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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pemoline
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Accession:CHEBI:7953 term browser browse the term
Definition:A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Synonyms:exact_synonym: 2-amino-5-phenyl-1,3-oxazol-4(5H)-one
 related_synonym: 2-Amino-5-phenyl-4(5H)-oxazolone;   2-imino-4-keto-5-phenyltetrahydrooxazole;   5-phenyl-2-imino-4-oxazolidinone;   5-phenyl-2-imino-4-oxooxazolidine;   5-phenylisohydantion;   Azoxodon;   Betanamin;   Cylert;   Dantromin;   Deltamine;   Formula=C9H8N2O2;   Hyton;   InChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12);   InChIKey=NRNCYVBFPDDJNE-UHFFFAOYSA-N;   Myamin;   Nitan;   Notair;   SMILES=NC1=NC(=O)C(O1)c1ccccc1;   pemolina;   pemolinum;   pheniminooxazolidinone;   phenylisohydantoin;   phenylpseudohydantoin
 xref: CAS:2152-34-3;   DrugBank:DB01230;   Drug_Central:2075;   KEGG:C07899;   KEGG:D00744;   LINCS:LSM-5159;   PMID:11216184;   PMID:2210262;   PMID:2303976;   PMID:2388127;   PMID:4021028;   PMID:641739;   PMID:772696;   Reaxys:151559;   Wikipedia:Pemoline



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Path 1
Term Annotations click to browse term
  CHEBI ontology 21811
    role 21791
      application 21299
        pharmaceutical 20771
          drug 20771
            central nervous system drug 17209
              central nervous system stimulant 6897
                pemoline 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21811
    subatomic particle 21797
      composite particle 21797
        hadron 21797
          baryon 21797
            nucleon 21797
              atomic nucleus 21797
                atom 21797
                  main group element atom 21716
                    p-block element atom 21716
                      carbon group element atom 21530
                        carbon atom 21428
                          organic molecular entity 21428
                            organic molecule 21327
                              organic cyclic compound 20918
                                organic heterocyclic compound 19962
                                  heteroarene 16991
                                    monocyclic heteroarene 13675
                                      azole 12978
                                        oxazole 3631
                                          1,3-oxazoles 790
                                            pemoline 0
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