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ONTOLOGY REPORT - ANNOTATIONS


Term:crocin-1
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Accession:CHEBI:79068 term browser browse the term
Definition:A diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol.
Synonyms:exact_synonym: bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate
 related_synonym: C.I. 75100;   Formula=C44H64O24;   InChI=1S/C44H64O24/c1-19(11-7-13-21(3)39(59)67-43-37(57)33(53)29(49)25(65-43)17-61-41-35(55)31(51)27(47)23(15-45)63-41)9-5-6-10-20(2)12-8-14-22(4)40(60)68-44-38(58)34(54)30(50)26(66-44)18-62-42-36(56)32(52)28(48)24(16-46)64-42/h5-14,23-38,41-58H,15-18H2,1-4H3/b6-5+,11-7+,12-8+,19-9+,20-10+,21-13+,22-14+/t23-,24-,25-,26-,27-,28-,29-,30-,31+,32+,33+,34+,35-,36-,37-,38-,41-,42-,43+,44+/m1/s1;   InChIKey=SEBIKDIMAPSUBY-RTJKDTQDSA-N;   Natural red 1;   Natural yellow 19;   Natural yellow 6;   SMILES=C\\C(\\C=C\\C=C(/C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)=C/C=C/C=C(\\C)/C=C/C=C(\\C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O;   Saffron;   alpha-crocin;   bis(beta-D-gentiobiosyl) crocetin;   crocetin di-beta-D-gentiobiose ester;   crocetin di-gentiobiose ester;   crocetin digentiobioside;   crocine;   trans-crocetin bis(beta-D-gentiobiosyl) ester
 alt_id: CHEBI:3919
 xref: CAS:39465-00-4;   CAS:42553-65-1;   HMDB:HMDB0002398;   KEGG:C08589;   KNApSAcK:C00003769
 xref_mesh: MESH:C029036
 xref: MetaCyc:CPD-8666;   PMID:14514073;   PMID:17704979;   PMID:21398065;   PMID:24132704;   PMID:24275090;   PMID:24401376;   PMID:24659065;   PMID:24697694;   PMID:24839356;   Reaxys:78445;   Wikipedia:Crocin


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crocin-1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACP5 acid phosphatase 5, tartrate resistant JBrowse link 19 11,574,660 11,578,983 RGD:6480464
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 40,230,317 40,285,531 RGD:6480464
G BAMBI BMP and activin membrane bound inhibitor JBrowse link 10 28,677,521 28,682,932 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CKM creatine kinase, M-type JBrowse link 19 45,306,413 45,322,875 RGD:6480464
G COL2A1 collagen type II alpha 1 chain JBrowse link 12 47,972,967 48,006,212 RGD:6480464
G CREB1 cAMP responsive element binding protein 1 JBrowse link 2 207,529,943 207,605,988 RGD:6480464
G CYCS cytochrome c, somatic JBrowse link 7 25,118,656 25,125,260 RGD:6480464
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 10 133,527,363 133,539,123 RGD:6480464
G GLO1 glyoxalase I JBrowse link 6 38,675,925 38,703,145 RGD:6480464
G GPT glutamic--pyruvic transaminase JBrowse link 8 144,503,068 144,507,172 RGD:6480464
G HSPA1L heat shock protein family A (Hsp70) member 1 like JBrowse link 6 31,809,619 31,815,283 RGD:6480464
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G LDLR low density lipoprotein receptor JBrowse link 19 11,089,432 11,133,820 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MIR122 microRNA 122 JBrowse link 18 58,451,074 58,451,158 RGD:6480464
G MIR29B1 microRNA 29b-1 JBrowse link 7 130,877,459 130,877,539 RGD:6480464
G MPO myeloperoxidase JBrowse link 17 58,269,855 58,280,935 RGD:6480464
G MYCN MYCN proto-oncogene, bHLH transcription factor JBrowse link 2 15,940,550 15,947,004 RGD:6480464
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 3 38,138,661 38,143,022 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G OSTM1 osteoclastogenesis associated transmembrane protein 1 JBrowse link 6 108,041,409 108,074,741 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G SMAD2 SMAD family member 2 JBrowse link 18 47,808,957 47,931,188 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TGFBR1 transforming growth factor beta receptor 1 JBrowse link 9 99,104,038 99,154,192 RGD:6480464
G TLR4 toll like receptor 4 JBrowse link 9 117,704,403 117,724,735 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TNFSF11 TNF superfamily member 11 JBrowse link 13 42,562,736 42,608,013 RGD:6480464
G TNNT2 troponin T2, cardiac type JBrowse link 1 201,359,014 201,377,828 RGD:6480464
G TRAF6 TNF receptor associated factor 6 JBrowse link 11 36,483,769 36,510,313 RGD:6480464
G VGF VGF nerve growth factor inducible JBrowse link 7 101,162,509 101,169,956 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24141
    role 24034
      chemical role 22418
        antioxidant 14842
          crocin-1 40
Path 2
Term Annotations click to browse term
  CHEBI ontology 24141
    subatomic particle 24095
      composite particle 24095
        hadron 24095
          baryon 24095
            nucleon 24095
              atomic nucleus 24095
                atom 24095
                  main group element atom 23924
                    p-block element atom 23924
                      carbon group element atom 23656
                        carbon atom 23612
                          organic molecular entity 23612
                            organic group 22086
                              organic divalent group 22060
                                organodiyl group 22060
                                  carbonyl group 22035
                                    carbonyl compound 22035
                                      carboxylic acid 21059
                                        monocarboxylic acid 19839
                                          fatty acid 18143
                                            unsaturated fatty acid 930
                                              polyunsaturated fatty acid 677
                                                carotenoic acid 49
                                                  crocetin 49
                                                    beta-D-gentiobiosyl crocetin 40
                                                      crocin-1 40
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.