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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:diallyl trisulfide
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Accession:CHEBI:78492 term browser browse the term
Definition:An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity
Synonyms:exact_synonym: diallyltrisulfane
 related_synonym: (CH2=CHCH2S)2S;   DATS;   Formula=C6H10S3;   InChI=1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2;   InChIKey=UBAXRAHSPKWNCX-UHFFFAOYSA-N;   SMILES=C=CCSSSCC=C;   allyl trisulfide;   di-2-propenyl trisulfide
 xref: CAS:2050-87-5;   HMDB:HMDB0031154
 xref_mesh: MESH:C042577
 xref: PMID:10757551;   PMID:11020449;   PMID:22020565;   PMID:22137902;   PMID:22143535;   PMID:22525868;   PMID:22578287;   PMID:22595511;   PMID:22736270;   PMID:22919419;   PMID:23073793;   PMID:23139364;   PMID:23412769;   PMID:23430952;   PMID:23453443;   PMID:23811270;   PMID:23859039;   PMID:24084732;   PMID:24295472;   PMID:24309133;   PMID:24415872;   PMID:24440170;   PMID:24460275;   PMID:24487688;   PMID:24489685;   PMID:24557053;   PMID:24788927;   PMID:3791995;   PMID:5135721;   PMID:8024350;   PMID:9654398;   Reaxys:1745734;   Wikipedia:Diallyl_trisulfide


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diallyl trisulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression		 ISO diallyl trisulfide results in increased expression of ABCB1 mRNA
diallyl trisulfide results in decreased expression of ABCB1 protein		 CTD PMID:22397993 PMID:24788927 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO diallyl trisulfide results in increased expression of ABCC1 mRNA CTD PMID:22397993 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO diallyl trisulfide results in decreased expression of ABCC3 mRNA CTD PMID:22397993 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
decreases expression		 ISO diallyl trisulfide results in increased expression of ABCC4 mRNA
diallyl trisulfide results in decreased expression of ABCC4 mRNA		 CTD PMID:22397993 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO diallyl trisulfide results in increased expression of ABCC6 mRNA CTD PMID:22397993 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of ACTA2 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of ACTA2 protein] CTD PMID:28157488 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actg1 actin, gamma 1 decreases expression ISO diallyl trisulfide results in decreased expression of ACTG1 protein CTD PMID:19550292 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 		JBrowse link
G Ak2 adenylate kinase 2 increases expression ISO diallyl trisulfide results in increased expression of AK2 protein CTD PMID:16344271 NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression		 EXP
ISO		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]
diallyl trisulfide results in decreased phosphorylation of AKT1 protein
diallyl trisulfide results in increased phosphorylation of AKT1 protein
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; pyrazolanthrone inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]
diallyl trisulfide results in decreased expression of AKT1 mRNA; diallyl trisulfide results in decreased expression of AKT1 protein		 CTD PMID:19823037 PMID:22020565 PMID:23453443 PMID:23663050 PMID:23754639 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases activity
decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased activity of ALDH1 protein
diallyl trisulfide results in decreased expression of ALDH1A1 protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased activity of ALDH1 protein]		 CTD PMID:27129776 PMID:29626521 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO diallyl trisulfide results in increased expression of ALPL protein CTD PMID:19550292 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] CTD PMID:28574600 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Anxa1 annexin A1 increases expression ISO diallyl trisulfide results in increased expression of ANXA1 mRNA; diallyl trisulfide results in increased expression of ANXA1 protein CTD PMID:16344271 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Ar androgen receptor decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of AR mRNA; diallyl trisulfide results in decreased expression of AR protein
diallyl trisulfide inhibits the reaction [Metribolone affects the localization of AR protein]		 CTD PMID:19622577 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression
increases expression		 ISO diallyl trisulfide results in decreased expression of ATP5PD protein
diallyl trisulfide results in increased expression of ATP5PD protein		 CTD PMID:16344271 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation ISO diallyl trisulfide results in decreased phosphorylation of BAD protein CTD PMID:27566995 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
multiple interactions
increases activity		 ISO diallyl trisulfide results in increased expression of BAK1 protein
SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]		 CTD PMID:17513609 PMID:23412769 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
increases activity		 ISO
EXP		 diallyl trisulfide results in increased expression of BAX mRNA; diallyl trisulfide results in increased expression of BAX protein
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of BAX protein]
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of BAX protein]
diallyl trisulfide results in increased activity of BAX protein		 CTD PMID:19823037 PMID:23412769 PMID:23754639 PMID:24415872 PMID:24460275 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO diallyl trisulfide results in increased expression of BBC3 mRNA; diallyl trisulfide results in increased expression of BBC3 protein CTD PMID:24460275 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO
EXP		 diallyl trisulfide results in decreased expression of BCL2; diallyl trisulfide results in decreased expression of BCL2 mRNA; diallyl trisulfide results in decreased expression of BCL2 protein
diallyl trisulfide inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]
Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]		 CTD PMID:17513609 PMID:19823037 PMID:20055834 PMID:22578287 PMID:22595511 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO diallyl trisulfide results in decreased expression of BCL2L1 protein CTD PMID:17513609 PMID:20055834 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO diallyl trisulfide results in decreased expression of BID protein CTD PMID:22578287 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression
decreases expression		 ISO diallyl trisulfide results in increased expression of BIRC2 protein
diallyl trisulfide results in decreased expression of BIRC2 protein		 CTD PMID:21411500 PMID:22578287 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
decreases expression		 ISO diallyl trisulfide results in increased expression of BIRC5 protein
diallyl trisulfide results in decreased expression of BIRC5 protein
diallyl trisulfide results in increased expression of BIRC5 mRNA; diallyl trisulfide results in increased expression of BIRC5 protein		 CTD PMID:21411500 PMID:23754639 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger affects expression ISO diallyl trisulfide affects the expression of BMI1 protein CTD PMID:27129776 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Btf3 basic transcription factor 3 increases expression ISO diallyl trisulfide results in increased expression of BTF3 protein CTD PMID:16344271 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879 		JBrowse link
G Calr calreticulin increases expression ISO diallyl trisulfide results in increased expression of CALR protein CTD PMID:19550292 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression ISO diallyl trisulfide results in decreased expression of CAPZA1 protein CTD PMID:16344271 NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression		 ISO
EXP		 diallyl trisulfide results in increased activity of CASP3 protein
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]
diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]
diallyl trisulfide results in increased expression of CASP3 mRNA		 CTD PMID:20055834 PMID:21574149 PMID:22578287 PMID:22595511 PMID:23453443 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
increases cleavage		 ISO diallyl trisulfide results in increased activity of CASP8 protein
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein]		 CTD PMID:22578287 PMID:22595511 PMID:28571773 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity		 ISO [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein]
diallyl trisulfide results in increased activity of CASP9 protein		 CTD PMID:20055834 PMID:22578287 PMID:22595511 PMID:28571773 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of CAT protein] CTD PMID:24295472 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 multiple interactions ISO diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein] CTD PMID:20229525 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccnb1 cyclin B1 increases expression
affects localization
multiple interactions		 ISO diallyl trisulfide results in increased expression of CCNB1 protein
diallyl trisulfide affects the localization of CCNB1 protein
diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]		 CTD PMID:19823037 PMID:20143254 PMID:24415872 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression		 ISO diallyl trisulfide results in decreased expression of CCND1 mRNA; diallyl trisulfide results in decreased expression of CCND1 protein
diallyl trisulfide results in increased expression of CCND1 mRNA; diallyl trisulfide results in increased expression of CCND1 protein		 CTD PMID:14693049 PMID:19823037 PMID:23430952 PMID:24415872 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
decreases expression		 ISO diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDC25C protein; diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein; EUK-134 inhibits the reaction [diallyl trisulfide results in increased phosphorylation of and results in increased degradation of CDC25C protein]
diallyl trisulfide results in decreased expression of CDC25C protein		 CTD PMID:16707465 PMID:20143254 PMID:23754639 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression		 ISO SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein] CTD PMID:23412769 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
affects localization		 ISO diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]; diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDK1 protein
diallyl trisulfide affects the localization of CDK1 protein		 CTD PMID:20143254 PMID:23754639 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO diallyl trisulfide results in increased expression of CDKN1A mRNA; diallyl trisulfide results in increased expression of CDKN1A protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]		 CTD PMID:16222732 PMID:17937621 PMID:23754639 PMID:24415872 PMID:29626521 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO diallyl trisulfide results in increased expression of CDKN1B protein CTD PMID:14693049 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of CEBPA mRNA; diallyl trisulfide results in decreased expression of CEBPA protein
[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]		 CTD PMID:22137902 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression		 ISO [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]
