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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:patchouli alcohol
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Accession:CHEBI:7940 term browser browse the term
Definition:A carbotricyclic compound and sesquiterpenoid tertiary alcohol that is tricyclo[5.3.1.0(3,8)]undecan-3-ol which is substituted at positions 2, 2, 6 and 8 by methyl groups (the 1R,3R,6S,7S,8S-diastereoisomer).
Synonyms:exact_synonym: (1R,4S,4aS,6R,8aS)-4,8a,9,9-tetramethyloctahydro-1,6-methanonaphthalen-1(2H)-ol
 related_synonym: (-)-(1R,3R,6S,7S,8S)-2,2,6,8-tetramethyltricyclo[5.3.1.0(3,8)]undecan-3-ol;   Formula=C15H26O;   InChI=1S/C15H26O/c1-10-5-8-15(16)13(2,3)11-6-7-14(15,4)12(10)9-11/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m0/s1;   InChIKey=GGHMUJBZYLPWFD-CUZKYEQNSA-N;   SMILES=[H][C@@]12CC[C@@]3(C)[C@@]([H])(C1)[C@@H](C)CC[C@@]3(O)C2(C)C;   [1R-(1alpha,4beta,4aalpha,6beta,8aalpha)]-octahydro-4,8a,9,9-tetramethyl-1,6-methano-1(2H)-naphthol;   patchoulanol;   patchouli camphor;   patchoulic alcohol;   patchoulol
 xref: CAS:5986-55-0;   KEGG:C09705;   KNApSAcK:C00003168
 xref_mesh: MESH:C052983
 xref: MetaCyc:CPD-11399;   PMID:20148554;   PMID:3038029;   Reaxys:5730219


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patchouli alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP patchouli alcohol inhibits the reaction [Ethanol results in decreased activity of CAT protein] CTD PMID:25168850 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Il10 interleukin 10 multiple interactions EXP patchouli alcohol inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:25168850 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
patchouli alcohol inhibits the reaction [Ethanol results in increased expression of IL6 protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]
CTD PMID:23348408 PMID:25168850 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK1 protein modified form] CTD PMID:23348408 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK3 protein modified form] CTD PMID:23348408 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]
CTD PMID:23348408 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:23348408 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP patchouli alcohol inhibits the reaction [Indomethacin results in decreased expression of PTGS1 mRNA] CTD PMID:25168850 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP patchouli alcohol inhibits the reaction [Indomethacin results in decreased expression of PTGS2 mRNA] CTD PMID:25168850 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO patchouli alcohol inhibits the reaction [TNF protein affects the localization of RELA protein]
patchouli alcohol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD PMID:23348408 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
patchouli alcohol inhibits the reaction [TNF protein affects the localization of RELA protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
patchouli alcohol inhibits the reaction [Ethanol results in increased expression of TNF protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK1 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK3 protein modified form]
CTD PMID:23348408 PMID:25168850 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

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  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          carbon atom 19630
            organic molecular entity 19630
              isoprenoid 12711
                terpenoid 12280
                  sesquiterpenoid 2727
                    patchouli alcohol 11
Path 2
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  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            organic hydride 18353
                              organic fundamental parent 18353
                                hydrocarbon 18066
                                  terpene 12711
                                    sesquiterpene 2727
                                      sesquiterpenoid 2727
                                        patchouli alcohol 11
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