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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:patchouli alcohol
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Accession:CHEBI:7940 term browser browse the term
Definition:A carbotricyclic compound and sesquiterpenoid tertiary alcohol that is tricyclo[5.3.1.0(3,8)]undecan-3-ol which is substituted at positions 2, 2, 6 and 8 by methyl groups (the 1R,3R,6S,7S,8S-diastereoisomer).
Synonyms:exact_synonym: (1R,4S,4aS,6R,8aS)-4,8a,9,9-tetramethyloctahydro-1,6-methanonaphthalen-1(2H)-ol
 related_synonym: (-)-(1R,3R,6S,7S,8S)-2,2,6,8-tetramethyltricyclo[5.3.1.0(3,8)]undecan-3-ol;   Formula=C15H26O;   InChI=1S/C15H26O/c1-10-5-8-15(16)13(2,3)11-6-7-14(15,4)12(10)9-11/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m0/s1;   InChIKey=GGHMUJBZYLPWFD-CUZKYEQNSA-N;   SMILES=[H][C@@]12CC[C@@]3(C)[C@@]([H])(C1)[C@@H](C)CC[C@@]3(O)C2(C)C;   [1R-(1alpha,4beta,4aalpha,6beta,8aalpha)]-octahydro-4,8a,9,9-tetramethyl-1,6-methano-1(2H)-naphthol;   patchoulanol;   patchouli camphor;   patchoulic alcohol;   patchoulol
 xref: CAS:5986-55-0;   KEGG:C09705;   KNApSAcK:C00003168
 xref_mesh: MESH:C052983
 xref: MetaCyc:CPD-11399;   PMID:20148554;   PMID:3038029;   Reaxys:5730219


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patchouli alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP patchouli alcohol inhibits the reaction [Ethanol results in decreased activity of CAT protein] CTD PMID:25168850 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP patchouli alcohol inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:25168850 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]
patchouli alcohol inhibits the reaction [Ethanol results in increased expression of IL6 protein]		 CTD PMID:23348408 PMID:25168850 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK1 protein modified form] CTD PMID:23348408 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK3 protein modified form] CTD PMID:23348408 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]		 CTD PMID:23348408 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:23348408 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP patchouli alcohol inhibits the reaction [Indomethacin results in decreased expression of PTGS1 mRNA] CTD PMID:25168850 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP patchouli alcohol inhibits the reaction [Indomethacin results in decreased expression of PTGS2 mRNA] CTD PMID:25168850 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO patchouli alcohol inhibits the reaction [TNF protein affects the localization of RELA protein]
patchouli alcohol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]		 CTD PMID:23348408 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 patchouli alcohol inhibits the reaction [TNF protein affects the localization of RELA protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK1 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK3 protein modified form]
patchouli alcohol inhibits the reaction [Ethanol results in increased expression of TNF protein]		 CTD PMID:23348408 PMID:25168850 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    chemical entity 19829
      atom 19829
        nonmetal atom 19767
          carbon atom 19724
            organic molecular entity 19724
              isoprenoid 14029
                terpenoid 13728
                  sesquiterpenoid 3272
                    patchouli alcohol 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    main group molecular entity 19779
                      s-block molecular entity 19617
                        hydrogen molecular entity 19604
                          hydrides 19102
                            organic hydride 18674
                              organic fundamental parent 18674
                                hydrocarbon 18410
                                  terpene 14029
                                    sesquiterpene 3272
                                      sesquiterpenoid 3272
                                        patchouli alcohol 11
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