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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxycodone
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Accession:CHEBI:7852 term browser browse the term
Definition:A semisynthetic opioid of formula C18H21NO4 that is derived from thebaine. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain.
Synonyms:exact_synonym: 14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one
 related_synonym: (-)-14-Hydroxydihydrocodeinone;   4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;   4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one;   Dihydro-14-hydroxycodeinone;   Dihydrohydroxycodeinone;   Dihydroxycodeinone;   Formula=C18H21NO4;   InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1;   InChIKey=BRUQQQPBMZOVGD-XFKAJCMBSA-N;   SMILES=COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O;   oxicodona;   oxycodonum
 xref: Beilstein:43446;   CAS:76-42-6;   DrugBank:DB00497;   Drug_Central:2029;   KEGG:C08018;   KEGG:D05312
 xref_mesh: MESH:D010098
 xref: PMID:27093887;   PMID:27873179;   PMID:27921252;   PMID:28074831;   PMID:28080998;   PMID:28107783;   PMID:28127624;   PMID:28170358;   PMID:28194654;   PMID:28205004;   Wikipedia:Oxycodone
 cyclic_relationship: is_conjugate_base_of CHEBI:134686


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oxycodone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 increases expression EXP Oxycodone results in increased expression of ABCA8 mRNA CTD PMID:23439660 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Oxycodone results in increased expression of ABCB1A mRNA; Oxycodone results in increased expression of ABCB1A protein CTD PMID:23439660 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Oxycodone results in increased expression of ABCB4 mRNA CTD PMID:23439660 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression EXP Oxycodone results in decreased expression of ABCG1 mRNA CTD PMID:23439660 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Oxycodone results in increased expression of ABCG5 mRNA CTD PMID:23439660 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase increases expression EXP Oxycodone results in increased expression of ABHD6 mRNA CTD PMID:23439660 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression EXP Oxycodone results in increased expression of ACSM2A mRNA CTD PMID:23439660 NCBI chr 1:189,289,957...189,329,007
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Oxycodone results in decreased expression of ACTN1 mRNA CTD PMID:23439660 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression EXP Oxycodone results in decreased expression of ADAM17 mRNA CTD PMID:23439660 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression EXP Oxycodone results in increased expression of ADAMTS1 mRNA CTD PMID:23439660 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression EXP Oxycodone results in decreased expression of ADGRE1 mRNA CTD PMID:23439660 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression EXP Oxycodone results in increased expression of AHR mRNA CTD PMID:23439660 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression EXP Oxycodone results in decreased expression of AKR1C3 mRNA CTD PMID:23439660 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Oxycodone results in decreased expression of ANXA3 mRNA CTD PMID:23439660 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression EXP Oxycodone results in decreased expression of ARHGDIB mRNA CTD PMID:23439660 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Asl argininosuccinate lyase increases expression EXP Oxycodone results in increased expression of ASL mRNA CTD PMID:23439660 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO
EXP
Oxycodone results in increased expression of ATF4 protein CTD PMID:26377394 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Oxycodone results in increased expression of ATP1B1 mRNA CTD PMID:23439660 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 increases expression EXP Oxycodone results in increased expression of B4GALNT1 mRNA CTD PMID:23439660 NCBI chr 7:70,439,273...70,459,556
Ensembl chr 7:70,452,579...70,459,880
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression EXP Oxycodone results in decreased expression of BCL2A1 mRNA CTD PMID:23439660 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Blvra biliverdin reductase A decreases expression EXP Oxycodone results in decreased expression of BLVRA mRNA CTD PMID:23439660 NCBI chr 3:119,552,550...119,577,796
Ensembl chr 3:119,561,290...119,577,806
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP Oxycodone results in decreased expression of CA3 mRNA CTD PMID:23439660 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cav2 caveolin 2 decreases expression EXP Oxycodone results in decreased expression of CAV2 mRNA CTD PMID:23439660 NCBI chr 4:44,573,264...44,580,640
Ensembl chr 4:44,573,264...44,580,638
