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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tropolone
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Accession:CHEBI:79966 term browser browse the term
Definition:A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii.
Synonyms:exact_synonym: 2-hydroxycyclohepta-2,4,6-trien-1-one
 related_synonym: 2-hydroxy-2,4,6-cycloheptatrien-1-one;   2-hydroxycyclohepta-2,4,6-trienone;   2-hydroxytropone;   Formula=C7H6O2;   InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9);   InChIKey=MDYOLVRUBBJPFM-UHFFFAOYSA-N;   SMILES=OC1=CC=CC=CC1=O;   purpurocatechol
 xref: CAS:533-75-5;   KEGG:C15474
 xref_mesh: MESH:D014334
 xref: MetaCyc:CPD-7024;   PDBeChem:0TR;   PMID:11561410;   PMID:1847521;   PMID:21598903;   PMID:27002128;   PMID:27908108;   PMID:28389830;   PMID:28661582;   PMID:29589436;   PMID:30549082;   PMID:30677202;   PMID:31452043;   PMID:31820778;   PMID:31907180;   Reaxys:1904978;   Wikipedia:Tropolone


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tropolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase decreases activity EXP Tropolone results in decreased activity of COMT protein CTD PMID:10064789 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    role 19851
      application 19687
        pesticide 17849
          fungicide 13169
            tropolone 1
              3,7-dihydroxytropolone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic group 18962
                              organic divalent group 18943
                                organodiyl group 18915
                                  carbonyl group 18869
                                    carbonyl compound 18869
                                      ketone 17170
                                        oxyketone 8832
                                          alpha-oxyketone 8837
                                            alpha-hydroxy ketone 8832
                                              tropolone 1
                                                3,7-dihydroxytropolone 0
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