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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chroman-6-ol
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Accession:CHEBI:78631 term browser browse the term
Definition:A chromanol that is chromane in which the hydrogen at position 6 is replaced by a hydroxy group.
Synonyms:exact_synonym: 3,4-dihydro-2H-chromen-6-ol
 related_synonym: 3,4-dihydrobenzopyran-6-ol;   Formula=C9H10O2;   InChI=1S/C9H10O2/c10-8-3-4-9-7(6-8)2-1-5-11-9/h3-4,6,10H,1-2,5H2;   InChIKey=GZCJJOLJSBCUNR-UHFFFAOYSA-N;   SMILES=Oc1ccc2OCCCc2c1
 xref: Reaxys:1283166


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(+)-alpha-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein] CTD PMID:24448832 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD1 mRNA] CTD PMID:29065513 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD3 mRNA] CTD PMID:29065513 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein] CTD PMID:10656290 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein] CTD PMID:19464315 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP alpha-Tocopherol results in increased expression of ACVRL1 mRNA CTD PMID:16908007 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Agt angiotensinogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein]; alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP alpha-Tocopherol results in increased expression of AKR1B1 mRNA CTD PMID:16908007 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of AKT1 protein]
CTD PMID:19351882, PMID:22343715 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin multiple interactions EXP alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]] CTD PMID:17429802 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ano6 anoctamin 6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of ANO6 mRNA] CTD PMID:27886375 NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA]
alpha-Tocopherol results in decreased expression of APEX2 mRNA
CTD PMID:26332274 NCBI chr  X:23,146,085...23,166,676
Ensembl chr  X:23,146,085...23,166,675
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
decreases activity
ISO
EXP
alpha-Tocopherol results in decreased expression of APOA1 mRNA; alpha-Tocopherol results in decreased expression of APOA1 protein
alpha-Tocopherol results in decreased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B multiple interactions ISO alpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper] CTD PMID:11368321 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] CTD PMID:12684028 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of ATF2 protein] CTD PMID:14645110 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP alpha-Tocopherol results in increased expression of BAD mRNA CTD PMID:26332274 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in increased expression of BAX protein]
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein]
alpha-Tocopherol results in increased expression of BAX mRNA
CTD PMID:11805214, PMID:26332274, PMID:32134168 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Endosulfan results in decreased activity of BCHE protein] CTD PMID:24299906 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; TNFRSF10B mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]
alpha-Tocopherol analog results in decreased expression of BCL2 mRNA; alpha-Tocopherol analog results in decreased expression of BCL2 protein
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of BCL2 protein]
CTD PMID:11805214, PMID:16005924, PMID:16135673, PMID:20686688 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP alpha-Tocopherol results in decreased expression of BCL2L1 protein CTD PMID:18942769 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased expression of BDNF protein] CTD PMID:30776390 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Canx calnexin affects localization
increases expression
EXP alpha-Tocopherol affects the localization of CANX protein
alpha-Tocopherol results in increased expression of CANX mRNA; alpha-Tocopherol results in increased expression of CANX protein
CTD PMID:16908007 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
ISO
EXP
[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein; [alpha-Tocopherol co-treated with Tretinoin] results in increased activity of CASP3 protein; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Acetaldehyde results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP3 protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased cleavage of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein]
alpha-Tocopherol results in decreased activity of CASP3 protein
CTD PMID:12450566, PMID:14599462, PMID:14722101, PMID:15095415, PMID:17618090, PMID:17874176, PMID:17936189, PMID:21869839, PMID:22389237, PMID:23042730, PMID:29065513, PMID:29129777, PMID:30776390, PMID:31712109, PMID:32134168 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]] CTD PMID:23042730, PMID:29129777 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases cleavage ISO alpha-Tocopherol analog results in increased cleavage of CASP8 protein CTD PMID:20686688 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO alpha-Tocopherol analog results in increased cleavage of CASP9 protein
alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]
alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP9 protein
CTD PMID:20686688, PMID:21869839, PMID:31712109 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
increases activity
increases expression
EXP
ISO
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [Copper Sulfate results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
alpha-Tocopherol results in increased activity of CAT protein
alpha-Tocopherol results in increased expression of CAT protein
alpha-Tocopherol results in increased expression of CAT mRNA; alpha-Tocopherol results in increased expression of CAT protein
CTD PMID:9306888, PMID:16979807, PMID:18547560, PMID:19083475, PMID:19464315, PMID:19941068, PMID:20194575, PMID:21322096, PMID:22732938, PMID:27823922, PMID:30057697, PMID:31022331 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA] CTD PMID:27257344 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD PMID:19735175, PMID:24333275, PMID:26332274 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA] CTD PMID:26332274 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA] CTD PMID:26332274 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd36 CD36 molecule affects expression
multiple interactions
EXP alpha-Tocopherol affects the expression of CD36 mRNA
alpha-Tocopherol inhibits the reaction [[troglitazone co-treated with Ethanol] results in increased expression of CD36 protein]
CTD PMID:16407258 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]
alpha-Tocopherol results in decreased expression of CDKN1A mRNA
CTD PMID:26332274 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO alpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein] CTD PMID:20363832 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] CTD PMID:25891525 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of CLCN3 mRNA] CTD PMID:27886375 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Cldn2 claudin 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Potassium Dichromate affects the localization of CLDN2 protein] CTD PMID:19766176 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CPT1A mRNA]; alpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA]
alpha-Tocopherol results in increased expression of CPT1A mRNA
CTD PMID:17936189 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 mRNA; [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 protein CTD PMID:15225641 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased phosphorylation of CREB1 protein] CTD PMID:30776390 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crp C-reactive protein multiple interactions ISO [alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of CRP protein CTD PMID:18191645 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cryaa crystallin, alpha A increases expression EXP alpha-Tocopherol results in increased expression of CRYAA mRNA CTD PMID:16908007 NCBI chr20:10,438,444...10,442,189
Ensembl chr20:10,438,444...10,442,187
JBrowse link
G Ctsd cathepsin D increases expression EXP alpha-Tocopherol results in increased expression of CTSD protein CTD PMID:18942769 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA] CTD PMID:24333275 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA] CTD PMID:24333275 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP alpha-Tocopherol results in increased expression of CYP1A1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA]; alpha-Tocopherol results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:15665910, PMID:22389237 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
multiple interactions
EXP
ISO
alpha-Tocopherol results in increased activity of CYP1A2 protein
alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]
CTD PMID:15665910, PMID:26102010 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO alpha-Tocopherol results in decreased expression of CYP2B10 mRNA CTD PMID:26102010 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression ISO alpha-Tocopherol results in decreased expression of CYP2B9 mRNA CTD PMID:26102010 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein] CTD PMID:26102010 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
multiple interactions
EXP
ISO
alpha-Tocopherol results in increased expression of CYP2E1 mRNA
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]
CTD PMID:26332274, PMID:27919644, PMID:28062356 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA] CTD PMID:27919644 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions
ISO alpha-Tocopherol results in increased expression of CYP3A13 mRNA; alpha-Tocopherol results in increased expression of CYP3A13 protein
alpha-Tocopherol inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]
CTD PMID:26102010, PMID:31102695 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Cadmium Chloride results in increased expression of DDIT3 mRNA]
alpha-Tocopherol analog results in increased expression of DDIT3 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased expression of DDIT3 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased expression of DDIT3 protein]
CTD PMID:20459685, PMID:20686688 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects localization ISO alpha-Tocopherol affects the localization of DIABLO protein CTD PMID:15582575 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation
multiple interactions
ISO alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of EIF2A protein]
CTD PMID:20686688 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Faslg Fas ligand increases expression EXP alpha-Tocopherol results in increased expression of FASLG mRNA CTD PMID:26332274 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbl fibrillarin decreases expression EXP alpha-Tocopherol deficiency results in decreased expression of FBL protein CTD PMID:15247049 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression EXP alpha-Tocopherol results in increased expression of FMO1 mRNA CTD PMID:16908007 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein] CTD PMID:9225831 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of FYN protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of FYN protein] CTD PMID:14572611 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP alpha-Tocopherol results in increased expression of GADD45A mRNA CTD PMID:26332274 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLC mRNA CTD PMID:24530478 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP
ISO
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA]
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA
CTD PMID:22389237, PMID:24530478 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP alpha-Tocopherol results in increased expression of GFAP protein CTD PMID:18942769 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP alpha-Tocopherol inhibits the reaction [beryllium nitrate results in increased activity of GPT protein] CTD PMID:17429802 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Sodium Selenite results in increased expression of GPX4 mRNA] CTD PMID:14642406 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein] CTD PMID:16979807 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP alpha-Tocopherol results in increased expression of GSTT1 protein CTD PMID:9855024 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gusb glucuronidase, beta multiple interactions ISO alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in decreased uptake of GUSB protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of GUSB protein] CTD PMID:19135433 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Hal histidine ammonia lyase increases expression EXP alpha-Tocopherol results in increased expression of HAL mRNA CTD PMID:16908007 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:19595682, PMID:21535577 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
multiple interactions
ISO
EXP
alpha-Tocopherol affects the expression of HMOX1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein]; alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]
alpha-Tocopherol inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]
CTD PMID:8743975, PMID:12180188, PMID:22053912, PMID:22389237 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin affects activity
multiple interactions
ISO alpha-Tocopherol affects the activity of HP protein polymorphism
Ascorbic Acid inhibits the reaction [alpha-Tocopherol affects the activity of HP protein polymorphism]
CTD PMID:19769483 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD17B3 mRNA] CTD PMID:32134168 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of HSD3B2 mRNA] CTD PMID:32134168 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP alpha-Tocopherol results in increased expression of HSPA1B mRNA CTD PMID:16908007 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 protein] CTD PMID:22313677, PMID:25551565 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma multiple interactions EXP [alpha-Tocopherol co-treated with Lipopolysaccharides] results in increased expression of IFNG mRNA; alpha-Tocopherol results in decreased susceptibility to [IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] CTD PMID:16307444, PMID:24333275 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; alpha-Tocopherol promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
[alpha-Tocopherol co-treated with Lipopolysaccharides] results in increased expression of IL10 mRNA
CTD PMID:24333275, PMID:25551565 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein] CTD PMID:15025948 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of IL1B protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of IL1B protein]; alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of IL1B mRNA]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of IL1B mRNA]
CTD PMID:19135433, PMID:19735175, PMID:26332274, PMID:31712109 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]
alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of IL6 protein]
alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:15630180, PMID:24296301, PMID:32134168 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of JUN protein]
alpha-Tocopherol results in increased expression of JUN mRNA; alpha-Tocopherol results in increased expression of JUN protein
CTD PMID:14645110, PMID:19000923, PMID:20025956 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein] CTD PMID:12531891 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Cadmium results in decreased activity of LCAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:19595682, PMID:21535577 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LCK protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LCK protein] CTD PMID:14572611 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:21322096 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:21322096 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO alpha-Tocopherol inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LYN protein]; alpha-Tocopherol inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LYN protein] CTD PMID:14572611 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
affects activity
ISO
EXP
alpha-Tocopherol inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK1 protein]
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK1 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of MAPK1 protein]
[alpha-Tocopherol affects the activity of MAPK1 protein] which results in decreased susceptibility to Potassium Dichromate
CTD PMID:17011908, PMID:19766176, PMID:30776390 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein] CTD PMID:12684028, PMID:14645110 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
affects activity
ISO
EXP
alpha-Tocopherol inhibits the reaction [Tamoxifen results in decreased phosphorylation of MAPK3 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK3 protein]
[Nimodipine co-treated with alpha-Tocopherol] inhibits the reaction [Dibutyl Phthalate results in increased expression of and results in increased phosphorylation of MAPK3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of MAPK3 protein]
[alpha-Tocopherol affects the activity of MAPK3 protein] which results in decreased susceptibility to Potassium Dichromate
CTD PMID:14645110, PMID:17011908, PMID:19766176, PMID:30776390 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein] CTD PMID:12684028, PMID:14645110, PMID:20686688 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK9 protein]
CTD PMID:20686688 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mb myoglobin multiple interactions EXP alpha-Tocopherol inhibits the reaction [MB modified form results in decreased secretion of very low density lipoprotein triglyceride] CTD PMID:17478120 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mbp myelin basic protein multiple interactions ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased expression of MBP protein] CTD PMID:14645110 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase increases expression EXP alpha-Tocopherol results in increased expression of MGAT3 mRNA CTD PMID:16908007 NCBI chr 7:121,394,541...121,436,935
Ensembl chr 7:121,408,829...121,435,022
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA] CTD PMID:24333275 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of MYC protein] CTD PMID:16005924 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nefh neurofilament heavy increases expression EXP alpha-Tocopherol results in increased expression of NEFH protein modified form CTD PMID:18942769 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein]; [alpha-Tocopherol co-treated with Hydrogen Peroxide] affects the localization of NFE2L2 protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of NFE2L2 protein] CTD PMID:22389237, PMID:31412289, PMID:32134168 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases activity
EXP
ISO
alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of NFKB1 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of [NFKB1 protein binds to RELA protein]]
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]
alpha-Tocopherol results in increased activity of NFKB1 protein
CTD PMID:15025948, PMID:16135673, PMID:17936189, PMID:19083475 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein]; alpha-Tocopherol inhibits the reaction [DCD protein results in increased phosphorylation of NFKBIA protein]
[Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]
alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased phosphorylation of NFKBIA protein]
CTD PMID:16135673, PMID:17532611, PMID:25551565 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased expression of NOS2 protein]
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased expression of NOS2 mRNA]
CTD PMID:17936189, PMID:19135433 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO alpha-Tocopherol results in increased expression of NOS3 mRNA; alpha-Tocopherol results in increased expression of NOS3 protein CTD PMID:16949522 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO alpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA] CTD PMID:17936189 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP alpha-Tocopherol inhibits the reaction [sodium arsenite results in decreased activity of OGDH protein] CTD PMID:12915223 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO alpha-Tocopherol results in increased expression of ORM1 mRNA; alpha-Tocopherol results in increased expression of ORM1 protein CTD PMID:19000923, PMID:20025956 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Rotenone affects the localization of PARK7 protein] CTD PMID:16439141 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]
alpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]
CTD PMID:14645110, PMID:24448832 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pawr pro-apoptotic WT1 regulator multiple interactions EXP alpha-Tocopherol inhibits the reaction [Nerve Growth Factors deficiency results in increased expression of PAWR mRNA]; alpha-Tocopherol inhibits the reaction [Nerve Growth Factors deficiency results in increased expression of PAWR protein] CTD PMID:10428045 NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
JBrowse link
G Pax3 paired box 3 multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of PAX3 mRNA]
alpha-Tocopherol results in increased expression of PAX3 mRNA
CTD PMID:12739027 NCBI chr 9:84,004,004...84,101,226
Ensembl chr 9:84,005,183...84,101,172
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP alpha-Tocopherol results in decreased expression of PCK1 mRNA CTD PMID:11597575 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] CTD PMID:18603805 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Plg plasminogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [Arsenic promotes the reaction [Humic Substances results in decreased activity of PLG protein]]; alpha-Tocopherol inhibits the reaction [Humic Substances results in decreased activity of PLG protein] CTD PMID:11419606 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pltp phospholipid transfer protein decreases abundance ISO PLTP mutant form results in decreased abundance of alpha-Tocopherol CTD PMID:16675720 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
ISO alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of PPARA mRNA]
alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of PPARA mRNA]
alpha-Tocopherol results in increased expression of PPARA mRNA
CTD PMID:17936189, PMID:29065513 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
increases activity
ISO
EXP
alpha-Tocopherol results in increased expression of PPARG mRNA; alpha-Tocopherol results in increased expression of PPARG protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein]
alpha-Tocopherol results in increased activity of PPARG protein
CTD PMID:11752099, PMID:14521714, PMID:19083475, PMID:22389237, PMID:28062356 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP alpha-Tocopherol results in increased expression of PPIA mRNA CTD PMID:16908007 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein] CTD PMID:17532611 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
ISO
EXP
alpha-Tocopherol metabolite results in decreased activity of PTGS2 protein; alpha-Tocopherol results in decreased activity of PTGS2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein]
CTD PMID:15225597, PMID:22389237 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
multiple interactions
ISO
EXP
alpha-Tocopherol affects the localization of RELA protein
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]
alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of RELA protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of [NFKB1 protein binds to RELA protein]]
CTD PMID:15025948, PMID:16135673, PMID:16882165, PMID:17936189 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of RPS6 protein] CTD PMID:22343715 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA protein; [Tretinoin co-treated with alpha-Tocopherol] results in decreased phosphorylation of RXRA protein CTD PMID:15225641 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sele selectin E multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of SELE protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:12566129, PMID:25551565 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 mRNA; [alpha-Tocopherol co-treated with Paraquat] results in increased expression of SLC7A11 protein CTD PMID:24530478 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Smad4 SMAD family member 4 multiple interactions ISO SMAD4 results in decreased susceptibility to [Fluorouracil co-treated with alpha-Tocopherol] CTD PMID:20562578 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Snca synuclein alpha multiple interactions ISO alpha-Tocopherol inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:16439141 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
EXP
ISO
[alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of SOD1 protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein]
alpha-Tocopherol results in increased expression of SOD1 mRNA; alpha-Tocopherol results in increased expression of SOD1 protein
CTD PMID:19083475, PMID:20194575, PMID:21344382, PMID:22732938 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
increases expression
multiple interactions
EXP alpha-Tocopherol results in decreased expression of SOD2 protein
alpha-Tocopherol results in increased expression of SOD2 mRNA; alpha-Tocopherol results in increased expression of SOD2 protein
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased expression of and results in increased activity of SOD2 protein]
CTD PMID:16135673, PMID:18942769, PMID:20194575, PMID:22732938, PMID:23859036 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression EXP alpha-Tocopherol deficiency results in decreased expression of SRSF2 protein CTD PMID:15247049 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in decreased expression of STAR mRNA] CTD PMID:32134168 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP alpha-Tocopherol results in increased expression of STAT3 mRNA CTD PMID:16908007 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in decreased activity of TERT protein] CTD PMID:20112180 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tgfa transforming growth factor alpha decreases response to substance EXP alpha-Tocopherol results in decreased susceptibility to TGFA protein CTD PMID:7593635 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]
alpha-Tocopherol results in decreased expression of TGFB1 mRNA
CTD PMID:9608545, PMID:14732287 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; alpha-Tocopherol inhibits the reaction [Rotenone results in decreased expression of TH protein] CTD PMID:15790535, PMID:25891525 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects expression
decreases response to substance
decreases expression
ISO
EXP
[alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of TNF protein; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with Lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; alpha-Tocopherol inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; alpha-Tocopherol promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased secretion of TNF protein]
alpha-Tocopherol affects the expression of TNF protein
alpha-Tocopherol results in decreased susceptibility to TNF protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of TNF mRNA]
alpha-Tocopherol results in decreased expression of TNF protein
CTD PMID:10588948, PMID:11805214, PMID:12195823, PMID:15025948, PMID:15630180, PMID:16135673, PMID:16750838, PMID:18191645, PMID:19135038, PMID:19135433, PMID:19735175, PMID:23042730, PMID:25551565, PMID:26332274, PMID:30776390, PMID:31712109, PMID:32134168 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 mRNA]; alpha-Tocopherol inhibits the reaction [arsenite results in increased expression of TP53 protein] CTD PMID:12126965 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [arsenite results in increased expression of TXN1 protein] CTD PMID:21344382 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Hydrogen Peroxide results in increased expression of VCAM1 protein]; alpha-Tocopherol inhibits the reaction [Vehicle Emissions results in increased expression of VCAM1 protein] CTD PMID:12566129, PMID:22313677 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO alpha-Tocopherol analog results in increased expression of XBP1 mRNA CTD PMID:20686688 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions EXP alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA] CTD PMID:26332274 NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
JBrowse link
alpha-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, alpha results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects response to substance
multiple interactions
ISO CYP3A5 gene polymorphism affects the susceptibility to tocotrienol, alpha
tocotrienol, alpha inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; tocotrienol, alpha inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]
CTD PMID:31102695 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha] CTD PMID:15668500 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, alpha binds to and results in increased activity of NR1I2 protein; tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, alpha results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
beta-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP
ISO
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]
beta-Tocopherol affects the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; beta-Tocopherol affects the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]
CTD PMID:12450566, PMID:22389237 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein] CTD PMID:22389237 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein] CTD PMID:22389237 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein] CTD PMID:22389237 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein] CTD PMID:22389237 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
beta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, beta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, beta binds to and results in increased activity of NR1I2 protein; tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, beta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