diallyl trisulfide results in decreased expression of CEBPB mRNA; diallyl trisulfide results in decreased expression of CEBPB protein		 CTD PMID:22137902 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cfl1 cofilin 1 decreases expression ISO diallyl trisulfide results in decreased expression of CFL1 protein CTD PMID:16344271 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO diallyl trisulfide results in decreased expression of CFLAR protein CTD PMID:25205294 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cldn1 claudin 1 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN1 mRNA; diallyl trisulfide results in decreased expression of CLDN1 protein CTD PMID:24084732 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn2 claudin 2 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN2 mRNA; diallyl trisulfide results in decreased expression of CLDN2 protein CTD PMID:24084732 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cldn3 claudin 3 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN3 mRNA; diallyl trisulfide results in decreased expression of CLDN3 protein CTD PMID:24084732 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Cldn4 claudin 4 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN4 mRNA; diallyl trisulfide results in decreased expression of CLDN4 protein CTD PMID:24084732 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Cldn5 claudin 5 decreases expression ISO diallyl trisulfide results in decreased expression of CLDN5 mRNA; diallyl trisulfide results in decreased expression of CLDN5 protein CTD PMID:24084732 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cstb cystatin B decreases expression ISO diallyl trisulfide results in decreased expression of CSTB protein CTD PMID:16344271 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Ctnnb1 catenin beta 1 increases cleavage
decreases expression
multiple interactions
decreases phosphorylation		 ISO diallyl trisulfide results in increased cleavage of CTNNB1 protein
diallyl trisulfide results in decreased expression of CTNNB1 protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of ALDH1A1 protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]; diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein]
diallyl trisulfide results in decreased phosphorylation of CTNNB1 protein		 CTD PMID:22578287 PMID:23663050 PMID:29626521 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cul3 cullin 3 decreases expression EXP diallyl trisulfide results in decreased expression of CUL3 protein CTD PMID:23453443 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBA protein] CTD PMID:29087013 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP diallyl trisulfide inhibits the reaction [Doxorubicin results in increased expression of CYBB protein] CTD PMID:29087013 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein] CTD PMID:31115753 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein] CTD PMID:28115069 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein] CTD PMID:28115069 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP diallyl trisulfide inhibits the reaction [n-hexane results in increased activity of CYP2B1 protein] CTD PMID:28115069 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions		 EXP diallyl trisulfide results in decreased expression of CYP2E1 protein
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]		 CTD PMID:28115069 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO diallyl trisulfide results in decreased expression of CYP7A1 mRNA CTD PMID:16382202 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dach1 dachshund family transcription factor 1 increases expression
multiple interactions		 ISO diallyl trisulfide results in increased expression of DACH1 mRNA
FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA]		 CTD PMID:27129776 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922 		JBrowse link
G Ddt D-dopachrome tautomerase decreases expression ISO diallyl trisulfide results in decreased expression of DDT protein CTD PMID:16344271 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Des desmin multiple interactions ISO diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of DES protein] CTD PMID:28157488 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases degradation ISO diallyl trisulfide results in increased degradation of DFFA protein CTD PMID:23754639 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633 		JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 decreases expression ISO diallyl trisulfide results in decreased expression of DNAJC27 protein CTD PMID:19550292 NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO diallyl trisulfide inhibits the reaction [Glucose results in increased expression of DNM1L protein] CTD PMID:31115753 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dynlrb1 dynein light chain roadblock-type 1 decreases expression ISO diallyl trisulfide results in decreased expression of DYNLRB1 protein CTD PMID:19550292 NCBI chr 3:143,742,427...143,764,227
Ensembl chr 3:143,742,586...143,764,227 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO diallyl trisulfide results in decreased expression of EGFR protein CTD PMID:23754639 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif4h eukaryotic translation initiation factor 4H decreases expression ISO diallyl trisulfide results in decreased expression of EIF4H protein CTD PMID:16344271 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876 		JBrowse link
G Eno1 enolase 1 increases expression ISO diallyl trisulfide results in increased expression of ENO1 protein CTD PMID:16344271 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP diallyl trisulfide results in increased expression of EPHX1 mRNA CTD PMID:20650352 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO diallyl trisulfide results in increased expression of FAS mRNA; diallyl trisulfide results in increased expression of FAS protein CTD PMID:19823037 PMID:24415872 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN CTD PMID:22137902 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Folr1 folate receptor alpha increases expression ISO diallyl trisulfide results in increased expression of FOLR1 mRNA CTD PMID:11925593 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects localization ISO diallyl trisulfide affects the localization of FOS protein CTD PMID:25927362 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO diallyl trisulfide results in decreased expression of FOXP3 mRNA CTD PMID:20979868 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Foxq1 forkhead box Q1 multiple interactions
decreases expression		 ISO diallyl trisulfide results in decreased expression of and affects the localization of FOXQ1 protein; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased activity of ALDH1 protein]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]; FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA]
