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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organic trisulfide
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Accession:CHEBI:78493 term browser browse the term
Definition:An organosulfur compound with structure Compounds of structure R(1)SSSR(2) in which R(1) and R(2) are organic groups.
Synonyms:related_synonym: Formula=S3R2;   SMILES=[*]SSS[*];   organic trisulfides


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diallyl trisulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression
ISO diallyl trisulfide results in increased expression of ABCB1 mRNA
diallyl trisulfide results in decreased expression of ABCB1 protein
CTD PMID:22397993 PMID:24788927 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO diallyl trisulfide results in increased expression of ABCC1 mRNA CTD PMID:22397993 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO diallyl trisulfide results in decreased expression of ABCC3 mRNA CTD PMID:22397993 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
decreases expression
ISO diallyl trisulfide results in increased expression of ABCC4 mRNA
diallyl trisulfide results in decreased expression of ABCC4 mRNA
CTD PMID:22397993 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO diallyl trisulfide results in increased expression of ABCC6 mRNA CTD PMID:22397993 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of ACTA2 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of ACTA2 protein] CTD PMID:28157488 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actg1 actin, gamma 1 decreases expression ISO diallyl trisulfide results in decreased expression of ACTG1 protein CTD PMID:19550292 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Ak2 adenylate kinase 2 increases expression ISO diallyl trisulfide results in increased expression of AK2 protein CTD PMID:16344271 NCBI chr 5:147,185,474...147,204,050
Ensembl chr 5:147,185,474...147,204,050
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression
EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]
diallyl trisulfide results in decreased phosphorylation of AKT1 protein
diallyl trisulfide results in increased phosphorylation of AKT1 protein
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; pyrazolanthrone inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]
diallyl trisulfide results in decreased expression of AKT1 mRNA; diallyl trisulfide results in decreased expression of AKT1 protein
CTD PMID:19823037 PMID:22020565 PMID:23453443 PMID:23663050 PMID:23754639 PMID:24415872 PMID:24489685 PMID:27566995 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases activity
decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased activity of ALDH1 protein
diallyl trisulfide results in decreased expression of ALDH1A1 protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased activity of ALDH1 protein]
CTD PMID:27129776 PMID:29626521 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO diallyl trisulfide results in increased expression of ALPL protein CTD PMID:19550292 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] CTD PMID:28574600 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Anxa1 annexin A1 increases expression ISO diallyl trisulfide results in increased expression of ANXA1 mRNA; diallyl trisulfide results in increased expression of ANXA1 protein CTD PMID:16344271 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Ar androgen receptor decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of AR mRNA; diallyl trisulfide results in decreased expression of AR protein
diallyl trisulfide inhibits the reaction [Metribolone affects the localization of AR protein]
CTD PMID:19622577 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression
increases expression
ISO diallyl trisulfide results in decreased expression of ATP5PD protein
diallyl trisulfide results in increased expression of ATP5PD protein
CTD PMID:16344271 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation ISO diallyl trisulfide results in decreased phosphorylation of BAD protein CTD PMID:27566995 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
multiple interactions
increases activity
ISO diallyl trisulfide results in increased expression of BAK1 protein
SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]
CTD PMID:17513609 PMID:23412769 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
increases activity
ISO
EXP
diallyl trisulfide results in increased expression of BAX mRNA; diallyl trisulfide results in increased expression of BAX protein
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of BAX protein]
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of BAX protein]
diallyl trisulfide results in increased activity of BAX protein
CTD PMID:19823037 PMID:23412769 PMID:23754639 PMID:24415872 PMID:24460275 PMID:29087013 PMID:31115753 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO diallyl trisulfide results in increased expression of BBC3 mRNA; diallyl trisulfide results in increased expression of BBC3 protein CTD PMID:24460275 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
diallyl trisulfide results in decreased expression of BCL2; diallyl trisulfide results in decreased expression of BCL2 mRNA; diallyl trisulfide results in decreased expression of BCL2 protein
diallyl trisulfide inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]
Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]
CTD PMID:17513609 PMID:19823037 PMID:20055834 PMID:22578287 PMID:22595511 PMID:23754639 PMID:24415872 PMID:24460275 PMID:25205294 PMID:29087013 PMID:31115753 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO diallyl trisulfide results in decreased expression of BCL2L1 protein CTD PMID:17513609 PMID:20055834 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO diallyl trisulfide results in decreased expression of BID protein CTD PMID:22578287 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression
