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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases expression decreases expression |
ISO |
diallyl trisulfide results in increased expression of ABCB1 mRNA diallyl trisulfide results in decreased expression of ABCB1 protein |
CTD |
PMID:22397993 PMID:24788927 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of ABCC1 mRNA |
CTD |
PMID:22397993 |
|
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ABCC3 mRNA |
CTD |
PMID:22397993 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases expression decreases expression |
ISO |
diallyl trisulfide results in increased expression of ABCC4 mRNA diallyl trisulfide results in decreased expression of ABCC4 mRNA |
CTD |
PMID:22397993 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of ABCC6 mRNA |
CTD |
PMID:22397993 |
|
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of ACTA2 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of ACTA2 protein] |
CTD |
PMID:28157488 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actg1 |
actin, gamma 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ACTG1 protein |
CTD |
PMID:19550292 |
|
NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
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G |
Ak2 |
adenylate kinase 2 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of AK2 protein |
CTD |
PMID:16344271 |
|
NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases expression increases phosphorylation decreases phosphorylation |
EXP ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] diallyl trisulfide results in decreased expression of AKT1 mRNA; diallyl trisulfide results in decreased expression of AKT1 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; pyrazolanthrone inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:19823037 PMID:22020565 PMID:23453443 PMID:23663050 PMID:23754639 PMID:24415872 PMID:24489685 PMID:27566995 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions decreases expression |
ISO |
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein] diallyl trisulfide results in decreased expression of ALDH1A1 protein |
CTD |
PMID:29626521 |
|
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases expression |
ISO |
diallyl trisulfide results in increased expression of ALPL protein |
CTD |
PMID:19550292 |
|
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] |
CTD |
PMID:28574600 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of ANXA1 mRNA; diallyl trisulfide results in increased expression of ANXA1 protein |
CTD |
PMID:16344271 |
|
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Ar |
androgen receptor |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of AR mRNA; diallyl trisulfide results in decreased expression of AR protein diallyl trisulfide inhibits the reaction [Metribolone affects the localization of AR protein] |
CTD |
PMID:19622577 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
decreases expression increases expression |
ISO |
diallyl trisulfide results in decreased expression of ATP5PD protein diallyl trisulfide results in increased expression of ATP5PD protein |
CTD |
PMID:16344271 |
|
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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G |
Bad |
BCL2-associated agonist of cell death |
decreases phosphorylation |
ISO |
diallyl trisulfide results in decreased phosphorylation of BAD protein |
CTD |
PMID:27566995 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression increases activity multiple interactions |
ISO |
diallyl trisulfide results in increased expression of BAK1 protein diallyl trisulfide results in increased activity of BAK1 protein SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein] |
CTD |
PMID:17513609 PMID:23412769 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression increases activity multiple interactions |
ISO EXP |
diallyl trisulfide results in increased expression of BAX mRNA; diallyl trisulfide results in increased expression of BAX protein diallyl trisulfide results in increased activity of BAX protein diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of BAX protein] diallyl trisulfide inhibits the reaction [Glucose results in increased expression of BAX protein] |
CTD |
PMID:19823037 PMID:23412769 PMID:23754639 PMID:24415872 PMID:24460275 PMID:29087013 PMID:31115753 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of BBC3 mRNA; diallyl trisulfide results in increased expression of BBC3 protein |
CTD |
PMID:24460275 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO EXP |
diallyl trisulfide results in decreased expression of BCL2; diallyl trisulfide results in decreased expression of BCL2 mRNA; diallyl trisulfide results in decreased expression of BCL2 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased expression of BCL2 protein] diallyl trisulfide inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein] |
CTD |
PMID:17513609 PMID:19823037 PMID:20055834 PMID:22578287 PMID:22595511 PMID:23754639 PMID:24415872 PMID:24460275 PMID:25205294 PMID:29087013 PMID:31115753 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of BCL2L1 protein |
CTD |
PMID:17513609 PMID:20055834 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bid |
BH3 interacting domain death agonist |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of BID protein |
CTD |
PMID:22578287 |
|
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression decreases expression |
ISO |
diallyl trisulfide results in increased expression of BIRC2 protein diallyl trisulfide results in decreased expression of BIRC2 protein |
CTD |
PMID:21411500 PMID:22578287 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression decreases expression |
ISO |
diallyl trisulfide results in increased expression of BIRC5 protein diallyl trisulfide results in increased expression of BIRC5 mRNA; diallyl trisulfide results in increased expression of BIRC5 protein diallyl trisulfide results in decreased expression of BIRC5 protein |
CTD |
PMID:21411500 PMID:23754639 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
affects expression |
ISO |
diallyl trisulfide affects the expression of BMI1 protein |
CTD |
PMID:27129776 |
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NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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G |