delta-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein] CTD PMID:22389237 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Tretinoin co-treated with delta-tocopherol] results in increased expression of CRABP2 mRNA CTD PMID:15225641 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA] CTD PMID:22389237 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein] CTD PMID:22389237 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein] CTD PMID:22389237 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein] CTD PMID:22389237 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein] CTD PMID:22389237 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein] CTD PMID:22389237 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA] CTD PMID:22389237 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
delta-tocotrienol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO tocotrienol, delta results in increased expression of ABCB1 CTD PMID:15269186 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of ABCC1 mRNA]
tocotrienol, delta results in increased expression of ABCC1 mRNA
CTD PMID:22185406 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 decreases expression ISO tocotrienol, delta results in decreased expression of ABCD2 mRNA CTD PMID:22185406 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Actl6b actin-like 6B increases expression ISO tocotrienol, delta results in increased expression of ACTL6B mRNA CTD PMID:22185406 NCBI chr12:22,194,595...22,211,107
Ensembl chr12:22,194,618...22,211,080
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
increases expression
ISO tocotrienol, delta promotes the reaction [Lipopolysaccharides results in increased expression of ATP2A2 mRNA]
tocotrienol, delta results in increased expression of ATP2A2 mRNA
CTD PMID:22185406 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO tocotrienol, delta results in decreased expression of CCND1 protein CTD PMID:21453743 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CCND2 mRNA]
tocotrienol, delta results in increased expression of CCND2 mRNA
CTD PMID:22185406 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd40 CD40 molecule multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA]
tocotrienol, delta results in increased expression of CD40 mRNA
CTD PMID:22185406 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd69 Cd69 molecule multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 mRNA]
tocotrienol, delta results in increased expression of CD69 mRNA
CTD PMID:22185406 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cox7b2 cytochrome c oxidase subunit 7B2 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of COX7B2 mRNA]
tocotrienol, delta results in decreased expression of COX7B2 mRNA
CTD PMID:22185406 NCBI chr14:39,256,685...39,368,886
Ensembl chr14:39,368,530...39,368,769
JBrowse link
G Crp C-reactive protein multiple interactions ISO [resveratrol co-treated with pterostilbene co-treated with Quercetin co-treated with tocotrienol, delta co-treated with Niacin] results in decreased expression of CRP protein CTD PMID:24319627 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO tocotrienol, delta results in decreased expression of CTNNB1 protein CTD PMID:21453743 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
affects response to substance
ISO tocotrienol, delta inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; tocotrienol, delta inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]
CYP3A5 gene polymorphism affects the susceptibility to tocotrienol, delta
CTD PMID:31102695 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Gimap1 GTPase, IMAP family member 1 multiple interactions
decreases expression
ISO tocotrienol, delta promotes the reaction [Lipopolysaccharides results in decreased expression of GIMAP1 mRNA]
tocotrienol, delta results in decreased expression of GIMAP1 mRNA
CTD PMID:22185406 NCBI chr 4:78,365,276...78,375,450
Ensembl chr 4:78,371,121...78,375,223
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of ICAM1 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]
CTD PMID:22185406 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO tocotrienol, delta inhibits the reaction [[IFNB1 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:22185406 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions ISO tocotrienol, delta inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:22185406 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of IFNGR1 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of IFNGR1 mRNA]
CTD PMID:22185406 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Il12b interleukin 12B decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of IL12B mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
CTD PMID:22185406 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO tocotrienol, delta results in increased expression of IL1A mRNA CTD PMID:22185406 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
tocotrienol, delta results in increased expression of IL1B mRNA
CTD PMID:22185406 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression
multiple interactions
ISO tocotrienol, delta results in increased expression of IL1RN mRNA
tocotrienol, delta promotes the reaction [Lipopolysaccharides results in increased expression of IL1RN mRNA]
CTD PMID:22185406 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO tocotrienol, delta results in increased expression of IL6 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:22185406 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO tocotrienol, delta results in decreased expression of JUN protein CTD PMID:21453743 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO tocotrienol, delta results in decreased expression of MMP7 protein CTD PMID:21453743 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Lipopolysaccharides inhibits the reaction [tocotrienol, delta results in increased expression of NOS2]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] CTD PMID:21356098, PMID:22185406 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO tocotrienol, delta binds to and results in increased activity of NR1I2 protein; tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein] CTD PMID:15269186 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PHKA2 mRNA]
tocotrienol, delta results in increased expression of PHKA2 mRNA
CTD PMID:22185406 NCBI chr  X:35,970,650...36,926,616 JBrowse link
G Psmb2 proteasome 20S subunit beta 2 decreases expression ISO tocotrienol, delta results in decreased expression of PSMB2 mRNA CTD PMID:22185406 NCBI chr 5:144,702,004...144,734,220
Ensembl chr 5:144,701,949...144,734,257
JBrowse link
G Ptbp2 polypyrimidine tract binding protein 2 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA]
tocotrienol, delta results in increased expression of PTBP2 mRNA
CTD PMID:22185406 NCBI chr 2:223,261,444...223,323,075
Ensembl chr 2:223,262,852...223,322,585
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of RASGRP1 mRNA]
tocotrienol, delta results in increased expression of RASGRP1 mRNA
CTD PMID:22185406 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 decreases expression
multiple interactions
ISO tocotrienol, delta results in decreased expression of RASGRP3 mRNA
tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of RASGRP3 mRNA]
CTD PMID:22185406 NCBI chr 6:21,072,634...21,171,619
Ensembl chr 6:21,072,634...21,135,880
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]
tocotrienol, delta results in decreased expression of SOCS3 mRNA
CTD PMID:22185406 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO Lipopolysaccharides inhibits the reaction [tocotrienol, delta results in increased expression of TNF]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
tocotrienol, delta results in decreased expression of TNF mRNA
CTD PMID:21356098, PMID:22185406 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnp1 transition protein 1 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of TNP1 mRNA]
tocotrienol, delta results in decreased expression of TNP1 mRNA
CTD PMID:22185406 NCBI chr 9:80,294,837...80,295,446
Ensembl chr 9:80,294,840...80,295,446
JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions
increases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of TRAF1 mRNA]
tocotrienol, delta results in increased expression of TRAF1 mRNA
CTD PMID:22185406 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA]
tocotrienol, delta results in decreased expression of UBE2D2A mRNA
CTD PMID:22185406 NCBI chr18:28,561,957...28,603,335
Ensembl chr18:28,594,892...28,603,335
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO tocotrienol, delta results in increased expression of UGT1A1 CTD PMID:15269186 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
ISO tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA]
tocotrienol, delta results in decreased expression of VCAM1 mRNA
CTD PMID:22185406 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Wnt1 Wnt family member 1 decreases expression ISO tocotrienol, delta results in decreased expression of WNT1 protein CTD PMID:21453743 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
gamma-tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO Tocopherols results in decreased activity of ABCC1 protein
Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]
CTD PMID:15617835 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Alb albumin multiple interactions EXP gamma-Tocopherol inhibits the reaction [ALB protein results in increased expression of MUC5AC mRNA] CTD PMID:19389874 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G App amyloid beta precursor protein decreases abundance
multiple interactions
EXP APP protein modified form results in decreased abundance of Tocopherols
resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Tocopherols]
CTD PMID:25654502 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor decreases expression
decreases activity
ISO [Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of AR mRNA; Tocopherols results in decreased expression of AR protein
Tocopherols results in decreased activity of AR protein
CTD PMID:12032296, PMID:16302272 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Tocopherols results in increased expression of ARF3 mRNA CTD PMID:17654050 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Tocopherols results in increased expression of ASPM mRNA CTD PMID:17056531 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Tocopherols results in increased expression of ATP1A2 mRNA CTD PMID:17654050 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Tocopherols results in increased expression of ATP1B2 mRNA CTD PMID:17654050 NCBI chr10:56,205,622...56,211,879
Ensembl chr10:56,205,625...56,211,891
JBrowse link
G Aurka aurora kinase A increases expression ISO Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance
multiple interactions
increases expression
ISO BAX protein results in increased susceptibility to Tocopherols
[Fluorouracil co-treated with gamma-Tocopherol] results in increased expression of BAX mRNA
gamma-Tocopherol results in increased expression of BAX mRNA
CTD PMID:16001965, PMID:31587439 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases expression
decreases response to substance
ISO Tocopherols results in increased expression of BCL2 mRNA; Tocopherols results in increased expression of BCL2 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of BCL2 mRNA
gamma-Tocopherol results in decreased expression of BCL2 mRNA
BCL2 protein results in decreased susceptibility to Tocopherols
CTD PMID:8970189, PMID:16001965, PMID:31587439 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases response to substance ISO BCL2L1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Tocopherols results in increased expression of BIRC5 mRNA CTD PMID:17056531 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO Tocopherols results in increased expression of CAMK2G mRNA CTD PMID:17654050 NCBI chr15:3,936,721...3,995,740
Ensembl chr15:3,936,786...3,995,915
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased activity of CASP3 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]
thermozymocidin inhibits the reaction [gamma-Tocopherol results in increased activity of CASP3 protein]
CTD PMID:15596715, PMID:22389237 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO gamma-Tocopherol results in increased activity of CASP9 protein CTD PMID:15596715 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression ISO gamma-Tocopherol results in increased expression of CAT protein CTD PMID:19115203 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Tocopherols results in increased expression of CCNB2 mRNA CTD PMID:17056531 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO gamma-Tocopherol results in decreased expression of CCND1 mRNA; gamma-Tocopherol results in decreased expression of CCND1 protein; Tocopherols results in decreased expression of CCND1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCND1 mRNA
CTD PMID:12368234, PMID:12504091, PMID:31587439 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions
ISO gamma-Tocopherol results in decreased expression of CCNE1 mRNA; gamma-Tocopherol results in decreased expression of CCNE1 protein; Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 protein
[Fluorouracil co-treated with gamma-Tocopherol] results in decreased expression of CCNE1 mRNA
CTD PMID:12368234, PMID:12504091, PMID:31587439 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Tocopherols results in increased expression of CDC6 mRNA CTD PMID:17056531 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO Tocopherols results in increased expression of CDK1 mRNA CTD PMID:17056531 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein CTD PMID:12504091 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Tocopherols results in increased expression of CDK5R1 mRNA CTD PMID:17654050 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO gamma-Tocopherol results in decreased expression of CDKN1A protein CTD PMID:12368234 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO gamma-Tocopherol results in decreased expression of CDKN1B protein CTD PMID:12368234 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO gamma-Tocopherol results in decreased expression of CDKN2A protein CTD PMID:12368234 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Tocopherols results in increased expression of CLEC4E mRNA CTD PMID:17056531 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cplx1 complexin 1 increases expression ISO Tocopherols results in increased expression of CPLX1 mRNA CTD PMID:17654050 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598
JBrowse link
