CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 4-terpineol
Accession: CHEBI:78884
browse the term
Definition: A terpineol that is 1-menthene carrying a hydroxy substituent at position 4.
Synonyms: exact_synonym: 4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol
related_synonym: 1-Menthene-4-ol; 1-Methyl-4-isopropyl-1-cyclohexen-4-ol; 1-Terpinen-4-ol; 1-isopropyl-4-methylcyclohex-3-en-1-ol; 1-p-Menthen-4-ol; 1-para-Menthen-4-ol; 4-Carvomenthenol; 4-Methyl-1-(1-methylethyl)-3-cyclohexen-1-ol; 4-Methyl-1-isopropyl-3-cyclohexen-1-ol; Formula=C10H18O; InChI=1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3; InChIKey=WRYLYDPHFGVWKC-UHFFFAOYSA-N; SMILES=CC(C)C1(O)CCC(C)=CC1; Terpene-4-ol; Terpin-4-en-1-ol; Terpinen-4-ol; Terpinene-4-ol; Terpinenol-4; alpha-terpinen-4-ol; p-Menth-1-en-4-ol
alt_id: CHEBI:132655
xref: BPDB:2012; CAS:562-74-3; HMDB:HMDB0035833; KEGG:C17073
xref_mesh: MESH:C034019
xref: PMID:21760828; PMID:22998411; PMID:23292030; PMID:23469686; PMID:23649340; PMID:24349880; PMID:24460330; PMID:24731375; Pubchem:11230; Reaxys:1906603
G
Ctsd
cathepsin D
increases expression multiple interactions
ISO
terpinenol-4 results in increased expression of CTSD mRNA Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of CTSD mRNA]
CTD
PMID:31393563
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
G
Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
multiple interactions
ISO
terpinenol-4 inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]
CTD
PMID:31393563
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
G
Esr1
estrogen receptor 1
multiple interactions increases activity
ISO
NCOA2 protein promotes the reaction [terpinenol-4 results in increased activity of ESR1 protein]
CTD
PMID:31393563
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
G
Greb1
growth regulating estrogen receptor binding 1
multiple interactions increases expression
ISO
Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of GREB1 mRNA]
CTD
PMID:31393563
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
G
Ncoa2
nuclear receptor coactivator 2
multiple interactions
ISO
NCOA2 protein promotes the reaction [terpinenol-4 results in increased activity of ESR1 protein]
CTD
PMID:31393563
NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451
G
Pgr
progesterone receptor
multiple interactions increases expression
ISO
Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of PGR mRNA]
CTD
PMID:31393563
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
G
Sec14l2
SEC14-like lipid binding 2
multiple interactions
ISO
terpinenol-4 inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]
CTD
PMID:31393563
NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788
G
Ugt2b15
UDP glucuronosyltransferase family 2 member B15
increases metabolic processing
EXP
UGT2B15 protein results in increased metabolism of terpinenol-4
CTD
PMID:7574722
NCBI chr14:21,122,866...21,138,450
Ensembl chr14:20,768,015...20,783,589
G
Ugt2b34l1
UDP glucuronosyltransferase 2 family, polypeptide B34 like 1
multiple interactions
ISO
terpinenol-4 inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]
CTD
PMID:31393563
NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
G
Ar
androgen receptor
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased activity of AR protein]
CTD
PMID:31393563
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925
G
Ctsd
cathepsin D
increases expression multiple interactions
ISO
Tea Tree Oil results in increased expression of CTSD mRNA Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA]
CTD
PMID:31393563
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
G
Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA]
CTD
PMID:31393563
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
G
Esr1
estrogen receptor 1
increases activity
ISO
Tea Tree Oil results in increased activity of ESR1 protein
CTD
PMID:31393563
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
G
Greb1
growth regulating estrogen receptor binding 1
increases expression multiple interactions
ISO
Tea Tree Oil results in increased expression of GREB1 mRNA Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA]
CTD
PMID:31393563
NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
G
Pgr
progesterone receptor
increases expression multiple interactions
ISO
Tea Tree Oil results in increased expression of PGR mRNA Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]
CTD
PMID:31393563
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
G
Sec14l2
SEC14-like lipid binding 2
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA]
CTD
PMID:31393563
NCBI chr14:83,197,384...83,222,059
Ensembl chr14:78,973,808...78,993,788
G
Ugt2b34l1
UDP glucuronosyltransferase 2 family, polypeptide B34 like 1
multiple interactions
ISO
Tea Tree Oil inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA]
CTD
PMID:31393563
NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all