decreases expression
ISO diallyl trisulfide results in increased expression of BIRC2 protein
diallyl trisulfide results in decreased expression of BIRC2 protein
CTD PMID:21411500 PMID:22578287 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
decreases expression
ISO diallyl trisulfide results in increased expression of BIRC5 protein
diallyl trisulfide results in decreased expression of BIRC5 protein
diallyl trisulfide results in increased expression of BIRC5 mRNA; diallyl trisulfide results in increased expression of BIRC5 protein
CTD PMID:21411500 PMID:23754639 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger affects expression ISO diallyl trisulfide affects the expression of BMI1 protein CTD PMID:27129776 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Btf3 basic transcription factor 3 increases expression ISO diallyl trisulfide results in increased expression of BTF3 protein CTD PMID:16344271 NCBI chr 2:28,417,316...28,424,436
Ensembl chr 2:28,417,579...28,423,762
JBrowse link
G Calr calreticulin increases expression ISO diallyl trisulfide results in increased expression of CALR protein CTD PMID:19550292 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression ISO diallyl trisulfide results in decreased expression of CAPZA1 protein CTD PMID:16344271 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
diallyl trisulfide results in increased activity of CASP3 protein
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]
diallyl trisulfide results in increased expression of CASP3 mRNA
CTD PMID:20055834 PMID:21574149 PMID:22578287 PMID:22595511 PMID:23453443 PMID:23754639 PMID:24295472 PMID:25205294 PMID:25896937 PMID:27566995 PMID:28571773 PMID:29087013 PMID:31115753 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
increases cleavage
ISO diallyl trisulfide results in increased activity of CASP8 protein
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein]
CTD PMID:22578287 PMID:22595511 PMID:28571773 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
ISO [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein]
diallyl trisulfide results in increased activity of CASP9 protein
CTD PMID:20055834 PMID:22578287 PMID:22595511 PMID:28571773 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of CAT protein] CTD PMID:24295472 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein] CTD PMID:20229525 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccnb1 cyclin B1 increases expression
affects localization
multiple interactions
ISO diallyl trisulfide results in increased expression of CCNB1 protein
diallyl trisulfide affects the localization of CCNB1 protein
diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]
CTD PMID:19823037 PMID:20143254 PMID:24415872 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
ISO diallyl trisulfide results in decreased expression of CCND1 mRNA; diallyl trisulfide results in decreased expression of CCND1 protein
diallyl trisulfide results in increased expression of CCND1 mRNA; diallyl trisulfide results in increased expression of CCND1 protein
CTD PMID:14693049 PMID:19823037 PMID:23430952 PMID:24415872 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
decreases expression
ISO diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDC25C protein; diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein; EUK-134 inhibits the reaction [diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein]
diallyl trisulfide results in decreased expression of CDC25C protein
CTD PMID:16707465 PMID:20143254 PMID:23754639 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein] CTD PMID:23412769 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
affects localization
ISO diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDK1 protein
diallyl trisulfide affects the localization of CDK1 protein
CTD PMID:20143254 PMID:23754639 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO diallyl trisulfide results in increased expression of CDKN1A mRNA; diallyl trisulfide results in increased expression of CDKN1A protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]
CTD PMID:16222732 PMID:17937621 PMID:23754639 PMID:24415872 PMID:29626521 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO diallyl trisulfide results in increased expression of CDKN1B protein CTD PMID:14693049 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of CEBPA mRNA; diallyl trisulfide results in decreased expression of CEBPA protein
[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]
CTD PMID:22137902 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression
ISO [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]
diallyl trisulfide results in decreased expression of CEBPB mRNA; diallyl trisulfide results in decreased expression of CEBPB protein
