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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aflatoxin Q1
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Accession:CHEBI:78582 term browser browse the term
Definition:A member of the class of aflatoxins that is aflatoxin B1 in which the hydrogen at the pro-3S position is replaced by a hydroxy group.
Synonyms:exact_synonym: (3S,6aR,9aS)-3-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione
 related_synonym: AFQ1;   Formula=C17H12O7;   InChI=1S/C17H12O7/c1-21-9-5-10-11(6-2-3-22-17(6)23-10)15-14(9)12-7(18)4-8(19)13(12)16(20)24-15/h2-3,5-7,17-18H,4H2,1H3/t6-,7-,17+/m0/s1;   InChIKey=GYNOTJLCULOEIM-XKRJZGAWSA-N;   SMILES=COc1cc2O[C@H]3OC=C[C@H]3c2c2oc(=O)c3C(=O)C[C@H](O)c3c12
 xref: CAS:52819-96-2;   HMDB:HMDB0030753;   KEGG:C19585;   KNApSAcK:C00023624
 xref_mesh: MESH:C033759
 xref: PMID:1185319;   PMID:1643250;   PMID:3099349;   PMID:3116726;   PMID:3141079;   PMID:4081304;   PMID:6622820;   PMID:6712219;   PMID:6766512;   PMID:7987484;   PMID:9385444;   Reaxys:8866397



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aflatoxin Q1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin Q1 CTD PMID:20707407 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G Gnmt glycine N-methyltransferase decreases secretion ISO GNMT results in decreased secretion of aflatoxin Q1 CTD PMID:19146867 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      biological role 19746
        aetiopathogenetic role 19022
          carcinogenic agent 18359
            aflatoxin Q1 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic molecule 19545
                              organic cyclic compound 19339
                                organic heterocyclic compound 18579
                                  organic heteropolycyclic compound 18039
                                    organic heteropentacyclic compound 13307
                                      cyclopentafurofurochromene 11075
                                        aflatoxin 11075
                                          aflatoxin B1 11075
                                            aflatoxin Q1 2
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