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression EXP Oxycodone results in decreased expression of CCL6 mRNA CTD PMID:23439660 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Cd5l Cd5 molecule-like decreases expression EXP Oxycodone results in decreased expression of CD5L mRNA CTD PMID:23439660 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Oxycodone results in increased expression of CDKN1A mRNA CTD PMID:23439660 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ces2h carboxylesterase 2H affects expression
increases expression
EXP Oxycodone affects the expression of CES2 mRNA
Oxycodone results in increased expression of CES2 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression EXP Oxycodone results in increased expression of CHD1L mRNA CTD PMID:23439660 NCBI chr 2:199,714,044...199,792,270
Ensembl chr 2:199,716,713...199,771,896
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 decreases expression EXP Oxycodone results in decreased expression of CMTM6 mRNA CTD PMID:23439660 NCBI chr 8:122,789,208...122,807,560
Ensembl chr 8:122,789,453...122,807,560
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP Oxycodone results in decreased expression of CNP1 mRNA CTD PMID:23439660 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression EXP Oxycodone results in decreased expression of COTL1 mRNA CTD PMID:23439660 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP Oxycodone results in decreased expression of CSRP1 mRNA CTD PMID:23439660 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Ctsc cathepsin C decreases expression EXP Oxycodone results in decreased expression of CTSC mRNA CTD PMID:23439660 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsl cathepsin L increases expression EXP Oxycodone results in increased expression of CTSL mRNA CTD PMID:23439660 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression EXP Oxycodone results in decreased expression of CYBA mRNA CTD PMID:23439660 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression
increases expression
EXP Oxycodone affects the expression of CYP17A1 mRNA
Oxycodone results in increased expression of CYP17A1 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP27A1 mRNA CTD PMID:23439660 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP2A1 mRNA CTD PMID:23439660 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression
increases expression
EXP Oxycodone affects the expression of CYP2B2 mRNA
Oxycodone results in increased expression of CYP2B2 mRNA; Oxycodone results in increased expression of CYP2B2 protein
CTD PMID:20487198 PMID:23439660 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Oxycodone results in decreased expression of CYP2C11 mRNA; Oxycodone results in decreased expression of CYP2C9 mRNA CTD PMID:23439660 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 affects expression
decreases expression
EXP Oxycodone affects the expression of CYP2C13 mRNA
Oxycodone results in decreased expression of CYP2C13 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance
multiple interactions
ISO CYP2D6 gene polymorphism affects the susceptibility to Oxycodone
[Quinidine results in decreased activity of CYP2D6 protein] which affects the susceptibility to Oxycodone
CTD PMID:20590588 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP2E1 mRNA CTD PMID:23439660 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Oxycodone results in increased expression of CYP2J4 mRNA CTD PMID:23439660 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases expression
EXP Oxycodone inhibits the reaction [CYP3A2 protein results in increased hydroxylation of Testosterone]
Oxycodone results in decreased expression of CYP3A2 mRNA; Oxycodone results in decreased expression of CYP3A2 protein
CTD PMID:20487198 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP3A23-3A1 mRNA; Oxycodone results in increased expression of CYP3A23-3A1 protein CTD PMID:23439660 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO telithromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Oxycodone] CTD PMID:19755414 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Oxycodone results in increased expression of CYP4B1 mRNA CTD PMID:23439660 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 increases expression EXP Oxycodone results in increased expression of DBT mRNA CTD PMID:23439660 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP Oxycodone results in increased expression of EHHADH mRNA CTD PMID:23439660 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO
EXP
Naloxone inhibits the reaction [Oxycodone results in increased phosphorylation of EIF2S1 protein] CTD PMID:26377394 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression EXP Oxycodone results in increased expression of ELL2 mRNA CTD PMID:23439660 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression EXP Oxycodone affects the expression of EPHX2 mRNA CTD PMID:20487198 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Exosc5 exosome component 5 increases expression EXP Oxycodone results in increased expression of EXOSC5 mRNA CTD PMID:23439660 NCBI chr 1:82,452,104...82,461,607