Btf3 |
basic transcription factor 3 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of BTF3 protein |
CTD |
PMID:16344271 |
|
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
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G |
Calr |
calreticulin |
increases expression |
ISO |
diallyl trisulfide results in increased expression of CALR protein |
CTD |
PMID:19550292 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Capza1 |
capping actin protein of muscle Z-line subunit alpha 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CAPZA1 protein |
CTD |
PMID:16344271 |
|
NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480
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G |
Casp3 |
caspase 3 |
increases activity increases expression multiple interactions increases cleavage |
ISO EXP |
diallyl trisulfide results in increased activity of CASP3 protein diallyl trisulfide results in increased expression of CASP3 mRNA diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]] diallyl trisulfide results in increased cleavage of CASP3 protein [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein] |
CTD |
PMID:20055834 PMID:21574149 PMID:22578287 PMID:22595511 PMID:23453443 PMID:23754639 PMID:24295472 PMID:25205294 PMID:25896937 PMID:27566995 PMID:28571773 PMID:29087013 PMID:31115753 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
increases activity increases cleavage multiple interactions |
ISO |
diallyl trisulfide results in increased activity of CASP8 protein diallyl trisulfide results in increased cleavage of CASP8 protein [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein] |
CTD |
PMID:22578287 PMID:22595511 PMID:28571773 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases activity increases cleavage |
ISO |
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein] diallyl trisulfide results in increased activity of CASP9 protein |
CTD |
PMID:20055834 PMID:22578287 PMID:22595511 PMID:28571773 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions |
EXP |
diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of CAT protein] |
CTD |
PMID:24295472 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
multiple interactions |
ISO |
diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein] |
CTD |
PMID:20229525 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Ccnb1 |
cyclin B1 |
increases expression multiple interactions affects localization |
ISO |
diallyl trisulfide results in increased expression of CCNB1 protein diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein] diallyl trisulfide affects the localization of CCNB1 protein |
CTD |
PMID:19823037 PMID:20143254 PMID:24415872 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
decreases expression increases expression |
ISO |
diallyl trisulfide results in decreased expression of CCND1 mRNA; diallyl trisulfide results in decreased expression of CCND1 protein diallyl trisulfide results in increased expression of CCND1 mRNA; diallyl trisulfide results in increased expression of CCND1 protein |
CTD |
PMID:14693049 PMID:19823037 PMID:23430952 PMID:24415872 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cdc25c |
cell division cycle 25C |
multiple interactions decreases expression |
ISO |
diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDC25C protein; diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein; EUK-134 inhibits the reaction [diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein] diallyl trisulfide results in decreased expression of CDC25C protein |
CTD |
PMID:16707465 PMID:20143254 PMID:23754639 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdh1 |
cadherin 1 |
multiple interactions increases expression |
ISO |
SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein] |
CTD |
PMID:23412769 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions affects localization |
ISO |
diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDK1 protein diallyl trisulfide affects the localization of CDK1 protein |
CTD |
PMID:20143254 PMID:23754639 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO |
diallyl trisulfide results in increased expression of CDKN1A mRNA; diallyl trisulfide results in increased expression of CDKN1A protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein] |
CTD |
PMID:16222732 PMID:17937621 PMID:23754639 PMID:24415872 PMID:29626521 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression |
ISO |
diallyl trisulfide results in increased expression of CDKN1B protein |
CTD |
PMID:14693049 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of CEBPA mRNA; diallyl trisulfide results in decreased expression of CEBPA protein [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein] |
CTD |
PMID:22137902 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
ISO |
[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein] diallyl trisulfide results in decreased expression of CEBPB mRNA; diallyl trisulfide results in decreased expression of CEBPB protein |
CTD |
PMID:22137902 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cfl1 |
cofilin 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CFL1 protein |
CTD |
PMID:16344271 |
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NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CFLAR protein |
CTD |
PMID:25205294 |
|
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Cldn1 |
claudin 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CLDN1 mRNA; diallyl trisulfide results in decreased expression of CLDN1 protein |
CTD |
PMID:24084732 |
|
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn2 |
claudin 2 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CLDN2 mRNA; diallyl trisulfide results in decreased expression of CLDN2 protein |
CTD |
PMID:24084732 |
|
NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838
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G |
Cldn3 |
claudin 3 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CLDN3 mRNA; diallyl trisulfide results in decreased expression of CLDN3 protein |
CTD |
PMID:24084732 |
|
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
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G |
Cldn4 |
claudin 4 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CLDN4 mRNA; diallyl trisulfide results in decreased expression of CLDN4 protein |
CTD |
PMID:24084732 |
|
NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Cldn5 |
