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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dithiocarbamic acids
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Accession:CHEBI:78787 term browser browse the term
Definition:Any organic acid in which both oxygens of a carbamic acid have been replaced by sulfur.
Synonyms:related_synonym: Formula=CHNS2R2;   SMILES=SC(=S)N([*])[*];   dithiocarbamic acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:84292



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diethyldithiocarbamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase multiple interactions
decreases activity
ISO Ditiocarb inhibits the reaction [Ditiocarb analog results in decreased activity of ALAD protein]; Ditiocarb inhibits the reaction [lead acetate results in decreased activity of ALAD protein] CTD PMID:2177232 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 increases chemical synthesis EXP ALDH3A1 protein results in increased chemical synthesis of Ditiocarb CTD PMID:18591790 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943
JBrowse link
G ANXA1 annexin A1 increases expression ISO Ditiocarb results in increased expression of ANXA1 mRNA CTD PMID:16603213 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 multiple interactions EXP [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] CTD PMID:22951949 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
JBrowse link
G APP amyloid beta precursor protein multiple interactions EXP Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP protein] CTD PMID:28242320 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G BACE1 beta-secretase 1 multiple interactions EXP Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA] CTD PMID:28242320 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
JBrowse link
G CASP1 caspase 1 multiple interactions
affects expression
ISO [Ditiocarb co-treated with Zinc] results in decreased expression of CASP1 protein
Ditiocarb affects the expression of CASP1 protein
CTD PMID:25929180 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP
[Ditiocarb co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein
[[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein]
CTD PMID:22951949 PMID:27592447 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 multiple interactions EXP [Ditiocarb binds to Copper] which results in increased activity of CASP8 protein CTD PMID:22951949 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions EXP [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein] CTD PMID:22951949 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases expression EXP Ditiocarb results in decreased expression of CAT mRNA CTD PMID:8279580 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCS copper chaperone for superoxide dismutase decreases expression ISO Ditiocarb results in decreased expression of CCS protein CTD PMID:20452388 NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression ISO Ditiocarb results in increased expression of CNP protein CTD PMID:22874009 NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740
JBrowse link
G CP ceruloplasmin multiple interactions EXP Ditiocarb inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] CTD PMID:16756764 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP [[Ditiocarb binds to Copper] which affects the localization of CYCS protein] promotes the reaction [[[CYCS protein binds to APAF1 protein binds to CASP9 protein] which results in increased metabolism of and results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein]; [Ditiocarb binds to Copper] which affects the localization of CYCS protein CTD PMID:22951949 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO
EXP
Ditiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 decreases activity EXP Ditiocarb results in decreased activity of CYP2A6 protein CTD PMID:8819299 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases activity EXP Ditiocarb results in decreased activity of CYP2C19 protein CTD PMID:8819299 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases activity
multiple interactions
ISO
EXP
Ditiocarb results in decreased activity of CYP2E1 protein
Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]; Ditiocarb inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]
[Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene; [Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene
Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of Lamotrigine]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]
CTD PMID:1356728 PMID:1538706 PMID:1664256 PMID:8558417 PMID:8560479 More... NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DDIT4 DNA damage inducible transcript 4 increases expression ISO Ditiocarb results in increased expression of DDIT4 protein CTD PMID:24764117 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 increases expression ISO Ditiocarb results in increased expression of DPYSL2 protein CTD PMID:22874009 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions ISO Ditiocarb binds to and results in decreased activity of GSTM1 protein CTD PMID:6095330 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression ISO Ditiocarb results in increased expression of GSTP1 protein CTD PMID:22874009 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO Ditiocarb results in decreased expression of HADHA protein CTD PMID:22874009 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
JBrowse link
G HBG2 hemoglobin subunit gamma 2 multiple interactions
increases expression
EXP Ditiocarb promotes the reaction [Primaquine results in increased expression of HBG2 protein]
Ditiocarb results in increased expression of HBG2 protein
CTD PMID:19616568 NCBI chr11:5,253,188...5,254,781
Ensembl chr11:5,253,188...5,505,605
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO Ditiocarb results in increased expression of HMOX1 protein CTD PMID:19467251 PMID:20452388 PMID:22874009 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity EXP Ditiocarb results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP [[Paraquat co-treated with Ditiocarb] results in decreased activity of SOD1 protein] which results in increased expression of ICAM1 protein CTD PMID:10644010 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma multiple interactions
increases expression
ISO
EXP
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased metabolism of Nitric Oxide]; Polysaccharides inhibits the reaction [Ditiocarb results in increased expression of IFNG protein]
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of APP protein]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BACE1 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN1 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN2 mRNA]; Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of Nitric Oxide]
CTD PMID:11498278 PMID:26826268 PMID:28242320 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions
ISO Ditiocarb results in increased expression of IL1B protein
Polysaccharides inhibits the reaction [Ditiocarb results in increased expression of IL1B protein]
CTD PMID:26826268 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein]; Nitric Oxide affects the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein] CTD PMID:16603213 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Ditiocarb results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]; Nitric Oxide affects the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]
CTD PMID:16603213 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MBP myelin basic protein increases expression ISO Ditiocarb results in increased expression of MBP protein CTD PMID:22874009 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO Ditiocarb inhibits the reaction [Isoflurane affects the localization of NFKB1 protein] CTD PMID:18708911 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 affects expression
multiple interactions
ISO Ditiocarb affects the expression of NLRP3 protein
[Ditiocarb co-treated with Zinc] results in decreased expression of NLRP3 protein
CTD PMID:25929180 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO
EXP
Ditiocarb inhibits the reaction [Isoflurane results in increased expression of NOS2 protein]
Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]
CTD PMID:18708911 PMID:28242320 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G PLA2G4A phospholipase A2 group IVA multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; Nitric Oxide affects the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; Nitric Oxide affects the reaction [Ditiocarb results in increased expression of PLA2G4A protein]; U 0126 inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; U 0126 inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A protein]
Ditiocarb results in increased expression of PLA2G4A mRNA; Ditiocarb results in increased expression of PLA2G4A protein
CTD PMID:16603213 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
JBrowse link
G PLN phospholamban multiple interactions
increases phosphorylation
ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ditiocarb results in increased phosphorylation of PLN protein] CTD PMID:16288776 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PRDX2 peroxiredoxin 2 increases expression ISO Ditiocarb results in increased expression of PRDX2 protein CTD PMID:22874009 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G PRDX6 peroxiredoxin 6 increases expression ISO Ditiocarb results in increased expression of PRDX6 protein CTD PMID:22874009 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
JBrowse link
G PRNP prion protein (Kanno blood group) increases expression ISO Ditiocarb results in increased expression of PRNP protein CTD PMID:20452388 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
JBrowse link
G PSEN1 presenilin 1 multiple interactions EXP Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN1 mRNA] CTD PMID:28242320 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G PSEN2 presenilin 2 multiple interactions EXP Ditiocarb inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PSEN2 mRNA] CTD PMID:28242320 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726
JBrowse link
G PYGB glycogen phosphorylase B increases expression ISO Ditiocarb results in increased expression of PYGB protein CTD PMID:22874009 NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO Ditiocarb inhibits the reaction [Isoflurane affects the localization of RELA protein] CTD PMID:18708911 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G SLC6A3 solute carrier family 6 member 3 increases expression ISO Ditiocarb results in increased expression of SLC6A3 protein CTD PMID:22874009 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
JBrowse link
G SNCA synuclein alpha increases expression ISO Ditiocarb results in increased expression of SNCA protein CTD PMID:22874009 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOD1 superoxide dismutase 1 decreases activity
increases expression
multiple interactions
EXP
ISO
Ditiocarb results in decreased activity of SOD1 protein; Ditiocarb results in decreased activity of SOD1 protein mutant form
Ditiocarb results in increased expression of SOD1 mRNA
Ditiocarb inhibits the reaction [lactacystin affects the localization of SOD1 protein mutant form]
[[Paraquat co-treated with Ditiocarb] results in decreased activity of SOD1 protein] which results in increased expression of ICAM1 protein
Ditiocarb results in increased expression of SOD1 protein
CTD PMID:8279580 PMID:10644010 PMID:15034941 PMID:16681429 PMID:19467251 More... NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO Ditiocarb results in decreased expression of and results in increased phosphorylation of TH protein CTD PMID:22874009 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO Ditiocarb inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein] CTD PMID:10486238 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
EXP Ditiocarb inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]; Ditiocarb inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]
Ditiocarb results in increased expression of TP53 protein
CTD PMID:10951577 PMID:11964141 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP
ISO
Ditiocarb results in decreased activity of and results in decreased ubiquitination of UBA1 protein
Ditiocarb binds to and results in decreased activity of UBA1 protein
CTD PMID:22874009 PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link
G UCP2 uncoupling protein 2 increases expression ISO Ditiocarb results in increased expression of UCP2 protein CTD PMID:18082129 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843
JBrowse link
ferbam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases activity EXP ferbam results in decreased activity of HSD3B1 protein CTD PMID:36965607 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
JBrowse link
G MT1G metallothionein 1G increases expression EXP ferbam results in increased expression of MT1G mRNA CTD PMID:32870474 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G TGFB1 transforming growth factor beta 1 decreases activity EXP ferbam results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
metam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions ISO methyldithiocarbamate affects the reaction [Lipopolysaccharides results in increased expression of ALS2 mRNA] CTD PMID:19339665 NCBI chr 2:201,700,267...201,780,933
Ensembl chr 2:201,700,267...201,782,112
JBrowse link