diallyl trisulfide results in decreased expression of FOXQ1 mRNA		 CTD PMID:27129776 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein CTD PMID:16707465 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein]; diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] CTD PMID:16707465 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725 		JBrowse link
G Ftmt ferritin mitochondrial multiple interactions
decreases expression		 ISO [diallyl trisulfide results in decreased expression of FTMT protein] which results in increased abundance of Iron; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein] CTD PMID:21616139 NCBI chr18:45,758,874...45,760,123
Ensembl chr18:45,758,874...45,760,123 		JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO diallyl trisulfide results in increased expression of FUBP1 protein CTD PMID:16344271 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO diallyl trisulfide results in increased expression of GADD45A mRNA CTD PMID:17937621 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO diallyl trisulfide results in decreased expression of GAPDH protein CTD PMID:16344271 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
increases phosphorylation		 EXP
ISO		 diallyl trisulfide results in decreased expression of GSK3B protein
diallyl trisulfide results in decreased expression of GSK3B protein modified form
diallyl trisulfide results in increased phosphorylation of GSK3B protein		 CTD PMID:23453443 PMID:23663050 PMID:29626521 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP diallyl trisulfide results in increased expression of GSTA5 mRNA CTD PMID:20650352 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 diallyl trisulfide results in decreased expression of GSTP1 mRNA; diallyl trisulfide results in decreased expression of GSTP1 protein
diallyl trisulfide results in increased expression of GSTP1 mRNA
[diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; [diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and results in increased activity of GSTP1 protein		 CTD PMID:16344271 PMID:20237067 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO diallyl trisulfide results in decreased expression of HES1 mRNA CTD PMID:23430952 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 decreases expression ISO diallyl trisulfide results in decreased expression of HEY1 mRNA CTD PMID:23430952 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 decreases expression ISO diallyl trisulfide results in decreased expression of HEY2 mRNA CTD PMID:23430952 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression		 ISO diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
diallyl trisulfide results in decreased expression of HIF1A protein		 CTD PMID:28574600 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein]; [diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
diallyl trisulfide results in increased expression of HMOX1 mRNA; diallyl trisulfide results in increased expression of HMOX1 protein		 CTD PMID:23412769 PMID:23453443 PMID:24489685 PMID:25896937 PMID:30317421 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO diallyl trisulfide results in increased expression of HNF4A mRNA CTD PMID:16382202 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO diallyl trisulfide results in decreased expression of HNRNPA2B1 protein CTD PMID:16344271 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like increases expression ISO diallyl trisulfide results in increased expression of HNRNPDL protein CTD PMID:16344271 NCBI chr14:9,558,079...9,563,654
Ensembl chr14:9,557,425...9,562,506 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 increases expression ISO diallyl trisulfide results in increased expression of HNRNPH1 protein CTD PMID:16344271 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO diallyl trisulfide results in decreased expression of HSPA5 protein CTD PMID:19550292 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO diallyl trisulfide results in decreased expression of HSPA8 protein CTD PMID:19550292 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO diallyl trisulfide results in decreased expression of HSPA9 protein CTD PMID:19550292 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO diallyl trisulfide results in decreased expression of HSPD1 protein CTD PMID:19550292 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO diallyl trisulfide results in decreased expression of HYOU1 protein CTD PMID:19550292 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO diallyl trisulfide results in decreased expression of and results in decreased secretion of IL10 protein CTD PMID:20979868 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]] CTD PMID:25500681 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression ISO diallyl trisulfide results in increased expression of INA protein CTD PMID:19550292 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330 		JBrowse link
G Itga4 integrin subunit alpha 4 decreases expression ISO diallyl trisulfide results in decreased expression of ITGA4 protein CTD PMID:28741790 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO diallyl trisulfide results in decreased expression of ITGA5 protein CTD PMID:28741790 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO diallyl trisulfide results in decreased expression of ITGAV protein CTD PMID:28741790 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO diallyl trisulfide results in decreased expression of ITGB1 protein CTD PMID:28741790 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression ISO diallyl trisulfide results in decreased expression of ITGB3 protein CTD PMID:28741790 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO diallyl trisulfide results in decreased expression of ITGB4 protein CTD PMID:28741790 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation
affects localization
increases activity
increases expression
multiple interactions		 ISO
EXP		 diallyl trisulfide results in increased phosphorylation of JUN protein
diallyl trisulfide affects the localization of JUN protein
diallyl trisulfide results in increased activity of JUN protein