Ensembl chr 1:82,452,469...82,461,606
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa decreases expression EXP Oxycodone results in decreased expression of FCGR2A mRNA CTD PMID:23439660 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Oxycodone results in increased expression of FKBP5 mRNA CTD PMID:23439660 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression
increases expression
EXP Oxycodone affects the expression of FMO1 mRNA
Oxycodone results in increased expression of FMO1 mRNA
CTD PMID:20487198 PMID:23439660 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Oxycodone results in increased expression of FOS protein CTD PMID:26377394 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Oxycodone results in increased expression of GPAM mRNA CTD PMID:23439660 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP Oxycodone results in increased expression of GPT mRNA CTD PMID:23439660 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression EXP Oxycodone results in increased expression of GPT2 mRNA CTD PMID:23439660 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP Oxycodone results in increased expression of GSTA3 mRNA CTD PMID:23439660 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP Oxycodone results in increased expression of GSTA5 mRNA; Oxycodone results in increased expression of GSTA5 protein CTD PMID:20487198 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP Oxycodone results in increased expression of HPCL2 mRNA CTD PMID:23439660 NCBI chr16:7,720,047...7,758,119
Ensembl chr16:7,714,465...7,758,189
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP Oxycodone results in decreased expression of HAO2 mRNA CTD PMID:23439660 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase decreases expression EXP Oxycodone results in decreased expression of HCK mRNA CTD PMID:23439660 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
JBrowse link
G Hexb hexosaminidase subunit beta increases expression EXP Oxycodone results in increased expression of HEXB mRNA CTD PMID:23439660 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression EXP Oxycodone results in increased expression of HNRNPAB mRNA CTD PMID:23439660 NCBI chr10:34,955,713...34,961,662
Ensembl chr10:34,955,716...34,961,608
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Oxycodone results in increased expression of HOMER1 mRNA CTD PMID:23439660 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP Oxycodone results in decreased expression of HSD11B1 mRNA CTD PMID:23439660 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO
EXP
Oxycodone results in increased expression of HSPA5 protein CTD PMID:26377394 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP Oxycodone results in decreased expression of IGFALS mRNA CTD PMID:23439660 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP Oxycodone results in increased expression of IGFBP1 mRNA CTD PMID:23439660 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Il18bp interleukin 18 binding protein decreases expression EXP Oxycodone results in decreased expression of IL18BP mRNA CTD PMID:23439660 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP Oxycodone results in decreased expression of INHBE mRNA CTD PMID:23439660 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 increases expression EXP Oxycodone results in increased expression of IP6K2 mRNA CTD PMID:23439660 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression EXP Oxycodone results in decreased expression of ITGB2 mRNA CTD PMID:23439660 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression EXP Oxycodone results in increased expression of ITPR1 mRNA CTD PMID:23439660 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression EXP Oxycodone results in decreased expression of JCHAIN mRNA CTD PMID:23439660 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
JBrowse link
G Klc4 kinesin light chain 4 increases expression EXP Oxycodone results in increased expression of KLC4 mRNA CTD PMID:23439660 NCBI chr 9:16,647,577...16,661,463
Ensembl chr 9:16,647,598...16,661,464
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 decreases expression EXP Oxycodone results in decreased expression of LCP1 mRNA CTD PMID:23439660 NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
JBrowse link
G Lgals3 galectin 3 decreases expression EXP Oxycodone results in decreased expression of LGALS3 mRNA CTD PMID:23439660 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase increases expression EXP Oxycodone results in increased expression of LHPP mRNA CTD PMID:23439660 NCBI chr 1:204,617,804...204,708,987
Ensembl chr 1:204,617,852...204,708,987
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component decreases expression EXP Oxycodone results in decreased expression of LIN7A mRNA CTD PMID:23439660 NCBI chr 7:49,429,613...49,627,835
Ensembl chr 7:49,385,705...49,656,856
