|
G |
ALAD |
aminolevulinate dehydratase |
multiple interactions decreases activity |
ISO |
Ditiocarb inhibits the reaction [Ditiocarb analog results in decreased activity of ALAD protein]; Ditiocarb inhibits the reaction [lead acetate results in decreased activity of ALAD protein] |
CTD |
PMID:2177232 |
|
NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
|
|
G |
ALDH3A1 |
aldehyde dehydrogenase 3 family member A1 |
increases chemical synthesis |
EXP |
ALDH3A1 protein results in increased chemical synthesis of Ditiocarb |
CTD |
PMID:18591790 |
|
NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943
|
|
G |
ANXA1 |
annexin A1 |
increases expression |
ISO |
Ditiocarb results in increased expression of ANXA1 mRNA |
CTD |
PMID:16603213 |
|
NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
|
|
G |
APAF1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
EXP |
[[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] |
CTD |
PMID:22951949 |
|
NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
|
|
G |
APP |
amyloid beta precursor protein |
multiple interactions |
EXP |
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP protein] |
CTD |
PMID:28242320 |
|
NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
|
|
G |
BACE1 |
beta-secretase 1 |
multiple interactions |
EXP |
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA] |
CTD |
PMID:28242320 |
|
NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
|
|
G |
CASP1 |
caspase 1 |
multiple interactions affects expression |
ISO |
[Ditiocarb co-treated with Zinc] results in decreased expression of CASP1 protein Ditiocarb affects the expression of CASP1 protein |
CTD |
PMID:25929180 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
|
|
G |
CASP3 |
caspase 3 |
multiple interactions |
ISO EXP |
[Ditiocarb co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] |
CTD |
PMID:22951949 PMID:27592447 |
|
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
|
|
G |
CASP8 |
caspase 8 |
multiple interactions |
EXP |
[Ditiocarb binds to Copper] which results in increased activity of CASP8 protein |
CTD |
PMID:22951949 |
|
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
|
|
G |
CASP9 |
caspase 9 |
multiple interactions |
EXP |
[[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] |
CTD |
PMID:22951949 |
|
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
|
|
G |
CAT |
catalase |
decreases expression |
EXP |
Ditiocarb results in decreased expression of CAT mRNA |
CTD |
PMID:8279580 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
|
|
G |
CCS |
copper chaperone for superoxide dismutase |
decreases expression |
ISO |
Ditiocarb results in decreased expression of CCS protein |
CTD |
PMID:20452388 |
|
NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
|
|
G |
CNP |
2',3'-cyclic nucleotide 3' phosphodiesterase |
increases expression |
ISO |
Ditiocarb results in increased expression of CNP protein |
CTD |
PMID:22874009 |
|
NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740
|
|
G |
CP |
ceruloplasmin |
multiple interactions |
EXP |
Ditiocarb inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] |
CTD |
PMID:16756764 |
|
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
|
|
G |
CYCS |
cytochrome c, somatic |
multiple interactions |
EXP |
[[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein]; [Ditiocarb binds to Copper] which affects the localization of CYCS protein |
CTD |
PMID:22951949 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
|
|
G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
multiple interactions |
ISO EXP |
Ditiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] |
CTD |
PMID:18493746 |
|
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
|
|
G |
CYP2A6 |
cytochrome P450 family 2 subfamily A member 6 |
decreases activity |
EXP |
Ditiocarb results in decreased activity of CYP2A6 protein |
CTD |
PMID:8819299 |
|
NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
|
|
G |
CYP2C19 |
cytochrome P450 family 2 subfamily C member 19 |
decreases activity |
EXP |
Ditiocarb results in decreased activity of CYP2C19 protein |
CTD |
PMID:8819299 |
|
NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
|
|
G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
decreases activity multiple interactions |
ISO EXP |
Ditiocarb results in decreased activity of CYP2E1 protein Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]; Ditiocarb inhibits the reaction [pyridine results in increased activity of CYP2E1 protein] [Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene; [Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of Lamotrigine]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]] |
CTD |
PMID:1356728 PMID:1538706 PMID:1664256 PMID:8558417 PMID:8560479 PMID:8819299 PMID:9010585 PMID:9618253 PMID:10215755 PMID:12086689 PMID:12746132 PMID:15306208 PMID:19961160 More...
|
|
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
|
|
G |
DDIT4 |
DNA damage inducible transcript 4 |
increases expression |
ISO |
Ditiocarb results in increased expression of DDIT4 protein |
CTD |
PMID:24764117 |
|
NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
|
|
G |
DPYSL2 |
dihydropyrimidinase like 2 |
increases expression |
ISO |
Ditiocarb results in increased expression of DPYSL2 protein |
CTD |
PMID:22874009 |
|
NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
|
|
G |
GSTM1 |
glutathione S-transferase mu 1 |
multiple interactions |
ISO |
Ditiocarb binds to and results in decreased activity of GSTM1 protein |
CTD |
PMID:6095330 |
|
NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
|
|
G |
GSTP1 |
glutathione S-transferase pi 1 |
increases expression |
ISO |
Ditiocarb results in increased expression of GSTP1 protein |
CTD |
PMID:22874009 |
|
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
|
|
G |
HADHA |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
decreases expression |
ISO |
Ditiocarb results in decreased expression of HADHA protein |
CTD |
PMID:22874009 |
|
NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
|
|
G |
HBG2 |
hemoglobin subunit gamma 2 |
multiple interactions increases expression |
EXP |
Ditiocarb promotes the reaction [Primaquine results in increased expression of HBG2 protein] Ditiocarb results in increased expression of HBG2 protein |
CTD |
PMID:19616568 |
|
NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605
|
|
G |
HMOX1 |
heme oxygenase 1 |
increases expression |
ISO |
Ditiocarb results in increased expression of HMOX1 protein |
CTD |
PMID:19467251 PMID:20452388 PMID:22874009 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
|
|
G |
HSD11B2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity |
EXP |
Ditiocarb results in decreased activity of HSD11B2 protein |
CTD |
PMID:22796344 |
|
NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
|
|
G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions |
EXP |
[[Paraquat co-treated with Ditiocarb] results in decreased activity of SOD1 protein] which results in increased expression of ICAM1 protein |
CTD |
PMID:10644010 |
|
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
|
|
G |
IFNG |
interferon gamma |
multiple interactions increases expression |
ISO EXP |
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased metabolism of Nitric Oxide]; Polysaccharides inhibits the reaction [Ditiocarb results in increased expression of IFNG protein] Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP protein]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN1 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN2 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of Nitric Oxide] |
CTD |
PMID:11498278 PMID:26826268 PMID:28242320 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
|
|
G |
IL1B |
interleukin 1 beta |
increases expression multiple interactions |
ISO |
Ditiocarb results in increased expression of IL1B protein Polysaccharides inhibits the reaction [Ditiocarb results in increased expression of IL1B protein] |
CTD |
PMID:26826268 |
|
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
|
|
G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein]; Nitric Oxide affects the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:16603213 |
|
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
|
|
G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Ditiocarb results in increased phosphorylation of MAPK3 protein Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]; Nitric Oxide affects the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:16603213 |
|
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
|
|
G |
MBP |
myelin basic protein |
increases expression |
ISO |
Ditiocarb results in increased expression of MBP protein |
CTD |
PMID:22874009 |
|
NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683
|
|
G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
Ditiocarb inhibits the reaction [Isoflurane affects the localization of NFKB1 protein] |
CTD |
PMID:18708911 |
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
|
|
G |
NLRP3 |
NLR family pyrin domain containing 3 |
affects expression multiple interactions |
ISO |
Ditiocarb affects the expression of NLRP3 protein [Ditiocarb co-treated with Zinc] results in decreased expression of NLRP3 protein |
CTD |
PMID:25929180 |
|
NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
|
|
G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions |
ISO EXP |
Ditiocarb inhibits the reaction [Isoflurane results in increased expression of NOS2 protein] Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA] |
CTD |
PMID:18708911 PMID:28242320 |
|
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
|
|
G |
PLA2G4A |
phospholipase A2 group IVA |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; Nitric Oxide affects the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; Nitric Oxide affects the reaction [Ditiocarb results in increased expression of PLA2G4A protein]; U 0126 inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; U 0126 inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A protein] Ditiocarb results in increased expression of PLA2G4A mRNA; Ditiocarb results in increased expression of PLA2G4A protein |
CTD |
PMID:16603213 |
|
NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
|
|
G |
PLN |
phospholamban |
multiple interactions increases phosphorylation |
ISO |
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ditiocarb results in increased phosphorylation of PLN protein] |
CTD |
PMID:16288776 |
|
NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
|
|
G |
PRDX2 |
peroxiredoxin 2 |
increases expression |
ISO |
Ditiocarb results in increased expression of PRDX2 protein |
CTD |
PMID:22874009 |
|
NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
|
|
G |
PRDX6 |
peroxiredoxin 6 |
increases expression |
ISO |
Ditiocarb results in increased expression of PRDX6 protein |
CTD |
PMID:22874009 |
|
NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
|
|
G |
PRNP |
prion protein (Kanno blood group) |
increases expression |
ISO |
Ditiocarb results in increased expression of PRNP protein |
CTD |
PMID:20452388 |
|
NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
|
|
G |
PSEN1 |
presenilin 1 |
multiple interactions |
EXP |
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN1 mRNA] |
CTD |
PMID:28242320 |
|
NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691
|
|
G |
PSEN2 |
presenilin 2 |
multiple interactions |
EXP |
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN2 mRNA] |
CTD |
PMID:28242320 |
|
NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726
|
|
G |
PYGB |
glycogen phosphorylase B |
increases expression |
ISO |
Ditiocarb results in increased expression of PYGB protein |
CTD |
PMID:22874009 |
|
NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012
|
|
G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
Ditiocarb inhibits the reaction [Isoflurane affects the localization of RELA protein] |
CTD |
PMID:18708911 |
|
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
|
|
G |
SLC6A3 |
solute carrier family 6 member 3 |
increases expression |
ISO |
Ditiocarb results in increased expression of SLC6A3 protein |
CTD |
PMID:22874009 |
|
NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
|
|
G |
SNCA |
synuclein alpha |
increases expression |
ISO |
Ditiocarb results in increased expression of SNCA protein |
CTD |
PMID:22874009 |
|
NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
|
|
G |
SOD1 |
superoxide dismutase 1 |
decreases activity increases expression multiple interactions |
EXP ISO |
Ditiocarb results in decreased activity of SOD1 protein; Ditiocarb results in decreased activity of SOD1 protein mutant form Ditiocarb results in increased expression of SOD1 mRNA Ditiocarb inhibits the reaction [lactacystin affects the localization of SOD1 protein mutant form] [[Paraquat co-treated with Ditiocarb] results in decreased activity of SOD1 protein] which results in increased expression of ICAM1 protein Ditiocarb results in increased expression of SOD1 protein |
CTD |
PMID:8279580 PMID:10644010 PMID:15034941 PMID:16681429 PMID:19467251 PMID:20452388 PMID:22874009 More...
