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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:patchouli alcohol
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Accession:CHEBI:7940 term browser browse the term
Definition:A carbotricyclic compound and sesquiterpenoid tertiary alcohol that is tricyclo[5.3.1.0(3,8)]undecan-3-ol which is substituted at positions 2, 2, 6 and 8 by methyl groups (the 1R,3R,6S,7S,8S-diastereoisomer).
Synonyms:exact_synonym: (1R,4S,4aS,6R,8aS)-4,8a,9,9-tetramethyloctahydro-1,6-methanonaphthalen-1(2H)-ol
 related_synonym: (-)-(1R,3R,6S,7S,8S)-2,2,6,8-tetramethyltricyclo[5.3.1.0(3,8)]undecan-3-ol;   Formula=C15H26O;   InChI=1S/C15H26O/c1-10-5-8-15(16)13(2,3)11-6-7-14(15,4)12(10)9-11/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m0/s1;   InChIKey=GGHMUJBZYLPWFD-CUZKYEQNSA-N;   SMILES=[H][C@@]12CC[C@@]3(C)[C@@]([H])(C1)[C@@H](C)CC[C@@]3(O)C2(C)C;   [1R-(1alpha,4beta,4aalpha,6beta,8aalpha)]-octahydro-4,8a,9,9-tetramethyl-1,6-methano-1(2H)-naphthol;   patchoulanol;   patchouli camphor;   patchoulic alcohol;   patchoulol
 xref: CAS:5986-55-0;   KEGG:C09705;   KNApSAcK:C00003168
 xref_mesh: MESH:C052983
 xref: MetaCyc:CPD-11399;   PMID:20148554;   PMID:3038029;   Reaxys:5730219


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patchouli alcohol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP patchouli alcohol inhibits the reaction [Ethanol results in decreased activity of CAT protein] CTD PMID:25168850 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP patchouli alcohol inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:25168850 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]
patchouli alcohol inhibits the reaction [Ethanol results in increased expression of IL6 protein]		 CTD PMID:23348408 PMID:25168850 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK1 protein modified form] CTD PMID:23348408 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK3 protein modified form] CTD PMID:23348408 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]		 CTD PMID:23348408 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]		 CTD PMID:23348408 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP patchouli alcohol inhibits the reaction [Indomethacin results in decreased expression of PTGS1 mRNA] CTD PMID:25168850 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP patchouli alcohol inhibits the reaction [Indomethacin results in decreased expression of PTGS2 mRNA] CTD PMID:25168850 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO patchouli alcohol inhibits the reaction [TNF protein affects the localization of RELA protein]
patchouli alcohol inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]		 CTD PMID:23348408 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 patchouli alcohol inhibits the reaction [TNF protein affects the localization of RELA protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of NOS2 protein]
patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK1 protein modified form]; patchouli alcohol inhibits the reaction [TNF protein results in increased expression of MAPK3 protein modified form]
patchouli alcohol inhibits the reaction [Ethanol results in increased expression of TNF protein]		 CTD PMID:23348408 PMID:25168850 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      atom 19885
        nonmetal atom 19809
          carbon atom 19760
            organic molecular entity 19760
              isoprenoid 14074
                terpenoid 13774
                  sesquiterpenoid 3293
                    patchouli alcohol 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            organic hydride 18698
                              organic fundamental parent 18698
                                hydrocarbon 18446
                                  terpene 14074
                                    sesquiterpene 3294
                                      sesquiterpenoid 3293
                                        patchouli alcohol 11
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