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression EXP Oxycodone results in decreased expression of LY86 mRNA CTD PMID:23439660 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP Oxycodone results in increased phosphorylation of MAPK1 protein CTD PMID:26377394 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP Oxycodone results in increased phosphorylation of MAPK3 protein CTD PMID:26377394 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Masp1 mannan-binding lectin serine peptidase 1 decreases expression EXP Oxycodone results in decreased expression of MASP1 mRNA CTD PMID:23439660 NCBI chr11:80,736,424...80,806,278
Ensembl chr11:80,736,576...80,803,382
JBrowse link
G Mtmr7 myotubularin related protein 7 increases expression EXP Oxycodone results in increased expression of MTMR7 mRNA CTD PMID:23439660 NCBI chr16:54,765,214...54,856,255
Ensembl chr16:54,765,325...54,856,225
JBrowse link
G Myo1b myosin Ib increases expression EXP Oxycodone results in increased expression of MYO1B mRNA CTD PMID:23439660 NCBI chr 9:54,706,005...54,766,054
Ensembl chr 9:54,558,202...54,766,054
JBrowse link
G Notch2 notch receptor 2 decreases expression EXP Oxycodone results in decreased expression of NOTCH2 mRNA CTD PMID:23439660 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression EXP Oxycodone results in increased expression of NR1I2 mRNA CTD PMID:23439660 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression EXP Oxycodone results in increased expression of NR1I3 mRNA CTD PMID:23439660 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Oxycodone results in decreased expression of NREP mRNA CTD PMID:23439660 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Oprd1 opioid receptor, delta 1 affects binding EXP Oxycodone binds to OPRD1 protein CTD PMID:7562497 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprk1 opioid receptor, kappa 1 affects binding EXP Oxycodone binds to OPRK1 protein CTD PMID:7562497 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Oprm1 opioid receptor, mu 1 affects binding EXP Oxycodone binds to OPRM1 protein CTD PMID:7562497 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Orm1 orosomucoid 1 decreases expression EXP Oxycodone results in decreased expression of ORM1 mRNA CTD PMID:23439660 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Oxycodone results in decreased expression of OSGIN1 mRNA CTD PMID:23439660 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP Oxycodone results in decreased expression of PDE4B mRNA CTD PMID:23439660 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha increases expression EXP Oxycodone results in increased expression of PDGFRA protein CTD PMID:26377394 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression EXP Oxycodone results in increased expression of PFKFB1 mRNA CTD PMID:23439660 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression EXP Oxycodone results in decreased expression of PIK3C3 mRNA CTD PMID:23439660 NCBI chr18:22,964,121...23,047,896
Ensembl chr18:22,964,210...23,047,895
JBrowse link
G Pla2g4a phospholipase A2 group IVA decreases expression EXP Oxycodone results in decreased expression of PLA2G4A mRNA CTD PMID:23439660 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pld1 phospholipase D1 decreases expression EXP Oxycodone results in decreased expression of PLD1 mRNA CTD PMID:23439660 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Plscr1 phospholipid scramblase 1 decreases expression EXP Oxycodone results in decreased expression of PLSCR1 mRNA CTD PMID:23439660 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression EXP Oxycodone results in increased expression of PNPLA7 mRNA CTD PMID:23439660 NCBI chr 3:2,182,191...2,261,890
Ensembl chr 3:2,182,957...2,261,878
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Oxycodone results in increased expression of POR mRNA CTD PMID:23439660 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression EXP Oxycodone results in decreased expression of PRKAB1 mRNA CTD PMID:23439660 NCBI chr12:46,316,298...46,326,789
Ensembl chr12:46,316,236...46,326,790
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases phosphorylation EXP Oxycodone results in increased phosphorylation of PRKACA protein CTD PMID:26377394 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prlr prolactin receptor increases expression EXP Oxycodone results in increased expression of PRLR mRNA CTD PMID:23439660 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Ptdss2 phosphatidylserine synthase 2 increases expression EXP Oxycodone results in increased expression of PTDSS2 mRNA CTD PMID:23439660 NCBI chr 1:214,122,981...214,148,011
Ensembl chr 1:214,123,044...214,149,729
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP Oxycodone results in increased expression of PTP4A1 mRNA CTD PMID:23439660 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Pxmp4 peroxisomal membrane protein 4 increases expression EXP Oxycodone results in increased expression of PXMP4 mRNA CTD PMID:23439660 NCBI chr 3:150,091,646...150,108,893
Ensembl chr 3:150,091,630...150,108,898
