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Accession:CHEBI:79042 term browser browse the term
Definition:A member of the class of 1-benzofurans that is propionamide in which one of the amide hydrogens is replaced by a [(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl group. A melatonin receptor agonist used for the treatment of non-24-hour sleep-wake disorder.
Synonyms:exact_synonym: N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide
 related_synonym: BMS 214778;   Formula=C15H19NO2;   Hetlioz;   InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1;   InChIKey=PTOIAAWZLUQTIO-GXFFZTMASA-N;   SMILES=CCC(=O)NC[C@@H]1C[C@H]1c1cccc2OCCc12;   VEC 162;   tasimelteonum
 xref: CAS:609799-22-6 "ChemIDplus";   CAS:609799-22-6 "KEGG DRUG";   Drug_Central:4820 "DrugCentral";   KEGG:D09388;   PMID:12661062 "Europe PMC";   PMID:19054552 "Europe PMC";   PMID:19579175 "Europe PMC";   PMID:21548834 "Europe PMC";   PMID:22680635 "Europe PMC";   PMID:22916799 "Europe PMC";   PMID:24228714 "Europe PMC";   PMID:24534583 "Europe PMC";   PMID:24610704 "Europe PMC";   PMID:24757362 "Europe PMC";   PMID:24759294 "Europe PMC";   PMID:24892896 "Europe PMC";   PMID:24958945 "Europe PMC";   Patent:WO2007137224;   Patent:WO2007137244;   Patent:WO2013173707;   Reaxys:15439325 "Reaxys";   Wikipedia:Tasimelteon

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Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        pharmacological role 18680
          agonist 18011
            melatonin receptor agonist 0
              tasimelteon 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        carboacyl group 16941
                                          univalent carboacyl group 16941
                                            carbamoyl group 16621
                                              carboxamide 16621
                                                monocarboxylic acid amide 13181
                                                  fatty amide 752
                                                    primary fatty amide 10
                                                      propionamide 1
                                                        tasimelteon 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.