claudin 5 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CLDN5 mRNA; diallyl trisulfide results in decreased expression of CLDN5 protein |
CTD |
PMID:24084732 |
|
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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G |
Cstb |
cystatin B |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CSTB protein |
CTD |
PMID:16344271 |
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NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
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G |
Ctnnb1 |
catenin beta 1 |
increases cleavage decreases phosphorylation multiple interactions decreases expression |
ISO |
diallyl trisulfide results in increased cleavage of CTNNB1 protein diallyl trisulfide results in decreased phosphorylation of CTNNB1 protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein] diallyl trisulfide results in decreased expression of CTNNB1 protein |
CTD |
PMID:22578287 PMID:23663050 PMID:29626521 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cul3 |
cullin 3 |
decreases expression |
EXP |
diallyl trisulfide results in decreased expression of CUL3 protein |
CTD |
PMID:23453443 |
|
NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions |
EXP |
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBA protein] |
CTD |
PMID:29087013 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
EXP |
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBB protein] |
CTD |
PMID:29087013 |
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NCBI chr X:13,360,583...13,392,517
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein] |
CTD |
PMID:31115753 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein] |
CTD |
PMID:28115069 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein] |
CTD |
PMID:28115069 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
diallyl trisulfide inhibits the reaction [n-hexane results in increased activity of CYP2B1 protein] |
CTD |
PMID:28115069 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression multiple interactions |
EXP |
diallyl trisulfide results in decreased expression of CYP2E1 protein diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein] |
CTD |
PMID:28115069 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:16382202 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Dach1 |
dachshund family transcription factor 1 |
increases expression multiple interactions |
ISO |
diallyl trisulfide results in increased expression of DACH1 mRNA FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA] |
CTD |
PMID:27129776 |
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NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
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G |
Ddt |
D-dopachrome tautomerase |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of DDT protein |
CTD |
PMID:16344271 |
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NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
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G |
Des |
desmin |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of DES protein] |
CTD |
PMID:28157488 |
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NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dffa |
DNA fragmentation factor subunit alpha |
increases degradation |
ISO |
diallyl trisulfide results in increased degradation of DFFA protein |
CTD |
PMID:23754639 |
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NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
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G |
Dnajc27 |
DnaJ heat shock protein family (Hsp40) member C27 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of DNAJC27 protein |
CTD |
PMID:19550292 |
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NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of DNM1L protein] |
CTD |
PMID:31115753 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dynlrb1 |
dynein light chain roadblock-type 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of DYNLRB1 protein |
CTD |
PMID:19550292 |
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NCBI chr 3:143,742,427...143,764,227
Ensembl chr 3:143,742,586...143,764,227
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G |
Egfr |
epidermal growth factor receptor |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of EGFR protein |
CTD |
PMID:23754639 |
|
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eif4h |
eukaryotic translation initiation factor 4H |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of EIF4H protein |
CTD |
PMID:16344271 |
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NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
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G |
Eno1 |
enolase 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of ENO1 protein |
CTD |
PMID:16344271 |
|
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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G |
Ephx1 |
epoxide hydrolase 1 |
increases expression |
EXP |
diallyl trisulfide results in increased expression of EPHX1 mRNA |
CTD |
PMID:20650352 |
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NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
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G |
Fas |
Fas cell surface death receptor |
increases expression |
ISO |
diallyl trisulfide results in increased expression of FAS mRNA; diallyl trisulfide results in increased expression of FAS protein |
CTD |
PMID:19823037 PMID:24415872 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN |
CTD |
PMID:22137902 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Folr1 |
folate receptor alpha |
increases expression |
ISO |
diallyl trisulfide results in increased expression of FOLR1 mRNA |
CTD |
PMID:11925593 |
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NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
affects localization |
ISO |
diallyl trisulfide affects the localization of FOS protein |
CTD |
PMID:25927362 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxp3 |
forkhead box P3 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of FOXP3 mRNA |
CTD |
PMID:20979868 |
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NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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G |