G CAT catalase multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CAT mRNA] CTD PMID:19339665 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL11 C-C motif chemokine ligand 11 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL11 protein] CTD PMID:24056979 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL2 protein] CTD PMID:24056979 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:19339665 PMID:24056979 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL4 C-C motif chemokine ligand 4 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein] CTD PMID:24056979 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL5 protein] CTD PMID:24056979 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD40 CD40 molecule multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] CTD PMID:24056979 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
JBrowse link
G CD55 CD55 molecule (Cromer blood group) multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CD55 mRNA] CTD PMID:24056979 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
JBrowse link
G CFB complement factor B multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CFB mRNA] CTD PMID:24056979 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
JBrowse link
G CLEC2D C-type lectin domain family 2 member D multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CLEC2D mRNA] CTD PMID:24056979 NCBI chr12:9,669,713...9,699,553
Ensembl chr12:9,664,969...9,699,553
JBrowse link
G CLEC7A C-type lectin domain containing 7A multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC7A mRNA] CTD PMID:24056979 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CRTAM mRNA] CTD PMID:24056979 NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643
JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] CTD PMID:19339665 PMID:24056979 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CTSB cathepsin B multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CTSB mRNA] CTD PMID:19339665 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL9 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CXCL9 protein] CTD PMID:16321413 PMID:24056979 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G DHX58 DExH-box helicase 58 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of DHX58 mRNA] CTD PMID:24056979 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of EIF2AK2 mRNA] CTD PMID:24056979 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522
JBrowse link
G EREG epiregulin multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of EREG mRNA] CTD PMID:24056979 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749
JBrowse link
G FCGR1A Fc gamma receptor Ia multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of FCGR1 mRNA] CTD PMID:24056979 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675
JBrowse link
G GAB1 GRB2 associated binding protein 1 multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GAB1 mRNA] CTD PMID:19339665 NCBI chr 4:143,336,876...143,474,565
Ensembl chr 4:143,336,876...143,474,565
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GCLM mRNA] CTD PMID:19339665 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GPX3 glutathione peroxidase 3 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of GPX3 mRNA] CTD PMID:19339665 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA] CTD PMID:19339665 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IDH1 mRNA] CTD PMID:19339665 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IFI16 interferon gamma inducible protein 16 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI204 mRNA] CTD PMID:24056979 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155
JBrowse link
G IFIH1 interferon induced with helicase C domain 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIH1 mRNA] CTD PMID:24056979 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
JBrowse link
G IFIT1B interferon induced protein with tetratricopeptide repeats 1B multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT1 mRNA] CTD PMID:24056979 NCBI chr10:89,378,056...89,385,205
Ensembl chr10:89,378,056...89,385,205
JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT2 mRNA] CTD PMID:24056979 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA] CTD PMID:24056979 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473
JBrowse link
G IFNA8 interferon alpha 8 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNA2 mRNA] CTD PMID:24056979 NCBI chr 9:21,409,117...21,410,185
Ensembl chr 9:21,409,117...21,410,185
JBrowse link
G IFNB1 interferon beta 1 multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:24056979 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
JBrowse link
G IFNG interferon gamma multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] CTD PMID:15933225 PMID:19339665 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 multiple interactions ISO [Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased expression of IL10 mRNA; [Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased secretion of IL10 protein; [methyldithiocarbamate binds to Copper] promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; [Nadolol co-treated with Mifepristone] promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; Buthionine Sulfoximine promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL12A interleukin 12A multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:15933225 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
JBrowse link
G IL12B interleukin 12B multiple interactions ISO [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL18 interleukin 18 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] CTD PMID:15933225 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:15933225 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:15933225 PMID:19339665 PMID:24056979 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions ISO Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:19339665 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRF3 interferon regulatory factor 3 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF3 mRNA] CTD PMID:24056979 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875
JBrowse link
G IRF4 interferon regulatory factor 4 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF4 mRNA] CTD PMID:24056979 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G IRF5 interferon regulatory factor 5 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF5 mRNA] CTD PMID:24056979 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038
JBrowse link
G IRF7 interferon regulatory factor 7 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF7 mRNA] CTD PMID:24056979 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
JBrowse link
G IRGM immunity related GTPase M multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRGM1 mRNA] CTD PMID:24056979 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736
JBrowse link
G ISG15 ISG15 ubiquitin like modifier multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of ISG15 mRNA] CTD PMID:24056979 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G KLRK1 killer cell lectin like receptor K1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of KLRK1 mRNA] CTD PMID:24056979 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874
JBrowse link
G MALT1 MALT1 paracaspase multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MALT1 mRNA] CTD PMID:24056979 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:15933225 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] CTD PMID:15933225 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:15933225 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:15933225 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MASP1 MBL associated serine protease 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MASP1 mRNA] CTD PMID:24056979 NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
JBrowse link
G MBL2 mannose binding lectin 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MBL2 mRNA] CTD PMID:24056979 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MIF macrophage migration inhibitory factor multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MIF mRNA] CTD PMID:15933225 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MTF1 metal regulatory transcription factor 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MTF1 mRNA] CTD PMID:19339665 NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592
JBrowse link
G MX1 MX dynamin like GTPase 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX1 mRNA] CTD PMID:24056979 NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071
JBrowse link
G MX2 MX dynamin like GTPase 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX2 mRNA] CTD PMID:24056979 NCBI chr21:41,362,027...41,409,393
Ensembl chr21:41,361,999...41,409,393
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA] CTD PMID:24056979 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G MYO1F myosin IF multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MYO1F mRNA] CTD PMID:24056979 NCBI chr19:8,520,778...8,577,442
Ensembl chr19:8,520,778...8,577,442
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA] CTD PMID:24056979 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NOD1 mRNA] CTD PMID:24056979 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PPP1R15B mRNA] CTD PMID:19339665 NCBI chr 1:204,395,826...204,411,817
Ensembl chr 1:204,396,492...204,411,887
JBrowse link
G PRDX1 peroxiredoxin 1 multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PRDX1 mRNA] CTD PMID:19339665 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PRNP prion protein (Kanno blood group) multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PRNP mRNA] CTD PMID:19339665 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
JBrowse link
G PSMB5 proteasome 20S subunit beta 5 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB5 mRNA] CTD PMID:19339665 NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230
JBrowse link
G RIGI RNA sensor RIG-I multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIGI mRNA] CTD PMID:24056979 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA] CTD PMID:24056979 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA] CTD PMID:19339665 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SRXN1 sulfiredoxin 1 multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of SRXN1 mRNA] CTD PMID:19339665 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA] CTD PMID:24056979 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G STAT5A signal transducer and activator of transcription 5A multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT5A mRNA] CTD PMID:24056979 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
JBrowse link
G TIRAP TIR domain containing adaptor protein multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TIRAP mRNA] CTD PMID:24056979 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845
JBrowse link
G TLR3 toll like receptor 3 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TLR3 mRNA] CTD PMID:24056979 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:19339665 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TOR1AIP2 torsin 1A interacting protein 2 multiple interactions ISO methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of TOR1AIP2 mRNA] CTD PMID:24056979 NCBI chr 1:179,839,976...179,877,803
Ensembl chr 1:179,839,967...179,877,803
JBrowse link
G TXNRD2 thioredoxin reductase 2 multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of TXNRD2 mRNA] CTD PMID:19339665 NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP methyldithiocarbamate results in increased activity of and results in increased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link
G XPA XPA, DNA damage recognition and repair factor multiple interactions ISO methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of XPA mRNA] CTD PMID:19339665 NCBI chr 9:97,654,398...97,697,340
Ensembl chr 9:97,674,909...97,697,340
JBrowse link
pyrrolidine dithiocarbamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1] CTD PMID:10636889 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:15078482 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G ACTB actin beta multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] CTD PMID:15477007 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G AGT angiotensinogen multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] CTD PMID:10712386 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions
decreases expression
ISO pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the expression of AIF1 protein]
pyrrolidine dithiocarbamic acid results in decreased expression of AIF1 protein
CTD PMID:36682417 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased phosphorylation of AKT1 protein] CTD PMID:24431215 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALB albumin multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased abundance of Hydrogen Peroxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA] CTD PMID:11961005 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ALDH2 mRNA] CTD PMID:11578593 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions EXP cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein] CTD PMID:34575692 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO pyrrolidine dithiocarbamic acid results in decreased susceptibility to [APP protein modified form binds to APP protein modified form] CTD PMID:17409235 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G AR androgen receptor multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR protein] CTD PMID:16139439 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha decreases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in decreased expression of ARHGDIA mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA
CTD PMID:15477007 NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,721...81,871,378
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] CTD PMID:15477007 NCBI chr 2:218,217,189...218,254,348
Ensembl chr 2:218,217,141...218,254,356
JBrowse link
G ATF4 activating transcription factor 4 multiple interactions EXP
ISO
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA]
CTD PMID:15477007 PMID:20920558 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G ATP7A ATPase copper transporting alpha decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of ATP7A CTD PMID:25070243 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395
JBrowse link
G BAK1 BCL2 antagonist/killer 1 multiple interactions ISO [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein] CTD PMID:22085843 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein] CTD PMID:22085843 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator increases phosphorylation
multiple interactions
EXP
ISO
pyrrolidine dithiocarbamic acid results in increased phosphorylation of BCL2 protein
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BCL2 mRNA]
CTD PMID:12482581 PMID:16139439 PMID:20920558 PMID:21161674 PMID:22085843 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2A1 BCL2 related protein A1 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA] CTD PMID:15477007 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BCL2L1 protein]
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein]
CTD PMID:18789402 PMID:22085843 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein] CTD PMID:22261313 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein multiple interactions EXP cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA] CTD PMID:34575692 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] CTD PMID:14527959 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions
decreases expression
EXP pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]
pyrrolidine dithiocarbamic acid results in decreased expression of BIRC5 protein
CTD PMID:16139439 PMID:21161674 PMID:29541389 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CASP1 caspase 1 multiple interactions ISO
EXP
pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form]
pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased cleavage of CASP1 protein]
CTD PMID:31586597 PMID:35190838 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP
pyrrolidine dithiocarbamic acid inhibits the reaction [Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein]
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein]
[pyrrolidine dithiocarbamic acid binds to Copper] which results in increased activity of CASP3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased activity of CASP3 protein]
CTD PMID:10941151 PMID:18671963 PMID:20920558 PMID:21687928 PMID:22085843 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 multiple interactions ISO [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein] CTD PMID:20920558 PMID:22085843 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] CTD PMID:15477007 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity
ISO
EXP
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]
pyrrolidine dithiocarbamic acid results in increased activity of CASP9 protein
CTD PMID:12198114 PMID:20920558 PMID:22085843 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]
CTD PMID:11006087 PMID:11961005 PMID:12016129 PMID:12472797 PMID:16129981 More... NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL20 C-C motif chemokine ligand 20 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL20 mRNA] CTD PMID:11578593 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCL23 C-C motif chemokine ligand 23 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL9 mRNA] CTD PMID:22225513 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] CTD PMID:15477007 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL3L1 C-C motif chemokine ligand 3 like 1 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3L1 mRNA] CTD PMID:15477007 Ensembl chr17:36,194,869...36,196,758 JBrowse link
G CCL4 C-C motif chemokine ligand 4 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 protein] CTD PMID:16129981 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 PMID:22225513 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
pyrrolidine dithiocarbamic acid results in decreased expression of CCND1 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of CCND1 mRNA]
CTD PMID:14603533 PMID:31048002 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNE1 cyclin E1 decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of CCNE1 protein CTD PMID:14603533 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CCNG1 cyclin G1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] CTD PMID:15477007 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] CTD PMID:15477007 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CD14 CD14 molecule multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in decreased expression of CD14 mRNA]
CTD PMID:20368581 PMID:36539177 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD200 CD200 molecule multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] CTD PMID:15477007 NCBI chr 3:112,332,573...112,362,812
Ensembl chr 3:112,332,347...112,362,812
JBrowse link
G CD44 CD44 molecule (IN blood group) multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] CTD PMID:15477007 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CDH1 cadherin 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of CDH1 protein] CTD PMID:36722465 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDH17 cadherin 17 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] CTD PMID:15477007 NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303
JBrowse link
G CDH2 cadherin 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CDH2 protein] CTD PMID:36722465 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of CDK2 protein CTD PMID:14603533 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of CDK4 protein CTD PMID:14603533 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in decreased expression of CDKN1A mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein]
CTD PMID:14603533 PMID:15048878 PMID:31048002 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1B protein] CTD PMID:15048878 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CEBPB CCAAT enhancer binding protein beta increases response to substance
multiple interactions
EXP CEBPB results in increased susceptibility to pyrrolidine dithiocarbamic acid
pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter]
CTD PMID:9359698 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:11739238 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
JBrowse link
G CLEC10A C-type lectin domain containing 10A multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC10A mRNA] CTD PMID:17342418 NCBI chr17:7,074,537...7,080,251
Ensembl chr17:7,074,537...7,080,307
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] CTD PMID:15477007 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNR2 cannabinoid receptor 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G CNTNAP1 contactin associated protein 1 increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of CNTNAP1 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA
CTD PMID:15477007 NCBI chr17:42,682,531...42,699,993
Ensembl chr17:42,682,531...42,699,993
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO
EXP
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]
cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of COL1A1 mRNA]
CTD PMID:15078482 PMID:34575692 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL1A2 collagen type I alpha 2 chain multiple interactions EXP atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]] CTD PMID:34152691 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G COL6A1 collagen type VI alpha 1 chain multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] CTD PMID:15477007 NCBI chr21:45,981,770...46,005,048
Ensembl chr21:45,981,770...46,005,050
JBrowse link
G COMT catechol-O-methyltransferase multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] CTD PMID:15477007 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link
G CP ceruloplasmin multiple interactions
increases secretion
increases expression
EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]
pyrrolidine dithiocarbamic acid results in increased secretion of CP protein
pyrrolidine dithiocarbamic acid results in increased expression of CP mRNA; pyrrolidine dithiocarbamic acid results in increased expression of CP protein
CTD PMID:17032174 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CPSF1 cleavage and polyadenylation specific factor 1 multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of CPSF1 mRNA
CTD PMID:15477007 NCBI chr 8:144,393,231...144,409,335
Ensembl chr 8:144,393,229...144,409,335
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA CTD PMID:15477007 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CREM cAMP responsive element modulator multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] CTD PMID:15477007 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CTBP1 C-terminal binding protein 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] CTD PMID:15477007 NCBI chr 4:1,211,445...1,250,355
Ensembl chr 4:1,211,445...1,250,333
JBrowse link
G CUL5 cullin 5 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] CTD PMID:15477007 NCBI chr11:108,008,898...108,107,761
Ensembl chr11:108,008,898...108,107,761
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL1 mRNA] CTD PMID:16129981 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of CXCL10 mRNA] CTD PMID:36539177 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein]
CTD PMID:16129981 PMID:21507677 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP
ISO
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]]; pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzene results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzo(a)pyrene results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [chromium hexavalent ion results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [PLA2G1B protein results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Vehicle Emissions results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]]
pyrrolidine dithiocarbamic acid inhibits the reaction [CPG-oligonucleotide results in increased expression of CXCL8]
CTD PMID:11306435 PMID:12016129 PMID:15528384 PMID:19626664 PMID:21779360 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP
ISO
[pyrrolidine dithiocarbamic acid binds to Copper] which affects the localization of CYCS protein
[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein]
CTD PMID:18671963 PMID:20920558 PMID:22085843 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
CTD PMID:9756946 PMID:18078826 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2A13 cytochrome P450 family 2 subfamily A member 13 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP2A13 mRNA] CTD PMID:23884085 NCBI chr19:41,088,451...41,096,195
Ensembl chr19:41,088,451...41,096,195
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [aflatoxin G1 results in increased expression of CYP2E1 protein] CTD PMID:36997055 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [Fenretinide results in increased expression of DDIT3 protein]
pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]
CTD PMID:16972258 PMID:20920558 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of DNAJB1 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA
CTD PMID:15477007 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391
JBrowse link
G DUSP4 dual specificity phosphatase 4 multiple interactions EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] CTD PMID:15477007 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684
JBrowse link
G EGF epidermal growth factor multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] CTD PMID:16340751 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP
ISO
[Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein
pyrrolidine dithiocarbamic acid affects the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of EGFR protein]
CTD PMID:18346929 PMID:38003411 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA]; SB 203580 promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA] CTD PMID:12482581 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EGR2 early growth response 2 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] CTD PMID:15477007 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
JBrowse link
G EGR3 early growth response 3 multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of EGR3 mRNA
CTD PMID:15477007 NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [pervanadate results in increased cleavage of ERBB4 protein] CTD PMID:9685416 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] CTD PMID:17141290 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FN1 fibronectin 1 multiple interactions EXP atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]] CTD PMID:12388107 PMID:34152691 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of FOS mRNA
pyrrolidine dithiocarbamic acid results in increased expression of FOS protein