G Cplx2 complexin 2 increases expression ISO Tocopherols results in increased expression of CPLX2 mRNA CTD PMID:17654050 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Tretinoin co-treated with gamma-Tocopherol] results in increased expression of CRABP2 mRNA CTD PMID:15225641 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Crp C-reactive protein multiple interactions ISO [alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of CRP protein CTD PMID:18191645 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Tocopherols results in increased expression of CSF1R mRNA CTD PMID:17056531 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO Tocopherols results in increased expression of CSRP2 mRNA CTD PMID:17056531 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CYP1A1 mRNA] CTD PMID:22389237 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Tocopherols results in increased expression of DNAJC5 mRNA CTD PMID:17654050 NCBI chr 3:177,012,714...177,047,787
Ensembl chr 3:177,013,604...177,043,902
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egr1 early growth response 1 decreases activity ISO Tocopherols results in decreased activity of EGR1 protein CTD PMID:15878867 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR1 protein] CTD PMID:22389237 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA] CTD PMID:22389237 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia increases expression ISO Tocopherols results in increased expression of FCER1A mRNA CTD PMID:17056531 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase increases expression ISO Tocopherols results in increased expression of FES mRNA CTD PMID:17056531 NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Tocopherols results in decreased expression of FGF1 mRNA CTD PMID:15878867 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Tocopherols results in decreased expression of FGF2 mRNA CTD PMID:15878867 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Tocopherols results in decreased expression of FGFR1 mRNA CTD PMID:15144885 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 increases expression ISO Tocopherols results in increased expression of FKBP9 mRNA CTD PMID:17056531 NCBI chr 4:87,167,514...87,234,198
Ensembl chr 4:87,167,514...87,234,197
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of FOS mRNA; Tocopherols results in increased expression of FOS protein CTD PMID:8970189 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Tocopherols results in increased expression of GRIA2 mRNA CTD PMID:17654050 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of GSTM1 mRNA; gamma-Tocopherol results in increased expression of GSTM1 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]
CTD PMID:19115203, PMID:22389237 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases activity ISO Tocopherols results in decreased activity of GSTO1 protein CTD PMID:16781109 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Tocopherols results in increased expression of HASPIN mRNA CTD PMID:17056531 NCBI chr10:59,695,403...59,698,398
Ensembl chr10:59,695,913...59,698,168
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of HMOX1 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of HMOX1 protein]
CTD PMID:19115203, PMID:22389237 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of JUN mRNA; Tocopherols results in increased expression of JUN protein CTD PMID:8970189 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Tocopherols results in increased expression of KIF20A mRNA CTD PMID:17056531 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif4a kinesin family member 4A increases expression ISO Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases response to substance ISO MCL1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP gamma-Tocopherol inhibits the reaction [ALB protein results in increased expression of MUC5AC mRNA] CTD PMID:19389874 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
decreases activity
ISO Tocopherols results in decreased expression of MYC mRNA
Tocopherols results in decreased activity of MYC protein
CTD PMID:8970189 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Napb NSF attachment protein beta increases expression ISO Tocopherols results in increased expression of NAPB mRNA CTD PMID:17654050 NCBI chr 3:143,017,571...143,063,904
Ensembl chr 3:143,020,454...143,063,983
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of NFE2L2 mRNA; gamma-Tocopherol results in increased expression of NFE2L2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NFE2L2 protein]
CTD PMID:19115203, PMID:22389237 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of NQO1 protein] CTD PMID:22389237 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Tocopherols results in increased expression of NSF mRNA CTD PMID:17654050 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression
EXP [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PCNA protein]
Tocopherols results in decreased expression of PCNA
CTD PMID:17927505, PMID:22389237 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of PPARG mRNA; gamma-Tocopherol results in increased expression of PPARG protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG mRNA]; [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PPARG protein]
CTD PMID:14521714, PMID:22389237 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Tocopherols results in increased expression of PPP3CA mRNA CTD PMID:17654050 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Prtn3 proteinase 3 increases expression ISO Tocopherols results in increased expression of PRTN3 mRNA CTD PMID:17056531 NCBI chr 7:12,643,712...12,646,951
Ensembl chr 7:12,643,516...12,646,960
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
ISO
EXP
gamma-Tocopherol results in decreased activity of PTGS2 protein
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of PTGS2 protein]
CTD PMID:15225597, PMID:22389237 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression ISO Tocopherols results in increased expression of PTPRO mRNA CTD PMID:17056531 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB11B mRNA CTD PMID:17654050 NCBI chr 7:18,598,991...18,612,132
Ensembl chr 7:18,598,880...18,612,147
JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB3A mRNA CTD PMID:17654050 NCBI chr16:20,435,098...20,439,206
Ensembl chr16:20,435,101...20,439,206
JBrowse link
G Rab6b RAB6B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB6B mRNA CTD PMID:17654050 NCBI chr 8:111,600,375...111,668,817
Ensembl chr 8:111,600,532...111,668,808
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression ISO Tocopherols results in increased expression of RRM1 mRNA CTD PMID:17056531 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Snca synuclein alpha increases expression ISO Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncb synuclein, beta increases expression ISO Tocopherols results in increased expression of SNCB mRNA CTD PMID:17654050 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO gamma-Tocopherol results in increased expression of SOD1 protein CTD PMID:19115203 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Stx1a syntaxin 1A increases expression ISO Tocopherols results in increased expression of STX1A mRNA CTD PMID:17654050 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression ISO Tocopherols results in increased expression of STXBP1 mRNA CTD PMID:17654050 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Sv2a synaptic vesicle glycoprotein 2a increases expression ISO Tocopherols results in increased expression of SV2A mRNA CTD PMID:17654050 NCBI chr 2:198,321,100...198,336,889
Ensembl chr 2:198,321,142...198,336,913
JBrowse link
G Syn1 synapsin I increases expression ISO Tocopherols results in increased expression of SYN1 mRNA CTD PMID:17654050 NCBI chr  X:1,321,315...1,379,202
Ensembl chr  X:1,321,315...1,379,198
JBrowse link
G Syn2 synapsin II increases expression ISO Tocopherols results in increased expression of SYN2 mRNA CTD PMID:17654050 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Syngr1 synaptogyrin 1 increases expression ISO Tocopherols results in increased expression of SYNGR1 mRNA CTD PMID:17654050 NCBI chr 7:121,311,008...121,334,437
Ensembl chr 7:121,311,024...121,334,437
JBrowse link
G Syp synaptophysin increases expression ISO Tocopherols results in increased expression of SYP mRNA CTD PMID:17654050 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Syt11 synaptotagmin 11 increases expression ISO Tocopherols results in increased expression of SYT11 mRNA CTD PMID:17654050 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt13 synaptotagmin 13 increases expression ISO Tocopherols results in increased expression of SYT13 mRNA CTD PMID:17654050 NCBI chr 3:81,814,287...81,852,454
Ensembl chr 3:81,814,261...81,854,605
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
[alpha-Tocopherol co-treated with gamma-Tocopherol] results in decreased expression of TNF protein
Tocopherols inhibits the reaction [TNF protein results in decreased export of Potassium]
CTD PMID:17337591, PMID:18191645 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Tocopherols results in increased expression of TNFAIP2 mRNA CTD PMID:17056531 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Tp53 tumor protein p53 increases activity ISO Tocopherols results in increased activity of TP53 protein CTD PMID:15883045 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 increases expression ISO Tocopherols results in increased expression of TTC3 mRNA CTD PMID:17654050 NCBI chr11:34,598,324...34,739,986
Ensembl chr11:34,598,492...34,738,791
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions
ISO
EXP
gamma-Tocopherol results in increased expression of UGT1A1 mRNA
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of UGT1A1 mRNA]
CTD PMID:19115203, PMID:22389237 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 increases expression ISO Tocopherols results in increased expression of VAMP2 mRNA CTD PMID:17654050 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vdr vitamin D receptor increases expression ISO Tocopherols results in increased expression of VDR mRNA CTD PMID:12032296 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
tocopherol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]
Tocopherols results in decreased activity of ABCC1 protein
CTD PMID:15617835 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases abundance
EXP resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Tocopherols] CTD PMID:25654502 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor decreases activity
decreases expression
ISO Tocopherols results in decreased activity of AR protein
[Tocopherols results in decreased expression of AR protein] which results in decreased expression of KLK3 protein; Tocopherols results in decreased expression of AR mRNA; Tocopherols results in decreased expression of AR protein
CTD PMID:12032296, PMID:16302272 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Tocopherols results in increased expression of ARF3 mRNA CTD PMID:17654050 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Tocopherols results in increased expression of ASPM mRNA CTD PMID:17056531 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression ISO Tocopherols results in increased expression of ATP1A2 mRNA CTD PMID:17654050 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression ISO Tocopherols results in increased expression of ATP1B2 mRNA CTD PMID:17654050 NCBI chr10:56,205,622...56,211,879
Ensembl chr10:56,205,625...56,211,891
JBrowse link
G Aurka aurora kinase A increases expression ISO Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance ISO BAX protein results in increased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
increases expression
ISO BCL2 protein results in decreased susceptibility to Tocopherols
Tocopherols results in increased expression of BCL2 mRNA; Tocopherols results in increased expression of BCL2 protein
CTD PMID:8970189, PMID:16001965 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases response to substance ISO BCL2L1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Tocopherols results in increased expression of BIRC5 mRNA CTD PMID:17056531 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO Tocopherols results in increased expression of CAMK2G mRNA CTD PMID:17654050 NCBI chr15:3,936,721...3,995,740
Ensembl chr15:3,936,786...3,995,915
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Tocopherols results in increased expression of CCNB2 mRNA CTD PMID:17056531 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Tocopherols results in decreased expression of CCND1 protein CTD PMID:12504091 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Tocopherols results in decreased expression of CCND3 protein CTD PMID:12504091 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Tocopherols results in decreased expression of CCNE1 mRNA; Tocopherols results in decreased expression of CCNE1 protein CTD PMID:12504091 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Tocopherols results in increased expression of CDC6 mRNA CTD PMID:17056531 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO Tocopherols results in increased expression of CDK1 mRNA CTD PMID:17056531 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Tocopherols results in decreased expression of CDK2 protein CTD PMID:12504091 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein CTD PMID:12504091 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Tocopherols results in increased expression of CDK5R1 mRNA CTD PMID:17654050 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Tocopherols results in increased expression of CLEC4E mRNA CTD PMID:17056531 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cplx1 complexin 1 increases expression ISO Tocopherols results in increased expression of CPLX1 mRNA CTD PMID:17654050 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598
JBrowse link
G Cplx2 complexin 2 increases expression ISO Tocopherols results in increased expression of CPLX2 mRNA CTD PMID:17654050 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Tocopherols results in increased expression of CSF1R mRNA CTD PMID:17056531 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO Tocopherols results in increased expression of CSRP2 mRNA CTD PMID:17056531 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 increases expression ISO Tocopherols results in increased expression of DNAJC5 mRNA CTD PMID:17654050 NCBI chr 3:177,012,714...177,047,787
Ensembl chr 3:177,013,604...177,043,902
JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egr1 early growth response 1 decreases activity ISO Tocopherols results in decreased activity of EGR1 protein CTD PMID:15878867 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia increases expression ISO Tocopherols results in increased expression of FCER1A mRNA CTD PMID:17056531 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase increases expression ISO Tocopherols results in increased expression of FES mRNA CTD PMID:17056531 NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Tocopherols results in decreased expression of FGF1 mRNA CTD PMID:15878867 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Tocopherols results in decreased expression of FGF2 mRNA CTD PMID:15878867 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Tocopherols results in decreased expression of FGFR1 mRNA CTD PMID:15144885 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 increases expression ISO Tocopherols results in increased expression of FKBP9 mRNA CTD PMID:17056531 NCBI chr 4:87,167,514...87,234,198
Ensembl chr 4:87,167,514...87,234,197