Foxq1 |
forkhead box Q1 |
multiple interactions decreases expression |
ISO |
diallyl trisulfide results in decreased expression of and affects the localization of FOXQ1 protein; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA] diallyl trisulfide results in decreased expression of FOXQ1 mRNA |
CTD |
PMID:27129776 |
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NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 Ensembl chr17:32,912,744...32,915,377
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein |
CTD |
PMID:16707465 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Ftl1 |
ferritin light chain 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] |
CTD |
PMID:16707465 |
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NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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G |
Ftmt |
ferritin mitochondrial |
multiple interactions decreases expression |
ISO |
[diallyl trisulfide results in decreased expression of FTMT protein] which results in increased abundance of Iron; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein] |
CTD |
PMID:21616139 |
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NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123
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G |
Fubp1 |
far upstream element binding protein 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of FUBP1 protein |
CTD |
PMID:16344271 |
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NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
diallyl trisulfide results in increased expression of GADD45A mRNA |
CTD |
PMID:17937621 |
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of GAPDH protein |
CTD |
PMID:16344271 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases expression increases phosphorylation |
EXP ISO |
diallyl trisulfide results in decreased expression of GSK3B protein diallyl trisulfide results in increased phosphorylation of GSK3B protein diallyl trisulfide results in decreased expression of GSK3B protein modified form |
CTD |
PMID:23453443 PMID:23663050 PMID:29626521 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
increases expression |
EXP |
diallyl trisulfide results in increased expression of GSTA5 mRNA |
CTD |
PMID:20650352 |
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases expression multiple interactions increases expression |
ISO EXP |
diallyl trisulfide results in decreased expression of GSTP1 mRNA; diallyl trisulfide results in decreased expression of GSTP1 protein [diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; [diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and results in increased activity of GSTP1 protein diallyl trisulfide results in increased expression of GSTP1 mRNA |
CTD |
PMID:16344271 PMID:20237067 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Hes1 |
hes family bHLH transcription factor 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HES1 mRNA |
CTD |
PMID:23430952 |
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NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hey1 |
hes-related family bHLH transcription factor with YRPW motif 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HEY1 mRNA |
CTD |
PMID:23430952 |
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NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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G |
Hey2 |
hes-related family bHLH transcription factor with YRPW motif 2 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HEY2 mRNA |
CTD |
PMID:23430952 |
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NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions decreases expression |
ISO |
diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] diallyl trisulfide results in decreased expression of HIF1A protein |
CTD |
PMID:28574600 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] diallyl trisulfide results in increased expression of HMOX1 mRNA; diallyl trisulfide results in increased expression of HMOX1 protein NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein]; [diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] |
CTD |
PMID:23412769 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
increases expression |
ISO |
diallyl trisulfide results in increased expression of HNF4A mRNA |
CTD |
PMID:16382202 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HNRNPA2B1 protein |
CTD |
PMID:16344271 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpdl |
heterogeneous nuclear ribonucleoprotein D-like |
increases expression |
ISO |
diallyl trisulfide results in increased expression of HNRNPDL protein |
CTD |
PMID:16344271 |
|
NCBI chr14:9,558,079...9,563,654
Ensembl chr14:9,557,425...9,562,506
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of HNRNPH1 protein |
CTD |
PMID:16344271 |
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NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HSPA5 protein |
CTD |
PMID:19550292 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HSPA8 protein |
CTD |
PMID:19550292 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HSPA9 protein |
CTD |
PMID:19550292 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HSPD1 protein |
CTD |
PMID:19550292 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Hyou1 |
hypoxia up-regulated 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of HYOU1 protein |
CTD |
PMID:19550292 |
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NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of and results in decreased secretion of IL10 protein |
CTD |
PMID:20979868 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]] |
CTD |
PMID:25500681 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Ina |
internexin neuronal intermediate filament protein, alpha |
increases expression |
ISO |
diallyl trisulfide results in increased expression of INA protein |
CTD |
PMID:19550292 |
|
NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
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G |
Itga4 |
integrin subunit alpha 4 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ITGA4 protein |
CTD |
PMID:28741790 |
|
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
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G |
Itga5 |
integrin subunit alpha 5 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ITGA5 protein |
