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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tropolone
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Accession:CHEBI:79966 term browser browse the term
Definition:A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii.
Synonyms:exact_synonym: 2-hydroxycyclohepta-2,4,6-trien-1-one
 related_synonym: 2-hydroxy-2,4,6-cycloheptatrien-1-one;   2-hydroxycyclohepta-2,4,6-trienone;   2-hydroxytropone;   Formula=C7H6O2;   InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9);   InChIKey=MDYOLVRUBBJPFM-UHFFFAOYSA-N;   SMILES=OC1=CC=CC=CC1=O;   purpurocatechol
 xref: CAS:533-75-5;   KEGG:C15474
 xref_mesh: MESH:D014334
 xref: MetaCyc:CPD-7024;   PDBeChem:0TR;   PMID:11561410;   PMID:1847521;   PMID:21598903;   PMID:27002128;   PMID:27908108;   PMID:28389830;   PMID:28661582;   PMID:29589436;   PMID:30549082;   PMID:30677202;   PMID:31452043;   PMID:31820778;   PMID:31907180;   Reaxys:1904978;   Wikipedia:Tropolone


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tropolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase decreases activity EXP Tropolone results in decreased activity of COMT protein CTD PMID:10064789 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      application 19467
        pesticide 16973
          fungicide 10991
            tropolone 1
              3,7-dihydroxytropolone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18725
                              organic divalent group 18716
                                organodiyl group 18716
                                  carbonyl group 18664
                                    carbonyl compound 18664
                                      ketone 16925
                                        oxyketone 8657
                                          alpha-oxyketone 8657
                                            alpha-hydroxy ketone 8657
                                              tropolone 1
                                                3,7-dihydroxytropolone 0
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