CTD PMID:7539260 PMID:15477007 PMID:17032174 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] CTD PMID:15477007 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317
JBrowse link
G FYB1 FYN binding protein 1 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] CTD PMID:15477007 NCBI chr 5:39,105,252...39,274,528
Ensembl chr 5:39,105,252...39,274,528
JBrowse link
G G3BP2 G3BP stress granule assembly factor 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein] CTD PMID:28816235 NCBI chr 4:75,642,786...75,724,437
Ensembl chr 4:75,641,849...75,724,589
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase increases expression ISO pyrrolidine dithiocarbamic acid results in increased expression of GAPDH mRNA CTD PMID:11108245 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GATA1 GATA binding protein 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] CTD PMID:10656287 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,540...48,794,311
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of GFAP mRNA] CTD PMID:36539177 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GFRA2 GDNF family receptor alpha 2 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] CTD PMID:15477007 NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357
JBrowse link
G GNAS GNAS complex locus multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA CTD PMID:15477007 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
JBrowse link
G GNLY granulysin multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNLY mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNLY mRNA] CTD PMID:15477007 NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein] CTD PMID:22645130 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions ISO pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the expression of AIF1 protein]; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] CTD PMID:34082047 PMID:36682417 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GSK3B glycogen synthase kinase 3 beta increases phosphorylation ISO pyrrolidine dithiocarbamic acid results in increased phosphorylation of GSK3B protein CTD PMID:17409235 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GTF2H2C GTF2H2 family member C multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA CTD PMID:15477007 NCBI chr 5:69,560,191...69,595,221
Ensembl chr 5:69,560,191...69,595,221
Ensembl chr 5:69,560,191...69,595,221
JBrowse link
G GZMA granzyme A multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA] CTD PMID:12700414 NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
JBrowse link
G GZMB granzyme B multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA] CTD PMID:12700414 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein]] CTD PMID:36997055 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] CTD PMID:15477007 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
JBrowse link
G HARS1 histidyl-tRNA synthetase 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] CTD PMID:15477007 NCBI chr 5:140,673,905...140,691,370
Ensembl chr 5:140,673,035...140,691,537
JBrowse link
G HCK HCK proto-oncogene, Src family tyrosine kinase multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] CTD PMID:15477007 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856
JBrowse link
G HLA-B major histocompatibility complex, class I, B multiple interactions EXP [HLA-B protein alternative form co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of and affects the localization of RELA protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of HLA-B protein alternative form; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of PSMB9 protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of TAP1 protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of IL1B protein; [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of TNF protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of HLA-B protein alternative form]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of TAP1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of TNF protein] CTD PMID:36423715 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067
JBrowse link
G HMBS hydroxymethylbilane synthase multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] CTD PMID:10656287 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834
JBrowse link
G HMGB1 high mobility group box 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] CTD PMID:15477007 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMGCS2 mRNA] CTD PMID:11578593 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases stability
increases expression
EXP
ISO
pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 protein]
pyrrolidine dithiocarbamic acid results in increased stability of HMOX1 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 protein
pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Lead results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]
CTD PMID:9837857 PMID:16972258 PMID:18078826 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA CTD PMID:15477007 NCBI chr19:41,262,557...41,307,787
Ensembl chr19:41,262,496...41,307,787
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity EXP pyrrolidine dithiocarbamic acid results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] CTD PMID:20920558 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] CTD PMID:20920558 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of HSPA8 mRNA
CTD PMID:15477007 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HYAL3 hyaluronidase 3 multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA CTD PMID:15477007 NCBI chr 3:50,292,832...50,299,405
Ensembl chr 3:50,292,831...50,299,405
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
decreases expression
EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of ICAM1 mRNA
CTD PMID:10495789 PMID:12131776 PMID:14572618 PMID:16129981 PMID:17416599 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma multiple interactions ISO
EXP
pyrrolidine dithiocarbamic acid inhibits the reaction [IFNG protein results in increased abundance of Nitrites]
pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein]
CTD PMID:8903404 PMID:12845421 PMID:18039960 PMID:25766886 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNGR2 interferon gamma receptor 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] CTD PMID:15477007 NCBI chr21:33,402,882...33,437,516
Ensembl chr21:33,403,413...33,479,348
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of IKBKB protein] CTD PMID:26860689 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460
JBrowse link
G IL10 interleukin 10 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased expression of IL10 mRNA] CTD PMID:11124598 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL12B interleukin 12B multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15778123 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL17A interleukin 17A multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA] CTD PMID:12016129 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] CTD PMID:15178407 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP
ISO
[pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of IL1B protein; pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased secretion of IL1B protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased abundance of 8-epi-prostaglandin F2alpha]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form]
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of IL1B protein]
CTD PMID:7539260 PMID:8662662 PMID:11530235 PMID:11578593 PMID:11970852 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL2 interleukin 2 multiple interactions EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA]
CTD PMID:12700414 PMID:15477007 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL2RB interleukin 2 receptor subunit beta multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] CTD PMID:15477007 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118
JBrowse link
G IL6 interleukin 6 multiple interactions
decreases secretion
ISO
EXP
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]
pyrrolidine dithiocarbamic acid results in decreased secretion of IL6 protein
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]
CTD PMID:11970852 PMID:12016129 PMID:21779360 PMID:23535185 PMID:23665308 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRF1 interferon regulatory factor 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 protein] CTD PMID:11739238 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G IRF4 interferon regulatory factor 4 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] CTD PMID:15477007 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]
pyrrolidine dithiocarbamic acid results in increased expression of JUN mRNA; pyrrolidine dithiocarbamic acid results in increased expression of JUN protein
CTD PMID:12482581 PMID:15477007 PMID:17032174 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KL klotho multiple interactions
increases expression
EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL protein]
pyrrolidine dithiocarbamic acid results in increased expression of KL protein
CTD PMID:21389697 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G KLF4 KLF transcription factor 4 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] CTD PMID:15477007 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G KLF6 KLF transcription factor 6 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] CTD PMID:15477007 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
JBrowse link
G KLK3 kallikrein related peptidase 3 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of KLK3 mRNA] CTD PMID:16139439 NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764
JBrowse link
G LCMT2 leucine carboxyl methyltransferase 2 increases expression
multiple interactions
increases response to substance
EXP
ISO
pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 protein
LCMT2 results in increased susceptibility to [pyrrolidine dithiocarbamic acid co-treated with Fluorouracil]
LCMT2 results in increased susceptibility to pyrrolidine dithiocarbamic acid
pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter]
CTD PMID:9359698 NCBI chr15:43,323,649...43,330,573
Ensembl chr15:43,323,649...43,330,582
JBrowse link
G LCN2 lipocalin 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of LCN2 mRNA] CTD PMID:36539177 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LCP1 lymphocyte cytosolic protein 1 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] CTD PMID:15477007 NCBI chr13:46,125,923...46,182,177
Ensembl chr13:46,125,920...46,211,871
JBrowse link
G LIF LIF interleukin 6 family cytokine multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of LIF mRNA] CTD PMID:11578593 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
JBrowse link
G LTBP4 latent transforming growth factor beta binding protein 4 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] CTD PMID:15477007 NCBI chr19:40,593,166...40,629,820
Ensembl chr19:40,592,883...40,629,818
JBrowse link
G MADCAM1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] CTD PMID:12388057 NCBI chr19:496,486...505,343
Ensembl chr19:489,176...505,343
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 multiple interactions ISO [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein] CTD PMID:22085843 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases activity
EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]
pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; Glutathione inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the susceptibility to [Copper co-treated with pyrrolidine dithiocarbamic acid]
CTD PMID:10658192 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein]
CTD PMID:10941151 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases activity
ISO [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]
pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein
CTD PMID:10658192 PMID:10941151 PMID:20920558 PMID:22085843 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO
EXP
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]
CTD PMID:15557793 PMID:22085843 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MAPT microtubule associated protein tau decreases phosphorylation ISO pyrrolidine dithiocarbamic acid results in decreased phosphorylation of MAPT protein CTD PMID:17409235 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
JBrowse link
G MIR146A microRNA 146a multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA] CTD PMID:22099153 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
JBrowse link
G MLXIP MLX interacting protein multiple interactions ISO
EXP
pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of MLXIP protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of MLXIP protein]
CTD PMID:33930463 NCBI chr12:122,078,756...122,147,344
Ensembl chr12:122,078,756...122,147,344
JBrowse link
G MMP1 matrix metallopeptidase 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]] CTD PMID:32613688 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [CPG-oligonucleotide results in increased secretion of MMP13 protein] CTD PMID:23331101 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP2 matrix metallopeptidase 2 decreases expression
multiple interactions
EXP
ISO
pyrrolidine dithiocarbamic acid results in decreased expression of MMP2 mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of MMP2 mRNA]
CTD PMID:19272247 PMID:23566884 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 decreases activity
multiple interactions
decreases expression