|
|
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
|
|
G |
TH |
tyrosine hydroxylase |
multiple interactions |
ISO |
Ditiocarb results in decreased expression of and results in increased phosphorylation of TH protein |
CTD |
PMID:22874009 |
|
NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
|
|
G |
TNF |
tumor necrosis factor |
multiple interactions |
ISO |
Ditiocarb inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein] |
CTD |
PMID:10486238 |
|
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
|
|
G |
TP53 |
tumor protein p53 |
multiple interactions increases expression |
EXP |
Ditiocarb inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]; Ditiocarb inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein] Ditiocarb results in increased expression of TP53 protein |
CTD |
PMID:10951577 PMID:11964141 |
|
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
|
|
G |
UBA1 |
ubiquitin like modifier activating enzyme 1 |
multiple interactions |
EXP ISO |
Ditiocarb results in decreased activity of and results in decreased ubiquitination of UBA1 protein Ditiocarb binds to and results in decreased activity of UBA1 protein |
CTD |
PMID:22874009 PMID:25714994 |
|
NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
|
|
G |
UCP2 |
uncoupling protein 2 |
increases expression |
ISO |
Ditiocarb results in increased expression of UCP2 protein |
CTD |
PMID:18082129 |
|
NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843
|
|
|
G |
HSD3B1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases activity |
EXP |
ferbam results in decreased activity of HSD3B1 protein |
CTD |
PMID:36965607 |
|
NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
|
|
G |
MT1G |
metallothionein 1G |
increases expression |
EXP |
ferbam results in increased expression of MT1G mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
|
|
G |
TGFB1 |
transforming growth factor beta 1 |
decreases activity |
EXP |
ferbam results in decreased activity of TGFB1 protein |
CTD |
PMID:31652400 |
|
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
|
|
|
G |
ALS2 |
alsin Rho guanine nucleotide exchange factor ALS2 |
multiple interactions |
ISO |
methyldithiocarbamate affects the reaction [Lipopolysaccharides results in increased expression of ALS2 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 2:201,700,267...201,780,933
Ensembl chr 2:201,700,267...201,782,112
|
|
G |
CAT |
catalase |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CAT mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
|
|
G |
CCL11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL11 protein] |
CTD |
PMID:24056979 |
|
NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
|
|
G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL2 protein] |
CTD |
PMID:24056979 |
|
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
|
|
G |
CCL3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] |
CTD |
PMID:19339665 PMID:24056979 |
|
NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
|
|
G |
CCL4 |
C-C motif chemokine ligand 4 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein] |
CTD |
PMID:24056979 |
|
NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
|
|
G |
CCL5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL5 protein] |
CTD |
PMID:24056979 |
|
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
|
|
G |
CD40 |
CD40 molecule |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
|
|
G |
CD55 |
CD55 molecule (Cromer blood group) |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CD55 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
|
|
G |
CFB |
complement factor B |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CFB mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
|
|
G |
CLEC2D |
C-type lectin domain family 2 member D |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CLEC2D mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr12:9,669,713...9,699,553
Ensembl chr12:9,664,969...9,699,553
|
|
G |
CLEC7A |
C-type lectin domain containing 7A |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC7A mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
|
|
G |
CRTAM |
cytotoxic and regulatory T cell molecule |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CRTAM mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643
|
|
G |
CSF2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] |
CTD |
PMID:19339665 PMID:24056979 |
|
NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
|
|
G |
CTSB |
cathepsin B |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CTSB mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
|
|
G |
CXCL9 |
C-X-C motif chemokine ligand 9 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL9 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CXCL9 protein] |
CTD |
PMID:16321413 PMID:24056979 |
|
NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
|
|
G |
DHX58 |
DExH-box helicase 58 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of DHX58 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714
|
|
G |
EIF2AK2 |
eukaryotic translation initiation factor 2 alpha kinase 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of EIF2AK2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522
|
|
G |
EREG |
epiregulin |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of EREG mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749
|
|
G |
FCGR1A |
Fc gamma receptor Ia |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of FCGR1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675
|
|
G |
GAB1 |
GRB2 associated binding protein 1 |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GAB1 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 4:143,336,876...143,474,565
Ensembl chr 4:143,336,876...143,474,565
|
|
G |
GCLM |
glutamate-cysteine ligase modifier subunit |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GCLM mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
|
|
G |
GPX3 |
glutathione peroxidase 3 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of GPX3 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
|
|
G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
|
|
G |
IDH1 |
isocitrate dehydrogenase (NADP(+)) 1 |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IDH1 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
|
|
G |
IFI16 |
interferon gamma inducible protein 16 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI204 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155
|
|
G |
IFIH1 |
interferon induced with helicase C domain 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIH1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
|
|
G |
IFIT1B |
interferon induced protein with tetratricopeptide repeats 1B |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr10:89,378,056...89,385,205
Ensembl chr10:89,378,056...89,385,205
|
|
G |
IFIT2 |
interferon induced protein with tetratricopeptide repeats 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
|
|
G |
IFIT3 |
interferon induced protein with tetratricopeptide repeats 3 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473
|
|
G |
IFNA8 |
interferon alpha 8 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNA2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 9:21,409,117...21,410,185
Ensembl chr 9:21,409,117...21,410,185
|
|
G |
IFNB1 |
interferon beta 1 |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
|
|
G |
IFNG |
interferon gamma |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] |
CTD |
PMID:15933225 PMID:19339665 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
|
|
G |
IL10 |
interleukin 10 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased expression of IL10 mRNA; [Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased secretion of IL10 protein; [methyldithiocarbamate binds to Copper] promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; [Nadolol co-treated with Mifepristone] promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; Buthionine Sulfoximine promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] |
CTD |
PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979 |
|
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
|
|
G |
IL12A |
interleukin 12A |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] |
CTD |
PMID:15933225 |
|
NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
|
|
G |
IL12B |
interleukin 12B |
multiple interactions |
ISO |
[Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979 |
|
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
|
|
G |
IL18 |
interleukin 18 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] |
CTD |
PMID:15933225 |
|
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
|
|
G |
IL1A |
interleukin 1 alpha |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] |
CTD |
PMID:15933225 |
|
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
|
|
G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:15933225 PMID:19339665 PMID:24056979 |
|
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
|
|
G |
IL6 |
interleukin 6 |
multiple interactions |
ISO |
Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:19339665 |
|
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
|
|
G |
IRF3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF3 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
|
|
G |
IRF4 |
interferon regulatory factor 4 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF4 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
|
|
G |
IRF5 |
interferon regulatory factor 5 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF5 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
|
|
G |
IRF7 |
interferon regulatory factor 7 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF7 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
|
|
G |
IRGM |
immunity related GTPase M |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRGM1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736
|
|
G |
ISG15 |
ISG15 ubiquitin like modifier |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of ISG15 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
|
|
G |
KLRK1 |
killer cell lectin like receptor K1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of KLRK1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874
|
|
G |
MALT1 |
MALT1 paracaspase |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MALT1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477
|
|
G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:15933225 |
|
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
|
|
G |
MAPK14 |
mitogen-activated protein kinase 14 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:15933225 |
|
NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
|
|
G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:15933225 |
|
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
|
|
G |
MAPK8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:15933225 |
|
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
|
|
G |
MASP1 |
MBL associated serine protease 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MASP1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
|
|
G |
MBL2 |
mannose binding lectin 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MBL2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
|
|
G |
MIF |
macrophage migration inhibitory factor |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MIF mRNA] |
CTD |
PMID:15933225 |
|
NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
|
|
G |
MTF1 |
metal regulatory transcription factor 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MTF1 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592
|
|
G |
MX1 |
MX dynamin like GTPase 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071
|
|
G |
MX2 |
MX dynamin like GTPase 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393
|
|
G |
MYD88 |
MYD88 innate immune signal transduction adaptor |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
|
|
G |
MYO1F |
myosin IF |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MYO1F mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr19:8,520,778...8,577,442
Ensembl chr19:8,520,778...8,577,442
|
|
G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
|
|
G |
NOD1 |
nucleotide binding oligomerization domain containing 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NOD1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784
|
|
G |
PPP1R15B |
protein phosphatase 1 regulatory subunit 15B |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PPP1R15B mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 1:204,395,826...204,411,817
Ensembl chr 1:204,396,492...204,411,887
|
|
G |
PRDX1 |
peroxiredoxin 1 |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PRDX1 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
|
|
G |
PRNP |
prion protein (Kanno blood group) |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PRNP mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
|
|
G |
PSMB5 |
proteasome 20S subunit beta 5 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB5 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230
|
|
G |
RIGI |
RNA sensor RIG-I |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIGI mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
|
|
G |
RIPK2 |
receptor interacting serine/threonine kinase 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
|
|
G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
|
|
G |
SRXN1 |
sulfiredoxin 1 |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of SRXN1 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
|
|
G |
STAT1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
|
|
G |
STAT5A |
signal transducer and activator of transcription 5A |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT5A mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
|
|
G |
TIRAP |
TIR domain containing adaptor protein |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TIRAP mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845
|
|
G |
TLR3 |
toll like receptor 3 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TLR3 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073
|
|
G |
TNF |
tumor necrosis factor |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:19339665 |
|
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
|
|
G |
TOR1AIP2 |
torsin 1A interacting protein 2 |
multiple interactions |
ISO |
methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of TOR1AIP2 mRNA] |
CTD |
PMID:24056979 |
|
NCBI chr 1:179,839,976...179,877,803
Ensembl chr 1:179,839,967...179,877,803
|
|
G |
TXNRD2 |
thioredoxin reductase 2 |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of TXNRD2 mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820
|
|
G |
UBA1 |
ubiquitin like modifier activating enzyme 1 |
multiple interactions |
EXP |
methyldithiocarbamate results in increased activity of and results in increased ubiquitination of UBA1 protein |
CTD |
PMID:25714994 |
|
NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
|
|
G |
XPA |
XPA, DNA damage recognition and repair factor |
multiple interactions |
ISO |
methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of XPA mRNA] |
CTD |
PMID:19339665 |
|
NCBI chr 9:97,654,398...97,697,340
Ensembl chr 9:97,674,909...97,697,340
|
|
|
G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1] |
CTD |
PMID:10636889 |
|
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
|
|
G |
ACTA2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] |
CTD |
PMID:15078482 |
|
NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
|
|
G |
ACTB |
actin beta |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
|
|
G |
AGT |
angiotensinogen |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] |
CTD |
PMID:10712386 |
|
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
|
|
G |
AIF1 |
allograft inflammatory factor 1 |
multiple interactions decreases expression |
ISO |
pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the expression of AIF1 protein] pyrrolidine dithiocarbamic acid results in decreased expression of AIF1 protein |
CTD |
PMID:36682417 |
|
NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
|
|
G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:24431215 |
|
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
|
|
G |
ALB |
albumin |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased abundance of Hydrogen Peroxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA] |
CTD |
PMID:11961005 |
|
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
|
|
G |
ALDH2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ALDH2 mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
|
|
G |
ALPL |
alkaline phosphatase, biomineralization associated |
multiple interactions |
EXP |
cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein] |
CTD |
PMID:34575692 |
|
NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
|
|
G |
APP |
amyloid beta precursor protein |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in decreased susceptibility to [APP protein modified form binds to APP protein modified form] |
CTD |
PMID:17409235 |
|
NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
|
|
G |
AR |
androgen receptor |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR protein] |
CTD |
PMID:16139439 |
|
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
|
|
G |
ARHGDIA |
Rho GDP dissociation inhibitor alpha |
decreases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of ARHGDIA mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA |
CTD |
PMID:15477007 |
|
NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,721...81,871,378
|
|
G |
ARPC2 |
actin related protein 2/3 complex subunit 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:218,217,189...218,254,348
Ensembl chr 2:218,217,141...218,254,356
|
|
G |
ATF4 |
activating transcription factor 4 |
multiple interactions |
EXP ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] |
CTD |
PMID:15477007 PMID:20920558 |
|
NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
|
|
G |
ATP7A |
ATPase copper transporting alpha |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of ATP7A |
CTD |
PMID:25070243 |
|
NCBI chr X:77,910,693...78,050,395
Ensembl chr X:77,910,690...78,050,395
|
|
G |
BAK1 |
BCL2 antagonist/killer 1 |
multiple interactions |
ISO |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein] |
CTD |
PMID:22085843 |
|
NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
|
|
G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein] |
CTD |
PMID:22085843 |
|
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
|
|
G |
BCL2 |
BCL2 apoptosis regulator |
increases phosphorylation multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid results in increased phosphorylation of BCL2 protein [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BCL2 mRNA] |
CTD |
PMID:12482581 PMID:16139439 PMID:20920558 PMID:21161674 PMID:22085843 |
|
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
|
|
G |
BCL2A1 |
BCL2 related protein A1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
|
|
G |
BCL2L1 |
BCL2 like 1 |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BCL2L1 protein] [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein] |
CTD |
PMID:18789402 PMID:22085843 |
|
NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
|
|
G |
BDNF |
brain derived neurotrophic factor |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein] |
CTD |
PMID:22261313 |
|
NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
|
|
G |
BGLAP |
bone gamma-carboxyglutamate protein |
multiple interactions |
EXP |
cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] |
CTD |
PMID:34575692 |
|
NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
|
|
G |
BIRC3 |
baculoviral IAP repeat containing 3 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] |
CTD |
PMID:14527959 |
|
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
|
|
G |
BIRC5 |
baculoviral IAP repeat containing 5 |
multiple interactions decreases expression |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 protein] pyrrolidine dithiocarbamic acid results in decreased expression of BIRC5 protein |
CTD |
PMID:16139439 PMID:21161674 PMID:29541389 |
|
NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
|
|
G |
CASP1 |
caspase 1 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form] pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased cleavage of CASP1 protein] |
CTD |
PMID:31586597 PMID:35190838 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
|
|
G |
CASP3 |
caspase 3 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein] [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein] [pyrrolidine dithiocarbamic acid binds to Copper] which results in increased activity of CASP3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased activity of CASP3 protein] |
CTD |
PMID:10941151 PMID:18671963 PMID:20920558 PMID:21687928 PMID:22085843 PMID:28070109 PMID:30086653 More...
