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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tropolone
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Accession:CHEBI:79966 term browser browse the term
Definition:A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii.
Synonyms:exact_synonym: 2-hydroxycyclohepta-2,4,6-trien-1-one
 related_synonym: 2-hydroxy-2,4,6-cycloheptatrien-1-one;   2-hydroxycyclohepta-2,4,6-trienone;   2-hydroxytropone;   Formula=C7H6O2;   InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9);   InChIKey=MDYOLVRUBBJPFM-UHFFFAOYSA-N;   SMILES=OC1=CC=CC=CC1=O;   purpurocatechol
 xref: CAS:533-75-5;   KEGG:C15474
 xref_mesh: MESH:D014334
 xref: MetaCyc:CPD-7024;   PDBeChem:0TR;   PMID:11561410;   PMID:1847521;   PMID:21598903;   PMID:27002128;   PMID:27908108;   PMID:28389830;   PMID:28661582;   PMID:29589436;   PMID:30549082;   PMID:30677202;   PMID:31452043;   PMID:31820778;   PMID:31907180;   Reaxys:1904978;   Wikipedia:Tropolone


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tropolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase decreases activity EXP Tropolone results in decreased activity of COMT protein CTD PMID:10064789 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    role 19837
      application 19682
        pesticide 18068
          fungicide 14030
            tropolone 1
              3,7-dihydroxytropolone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    main group molecular entity 19803
                      s-block molecular entity 19638
                        hydrogen molecular entity 19620
                          hydrides 19141
                            organic hydride 18692
                              organic fundamental parent 18692
                                hydrocarbon 18446
                                  olefin 8924
                                    cyclic olefin 421
                                      monocyclic olefin 419
                                        cycloalkatriene 5
                                          cycloheptatriene 5
                                            cyclohepta-1,3,5-triene 5
                                              tropolone 1
                                                3,7-dihydroxytropolone 0
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