Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:GYKI 52466
go back to main search page
Accession:CHEBI:79560 term browser browse the term
Definition:A benzodiazepine that has formula C17H15N3O2.
Synonyms:related_synonym: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine;   Formula=C17H15N3O2;   InChI=1S/C17H15N3O2/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11/h2-5,7-8H,6,9,18H2,1H3;   InChIKey=LFBZZHVSGAHQPP-UHFFFAOYSA-N;   SMILES=CC1=NN=C(c2ccc(N)cc2)c2cc3OCOc3cc2C1
 xref: CAS:102771-26-6;   KEGG:C15040;   LINCS:LSM-2530
 xref_mesh: MESH:C061950



show annotations for term's descendants           Sort by:
GYKI 52466 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP GYKI 52466 inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in increased phosphorylation of CREB1 protein] CTD PMID:14622123 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein] CTD PMID:16686654 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        biophysical role 14052
          membrane transport modulator 13895
            GABA modulator 5113
              benzodiazepine 911
                GYKI 52466 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19730
                        carbon atom 19727
                          organic molecular entity 19727
                            organic molecule 19680
                              organic cyclic compound 19492
                                organic heterocyclic compound 18854
                                  organonitrogen heterocyclic compound 18150
                                    benzodiazepine 911
                                      GYKI 52466 2
paths to the root