|
|
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
|
|
G |
CASP7 |
caspase 7 |
multiple interactions |
ISO |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein] |
CTD |
PMID:20920558 PMID:22085843 |
|
NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
|
|
G |
CASP8 |
caspase 8 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
|
|
G |
CASP9 |
caspase 9 |
multiple interactions increases activity |
ISO EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein] pyrrolidine dithiocarbamic acid results in increased activity of CASP9 protein |
CTD |
PMID:12198114 PMID:20920558 PMID:22085843 |
|
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
|
|
G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] |
CTD |
PMID:11006087 PMID:11961005 PMID:12016129 PMID:12472797 PMID:16129981 PMID:16600694 PMID:18500357 PMID:22225513 More...
|
|
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
|
|
G |
CCL20 |
C-C motif chemokine ligand 20 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL20 mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
|
|
G |
CCL23 |
C-C motif chemokine ligand 23 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL9 mRNA] |
CTD |
PMID:22225513 |
|
NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972
|
|
G |
CCL3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
|
|
G |
CCL3L1 |
C-C motif chemokine ligand 3 like 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3L1 mRNA] |
CTD |
PMID:15477007 |
|
Ensembl chr17:36,194,869...36,196,758
|
|
G |
CCL4 |
C-C motif chemokine ligand 4 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 protein] |
CTD |
PMID:16129981 |
|
NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
|
|
G |
CCL5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] |
CTD |
PMID:10495789 PMID:22225513 |
|
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
|
|
G |
CCND1 |
cyclin D1 |
decreases expression multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of CCND1 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of CCND1 mRNA] |
CTD |
PMID:14603533 PMID:31048002 |
|
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
|
|
G |
CCNE1 |
cyclin E1 |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of CCNE1 protein |
CTD |
PMID:14603533 |
|
NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
|
|
G |
CCNG1 |
cyclin G1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151
|
|
G |
CCT5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
|
|
G |
CD14 |
CD14 molecule |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in decreased expression of CD14 mRNA] |
CTD |
PMID:20368581 PMID:36539177 |
|
NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
|
|
G |
CD200 |
CD200 molecule |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 3:112,332,573...112,362,812
Ensembl chr 3:112,332,347...112,362,812
|
|
G |
CD44 |
CD44 molecule (IN blood group) |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
|
|
G |
CDH1 |
cadherin 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of CDH1 protein] |
CTD |
PMID:36722465 |
|
NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
|
|
G |
CDH17 |
cadherin 17 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
|
|
G |
CDH2 |
cadherin 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CDH2 protein] |
CTD |
PMID:36722465 |
|
NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
|
|
G |
CDK2 |
cyclin dependent kinase 2 |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of CDK2 protein |
CTD |
PMID:14603533 |
|
NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
|
|
G |
CDK4 |
cyclin dependent kinase 4 |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of CDK4 protein |
CTD |
PMID:14603533 |
|
NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
|
|
G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in decreased expression of CDKN1A mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein] |
CTD |
PMID:14603533 PMID:15048878 PMID:31048002 |
|
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
|
|
G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1B protein] |
CTD |
PMID:15048878 |
|
NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
|
|
G |
CEBPB |
CCAAT enhancer binding protein beta |
increases response to substance multiple interactions |
EXP |
CEBPB results in increased susceptibility to pyrrolidine dithiocarbamic acid pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter] |
CTD |
PMID:9359698 |
|
NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
|
|
G |
CHUK |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] |
CTD |
PMID:11739238 |
|
NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
|
|
G |
CLEC10A |
C-type lectin domain containing 10A |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC10A mRNA] |
CTD |
PMID:17342418 |
|
NCBI chr17:7,074,537...7,080,251
Ensembl chr17:7,074,537...7,080,307
|
|
G |
CLN3 |
CLN3 lysosomal/endosomal transmembrane protein, battenin |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
|
|
G |
CNR1 |
cannabinoid receptor 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Gemcitabine results in increased expression of CNR1 mRNA] |
CTD |
PMID:21525939 |
|
NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
|
|
G |
CNR2 |
cannabinoid receptor 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Gemcitabine results in increased expression of CNR2 mRNA] |
CTD |
PMID:21525939 |
|
NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
|
|
G |
CNTNAP1 |
contactin associated protein 1 |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of CNTNAP1 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr17:42,682,531...42,699,993
Ensembl chr17:42,682,531...42,699,993
|
|
G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA] cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA] |
CTD |
PMID:15078482 PMID:34575692 |
|
NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
|
|
G |
COL1A2 |
collagen type I alpha 2 chain |
multiple interactions |
EXP |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]] |
CTD |
PMID:34152691 |
|
NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
|
|
G |
COL6A1 |
collagen type VI alpha 1 chain |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr21:45,981,770...46,005,048
Ensembl chr21:45,981,770...46,005,050
|
|
G |
COMT |
catechol-O-methyltransferase |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
|
|
G |
CP |
ceruloplasmin |
multiple interactions increases secretion increases expression |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein] pyrrolidine dithiocarbamic acid results in increased secretion of CP protein pyrrolidine dithiocarbamic acid results in increased expression of CP mRNA; pyrrolidine dithiocarbamic acid results in increased expression of CP protein |
CTD |
PMID:17032174 |
|
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
|
|
G |
CPSF1 |
cleavage and polyadenylation specific factor 1 |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA pyrrolidine dithiocarbamic acid results in increased expression of CPSF1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 8:144,393,231...144,409,335
Ensembl chr 8:144,393,229...144,409,335
|
|
G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
|
|
G |
CREM |
cAMP responsive element modulator |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
|
|
G |
CTBP1 |
C-terminal binding protein 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 4:1,211,445...1,250,355
Ensembl chr 4:1,211,445...1,250,333
|
|
G |
CUL5 |
cullin 5 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:108,008,898...108,107,761
Ensembl chr11:108,008,898...108,107,761
|
|
G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL1 mRNA] |
CTD |
PMID:16129981 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
|
|
G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of CXCL10 mRNA] |
CTD |
PMID:36539177 |
|
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
|
|
G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein] |
CTD |
PMID:16129981 PMID:21507677 |
|
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
|
|
G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions |
EXP ISO |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]]; pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzene results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzo(a)pyrene results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [chromium hexavalent ion results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [PLA2G1B protein results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Vehicle Emissions results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]] pyrrolidine dithiocarbamic acid inhibits the reaction [CPG-oligonucleotide results in increased expression of CXCL8] |
CTD |
PMID:11306435 PMID:12016129 PMID:15528384 PMID:19626664 PMID:21779360 PMID:22595112 PMID:23535185 PMID:23748240 PMID:34152691 More...
|
|
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
|
|
G |
CYCS |
cytochrome c, somatic |
multiple interactions |
EXP ISO |
[pyrrolidine dithiocarbamic acid binds to Copper] which affects the localization of CYCS protein [Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein] |
CTD |
PMID:18671963 PMID:20920558 PMID:22085843 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
|
|
G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
CTD |
PMID:9756946 PMID:18078826 |
|
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
|
|
G |
CYP2A13 |
cytochrome P450 family 2 subfamily A member 13 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP2A13 mRNA] |
CTD |
PMID:23884085 |
|
NCBI chr19:41,088,451...41,096,195
Ensembl chr19:41,088,451...41,096,195
|
|
G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [aflatoxin G1 results in increased expression of CYP2E1 protein] |
CTD |
PMID:36997055 |
|
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
|
|
G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Fenretinide results in increased expression of DDIT3 protein] pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA] |
CTD |
PMID:16972258 PMID:20920558 |
|
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
|
|
G |
DNAJB1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of DNAJB1 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391
|
|
G |
DUSP4 |
dual specificity phosphatase 4 |
multiple interactions |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684
|
|
G |
EGF |
epidermal growth factor |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] |
CTD |
PMID:16340751 |
|
NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
|
|
G |
EGFR |
epidermal growth factor receptor |
multiple interactions |
EXP ISO |
[Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein pyrrolidine dithiocarbamic acid affects the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of EGFR protein] |
CTD |
PMID:18346929 PMID:38003411 |
|
NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
|
|
G |
EGR1 |
early growth response 1 |
multiple interactions increases expression |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA]; SB 203580 promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA] |
CTD |
PMID:12482581 |
|
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
|
|
G |
EGR2 |
early growth response 2 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
|
|
G |
EGR3 |
early growth response 3 |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA pyrrolidine dithiocarbamic acid results in increased expression of EGR3 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
|
|
G |
ERBB4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [pervanadate results in increased cleavage of ERBB4 protein] |
CTD |
PMID:9685416 |
|
NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
|
|
G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] |
CTD |
PMID:17141290 |
|
NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
|
|
G |
FN1 |
fibronectin 1 |
multiple interactions |
EXP |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]] |
CTD |
PMID:12388107 PMID:34152691 |
|
NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
|
|
G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA] pyrrolidine dithiocarbamic acid results in increased expression of FOS mRNA pyrrolidine dithiocarbamic acid results in increased expression of FOS protein |
CTD |
PMID:7539260 PMID:15477007 PMID:17032174 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
|
|
G |
FOSL2 |
FOS like 2, AP-1 transcription factor subunit |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317
|
|
G |
FYB1 |
FYN binding protein 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 5:39,105,252...39,274,528
Ensembl chr 5:39,105,252...39,274,528
|
|
G |
G3BP2 |
G3BP stress granule assembly factor 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein] |
CTD |
PMID:28816235 |
|
NCBI chr 4:75,642,786...75,724,437
Ensembl chr 4:75,641,849...75,724,589
|
|
G |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
increases expression |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of GAPDH mRNA |
CTD |
PMID:11108245 |
|
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
|
|
G |
GATA1 |
GATA binding protein 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
CTD |
PMID:10656287 |
|
NCBI chr X:48,786,590...48,794,311
Ensembl chr X:48,786,540...48,794,311
|
|
G |
GFAP |
glial fibrillary acidic protein |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of GFAP mRNA] |
CTD |
PMID:36539177 |
|
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
|
|
G |
GFRA2 |
GDNF family receptor alpha 2 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357
|
|
G |
GNAS |
GNAS complex locus |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA |
CTD |
PMID:15477007 |
|
NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
|
|
G |
GNLY |
granulysin |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNLY mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNLY mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852
|
|
G |
GPER1 |
G protein-coupled estrogen receptor 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein] |
CTD |
PMID:22645130 |
|
NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
|
|
G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the expression of AIF1 protein]; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] |
CTD |
PMID:34082047 PMID:36682417 |
|
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
|
|
G |
GSK3B |
glycogen synthase kinase 3 beta |
increases phosphorylation |
ISO |
pyrrolidine dithiocarbamic acid results in increased phosphorylation of GSK3B protein |
CTD |
PMID:17409235 |
|
NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
|
|
G |
GTF2H2C |
GTF2H2 family member C |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 5:69,560,191...69,595,221
Ensembl chr 5:69,560,191...69,595,221 Ensembl chr 5:69,560,191...69,595,221
|
|
G |
GZMA |
granzyme A |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA] |
CTD |
PMID:12700414 |
|
NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
|
|
G |
GZMB |
granzyme B |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA] |
CTD |
PMID:12700414 |
|
NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
|
|
G |
H2AX |
H2A.X variant histone |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein]] |
CTD |
PMID:36997055 |
|
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
|
|
G |
HADHA |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
|
|
G |
HARS1 |
histidyl-tRNA synthetase 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 5:140,673,905...140,691,370
Ensembl chr 5:140,673,035...140,691,537
|
|
G |
HCK |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
|
|
G |
HLA-B |
major histocompatibility complex, class I, B |
multiple interactions |
EXP |