CTD PMID:22137902 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cfl1 cofilin 1 decreases expression ISO diallyl trisulfide results in decreased expression of CFL1 protein CTD PMID:16344271 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO diallyl trisulfide results in decreased expression of CFLAR protein CTD PMID:25205294 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cldn1 claudin 1 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN1 mRNA; diallyl trisulfide results in decreased expression of CLDN1 protein CTD PMID:24084732 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn2 claudin 2 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN2 mRNA; diallyl trisulfide results in decreased expression of CLDN2 protein CTD PMID:24084732 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cldn3 claudin 3 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN3 mRNA; diallyl trisulfide results in decreased expression of CLDN3 protein CTD PMID:24084732 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn4 claudin 4 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN4 mRNA; diallyl trisulfide results in decreased expression of CLDN4 protein CTD PMID:24084732 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn5 claudin 5 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN5 mRNA; diallyl trisulfide results in decreased expression of CLDN5 protein CTD PMID:24084732 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Cstb cystatin B decreases expression ISO diallyl trisulfide results in decreased expression of CSTB protein CTD PMID:16344271 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctnnb1 catenin beta 1 increases cleavage
decreases expression
multiple interactions
decreases phosphorylation
ISO diallyl trisulfide results in increased cleavage of CTNNB1 protein
diallyl trisulfide results in decreased expression of CTNNB1 protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein]
diallyl trisulfide results in decreased phosphorylation of CTNNB1 protein
CTD PMID:22578287 PMID:23663050 PMID:29626521 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cul3 cullin 3 decreases expression EXP diallyl trisulfide results in decreased expression of CUL3 protein CTD PMID:23453443 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBA protein] CTD PMID:29087013 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBB protein] CTD PMID:29087013 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein] CTD PMID:31115753 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein] CTD PMID:28115069 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein] CTD PMID:28115069 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP diallyl trisulfide inhibits the reaction [n-hexane results in increased activity of CYP2B1 protein] CTD PMID:28115069 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
EXP diallyl trisulfide results in decreased expression of CYP2E1 protein
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]
CTD PMID:28115069 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO diallyl trisulfide results in decreased expression of CYP7A1 mRNA CTD PMID:16382202 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dach1 dachshund family transcription factor 1 increases expression
multiple interactions
ISO diallyl trisulfide results in increased expression of DACH1 mRNA
FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA]
CTD PMID:27129776 NCBI chr15:82,095,003...82,482,272
Ensembl chr15:82,099,159...82,482,009
JBrowse link
G Ddt D-dopachrome tautomerase decreases expression ISO diallyl trisulfide results in decreased expression of DDT protein CTD PMID:16344271 NCBI chr20:13,827,153...13,829,624
Ensembl chr20:13,827,132...13,831,588
JBrowse link
G Des desmin multiple interactions ISO diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of DES protein] CTD PMID:28157488 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases degradation ISO diallyl trisulfide results in increased degradation of DFFA protein CTD PMID:23754639 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 decreases expression ISO diallyl trisulfide results in decreased expression of DNAJC27 protein CTD PMID:19550292 NCBI chr 6:28,515,054...28,544,756
Ensembl chr 6:28,515,025...28,544,790
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO diallyl trisulfide inhibits the reaction [Glucose results in increased expression of DNM1L protein] CTD PMID:31115753 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dynlrb1 dynein light chain roadblock-type 1 decreases expression ISO diallyl trisulfide results in decreased expression of DYNLRB1 protein CTD PMID:19550292 NCBI chr 3:150,761,329...150,782,493
Ensembl chr 3:150,761,329...150,782,493
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO diallyl trisulfide results in decreased expression of EGFR protein CTD PMID:23754639 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H decreases expression ISO diallyl trisulfide results in decreased expression of EIF4H protein CTD PMID:16344271 NCBI chr12:25,093,119...25,109,805
Ensembl chr12:25,093,149...25,109,799
JBrowse link
G Eno1 enolase 1 increases expression ISO diallyl trisulfide results in increased expression of ENO1 protein CTD PMID:16344271 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP diallyl trisulfide results in increased expression of EPHX1 mRNA CTD PMID:20650352 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO diallyl trisulfide results in increased expression of FAS mRNA; diallyl trisulfide results in increased expression of FAS protein CTD PMID:19823037 PMID:24415872 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN CTD PMID:22137902 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Folr1 folate receptor alpha increases expression ISO diallyl trisulfide results in increased expression of FOLR1 mRNA CTD PMID:11925593 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects localization ISO diallyl trisulfide affects the localization of FOS protein CTD PMID:25927362 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO diallyl trisulfide results in decreased expression of FOXP3 mRNA CTD PMID:20979868 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Foxq1 forkhead box Q1 multiple interactions
decreases expression
ISO diallyl trisulfide results in decreased expression of and affects the localization of FOXQ1 protein; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased activity of ALDH1 protein]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA]
