Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:EC 3.4.24.35 (gelatinase B) inhibitor
go back to main search page
Accession:CHEBI:79088 term browser browse the term
Definition:An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase B (EC 3.4.24.35).
Synonyms:related_synonym: 92-kDa gelatinase inhibitor;   92-kDa gelatinase inhibitors;   92-kDa type IV collagenase inhibitor;   92-kDa type IV collagenase inhibitors;   95 kDa type IV collagenase/gelatinase inhibitor;   95 kDa type IV collagenase/gelatinase inhibitors;   EC 3.4.24.35 inhibitor;   EC 3.4.24.35 inhibitors;   MMP 9 inhibitor;   MMP 9 inhibitors;   collagenase IV inhibitor;   collagenase IV inhibitors;   collagenase type IV inhibitor;   collagenase type IV inhibitors;   gelatinase B (EC 3.4.24.35) inhibitors;   gelatinase B inhibitor;   gelatinase B inhibitors;   gelatinase MMP 9 inhibitor;   gelatinase MMP 9 inhibitors;   macrophage gelatinase inhibitor;   macrophage gelatinase inhibitors;   matrix metalloproteinase 9 inhibitor;   matrix metalloproteinase 9 inhibitors;   type IV collagen metalloproteinase inhibitor;   type IV collagen metalloproteinase inhibitors;   type V collagenase inhibitor;   type V collagenase inhibitors
 xref: Wikipedia:Gelatinase_B


show annotations for term's descendants           Sort by:
prinomastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp13 matrix metallopeptidase 13 decreases activity ISO prinomastat results in decreased activity of MMP13 protein CTD PMID:17267227 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO prinomastat results in decreased activity of MMP2 protein CTD PMID:17267227 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases activity ISO prinomastat results in decreased activity of MMP3 protein CTD PMID:17267227 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp8 matrix metallopeptidase 8 decreases activity ISO prinomastat results in decreased activity of MMP8 protein CTD PMID:17267227 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO prinomastat inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        inhibitor 18875
          enzyme inhibitor 18702
            EC 3.* (hydrolase) inhibitor 18308
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 4422
                EC 3.4.24.* (metalloendopeptidase) inhibitor 849
                  EC 3.4.24.35 (gelatinase B) inhibitor 5
                    MMP-9-IN-1 0
                    MMP9 inhibitor I 0
                    isoginkgetin 0
                    prinomastat 5
                    prinomastat hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        inhibitor 18875
          enzyme inhibitor 18702
            EC 3.* (hydrolase) inhibitor 18308
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 4422
                protease inhibitor 2249
                  EC 3.4.24.* (metalloendopeptidase) inhibitor 849
                    EC 3.4.24.35 (gelatinase B) inhibitor 5
                      MMP-9-IN-1 0
                      MMP9 inhibitor I 0
                      isoginkgetin 0
                      prinomastat 5
                      prinomastat hydrochloride 0
paths to the root