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Accession:CHEBI:78887 term browser browse the term
Definition:A member of the class of benzotriazines that is 1,2,4-benzotriazine carrying an amino substituent at position 3 and two oxido substituents at positions 1 and 4.
Synonyms:exact_synonym: 1,2,4-benzotriazin-3-amine 1,4-dioxide
 related_synonym: 3-Amino-1,2,4-benzotriazine 1,4-dioxide;   Formula=C7H6N4O2;   InChI=1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4H,(H2,8,9);   InChIKey=ORYDPOVDJJZGHQ-UHFFFAOYSA-N;   SMILES=Nc1n[n+]([O-])c2ccccc2[n+]1[O-];   SR 4233
 xref: Beilstein:179322 "ChemIDplus";   CAS:27314-97-2 "ChemIDplus";   CAS:27314-97-2 "KEGG DRUG";   KEGG:D06167
 xref_mesh: MESH:C049947
 xref: PMID:22331808 "Europe PMC";   PMID:22531857 "Europe PMC";   PMID:22666522 "Europe PMC";   PMID:22946564 "Europe PMC";   PMID:23033890 "Europe PMC";   PMID:23888874 "Europe PMC";   PMID:24362462 "Europe PMC";   PMID:24395863 "Europe PMC";   PMID:24529061 "Europe PMC";   PMID:7954337 "Europe PMC";   Reaxys:179322 "Reaxys";   Wikipedia:Tirapazamine

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tirapazamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        antimicrobial agent 17151
          antibacterial agent 12904
            tirapazamine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  organic heteropolycyclic compound 17423
                                    organic heterobicyclic compound 15889
                                      mancude organic heterobicyclic parent 5093
                                        benzotriazine 13
                                          1,2,4-benzotriazine 7
                                            tirapazamine 6
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.