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of FOS mRNA; Tocopherols results in increased expression of FOS protein CTD PMID:8970189 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Tocopherols results in increased expression of GRIA2 mRNA CTD PMID:17654050 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO Tocopherols results in increased expression of GRIN1 mRNA CTD PMID:17654050 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases activity ISO Tocopherols results in decreased activity of GSTO1 protein CTD PMID:16781109 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Tocopherols results in increased expression of HASPIN mRNA CTD PMID:17056531 NCBI chr10:59,695,403...59,698,398
Ensembl chr10:59,695,913...59,698,168
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tocopherols results in increased expression of JUN mRNA; Tocopherols results in increased expression of JUN protein CTD PMID:8970189 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Tocopherols results in increased expression of KIF20A mRNA CTD PMID:17056531 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif4a kinesin family member 4A increases expression ISO Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases response to substance ISO MCL1 protein results in decreased susceptibility to Tocopherols CTD PMID:16001965 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases activity
decreases expression
ISO Tocopherols results in decreased activity of MYC protein
Tocopherols results in decreased expression of MYC mRNA
CTD PMID:8970189 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Napb NSF attachment protein beta increases expression ISO Tocopherols results in increased expression of NAPB mRNA CTD PMID:17654050 NCBI chr 3:143,017,571...143,063,904
Ensembl chr 3:143,020,454...143,063,983
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases expression ISO Tocopherols results in increased expression of NSF mRNA CTD PMID:17654050 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP Tocopherols results in decreased expression of PCNA CTD PMID:17927505 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Tocopherols results in increased expression of PPP3CA mRNA CTD PMID:17654050 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Prtn3 proteinase 3 increases expression ISO Tocopherols results in increased expression of PRTN3 mRNA CTD PMID:17056531 NCBI chr 7:12,643,712...12,646,951
Ensembl chr 7:12,643,516...12,646,960
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression ISO Tocopherols results in increased expression of PTPRO mRNA CTD PMID:17056531 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
JBrowse link
G Rab11b RAB11B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB11B mRNA CTD PMID:17654050 NCBI chr 7:18,598,991...18,612,132
Ensembl chr 7:18,598,880...18,612,147
JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB3A mRNA CTD PMID:17654050 NCBI chr16:20,435,098...20,439,206
Ensembl chr16:20,435,101...20,439,206
JBrowse link
G Rab6b RAB6B, member RAS oncogene family increases expression ISO Tocopherols results in increased expression of RAB6B mRNA CTD PMID:17654050 NCBI chr 8:111,600,375...111,668,817
Ensembl chr 8:111,600,532...111,668,808
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Tocopherols results in decreased phosphorylation of RB1 protein CTD PMID:12504091 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression ISO Tocopherols results in increased expression of RRM1 mRNA CTD PMID:17056531 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Snca synuclein alpha increases expression ISO Tocopherols results in increased expression of SNCA mRNA CTD PMID:17654050 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncb synuclein, beta increases expression ISO Tocopherols results in increased expression of SNCB mRNA CTD PMID:17654050 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Stx1a syntaxin 1A increases expression ISO Tocopherols results in increased expression of STX1A mRNA CTD PMID:17654050 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression ISO Tocopherols results in increased expression of STXBP1 mRNA CTD PMID:17654050 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Sv2a synaptic vesicle glycoprotein 2a increases expression ISO Tocopherols results in increased expression of SV2A mRNA CTD PMID:17654050 NCBI chr 2:198,321,100...198,336,889
Ensembl chr 2:198,321,142...198,336,913
JBrowse link
G Syn1 synapsin I increases expression ISO Tocopherols results in increased expression of SYN1 mRNA CTD PMID:17654050 NCBI chr  X:1,321,315...1,379,202
Ensembl chr  X:1,321,315...1,379,198
JBrowse link
G Syn2 synapsin II increases expression ISO Tocopherols results in increased expression of SYN2 mRNA CTD PMID:17654050 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Syngr1 synaptogyrin 1 increases expression ISO Tocopherols results in increased expression of SYNGR1 mRNA CTD PMID:17654050 NCBI chr 7:121,311,008...121,334,437
Ensembl chr 7:121,311,024...121,334,437
JBrowse link
G Syp synaptophysin increases expression ISO Tocopherols results in increased expression of SYP mRNA CTD PMID:17654050 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Syt11 synaptotagmin 11 increases expression ISO Tocopherols results in increased expression of SYT11 mRNA CTD PMID:17654050 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt13 synaptotagmin 13 increases expression ISO Tocopherols results in increased expression of SYT13 mRNA CTD PMID:17654050 NCBI chr 3:81,814,287...81,852,454
Ensembl chr 3:81,814,261...81,854,605
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Tocopherols inhibits the reaction [TNF protein results in decreased export of Potassium] CTD PMID:17337591 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Tocopherols results in increased expression of TNFAIP2 mRNA CTD PMID:17056531 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Tp53 tumor protein p53 increases activity ISO Tocopherols results in increased activity of TP53 protein CTD PMID:15883045 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 increases expression ISO Tocopherols results in increased expression of TTC3 mRNA CTD PMID:17654050 NCBI chr11:34,598,324...34,739,986
Ensembl chr11:34,598,492...34,738,791
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 increases expression ISO Tocopherols results in increased expression of VAMP2 mRNA CTD PMID:17654050 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vdr vitamin D receptor increases expression ISO Tocopherols results in increased expression of VDR mRNA CTD PMID:12032296 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
vitamin E term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aamp angio-associated, migratory cell protein increases expression ISO Vitamin E results in increased expression of AAMP mRNA CTD PMID:19244175 NCBI chr 9:81,560,836...81,566,642
Ensembl chr 9:81,560,842...81,566,642
JBrowse link
G Aass aminoadipate-semialdehyde synthase multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNA
Vitamin E results in decreased expression of AASS mRNA
CTD PMID:19244175 NCBI chr 4:50,152,005...50,208,935
Ensembl chr 4:50,152,452...50,200,328
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP alpha-Tocopherol inhibits the reaction [nickel chloride results in increased expression of ABCB1 protein] CTD PMID:24448832 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA CTD PMID:11444866 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD1 mRNA] CTD PMID:29065513 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 multiple interactions ISO alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased expression of ABCD3 mRNA] CTD PMID:29065513 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Abhd14a abhydrolase domain containing 14A decreases expression ISO Vitamin E results in decreased expression of ABHD14A mRNA CTD PMID:19244175 NCBI chr 8:115,141,575...115,151,222
Ensembl chr 8:115,141,539...115,149,527
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression
increases expression
ISO Vitamin E results in decreased expression of ABHD2 mRNA
Vitamin E results in increased expression of ABHD2 mRNA
CTD PMID:19244175 NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Vitamin E results in increased expression of ABHD4 mRNA CTD PMID:19244175 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression ISO Vitamin E results in increased expression of ACAA2 mRNA CTD PMID:19244175 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ACADS mRNA
Vitamin E results in increased expression of ACADS mRNA
CTD PMID:19244175 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [iron(II)-ascorbic acid complex results in decreased activity of ACAT1 protein] CTD PMID:10656290 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
[Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]
CTD PMID:11814146, PMID:19464315, PMID:20663516, PMID:23619517 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aco2 aconitase 2 increases expression ISO Vitamin E results in increased expression of ACO2 mRNA CTD PMID:19244175 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ACOT2 mRNA
Vitamin E results in increased expression of ACOT2 mRNA
CTD PMID:19244175 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acp1 acid phosphatase 1 decreases expression ISO Vitamin E results in decreased expression of ACP1 mRNA CTD PMID:19244175 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Vitamin E results in decreased expression of ACTA2 mRNA CTD PMID:19244175 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta increases expression ISO Vitamin E results in increased expression of ACTB mRNA CTD PMID:19244175 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actn4 actinin alpha 4 increases expression ISO Vitamin E results in increased expression of ACTN4 mRNA CTD PMID:19244175 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Actr1a actin related protein 1A increases expression ISO Vitamin E results in increased expression of ACTR1A mRNA CTD PMID:19244175 NCBI chr 1:266,123,864...266,142,621
Ensembl chr 1:266,123,870...266,142,538
JBrowse link
G Actr1b actin related protein 1B increases expression ISO Vitamin E results in increased expression of ACTR1B mRNA CTD PMID:19244175 NCBI chr 9:43,267,053...43,276,717
Ensembl chr 9:43,267,057...43,276,685
JBrowse link
G Acvr2a activin A receptor type 2A decreases expression ISO Vitamin E results in decreased expression of ACVR2A mRNA CTD PMID:19244175 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP alpha-Tocopherol results in increased expression of ACVRL1 mRNA CTD PMID:16908007 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression ISO Vitamin E results in decreased expression of ADAM17 mRNA CTD PMID:19244175 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression ISO Vitamin E results in decreased expression of ADAMTS5 mRNA CTD PMID:19244175 NCBI chr11:25,411,174...25,456,639
Ensembl chr11:25,410,975...25,456,836
JBrowse link
G Adap1 ArfGAP with dual PH domains 1 increases expression ISO Vitamin E results in increased expression of ADAP1 mRNA CTD PMID:19244175 NCBI chr12:17,416,327...17,468,212
Ensembl chr12:17,416,327...17,468,212
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 decreases expression ISO Vitamin E results in decreased expression of ADARB1 mRNA CTD PMID:19244175 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Adcy2 adenylate cyclase 2 multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of ADCY2 mRNA CTD PMID:19244175 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression ISO Vitamin E results in increased expression of ADCY6 mRNA CTD PMID:19244175 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Add1 adducin 1 increases expression ISO Vitamin E results in increased expression of ADD1 mRNA CTD PMID:19244175 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Add3 adducin 3 decreases expression ISO Vitamin E results in decreased expression of ADD3 mRNA CTD PMID:19244175 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 increases expression ISO Vitamin E results in increased expression of ADGRB1 mRNA CTD PMID:19244175 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression ISO Vitamin E results in decreased expression of ADH7 mRNA CTD PMID:19244175 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ mRNA]; Vitamin E inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein] CTD PMID:20404018 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adra2c adrenoceptor alpha 2C increases expression ISO Vitamin E results in increased expression of ADRA2C mRNA CTD PMID:19244175 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Adrm1 adhesion regulating molecule 1 increases expression ISO Vitamin E results in increased expression of ADRM1 mRNA CTD PMID:19244175 NCBI chr 3:175,548,181...175,552,943
Ensembl chr 3:175,548,174...175,552,947
JBrowse link
G Aebp1 AE binding protein 1 increases expression ISO Vitamin E results in increased expression of AEBP1 mRNA CTD PMID:19244175 NCBI chr14:86,101,253...86,111,323
Ensembl chr14:86,101,277...86,111,306
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO Vitamin E results in increased expression of AEN mRNA CTD PMID:19244175 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 multiple interactions ISO [Selenium co-treated with Vitamin E] results in decreased expression of AGPAT2 mRNA CTD PMID:19244175 NCBI chr 3:4,044,741...4,055,384
Ensembl chr 3:4,044,542...4,055,806
JBrowse link
G Agrn agrin decreases expression ISO Vitamin E results in decreased expression of AGRN mRNA CTD PMID:19244175 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Agt angiotensinogen multiple interactions ISO alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein]; alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtpbp1 ATP/GTP binding protein 1 decreases expression ISO Vitamin E results in decreased expression of AGTPBP1 mRNA CTD PMID:19244175 NCBI chr17:5,510,009...5,614,416
Ensembl chr17:5,511,385...5,614,435
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Vitamin E results in increased expression of AHNAK mRNA CTD PMID:19244175 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO Vitamin E results in increased expression of AHNAK2 mRNA CTD PMID:19244175 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Vitamin E results in decreased expression of AHR mRNA CTD PMID:19244175 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression ISO Vitamin E results in increased expression of AHSA1 mRNA CTD PMID:19244175 NCBI chr 6:111,296,168...111,304,224
Ensembl chr 6:111,296,417...111,304,224
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of AIMP1 mRNA
Vitamin E results in decreased expression of AIMP1 mRNA
CTD PMID:19244175 NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378
JBrowse link
G Ak1 adenylate kinase 1 increases expression ISO Vitamin E results in increased expression of AK1 mRNA CTD PMID:19244175 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Ak3 adenylate kinase 3 multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of AK3 mRNA CTD PMID:19244175 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akap13 A-kinase anchoring protein 13 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of AKAP13 mRNA
Vitamin E results in decreased expression of AKAP13 mRNA