[HLA-B protein alternative form co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of and affects the localization of RELA protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of HLA-B protein alternative form; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of PSMB9 protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of TAP1 protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of IL1B protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of TNF protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of HLA-B protein alternative form]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of TAP1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of TNF protein] |
CTD |
PMID:36423715 |
|
NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
|
|
G |
HMBS |
hydroxymethylbilane synthase |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
CTD |
PMID:10656287 |
|
NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834
|
|
G |
HMGB1 |
high mobility group box 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
|
|
G |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMGCS2 mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
|
|
G |
HMOX1 |
heme oxygenase 1 |
multiple interactions increases stability increases expression |
EXP ISO |
pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 protein] pyrrolidine dithiocarbamic acid results in increased stability of HMOX1 mRNA pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 protein pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Lead results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of HMOX1 mRNA] |
CTD |
PMID:9837857 PMID:16972258 PMID:18078826 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
|
|
G |
HNRNPUL1 |
heterogeneous nuclear ribonucleoprotein U like 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr19:41,262,557...41,307,787
Ensembl chr19:41,262,496...41,307,787
|
|
G |
HSD11B2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity |
EXP |
pyrrolidine dithiocarbamic acid results in decreased activity of HSD11B2 protein |
CTD |
PMID:22796344 |
|
NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
|
|
G |
HSP90B1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
ISO |
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] |
CTD |
PMID:20920558 |
|
NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931
|
|
G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] |
CTD |
PMID:20920558 |
|
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
|
|
G |
HSPA8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] pyrrolidine dithiocarbamic acid results in increased expression of HSPA8 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
|
|
G |
HYAL3 |
hyaluronidase 3 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 3:50,292,832...50,299,405
Ensembl chr 3:50,292,831...50,299,405
|
|
G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions decreases expression |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of ICAM1 mRNA |
CTD |
PMID:10495789 PMID:12131776 PMID:14572618 PMID:16129981 PMID:17416599 |
|
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
|
|
G |
IFNG |
interferon gamma |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [IFNG protein results in increased abundance of Nitrites] pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein] |
CTD |
PMID:8903404 PMID:12845421 PMID:18039960 PMID:25766886 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
|
|
G |
IFNGR2 |
interferon gamma receptor 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr21:33,402,882...33,437,516
Ensembl chr21:33,403,413...33,479,348
|
|
G |
IKBKB |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of IKBKB protein] |
CTD |
PMID:26860689 |
|
NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
|
|
G |
IL10 |
interleukin 10 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased expression of IL10 mRNA] |
CTD |
PMID:11124598 |
|
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
|
|
G |
IL12B |
interleukin 12B |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15778123 |
|
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
|
|
G |
IL17A |
interleukin 17A |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA] |
CTD |
PMID:12016129 |
|
NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
|
|
G |
IL18 |
interleukin 18 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] |
CTD |
PMID:15178407 |
|
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
|
|
G |
IL1B |
interleukin 1 beta |
multiple interactions |
EXP ISO |
[pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of IL1B protein; pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased secretion of IL1B protein] pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased abundance of 8-epi-prostaglandin F2alpha]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form] pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of IL1B protein] |
CTD |
PMID:7539260 PMID:8662662 PMID:11530235 PMID:11578593 PMID:11970852 PMID:12879239 PMID:18039960 PMID:19626664 PMID:21565208 PMID:21779360 PMID:23535185 PMID:25766886 PMID:31586597 PMID:33161052 PMID:35190838 PMID:35349355 PMID:36423715 PMID:36539177 PMID:36775139 More...
|
|
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
|
|
G |
IL2 |
interleukin 2 |
multiple interactions |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA] |
CTD |
PMID:12700414 PMID:15477007 |
|
NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
|
|
G |
IL2RB |
interleukin 2 receptor subunit beta |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118
|
|
G |
IL6 |
interleukin 6 |
multiple interactions decreases secretion |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA] pyrrolidine dithiocarbamic acid results in decreased secretion of IL6 protein atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]] |
CTD |
PMID:11970852 PMID:12016129 PMID:21779360 PMID:23535185 PMID:23665308 PMID:32613688 PMID:33161052 PMID:34152691 PMID:35349355 PMID:36539177 PMID:36722465 PMID:36775139 More...
|
|
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
|
|
G |
IRF1 |
interferon regulatory factor 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 protein] |
CTD |
PMID:11739238 |
|
NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
|
|
G |
IRF4 |
interferon regulatory factor 4 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
|
|
G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein] pyrrolidine dithiocarbamic acid results in increased expression of JUN mRNA; pyrrolidine dithiocarbamic acid results in increased expression of JUN protein |
CTD |
PMID:12482581 PMID:15477007 PMID:17032174 |
|
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
|
|
G |
KL |
klotho |
multiple interactions increases expression |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL protein] pyrrolidine dithiocarbamic acid results in increased expression of KL protein |
CTD |
PMID:21389697 |
|
NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
|
|
G |
KLF4 |
KLF transcription factor 4 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
|
|
G |
KLF6 |
KLF transcription factor 6 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
|
|
G |
KLK3 |
kallikrein related peptidase 3 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of KLK3 mRNA] |
CTD |
PMID:16139439 |
|
NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764
|
|
G |
LCMT2 |
leucine carboxyl methyltransferase 2 |
increases expression multiple interactions increases response to substance |
EXP ISO |
pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 protein LCMT2 results in increased susceptibility to [pyrrolidine dithiocarbamic acid co-treated with Fluorouracil] LCMT2 results in increased susceptibility to pyrrolidine dithiocarbamic acid pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter] |
CTD |
PMID:9359698 |
|
NCBI chr15:43,323,649...43,330,573
Ensembl chr15:43,323,649...43,330,582
|
|
G |
LCN2 |
lipocalin 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of LCN2 mRNA] |
CTD |
PMID:36539177 |
|
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
|
|
G |
LCP1 |
lymphocyte cytosolic protein 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871
|
|
G |
LIF |
LIF interleukin 6 family cytokine |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of LIF mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
|
|
G |
LTBP4 |
latent transforming growth factor beta binding protein 4 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr19:40,593,166...40,629,820
Ensembl chr19:40,592,883...40,629,818
|
|
G |
MADCAM1 |
mucosal vascular addressin cell adhesion molecule 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] |
CTD |
PMID:12388057 |
|
NCBI chr19:496,486...505,343
Ensembl chr19:489,176...505,343
|
|
G |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
|
|
G |
MAP2K4 |
mitogen-activated protein kinase kinase 4 |
multiple interactions |
ISO |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:22085843 |
|
NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
|
|
G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions decreases activity |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein] pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; Glutathione inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the susceptibility to [Copper co-treated with pyrrolidine dithiocarbamic acid] |
CTD |
PMID:10658192 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 |
|
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
|
|
G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein] |
CTD |
PMID:10941151 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 |
|
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
|
|
G |
MAPK8 |
mitogen-activated protein kinase 8 |
multiple interactions increases activity |
ISO |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein |
CTD |
PMID:10658192 PMID:10941151 PMID:20920558 PMID:22085843 |
|
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
|
|
G |
MAPK9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:15557793 PMID:22085843 |
|
NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
|
|
G |
MAPT |
microtubule associated protein tau |
decreases phosphorylation |
ISO |
pyrrolidine dithiocarbamic acid results in decreased phosphorylation of MAPT protein |
CTD |
PMID:17409235 |
|
NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
|
|
G |
MIR146A |
microRNA 146a |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA] |
CTD |
PMID:22099153 |
|
NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
|
|
G |
MLXIP |
MLX interacting protein |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of MLXIP protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of MLXIP protein] |
CTD |
PMID:33930463 |
|
NCBI chr12:122,078,756...122,147,344
Ensembl chr12:122,078,756...122,147,344
|
|
G |
MMP1 |
matrix metallopeptidase 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]] |
CTD |
PMID:32613688 |
|
NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
|
|
G |
MMP13 |
matrix metallopeptidase 13 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [CPG-oligonucleotide results in increased secretion of MMP13 protein] |
CTD |
PMID:23331101 |
|
NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
|
|
G |
MMP2 |
matrix metallopeptidase 2 |
decreases expression multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of MMP2 mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of MMP2 mRNA] |
CTD |
PMID:19272247 PMID:23566884 |
|
NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
|
|
G |
MMP9 |
matrix metallopeptidase 9 |
decreases activity multiple interactions decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased activity of MMP9 protein pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of MMP9 mRNA |
CTD |
PMID:16340751 PMID:22033475 PMID:23566884 |
|
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
|
|
G |
MPO |
myeloperoxidase |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased activity of MPO protein] |
CTD |
PMID:12879239 |
|
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
|
|
G |
MST1R |
macrophage stimulating 1 receptor |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of MST1R mRNA |
CTD |
PMID:18593918 |
|
NCBI chr 3:49,887,002...49,903,873
Ensembl chr 3:49,887,002...49,903,873
|
|
G |
MT1B |
metallothionein 1B |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of MT1B mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1B mRNA |
CTD |
PMID:15477007 |
|
NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204
|
|
G |
MT1E |
metallothionein 1E |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of MT1E mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1E mRNA |
CTD |
PMID:15477007 |
|
NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
|
|
G |
MT1F |
metallothionein 1F |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1F mRNA pyrrolidine dithiocarbamic acid results in increased expression of MT1F mRNA |
CTD |
PMID:15477007 |
|
NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
|
|
G |
MT1G |
metallothionein 1G |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of MT1G mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1G mRNA |
CTD |
PMID:15477007 |
|
NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
|
|
G |
MT1H |
metallothionein 1H |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1H mRNA |
CTD |
PMID:15477007 |
|
NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
|
|
G |
MT1X |
metallothionein 1X |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of MT1X mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1X mRNA |
CTD |
PMID:15477007 |
|
NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
|
|
G |
MTA1 |
metastasis associated 1 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MTA1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr14:105,419,827...105,470,729
Ensembl chr14:105,419,820...105,470,729
|
|
G |
MUC5AC |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions |
EXP |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]] |
CTD |
PMID:34152691 |
|
NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
|
|
G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of MYC mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of MYC |
CTD |
PMID:15477007 PMID:21161674 PMID:25070243 |
|
NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
|
|
G |
MYH1 |
myosin heavy chain 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MYH1 protein] |
CTD |
PMID:24431215 |
|
NCBI chr17:10,492,307...10,518,542
Ensembl chr17:10,492,307...10,518,542
|
|
G |
MYH7 |
myosin heavy chain 7 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein] |
CTD |
PMID:28816235 |
|
NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
|
|
G |
NAA80 |
N-alpha-acetyltransferase 80, NatH catalytic subunit |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 3:50,296,402...50,299,405
Ensembl chr 3:50,296,402...50,299,416
|
|
G |
NELL1 |
neural EGFL like 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686
|
|
G |
NFE2 |
nuclear factor, erythroid 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
CTD |
PMID:10656287 |
|
NCBI chr12:54,292,111...54,301,015
Ensembl chr12:54,292,111...54,301,015
|
|
G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of NFE2L2 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of NFE2L2 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
|
|
G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein] |
CTD |
PMID:10416616 PMID:11006087 PMID:11286985 PMID:11578593 PMID:11739238 PMID:11961005 PMID:11970852 PMID:12016129 PMID:14527959 PMID:15178407 More...
|
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
|
|
G |
NFKB2 |
nuclear factor kappa B subunit 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] |
CTD |
PMID:25559736 |
|
NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524
|
|
G |
NFKBIA |
NFKB inhibitor alpha |
multiple interactions decreases expression |
EXP ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] pyrrolidine dithiocarbamic acid results in decreased expression of NFKBIA mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of NFKBIA protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NFKBIA protein] |
CTD |
PMID:9434740 PMID:10636889 PMID:10921504 PMID:11006087 PMID:11739238 PMID:11923223 PMID:12879239 PMID:17342418 PMID:26860689 More...