EXP pyrrolidine dithiocarbamic acid results in decreased activity of MMP9 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of MMP9 mRNA
CTD PMID:16340751 PMID:22033475 PMID:23566884 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MPO myeloperoxidase multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased activity of MPO protein] CTD PMID:12879239 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MST1R macrophage stimulating 1 receptor decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of MST1R mRNA CTD PMID:18593918 NCBI chr 3:49,887,002...49,903,873
Ensembl chr 3:49,887,002...49,903,873
JBrowse link
G MT1B metallothionein 1B increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of MT1B mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1B mRNA
CTD PMID:15477007 NCBI chr16:56,651,886...56,653,204
Ensembl chr16:56,651,886...56,653,204
JBrowse link
G MT1E metallothionein 1E increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of MT1E mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1E mRNA
CTD PMID:15477007 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
JBrowse link
G MT1F metallothionein 1F multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1F mRNA
pyrrolidine dithiocarbamic acid results in increased expression of MT1F mRNA
CTD PMID:15477007 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT1G metallothionein 1G increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of MT1G mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1G mRNA
CTD PMID:15477007 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MT1H metallothionein 1H multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1H mRNA CTD PMID:15477007 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
JBrowse link
G MT1X metallothionein 1X increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of MT1X mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1X mRNA
CTD PMID:15477007 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MTA1 metastasis associated 1 multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MTA1 mRNA CTD PMID:15477007 NCBI chr14:105,419,827...105,470,729
Ensembl chr14:105,419,820...105,470,729
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]] CTD PMID:34152691 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of MYC mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of MYC
CTD PMID:15477007 PMID:21161674 PMID:25070243 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYH1 myosin heavy chain 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MYH1 protein] CTD PMID:24431215 NCBI chr17:10,492,307...10,518,542
Ensembl chr17:10,492,307...10,518,542
JBrowse link
G MYH7 myosin heavy chain 7 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein] CTD PMID:28816235 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
JBrowse link
G NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA] CTD PMID:15477007 NCBI chr 3:50,296,402...50,299,405
Ensembl chr 3:50,296,402...50,299,416
JBrowse link
G NELL1 neural EGFL like 1 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA] CTD PMID:15477007 NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686
JBrowse link
G NFE2 nuclear factor, erythroid 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] CTD PMID:10656287 NCBI chr12:54,292,111...54,301,015
Ensembl chr12:54,292,111...54,301,015
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of NFE2L2 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of NFE2L2 mRNA
CTD PMID:15477007 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]
CTD PMID:10416616 PMID:11006087 PMID:11286985 PMID:11578593 PMID:11739238 More... NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] CTD PMID:25559736 NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
decreases expression
EXP
ISO
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]
pyrrolidine dithiocarbamic acid results in decreased expression of NFKBIA mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of NFKBIA protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NFKBIA protein]
CTD PMID:9434740 PMID:10636889 PMID:10921504 PMID:11006087 PMID:11739238 More... NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NGF nerve growth factor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein] CTD PMID:17651887 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NGFR nerve growth factor receptor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein] CTD PMID:17651887 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G NKG7 natural killer cell granule protein 7 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] CTD PMID:15477007 NCBI chr19:51,371,620...51,372,654
Ensembl chr19:51,371,606...51,372,701
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased expression of NLRP3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [swietenine inhibits the reaction [Glucose results in increased expression of NLRP3 protein]] CTD PMID:35190838 PMID:36066211 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NMI N-myc and STAT interactor multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA] CTD PMID:15477007 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of NOS2 mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [[Ozone results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ozone results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased expression of NOS2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [resveratrol results in decreased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [resveratrol results in decreased expression of NOS2 protein]
CTD PMID:7539260 PMID:8662662 PMID:8903404 PMID:9788894 PMID:11530235 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOTCH3 notch receptor 3 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] CTD PMID:15477007 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
G NPPA natriuretic peptide A multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA protein] CTD PMID:28816235 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB protein] CTD PMID:28816235 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA] CTD PMID:15477007 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891
JBrowse link
G ODC1 ornithine decarboxylase 1 multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ODC1 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of ODC1 mRNA
CTD PMID:15477007 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PAX8 paired box 8 multiple interactions
decreases expression
decreases chemical synthesis
ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter]
pyrrolidine dithiocarbamic acid results in decreased chemical synthesis of PAX8 protein
CTD PMID:11108245 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of PCNA mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of PCNA protein]
CTD PMID:31048002 PMID:38003411 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PLA2G1B phospholipase A2 group IB multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [PLA2G1B protein results in increased expression of CXCL8 protein] CTD PMID:15528384 NCBI chr12:120,322,115...120,327,779
Ensembl chr12:120,322,115...120,327,779
JBrowse link
G PLAU plasminogen activator, urokinase multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] CTD PMID:16340751 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PNPLA4 patatin like phospholipase domain containing 4 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] CTD PMID:15477007 NCBI chr  X:7,898,247...7,927,724
Ensembl chr  X:7,898,247...7,927,739
JBrowse link
G POU2F2 POU class 2 homeobox 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] CTD PMID:15477007 NCBI chr19:42,086,110...42,197,936
Ensembl chr19:42,086,110...42,196,585
JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of PPP1CA mRNA CTD PMID:15477007 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183
JBrowse link
G PPP1R10 protein phosphatase 1 regulatory subunit 10 increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of PPP1R10 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of PPP1R10 mRNA
CTD PMID:15477007 NCBI chr 6:30,600,413...30,617,243
Ensembl chr 6:30,600,413...30,618,612
JBrowse link
G PRF1 perforin 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA] CTD PMID:12700414 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
JBrowse link
G PSMB8 proteasome 20S subunit beta 8 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB8 protein] CTD PMID:36423715 NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of PSMB9 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB9 protein] CTD PMID:36423715 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Homocysteine results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [sodium arsenite results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]
CTD PMID:8662662 PMID:11530235 PMID:11835400 PMID:16765938 PMID:17767925 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RAC1 Rac family small GTPase 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA] CTD PMID:12719791 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RBBP4 RB binding protein 4, chromatin remodeling factor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in decreased expression of RBBP4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in decreased expression of RBBP4 protein] CTD PMID:37866543 NCBI chr 1:32,651,208...32,686,211
Ensembl chr 1:32,651,142...32,686,211
JBrowse link
G REL REL proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of REL protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of REL protein]
CTD PMID:11970852 PMID:15477007 PMID:26860689 NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity
EXP
ISO
[HLA-B protein alternative form co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of and affects the localization of RELA protein; pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Imatinib Mesylate results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Resveratrol affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid promotes the reaction [andrographolide results in decreased expression of and results in decreased localization of RELA protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [swietenine inhibits the reaction [Glucose results in increased expression of RELA protein]]; Resveratrol promotes the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of RELA]
pyrrolidine dithiocarbamic acid inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein]
pyrrolidine dithiocarbamic acid results in decreased activity of RELA protein
CTD PMID:10416616 PMID:11739238 PMID:11961005 PMID:11970852 PMID:12016129 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] CTD PMID:11970852 NCBI chr19:45,001,464...45,038,192
Ensembl chr19:45,001,461...45,038,192
JBrowse link
G RHOG ras homolog family member G multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] CTD PMID:15477007 NCBI chr11:3,826,978...3,840,959
Ensembl chr11:3,826,978...3,840,959
JBrowse link
G RNASET2 ribonuclease T2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] CTD PMID:15477007 NCBI chr 6:166,922,113...166,956,550
Ensembl chr 6:166,922,113...166,957,191
JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA] CTD PMID:34575692 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SART1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] CTD PMID:15477007 NCBI chr11:65,961,734...65,980,137
Ensembl chr11:65,961,728...65,980,137
JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions
increases expression
EXP pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of SERPINE1 mRNA
CTD PMID:12719791 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SF3B4 splicing factor 3b subunit 4 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] CTD PMID:15477007 NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803
JBrowse link
G SFTPC surfactant protein C multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of SFTPC protein] CTD PMID:28070109 NCBI chr 8:22,157,383...22,164,479
Ensembl chr 8:22,156,913...22,164,479
JBrowse link
G SLA Src like adaptor multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] CTD PMID:15477007 NCBI chr 8:133,036,728...133,102,602
Ensembl chr 8:133,036,728...133,102,912
JBrowse link
G SLC1A2 solute carrier family 1 member 2 increases expression
multiple interactions
ISO pyrrolidine dithiocarbamic acid results in increased expression of SLC1A2 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 protein]
CTD PMID:17409235 PMID:22645130 PMID:24782323 NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
JBrowse link
G SLC1A3 solute carrier family 1 member 3 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 protein] CTD PMID:24782323 NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
JBrowse link
G SLC3A2 solute carrier family 3 member 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] CTD PMID:15477007 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SNRNP70 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of SNRNP70 mRNA
CTD PMID:15477007 NCBI chr19:49,085,451...49,108,604
Ensembl chr19:49,085,419...49,108,605
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
decreases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SOD1 mRNA
pyrrolidine dithiocarbamic acid results in decreased expression of SOD1 mRNA
CTD PMID:15477007 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases expression
EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of SOD2 mRNA