JBrowse link
G Pycard PYD and CARD domain containing decreases expression EXP Oxycodone results in decreased expression of PYCARD mRNA CTD PMID:23439660 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP Oxycodone results in increased expression of RAB30 mRNA CTD PMID:23439660 NCBI chr 1:157,573,344...157,667,973
Ensembl chr 1:157,573,324...157,660,008
JBrowse link
G Rab38 RAB38, member RAS oncogene family decreases expression EXP Oxycodone results in decreased expression of RAB38 mRNA CTD PMID:23439660 NCBI chr 1:152,072,716...152,153,449
Ensembl chr 1:152,072,665...152,153,449
JBrowse link
G Rac2 Rac family small GTPase 2 decreases expression EXP Oxycodone results in decreased expression of RAC2 mRNA CTD PMID:23439660 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP Oxycodone results in decreased expression of RCAN1 mRNA CTD PMID:23439660 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Serpina7 serpin family A member 7 decreases expression EXP Oxycodone results in decreased expression of SERPINA7 mRNA CTD PMID:23439660 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression EXP Oxycodone results in decreased expression of SKAP2 mRNA CTD PMID:23439660 NCBI chr 4:81,816,778...81,968,832
Ensembl chr 4:81,818,569...81,968,832
JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression EXP Oxycodone results in decreased expression of SLC10A2 mRNA CTD PMID:23439660 NCBI chr16:90,324,420...90,350,254
Ensembl chr16:90,324,361...90,345,865
JBrowse link
G Slc15a3 solute carrier family 15 member 3 decreases expression EXP Oxycodone results in decreased expression of SLC15A3 mRNA CTD PMID:23439660 NCBI chr 1:226,896,387...226,912,644
Ensembl chr 1:226,897,625...226,912,708
JBrowse link
G Slc16a1 solute carrier family 16 member 1 decreases expression EXP Oxycodone results in decreased expression of SLC16A1 mRNA CTD PMID:23439660 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP Oxycodone results in increased expression of SLC16A10 mRNA CTD PMID:23439660 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Slc17a5 solute carrier family 17 member 5 increases expression EXP Oxycodone results in increased expression of SLC17A5 mRNA CTD PMID:23439660 NCBI chr 8:85,891,245...85,926,466
Ensembl chr 8:85,891,257...85,926,450
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Oxycodone results in increased expression of SLC1A2 mRNA CTD PMID:23439660 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP Oxycodone results in increased expression of SLC22A5 mRNA CTD PMID:23439660 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases expression EXP Oxycodone results in decreased expression of SLC22A8 mRNA CTD PMID:23439660 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc25a15 solute carrier family 25 member 15 increases expression EXP Oxycodone results in increased expression of SLC25A15 mRNA CTD PMID:23439660 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529
JBrowse link
G Slc25a29 solute carrier family 25 member 29 increases expression EXP Oxycodone results in increased expression of SLC25A29 mRNA CTD PMID:23439660 NCBI chr 6:132,736,964...132,747,912
Ensembl chr 6:132,735,883...132,747,828
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP Oxycodone results in decreased expression of SLC25A30 mRNA CTD PMID:23439660 NCBI chr15:57,811,612...57,834,173
Ensembl chr15:57,813,356...57,834,173
JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression EXP Oxycodone results in increased expression of SLC27A5 mRNA CTD PMID:23439660 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP Oxycodone results in increased expression of SLC2A2 mRNA CTD PMID:23439660 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Oxycodone results in decreased expression of SLC34A2 mRNA CTD PMID:23439660 NCBI chr14:60,257,211...60,276,516
Ensembl chr14:60,256,712...60,276,794
JBrowse link
G Slc35b2 solute carrier family 35 member B2 decreases expression EXP Oxycodone results in decreased expression of SLC35B2 mRNA CTD PMID:23439660 NCBI chr 9:17,823,399...17,827,032
Ensembl chr 9:17,823,400...17,827,032
JBrowse link
G Slc37a4 solute carrier family 37 member 4 increases expression EXP Oxycodone results in increased expression of SLC37A4 mRNA CTD PMID:23439660 NCBI chr 8:48,716,914...48,723,024
Ensembl chr 8:48,716,939...48,723,024
JBrowse link
G Slc38a4 solute carrier family 38, member 4 increases expression EXP Oxycodone results in increased expression of SLC38A4 mRNA CTD PMID:23439660 NCBI chr 7:138,459,576...138,512,952
Ensembl chr 7:138,459,504...138,512,952
JBrowse link
G Slc39a4 solute carrier family 39 member 4 increases expression EXP Oxycodone results in increased expression of SLC39A4 mRNA CTD PMID:23439660 NCBI chr 7:117,675,718...117,682,586
Ensembl chr 7:117,675,720...117,680,004
JBrowse link
G Slc41a2 solute carrier family 41 member 2 decreases expression EXP Oxycodone results in decreased expression of SLC41A2 mRNA CTD PMID:23439660 NCBI chr 7:26,522,314...26,607,861
Ensembl chr 7:26,522,314...26,607,861
