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ONTOLOGY REPORT - ANNOTATIONS


Term:oxymetholone
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Accession:CHEBI:7864 term browser browse the term
Definition:A 3-oxo-5alpha- steroid that is 4,5alpha-dihydrotestosterone which is substituted by a hydroxymethylidene group at position 2 and by a methyl group at the 17alpha position. A synthetic androgen, it was mainly used for the treatment of anaemias until being replaced by treatments with fewer side effects.
Synonyms:exact_synonym: 17beta-hydroxy-2-(hydroxymethylidene)-17-methyl-5alpha-androstan-3-one
 related_synonym: (5alpha,17beta)-17-hydroxy-2-(hydroxymethylidene)-17-methylandrostan-3-one;   17alpha-methyl-2-hydroxymethylene-17-hydroxy-5alpha-androstan-3-one;   17beta-hydroxy-2-(hydroxymethylene)-17-methyl-5alpha-androstan-3-one;   2-hydroxymethylene-17alpha-methyl-17beta-hydroxy-5alpha-androstan-3-one;   2-hydroxymethylene-17alpha-methyl-5alpha-androstan-17beta-ol-3-one;   2-hydroxymethylene-17alpha-methyldihydrotestosterone;   4,5alpha-dihydro-2-hydroxymethylene-17alpha-methyltestosterone;   Adroyd;   Anadrol-50;   Anapolon;   Formula=C21H32O3;   InChI=1S/C21H32O3/c1-19-11-13(12-22)18(23)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,22,24H,4-11H2,1-3H3/t14-,15+,16-,17-,19-,20-,21-/m0/s1;   InChIKey=ICMWWNHDUZJFDW-IYRCEVNGSA-N;   Nastenon;   Pardroyd;   Plenastril;   Protanabol;   SMILES=C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)C(C[C@]4(C)[C@H]3CC[C@]12C)=CO;   Synasteron;   oximetolona;   oxymetholonum
 xref: CAS:434-07-1 "ChemIDplus";   CAS:434-07-1 "KEGG COMPOUND";   CAS:434-07-1 "NIST Chemistry WebBook";   KEGG:C07393;   KEGG:D00490
 xref_mesh: MESH:D010110
 xref: PMID:11071398 "Europe PMC";   PMID:1125426 "Europe PMC";   PMID:11440282 "Europe PMC";   PMID:21860526 "Europe PMC";   Patent:DE1070632;   Reaxys:2623806 "Reaxys";   Wikipedia:Oxymetholone


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oxymetholone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 JBrowse link 19 37,476,083 37,481,326 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Il7 interleukin 7 JBrowse link 2 96,427,884 96,474,979 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tpo thyroid peroxidase JBrowse link 6 49,020,918 49,089,855 RGD:6480464
stanozolol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        anti-anaemic agent 10
          oxymetholone 10
            stanozolol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      ketone 15789
                                        oxo steroid 9257
                                          3-oxo steroid 8780
                                            3-oxo-5alpha-steroid 981
                                              oxymetholone 10
                                                stanozolol 2
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