CTD PMID:9434740 PMID:10653605 PMID:12031898 PMID:22261313 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SP7 Sp7 transcription factor multiple interactions EXP cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of SP7 mRNA] CTD PMID:34575692 NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315
JBrowse link
G SPP1 secreted phosphoprotein 1 decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of SPP1 CTD PMID:21076490 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SRGN serglycin multiple interactions
increases expression
EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SRGN mRNA
pyrrolidine dithiocarbamic acid results in increased expression of SRGN mRNA
CTD PMID:15477007 NCBI chr10:69,087,603...69,104,811
Ensembl chr10:69,088,103...69,104,805
JBrowse link
G SRI sorcin multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose results in decreased expression of SRI protein] CTD PMID:33930463 NCBI chr 7:88,205,115...88,226,976
Ensembl chr 7:88,205,115...88,226,993
JBrowse link
G SRPRA SRP receptor subunit alpha multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA] CTD PMID:15477007 NCBI chr11:126,235,930...126,268,895
Ensembl chr11:126,262,938...126,269,144
JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA] CTD PMID:11578593 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G SYP synaptophysin multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of SYP mRNA] CTD PMID:21161674 NCBI chr  X:49,187,815...49,200,193
Ensembl chr  X:49,187,815...49,200,218
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased expression of TAP1 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of TAP1 protein] CTD PMID:36423715 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO
EXP
pyrrolidine dithiocarbamic acid affects the reaction [Doxorubicin results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of and results in increased secretion of TGFB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TGFB1 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TGFB1 protein]
CTD PMID:11124598 PMID:12472797 PMID:19272247 PMID:19639047 PMID:26860689 More... NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] CTD PMID:34082047 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA] CTD PMID:12472797 PMID:19272247 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] CTD PMID:15078482 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of TINF2 mRNA CTD PMID:21731707 NCBI chr14:24,239,640...24,242,674
Ensembl chr14:24,238,286...24,242,663
JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases secretion
increases stability
decreases expression
EXP
ISO
[pyrrolidine dithiocarbamic acid co-treated with HLA-B protein alternative form] results in decreased secretion of TNF protein; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Nitric Oxide]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein]
pyrrolidine dithiocarbamic acid results in decreased secretion of TNF protein
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]
pyrrolidine dithiocarbamic acid results in increased stability of TNF mRNA
pyrrolidine dithiocarbamic acid results in decreased expression of TNF mRNA
CTD PMID:8903404 PMID:9756946 PMID:10416616 PMID:10495789 PMID:10653605 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA] CTD PMID:15477007 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TP53 tumor protein p53 multiple interactions
decreases expression
EXP
ISO
[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]; pyrrolidine dithiocarbamic acid results in increased oxidation of and results in increased expression of TP53 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of TP53 protein
CTD PMID:11964141 PMID:16049548 PMID:25559736 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPO thyroid peroxidase multiple interactions
decreases expression
decreases activity
ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of TPO mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] CTD PMID:11108245 NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711
JBrowse link
G TRAF1 TNF receptor associated factor 1 multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA] CTD PMID:15477007 NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173
JBrowse link
G TRIB2 tribbles pseudokinase 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] CTD PMID:15477007 NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734
JBrowse link
G TSHB thyroid stimulating hormone subunit beta multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [TSHB protein results in increased abundance of Hydrogen Peroxide] CTD PMID:11108245 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302
JBrowse link
G TSLP thymic stromal lymphopoietin multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Glupearl 19S results in increased expression of TSLP mRNA] CTD PMID:32493875 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026
JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP multiple interactions EXP [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] CTD PMID:15477007 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP pyrrolidine dithiocarbamic acid results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link
G UBE2L6 ubiquitin conjugating enzyme E2 L6 increases expression
multiple interactions
EXP pyrrolidine dithiocarbamic acid results in increased expression of UBE2L6 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBE2L6 mRNA
CTD PMID:15477007 NCBI chr11:57,551,662...57,567,935
Ensembl chr11:57,551,656...57,568,284
JBrowse link
G UBL4A ubiquitin like 4A multiple interactions EXP [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBL4A mRNA CTD PMID:15477007 NCBI chr  X:154,483,717...154,486,615
Ensembl chr  X:154,483,717...154,486,615
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] CTD PMID:10712386 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G VIM vimentin multiple interactions
decreases expression
EXP
ISO
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of VIM protein]
pyrrolidine dithiocarbamic acid results in decreased expression of VIM protein
CTD PMID:15477007 PMID:30310660 PMID:36722465 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
thiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C2 aldo-keto reductase family 1 member C2 increases activity EXP Thiram results in increased activity of AKR1C2 promoter CTD PMID:21195160 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
JBrowse link
G AMPD3 adenosine monophosphate deaminase 3 increases expression EXP Thiram results in increased expression of AMPD3 mRNA CTD PMID:24211530 NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579
JBrowse link
G ANXA10 annexin A10 increases expression EXP Thiram results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr 4:168,092,537...168,187,736
Ensembl chr 4:168,092,537...168,187,736
JBrowse link
G ARG1 arginase 1 decreases expression EXP Thiram results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ATF3 activating transcription factor 3 increases expression EXP Thiram results in increased expression of ATF3 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G CASP1 caspase 1 affects expression ISO Thiram affects the expression of CASP1 protein CTD PMID:25929180 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CCR2 C-C motif chemokine receptor 2 decreases expression EXP Thiram results in decreased expression of CCR2 mRNA CTD PMID:19371601 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CD86 CD86 molecule increases expression EXP Thiram results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases expression EXP Thiram results in increased expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CREM cAMP responsive element modulator increases expression EXP Thiram results in increased expression of CREM mRNA CTD PMID:19371601 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
increases secretion
multiple interactions
EXP Thiram results in increased expression of CXCL8 mRNA
Thiram results in increased secretion of CXCL8 protein
SB 203580 affects the reaction [Thiram results in increased secretion of CXCL8 protein]
CTD PMID:18494145 PMID:19878716 PMID:21920952 PMID:27965148 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression EXP Thiram results in increased expression of CYP1A1 mRNA; Thiram results in increased expression of CYP1A1 protein CTD PMID:32194361 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases expression EXP Thiram results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases metabolic processing
multiple interactions
ISO CYP2E1 protein results in increased metabolism of Thiram
Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]
CTD PMID:12458634 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP Thiram results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP Thiram results in increased expression of DNAJB4 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
JBrowse link
G FTH1 ferritin heavy chain 1 increases expression EXP Thiram results in increased expression of FTH1 mRNA CTD PMID:24211530 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
JBrowse link
G FTL ferritin light chain increases expression EXP Thiram results in increased expression of FTL mRNA CTD PMID:24211530 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Thiram results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP Thiram results in increased expression of GCLM mRNA CTD PMID:23999411 PMID:24211530 PMID:27965148 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO
EXP
Thiram results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:24211530 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
EXP Dithiothreitol inhibits the reaction [Thiram results in decreased activity of HSD11B2 protein]; Ethylmaleimide promotes the reaction [Thiram results in decreased activity of HSD11B2 protein]; Thiram inhibits the reaction [HSD11B2 protein results in increased oxidation of Dexamethasone] CTD PMID:12901862 PMID:16857225 PMID:22796344 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases activity
multiple interactions
EXP Thiram results in decreased activity of HSD3B1 protein
Dithiothreitol inhibits the reaction [Thiram results in decreased activity of HSD3B1 protein]
CTD PMID:36965607 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP Thiram results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
increases expression
EXP Thiram promotes the reaction [TNF protein results in increased expression of ICAM1 protein]
Thiram results in increased expression of ICAM1 protein
CTD PMID:25752435 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma increases expression ISO Thiram results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL18 interleukin 18 increases expression EXP Thiram results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha increases expression EXP Thiram results in increased expression of IL1A mRNA CTD PMID:33715048 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta increases secretion EXP Thiram results in increased secretion of IL1B protein CTD PMID:33715048 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL4 interleukin 4 increases expression ISO Thiram results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G LEP leptin multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of LEP protein CTD PMID:29321614 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G MT1G metallothionein 1G increases expression EXP Thiram results in increased expression of MT1G mRNA CTD PMID:32870474 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Thiram results in increased expression of MYC mRNA CTD PMID:24211530 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase increases expression EXP Thiram results in increased expression of NAMPT mRNA CTD PMID:19371601 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 decreases expression EXP Thiram results in decreased expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 affects expression ISO Thiram affects the expression of NLRP3 protein CTD PMID:25929180 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NMB neuromedin B multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of NMB mRNA CTD PMID:29321614 NCBI chr15:84,655,132...84,658,199
Ensembl chr15:84,655,129...84,658,563
JBrowse link
G NMBR neuromedin B receptor multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NMBR mRNA CTD PMID:29321614 NCBI chr 6:142,074,484...142,147,122
Ensembl chr 6:142,058,330...142,147,122
JBrowse link
G NPY1R neuropeptide Y receptor Y1 multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NPY1R mRNA CTD PMID:29321614 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Thiram results in increased expression of NQO1 mRNA CTD PMID:24211530 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 multiple interactions EXP Dithiothreitol inhibits the reaction [Thiram inhibits the reaction [Dexamethasone binds to NR3C1 protein]]; Thiram inhibits the reaction [Dexamethasone binds to NR3C1 protein]; Thiram inhibits the reaction [Hydrocortisone binds to NR3C1 protein] CTD PMID:16857225 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G PARK7 Parkinsonism associated deglycase decreases activity EXP Thiram results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 multiple interactions EXP Thiram inhibits the reaction [TNF protein results in decreased expression of PECAM1 protein] CTD PMID:25752435 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PRKCA protein kinase C alpha decreases activity EXP Thiram results in decreased activity of PRKCA protein CTD PMID:15998240 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PRKCB protein kinase C beta decreases activity EXP Thiram results in decreased activity of PRKCB protein CTD PMID:15998240 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCD protein kinase C delta increases activity EXP Thiram results in increased activity of PRKCD protein CTD PMID:15998240 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PRKCE protein kinase C epsilon decreases activity EXP Thiram results in decreased activity of PRKCE protein CTD PMID:15998240 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G PRKCG protein kinase C gamma decreases activity EXP Thiram results in decreased activity of PRKCG protein CTD PMID:15998240 NCBI chr19:53,881,094...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression EXP Thiram results in increased expression of PTGS2 mRNA CTD PMID:19371601 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G S100P S100 calcium binding protein P increases expression EXP Thiram results in increased expression of S100P protein CTD PMID:32194361 NCBI chr 4:6,693,878...6,697,170