CTD |
PMID:28741790 |
|
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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G |
Itgav |
integrin subunit alpha V |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ITGAV protein |
CTD |
PMID:28741790 |
|
NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ITGB1 protein |
CTD |
PMID:28741790 |
|
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb3 |
integrin subunit beta 3 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ITGB3 protein |
CTD |
PMID:28741790 |
|
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Itgb4 |
integrin subunit beta 4 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of ITGB4 protein |
CTD |
PMID:28741790 |
|
NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases phosphorylation multiple interactions increases expression increases activity affects localization |
ISO EXP |
diallyl trisulfide results in increased phosphorylation of JUN protein MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein] [diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer] diallyl trisulfide results in increased expression of JUN protein diallyl trisulfide results in increased activity of JUN protein diallyl trisulfide affects the localization of JUN protein |
CTD |
PMID:16707465 PMID:20237067 PMID:25927362 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcna5 |
potassium voltage-gated channel subfamily A member 5 |
decreases activity |
ISO |
diallyl trisulfide results in decreased activity of KCNA5 protein |
CTD |
PMID:23272117 |
|
NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
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G |
Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
multiple interactions |
ISO |
diallyl trisulfide binds to and results in decreased activity of KCND3 protein |
CTD |
PMID:23272117 |
|
NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions decreases activity |
ISO |
diallyl trisulfide results in decreased expression of and results in decreased activity of KCNH2 protein diallyl trisulfide results in decreased activity of KCNH2 protein |
CTD |
PMID:23272117 PMID:24504171 |
|
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression multiple interactions affects binding |
EXP ISO |
diallyl trisulfide results in decreased expression of KEAP1 protein diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein] diallyl trisulfide binds to KEAP1 protein |
CTD |
PMID:23453443 PMID:24489685 |
|
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
diallyl trisulfide results in increased expression of KIT protein |
CTD |
PMID:23663050 |
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NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Krt10 |
keratin 10 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of KRT10 protein |
CTD |
PMID:19550292 |
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NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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G |
Krt8 |
keratin 8 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of KRT8 protein |
CTD |
PMID:16344271 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
L1cam |
L1 cell adhesion molecule |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM mRNA]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM protein] |
CTD |
PMID:28574600 |
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NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
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G |
Lamtor5 |
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of LAMTOR5 mRNA |
CTD |
PMID:11925594 |
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NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395
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G |
Ldha |
lactate dehydrogenase A |
multiple interactions decreases expression decreases response to substance |
ISO |
LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein] diallyl trisulfide results in decreased expression of LDHA protein LDHA protein results in decreased susceptibility to diallyl trisulfide |
CTD |
PMID:27566995 |
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NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] |
CTD |
PMID:28574600 |
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NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
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G |
Loxl4 |
lysyl oxidase-like 4 |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOXL4 mRNA] |
CTD |
PMID:28574600 |
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NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
multiple interactions |
ISO |
MAP2K4 protein affects the reaction [diallyl trisulfide results in increased abundance of Reactive Oxygen Species]; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] |
CTD |
PMID:16707465 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Map2k7 |
mitogen activated protein kinase kinase 7 |
affects expression multiple interactions |
ISO |
diallyl trisulfide affects the expression of MAP2K7 protein MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein] |
CTD |
PMID:16707465 PMID:21695758 |
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NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
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G |
Map3k3 |
mitogen activated protein kinase kinase kinase 3 |
affects expression |
ISO |
diallyl trisulfide affects the expression of MAP3K3 protein |
CTD |
PMID:21695758 |
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NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases expression increases phosphorylation decreases phosphorylation |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein] diallyl trisulfide results in decreased expression of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein] diallyl trisulfide results in decreased phosphorylation of MAPK1 protein |
CTD |
PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 PMID:29087013 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases expression multiple interactions increases phosphorylation decreases phosphorylation |
ISO EXP |
diallyl trisulfide results in decreased expression of MAPK3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein] diallyl trisulfide results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 PMID:29087013 More...
