute carrier family 26 member 6 increases expression ISO GW 4064 results in increased expression of SLC26A6 mRNA CTD PMID:26655953 NCBI chr 8:117,648,792...117,659,376
Ensembl chr 8:117,648,745...117,659,804
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA CTD PMID:30611723 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc27a2 solute carrier family 27 member 2 multiple interactions
increases expression
ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A2 mRNA
GW 4064 results in increased expression of SLC27A2 mRNA
CTD PMID:30611723 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression ISO GW 4064 results in increased expression of SLC27A5 mRNA CTD PMID:27609522 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186
JBrowse link
G Slc2a5 solute carrier family 2 member 5 increases expression ISO GW 4064 results in increased expression of SLC2A5 mRNA CTD PMID:26655953 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Slc35f3 solute carrier family 35, member F3 decreases expression ISO GW 4064 results in decreased expression of SLC35F3 mRNA CTD PMID:26655953 NCBI chr19:58,968,036...59,305,300
Ensembl chr19:59,186,673...59,304,832
JBrowse link
G Slc39a5 solute carrier family 39 member 5 increases expression ISO GW 4064 results in increased expression of SLC39A5 mRNA CTD PMID:26655953 NCBI chr 7:2,813,875...2,819,917
Ensembl chr 7:2,813,875...2,819,299
JBrowse link
G Slc3a1 solute carrier family 3 member 1 increases expression ISO GW 4064 results in increased expression of SLC3A1 mRNA CTD PMID:26655953 NCBI chr 6:8,284,937...8,318,649
Ensembl chr 6:8,284,878...8,318,674
JBrowse link
G Slc51a solute carrier family 51 subunit alpha multiple interactions
increases expression
ISO epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of SLC51A mRNA]
[GW 4064 co-treated with Dietary Fats] results in decreased expression of SLC51A mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51A mRNA]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC51A gene]
CTD PMID:20091679 PMID:22178739 PMID:26655953 PMID:27609522 PMID:28223344 NCBI chr11:71,533,078...71,547,476
Ensembl chr11:71,533,078...71,547,476
JBrowse link
G Slc51b solute carrier family 51 subunit beta increases expression
multiple interactions
ISO GW 4064 results in increased expression of SLC51B mRNA
epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of SLC51B mRNA]
[GW 4064 binds to and results in increased activity of NR1H4 protein] which results in increased expression of SLC51B mRNA; [GW 4064 co-treated with Dietary Fats] results in decreased expression of SLC51B mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SLC51B mRNA]; GW 4064 promotes the reaction [NR1H4 protein binds to SLC51B gene]
CTD PMID:20091679 PMID:22178739 PMID:22540009 PMID:23178280 PMID:26655953 PMID:27609522 PMID:28223344 NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO GW 4064 results in increased expression of SLC5A1 mRNA CTD PMID:26655953 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Slc5a9 solute carrier family 5 member 9 increases expression ISO GW 4064 results in increased expression of SLC5A9 mRNA CTD PMID:26655953 NCBI chr 5:131,836,927...131,865,218
Ensembl chr 5:131,836,934...131,860,754
JBrowse link
G Slc6a13 solute carrier family 6 member 13 increases expression ISO GW 4064 results in increased expression of SLC6A13 mRNA CTD PMID:26655953 NCBI chr 4:153,874,942...153,912,185
Ensembl chr 4:153,874,852...153,912,155
JBrowse link
G Slc7a9 solute carrier family 7 member 9 increases expression ISO GW 4064 results in increased expression of SLC7A9 mRNA CTD PMID:26655953 NCBI chr 1:91,709,034...91,738,492
Ensembl chr 1:91,716,383...91,738,494
JBrowse link
G Slc9a3 solute carrier family 9 member A3 decreases expression ISO GW 4064 results in decreased expression of SLC9A3 mRNA CTD PMID:26655953 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070
JBrowse link
G Slc9a8 solute carrier family 9 member A8 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to SLC9A8 gene] CTD PMID:20091679 NCBI chr 3:164,173,045...164,224,747
Ensembl chr 3:164,174,357...164,222,329
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression
multiple interactions
EXP GW 4064 increases expression of Slco1a4 mRNA in primary hepatocytes
GW 4064 inhibits the reaction [Ethinyl Estradiol results in decreased expression of SLCO1A2 mRNA]
GW 4064 inhibits the reaction [17alpha-ethynylestradiol decreases expression of Slco1a4 mRNA in primary hepatocytes]
