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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:SB-202190
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Accession:CHEBI:79090 term browser browse the term
Definition:A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) alpha and beta.
Synonyms:exact_synonym: 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
 related_synonym: 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole;   Formula=C20H14FN3O;   InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24);   InChIKey=QHKYPYXTTXKZST-UHFFFAOYSA-N;   SB202190;   SMILES=Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
 xref: CAS:152121-30-7;   PMID:11040446;   PMID:16183336;   PMID:18995898;   PMID:21853067;   PMID:22253611;   PMID:22986232;   PMID:24455679;   PMID:9632706;   PMID:9738669;   Reaxys:10467168

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  CHEBI ontology 0
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      biological role 0
        biochemical role 0
          apoptosis inducer 0
            SB-202190 0
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  CHEBI ontology 0
    subatomic particle 0
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                          organic molecular entity 0
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                                organic heterocyclic compound 0
                                  heteroarene 0
                                    monocyclic heteroarene 0
                                      azole 0
                                        diazole 0
                                          imidazoles 0
                                            SB-202190 0
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