Ensembl chr 4:6,693,878...6,697,170
JBrowse link
G SEL1L3 SEL1L family member 3 increases expression EXP Thiram results in increased expression of SEL1L3 mRNA CTD PMID:24211530 NCBI chr 4:25,713,964...25,863,566
Ensembl chr 4:25,747,433...25,863,760
JBrowse link
G SFTPA1 surfactant protein A1 multiple interactions EXP Thiram inhibits the reaction [Dexamethasone results in decreased expression of SFTPA1 mRNA] CTD PMID:16857225 NCBI chr10:79,610,939...79,615,455
Ensembl chr10:79,610,939...79,615,455
JBrowse link
G SFTPB surfactant protein B multiple interactions EXP Thiram inhibits the reaction [Dexamethasone results in increased expression of SFTPB mRNA] CTD PMID:16857225 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741
JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP Thiram results in increased expression of SLC7A11 mRNA CTD PMID:24211530 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SQSTM1 sequestosome 1 increases expression EXP Thiram results in increased expression of SQSTM1 mRNA CTD PMID:24211530 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SYNE2 spectrin repeat containing nuclear envelope protein 2 decreases expression EXP Thiram results in decreased expression of SYNE2 mRNA CTD PMID:24211530 NCBI chr14:63,761,596...64,226,449
Ensembl chr14:63,761,899...64,226,433
JBrowse link
G TGFB1 transforming growth factor beta 1 decreases activity EXP Thiram results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
EXP Thiram results in increased expression of TNF mRNA
Thiram inhibits the reaction [TNF protein results in decreased expression of PECAM1 protein]; Thiram inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Thiram promotes the reaction [TNF protein results in increased expression of ICAM1 protein]
CTD PMID:20385217 PMID:25752435 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNNT2 troponin T2, cardiac type decreases expression EXP Thiram results in decreased expression of TNNT2 mRNA CTD PMID:24211530 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TRIM16L tripartite motif containing 16 like (pseudogene) increases expression EXP Thiram results in increased expression of TRIM16L mRNA CTD PMID:24211530 NCBI chr17:18,697,998...18,736,112
Ensembl chr17:18,722,237...18,735,460
Ensembl chr17:18,722,237...18,735,460
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression ISO
EXP
Thiram results in increased expression of TXNRD1 mRNA CTD PMID:23445166 PMID:24211530 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions EXP Thiram results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP Thiram inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:25752435 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
ziram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA CTD PMID:32745781 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA CTD PMID:32736067 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Ziram results in decreased phosphorylation of AKT1 protein CTD PMID:30422632 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G AMH anti-Mullerian hormone decreases expression
increases expression
ISO Ziram results in decreased expression of AMH mRNA; Ziram results in decreased expression of AMH protein
Ziram results in increased expression of AMH mRNA
CTD PMID:29627606 PMID:30422632 NCBI chr19:2,249,323...2,252,073
Ensembl chr19:2,249,309...2,252,073
JBrowse link
G APLN apelin increases expression EXP Ziram results in increased expression of APLN mRNA CTD PMID:32870474 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression ISO Ziram results in increased expression of BAX protein CTD PMID:28973382 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression ISO Ziram results in decreased expression of BCL2 protein CTD PMID:28973382 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G CASP1 caspase 1 multiple interactions ISO Acetylcysteine inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Dithiothreitol inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Edetic Acid inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Mercaptoethanol inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]; Ziram results in decreased expression of and results in increased degradation of CASP1 protein CTD PMID:25929180 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 increases activity EXP Ziram results in increased activity of CASP3 protein CTD PMID:20842346 PMID:22159898 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 increases activity EXP Ziram results in increased activity of CASP8 protein CTD PMID:22159898 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 increases activity EXP Ziram results in increased activity of CASP9 protein CTD PMID:22159898 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase increases expression EXP Ziram results in increased expression of CAT mRNA CTD PMID:32712770 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases secretion
multiple interactions
EXP Ziram results in decreased secretion of CCL2 protein
Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
CTD PMID:32712770 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCND3 cyclin D3 decreases expression ISO Ziram results in decreased expression of CCND3 mRNA CTD PMID:28973382 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
JBrowse link
G CCR2 C-C motif chemokine receptor 2 decreases expression
increases expression
EXP Ziram results in decreased expression of CCR2 protein
Ziram results in increased expression of CCR2 mRNA
CTD PMID:32712770 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CD163 CD163 molecule decreases expression EXP Ziram results in decreased expression of CD163 mRNA; Ziram results in decreased expression of CD163 protein CTD PMID:32712770 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893
JBrowse link
G CD209 CD209 molecule increases expression EXP Ziram results in increased expression of CD209 mRNA; Ziram results in increased expression of CD209 protein CTD PMID:32712770 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564
JBrowse link
G CD36 CD36 molecule (CD36 blood group) decreases expression
multiple interactions
EXP
ISO
Ziram results in decreased expression of CD36 mRNA; Ziram results in decreased expression of CD36 protein
[Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA
CTD PMID:32712770 PMID:32736067 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CLEC7A C-type lectin domain containing 7A decreases expression EXP Ziram results in decreased expression of CLEC7A protein CTD PMID:32712770 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258
JBrowse link
G CNN2 calponin 2 increases expression EXP Ziram results in increased expression of CNN2 mRNA CTD PMID:32870474 NCBI chr19:1,026,608...1,039,065
Ensembl chr19:1,026,586...1,039,068
JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA CTD PMID:32736067 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G CYCS cytochrome c, somatic affects localization EXP Ziram affects the localization of CYCS protein CTD PMID:20842346 PMID:22159898 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 decreases activity
affects expression
decreases expression
ISO Ziram results in decreased activity of CYP11A1 protein
Ziram affects the expression of CYP11A1 mRNA; Ziram affects the expression of CYP11A1 protein
Ziram results in decreased expression of CYP11A1 mRNA; Ziram results in decreased expression of CYP11A1 protein
CTD PMID:28973382 PMID:29627606 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 decreases expression
affects expression
decreases activity
ISO Ziram results in decreased expression of CYP17A1 mRNA; Ziram results in decreased expression of CYP17A1 protein
Ziram affects the expression of CYP17A1 mRNA; Ziram affects the expression of CYP17A1 protein
Ziram results in decreased activity of CYP17A1 protein
CTD PMID:28973382 PMID:29627606 PMID:30422632 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA CTD PMID:32736067 PMID:32745781 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA CTD PMID:32745781 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP Ziram results in increased expression of DDIT3 mRNA CTD PMID:32870474 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DHH desert hedgehog signaling molecule decreases expression ISO Ziram results in decreased expression of DHH mRNA; Ziram results in decreased expression of DHH protein CTD PMID:29627606 NCBI chr12:49,086,656...49,094,801
Ensembl chr12:49,086,656...49,094,801
JBrowse link
G DIO1 iodothyronine deiodinase 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA CTD PMID:32745781 NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
JBrowse link
G ECI1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA CTD PMID:32736067 NCBI chr16:2,239,402...2,251,587
Ensembl chr16:2,239,402...2,252,300
JBrowse link
G ELFN2 extracellular leucine rich repeat and fibronectin type III domain containing 2 increases expression EXP Ziram results in increased expression of ELFN2 mRNA CTD PMID:32870474 NCBI chr22:37,340,644...37,427,479
Ensembl chr22:37,367,960...37,427,479
Ensembl chr22:37,367,960...37,427,479
JBrowse link
G FCGR3A Fc gamma receptor IIIa decreases expression EXP Ziram results in decreased expression of FCGR3A protein CTD PMID:18670896 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
JBrowse link
G FCGR3B Fc gamma receptor IIIb increases expression EXP Ziram results in increased expression of FCGR3B mRNA CTD PMID:32712770 NCBI chr 1:161,623,196...161,631,963
Ensembl chr 1:161,623,196...161,631,963
JBrowse link
G FIBIN fin bud initiation factor homolog increases expression EXP Ziram results in increased expression of FIBIN mRNA CTD PMID:32870474 NCBI chr11:26,994,112...26,997,087
Ensembl chr11:26,994,112...26,997,087
JBrowse link
G FSHB follicle stimulating hormone subunit beta decreases expression ISO Ziram results in decreased expression of FSHB mRNA; Ziram results in decreased expression of FSHB protein CTD PMID:28973382 PMID:30422632 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
JBrowse link
G FSHR follicle stimulating hormone receptor decreases expression ISO Ziram results in decreased expression of FSHR mRNA; Ziram results in decreased expression of FSHR protein CTD PMID:29627606 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein CTD PMID:32736067 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GNLY granulysin decreases expression EXP Ziram results in decreased expression of GNLY protein CTD PMID:22038140 NCBI chr 2:85,694,358...85,698,852
Ensembl chr 2:85,685,175...85,698,852
JBrowse link
G GZMA granzyme A decreases expression EXP Ziram results in decreased expression of GZMA protein CTD PMID:22038140 NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
JBrowse link
G GZMB granzyme B decreases expression EXP Ziram results in decreased expression of GZMB protein CTD PMID:21859362 PMID:22038140 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
JBrowse link
G GZMK granzyme K decreases expression EXP Ziram results in decreased expression of GZMK protein CTD PMID:22038140 NCBI chr 5:55,024,256...55,034,570
Ensembl chr 5:55,024,256...55,034,570
JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA CTD PMID:32745781 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression
EXP Trientine inhibits the reaction [Ziram results in increased expression of HMOX1 protein]
Ziram results in increased expression of HMOX1 mRNA; Ziram results in increased expression of HMOX1 protein
CTD PMID:25714994 PMID:32712770 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions
decreases expression
decreases activity
ISO Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone]; Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP]; Ziram inhibits the reaction [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone]
Ziram results in decreased expression of HSD11B1 mRNA; Ziram results in decreased expression of HSD11B1 protein
Ziram results in decreased activity of HSD11B1 protein
CTD PMID:26859423 PMID:28973382 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
EXP
ISO
Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Hydrocortisone] which results in increased chemical synthesis of Cortisone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Hydrocortisone]; Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD]
Dithiothreitol inhibits the reaction [Ziram results in decreased activity of HSD11B2 protein]; Ziram inhibits the reaction [[HSD11B2 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased oxidation of Corticosterone]; Ziram inhibits the reaction [HSD11B2 protein results in increased reduction of NAD]
CTD PMID:26859423 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 decreases activity