diallyl trisulfide results in increased expression of JUN protein
[diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]
MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein]		 CTD PMID:16707465 PMID:20237067 PMID:25927362 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases activity ISO diallyl trisulfide results in decreased activity of KCNA5 protein CTD PMID:23272117 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 multiple interactions ISO diallyl trisulfide binds to and results in decreased activity of KCND3 protein CTD PMID:23272117 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO diallyl trisulfide results in decreased expression of and results in decreased activity of KCNH2 protein
diallyl trisulfide results in decreased activity of KCNH2 protein		 CTD PMID:23272117 PMID:24504171 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
affects binding
multiple interactions		 EXP
ISO		 diallyl trisulfide results in decreased expression of KEAP1 protein
diallyl trisulfide binds to KEAP1 protein
diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein]		 CTD PMID:23453443 PMID:24489685 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO diallyl trisulfide results in increased expression of KIT protein CTD PMID:23663050 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Krt10 keratin 10 increases expression ISO diallyl trisulfide results in increased expression of KRT10 protein CTD PMID:19550292 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701 		JBrowse link
G Krt8 keratin 8 decreases expression ISO diallyl trisulfide results in decreased expression of KRT8 protein CTD PMID:16344271 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G L1cam L1 cell adhesion molecule multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM mRNA]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of L1CAM protein] CTD PMID:28574600 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 increases expression ISO diallyl trisulfide results in increased expression of LAMTOR5 mRNA CTD PMID:11925594 NCBI chr 2:194,900,038...194,905,394
Ensembl chr 2:194,900,038...194,905,395 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
decreases response to substance
decreases expression		 ISO LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]
LDHA protein results in decreased susceptibility to diallyl trisulfide
diallyl trisulfide results in decreased expression of LDHA protein		 CTD PMID:27566995 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Lox lysyl oxidase multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:28574600 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Loxl4 lysyl oxidase-like 4 multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOXL4 mRNA] CTD PMID:28574600 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO MAP2K4 protein affects the reaction [diallyl trisulfide results in increased abundance of Reactive Oxygen Species]; MAP2K4 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein] CTD PMID:16707465 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 affects expression
multiple interactions		 ISO diallyl trisulfide affects the expression of MAP2K7 protein
MAP2K7 protein affects the reaction [diallyl trisulfide results in increased degradation of FTL protein]; MAP2K7 protein affects the reaction [diallyl trisulfide results in increased phosphorylation of JUN protein]		 CTD PMID:16707465 PMID:21695758 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 affects expression ISO diallyl trisulfide affects the expression of MAP3K3 protein CTD PMID:21695758 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein]
diallyl trisulfide results in decreased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK1 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]
diallyl trisulfide results in decreased expression of MAPK1 protein		 CTD PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
decreases phosphorylation
increases phosphorylation
multiple interactions		 ISO
EXP		 diallyl trisulfide results in decreased expression of MAPK3 protein
diallyl trisulfide results in decreased phosphorylation of MAPK3 protein
diallyl trisulfide results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in increased phosphorylation of MAPK3 protein]; diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]		 CTD PMID:17263507 PMID:21695758 PMID:22137902 PMID:25205294 PMID:25927362 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO diallyl trisulfide results in decreased expression of MCL1 protein CTD PMID:28571773 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression
increases degradation		 ISO diallyl trisulfide results in decreased expression of MDM2 protein
diallyl trisulfide results in increased degradation of MDM2 protein		 CTD PMID:23754639 PMID:24415872 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mir143 microRNA 143 increases expression ISO diallyl trisulfide results in increased expression of MIR143 mRNA CTD PMID:23430952 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir145 microRNA 145 increases expression ISO diallyl trisulfide results in increased expression of MIR145 mRNA CTD PMID:23430952 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir200b microRNA 200b increases expression ISO diallyl trisulfide results in increased expression of MIR200B mRNA CTD PMID:23430952 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir200c microRNA 200c increases expression ISO diallyl trisulfide results in increased expression of MIR200C mRNA CTD PMID:23430952 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir21 microRNA 21 decreases expression ISO diallyl trisulfide results in decreased expression of MIR21 mRNA CTD PMID:23430952 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir221 microRNA 221 decreases expression ISO diallyl trisulfide results in decreased expression of MIR221 mRNA CTD PMID:23663050 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
decreases activity		 ISO diallyl trisulfide results in decreased expression of and results in decreased activity of MMP2 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]