CTD PMID:19244175 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Akap2 A-kinase anchoring protein 2 increases expression
decreases expression
ISO Vitamin E results in increased expression of PALM2AKAP2 mRNA
Vitamin E results in decreased expression of PALM2AKAP2 mRNA
CTD PMID:19244175 NCBI chr 5:74,874,245...74,985,789
Ensembl chr 5:74,874,306...74,982,401
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP
ISO
alpha-Tocopherol results in increased expression of AKR1B1 mRNA
Vitamin E results in increased expression of AKR1B1 mRNA
CTD PMID:16908007, PMID:19244175 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Vitamin E results in increased expression of AKR1C2 mRNA CTD PMID:19244175 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of AKT1 protein]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
Vitamin E results in increased expression of AKT1 mRNA
CTD PMID:19244175, PMID:19351882, PMID:21911000, PMID:22343715 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO
EXP
alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein]
Vitamin E inhibits the reaction [lead acetate results in decreased activity of ALAD protein]
CTD PMID:2604901, PMID:7728901 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions EXP alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin multiple interactions ISO
EXP
Vitamin E inhibits the reaction [Ethanol results in decreased expression of ALB protein]
[Quercetin co-treated with Vitamin E] inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]; alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]; sodium-4,5-dihydroxy-1,3-benzene disulfonate promotes the reaction [alpha-Tocopherol inhibits the reaction [beryllium nitrate results in decreased expression of ALB protein]]; Vitamin E inhibits the reaction [Cyclosporine results in decreased expression of ALB protein]
Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]
CTD PMID:17429802, PMID:17927767, PMID:21086752, PMID:23348005 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Vitamin E results in decreased expression of ALDH6A1 mRNA CTD PMID:19244175 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Vitamin E results in increased expression of ALDOA mRNA CTD PMID:19244175 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase increases expression ISO Vitamin E results in increased expression of ALG3 mRNA CTD PMID:19244175 NCBI chr11:83,985,484...83,991,706
Ensembl chr11:83,986,230...83,991,706
JBrowse link
G Alg9 ALG9, alpha-1,2-mannosyltransferase multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of ALG9 mRNA CTD PMID:19244175 NCBI chr 8:55,202,140...55,265,478
Ensembl chr 8:55,202,725...55,265,478
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase decreases expression ISO Vitamin E results in decreased expression of ALKBH1 mRNA CTD PMID:19244175 NCBI chr 6:111,456,096...111,476,829
Ensembl chr 6:111,456,187...111,477,090
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity
multiple interactions
ISO
EXP
Vitamin E results in decreased activity of ALOX5 protein
[Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein
CTD PMID:11325678, PMID:12200813, PMID:22223226 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 increases expression ISO Vitamin E results in increased expression of AMBRA1 mRNA CTD PMID:19244175 NCBI chr 3:80,634,470...80,830,068
Ensembl chr 3:80,634,470...80,830,068
JBrowse link
G Anapc15 anaphase promoting complex subunit 15 increases expression ISO Vitamin E results in increased expression of ANAPC15 mRNA CTD PMID:19244175 NCBI chr 1:166,981,738...166,985,363
Ensembl chr 1:166,983,175...166,985,054
JBrowse link
G Andpro androgen regulated protein decreases expression EXP Vitamin E results in decreased expression of ANDPRO mRNA CTD PMID:15084515 NCBI chr 3:143,893,005...143,899,609
Ensembl chr 3:143,893,006...143,899,370
JBrowse link
G Angpt1 angiopoietin 1 decreases expression ISO Vitamin E results in decreased expression of ANGPT1 mRNA CTD PMID:19244175 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Ank3 ankyrin 3 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNA
Vitamin E results in decreased expression of ANK3 mRNA
CTD PMID:19244175 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Ankrd12 ankyrin repeat domain 12 decreases expression ISO Vitamin E results in decreased expression of ANKRD12 mRNA CTD PMID:19244175 NCBI chr 9:113,605,683...113,682,482
Ensembl chr 9:113,605,657...113,682,482
JBrowse link
G Ano6 anoctamin 6 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Ozone results in increased expression of ANO6 mRNA] CTD PMID:27886375 NCBI chr 7:137,142,063...137,335,208
Ensembl chr 7:137,142,170...137,335,208
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ANP32B mRNA
Vitamin E results in decreased expression of ANP32B mRNA
CTD PMID:19244175 NCBI chr 5:62,070,709...62,094,633
Ensembl chr 5:62,071,346...62,094,633
JBrowse link
G Anxa6 annexin A6 increases expression ISO Vitamin E results in increased expression of ANXA6 mRNA CTD PMID:19244175 NCBI chr10:40,320,581...40,375,605
Ensembl chr10:40,320,581...40,375,605
JBrowse link
G Ap1m2 adaptor related protein complex 1 subunit mu 2 increases expression ISO Vitamin E results in increased expression of AP1M2 mRNA CTD PMID:19244175 NCBI chr 8:22,318,941...22,336,827
Ensembl chr 8:22,319,331...22,336,794
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 increases expression ISO Vitamin E results in increased expression of AP2A2 mRNA CTD PMID:19244175 NCBI chr 1:214,534,217...214,607,497
Ensembl chr 1:214,534,284...214,606,169
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression ISO Vitamin E results in increased expression of AP2M1 mRNA CTD PMID:19244175 NCBI chr11:84,041,184...84,047,542
Ensembl chr11:84,041,184...84,047,546
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 increases expression ISO Vitamin E results in increased expression of AP2S1 mRNA CTD PMID:19244175 NCBI chr 1:78,671,238...78,682,847
Ensembl chr 1:78,671,121...78,682,871
JBrowse link
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 increases expression ISO Vitamin E results in increased expression of AP3S2 mRNA CTD PMID:19244175 NCBI chr 1:141,612,961...141,655,417
Ensembl chr 1:141,612,963...141,655,894
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 decreases expression ISO Vitamin E results in decreased expression of APBB2 mRNA CTD PMID:19244175 NCBI chr14:43,205,047...43,526,968
Ensembl chr14:43,512,901...43,523,080
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Vitamin E results in increased expression of APEX1 mRNA CTD PMID:19244175 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 multiple interactions
decreases expression
EXP alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA]
alpha-Tocopherol results in decreased expression of APEX2 mRNA
CTD PMID:26332274 NCBI chr  X:23,146,085...23,166,676
Ensembl chr  X:23,146,085...23,166,675
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 increases expression ISO Vitamin E results in increased expression of APLP2 mRNA CTD PMID:19244175 NCBI chr 8:32,298,526...32,328,821
Ensembl chr 8:32,298,532...32,328,839
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
increases expression
decreases activity
ISO
EXP
alpha-Tocopherol results in decreased expression of APOA1 mRNA; alpha-Tocopherol results in decreased expression of APOA1 protein
Vitamin E results in increased expression of APOA1 protein
alpha-Tocopherol results in decreased activity of APOA1 promoter
CTD PMID:16423621, PMID:18458655 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; alpha-Tocopherol promotes the reaction [APOB protein results in increased reduction of Copper]; Vitamin E promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Vitamin E promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]] CTD PMID:11368321, PMID:17237316, PMID:17475462 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO Vitamin E inhibits the reaction [APOE mutant form results in increased abundance of 8,12-iso-isoprostane F2alpha-VI] CTD PMID:16303615 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apol3 apolipoprotein L, 3 increases expression ISO Vitamin E results in increased expression of APOL3 mRNA CTD PMID:19244175 NCBI chr 7:118,685,022...118,694,016
Ensembl chr 7:118,685,022...118,694,015
JBrowse link
G Apom apolipoprotein M increases expression ISO Vitamin E results in increased expression of APOM mRNA CTD PMID:19244175 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases expression
ISO
EXP
alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein]
Vitamin E inhibits the reaction [APP protein modified form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]
Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein]
Vitamin E results in decreased expression of APP mRNA
CTD PMID:12039845, PMID:12117551, PMID:12684028, PMID:15223066, PMID:19244175 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of APPBP2 mRNA
Vitamin E results in increased expression of APPBP2 mRNA
CTD PMID:19244175 NCBI chr10:72,503,347...72,545,141
Ensembl chr10:72,503,347...72,545,141
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Vitamin E results in increased expression of AQP1 mRNA CTD PMID:19244175 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression
multiple interactions
ISO Vitamin E results in increased expression of AQP3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AQP3 mRNA
CTD PMID:19244175 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP
ISO
Vitamin E inhibits the reaction [manganese(III) acetate dihydrate results in increased expression of AQP4 protein]
Vitamin E inhibits the reaction [[ferrous chloride results in increased abundance of Iron] which results in increased expression of AQP4 protein]
CTD PMID:20648640, PMID:30914277 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase multiple interactions ISO [Selenium co-treated with Vitamin E] results in increased expression of ARAF mRNA CTD PMID:19244175 NCBI chr  X:1,369,534...1,391,603
Ensembl chr  X:1,379,194...1,390,873
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Vitamin E results in increased expression of ARF3 mRNA CTD PMID:19244175 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arf5 ADP-ribosylation factor 5 increases expression ISO Vitamin E results in increased expression of ARF5 mRNA CTD PMID:19244175 NCBI chr 4:55,715,744...55,718,670
Ensembl chr 4:55,715,744...55,718,670
JBrowse link
G Arhgap10 Rho GTPase activating protein 10 increases expression ISO Vitamin E results in increased expression of ARHGAP10 mRNA CTD PMID:19244175 NCBI chr19:34,138,978...34,406,593
Ensembl chr19:34,139,997...34,402,436
JBrowse link
G Arhgap8 Rho GTPase activating protein 8 increases expression ISO Vitamin E results in increased expression of ARHGAP8 mRNA CTD PMID:19244175 NCBI chr 7:125,732,300...125,797,149
Ensembl chr 7:125,731,275...125,795,980
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Vitamin E results in increased expression of ARHGDIA mRNA CTD PMID:19244175 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 decreases expression ISO Vitamin E results in decreased expression of ARIH1 mRNA CTD PMID:19244175 NCBI chr 8:64,166,359...64,268,555
Ensembl chr 8:64,166,360...64,268,555
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D increases expression ISO Vitamin E results in increased expression of ARL4D mRNA CTD PMID:19244175 NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 increases expression ISO Vitamin E results in increased expression of ARL6IP4 mRNA CTD PMID:19244175 NCBI chr12:37,904,376...37,906,521
Ensembl chr12:37,904,379...37,906,521
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression ISO Vitamin E results in increased expression of ARPC1A mRNA CTD PMID:19244175 NCBI chr12:11,272,609...11,294,084
Ensembl chr12:11,272,609...11,294,058
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Vitamin E results in increased expression of ARPC4 mRNA CTD PMID:19244175 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 increases expression ISO Vitamin E results in increased expression of ASAP3 mRNA CTD PMID:19244175 NCBI chr 5:154,551,901...154,596,125
Ensembl chr 5:154,552,195...154,594,785
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ASB1 mRNA
Vitamin E results in increased expression of ASB1 mRNA
CTD PMID:19244175 NCBI chr 9:98,668,231...98,689,471
Ensembl chr 9:98,668,231...98,684,900
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 decreases expression ISO Vitamin E results in decreased expression of ASXL1 mRNA CTD PMID:19244175 NCBI chr 3:148,832,231...148,902,356
Ensembl chr 3:148,837,814...148,900,452
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
ISO alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased phosphorylation of ATF2 protein]
Vitamin E results in increased phosphorylation of ATF2 protein
CTD PMID:11522656, PMID:14645110 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf3 activating transcription factor 3 decreases expression ISO Vitamin E results in decreased expression of ATF3 mRNA CTD PMID:19244175 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf5 activating transcription factor 5 multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ATF5 mRNA
Vitamin E results in increased expression of ATF5 mRNA
CTD PMID:19244175 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atg12 autophagy related 12 decreases expression ISO Vitamin E results in decreased expression of ATG12 mRNA CTD PMID:19244175 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atmin ATM interactor multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of ATMIN mRNA
Vitamin E results in decreased expression of ATMIN mRNA
CTD PMID:19244175 NCBI chr19:49,482,482...49,499,682 JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression ISO Vitamin E results in increased expression of ATOX1 mRNA CTD PMID:19244175 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO Vitamin E results in increased expression of ATP5F1B mRNA CTD PMID:19244175 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Vitamin E results in decreased expression of ATP5F1C mRNA CTD PMID:19244175 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp5me ATP synthase membrane subunit e decreases expression ISO Vitamin E results in decreased expression of ATP5ME mRNA CTD PMID:19244175 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 decreases expression ISO Vitamin E results in decreased expression of ATP6AP2 mRNA CTD PMID:19244175 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 increases expression ISO Vitamin E results in increased expression of ATP6V0D1 mRNA CTD PMID:19244175 NCBI chr19:37,481,782...37,525,762
Ensembl chr19:37,481,782...37,525,762
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 decreases expression ISO Vitamin E results in decreased expression of ATP6V1C1 mRNA CTD PMID:19244175 NCBI chr 7:77,678,853...77,716,658
Ensembl chr 7:77,678,968...77,716,408
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 decreases expression ISO Vitamin E results in decreased expression of ATP8B1 mRNA CTD PMID:19244175 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression
multiple interactions
ISO Vitamin E results in decreased expression of ATRX mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA
CTD PMID:19244175 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Vitamin E results in decreased expression of ATXN3 mRNA CTD PMID:19244175 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Atxn7 ataxin 7 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of ATXN7 mRNA
Vitamin E results in decreased expression of ATXN7 mRNA
CTD PMID:19244175 NCBI chr15:12,421,432...12,569,649
Ensembl chr15:12,425,175...12,513,931
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 decreases expression ISO Vitamin E results in decreased expression of AUTS2 mRNA CTD PMID:19244175 NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO Vitamin E results in decreased expression of AXL mRNA CTD PMID:19244175 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression EXP Vitamin E results in increased expression of BAAT mRNA CTD PMID:28923436 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 increases expression ISO Vitamin E results in increased expression of BABAM1 mRNA CTD PMID:19244175 NCBI chr16:19,792,720...19,798,886
Ensembl chr16:19,792,838...19,798,894
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO Vitamin E results in increased expression of BABAM2 mRNA CTD PMID:19244175 NCBI chr 6:25,666,654...26,135,888
Ensembl chr 6:25,666,655...26,051,229
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA] CTD PMID:19196431 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP alpha-Tocopherol results in increased expression of BAD mRNA CTD PMID:26332274 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO Vitamin E results in decreased expression of BAG5 mRNA CTD PMID:19244175 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Bag6 BAG cochaperone 6 increases expression ISO Vitamin E results in increased expression of BAG6 mRNA CTD PMID:19244175 NCBI chr20:5,124,512...5,138,084
Ensembl chr20:5,125,349...5,138,084
JBrowse link
G Banf1 BAF nuclear assembly factor 1 increases expression ISO Vitamin E results in increased expression of BANF1 mRNA CTD PMID:19244175 NCBI chr 1:220,744,195...220,746,224
Ensembl chr 1:220,744,195...220,746,224
JBrowse link
G Bap1 Brca1 associated protein 1 increases expression ISO Vitamin E results in increased expression of BAP1 mRNA CTD PMID:19244175 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511
JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression ISO Vitamin E results in decreased expression of BARD1 mRNA CTD PMID:19244175 NCBI chr 9:78,297,723...78,368,777
Ensembl chr 9:78,294,834...78,369,031
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor increases expression ISO Vitamin E results in increased expression of BATF mRNA CTD PMID:19244175 NCBI chr 6:109,562,415...109,584,541
Ensembl chr 6:109,562,587...109,584,545
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
affects expression
EXP
ISO
alpha-Tocopherol results in increased expression of BAX mRNA
[Vitamin E co-treated with Folic Acid] affects the expression of BAX protein; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased expression of BAX protein]
Vitamin E affects the expression of BAX protein
Vitamin E results in increased expression of BAX protein
alpha-Tocopherol affects the reaction [Lipopolysaccharides results in increased expression of BAX protein]; Vitamin E inhibits the reaction [cinnamic aldehyde results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of BAX protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased expression of BAX protein]
CTD PMID:11166918, PMID:11805214, PMID:15566391, PMID:16054126, PMID:16933212, PMID:22020378, PMID:23523949, PMID:26332274, PMID:27353299, PMID:30935902, PMID:32134168 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A decreases expression ISO Vitamin E results in decreased expression of BAZ1A mRNA CTD PMID:19244175 NCBI chr 6:75,793,223...75,873,854
Ensembl chr 6:75,793,960...75,874,235
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B increases expression ISO Vitamin E results in increased expression of BAZ1B mRNA CTD PMID:19244175 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Bbx BBX high mobility group box domain containing multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of BBX mRNA
Vitamin E results in decreased expression of BBX mRNA
CTD PMID:19244175 NCBI chr11:52,983,286...53,228,557
Ensembl chr11:53,081,025...53,228,716
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 increases expression ISO Vitamin E results in increased expression of BCAP31 mRNA CTD PMID:19244175 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; alpha-Tocopherol inhibits the reaction [Endosulfan results in decreased activity of BCHE protein]; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein] CTD PMID:20663516, PMID:24299906 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO Vitamin E results in decreased expression of BCL11A mRNA CTD PMID:19244175 NCBI chr14:108,826,717...108,921,197
Ensembl chr14:108,826,831...108,921,669
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions
ISO
EXP
alpha-Tocopherol analog results in decreased expression of BCL2 mRNA; alpha-Tocopherol analog results in decreased expression of BCL2 protein
Vitamin E results in increased expression of BCL2 mRNA
[Vitamin E co-treated with Folic Acid] affects the expression of BCL2 protein; alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased activity of BCL2 protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased expression of BCL2 protein]
[Vitamin E co-treated with Curcumin] results in decreased expression of BCL2 protein; alpha-Tocopherol affects the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; DDIT3 mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; salubrinal inhibits the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; TNFRSF10B mRNA affects the reaction [alpha-Tocopherol analog results in decreased expression of BCL2 protein]; Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BCL2 protein]
CTD PMID:11805214, PMID:15566391, PMID:16005924, PMID:16135673, PMID:16933212, PMID:20686688, PMID:22020378, PMID:27353299, PMID:30935902 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression
multiple interactions
EXP
ISO
alpha-Tocopherol results in decreased expression of BCL2L1 protein
Vitamin E results in increased expression of BCL2L1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BCL2L1 mRNA
CTD PMID:11444866, PMID:18942769, PMID:19244175 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Vitamin E results in decreased expression of BCL6 mRNA CTD PMID:19244175 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression
multiple interactions
ISO Vitamin E results in decreased expression of BCLAF1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of BCLAF1 mRNA
CTD PMID:19244175 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions EXP Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]] CTD PMID:9526112 NCBI chr19:49,637,059...49,673,577
Ensembl chr19:49,637,016...49,673,808
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in decreased expression of BDNF protein] CTD PMID:30776390 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
EXP Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 mRNA]; Vitamin E inhibits the reaction [Pilocarpine results in increased expression of BECN1 protein]
Vitamin E results in decreased expression of BECN1 protein
CTD PMID:19138675 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression
multiple interactions
ISO Vitamin E results in decreased expression of BICD1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of BICD1 mRNA
CTD PMID:19244175 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G Bicd2 BICD cargo adaptor 2 decreases expression ISO Vitamin E results in decreased expression of BICD2 mRNA CTD PMID:19244175 NCBI chr17:15,673,649...15,718,035
Ensembl chr17:15,673,650...15,718,035
JBrowse link
G Bin1 bridging integrator 1 increases expression ISO Vitamin E results in increased expression of BIN1 mRNA CTD PMID:19244175 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions EXP
ISO
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNA
Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BIRC2 protein]
CTD PMID:11444866, PMID:15566391 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO Vitamin E inhibits the reaction [cinnamic aldehyde results in decreased expression of BIRC3 protein] CTD PMID:15566391 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Vitamin E inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein] CTD PMID:24664296 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bles03 basophilic leukemia expressed protein BLES03 increases expression ISO Vitamin E results in increased expression of C11ORF68 mRNA CTD PMID:19244175 NCBI chr 1:220,806,563...220,808,817
Ensembl chr 1:220,806,473...220,808,804
JBrowse link
G Blvra biliverdin reductase A increases expression ISO Vitamin E results in increased expression of BLVRA mRNA CTD PMID:19244175 NCBI chr 3:119,552,550...119,577,796
Ensembl chr 3:119,561,290...119,577,806
JBrowse link
G Bmp2k BMP-2 inducible kinase decreases expression ISO Vitamin E results in decreased expression of BMP2K mRNA CTD PMID:19244175 NCBI chr14:14,126,086...14,226,823
Ensembl chr14:14,129,725...14,192,048
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO Vitamin E results in increased expression of BMP4 mRNA CTD PMID:19244175 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bptf bromodomain PHD finger transcription factor multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of BPTF mRNA
Vitamin E results in decreased expression of BPTF mRNA
CTD PMID:19244175 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Brd2 bromodomain containing 2 multiple interactions
decreases expression
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA
Vitamin E results in decreased expression of BRD2 mRNA
Vitamin E results in increased expression of BRD2 mRNA
CTD PMID:19244175 NCBI chr20:3,910,555...3,921,074
Ensembl chr20:3,910,555...3,917,426
Ensembl chr20:3,910,555...3,917,426
JBrowse link
G Brf2 BRF2, RNA polymerase III transcription initiation factor subunit increases expression ISO Vitamin E results in increased expression of BRF2 mRNA CTD PMID:19244175 NCBI chr16:69,089,955...69,094,678
Ensembl chr16:69,089,955...69,094,680
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator increases expression ISO Vitamin E results in increased expression of BRMS1 mRNA CTD PMID:19244175 NCBI chr 1:220,325,352...220,334,616 JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of BSCL2 mRNA
Vitamin E results in increased expression of BSCL2 mRNA
CTD PMID:19244175 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Vitamin E results in increased expression of BST2 mRNA CTD PMID:19244175 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G C1s complement C1s increases expression ISO Vitamin E results in increased expression of C1S mRNA CTD PMID:19244175 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions EXP [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CA3 mRNA CTD PMID:11444866 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO Vitamin E results in decreased expression of CAAP1 mRNA CTD PMID:19244175 NCBI chr 5:113,479,416...113,532,961
Ensembl chr 5:113,480,547...113,532,878
JBrowse link
G Cab39 calcium binding protein 39 increases expression ISO Vitamin E results in increased expression of MO25 mRNA CTD PMID:19244175 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cald1 caldesmon 1 decreases expression ISO Vitamin E results in decreased expression of CALD1 mRNA CTD PMID:19244175 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Calm3 calmodulin 3 increases expression ISO Vitamin E results in increased expression of CALM3 mRNA CTD PMID:19244175 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Calr calreticulin multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CALR mRNA
Vitamin E results in decreased expression of CALR mRNA
CTD PMID:19244175 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calu calumenin multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CALU mRNA
Vitamin E results in increased expression of CALU mRNA
CTD PMID:19244175 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO Vitamin E results in increased expression of CAMK2B mRNA CTD PMID:19244175 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma decreases expression ISO Vitamin E results in decreased expression of CAMK2G mRNA CTD PMID:19244175 NCBI chr15:3,936,721...3,995,740
Ensembl chr15:3,936,786...3,995,915
JBrowse link
G Canx calnexin affects localization
increases expression
EXP alpha-Tocopherol affects the localization of CANX protein
alpha-Tocopherol results in increased expression of CANX mRNA; alpha-Tocopherol results in increased expression of CANX protein
CTD PMID:16908007 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 increases expression ISO Vitamin E results in increased expression of CAP1 mRNA CTD PMID:19244175 NCBI chr 5:140,559,195...140,585,494
Ensembl chr 5:140,559,206...140,585,408
JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO Vitamin E results in increased expression of CAPG mRNA CTD PMID:19244175 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Capn7 calpain 7 decreases expression ISO Vitamin E results in decreased expression of CAPN7 mRNA CTD PMID:19244175 NCBI chr16:7,435,541...7,472,483
Ensembl chr16:7,435,634...7,471,807
JBrowse link
G Capns1 calpain, small subunit 1 increases expression ISO Vitamin E results in increased expression of CAPNS1 mRNA CTD PMID:19244175 NCBI chr 1:91,058,528...91,064,880 JBrowse link
G Caprin2 caprin family member 2 decreases expression ISO Vitamin E results in decreased expression of CAPRIN2 mRNA CTD PMID:19244175 NCBI chr 4:183,304,993...183,374,195
Ensembl chr 4:183,305,813...183,374,195
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta increases expression ISO Vitamin E results in increased expression of CAPZB mRNA CTD PMID:19244175 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Casc3 CASC3 exon junction complex subunit multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of MLN51 mRNA
Vitamin E results in increased expression of MLN51 mRNA
CTD PMID:19244175 NCBI chr10:86,724,534...86,744,485
Ensembl chr10:86,724,427...86,745,927
JBrowse link
G Casp3 caspase 3 decreases activity
multiple interactions
ISO
EXP
alpha-Tocopherol results in decreased activity of CASP3 protein
[alpha-Tocopherol co-treated with Nimodipine] inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased cleavage of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; Vitamin E inhibits the reaction [titanium dioxide results in increased activity of CASP3 protein]
[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; alpha-Tocopherol inhibits the reaction [Diclofenac results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Mercuric Chloride results in increased expression of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3]; Vitamin E inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]
[alpha-Tocopherol co-treated with beta-ionone] results in increased activity of CASP3 protein; [alpha-Tocopherol co-treated with Tretinoin] results in increased activity of CASP3 protein; alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Acetaldehyde results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP3 protein]; alpha-Tocopherol inhibits the reaction [Vitamin A results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP3 protein; Vitamin E inhibits the reaction [cinnamic aldehyde results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; Vitamin E inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased activity of CASP3 protein]