|
|
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
|
|
G |
NGF |
nerve growth factor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein] |
CTD |
PMID:17651887 |
|
NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
|
|
G |
NGFR |
nerve growth factor receptor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein] |
CTD |
PMID:17651887 |
|
NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
|
|
G |
NKG7 |
natural killer cell granule protein 7 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr19:51,371,620...51,372,654
Ensembl chr19:51,371,606...51,372,701
|
|
G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased expression of NLRP3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [swietenine inhibits the reaction [Glucose results in increased expression of NLRP3 protein]] |
CTD |
PMID:35190838 PMID:36066211 |
|
NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
|
|
G |
NMI |
N-myc and STAT interactor |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894
|
|
G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of NOS2 mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [[Ozone results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ozone results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased expression of NOS2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [resveratrol results in decreased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [resveratrol results in decreased expression of NOS2 protein] |
CTD |
PMID:7539260 PMID:8662662 PMID:8903404 PMID:9788894 PMID:11530235 PMID:11923223 PMID:12879239 PMID:16925772 PMID:17342418 PMID:17416599 PMID:18039960 PMID:20621070 PMID:21565208 PMID:22227475 PMID:23542513 PMID:23735732 PMID:24239652 PMID:24365262 PMID:24859013 PMID:25766886 PMID:28138957 PMID:29248572 More...
|
|
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
|
|
G |
NOTCH3 |
notch receptor 3 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
|
|
G |
NPPA |
natriuretic peptide A |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA protein] |
CTD |
PMID:28816235 |
|
NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
|
|
G |
NPPB |
natriuretic peptide B |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB protein] |
CTD |
PMID:28816235 |
|
NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
|
|
G |
NR4A3 |
nuclear receptor subfamily 4 group A member 3 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891
|
|
G |
ODC1 |
ornithine decarboxylase 1 |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ODC1 mRNA pyrrolidine dithiocarbamic acid results in increased expression of ODC1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
|
|
G |
PAX8 |
paired box 8 |
multiple interactions decreases expression decreases chemical synthesis |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] pyrrolidine dithiocarbamic acid results in decreased chemical synthesis of PAX8 protein |
CTD |
PMID:11108245 |
|
NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
|
|
G |
PCNA |
proliferating cell nuclear antigen |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of PCNA mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of PCNA protein] |
CTD |
PMID:31048002 PMID:38003411 |
|
NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
|
|
G |
PLA2G1B |
phospholipase A2 group IB |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [PLA2G1B protein results in increased expression of CXCL8 protein] |
CTD |
PMID:15528384 |
|
NCBI chr12:120,322,115...120,327,779
Ensembl chr12:120,322,115...120,327,779
|
|
G |
PLAU |
plasminogen activator, urokinase |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] |
CTD |
PMID:16340751 |
|
NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
|
|
G |
PNPLA4 |
patatin like phospholipase domain containing 4 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr X:7,898,247...7,927,724
Ensembl chr X:7,898,247...7,927,739
|
|
G |
POU2F2 |
POU class 2 homeobox 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr19:42,086,110...42,197,936
Ensembl chr19:42,086,110...42,196,585
|
|
G |
PPP1CA |
protein phosphatase 1 catalytic subunit alpha |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of PPP1CA mRNA |
CTD |
PMID:15477007 |
|
NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183
|
|
G |
PPP1R10 |
protein phosphatase 1 regulatory subunit 10 |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of PPP1R10 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of PPP1R10 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 6:30,600,413...30,617,243
Ensembl chr 6:30,600,413...30,618,612
|
|
G |
PRF1 |
perforin 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA] |
CTD |
PMID:12700414 |
|
NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
|
|
G |
PSMB8 |
proteasome 20S subunit beta 8 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB8 protein] |
CTD |
PMID:36423715 |
|
NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
|
|
G |
PSMB9 |
proteasome 20S subunit beta 9 |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of PSMB9 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB9 protein] |
CTD |
PMID:36423715 |
|
NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
|
|
G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Homocysteine results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [sodium arsenite results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:8662662 PMID:11530235 PMID:11835400 PMID:16765938 PMID:17767925 PMID:21565208 PMID:21779360 PMID:24239652 PMID:24365262 PMID:24859013 PMID:25888188 PMID:29248572 PMID:36775139 PMID:38003411 More...
|
|
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
|
|
G |
RAC1 |
Rac family small GTPase 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA] |
CTD |
PMID:12719791 |
|
NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
|
|
G |
RBBP4 |
RB binding protein 4, chromatin remodeling factor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in decreased expression of RBBP4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in decreased expression of RBBP4 protein] |
CTD |
PMID:37866543 |
|
NCBI chr 1:32,651,208...32,686,211
Ensembl chr 1:32,651,142...32,686,211
|
|
G |
REL |
REL proto-oncogene, NF-kB subunit |
multiple interactions |
EXP ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of REL protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of REL protein] |
CTD |
PMID:11970852 PMID:15477007 PMID:26860689 |
|
NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612
|
|
G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity |
EXP ISO |
[HLA-B protein alternative form co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of and affects the localization of RELA protein; pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Resveratrol affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid promotes the reaction [andrographolide results in decreased expression of and results in decreased localization of RELA protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [swietenine inhibits the reaction [Glucose results in increased expression of RELA protein]]; Resveratrol promotes the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of RELA] pyrrolidine dithiocarbamic acid inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein] pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein] pyrrolidine dithiocarbamic acid results in decreased activity of RELA protein |
CTD |
PMID:10416616 PMID:11739238 PMID:11961005 PMID:11970852 PMID:12016129 PMID:12388107 PMID:14527959 PMID:15178407 PMID:15382119 PMID:16925772 PMID:17767925 PMID:18039960 PMID:20621070 PMID:21161674 PMID:24431215 PMID:24436987 PMID:25559736 PMID:26860689 PMID:30086653 PMID:31586597 PMID:32613688 PMID:33930463 PMID:35190838 PMID:35917943 PMID:36066211 PMID:36423715 PMID:36539177 PMID:37866543 PMID:38003411 More...
|
|
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
|
|
G |
RELB |
RELB proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] |
CTD |
PMID:11970852 |
|
NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192
|
|
G |
RHOG |
ras homolog family member G |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:3,826,978...3,840,959
Ensembl chr11:3,826,978...3,840,959
|
|
G |
RNASET2 |
ribonuclease T2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 6:166,922,113...166,956,550
Ensembl chr 6:166,922,113...166,957,191
|
|
G |
RUNX2 |
RUNX family transcription factor 2 |
multiple interactions |
EXP |
cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] |
CTD |
PMID:34575692 |
|
NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
|
|
G |
SART1 |
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:65,961,734...65,980,137
Ensembl chr11:65,961,728...65,980,137
|
|
G |
SERPINE1 |
serpin family E member 1 |
multiple interactions increases expression |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA] pyrrolidine dithiocarbamic acid results in increased expression of SERPINE1 mRNA |
CTD |
PMID:12719791 |
|
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
|
|
G |
SF3B4 |
splicing factor 3b subunit 4 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803
|
|
G |
SFTPC |
surfactant protein C |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of SFTPC protein] |
CTD |
PMID:28070109 |
|
NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479
|
|
G |
SLA |
Src like adaptor |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 8:133,036,728...133,102,602
Ensembl chr 8:133,036,728...133,102,912
|
|
G |
SLC1A2 |
solute carrier family 1 member 2 |
increases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of SLC1A2 protein pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 protein] |
CTD |
PMID:17409235 PMID:22645130 PMID:24782323 |
|
NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
|
|
G |
SLC1A3 |
solute carrier family 1 member 3 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 protein] |
CTD |
PMID:24782323 |
|
NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
|
|
G |
SLC3A2 |
solute carrier family 3 member 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
|
|
G |
SNRNP70 |
small nuclear ribonucleoprotein U1 subunit 70 |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SNRNP70 mRNA pyrrolidine dithiocarbamic acid results in increased expression of SNRNP70 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr19:49,085,451...49,108,604
Ensembl chr19:49,085,419...49,108,605
|
|
G |
SOD1 |
superoxide dismutase 1 |
multiple interactions decreases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SOD1 mRNA pyrrolidine dithiocarbamic acid results in decreased expression of SOD1 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
|
|
G |
SOD2 |
superoxide dismutase 2 |
multiple interactions increases expression |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA] pyrrolidine dithiocarbamic acid results in increased expression of SOD2 mRNA |
CTD |
PMID:9434740 PMID:10653605 PMID:12031898 PMID:22261313 |
|
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
|
|
G |
SP7 |
Sp7 transcription factor |
multiple interactions |
EXP |
cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA] |
CTD |
PMID:34575692 |
|
NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315
|
|
G |
SPP1 |
secreted phosphoprotein 1 |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of SPP1 |
CTD |
PMID:21076490 |
|
NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
|
|
G |
SRGN |
serglycin |
multiple interactions increases expression |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SRGN mRNA pyrrolidine dithiocarbamic acid results in increased expression of SRGN mRNA |
CTD |
PMID:15477007 |
|
NCBI chr10:69,087,603...69,104,811
Ensembl chr10:69,088,103...69,104,805
|
|
G |
SRI |
sorcin |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose results in decreased expression of SRI protein] |
CTD |
PMID:33930463 |
|
NCBI chr 7:88,205,115...88,226,976
Ensembl chr 7:88,205,115...88,226,993
|
|
G |
SRPRA |
SRP receptor subunit alpha |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr11:126,235,930...126,268,895
Ensembl chr11:126,262,938...126,269,144
|
|
G |
STAT3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
|
|
G |
SYP |
synaptophysin |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of SYP mRNA] |
CTD |
PMID:21161674 |
|
NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218
|
|
G |
TAP1 |
transporter 1, ATP binding cassette subfamily B member |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of TAP1 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of TAP1 protein] |
CTD |
PMID:36423715 |
|
NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
|
|
G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid affects the reaction [Doxorubicin results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of and results in increased secretion of TGFB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TGFB1 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TGFB1 protein] |
CTD |
PMID:11124598 PMID:12472797 PMID:19272247 PMID:19639047 PMID:26860689 PMID:36722465 More...
|
|
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
|
|
G |
TH |
tyrosine hydroxylase |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] |
CTD |
PMID:34082047 |
|
NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
|
|
G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA] |
CTD |
PMID:12472797 PMID:19272247 |
|
NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
|
|
G |
TIMP2 |
TIMP metallopeptidase inhibitor 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] |
CTD |
PMID:15078482 |
|
NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
|
|
G |
TINF2 |
TERF1 interacting nuclear factor 2 |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of TINF2 mRNA |
CTD |
PMID:21731707 |
|
NCBI chr14:24,239,640...24,242,674
Ensembl chr14:24,238,286...24,242,663
|
|
G |
TNF |
tumor necrosis factor |
multiple interactions decreases secretion increases stability decreases expression |
EXP ISO |
[pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of TNF protein; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Nitric Oxide]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein] pyrrolidine dithiocarbamic acid results in decreased secretion of TNF protein pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein] pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein] pyrrolidine dithiocarbamic acid results in increased stability of TNF mRNA pyrrolidine dithiocarbamic acid results in decreased expression of TNF mRNA |
CTD |
PMID:8903404 PMID:9756946 PMID:10416616 PMID:10495789 PMID:10653605 PMID:10878378 PMID:10921504 PMID:11006087 PMID:11578593 PMID:11675405 PMID:11699074 PMID:11970852 PMID:12131776 PMID:12388057 PMID:12879239 PMID:14572618 PMID:15161907 PMID:16112155 PMID:16129981 PMID:18039960 PMID:18500357 PMID:21565208 PMID:23535185 PMID:25559736 PMID:25766886 PMID:30796934 PMID:31586597 PMID:32613688 PMID:33161052 PMID:35349355 PMID:36423715 PMID:36775139 PMID:36997055 More...
