Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:78549 term browser browse the term
Definition:A member of the class of bipiperidines that is 1,4'-bipiperidine which is substituted at the 1' and 4' positions by 4-(p-fluorophenyl)-4-oxobutyl and carboxamide groups, respectively. A first generation antipsychotic, its properties are generally similar to those of haloperidol.
Synonyms:exact_synonym: 1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide
 related_synonym: 1'-(3-(p-fluorobenzoyl)propyl)-(1,4'-bipiperidine)-4'-carboxamide;   Formula=C21H30FN3O2;   InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27);   InChIKey=AXKPFOAXAHJUAG-UHFFFAOYSA-N;   R 3345;   SMILES=NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1;   floropipamide;   p-fluoro-gamma-(4-piperidino-4-carbamoylpiperidino)butyrophenone;   pipamperona;   pipamperonum
 xref: CAS:1893-33-0 "ChemIDplus";   CAS:1893-33-0 "NIST Chemistry WebBook";   Drug_Central:2181 "DrugCentral";   KEGG:D02622;   LINCS:LSM-2586;   PMID:1359893 "Europe PMC";   PMID:21349239 "Europe PMC";   PMID:24614672 "Europe PMC";   PMID:610354 "Europe PMC";   Patent:BE610830;   Reaxys:496532 "Reaxys";   Wikipedia:Pipamperone
 cyclic_relationship: is_conjugate_base_of CHEBI:78943

show annotations for term's descendants       view all columns           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        pharmacological role 18687
          neurotransmitter agent 16229
            serotonergic drug 3855
              serotonergic antagonist 2227
                pipamperone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic acid 17921
                                        carboacyl group 16944
                                          univalent carboacyl group 16944
                                            carbamoyl group 16623
                                              carboxamide 16623
                                                monocarboxylic acid amide 13187
                                                  pipamperone 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.