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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:9-[2-(phosphonomethoxy)ethyl]guanine
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Accession:CHEBI:7880 term browser browse the term
Definition:A phosphoethanolamine that has formula C8H12N5O5P.
Synonyms:related_synonym: 9-((2-Phosphonylmethoxy)ethyl)guanine;   Formula=C8H12N5O5P;   InChI=1S/C8H12N5O5P/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-18-4-19(15,16)17/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14);   InChIKey=NZVORGQIEFTOQZ-UHFFFAOYSA-N;   PMEG;   SMILES=Nc1nc(=O)c2ncn(CCOCP(O)(O)=O)c2[nH]1
 xref: CAS:114088-58-3;   KEGG:C11184
 xref_mesh: MESH:C063380


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9-[2-(phosphonomethoxy)ethyl]guanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases response to substance		 ISO 9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine]; Quercetin inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine analog]
SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine; SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine analog		 CTD PMID:23856525 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20083
    role 20034
      biological role 20033
        biochemical role 19660
          metabolite 19642
            eukaryotic metabolite 19345
              algal metabolite 14180
                guanine 4015
                  9-[2-(phosphonomethoxy)ethyl]guanine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20083
    subatomic particle 20081
      composite particle 20081
        hadron 20081
          baryon 20081
            nucleon 20081
              atomic nucleus 20081
                atom 20081
                  main group element atom 19982
                    p-block element atom 19982
                      carbon group element atom 19909
                        carbon atom 19902
                          organic molecular entity 19902
                            organic molecule 19849
                              organic cyclic compound 19604
                                organic heterocyclic compound 18824
                                  organic heteropolycyclic compound 18293
                                    organic heterobicyclic compound 17178
                                      imidazopyrimidine 5638
                                        purines 5636
                                          aminopurine 4461
                                            2-aminopurines 4051
                                              guanine 4015
                                                9-[2-(phosphonomethoxy)ethyl]guanine 1
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