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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:21-dehydrocortisol
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Accession:CHEBI:78595 term browser browse the term
Definition:A C21-steroid that is cortisol in which the 21-hydroxy group has been oxidised to the corresponding aldehyde.
Synonyms:exact_synonym: (11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-al
 related_synonym: 11beta,17-dihydroxy-21-oxoprogesterone;   11beta,17alpha-dihydroxypregn-4-en-3,20-dione-21-al;   11beta,17alpha-dihydroxypregn-4-ene-3,20,21-trione;   4-pregnen-11beta,17alpha-diol-3,20-dione-21-al;   Formula=C21H28O5;   InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,11,14-16,18,24,26H,3-8,10H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1;   InChIKey=JIELFMXLFHFDRT-VWUMJDOOSA-N;   SMILES=C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)C=O
 xref: CAS:14760-49-7
 xref_mesh: MESH:C026547
 xref: PMID:1112882;   PMID:170263;   PMID:171488;   PMID:5413721;   PMID:5685579;   PMID:7098476;   PMID:7439163;   Reaxys:4564511



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21-dehydrocortisol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 21-dehydrocortisol CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      group 19986
        organic group 18961
          3-oxo-Delta(4)-steroid group 9160
            3-oxo-Delta(4) steroid 9160
              21-dehydrocortisol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic acid 18594
                                        carboacyl group 17706
                                          univalent carboacyl group 17706
                                            formyl group 8800
                                              aldehyde 8800
                                                steroid aldehyde 92
                                                  21-dehydrocortisol 1
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