diallyl trisulfide results in decreased expression of FOXQ1 mRNA
CTD PMID:27129776 NCBI chr17:34,224,308...34,226,941
Ensembl chr17:34,224,818...34,226,453
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein CTD PMID:16707465 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] CTD PMID:16707465 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions
decreases expression
ISO [diallyl trisulfide results in decreased expression of FTMT protein] which results in increased abundance of Iron; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein] CTD PMID:21616139 NCBI chr18:47,294,292...47,295,541
Ensembl chr18:47,294,292...47,295,541
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO diallyl trisulfide results in increased expression of FUBP1 protein CTD PMID:16344271 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO diallyl trisulfide results in increased expression of GADD45A mRNA CTD PMID:17937621 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO diallyl trisulfide results in decreased expression of GAPDH protein CTD PMID:16344271 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
increases phosphorylation
EXP
ISO
diallyl trisulfide results in decreased expression of GSK3B protein
diallyl trisulfide results in decreased expression of GSK3B protein modified form
diallyl trisulfide results in increased phosphorylation of GSK3B protein
CTD PMID:23453443 PMID:23663050 PMID:29626521 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP diallyl trisulfide results in increased expression of GSTA5 mRNA CTD PMID:20650352 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
increases expression
multiple interactions
ISO
EXP
diallyl trisulfide results in decreased expression of GSTP1 mRNA; diallyl trisulfide results in decreased expression of GSTP1 protein
diallyl trisulfide results in increased expression of GSTP1 mRNA
[diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; [diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and results in increased activity of GSTP1 protein
CTD PMID:16344271 PMID:20237067 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO diallyl trisulfide results in decreased expression of HES1 mRNA CTD PMID:23430952 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 decreases expression ISO diallyl trisulfide results in decreased expression of HEY1 mRNA CTD PMID:23430952 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 decreases expression ISO diallyl trisulfide results in decreased expression of HEY2 mRNA CTD PMID:23430952 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
diallyl trisulfide results in decreased expression of HIF1A protein
CTD PMID:28574600 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein]; [diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
diallyl trisulfide results in increased expression of HMOX1 mRNA; diallyl trisulfide results in increased expression of HMOX1 protein
CTD PMID:23412769 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO diallyl trisulfide results in increased expression of HNF4A mRNA CTD PMID:16382202 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO diallyl trisulfide results in decreased expression of HNRNPA2B1 protein CTD PMID:16344271 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like increases expression ISO diallyl trisulfide results in increased expression of HNRNPDL protein CTD PMID:16344271 NCBI chr14:11,199,114...11,204,670
Ensembl chr14:11,198,896...11,202,669
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 increases expression ISO diallyl trisulfide results in increased expression of HNRNPH1 protein CTD PMID:16344271 NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO diallyl trisulfide results in decreased expression of HSPA5 protein CTD PMID:19550292 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO diallyl trisulfide results in decreased expression of HSPA8 protein CTD PMID:19550292 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO diallyl trisulfide results in decreased expression of HSPA9 protein CTD PMID:19550292 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO diallyl trisulfide results in decreased expression of HSPD1 protein CTD PMID:19550292 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO diallyl trisulfide results in decreased expression of HYOU1 protein CTD PMID:19550292 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Il10 interleukin 10 multiple interactions ISO diallyl trisulfide results in decreased expression of and results in decreased secretion of IL10 protein CTD PMID:20979868 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]] CTD PMID:25500681 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression ISO diallyl trisulfide results in increased expression of INA protein CTD PMID:19550292 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Itga4 integrin subunit alpha 4 decreases expression ISO diallyl trisulfide results in decreased expression of ITGA4 protein CTD PMID:28741790 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO diallyl trisulfide results in decreased expression of ITGA5 protein CTD PMID:28741790 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO diallyl trisulfide results in decreased expression of ITGAV protein CTD PMID:28741790 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO diallyl trisulfide results in decreased expression of ITGB1 protein CTD PMID:28741790 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression ISO diallyl trisulfide results in decreased expression of ITGB3 protein CTD PMID:28741790 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO diallyl trisulfide results in decreased expression of ITGB4 protein CTD PMID:28741790 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation
affects localization
increases activity
increases expression
multiple interactions
ISO
EXP
diallyl trisulfide results in increased phosphorylation of JUN protein
diallyl trisulfide affects the localization of JUN protein
diallyl trisulfide results in increased activity of JUN protein
diallyl trisulfide results in increased expression of JUN protein
[diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]
MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein]
CTD PMID:16707465 PMID:20237067 PMID:25927362 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases activity ISO diallyl trisulfide results in decreased activity of KCNA5 protein CTD PMID:23272117 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 multiple interactions ISO diallyl trisulfide binds to and results in decreased activity of KCND3 protein CTD PMID:23272117 NCBI chr 2:207,923,775...208,140,727
Ensembl chr 2:207,923,775...208,140,727
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO diallyl trisulfide results in decreased expression of and results in decreased activity of KCNH2 protein
diallyl trisulfide results in decreased activity of KCNH2 protein
CTD PMID:23272117 PMID:24504171 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
affects binding
multiple interactions
EXP
ISO
diallyl trisulfide results in decreased expression of KEAP1 protein
diallyl trisulfide binds to KEAP1 protein
diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein]
CTD PMID:23453443 PMID:24489685 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO diallyl trisulfide results in increased expression of KIT protein CTD PMID:23663050 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Krt10 keratin 10 increases expression ISO diallyl trisulfide results in increased expression of KRT10 protein CTD PMID:19550292 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krt8 keratin 8 decreases expression ISO diallyl trisulfide results in decreased expression of KRT8 protein CTD PMID:16344271 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G L1cam L1 cell adhesion molecule multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM mRNA]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM protein] CTD PMID:28574600 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 increases expression ISO diallyl trisulfide results in increased expression of LAMTOR5 mRNA CTD PMID:11925594 NCBI chr 2:210,034,095...210,039,451
Ensembl chr 2:210,034,095...210,039,451
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
decreases response to substance
decreases expression
ISO LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]
LDHA protein results in decreased susceptibility to diallyl trisulfide
diallyl trisulfide results in decreased expression of LDHA protein
CTD PMID:27566995 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lox lysyl oxidase multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:28574600 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Loxl4 lysyl oxidase-like 4 multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOXL4 mRNA] CTD PMID:28574600 NCBI chr 1:261,833,365...261,853,599
Ensembl chr 1:261,835,992...261,853,495
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO MAP2K4 protein affects the reaction [diallyl trisulfide results in increased abundance of Reactive Oxygen Species]; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] CTD PMID:16707465 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 affects expression
multiple interactions
ISO diallyl trisulfide affects the expression of MAP2K7 protein
MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein]
CTD PMID:16707465 PMID:21695758 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 affects expression ISO diallyl trisulfide affects the expression of MAP3K3 protein CTD PMID:21695758 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein]
diallyl trisulfide results in decreased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]
diallyl trisulfide results in decreased expression of MAPK1 protein
CTD PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 PMID:29087013 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
decreases phosphorylation
increases phosphorylation
multiple interactions
ISO
EXP
diallyl trisulfide results in decreased expression of MAPK3 protein
diallyl trisulfide results in decreased phosphorylation of MAPK3 protein
diallyl trisulfide results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]
CTD PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 PMID:29087013 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO diallyl trisulfide results in decreased expression of MCL1 protein CTD PMID:28571773 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression
increases degradation
ISO diallyl trisulfide results in decreased expression of MDM2 protein
diallyl trisulfide results in increased degradation of MDM2 protein
CTD PMID:23754639 PMID:24415872 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mir143 microRNA 143 increases expression ISO diallyl trisulfide results in increased expression of MIR143 mRNA CTD PMID:23430952 NCBI chr18:56,971,273...56,971,377
Ensembl chr18:56,971,273...56,971,377
JBrowse link
G Mir145 microRNA 145 increases expression ISO diallyl trisulfide results in increased expression of MIR145 mRNA CTD PMID:23430952 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir200b microRNA 200b increases expression ISO diallyl trisulfide results in increased expression of MIR200B mRNA CTD PMID:23430952 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir200c microRNA 200c increases expression ISO diallyl trisulfide results in increased expression of MIR200C mRNA CTD PMID:23430952 NCBI chr 4:157,236,786...157,236,854 JBrowse link