CTD PMID:27090119, PMID:27090119, PMID:27090119 RGD:15090804, RGD:15090804 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases expression ISO GW 4064 results in increased expression of SLCO1B2 mRNA CTD PMID:27609522 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Smad9 SMAD family member 9 decreases expression ISO GW 4064 results in decreased expression of SMAD9 mRNA CTD PMID:26655953 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
G Smim27 small integral membrane protein 27 increases expression ISO GW 4064 results in increased expression of SMIM27 mRNA CTD PMID:26655953 NCBI chr 5:56,565,237...56,566,870 JBrowse link
G Smlr1 small leucine-rich protein 1 increases expression ISO GW 4064 results in increased expression of SMLR1 mRNA CTD PMID:26655953 NCBI chr 1:20,856,187...20,877,716
Ensembl chr 1:20,856,187...20,877,716
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD3 mRNA] CTD PMID:28223344 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SMPD4 mRNA] CTD PMID:28223344 NCBI chr11:87,522,971...87,546,687
Ensembl chr11:87,522,971...87,546,687
JBrowse link
G Snap91 synaptosome associated protein 91 decreases expression ISO GW 4064 results in decreased expression of SNAP91 mRNA CTD PMID:26655953 NCBI chr 8:94,447,558...94,564,772
Ensembl chr 8:94,447,550...94,564,525
JBrowse link
G Soat2 sterol O-acyltransferase 2 increases expression ISO GW 4064 results in increased expression of SOAT2 mRNA CTD PMID:26655953 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions
increases expression
ISO GW 4064 promotes the reaction [NR1H4 protein binds to SOD3 promoter]; SOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]; SOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]]
NR1H4 gene mutant form inhibits the reaction [GW 4064 results in increased expression of SOD3 mRNA]
CTD PMID:25496033 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sox18 SRY-box transcription factor 18 increases expression ISO GW 4064 results in increased expression of SOX18 mRNA CTD PMID:26655953 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
G Sp8 Sp8 transcription factor increases expression ISO GW 4064 results in increased expression of SP8 mRNA CTD PMID:26655953 NCBI chr 6:146,784,915...146,789,439
Ensembl chr 6:146,784,915...146,787,518
JBrowse link
G Spp2 secreted phosphoprotein 2 increases expression ISO GW 4064 results in increased expression of SPP2 mRNA CTD PMID:26655953 NCBI chr 9:95,501,512...95,509,646
Ensembl chr 9:95,501,778...95,506,365
JBrowse link
G Sprr2f small proline rich protein 2F decreases expression ISO GW 4064 results in decreased expression of SPRR2F mRNA CTD PMID:26655953 NCBI chr 2:192,604,978...192,605,208 JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA] CTD PMID:28223344 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO GW 4064 results in increased expression of SQSTM1 mRNA; GW 4064 results in increased expression of SQSTM1 protein CTD PMID:22952826 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of SREBF1 mRNA
[GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA
CTD PMID:16269825 PMID:30611723 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srl sarcalumenin increases expression ISO GW 4064 results in increased expression of SRL mRNA CTD PMID:26655953 NCBI chr10:11,240,135...11,284,325
Ensembl chr10:11,240,138...11,284,332
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 increases expression ISO GW 4064 results in increased expression of ST3GAL5 mRNA CTD PMID:26655953 NCBI chr 4:99,937,499...99,999,905
Ensembl chr 4:99,937,558...99,999,902
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 decreases expression ISO GW 4064 results in decreased expression of ST8SIA6 mRNA CTD PMID:26655953 NCBI chr17:80,960,785...81,002,830
Ensembl chr17:80,960,785...81,002,838
JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to STAT2 gene] CTD PMID:20091679 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO GW 4064 results in increased expression of STC2 mRNA CTD PMID:26655953 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Stk32a serine/threonine kinase 32A decreases expression ISO GW 4064 results in decreased expression of STK32A mRNA CTD PMID:26655953 NCBI chr18:37,597,305...37,706,884
Ensembl chr18:37,597,156...37,710,306
JBrowse link