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of MCL1 protein |
CTD |
PMID:28571773 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression increases degradation |
ISO |
diallyl trisulfide results in decreased expression of MDM2 protein diallyl trisulfide results in increased degradation of MDM2 protein |
CTD |
PMID:23754639 PMID:24415872 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mir143 |
microRNA 143 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of MIR143 mRNA |
CTD |
PMID:23430952 |
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NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
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G |
Mir145 |
microRNA 145 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of MIR145 mRNA |
CTD |
PMID:23430952 |
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NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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G |
Mir200b |
microRNA 200b |
increases expression |
ISO |
diallyl trisulfide results in increased expression of MIR200B mRNA |
CTD |
PMID:23430952 |
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NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
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G |
Mir200c |
microRNA 200c |
increases expression |
ISO |
diallyl trisulfide results in increased expression of MIR200C mRNA |
CTD |
PMID:23430952 |
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NCBI chr 4:157,523,679...157,523,747
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G |
Mir21 |
microRNA 21 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of MIR21 mRNA |
CTD |
PMID:23430952 |
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NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mir221 |
microRNA 221 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of MIR221 mRNA |
CTD |
PMID:23663050 |
|
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions decreases activity decreases expression |
ISO |
diallyl trisulfide results in decreased expression of and results in decreased activity of MMP2 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein] diallyl trisulfide results in decreased expression of MMP2 mRNA; diallyl trisulfide results in decreased expression of MMP2 protein |
CTD |
PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 PMID:28574600 PMID:28741790 PMID:30396169 More...
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp7 |
matrix metallopeptidase 7 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of MMP7 protein |
CTD |
PMID:21695758 |
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NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions affects expression decreases activity decreases expression |
ISO |
diallyl trisulfide results in decreased expression of and results in decreased activity of MMP9 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein] diallyl trisulfide affects the expression of MMP9 protein diallyl trisulfide results in decreased expression of MMP9 mRNA; diallyl trisulfide results in decreased expression of MMP9 protein |
CTD |
PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 PMID:28741790 PMID:30396169 More...
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mtor |
mechanistic target of rapamycin kinase |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of MTOR protein |
CTD |
PMID:23754639 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of MYC mRNA; diallyl trisulfide results in decreased expression of MYC protein FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA] |
CTD |
PMID:23754639 PMID:27129776 PMID:29626521 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] |
CTD |
PMID:25500681 |
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NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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G |
Nanog |
Nanog homeobox |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of NANOG protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein] |
CTD |
PMID:29626521 |
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NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
decreases expression |
EXP |
diallyl trisulfide results in decreased expression of NCF1 protein |
CTD |
PMID:29087013 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ndrg1 |
N-myc downstream regulated 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of NDRG1 mRNA |
CTD |
PMID:17937621 |
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NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression increases activity increases localization |
EXP ISO |
[diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; diallyl trisulfide promotes the reaction [Glucose results in increased expression of and affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein] diallyl trisulfide results in increased expression of NFE2L2 mRNA; diallyl trisulfide results in increased expression of NFE2L2 protein diallyl trisulfide results in increased activity of NFE2L2 protein Acetylcysteine inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; Dithiothreitol inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein] diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] diallyl trisulfide results in increased localization of NFE2L2 protein |
CTD |
PMID:18768114 PMID:20237067 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 More...
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
decreases phosphorylation decreases degradation increases phosphorylation increases expression |
ISO |
diallyl trisulfide results in decreased phosphorylation of NFKBIA protein diallyl trisulfide results in decreased degradation of NFKBIA protein diallyl trisulfide results in increased phosphorylation of NFKBIA protein diallyl trisulfide results in increased expression of NFKBIA mRNA; diallyl trisulfide results in increased expression of NFKBIA protein |
CTD |
PMID:23663050 PMID:24788927 PMID:25205294 PMID:25927362 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
affects expression multiple interactions |
ISO |
diallyl trisulfide affects the expression of NOS2 protein diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] |
CTD |
PMID:21695758 PMID:25500681 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions decreases degradation increases phosphorylation increases expression |
ISO |
diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein]; wortmannin inhibits the reaction [diallyl trisulfide results in increased phosphorylation of NOS3 protein] diallyl trisulfide results in decreased degradation of NOS3 protein diallyl trisulfide results in increased expression of NOS3 protein |
CTD |
PMID:20229525 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch1 |
notch receptor 1 |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of NOTCH1 mRNA; diallyl trisulfide results in decreased expression of NOTCH1 protein NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein] |
CTD |
PMID:23430952 |
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NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
EXP ISO |