CTD PMID:12117551, PMID:12450566, PMID:14599462, PMID:14722101, PMID:15095415, PMID:15566391, PMID:16054126, PMID:16973328, PMID:17618090, PMID:17874176, PMID:17936189, PMID:21628957, PMID:21869839, PMID:21873648, PMID:22020378, PMID:22389237, PMID:23042730, PMID:23523949, PMID:27353299, PMID:28237877, PMID:29065513, PMID:29129777, PMID:30626778, PMID:30776390, PMID:30935902, PMID:31712109, PMID:32134168 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO alpha-Tocopherol inhibits the reaction [S-(1,2-dichlorovinyl)cysteine results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]] CTD PMID:23042730, PMID:29129777 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases cleavage ISO alpha-Tocopherol analog results in increased cleavage of CASP8 protein CTD PMID:20686688 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol analog results in increased cleavage of CASP9 protein
alpha-Tocopherol inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Vitamin E inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]
Vitamin E results in increased expression of CASP9 mRNA
alpha-Tocopherol results in increased cleavage of and results in increased activity of CASP9 protein
CTD PMID:16973328, PMID:19244175, PMID:20686688, PMID:21628957, PMID:21869839, PMID:27353299, PMID:31712109 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
multiple interactions
decreases activity
affects expression
increases activity
ISO
EXP
alpha-Tocopherol results in increased expression of CAT mRNA; alpha-Tocopherol results in increased expression of CAT protein
alpha-Tocopherol results in increased expression of CAT protein; Vitamin E results in increased expression of CAT protein
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; [Vitamin E co-treated with coenzyme Q10] results in increased activity of CAT protein; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; [Vitamin E co-treated with Quercetin] inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; [Vitamin E co-treated with Sodium Selenite] inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; [Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]] which affects the abundance of Reactive Oxygen Species; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; alpha-Tocopherol affects the reaction [Copper Sulfate results in decreased activity of CAT protein]; alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Ginkgo biloba extract promotes the reaction [Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Carbofuran results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Food Additives affects the activity of CAT protein]; Vitamin E inhibits the reaction [Formaldehyde results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Methoxychlor results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Nanotubes, Carbon results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Petroleum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of CAT protein]; Vitamin E promotes the reaction [Ginkgo biloba extract inhibits the reaction [endotoxin, Escherichia coli results in decreased activity of CAT protein]]
Vitamin E results in decreased activity of CAT protein
[Vitamin E co-treated with coenzyme Q10] inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [fipronil results in decreased activity of CAT protein]
Vitamin E affects the expression of CAT protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; Vitamin E inhibits the reaction [Aluminum results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]
alpha-Tocopherol results in increased activity of CAT protein
CTD PMID:9306888, PMID:11597945, PMID:11834209, PMID:11955947, PMID:12355564, PMID:14535831, PMID:15669049, PMID:15820619, PMID:16144695, PMID:16298753, PMID:16758767, PMID:16937016, PMID:16979807, PMID:17262218, PMID:17383094, PMID:17709913, PMID:17927767, PMID:18547560, PMID:18655177, PMID:19083475, PMID:19464315, PMID:19914224, PMID:19941068, PMID:19958828, PMID:20077558, PMID:20079796, PMID:20194575, PMID:20535553, PMID:21086752, PMID:21322096, PMID:21628957, PMID:21736874, PMID:21787585, PMID:22020378, PMID:22207723, PMID:22732938, PMID:23348005, PMID:23369933, PMID:23619517, PMID:24865641, PMID:25046308, PMID:25721553, PMID:27823922, PMID:29948670, PMID:30057697, PMID:31022331 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO alpha-Tocopherol inhibits the reaction [Lysophosphatidylcholines results in increased expression of CAV1 mRNA]
Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAV1 protein]
CTD PMID:12134086, PMID:27257344 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin1 caveolae associated protein 1 multiple interactions
increases expression
ISO Vitamin E inhibits the reaction [Hydrogen Peroxide results in increased expression of CAVIN1 protein]
Vitamin E results in increased expression of CAVIN1 mRNA
CTD PMID:19244175, PMID:21705337 NCBI chr10:88,862,513...88,874,495
Ensembl chr10:88,860,733...88,874,528
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression ISO Vitamin E results in increased expression of CAVIN3 mRNA CTD PMID:19244175 NCBI chr 1:170,317,099...170,318,688
Ensembl chr 1:170,317,113...170,318,935
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO Vitamin E results in decreased expression of CBLB mRNA CTD PMID:19244175 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Cbx5 chromobox 5 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CBX5 mRNA
Vitamin E results in decreased expression of CBX5 mRNA
CTD PMID:19244175 NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
JBrowse link
G Cbx6 chromobox 6 increases expression ISO Vitamin E results in increased expression of CBX6 mRNA CTD PMID:19244175 NCBI chr 7:121,047,996...121,058,109
Ensembl chr 7:121,050,302...121,058,029
JBrowse link
G Cbx7 chromobox 7 increases expression ISO Vitamin E results in increased expression of CBX7 mRNA CTD PMID:19244175 NCBI chr 7:121,136,067...121,153,503
Ensembl chr 7:121,136,058...121,153,383
JBrowse link
G Cby1 chibby family member 1, beta catenin antagonist increases expression ISO Vitamin E results in increased expression of CBY1 mRNA CTD PMID:19244175 NCBI chr 7:120,891,930...120,898,318
Ensembl chr 7:120,891,940...120,897,687
JBrowse link
G Ccdc85b coiled-coil domain containing 85B multiple interactions
increases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of DIPA mRNA
Vitamin E results in increased expression of DIPA mRNA
CTD PMID:19244175 NCBI chr 1:220,835,647...220,837,220 JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 increases expression ISO Vitamin E results in increased expression of CCHCR1 mRNA CTD PMID:19244175 NCBI chr20:3,730,968...3,745,721
Ensembl chr20:3,730,955...3,740,009
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO
EXP
alpha-Tocopherol inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein]
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; alpha-Tocopherol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD PMID:19735175, PMID:24333275, PMID:26332274 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNA CTD PMID:16797527 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
affects expression
ISO
EXP
Vitamin E results in increased expression of CCND1 mRNA
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]
Vitamin E affects the expression of CCND1 mRNA; Vitamin E affects the expression of CCND1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CCND1 mRNA; alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA]
CTD PMID:11444866, PMID:16298738, PMID:19244175, PMID:26332274, PMID:30935902 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
increases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA]
Vitamin E results in increased expression of CCND2 mRNA
CTD PMID:19244175, PMID:26332274 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 affects expression EXP Vitamin E affects the expression of CCND3 mRNA CTD PMID:15370891 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 affects expression EXP Vitamin E affects the expression of CCNE1 mRNA CTD PMID:16298738 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccnl1 cyclin L1 decreases expression ISO Vitamin E results in decreased expression of CCNL1 mRNA CTD PMID:19244175 NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838
JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression ISO Vitamin E results in decreased expression of CPR8 mRNA CTD PMID:19244175 NCBI chr 8:79,660,634...79,692,044
Ensembl chr 8:79,660,657...79,692,039
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Vitamin E results in increased expression of CCS mRNA CTD PMID:19244175 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 increases expression ISO Vitamin E results in increased expression of CD2BP2 mRNA CTD PMID:19244175 NCBI chr 1:198,635,445...198,641,195
Ensembl chr 1:198,635,447...198,638,944
JBrowse link
G Cd36 CD36 molecule affects expression
multiple interactions
EXP alpha-Tocopherol affects the expression of CD36 mRNA
alpha-Tocopherol inhibits the reaction [[troglitazone co-treated with Ethanol] results in increased expression of CD36 protein]
CTD PMID:16407258 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Vitamin E results in decreased expression of CD44 mRNA CTD PMID:19244175 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd63 Cd63 molecule increases expression ISO Vitamin E results in increased expression of CD63 mRNA CTD PMID:19244175 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Vitamin E inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Ethylmercuric Chloride results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Thimerosal results in increased expression of CD86 protein] CTD PMID:20457211 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cd99 CD99 molecule (Xg blood group) increases expression ISO Vitamin E results in increased expression of CD99 mRNA CTD PMID:19244175 NCBI chr20:56,192,426...56,196,961
Ensembl chr20:56,192,390...56,197,025
JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Vitamin E results in decreased expression of CDC14B mRNA CTD PMID:19244175 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750
JBrowse link
G Cdc16 cell division cycle 16 decreases expression ISO Vitamin E results in decreased expression of CDC16 mRNA CTD PMID:19244175 NCBI chr16:81,493,355...81,516,493
Ensembl chr16:81,493,355...81,516,493
JBrowse link
G Cdc25b cell division cycle 25B increases expression ISO Vitamin E results in increased expression of CDC25B mRNA CTD PMID:19244175 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc27 cell division cycle 27 decreases expression ISO Vitamin E results in decreased expression of CDC27 mRNA CTD PMID:19244175 NCBI chr10:92,551,754...92,602,214
Ensembl chr10:92,554,081...92,602,082
JBrowse link
G Cdc42bpa CDC42 binding protein kinase alpha multiple interactions
increases expression
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CDC42BPA mRNA
Vitamin E results in increased expression of CDC42BPA mRNA
Vitamin E results in decreased expression of CDC42BPA mRNA
CTD PMID:19244175 NCBI chr13:98,231,326...98,447,762
Ensembl chr13:98,231,326...98,447,762
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein] CTD PMID:29940330 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh3 cadherin 3 increases expression ISO Vitamin E results in increased expression of CDH3 mRNA CTD PMID:19244175 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdk10 cyclin-dependent kinase 10 multiple interactions ISO [Selenium co-treated with Vitamin E] results in decreased expression of CDK10 mRNA CTD PMID:19244175 NCBI chr19:56,024,903...56,032,610
Ensembl chr19:56,024,903...56,032,605
JBrowse link
G Cdk13 cyclin-dependent kinase 13 decreases expression ISO Vitamin E results in decreased expression of CDK13 mRNA CTD PMID:19244175 NCBI chr17:49,833,194...49,922,932
Ensembl chr17:49,833,400...49,921,550
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO Vitamin E results in increased expression of CDK4 mRNA CTD PMID:19244175 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects expression
decreases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]
Vitamin E inhibits the reaction [Curcumin results in decreased expression of CDKN1A protein]
Vitamin E affects the expression of CDKN1A mRNA
alpha-Tocopherol results in decreased expression of CDKN1A mRNA
CTD PMID:16298738, PMID:26332274, PMID:30935902 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Vitamin E results in increased expression of CDKN1B protein CTD PMID:12352461 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 decreases expression ISO Vitamin E results in decreased expression of CDS1 mRNA CTD PMID:19244175 NCBI chr14:9,396,511...9,456,964
Ensembl chr14:9,396,512...9,456,990
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Vitamin E inhibits the reaction [Ethanol results in decreased activity of CEBPA protein]; Vitamin E inhibits the reaction [Ethanol results in decreased expression of CEBPA protein] CTD PMID:16737972 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases response to substance ISO CEBPB results in increased susceptibility to Vitamin E CTD PMID:9359698 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cep164 centrosomal protein 164 increases expression ISO Vitamin E results in increased expression of CEP164 mRNA CTD PMID:19244175 NCBI chr 8:50,069,282...50,132,477
Ensembl chr 8:50,070,579...50,126,413
JBrowse link
G Cep170 centrosomal protein 170 decreases expression ISO Vitamin E results in decreased expression of CEP170 mRNA CTD PMID:19244175 NCBI chr13:94,807,090...94,887,448
Ensembl chr13:94,807,756...94,859,436
JBrowse link
G Cep290 centrosomal protein 290 decreases expression ISO Vitamin E results in decreased expression of CEP290 mRNA CTD PMID:19244175 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327
JBrowse link
G Cep350 centrosomal protein 350 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNA
Vitamin E results in decreased expression of CEP350 mRNA
CTD PMID:19244175 NCBI chr13:73,499,715...73,637,707
Ensembl chr13:73,499,229...73,638,073
JBrowse link
G Cep57 centrosomal protein 57 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in decreased expression of CEP57 mRNA
Vitamin E results in decreased expression of CEP57 mRNA
CTD PMID:19244175 NCBI chr 8:12,335,430...12,355,425
Ensembl chr 8:12,335,432...12,355,091
JBrowse link
G Cep97 centrosomal protein 97 decreases expression ISO Vitamin E results in decreased expression of CEP97 mRNA CTD PMID:19244175 NCBI chr11:47,146,409...47,174,460
Ensembl chr11:47,146,308...47,174,713
JBrowse link
G Cerk ceramide kinase increases expression ISO Vitamin E results in increased expression of CERK mRNA CTD PMID:19244175 NCBI chr 7:127,015,162...127,058,056
Ensembl chr 7:127,015,162...127,058,056
JBrowse link
G Cert1 ceramide transporter 1 multiple interactions
decreases expression
ISO [Selenium co-treated with Vitamin E] results in increased expression of CERT1 mRNA
Vitamin E results in decreased expression of CERT1 mRNA
CTD PMID:19244175 NCBI chr 2:27,365,145...27,469,797
Ensembl chr 2:27,365,148...27,469,779
JBrowse link