G Stkld1 serine/threonine kinase-like domain containing 1 increases expression ISO GW 4064 results in increased expression of STKLD1 mRNA CTD PMID:26655953 NCBI chr 3:5,481,524...5,500,568
Ensembl chr 3:5,481,522...5,500,583
JBrowse link
G Stra8 stimulated by retinoic acid 8 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of STRA8 mRNA
bisphenol A inhibits the reaction [GW 4064 results in decreased expression of STRA8 mRNA]; GW 4064 inhibits the reaction [bisphenol A results in decreased expression of STRA8 mRNA]; GW 4064 inhibits the reaction [Stigmasterol results in decreased expression of STRA8 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of STRA8 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of STRA8 mRNA]
CTD PMID:30245210 NCBI chr 4:62,447,724...62,474,802
Ensembl chr 4:62,457,694...62,473,360
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression ISO GW 4064 results in decreased expression of SULT2A1 mRNA CTD PMID:16946559 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to SUMO3 gene] CTD PMID:20091679 NCBI chr20:11,726,488...11,737,050
Ensembl chr20:11,726,497...11,737,050
JBrowse link
G Sun3 Sad1 and UNC84 domain containing 3 increases expression ISO GW 4064 results in increased expression of SUN3 mRNA CTD PMID:26655953 NCBI chr14:89,215,386...89,253,585
Ensembl chr14:89,215,703...89,238,094
JBrowse link
G Susd3 sushi domain containing 3 increases expression ISO GW 4064 results in increased expression of SUSD3 mRNA CTD PMID:26655953 NCBI chr17:15,814,132...15,830,328
Ensembl chr17:15,814,132...15,830,328
JBrowse link
G Synm synemin increases expression ISO GW 4064 results in increased expression of SYNM mRNA CTD PMID:26655953 NCBI chr 1:128,692,112...128,722,048
Ensembl chr 1:128,692,112...128,722,048
JBrowse link
G Syt9 synaptotagmin 9 increases expression ISO GW 4064 results in increased expression of SYT9 mRNA CTD PMID:26655953 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link
G Sytl3 synaptotagmin-like 3 increases expression ISO GW 4064 results in increased expression of SYTL3 mRNA CTD PMID:26655953 NCBI chr 1:47,216,988...47,287,372
Ensembl chr 1:47,231,093...47,287,371
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO GW 4064 results in increased expression of TAC1 mRNA CTD PMID:26655953 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tbpl2 TATA box binding protein-like 2 decreases expression ISO GW 4064 results in decreased expression of TBPL2 mRNA CTD PMID:26655953 NCBI chr 3:1,095,883...1,116,677
Ensembl chr 3:1,095,883...1,116,677
JBrowse link
G Tbx3 T-box transcription factor 3 increases expression ISO GW 4064 results in increased expression of TBX3 mRNA CTD PMID:31437187 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions ISO [GW 4064 co-treated with Oleic Acid] results in decreased expression of TECR mRNA CTD PMID:30611723 NCBI chr19:24,705,478...24,732,024
Ensembl chr19:24,705,481...24,732,024
JBrowse link
G Tf transferrin increases expression ISO GW 4064 results in increased expression of TRF mRNA CTD PMID:26655953 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfap2e transcription factor AP-2 epsilon multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to TFAP2E gene] CTD PMID:20091679 NCBI chr 5:144,740,950...144,761,787
Ensembl chr 5:144,740,956...144,761,787
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO GW 4064 results in increased expression of TGFB3 mRNA CTD PMID:31437187 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbi transforming growth factor, beta induced increases expression ISO GW 4064 results in increased expression of TGFBI mRNA CTD PMID:26655953 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Tkfc triokinase and FMN cyclase increases expression ISO GW 4064 results in increased expression of TKFC mRNA CTD PMID:26655953 NCBI chr 1:226,642,901...226,657,698
Ensembl chr 1:226,644,200...226,657,408
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to TLR3 gene] CTD PMID:20091679 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 increases expression ISO GW 4064 results in increased expression of TM4SF4 mRNA CTD PMID:26655953 NCBI chr 2:147,532,032...147,547,254
Ensembl chr 2:147,496,229...147,547,252
JBrowse link
G Tm6sf2 transmembrane 6 superfamily member 2 increases expression ISO GW 4064 results in increased expression of TM6SF2 mRNA CTD PMID:26655953 NCBI chr16:21,092,483...21,099,695
Ensembl chr16:21,092,308...21,099,878
JBrowse link