diallyl trisulfide results in increased expression of NQO1 mRNA diallyl trisulfide results in increased expression of NQO1 mRNA; diallyl trisulfide results in increased expression of NQO1 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein] |
CTD |
PMID:20650352 PMID:24489685 PMID:30317421 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nucb1 |
nucleobindin 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of NUCB1 protein |
CTD |
PMID:19550292 |
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NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
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G |
Ogdh |
oxoglutarate dehydrogenase |
multiple interactions |
EXP |
diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of OGDH protein] |
CTD |
PMID:24295472 |
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NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
diallyl trisulfide results in increased cleavage of PARP1 protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein] |
CTD |
PMID:20055834 PMID:22578287 PMID:25205294 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pcna |
proliferating cell nuclear antigen |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of PCNA protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein] |
CTD |
PMID:29626521 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pgk1 |
phosphoglycerate kinase 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of PGK1 protein |
CTD |
PMID:16344271 |
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NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
EXP |
PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein] |
CTD |
PMID:25896937 |
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NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
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G |
Plaur |
plasminogen activator, urokinase receptor |
affects expression |
ISO |
diallyl trisulfide affects the expression of PLAUR protein |
CTD |
PMID:27129776 |
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NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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G |
Plin3 |
perilipin 3 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of PLIN3 protein |
CTD |
PMID:16344271 |
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NCBI chr 9:1,111,178...1,123,117
Ensembl chr 9:1,102,366...1,123,147
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G |
Pou5f1 |
POU class 5 homeobox 1 |
multiple interactions |
ISO |
[diallyl trisulfide results in increased abundance of Hydrogen Sulfide] which results in increased expression of POU5F1 mRNA |
CTD |
PMID:33180827 |
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NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression |
ISO |
diallyl trisulfide results in increased expression of PPARA mRNA |
CTD |
PMID:16382202 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases activity multiple interactions decreases expression |
ISO |
diallyl trisulfide results in decreased activity of PPARG protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in decreased expression of and results in decreased activity of PPARG protein]; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein] diallyl trisulfide results in decreased expression of PPARG mRNA; diallyl trisulfide results in decreased expression of PPARG protein |
CTD |
PMID:22137902 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Prom1 |
prominin 1 |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of PROM1 protein diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein] |
CTD |
PMID:29626521 |
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NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
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G |
Psma1 |
proteasome 20S subunit alpha 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of PSMA1 protein |
CTD |
PMID:19550292 |
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NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
affects expression decreases expression multiple interactions |
ISO |
diallyl trisulfide affects the expression of PTGS2 protein diallyl trisulfide results in decreased expression of PTGS2 mRNA diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]] |
CTD |
PMID:15523159 PMID:21695758 PMID:25500681 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ptk2 |
protein tyrosine kinase 2 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of PTK2 protein; diallyl trisulfide results in decreased expression of PTK2 protein modified form |
CTD |
PMID:28741790 |
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NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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G |
Rbp1 |
retinol binding protein 1 |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of RBP1 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in increased expression of RBP1 protein] |
CTD |
PMID:28157488 |
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NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases expression |
ISO EXP |
diallyl trisulfide results in decreased phosphorylation of and affects the localization of RELA protein diallyl trisulfide results in decreased expression of RELA mRNA; diallyl trisulfide results in decreased expression of RELA protein diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of RELA protein] |
CTD |
PMID:24788927 PMID:25927362 PMID:29087013 PMID:30396169 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
S100a11 |
S100 calcium binding protein A11 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of S100A11 protein |
CTD |
PMID:16344271 |
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NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044
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G |
S100a6 |
S100 calcium binding protein A6 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of S100A6 mRNA |
CTD |
PMID:11925593 |
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NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
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G |
Serpine2 |
serpin family E member 2 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of SERPINE2 mRNA |
CTD |
PMID:11925594 |
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NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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G |
Shc1 |
SHC adaptor protein 1 |
increases phosphorylation multiple interactions decreases response to substance affects response to substance |
ISO |
diallyl trisulfide results in increased phosphorylation of SHC1 protein pyrazolanthrone inhibits the reaction [diallyl trisulfide results in increased phosphorylation of SHC1 protein]; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein] SHC1 protein modified form results in decreased susceptibility to diallyl trisulfide SHC1 protein affects the susceptibility to diallyl trisulfide |
CTD |
PMID:21616139 PMID:22020565 |
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NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
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G |
Snai1 |
snail family transcriptional repressor 1 |
