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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:GYKI 52466
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Accession:CHEBI:79560 term browser browse the term
Definition:A benzodiazepine that has formula C17H15N3O2.
Synonyms:related_synonym: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine;   Formula=C17H15N3O2;   InChI=1S/C17H15N3O2/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11/h2-5,7-8H,6,9,18H2,1H3;   InChIKey=LFBZZHVSGAHQPP-UHFFFAOYSA-N;   SMILES=CC1=NN=C(c2ccc(N)cc2)c2cc3OCOc3cc2C1
 xref: CAS:102771-26-6;   KEGG:C15040;   LINCS:LSM-2530
 xref_mesh: MESH:C061950


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GYKI 52466 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP GYKI 52466 inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid results in increased phosphorylation of CREB1 protein] CTD PMID:14622123 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO GYKI 52466 inhibits the reaction [[Kainic Acid co-treated with dihydroxyethyldithiocarbamate] results in increased expression of HSPA1A protein] CTD PMID:16686654 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      biological role 19902
        biophysical role 14077
          membrane transport modulator 13914
            GABA modulator 5122
              benzodiazepine 924
                GYKI 52466 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            organic molecule 19764
                              organic cyclic compound 19553
                                organic heterocyclic compound 18905
                                  organonitrogen heterocyclic compound 18179
                                    benzodiazepine 924
                                      GYKI 52466 2
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