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ONTOLOGY REPORT - ANNOTATIONS


Term:cantharidic acid
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Accession:CHEBI:78695 term browser browse the term
Definition:A monoterpenoid with an epoxy-bridged bicyclic dicarboxylic acid structure, which acts as an inhibitor of protein phosphatases 1 and 2A.
Synonyms:exact_synonym: (1R,2S,3R,4S)-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
 related_synonym: Formula=C10H14O5;   InChI=1S/C10H14O5/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)/t5-,6+,9+,10-;   InChIKey=NMTNUQBORQILRK-XCVPVQRUSA-N;   SMILES=C[C@@]1([C@@H]2CC[C@@H](O2)[C@@]1(C)C(O)=O)C(O)=O
 xref: CAS:28874-45-5 "ChemIDplus"
 xref_mesh: MESH:C000626960
 xref: PMID:10403630 "Europe PMC";   PMID:10900240 "Europe PMC";   PMID:22210093 "Europe PMC";   PMID:22337773 "Europe PMC";   PMID:2955551 "Europe PMC";   Patent:WO2011056222;   Reaxys:17311 "Reaxys";   Wikipedia:Cantharidic_acid


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cantharidic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        aetiopathogenetic role 18752
          hepatotoxic agent 14276
            cantharidic acid 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic anhydride 1938
                                        cyclic dicarboxylic anhydride 1934
                                          cantharidin 31
                                            cantharidic acid 8
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