JBrowse link
G Slc49a4 solute carrier family 49 member 4 increases expression EXP Oxycodone results in increased expression of SLC49A4 mRNA CTD PMID:23439660 NCBI chr11:68,198,709...68,272,766
Ensembl chr11:68,198,709...68,272,758
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression EXP Oxycodone results in decreased expression of SLC6A9 mRNA CTD PMID:23439660 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slc7a7 solute carrier family 7 member 7 decreases expression EXP Oxycodone results in decreased expression of SLC7A7 mRNA CTD PMID:23439660 NCBI chr15:33,013,346...33,059,733
Ensembl chr15:33,013,504...33,051,129
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases expression EXP Oxycodone results in increased expression of SLCO1B2 mRNA CTD PMID:23439660 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression EXP Oxycodone results in decreased expression of SLPI mRNA CTD PMID:23439660 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 increases expression EXP Oxycodone results in increased expression of SMARCD2 mRNA CTD PMID:23439660 NCBI chr10:94,451,866...94,460,732
Ensembl chr10:94,451,866...94,460,732
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Oxycodone results in decreased expression of STAC3 mRNA CTD PMID:23439660 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Sulf2 sulfatase 2 increases expression EXP Oxycodone results in increased expression of SULF2 mRNA CTD PMID:23439660 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP Oxycodone results in decreased expression of SULT1A2 mRNA CTD PMID:23439660 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sycp3 synaptonemal complex protein 3 increases expression EXP Oxycodone results in increased expression of SYCP3 mRNA CTD PMID:23439660 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression EXP Oxycodone results in decreased expression of TARS1 mRNA CTD PMID:23439660 NCBI chr 2:61,394,632...61,414,115
Ensembl chr 2:61,394,770...61,414,102
JBrowse link
G Thumpd1 THUMP domain containing 1 decreases expression EXP Oxycodone results in decreased expression of THUMPD1 mRNA CTD PMID:23439660 NCBI chr 1:189,457,582...190,370,515 JBrowse link
G Timm8a1 translocase of inner mitochondrial membrane 8A1 increases expression EXP Oxycodone results in increased expression of TIMM8A mRNA CTD PMID:23439660 NCBI chr  X:105,351,714...105,355,722
Ensembl chr  X:105,352,402...105,355,716
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression EXP Oxycodone results in increased expression of TLE1 mRNA CTD PMID:23439660 NCBI chr 5:88,546,607...88,630,277
Ensembl chr 5:88,546,568...88,629,491
JBrowse link
G Tmem19 transmembrane protein 19 decreases expression EXP Oxycodone results in decreased expression of TMEM19 mRNA CTD PMID:23439660 NCBI chr 7:58,316,583...58,343,761
Ensembl chr 7:58,316,514...58,343,145
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression EXP Oxycodone results in increased expression of TSC22D3 mRNA CTD PMID:23439660 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP Oxycodone results in increased expression of TSKU mRNA CTD PMID:23439660 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Oxycodone results in decreased expression of TUBB5 mRNA CTD PMID:23439660 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Oxycodone results in increased expression of UGT1A1 mRNA CTD PMID:23439660 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Usp12 ubiquitin specific peptidase 12 decreases expression EXP Oxycodone results in decreased expression of USP12 mRNA CTD PMID:23439660 NCBI chr12:10,037,686...10,087,685
Ensembl chr12:10,063,117...10,087,685
JBrowse link
G Ust5r integral membrane transport protein UST5r decreases expression EXP Oxycodone results in decreased expression of UST5R mRNA CTD PMID:23439660 NCBI chr 1:224,457,895...224,533,994
Ensembl chr 1:224,457,900...224,533,219
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression EXP Oxycodone results in decreased expression of VASP mRNA CTD PMID:23439660 NCBI chr 1:80,170,608...80,185,882
Ensembl chr 1:80,170,619...80,185,882
JBrowse link
G Vim vimentin decreases expression EXP Oxycodone results in decreased expression of VIM mRNA CTD PMID:23439660 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Zfp354a zinc finger protein 354A increases expression EXP Oxycodone results in increased expression of ZNF354A mRNA CTD PMID:23439660 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        pharmacological role 18847
          analgesic 13086
            opioid analgesic 631
              oxycodone 164
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            heteroorganic entity 19217
                              organonitrogen compound 18386
                                alkaloid 5364
                                  isoquinoline alkaloid 1130
                                    morphinane alkaloid 658
                                      morphinan 637
                                        oxycodone 164
paths to the root