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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tafamidis meglumine
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Accession:CHEBI:79345 term browser browse the term
Definition:An organoammonium salt obtained by combining tafamidis with one molar equivalent of 1-deoxy-1-(methylamino)-D-glucitol. Used for the amelioration of transthyretin-related hereditary amyloidosis.
Synonyms:exact_synonym: 1-deoxy-1-(methylazaniumyl)-D-glucitol 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylate;   2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid--1-deoxy-1-(methylamino)-D-glucitol (1/1)
 related_synonym: Formula=C21H24Cl2N2O8;   Fx-1006a;   Fx1006A;   InChI=1S/C14H7Cl2NO3.C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-6H,(H,18,19);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1;   InChIKey=DQJDBUPLRMRBAB-WZTVWXICSA-N;   SMILES=CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1;   Vyndaqel
 xref: CAS:951395-08-7;   KEGG:D09674;   PMID:22094129;   PMID:22378262;   PMID:22645360;   PMID:22645721;   PMID:23483184;   PMID:23776379;   PMID:24000164;   PMID:24101373;   PMID:25022953;   Patent:WO2013038351;   Reaxys:23441785;   Wikipedia:Tafamidis


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  CHEBI ontology 401
    role 401
      application 355
        pharmaceutical 351
          drug 351
            central nervous system drug 77
              tafamidis meglumine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 401
    subatomic particle 401
      composite particle 401
        hadron 401
          baryon 401
            nucleon 401
              atomic nucleus 401
                atom 401
                  main group element atom 394
                    main group molecular entity 394
                      s-block molecular entity 338
                        hydrogen molecular entity 337
                          hydrides 277
                            inorganic hydride 241
                              pnictogen hydride 240
                                nitrogen hydride 240
                                  ammonium 5
                                    ammonium ion derivative 5
                                      ammonium compound 0
                                        organoammonium salt 0
                                          tafamidis meglumine 0
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