decreases expression
ISO Ziram results in decreased activity of HSD17B3 protein
Ziram results in decreased expression of HSD17B3 mRNA; Ziram results in decreased expression of HSD17B3 protein
CTD PMID:28973382 PMID:29627606 PMID:30422632 NCBI chr 9:96,235,306...96,302,176
Ensembl chr 9:96,235,306...96,302,176
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases activity
decreases expression
ISO Ziram results in decreased activity of HSD3B1 protein
Ziram results in decreased expression of HSD3B1 mRNA; Ziram results in decreased expression of HSD3B1 protein
CTD PMID:28973382 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
JBrowse link
G IFNB1 interferon beta 1 multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942
JBrowse link
G IFNG interferon gamma increases expression ISO Ziram results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO
EXP
Ziram inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:25929180 PMID:32712770 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL4 interleukin 4 increases expression ISO Ziram results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 multiple interactions EXP Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:32712770 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of INS1 protein CTD PMID:32745781 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
JBrowse link
G INSL3 insulin like 3 decreases expression ISO Ziram results in decreased expression of INSL3 mRNA; Ziram results in decreased expression of INSL3 protein CTD PMID:29627606 NCBI chr19:17,816,512...17,821,519
Ensembl chr19:17,816,512...17,821,574
JBrowse link
G ITGAM integrin subunit alpha M increases expression EXP Ziram results in increased expression of ITGAM mRNA; Ziram results in increased expression of ITGAM protein CTD PMID:32712770 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G LEP leptin multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of LEP protein CTD PMID:29321614 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of LEPR mRNA CTD PMID:29321614 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor decreases expression
affects expression
ISO Ziram results in decreased expression of LHCGR mRNA; Ziram results in decreased expression of LHCGR protein
Ziram affects the expression of LHCGR mRNA; Ziram affects the expression of LHCGR protein
CTD PMID:28973382 PMID:29627606 PMID:30422632 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases activity EXP Ziram results in increased activity of MAPK1 protein CTD PMID:21859362 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases activity EXP Ziram results in increased activity of MAPK3 protein CTD PMID:21859362 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MRC1 mannose receptor C-type 1 decreases expression EXP Ziram results in decreased expression of MRC1 protein CTD PMID:32712770 NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164
JBrowse link
G MT1E metallothionein 1E increases expression EXP Ziram results in increased expression of MT1E mRNA CTD PMID:32870474 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112
JBrowse link
G MT1F metallothionein 1F increases expression EXP Ziram results in increased expression of MT1F mRNA CTD PMID:32870474 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
JBrowse link
G MT1G metallothionein 1G increases expression EXP Ziram results in increased expression of MT1G mRNA CTD PMID:32870474 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MT1H metallothionein 1H increases expression EXP Ziram results in increased expression of MT1H mRNA CTD PMID:32870474 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
JBrowse link
G MT1L metallothionein 1L (pseudogene) increases expression EXP Ziram results in increased expression of MT1L mRNA CTD PMID:32870474 NCBI chr16:56,617,461...56,618,818
Ensembl chr16:56,617,563...56,618,680
JBrowse link
G MT1X metallothionein 1X increases expression EXP Ziram results in increased expression of MT1X mRNA CTD PMID:32870474 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G MT2A metallothionein 2A increases expression EXP Ziram results in increased expression of MT2A mRNA CTD PMID:32870474 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
JBrowse link
G MT4 metallothionein 4 decreases expression EXP Ziram results in decreased expression of MT4 mRNA CTD PMID:32870474 NCBI chr16:56,565,073...56,568,957
Ensembl chr16:56,565,073...56,568,957
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 affects expression EXP Ziram affects the expression of NFE2L2 mRNA CTD PMID:32712770 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO Ziram inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 decreases expression ISO Ziram results in decreased expression of NLRP3 protein CTD PMID:25929180 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G NMB neuromedin B multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in decreased expression of NMB mRNA CTD PMID:29321614 NCBI chr15:84,655,132...84,658,199
Ensembl chr15:84,655,129...84,658,563
JBrowse link
G NMBR neuromedin B receptor multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NMBR mRNA CTD PMID:29321614 NCBI chr 6:142,074,484...142,147,122
Ensembl chr 6:142,058,330...142,147,122
JBrowse link
G NPY1R neuropeptide Y receptor Y1 multiple interactions ISO [2-amino-3-chloro-1,4-naphthoquinone co-treated with Ziram co-treated with cyromazine co-treated with 2-methyl-4-chlorophenoxy gamma-butyric acid co-treated with pirimicarb co-treated with Thiram] results in increased expression of NPY1R mRNA CTD PMID:29321614 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions ISO NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] CTD PMID:29950287 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 decreases expression
affects expression
ISO Ziram results in decreased expression of NR5A1 mRNA; Ziram results in decreased expression of NR5A1 protein
Ziram affects the expression of NR5A1 mRNA; Ziram affects the expression of NR5A1 protein
CTD PMID:28973382 PMID:29627606 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420
JBrowse link
G PARK7 Parkinsonism associated deglycase decreases activity EXP Ziram results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PDGFRB platelet derived growth factor receptor beta multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein CTD PMID:32736067 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 affects expression EXP Ziram affects the expression of PDK4 mRNA CTD PMID:32870474 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma affects expression EXP Ziram affects the expression of PPARG mRNA CTD PMID:32712770 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha decreases expression ISO Ziram results in decreased expression of PPARGC1A protein CTD PMID:30422632 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRF1 perforin 1 decreases expression EXP Ziram results in decreased expression of PRF1 protein CTD PMID:21859362 PMID:22038140 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759
JBrowse link
G PRSS56 serine protease 56 increases expression EXP Ziram results in increased expression of PRSS56 mRNA CTD PMID:32870474 NCBI chr 2:232,520,388...232,525,716
Ensembl chr 2:232,520,388...232,525,716
JBrowse link
G SCARB1 scavenger receptor class B member 1 decreases expression
affects expression
ISO Ziram results in decreased expression of SCARB1 mRNA; Ziram results in decreased expression of SCARB1 protein
Ziram affects the expression of SCARB1 mRNA; Ziram affects the expression of SCARB1 protein
CTD PMID:28973382 PMID:29627606 PMID:30422632 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SERPINE1 serpin family E member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SIRT1 sirtuin 1 decreases expression ISO Ziram results in decreased expression of SIRT1 protein CTD PMID:30422632 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC16A2 solute carrier family 16 member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA CTD PMID:32745781 NCBI chr  X:74,421,493...74,533,916
Ensembl chr  X:74,421,493...74,533,917
JBrowse link
G SLC30A1 solute carrier family 30 member 1 increases expression EXP Ziram results in increased expression of SLC30A1 mRNA CTD PMID:32870474 NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
JBrowse link
G SLC30A2 solute carrier family 30 member 2 increases expression EXP Ziram results in increased expression of SLC30A2 mRNA CTD PMID:32870474 NCBI chr 1:26,037,252...26,046,118
Ensembl chr 1:26,037,252...26,046,118
JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP Ziram results in increased expression of SLC7A11 mRNA CTD PMID:32870474 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SLC8A3 solute carrier family 8 member A3 increases response to substance
decreases response to substance
ISO SLC8A3 results in increased susceptibility to Ziram
SLC8A3 gene mutant form results in decreased susceptibility to Ziram
CTD PMID:25284465 NCBI chr14:70,044,215...70,189,405
Ensembl chr14:70,044,215...70,189,480
JBrowse link
G SMAD3 SMAD family member 3 multiple interactions EXP Ziram inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:31652400 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SNCA synuclein alpha increases expression ISO Ziram results in increased expression of SNCA protein CTD PMID:18818210 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SOD2 superoxide dismutase 2 increases expression EXP Ziram results in increased expression of SOD2 mRNA CTD PMID:32712770 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOX9 SRY-box transcription factor 9 decreases expression ISO Ziram results in decreased expression of SOX9 mRNA; Ziram results in decreased expression of SOX9 protein CTD PMID:29627606 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 decreases expression
decreases activity
ISO Ziram results in decreased expression of SRD5A1 mRNA
Ziram results in decreased activity of SRD5A1 protein
CTD PMID:28707553 PMID:30422632 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,290...6,676,539
JBrowse link
G STAR steroidogenic acute regulatory protein decreases expression
affects expression
ISO Ziram results in decreased expression of STAR mRNA; Ziram results in decreased expression of STAR protein
Ziram affects the expression of STAR mRNA; Ziram affects the expression of STAR protein
CTD PMID:28973382 PMID:29627606 PMID:30422632 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G SULT1B1 sulfotransferase family 1B member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA CTD PMID:32745781 NCBI chr 4:69,721,167...69,760,620
Ensembl chr 4:69,721,167...69,787,961
JBrowse link
G TGFB1 transforming growth factor beta 1 decreases activity
multiple interactions
EXP Ziram results in decreased activity of TGFB1 protein
Ziram inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD PMID:31652400 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G THRSP thyroid hormone responsive multiple interactions ISO [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] CTD PMID:32745781 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP Ziram inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:16112155 PMID:32712770 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TPO thyroid peroxidase decreases activity EXP Ziram results in decreased activity of TPO protein CTD PMID:9248629 NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711
JBrowse link
G TSPO translocator protein decreases expression ISO Ziram results in decreased expression of TSPO mRNA CTD PMID:28973382 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242
JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 decreases activity
multiple interactions
EXP Ziram results in decreased activity of UBA1 protein
Trientine inhibits the reaction [Ziram results in decreased activity of and results in decreased ubiquitination of UBA1 protein]; Ziram results in decreased activity of and results in decreased ubiquitination of UBA1 protein
CTD PMID:18818210 PMID:25714994 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    chemical entity 26020
      atom 26016
        nonmetal atom 25505
          sulfur atom 20129
            sulfur molecular entity 20129
              organosulfur compound 19543
                dithiocarbamic acids 426
                  carbamodithioic acid 0
                  dibutyldithiocarbamic acid + 0
                  diethyldithiocarbamic acid + 53
                  dimethyldithiocarbamic acid + 149
                  ethylenebis(dithiocarbamic acid) 0
                  metam 79
                  propylene 1,2-bis(dithiocarbamic acid) 0
                  pyrrolidine dithiocarbamate 244
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            heteroorganic entity 24773
                              organochalcogen compound 24384
                                organosulfur compound 19543
                                  thiocarbonyl compound 7812
                                    dithiocarbamic acids 426
                                      carbamodithioic acid 0
                                      dibutyldithiocarbamic acid + 0
                                      diethyldithiocarbamic acid + 53
                                      dimethyldithiocarbamic acid + 149
                                      ethylenebis(dithiocarbamic acid) 0
                                      metam 79
                                      propylene 1,2-bis(dithiocarbamic acid) 0
                                      pyrrolidine dithiocarbamate 244
paths to the root