G Mir21 microRNA 21 decreases expression ISO diallyl trisulfide results in decreased expression of MIR21 mRNA CTD PMID:23430952 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir221 microRNA 221 decreases expression ISO diallyl trisulfide results in decreased expression of MIR221 mRNA CTD PMID:23663050 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
decreases activity
ISO diallyl trisulfide results in decreased expression of and results in decreased activity of MMP2 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]
diallyl trisulfide results in decreased expression of MMP2 mRNA; diallyl trisulfide results in decreased expression of MMP2 protein
CTD PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 PMID:28574600 PMID:28741790 PMID:30396169 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO diallyl trisulfide results in decreased expression of MMP7 protein CTD PMID:21695758 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
decreases activity
affects expression
ISO diallyl trisulfide results in decreased expression of and results in decreased activity of MMP9 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]
diallyl trisulfide results in decreased expression of MMP9 mRNA; diallyl trisulfide results in decreased expression of MMP9 protein
diallyl trisulfide affects the expression of MMP9 protein
CTD PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 PMID:28741790 PMID:30396169 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO diallyl trisulfide results in decreased expression of MTOR protein CTD PMID:23754639 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of MYC mRNA; diallyl trisulfide results in decreased expression of MYC protein
FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]
CTD PMID:23754639 PMID:27129776 PMID:29626521 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] CTD PMID:25500681 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nanog Nanog homeobox decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of NANOG protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein]
CTD PMID:29626521 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 decreases expression EXP diallyl trisulfide results in decreased expression of NCF1 protein CTD PMID:29087013 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO diallyl trisulfide results in increased expression of NDRG1 mRNA CTD PMID:17937621 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases localization
increases activity
increases expression
EXP
ISO
[diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; diallyl trisulfide promotes the reaction [Glucose results in increased expression of and affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein]
diallyl trisulfide results in increased localization of NFE2L2 protein
diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
Acetylcysteine inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; Dithiothreitol inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]
diallyl trisulfide results in increased activity of NFE2L2 protein
diallyl trisulfide results in increased expression of NFE2L2 mRNA; diallyl trisulfide results in increased expression of NFE2L2 protein
CTD PMID:18768114 PMID:20237067 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases phosphorylation
increases expression
increases phosphorylation
decreases degradation
ISO diallyl trisulfide results in decreased phosphorylation of NFKBIA protein
diallyl trisulfide results in increased expression of NFKBIA mRNA; diallyl trisulfide results in increased expression of NFKBIA protein
diallyl trisulfide results in increased phosphorylation of NFKBIA protein
diallyl trisulfide results in decreased degradation of NFKBIA protein
CTD PMID:23663050 PMID:24788927 PMID:25205294 PMID:25927362 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 affects expression
multiple interactions
ISO diallyl trisulfide affects the expression of NOS2 protein
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
CTD PMID:21695758 PMID:25500681 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
increases phosphorylation
decreases degradation
ISO diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein]; wortmannin inhibits the reaction [diallyl trisulfide results in increased phosphorylation of NOS3 protein]
diallyl trisulfide results in increased expression of NOS3 protein
diallyl trisulfide results in decreased degradation of NOS3 protein
CTD PMID:20229525 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of NOTCH1 mRNA; diallyl trisulfide results in decreased expression of NOTCH1 protein
NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein]
CTD PMID:23430952 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
EXP
ISO
diallyl trisulfide results in increased expression of NQO1 mRNA
diallyl trisulfide results in increased expression of NQO1 protein
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]
diallyl trisulfide results in increased expression of NQO1 mRNA; diallyl trisulfide results in increased expression of NQO1 protein
CTD PMID:20650352 PMID:24489685 PMID:30317421 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nucb1 nucleobindin 1 decreases expression ISO diallyl trisulfide results in decreased expression of NUCB1 protein CTD PMID:19550292 NCBI chr 1:101,480,160...101,511,029
Ensembl chr 1:101,480,145...101,500,850
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of OGDH protein] CTD PMID:24295472 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO diallyl trisulfide results in increased cleavage of PARP1 protein
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]
CTD PMID:20055834 PMID:22578287 PMID:25205294 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of PCNA protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]