G Tmed6 transmembrane p24 trafficking protein 6 decreases expression ISO GW 4064 results in decreased expression of TMED6 mRNA CTD PMID:26655953 NCBI chr19:39,261,841...39,267,928
Ensembl chr19:39,261,841...39,267,928
JBrowse link
G Tmem174 transmembrane protein 174 increases expression ISO GW 4064 results in increased expression of TMEM174 mRNA CTD PMID:26655953 NCBI chr 2:28,748,706...28,750,237
Ensembl chr 2:28,748,707...28,750,237
JBrowse link
G Tmem179 transmembrane protein 179 increases expression ISO GW 4064 results in increased expression of TMEM179 mRNA CTD PMID:26655953 NCBI chr 6:137,073,684...137,084,739
Ensembl chr 6:137,073,685...137,084,739
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO GW 4064 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; GW 4064 inhibits the reaction [TNF protein results in increased expression of NR1H4 mRNA]
GW 4064 results in decreased expression of TNF mRNA
CTD PMID:21242261 PMID:23371517 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 decreases expression EXP GW 4064 results in decreased expression of TNFRSF10B mRNA CTD PMID:14623915 NCBI chr 1:216,808,642...216,829,361
Ensembl chr 1:216,808,632...216,828,651
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO GW 4064 results in increased expression of TNFRSF9 mRNA CTD PMID:26655953 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810
JBrowse link
G Tnfsf15 TNF superfamily member 15 increases expression ISO GW 4064 results in increased expression of TNFSF15 mRNA CTD PMID:26655953 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO GW 4064 results in decreased expression of TP53 mRNA; GW 4064 results in decreased expression of TP53 protein CTD PMID:28496032 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trim54 tripartite motif-containing 54 increases expression ISO GW 4064 results in increased expression of TRIM54 mRNA CTD PMID:26655953 NCBI chr 6:26,603,364...26,623,950
Ensembl chr 6:26,603,369...26,624,092
JBrowse link
G Triml2 tripartite motif family-like 2 decreases expression ISO GW 4064 results in decreased expression of TRIML2 mRNA CTD PMID:26655953 NCBI chr16:52,116,975...52,127,591
Ensembl chr16:52,116,975...52,127,591
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 decreases expression ISO GW 4064 results in decreased expression of TRPC3 mRNA CTD PMID:26655953 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496
JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to TRPM7 gene] CTD PMID:20091679 NCBI chr 3:119,258,189...119,347,084
Ensembl chr 3:119,259,467...119,330,345
JBrowse link
G Tslp thymic stromal lymphopoietin decreases expression ISO GW 4064 results in decreased expression of TSLP mRNA CTD PMID:26655953 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Ttbk1 tau tubulin kinase 1 increases expression ISO GW 4064 results in increased expression of TTBK1 mRNA CTD PMID:26655953 NCBI chr 9:16,862,305...16,899,399
Ensembl chr 9:16,862,248...16,902,199
JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 increases expression ISO GW 4064 results in increased expression of TTC36 mRNA CTD PMID:26655953 NCBI chr 8:49,106,374...49,109,981
Ensembl chr 8:49,106,374...49,109,981
JBrowse link
G Ttk Ttk protein kinase increases expression ISO GW 4064 results in increased expression of TTK mRNA CTD PMID:31437187 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Txk TXK tyrosine kinase decreases expression ISO GW 4064 results in decreased expression of TXK mRNA CTD PMID:26655953 NCBI chr14:38,029,809...38,085,822
Ensembl chr14:38,030,189...38,085,919
JBrowse link
G Ubd ubiquitin D increases expression ISO GW 4064 results in increased expression of UBD mRNA CTD PMID:26655953 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Ube2ql1 ubiquitin-conjugating enzyme E2Q family-like 1 decreases expression ISO GW 4064 results in decreased expression of UBE2QL1 mRNA CTD PMID:26655953 NCBI chr 1:36,185,916...36,226,276
Ensembl chr 1:36,185,916...36,226,276
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO [GW 4064 results in increased activity of NR1H4 protein] which results in increased expression of UGT1A3 mRNA CTD PMID:20189675 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Unc13c unc-13 homolog C increases expression ISO GW 4064 results in increased expression of UNC13C mRNA CTD PMID:26655953 NCBI chr 8:80,202,736...80,656,363
Ensembl chr 8:80,203,609...80,631,926
JBrowse link