multiple interactions decreases expression |
ISO |
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein] |
CTD |
PMID:27566995 PMID:28574600 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snai2 |
snail family transcriptional repressor 2 |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI2 protein] |
CTD |
PMID:28574600 |
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NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
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G |
Sod1 |
superoxide dismutase 1 |
increases expression |
EXP |
diallyl trisulfide results in increased expression of SOD1 protein |
CTD |
PMID:23453443 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
EXP ISO |
diallyl trisulfide results in increased expression of SOD2 protein SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein] |
CTD |
PMID:23412769 PMID:23453443 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Srsf1 |
serine and arginine rich splicing factor 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of SRSF1 protein |
CTD |
PMID:16344271 |
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NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
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G |
Tagln2 |
transgelin 2 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of TAGLN2 protein |
CTD |
PMID:16344271 |
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NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
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G |
Tardbp |
TAR DNA binding protein |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of TARDBP protein |
CTD |
PMID:30317421 |
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NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of and results in decreased secretion of TGFB1 protein |
CTD |
PMID:20979868 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of TIMP1 mRNA; diallyl trisulfide results in increased expression of TIMP1 protein |
CTD |
PMID:24084732 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
increases expression |
ISO |
diallyl trisulfide results in increased expression of TIMP2 mRNA; diallyl trisulfide results in increased expression of TIMP2 protein |
CTD |
PMID:24084732 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] |
CTD |
PMID:25500681 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
decreases secretion decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased secretion of TNF protein diallyl trisulfide results in decreased expression of TNF mRNA [ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] |
CTD |
PMID:16110831 PMID:17448272 PMID:25500681 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfsf10 |
TNF superfamily member 10 |
increases response to substance multiple interactions |
ISO |
diallyl trisulfide results in increased susceptibility to TNFSF10 protein [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein |
CTD |
PMID:28571773 |
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NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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G |
Tp53 |
tumor protein p53 |
affects localization increases expression multiple interactions |
ISO |
diallyl trisulfide affects the localization of TP53 protein diallyl trisulfide results in increased expression of TP53 mRNA; diallyl trisulfide results in increased expression of TP53 protein diallyl trisulfide results in increased expression of and affects the localization of TP53 protein |
CTD |
PMID:19823037 PMID:23754639 PMID:24415872 PMID:28571773 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tpt1 |
tumor protein, translationally-controlled 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of TPT1 protein |
CTD |
PMID:16344271 |
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NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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G |
Twist1 |
twist family bHLH transcription factor 1 |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of TWIST1 protein LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein] |
CTD |
PMID:27566995 |
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NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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G |
Txn1 |
thioredoxin 1 |
decreases expression multiple interactions decreases reduction |
ISO |
diallyl trisulfide results in decreased expression of TXN protein TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein] diallyl trisulfide results in decreased reduction of TXN protein |
CTD |
PMID:28574600 PMID:30396169 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
ISO |
diallyl trisulfide results in increased expression of TXNIP protein TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein] |
CTD |
PMID:30396169 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of UCHL1 protein |
CTD |
PMID:19550292 |
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NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases expression |
EXP |
diallyl trisulfide results in increased expression of UGT1A1 mRNA |
CTD |
PMID:20650352 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Vdac1 |
voltage-dependent anion channel 1 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of VDAC1 protein |
CTD |
PMID:16344271 |
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NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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G |
Vdac2 |
voltage-dependent anion channel 2 |
decreases expression |
ISO |
diallyl trisulfide results in decreased expression of VDAC2 protein |
CTD |
PMID:16344271 |
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NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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G |
Vegfa |
vascular endothelial growth factor A |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of VEGFA mRNA; diallyl trisulfide results in decreased expression of VEGFA protein diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; diallyl trisulfide results in decreased expression of and results in decreased secretion of VEGFA protein; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein] |
CTD |
PMID:23430952 PMID:23754639 PMID:28574600 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
decreases expression multiple interactions |
ISO |
diallyl trisulfide results in decreased expression of VIM protein SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein] |
CTD |
PMID:19550292 PMID:23412769 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Xiap |
X-linked inhibitor of apoptosis |
increases degradation decreases expression multiple interactions decreases response to substance |
ISO |
diallyl trisulfide results in increased degradation of XIAP protein diallyl trisulfide results in decreased expression of XIAP protein Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein] XIAP protein results in decreased susceptibility to diallyl trisulfide |
CTD |
PMID:21411500 PMID:22578287 PMID:25205294 |
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NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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