CTD PMID:29626521 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression ISO diallyl trisulfide results in increased expression of PGK1 protein CTD PMID:16344271 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein] CTD PMID:25896937 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression ISO diallyl trisulfide affects the expression of PLAUR protein CTD PMID:27129776 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Plin3 perilipin 3 increases expression ISO diallyl trisulfide results in increased expression of PLIN3 protein CTD PMID:16344271 NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO diallyl trisulfide results in increased expression of PPARA mRNA CTD PMID:16382202 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity
decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased activity of PPARG protein
diallyl trisulfide results in decreased expression of PPARG mRNA; diallyl trisulfide results in decreased expression of PPARG protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in decreased expression of and results in decreased activity of PPARG protein]; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]
CTD PMID:22137902 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prom1 prominin 1 decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of PROM1 protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein]
CTD PMID:29626521 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO diallyl trisulfide results in decreased expression of PSMA1 protein CTD PMID:19550292 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions
decreases expression
ISO diallyl trisulfide affects the expression of PTGS2 protein
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]
diallyl trisulfide results in decreased expression of PTGS2 mRNA
CTD PMID:15523159 PMID:21695758 PMID:25500681 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO diallyl trisulfide results in decreased expression of PTK2 protein; diallyl trisulfide results in decreased expression of PTK2 protein modified form CTD PMID:28741790 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rbp1 retinol binding protein 1 multiple interactions ISO diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of RBP1 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in increased expression of RBP1 protein] CTD PMID:28157488 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
ISO
EXP
diallyl trisulfide results in decreased phosphorylation of and affects the localization of RELA protein
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of RELA protein]
diallyl trisulfide results in decreased expression of RELA mRNA; diallyl trisulfide results in decreased expression of RELA protein
CTD PMID:24788927 PMID:25927362 PMID:29087013 PMID:30396169 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO diallyl trisulfide results in increased expression of S100A11 protein CTD PMID:16344271 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO diallyl trisulfide results in increased expression of S100A6 mRNA CTD PMID:11925593 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO diallyl trisulfide results in increased expression of SERPINE2 mRNA CTD PMID:11925594 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Shc1 SHC adaptor protein 1 increases phosphorylation
affects response to substance
decreases response to substance
multiple interactions
ISO diallyl trisulfide results in increased phosphorylation of SHC1 protein
SHC1 protein affects the susceptibility to diallyl trisulfide
SHC1 protein modified form results in decreased susceptibility to diallyl trisulfide
pyrazolanthrone inhibits the reaction [diallyl trisulfide results in increased phosphorylation of SHC1 protein]; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]
CTD PMID:21616139 PMID:22020565 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
decreases expression
ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein] CTD PMID:27566995 PMID:28574600 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI2 protein] CTD PMID:28574600 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP diallyl trisulfide results in increased expression of SOD1 protein CTD PMID:23453443 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
EXP
ISO
diallyl trisulfide results in increased expression of SOD2 protein
SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
CTD PMID:23412769 PMID:23453443 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 increases expression ISO diallyl trisulfide results in increased expression of SRSF1 protein CTD PMID:16344271 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197
JBrowse link
G Tagln2 transgelin 2 increases expression ISO diallyl trisulfide results in increased expression of TAGLN2 protein CTD PMID:16344271 NCBI chr13:90,807,196...90,814,119
Ensembl chr13:90,807,199...90,814,119
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO diallyl trisulfide results in decreased expression of TARDBP protein CTD PMID:30317421 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO diallyl trisulfide results in decreased expression of and results in decreased secretion of TGFB1 protein CTD PMID:20979868 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO diallyl trisulfide results in increased expression of TIMP1 mRNA; diallyl trisulfide results in increased expression of TIMP1 protein CTD PMID:24084732 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO diallyl trisulfide results in increased expression of TIMP2 mRNA; diallyl trisulfide results in increased expression of TIMP2 protein CTD PMID:24084732 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:25500681 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor decreases secretion