|
|
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
|
|
G |
TNFRSF1B |
TNF receptor superfamily member 1B |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
|
|
G |
TP53 |
tumor protein p53 |
multiple interactions decreases expression |
EXP ISO |
[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]; pyrrolidine dithiocarbamic acid results in increased oxidation of and results in increased expression of TP53 protein pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of TP53 protein |
CTD |
PMID:11964141 PMID:16049548 PMID:25559736 |
|
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
|
|
G |
TPO |
thyroid peroxidase |
multiple interactions decreases expression decreases activity |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of TPO mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] |
CTD |
PMID:11108245 |
|
NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711
|
|
G |
TRAF1 |
TNF receptor associated factor 1 |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173
|
|
G |
TRIB2 |
tribbles pseudokinase 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734
|
|
G |
TSHB |
thyroid stimulating hormone subunit beta |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TSHB protein results in increased abundance of Hydrogen Peroxide] |
CTD |
PMID:11108245 |
|
NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
|
|
G |
TSLP |
thymic stromal lymphopoietin |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Glupearl 19S results in increased expression of TSLP mRNA] |
CTD |
PMID:32493875 |
|
NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
|
|
G |
TYROBP |
transmembrane immune signaling adaptor TYROBP |
multiple interactions |
EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295
|
|
G |
UBA1 |
ubiquitin like modifier activating enzyme 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in decreased activity of and results in decreased ubiquitination of UBA1 protein |
CTD |
PMID:25714994 |
|
NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
|
|
G |
UBE2L6 |
ubiquitin conjugating enzyme E2 L6 |
increases expression multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of UBE2L6 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBE2L6 mRNA |
CTD |
PMID:15477007 |
|
NCBI chr11:57,551,662...57,567,935
Ensembl chr11:57,551,656...57,568,284
|
|
G |
UBL4A |
ubiquitin like 4A |
multiple interactions |
EXP |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBL4A mRNA |
CTD |
PMID:15477007 |
|
NCBI chr X:154,483,717...154,486,615
Ensembl chr X:154,483,717...154,486,615
|
|
G |
VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] |
CTD |
PMID:10712386 |
|
NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
|
|
G |
VIM |
vimentin |
multiple interactions decreases expression |
EXP ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of VIM protein] pyrrolidine dithiocarbamic acid results in decreased expression of VIM protein |
CTD |
PMID:15477007 PMID:30310660 PMID:36722465 |
|
NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
|
|
|
G |
AKR1C2 |
aldo-keto reductase family 1 member C2 |
increases activity |
EXP |
Thiram results in increased activity of AKR1C2 promoter |
CTD |
PMID:21195160 |
|
NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
|
|
G |
AMPD3 |
adenosine monophosphate deaminase 3 |
increases expression |
EXP |
Thiram results in increased expression of AMPD3 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579
|
|
G |
ANXA10 |
annexin A10 |
increases expression |
EXP |
Thiram results in increased expression of ANXA10 mRNA |
CTD |
PMID:32194361 |
|
NCBI chr 4:168,092,537...168,187,736
Ensembl chr 4:168,092,537...168,187,736
|
|
G |
ARG1 |
arginase 1 |
decreases expression |
EXP |
Thiram results in decreased expression of ARG1 mRNA |
CTD |
PMID:32194361 |
|
NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
|
|
G |
ATF3 |
activating transcription factor 3 |
increases expression |
EXP |
Thiram results in increased expression of ATF3 mRNA |
CTD |
PMID:23999411 PMID:27965148 |
|
NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
|
|
G |
CASP1 |
caspase 1 |
affects expression |
ISO |
Thiram affects the expression of CASP1 protein |
CTD |
PMID:25929180 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
|
|
G |
CCR2 |
C-C motif chemokine receptor 2 |
decreases expression |
EXP |
Thiram results in decreased expression of CCR2 mRNA |
CTD |
PMID:19371601 |
|
NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
|
|
G |
CD86 |
CD86 molecule |
increases expression |
EXP |
Thiram results in increased expression of CD86 protein |
CTD |
PMID:19665512 |
|
NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
|
|
G |
CREB1 |
cAMP responsive element binding protein 1 |
increases expression |
EXP |
Thiram results in increased expression of CREB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
|
|
G |
CREM |
cAMP responsive element modulator |
increases expression |
EXP |
Thiram results in increased expression of CREM mRNA |
CTD |
PMID:19371601 |
|
NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
|
|
G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
increases expression increases secretion multiple interactions |
EXP |
Thiram results in increased expression of CXCL8 mRNA Thiram results in increased secretion of CXCL8 protein SB 203580 affects the reaction [Thiram results in increased secretion of CXCL8 protein] |
CTD |
PMID:18494145 PMID:19878716 PMID:21920952 PMID:27965148 |
|
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
|
|
G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
increases expression |
EXP |
Thiram results in increased expression of CYP1A1 mRNA; Thiram results in increased expression of CYP1A1 protein |
CTD |
PMID:32194361 |
|
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
|
|
G |
CYP2C19 |
cytochrome P450 family 2 subfamily C member 19 |
decreases expression |
EXP |
Thiram results in decreased expression of CYP2C19 protein |
CTD |
PMID:32194361 |
|
NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
|
|
G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
increases metabolic processing multiple interactions |
ISO |
CYP2E1 protein results in increased metabolism of Thiram Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] |
CTD |
PMID:12458634 |
|
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
|
|
G |
CYP7A1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression |
EXP |
Thiram results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:32194361 |
|
NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
|
|
G |
DNAJB4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
EXP |
Thiram results in increased expression of DNAJB4 mRNA |
CTD |
PMID:23999411 PMID:27965148 |
|
NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
|
|
G |
FTH1 |
ferritin heavy chain 1 |
increases expression |
EXP |
Thiram results in increased expression of FTH1 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
|
|
G |
FTL |
ferritin light chain |
increases expression |
EXP |
Thiram results in increased expression of FTL mRNA |
CTD |
PMID:24211530 |
|
NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
|
|
G |
G6PC1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
EXP |
Thiram results in decreased expression of G6PC1 mRNA |
CTD |
PMID:32194361 |
|
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
|
|
G |
GCLM |
glutamate-cysteine ligase modifier subunit |
increases expression |
EXP |
Thiram results in increased expression of GCLM mRNA |
CTD |
PMID:23999411 PMID:24211530 PMID:27965148 |
|
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
|
|
G |
HMOX1 |
heme oxygenase 1 |
increases expression |
ISO EXP |
Thiram results in increased expression of HMOX1 mRNA |
CTD |
PMID:23445166 PMID:24211530 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
|
|
G |
HSD11B2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions decreases activity |
EXP |
Dithiothreitol inhibits the reaction [Thiram results in decreased activity of HSD11B2 protein]; Ethylmaleimide promotes the reaction [Thiram results in decreased activity of HSD11B2 protein]; Thiram inhibits the reaction [HSD11B2 protein results in increased oxidation of Dexamethasone] |
CTD |
PMID:12901862 PMID:16857225 PMID:22796344 |
|
NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
|
|
G |
HSD3B1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases activity multiple interactions |
EXP |
Thiram results in decreased activity of HSD3B1 protein Dithiothreitol inhibits the reaction [Thiram results in decreased activity of HSD3B1 protein] |
CTD |
PMID:36965607 |
|
NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
|
|
G |
HSPA6 |
heat shock protein family A (Hsp70) member 6 |
increases expression |
EXP |
Thiram results in increased expression of HSPA6 mRNA |
CTD |
PMID:23999411 |
|
NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
|
|
G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
EXP |
Thiram promotes the reaction [TNF protein results in increased expression of ICAM1 protein] Thiram results in increased expression of ICAM1 protein |
CTD |
PMID:25752435 |
|
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
|
|
G |
IFNG |
interferon gamma |
increases expression |
ISO |
Thiram results in increased expression of IFNG protein |
CTD |
PMID:12062936 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
|
|
G |
IL18 |
interleukin 18 |
increases expression |
EXP |
Thiram results in increased expression of IL18 protein |
CTD |
PMID:23063874 |
|
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
|
|
G |
IL1A |
interleukin 1 alpha |
increases expression |
EXP |
Thiram results in increased expression of IL1A mRNA |
CTD |
PMID:33715048 |
|
NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
|
|
G |
IL1B |
interleukin 1 beta |
increases secretion |
EXP |
Thiram results in increased secretion of IL1B protein |
CTD |
PMID:33715048 |
|
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
|
|
G |
IL4 |
interleukin 4 |
increases expression |
ISO |
Thiram results in increased expression of IL4 protein |
CTD |
PMID:12062936 |
|
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
|
|
G |
LEP |
leptin |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of LEP protein |
CTD |
PMID:29321614 |
|
NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
|
|
G |
LEPR |
leptin receptor |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA |
CTD |
PMID:29321614 |
|
NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
|
|
G |
MT1G |
metallothionein 1G |
increases expression |
EXP |
Thiram results in increased expression of MT1G mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
|
|
G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
EXP |
Thiram results in increased expression of MYC mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
|
|
G |
NAMPT |
nicotinamide phosphoribosyltransferase |
increases expression |
EXP |
Thiram results in increased expression of NAMPT mRNA |
CTD |
PMID:19371601 |
|
NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
|
|
G |
NFKB1 |
nuclear factor kappa B subunit 1 |
decreases expression |
EXP |
Thiram results in decreased expression of NFKB1 mRNA |
CTD |
PMID:20385217 |
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
|
|
G |
NLRP3 |
NLR family pyrin domain containing 3 |
affects expression |
ISO |
Thiram affects the expression of NLRP3 protein |
CTD |
PMID:25929180 |
|
NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
|
|
G |
NMB |
neuromedin B |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of NMB mRNA |
CTD |
PMID:29321614 |
|
NCBI chr15:84,655,132...84,658,199
Ensembl chr15:84,655,129...84,658,563
|
|
G |
NMBR |
neuromedin B receptor |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NMBR mRNA |
CTD |
PMID:29321614 |
|
NCBI chr 6:142,074,484...142,147,122
Ensembl chr 6:142,058,330...142,147,122
|
|
G |
NPY1R |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NPY1R mRNA |
CTD |
PMID:29321614 |
|
NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
|
|
G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
EXP |
Thiram results in increased expression of NQO1 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
|
|
G |
NR3C1 |
nuclear receptor subfamily 3 group C member 1 |
multiple interactions |
EXP |
Dithiothreitol inhibits the reaction [Thiram inhibits the reaction [Dexamethasone binds to NR3C1 protein]]; Thiram inhibits the reaction [Dexamethasone binds to NR3C1 protein]; Thiram inhibits the reaction [Hydrocortisone binds to NR3C1 protein] |
CTD |
PMID:16857225 |
|
NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
|
|
G |
PARK7 |
Parkinsonism associated deglycase |
decreases activity |
EXP |
Thiram results in decreased activity of PARK7 protein |
CTD |
PMID:36842454 |
|
NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
|
|
G |
PECAM1 |
platelet and endothelial cell adhesion molecule 1 |
multiple interactions |
EXP |
Thiram inhibits the reaction [TNF protein results in decreased expression of PECAM1 protein] |
CTD |
PMID:25752435 |
|
NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
|
|
G |
PRKCA |
protein kinase C alpha |
decreases activity |
EXP |
Thiram results in decreased activity of PRKCA protein |
CTD |
PMID:15998240 |
|
NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
|
|
G |
PRKCB |
protein kinase C beta |
decreases activity |
EXP |
Thiram results in decreased activity of PRKCB protein |
CTD |
PMID:15998240 |
|
NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
|
|
G |
PRKCD |
protein kinase C delta |
increases activity |
EXP |
Thiram results in increased activity of PRKCD protein |
CTD |
PMID:15998240 |
|
NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
|
|
G |
PRKCE |
protein kinase C epsilon |
decreases activity |
EXP |
Thiram results in decreased activity of PRKCE protein |
CTD |
PMID:15998240 |
|
NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
|
|
G |
PRKCG |
protein kinase C gamma |
decreases activity |
EXP |
Thiram results in decreased activity of PRKCG protein |
CTD |
PMID:15998240 |
|
NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652
|
|
G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
EXP |
Thiram results in increased expression of PTGS2 mRNA |
CTD |
PMID:19371601 |
|