G Unc5cl unc-5 family C-terminal like increases expression ISO GW 4064 results in increased expression of UNC5CL mRNA CTD PMID:26655953 NCBI chr 9:14,494,080...14,510,302
Ensembl chr 9:14,491,584...14,508,235
JBrowse link
G Uroc1 urocanate hydratase 1 increases expression ISO GW 4064 results in increased expression of UROC1 mRNA CTD PMID:26655953 NCBI chr 4:122,244,744...122,276,357
Ensembl chr 4:122,244,711...122,276,361
JBrowse link
G Usp18 ubiquitin specific peptidase 18 decreases expression ISO GW 4064 results in decreased expression of USP18 mRNA CTD PMID:26655953 NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO GW 4064 results in increased expression of VCAM1 mRNA CTD PMID:16582018 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of VDAC1 mRNA] CTD PMID:28223344 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vegfd vascular endothelial growth factor D decreases expression ISO GW 4064 results in decreased expression of VEGFD mRNA CTD PMID:26655953 NCBI chr  X:31,816,480...31,852,239
Ensembl chr  X:31,816,436...31,851,715
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 multiple interactions
increases expression
ISO alitretinoin inhibits the reaction [GW 4064 results in increased expression of VIPR1] CTD PMID:16037943 NCBI chr 8:130,283,453...130,313,431 JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 multiple interactions ISO GW 4064 promotes the reaction [NR1H4 protein binds to VKORC1 gene] CTD PMID:20091679 NCBI chr 1:199,338,785...199,341,306
Ensembl chr 1:199,337,138...199,341,302
JBrowse link
G Vnn1 vanin 1 increases expression ISO GW 4064 results in increased expression of VNN1 mRNA CTD PMID:26655953 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 decreases expression ISO GW 4064 results in decreased expression of VSIG4 mRNA CTD PMID:26655953 NCBI chr  X:65,370,851...65,400,298
Ensembl chr  X:65,370,851...65,400,298
JBrowse link
G Vwce von Willebrand factor C and EGF domains increases expression ISO GW 4064 results in increased expression of VWCE mRNA CTD PMID:26655953 NCBI chr 1:226,687,258...226,717,989
Ensembl chr 1:226,687,258...226,710,897
JBrowse link
G Wdr7 WD repeat domain 7 decreases expression ISO GW 4064 results in decreased expression of WDR7 mRNA CTD PMID:26655953 NCBI chr18:59,096,636...59,396,312
Ensembl chr18:59,096,643...59,396,318
JBrowse link
G Wdr86 WD repeat domain 86 decreases expression ISO GW 4064 results in decreased expression of WDR86 mRNA CTD PMID:26655953 NCBI chr 4:6,942,415...6,948,912
Ensembl chr 4:6,931,495...6,948,243
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression ISO GW 4064 results in increased expression of WEE1 mRNA CTD PMID:31437187 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Wscd2 WSC domain containing 2 decreases expression ISO GW 4064 results in decreased expression of WSCD2 mRNA CTD PMID:26655953 NCBI chr12:48,814,840...48,861,823
Ensembl chr12:48,817,320...48,857,724
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 increases expression ISO GW 4064 results in increased expression of XPNPEP2 mRNA CTD PMID:26655953 NCBI chr  X:134,940,656...134,969,874
Ensembl chr  X:134,940,615...134,969,996
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression
multiple interactions
ISO GW 4064 results in decreased expression of ZBTB16 mRNA
bisphenol A inhibits the reaction [GW 4064 results in decreased expression of ZBTB16 mRNA]; NR1H4 gene mutant form inhibits the reaction [GW 4064 results in decreased expression of ZBTB16 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of ZBTB16 mRNA]
CTD PMID:26655953 PMID:30245210 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953
JBrowse link
G Zdhhc19 zinc finger DHHC-type palmitoyltransferase 19 increases expression ISO GW 4064 results in increased expression of ZDHHC19 mRNA CTD PMID:26655953 NCBI chr11:71,490,346...71,522,959
Ensembl chr11:71,511,715...71,523,267
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    chemical entity 19883
      atom 19881
        nonmetal atom 19760
          carbon atom 19668
            organic molecular entity 19668
              olefinic compound 14849
                stilbenoid 5643
                  GW 4064 580
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic molecule 19596
                              organic cyclic compound 19407
                                organic aromatic compound 19233
                                  stilbenoid 5643
                                    GW 4064 580
paths to the root