multiple interactions
decreases expression
ISO diallyl trisulfide results in decreased secretion of TNF protein
[ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]
diallyl trisulfide results in decreased expression of TNF mRNA
CTD PMID:16110831 PMID:17448272 PMID:25500681 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance
multiple interactions
ISO diallyl trisulfide results in increased susceptibility to TNFSF10 protein
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein
CTD PMID:28571773 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 affects localization
multiple interactions
increases expression
ISO diallyl trisulfide affects the localization of TP53 protein
diallyl trisulfide results in increased expression of and affects the localization of TP53 protein
diallyl trisulfide results in increased expression of TP53 mRNA; diallyl trisulfide results in increased expression of TP53 protein
CTD PMID:19823037 PMID:23754639 PMID:24415872 PMID:28571773 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO diallyl trisulfide results in decreased expression of TPT1 protein CTD PMID:16344271 NCBI chr15:57,891,680...57,894,504
Ensembl chr15:57,891,680...57,894,504
JBrowse link
G Twist1 twist family bHLH transcription factor 1 decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of TWIST1 protein
LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]
CTD PMID:27566995 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Txn1 thioredoxin 1 decreases expression
decreases reduction
multiple interactions
ISO diallyl trisulfide results in decreased expression of TXN protein
diallyl trisulfide results in decreased reduction of TXN protein
TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein]
CTD PMID:28574600 PMID:30396169 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions
ISO diallyl trisulfide results in increased expression of TXNIP protein
TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein]
CTD PMID:30396169 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 decreases expression ISO diallyl trisulfide results in decreased expression of UCHL1 protein CTD PMID:19550292 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP diallyl trisulfide results in increased expression of UGT1A1 mRNA CTD PMID:20650352 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression ISO diallyl trisulfide results in decreased expression of VDAC1 protein CTD PMID:16344271 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdac2 voltage-dependent anion channel 2 decreases expression ISO diallyl trisulfide results in decreased expression of VDAC2 protein CTD PMID:16344271 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of VEGFA mRNA; diallyl trisulfide results in decreased expression of VEGFA protein
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; diallyl trisulfide results in decreased expression of and results in decreased secretion of VEGFA protein; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein]
CTD PMID:23430952 PMID:23754639 PMID:28574600 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin decreases expression
multiple interactions
ISO diallyl trisulfide results in decreased expression of VIM protein
SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]
CTD PMID:19550292 PMID:23412769 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases degradation
decreases expression
decreases response to substance
multiple interactions
ISO diallyl trisulfide results in increased degradation of XIAP protein
diallyl trisulfide results in decreased expression of XIAP protein
XIAP protein results in decreased susceptibility to diallyl trisulfide
Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]
CTD PMID:21411500 PMID:22578287 PMID:25205294 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19775
    chemical entity 19775
      atom 19774
        nonmetal atom 19655
          sulfur atom 16388
            sulfur molecular entity 16388
              organosulfur compound 15271
                organic trisulfide 195
                  1,2,3,5,6,8-Hexathionane 0
                  4,7-Dihydro-5-(4-methyl-3-pentenyl)-1,2,3-trithiepin 0
                  Diethyl trisulfide 0
                  Dimethyl trisulfide 0
                  Dipropyl trisulfide 0
                  Ethyl methyl trisulfide 0
                  Methyl propyl trisulfide 0
                  diallyl trisulfide 195
                  trisulfanediyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19775
    subatomic particle 19774
      composite particle 19774
        hadron 19774
          baryon 19774
            nucleon 19774
              atomic nucleus 19774
                atom 19774
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19584
                        carbon atom 19574
                          organic molecular entity 19574
                            heteroorganic entity 19215
                              organochalcogen compound 18973
                                organosulfur compound 15271
                                  organic trisulfide 195
                                    1,2,3,5,6,8-Hexathionane 0
                                    4,7-Dihydro-5-(4-methyl-3-pentenyl)-1,2,3-trithiepin 0
                                    Diethyl trisulfide 0
                                    Dimethyl trisulfide 0
                                    Dipropyl trisulfide 0
                                    Ethyl methyl trisulfide 0
                                    Methyl propyl trisulfide 0
                                    diallyl trisulfide 195
                                    trisulfanediyl group 0
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