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
|
|
G |
S100P |
S100 calcium binding protein P |
increases expression |
EXP |
Thiram results in increased expression of S100P protein |
CTD |
PMID:32194361 |
|
NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170
|
|
G |
SEL1L3 |
SEL1L family member 3 |
increases expression |
EXP |
Thiram results in increased expression of SEL1L3 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 4:25,713,964...25,863,566
Ensembl chr 4:25,747,433...25,863,760
|
|
G |
SFTPA1 |
surfactant protein A1 |
multiple interactions |
EXP |
Thiram inhibits the reaction [Dexamethasone results in decreased expression of SFTPA1 mRNA] |
CTD |
PMID:16857225 |
|
NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455
|
|
G |
SFTPB |
surfactant protein B |
multiple interactions |
EXP |
Thiram inhibits the reaction [Dexamethasone results in increased expression of SFTPB mRNA] |
CTD |
PMID:16857225 |
|
NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741
|
|
G |
SLC7A11 |
solute carrier family 7 member 11 |
increases expression |
EXP |
Thiram results in increased expression of SLC7A11 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
|
|
G |
SQSTM1 |
sequestosome 1 |
increases expression |
EXP |
Thiram results in increased expression of SQSTM1 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
|
|
G |
SYNE2 |
spectrin repeat containing nuclear envelope protein 2 |
decreases expression |
EXP |
Thiram results in decreased expression of SYNE2 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr14:63,761,596...64,226,449
Ensembl chr14:63,761,899...64,226,433
|
|
G |
TGFB1 |
transforming growth factor beta 1 |
decreases activity |
EXP |
Thiram results in decreased activity of TGFB1 protein |
CTD |
PMID:31652400 |
|
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
|
|
G |
TNF |
tumor necrosis factor |
increases expression multiple interactions |
EXP |
Thiram results in increased expression of TNF mRNA Thiram inhibits the reaction [TNF protein results in decreased expression of PECAM1 protein]; Thiram inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Thiram promotes the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:20385217 PMID:25752435 |
|
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
|
|
G |
TNNT2 |
troponin T2, cardiac type |
decreases expression |
EXP |
Thiram results in decreased expression of TNNT2 mRNA |
CTD |
PMID:24211530 |
|
NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
|
|
G |
TRIM16L |
tripartite motif containing 16 like (pseudogene) |
increases expression |
EXP |
Thiram results in increased expression of TRIM16L mRNA |
CTD |
PMID:24211530 |
|
NCBI chr17:18,697,998...18,736,112
Ensembl chr17:18,722,237...18,735,460 Ensembl chr17:18,722,237...18,735,460
|
|
G |
TXNRD1 |
thioredoxin reductase 1 |
increases expression |
ISO EXP |
Thiram results in increased expression of TXNRD1 mRNA |
CTD |
PMID:23445166 PMID:24211530 |
|
NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
|
|
G |
UBA1 |
ubiquitin like modifier activating enzyme 1 |
multiple interactions |
EXP |
Thiram results in decreased activity of and results in decreased ubiquitination of UBA1 protein |
CTD |
PMID:25714994 |
|
NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
|
|
G |
VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
Thiram inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] |
CTD |
PMID:25752435 |
|
NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
|
|
|
G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
|
|
G |
ABCC3 |
ATP binding cassette subfamily C member 3 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
|
|
G |
ACOX1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA |
CTD |
PMID:32736067 |
|
NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
|
|
G |
AKT1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
ISO |
Ziram results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:30422632 |
|
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
|
|
G |
AMH |
anti-Mullerian hormone |
decreases expression increases expression |
ISO |
Ziram results in decreased expression of AMH mRNA; Ziram results in decreased expression of AMH protein Ziram results in increased expression of AMH mRNA |
CTD |
PMID:29627606 PMID:30422632 |
|
NCBI chr19:2,249,323...2,252,073
Ensembl chr19:2,249,309...2,252,073
|
|
G |
APLN |
apelin |
increases expression |
EXP |
Ziram results in increased expression of APLN mRNA |
CTD |
PMID:32870474 |
|
NCBI chr X:129,645,259...129,654,956
Ensembl chr X:129,645,259...129,654,956
|
|
G |
BAX |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Ziram results in increased expression of BAX protein |
CTD |
PMID:28973382 |
|
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
|
|
G |
BCL2 |
BCL2 apoptosis regulator |
decreases expression |
ISO |
Ziram results in decreased expression of BCL2 protein |
CTD |
PMID:28973382 |
|
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
|
|
G |
CASP1 |
caspase 1 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Dithiothreitol inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Edetic Acid inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Mercaptoethanol inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Ziram results in decreased expression of and results in increased degradation of CASP1 protein |
CTD |
PMID:25929180 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
|
|
G |
CASP3 |
caspase 3 |
increases activity |
EXP |
Ziram results in increased activity of CASP3 protein |
CTD |
PMID:20842346 PMID:22159898 |
|
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
|
|
G |
CASP8 |
caspase 8 |
increases activity |
EXP |
Ziram results in increased activity of CASP8 protein |
CTD |
PMID:22159898 |
|
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
|
|
G |
CASP9 |
caspase 9 |
increases activity |
EXP |
Ziram results in increased activity of CASP9 protein |
CTD |
PMID:22159898 |
|
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
|
|
G |
CAT |
catalase |
increases expression |
EXP |
Ziram results in increased expression of CAT mRNA |
CTD |
PMID:32712770 |
|
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
|
|
G |
CCL2 |
C-C motif chemokine ligand 2 |
decreases secretion multiple interactions |
EXP |
Ziram results in decreased secretion of CCL2 protein Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] |
CTD |
PMID:32712770 |
|
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
|
|
G |
CCND3 |
cyclin D3 |
decreases expression |
ISO |
Ziram results in decreased expression of CCND3 mRNA |
CTD |
PMID:28973382 |
|
NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
|
|
G |
CCR2 |
C-C motif chemokine receptor 2 |
decreases expression increases expression |
EXP |
Ziram results in decreased expression of CCR2 protein Ziram results in increased expression of CCR2 mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
|
|
G |
CD163 |
CD163 molecule |
decreases expression |
EXP |
Ziram results in decreased expression of CD163 mRNA; Ziram results in decreased expression of CD163 protein |
CTD |
PMID:32712770 |
|
NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893
|
|
G |
CD209 |
CD209 molecule |
increases expression |
EXP |
Ziram results in increased expression of CD209 mRNA; Ziram results in increased expression of CD209 protein |
CTD |
PMID:32712770 |
|
NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564
|
|
G |
CD36 |
CD36 molecule (CD36 blood group) |
decreases expression multiple interactions |
EXP ISO |
Ziram results in decreased expression of CD36 mRNA; Ziram results in decreased expression of CD36 protein [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA |
CTD |
PMID:32712770 PMID:32736067 |
|
NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
|
|
G |
CLEC7A |
C-type lectin domain containing 7A |
decreases expression |
EXP |
Ziram results in decreased expression of CLEC7A protein |
CTD |
PMID:32712770 |
|
NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
|
|
G |
CNN2 |
calponin 2 |
increases expression |
EXP |
Ziram results in increased expression of CNN2 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr19:1,026,608...1,039,065
Ensembl chr19:1,026,586...1,039,068
|
|
G |
CPT1A |
carnitine palmitoyltransferase 1A |
multiple interactions |
ISO |
[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA |
CTD |
PMID:32736067 |
|
NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
|
|
G |
CYCS |
cytochrome c, somatic |
affects localization |
EXP |
Ziram affects the localization of CYCS protein |
CTD |
PMID:20842346 PMID:22159898 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
|
|
G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
decreases activity affects expression decreases expression |
ISO |
Ziram results in decreased activity of CYP11A1 protein Ziram affects the expression of CYP11A1 mRNA; Ziram affects the expression of CYP11A1 protein Ziram results in decreased expression of CYP11A1 mRNA; Ziram results in decreased expression of CYP11A1 protein |
CTD |
PMID:28973382 PMID:29627606 |
|
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
|
|
G |
CYP17A1 |
cytochrome P450 family 17 subfamily A member 1 |
decreases expression affects expression decreases activity |
ISO |
Ziram results in decreased expression of CYP17A1 mRNA; Ziram results in decreased expression of CYP17A1 protein Ziram affects the expression of CYP17A1 mRNA; Ziram affects the expression of CYP17A1 protein Ziram results in decreased activity of CYP17A1 protein |
CTD |
PMID:28973382 PMID:29627606 PMID:30422632 |
|
NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
|
|
G |
CYP2B6 |
cytochrome P450 family 2 subfamily B member 6 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA |
CTD |
PMID:32736067 PMID:32745781 |
|
NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
|
|
G |
CYP2C8 |
cytochrome P450 family 2 subfamily C member 8 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
|
|
G |
DDIT3 |
DNA damage inducible transcript 3 |
increases expression |
EXP |
Ziram results in increased expression of DDIT3 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
|
|
G |
DHH |
desert hedgehog signaling molecule |
decreases expression |
ISO |
Ziram results in decreased expression of DHH mRNA; Ziram results in decreased expression of DHH protein |
CTD |
PMID:29627606 |
|
NCBI chr12:49,086,656...49,094,801
Ensembl chr12:49,086,656...49,094,801
|
|
G |
DIO1 |
iodothyronine deiodinase 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
|
|
G |
ECI1 |
enoyl-CoA delta isomerase 1 |
multiple interactions |
ISO |
[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA |
CTD |
PMID:32736067 |
|
NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300
|
|
G |
ELFN2 |
extracellular leucine rich repeat and fibronectin type III domain containing 2 |
increases expression |
EXP |
Ziram results in increased expression of ELFN2 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr22:37,340,644...37,427,479
Ensembl chr22:37,367,960...37,427,479 Ensembl chr22:37,367,960...37,427,479
|
|
G |
FCGR3A |
Fc gamma receptor IIIa |
decreases expression |
EXP |
Ziram results in decreased expression of FCGR3A protein |
CTD |
PMID:18670896 |
|
NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
|
|
G |
FCGR3B |
Fc gamma receptor IIIb |
increases expression |
EXP |
Ziram results in increased expression of FCGR3B mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 1:161,623,196...161,631,963
Ensembl chr 1:161,623,196...161,631,963
|
|
G |
FIBIN |
fin bud initiation factor homolog |
increases expression |
EXP |
Ziram results in increased expression of FIBIN mRNA |
CTD |
PMID:32870474 |
|
NCBI chr11:26,994,112...26,997,087
Ensembl chr11:26,994,112...26,997,087
|
|
G |
FSHB |
follicle stimulating hormone subunit beta |
decreases expression |
ISO |
Ziram results in decreased expression of FSHB mRNA; Ziram results in decreased expression of FSHB protein |
CTD |
PMID:28973382 PMID:30422632 |
|
NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
|
|
G |
FSHR |
follicle stimulating hormone receptor |
decreases expression |
ISO |
Ziram results in decreased expression of FSHR mRNA; Ziram results in decreased expression of FSHR protein |
CTD |
PMID:29627606 |
|
NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
|
|
G |
GFAP |
glial fibrillary acidic protein |
multiple interactions |
ISO |
[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein |
CTD |
PMID:32736067 |
|
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
|
|
G |
GNLY |
granulysin |
decreases expression |
EXP |
Ziram results in decreased expression of GNLY protein |
CTD |
PMID:22038140 |
|
NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852
|
|
G |
GZMA |
granzyme A |
decreases expression |
EXP |
Ziram results in decreased expression of GZMA protein |
CTD |
PMID:22038140 |
|
NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
|
|
G |
GZMB |
granzyme B |
decreases expression |
EXP |
Ziram results in decreased expression of GZMB protein |
CTD |
PMID:21859362 PMID:22038140 |
|
NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
|
|
G |
GZMK |
granzyme K |
decreases expression |
EXP |
Ziram results in decreased expression of GZMK protein |
CTD |
PMID:22038140 |
|
NCBI chr 5:55,024,256...55,034,570
Ensembl chr 5:55,024,256...55,034,570
|
|
G |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
|
|
G |
HMOX1 |
heme oxygenase 1 |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Ziram results in increased expression of HMOX1 protein] Ziram results in increased expression of HMOX1 mRNA; Ziram results in increased expression of HMOX1 protein |
CTD |
PMID:25714994 PMID:32712770 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
|
|
G |
HSD11B1 |
hydroxysteroid 11-beta dehydrogenase 1 |
multiple interactions decreases expression decreases activity |
ISO |
Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone]; Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP]; Ziram inhibits the reaction [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] Ziram results in decreased expression of HSD11B1 mRNA; Ziram results in decreased expression of HSD11B1 protein Ziram results in decreased activity of HSD11B1 protein |
CTD |
PMID:26859423 PMID:28973382 |
|
NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
|
|
G |
HSD11B2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions decreases activity |
EXP ISO |
Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Hydrocortisone] which results in increased chemical synthesis of Cortisone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Hydrocortisone]; Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD] Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Corticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD] |
CTD |
PMID:26859423 |
|
NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
|
|
G |
HSD17B3 |
hydroxysteroid 17-beta dehydrogenase 3 |
decreases activity decreases expression |
ISO |
Ziram results in decreased activity of HSD17B3 protein Ziram results in decreased expression of HSD17B3 mRNA; Ziram results in decreased expression of HSD17B3 protein |
CTD |
PMID:28973382 PMID:29627606 PMID:30422632 |
|
NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176
|
|
G |
HSD3B1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases activity decreases expression |
ISO |
Ziram results in decreased activity of HSD3B1 protein Ziram results in decreased expression of HSD3B1 mRNA; Ziram results in decreased expression of HSD3B1 protein |
CTD |
PMID:28973382 |
|
NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
|
|
G |
IFNB1 |
interferon beta 1 |
multiple interactions |
ISO |
Ziram inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] |
CTD |
PMID:18177342 |
|
NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
|
|
G |
IFNG |
interferon gamma |
increases expression |
ISO |
Ziram results in increased expression of IFNG protein |
CTD |
PMID:12062936 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
|
|
G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO EXP |
Ziram inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:25929180 PMID:32712770 |
|
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
|
|
G |
IL4 |
interleukin 4 |
increases expression |
ISO |
Ziram results in increased expression of IL4 protein |
CTD |
PMID:12062936 |
|
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
|
|
G |
IL6 |
interleukin 6 |
multiple interactions |
EXP |
Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:32712770 |
|
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
|
|
G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of INS1 protein |
CTD |
PMID:32745781 |
|
NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
|
|
G |
INSL3 |
insulin like 3 |
decreases expression |
ISO |
Ziram results in decreased expression of INSL3 mRNA; Ziram results in decreased expression of INSL3 protein |
CTD |
PMID:29627606 |
|
NCBI chr19:17,816,512...17,821,519
Ensembl chr19:17,816,512...17,821,574
|
|
G |
ITGAM |
integrin subunit alpha M |
increases expression |
EXP |
Ziram results in increased expression of ITGAM mRNA; Ziram results in increased expression of ITGAM protein |
CTD |
PMID:32712770 |
|
NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
|
|
G |
LEP |
leptin |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of LEP protein |
CTD |
PMID:29321614 |
|
NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
|
|
G |
LEPR |
leptin receptor |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA |
CTD |
PMID:29321614 |
|
NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
|
|
G |
LHCGR |
luteinizing hormone/choriogonadotropin receptor |
decreases expression affects expression |
ISO |
Ziram results in decreased expression of LHCGR mRNA; Ziram results in decreased expression of LHCGR protein Ziram affects the expression of LHCGR mRNA; Ziram affects the expression of LHCGR protein |
CTD |
PMID:28973382 PMID:29627606 PMID:30422632 |
|
NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
|
|
G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases activity |
EXP |
Ziram results in increased activity of MAPK1 protein |
CTD |
PMID:21859362 |
|
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
|
|
G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases activity |
EXP |
Ziram results in increased activity of MAPK3 protein |
CTD |
PMID:21859362 |
|
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
|
|
G |
MRC1 |
mannose receptor C-type 1 |
decreases expression |
EXP |
Ziram results in decreased expression of MRC1 protein |
CTD |
PMID:32712770 |
|
NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164
|
|
G |
MT1E |
metallothionein 1E |
increases expression |
EXP |
Ziram results in increased expression of MT1E mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
|
|
G |
MT1F |
metallothionein 1F |
increases expression |
EXP |
Ziram results in increased expression of MT1F mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
|
|
G |
MT1G |
metallothionein 1G |
increases expression |
EXP |
Ziram results in increased expression of MT1G mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
|
|
G |
MT1H |
metallothionein 1H |
increases expression |
EXP |
Ziram results in increased expression of MT1H mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
|
|
G |
MT1L |
metallothionein 1L (pseudogene) |
increases expression |
EXP |
Ziram results in increased expression of MT1L mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,563...56,618,680
|
|
G |
MT1X |
metallothionein 1X |
increases expression |
EXP |
Ziram results in increased expression of MT1X mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
|
|
G |
MT2A |
metallothionein 2A |
increases expression |
EXP |
Ziram results in increased expression of MT2A mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
|
|
G |
MT4 |
metallothionein 4 |
decreases expression |
EXP |
Ziram results in decreased expression of MT4 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr16:56,565,073...56,568,957
Ensembl chr16:56,565,073...56,568,957
|
|
G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
affects expression |
EXP |
Ziram affects the expression of NFE2L2 mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
|
|
G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
Ziram inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] |
CTD |
PMID:17015962 |
|
NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
|
|
G |
NLRP3 |
NLR family pyrin domain containing 3 |
decreases expression |
ISO |
Ziram results in decreased expression of NLRP3 protein |
CTD |
PMID:25929180 |
|
NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
|
|
G |
NMB |
neuromedin B |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of NMB mRNA |
CTD |
PMID:29321614 |
|
NCBI chr15:84,655,132...84,658,199
Ensembl chr15:84,655,129...84,658,563
|
|
G |
NMBR |
neuromedin B receptor |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NMBR mRNA |
CTD |
PMID:29321614 |
|
NCBI chr 6:142,074,484...142,147,122
Ensembl chr 6:142,058,330...142,147,122
|
|
G |
NPY1R |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
[2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NPY1R mRNA |
CTD |
PMID:29321614 |
|
NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
|
|
G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
multiple interactions |
ISO |
NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] |
CTD |
PMID:29950287 |
|
NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
|
|
G |
NR5A1 |
nuclear receptor subfamily 5 group A member 1 |
decreases expression affects expression |
ISO |
Ziram results in decreased expression of NR5A1 mRNA; Ziram results in decreased expression of NR5A1 protein Ziram affects the expression of NR5A1 mRNA; Ziram affects the expression of NR5A1 protein |
CTD |
PMID:28973382 PMID:29627606 |
|
NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420
|
|
G |
PARK7 |
Parkinsonism associated deglycase |
decreases activity |
EXP |
Ziram results in decreased activity of PARK7 protein |
CTD |
PMID:36842454 |
|
NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
|
|
G |
PDGFRB |
platelet derived growth factor receptor beta |
multiple interactions |
ISO |
[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein |
CTD |
PMID:32736067 |
|
NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
|
|
G |
PDK4 |
pyruvate dehydrogenase kinase 4 |
affects expression |
EXP |
Ziram affects the expression of PDK4 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
|
|
G |
PPARG |
peroxisome proliferator activated receptor gamma |
affects expression |
EXP |
Ziram affects the expression of PPARG mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
|
|
G |
PPARGC1A |
PPARG coactivator 1 alpha |
decreases expression |
ISO |
Ziram results in decreased expression of PPARGC1A protein |
CTD |
PMID:30422632 |
|
NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
|
|
G |
PRF1 |
perforin 1 |
decreases expression |
EXP |
Ziram results in decreased expression of PRF1 protein |
CTD |
PMID:21859362 PMID:22038140 |
|
NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
|
|
G |
PRSS56 |
serine protease 56 |
increases expression |
EXP |
Ziram results in increased expression of PRSS56 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr 2:232,520,388...232,525,716
Ensembl chr 2:232,520,388...232,525,716
|
|
G |
SCARB1 |
scavenger receptor class B member 1 |
decreases expression affects expression |
ISO |
Ziram results in decreased expression of SCARB1 mRNA; Ziram results in decreased expression of SCARB1 protein Ziram affects the expression of SCARB1 mRNA; Ziram affects the expression of SCARB1 protein |
CTD |
PMID:28973382 PMID:29627606 PMID:30422632 |
|
NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
|
|
G |
SERPINE1 |
serpin family E member 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
|
|
G |
SIRT1 |
sirtuin 1 |
decreases expression |
ISO |
Ziram results in decreased expression of SIRT1 protein |
CTD |
PMID:30422632 |
|
NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
|
|
G |
SLC16A2 |
solute carrier family 16 member 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr X:74,421,493...74,533,916
Ensembl chr X:74,421,493...74,533,917
|
|
G |
SLC30A1 |
solute carrier family 30 member 1 |
increases expression |
EXP |
Ziram results in increased expression of SLC30A1 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
|
|
G |
SLC30A2 |
solute carrier family 30 member 2 |
increases expression |
EXP |
Ziram results in increased expression of SLC30A2 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr 1:26,037,252...26,046,118
Ensembl chr 1:26,037,252...26,046,118
|
|
G |
SLC7A11 |
solute carrier family 7 member 11 |
increases expression |
EXP |
Ziram results in increased expression of SLC7A11 mRNA |
CTD |
PMID:32870474 |
|
NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
|
|
G |
SLC8A3 |
solute carrier family 8 member A3 |
increases response to substance decreases response to substance |
ISO |
SLC8A3 results in increased susceptibility to Ziram SLC8A3 gene mutant form results in decreased susceptibility to Ziram |
CTD |
PMID:25284465 |
|
NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480
|
|
G |
SMAD3 |
SMAD family member 3 |
multiple interactions |
EXP |
Ziram inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:31652400 |
|
NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
|
|
G |
SNCA |
synuclein alpha |
increases expression |
ISO |
Ziram results in increased expression of SNCA protein |
CTD |
PMID:18818210 |
|
NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
|
|
G |
SOD2 |
superoxide dismutase 2 |
increases expression |
EXP |
Ziram results in increased expression of SOD2 mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
|
|
G |
SOX9 |
SRY-box transcription factor 9 |
decreases expression |
ISO |
Ziram results in decreased expression of SOX9 mRNA; Ziram results in decreased expression of SOX9 protein |
CTD |
PMID:29627606 |
|
NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
|
|
G |
SRD5A1 |
steroid 5 alpha-reductase 1 |
decreases expression decreases activity |
ISO |
Ziram results in decreased expression of SRD5A1 mRNA Ziram results in decreased activity of SRD5A1 protein |
CTD |
PMID:28707553 PMID:30422632 |
|
NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539
|
|
G |
STAR |
steroidogenic acute regulatory protein |
decreases expression affects expression |
ISO |
Ziram results in decreased expression of STAR mRNA; Ziram results in decreased expression of STAR protein Ziram affects the expression of STAR mRNA; Ziram affects the expression of STAR protein |
CTD |
PMID:28973382 PMID:29627606 PMID:30422632 |
|
NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
|
|
G |
SULT1B1 |
sulfotransferase family 1B member 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA |
CTD |
PMID:32745781 |
|
NCBI chr 4:69,721,167...69,760,620
Ensembl chr 4:69,721,167...69,787,961
|
|
G |
TGFB1 |
transforming growth factor beta 1 |
decreases activity multiple interactions |
EXP |
Ziram results in decreased activity of TGFB1 protein Ziram inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:31652400 |
|
NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
|
|
G |
THRSP |
thyroid hormone responsive |
multiple interactions |
ISO |
[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] |
CTD |
PMID:32745781 |
|
NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
|
|
G |
TNF |
tumor necrosis factor |
multiple interactions |
EXP |
Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:16112155 PMID:32712770 |
|
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
|
|
G |
TPO |
thyroid peroxidase |
decreases activity |
EXP |
Ziram results in decreased activity of TPO protein |
CTD |
PMID:9248629 |
|
NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711
|
|
G |
TSPO |
translocator protein |
decreases expression |
ISO |
Ziram results in decreased expression of TSPO mRNA |
CTD |
PMID:28973382 |
|
NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
|
|
G |
UBA1 |
ubiquitin like modifier activating enzyme 1 |
decreases activity multiple interactions |
EXP |
Ziram results in decreased activity of UBA1 protein Trientine inhibits the reaction [Ziram results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; Ziram results in decreased activity of and results in decreased ubiquitination of UBA1 protein |
CTD |
PMID:18818210 PMID:25714994 |
|
NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
|
|