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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tropolone
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Accession:CHEBI:79966 term browser browse the term
Definition:A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii.
Synonyms:exact_synonym: 2-hydroxycyclohepta-2,4,6-trien-1-one
 related_synonym: 2-hydroxy-2,4,6-cycloheptatrien-1-one;   2-hydroxycyclohepta-2,4,6-trienone;   2-hydroxytropone;   Formula=C7H6O2;   InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9);   InChIKey=MDYOLVRUBBJPFM-UHFFFAOYSA-N;   SMILES=OC1=CC=CC=CC1=O;   purpurocatechol
 xref: CAS:533-75-5;   KEGG:C15474
 xref_mesh: MESH:D014334
 xref: MetaCyc:CPD-7024;   PDBeChem:0TR;   PMID:11561410;   PMID:1847521;   PMID:21598903;   PMID:27002128;   PMID:27908108;   PMID:28389830;   PMID:28661582;   PMID:29589436;   PMID:30549082;   PMID:30677202;   PMID:31452043;   PMID:31820778;   PMID:31907180;   Reaxys:1904978;   Wikipedia:Tropolone


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tropolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase decreases activity EXP Tropolone results in decreased activity of COMT protein CTD PMID:10064789 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pesticide 16263
          fungicide 10307
            tropolone 1
              3,7-dihydroxytropolone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      ketone 16140
                                        oxyketone 8629
                                          alpha-oxyketone 8629
                                            alpha-hydroxy ketone 8629
                                              tropolone 1
                                                3,7-dihydroxytropolone 0
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