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G |
C6h14orf28 |
similar to human chromosome 14 open reading frame 28 |
multiple interactions |
ISO |
GW 1929 promotes the reaction [C14ORF28 protein binds to PPARG protein] |
CTD |
PMID:32407875 |
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NCBI chr 6:82,965,304...82,973,942
Ensembl chr 6:82,965,328...82,972,558
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [tetrabromobisphenol A results in increased activity of CASP3 protein] |
CTD |
PMID:24132472 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
decreases response to substance |
ISO |
GW 1929 results in decreased susceptibility to CCL5 protein |
CTD |
PMID:18158351 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; GW 1929 inhibits the reaction [VEGFA protein results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:20032081 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
decreases response to substance multiple interactions |
ISO |
GW 1929 results in decreased susceptibility to CXCL12 protein GW 1929 inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein] |
CTD |
PMID:18158351 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Efna1 |
ephrin A1 |
increases expression multiple interactions |
EXP |
GW 1929 results in increased expression of EFNA1 mRNA Mercaptopurine promotes the reaction [GW 1929 results in increased expression of EFNA1 mRNA] |
CTD |
PMID:27435855 |
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NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions |
ISO |
[GW 1929 binds to and results in increased activity of PPARG protein] promotes the reaction [TNF protein results in decreased susceptibility to FSHB protein] |
CTD |
PMID:21734263 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Grk2 |
G protein-coupled receptor kinase 2 |
decreases expression |
EXP |
GW 1929 results in decreased expression of GRK2 mRNA |
CTD |
PMID:19420904 |
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NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; GW 1929 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA]; GW 1929 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA] |
CTD |
PMID:12847270 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [IFNG protein results in increased expression of IRF1 mRNA] |
CTD |
PMID:12847270 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [GW 1929 results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [GW 1929 results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:12083801 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [GW 1929 results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [GW 1929 results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:12083801 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
GW 1929 promotes the reaction [NCOA2 protein binds to PPARG protein] |
CTD |
PMID:32407875 |
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NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Ncoa6 |
nuclear receptor coactivator 6 |
multiple interactions |
ISO |
GW 1929 promotes the reaction [NCOA6 protein binds to PPARG protein] |
CTD |
PMID:32407875 |
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NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [[IFNG protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; GW 1929 inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA] |
CTD |
PMID:12847270 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
multiple interactions affects localization |
EXP |
[GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 mRNA; [GW 1929 co-treated with Mercaptopurine] results in increased expression of NR4A2 protein GW 1929 affects the localization of NR4A2 protein |
CTD |
PMID:27435855 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nrip1 |
nuclear receptor interacting protein 1 |
multiple interactions |
ISO |
GW 1929 promotes the reaction [NRIP1 protein binds to PPARG protein] |
CTD |
PMID:32407875 |
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NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases activity affects binding multiple interactions increases expression |
ISO EXP |
GW 1929 results in increased activity of PPARG protein GW 1929 binds to PPARG protein [GW 1929 binds to and results in increased activity of PPARG protein] promotes the reaction [TNF protein results in decreased susceptibility to FSHB protein]; butylbenzyl phthalate inhibits the reaction [GW 1929 binds to PPARG protein]; GW 1929 inhibits the reaction [GW 1929 binds to PPARG protein]; GW 1929 inhibits the reaction [Melatonin results in increased expression of PPARG protein]; GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; GW 1929 promotes the reaction [C14ORF28 protein binds to PPARG protein]; GW 1929 promotes the reaction [NCOA2 protein binds to PPARG protein]; GW 1929 promotes the reaction [NCOA6 protein binds to PPARG protein]; GW 1929 promotes the reaction [NRIP1 protein binds to PPARG protein]; GW 1929 promotes the reaction [PPARGC1A protein binds to PPARG protein]; GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]; Pioglitazone inhibits the reaction [GW 1929 binds to PPARG protein]; tributyltin inhibits the reaction [GW 1929 binds to PPARG protein]; ZNF366 protein promotes the reaction [GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]] GW 1929 results in increased expression of PPARG mRNA 4-chloro-N-(2-((5-trifluoromethyl-2-pyridyl)sulfonyl)ethyl)benzamide inhibits the reaction [GW 1929 results in increased expression of PPARG mRNA]; GW 1929 binds to and results in increased activity of PPARG protein; GW 1929 inhibits the reaction [PPARG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]; GW 1929 inhibits the reaction [tetrabromobisphenol A results in decreased expression of PPARG protein] |
CTD |
PMID:12847270 PMID:18292206 PMID:19420904 PMID:20008677 PMID:20516370 PMID:21543282 PMID:21734263 PMID:24132472 PMID:29734669 PMID:31016361 PMID:32407875 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
GW 1929 promotes the reaction [PPARGC1A protein binds to PPARG protein] |
CTD |
PMID:32407875 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prnp |
prion protein |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [Melatonin results in increased expression of PRNP protein]; GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PRNP protein] |
CTD |
PMID:29734669 |
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NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; GW 1929 inhibits the reaction [VEGFA protein results in increased expression of and results in increased activity of PTGS2 protein]; GW 1929 inhibits the reaction [VEGFA protein results in increased expression of PTGS2 mRNA] |
CTD |
PMID:20032081 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
increases activity |
ISO |
GW 1929 results in increased activity of RAF1 protein |
CTD |
PMID:12083801 |
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NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]; ZNF366 protein promotes the reaction [GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]] |
CTD |
PMID:20008677 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
EXP |
[GW 1929 co-treated with Mercaptopurine] inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]; GW 1929 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] |
CTD |
PMID:27435855 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
[GW 1929 binds to and results in increased activity of PPARG protein] promotes the reaction [TNF protein results in decreased susceptibility to FSHB protein] |
CTD |
PMID:21734263 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
GW 1929 inhibits the reaction [VEGFA protein results in increased expression of and results in increased activity of PTGS2 protein]; GW 1929 inhibits the reaction [VEGFA protein results in increased expression of PTGS2 mRNA]; GW 1929 inhibits the reaction [VEGFA protein results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:20032081 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Zfp366 |
zinc finger protein 366 |
multiple interactions |
ISO |
ZNF366 protein promotes the reaction [GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]] |
CTD |
PMID:20008677 |
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NCBI chr 2:30,578,552...30,640,546
Ensembl chr 2:30,578,715...30,642,182
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