diallyl trisulfide results in decreased expression of MMP2 mRNA; diallyl trisulfide results in decreased expression of MMP2 protein		 CTD PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 More... NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO diallyl trisulfide results in decreased expression of MMP7 protein CTD PMID:21695758 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
decreases activity
affects expression		 ISO diallyl trisulfide results in decreased expression of and results in decreased activity of MMP9 protein; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]
diallyl trisulfide results in decreased expression of MMP9 mRNA; diallyl trisulfide results in decreased expression of MMP9 protein
diallyl trisulfide affects the expression of MMP9 protein		 CTD PMID:21695758 PMID:23430952 PMID:24084732 PMID:25927362 PMID:27566995 More... NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO diallyl trisulfide results in decreased expression of MTOR protein CTD PMID:23754639 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of MYC mRNA; diallyl trisulfide results in decreased expression of MYC protein
FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]		 CTD PMID:23754639 PMID:27129776 PMID:29626521 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] CTD PMID:25500681 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nanog Nanog homeobox decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of NANOG protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of NANOG protein]		 CTD PMID:29626521 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 decreases expression EXP diallyl trisulfide results in decreased expression of NCF1 protein CTD PMID:29087013 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO diallyl trisulfide results in increased expression of NDRG1 mRNA CTD PMID:17937621 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases localization
increases activity
increases expression		 EXP
ISO		 [diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; diallyl trisulfide promotes the reaction [Glucose results in increased expression of and affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein]
diallyl trisulfide results in increased localization of NFE2L2 protein
diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]
Acetylcysteine inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; diallyl trisulfide promotes the reaction [KEAP1 mutant form affects the localization of NFE2L2 protein]; diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein; Dithiothreitol inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]
diallyl trisulfide results in increased activity of NFE2L2 protein
diallyl trisulfide results in increased expression of NFE2L2 mRNA; diallyl trisulfide results in increased expression of NFE2L2 protein		 CTD PMID:18768114 PMID:20237067 PMID:23453443 PMID:24489685 PMID:25896937 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases phosphorylation
increases expression
increases phosphorylation
decreases degradation		 ISO diallyl trisulfide results in decreased phosphorylation of NFKBIA protein
diallyl trisulfide results in increased expression of NFKBIA mRNA; diallyl trisulfide results in increased expression of NFKBIA protein
diallyl trisulfide results in increased phosphorylation of NFKBIA protein
diallyl trisulfide results in decreased degradation of NFKBIA protein		 CTD PMID:23663050 PMID:24788927 PMID:25205294 PMID:25927362 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 affects expression
multiple interactions		 ISO diallyl trisulfide affects the expression of NOS2 protein
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]		 CTD PMID:21695758 PMID:25500681 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
increases phosphorylation
decreases degradation		 ISO diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein]; wortmannin inhibits the reaction [diallyl trisulfide results in increased phosphorylation of NOS3 protein]
diallyl trisulfide results in increased expression of NOS3 protein
diallyl trisulfide results in decreased degradation of NOS3 protein		 CTD PMID:20229525 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of NOTCH1 mRNA; diallyl trisulfide results in decreased expression of NOTCH1 protein
NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein]		 CTD PMID:23430952 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 EXP
ISO		 diallyl trisulfide results in increased expression of NQO1 mRNA
diallyl trisulfide results in increased expression of NQO1 protein
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]
diallyl trisulfide results in increased expression of NQO1 mRNA; diallyl trisulfide results in increased expression of NQO1 protein		 CTD PMID:20650352 PMID:24489685 PMID:30317421 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nucb1 nucleobindin 1 decreases expression ISO diallyl trisulfide results in decreased expression of NUCB1 protein CTD PMID:19550292 NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220 		JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of OGDH protein] CTD PMID:24295472 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions		 ISO diallyl trisulfide results in increased cleavage of PARP1 protein
Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]		 CTD PMID:20055834 PMID:22578287 PMID:25205294 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of PCNA protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PCNA protein]		 CTD PMID:29626521 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression ISO diallyl trisulfide results in increased expression of PGK1 protein CTD PMID:16344271 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein] CTD PMID:25896937 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression ISO diallyl trisulfide affects the expression of PLAUR protein CTD PMID:27129776 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plin3 perilipin 3 increases expression ISO diallyl trisulfide results in increased expression of PLIN3 protein CTD PMID:16344271 NCBI chr 9:1,111,178...1,123,117
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [diallyl trisulfide results in increased abundance of Hydrogen Sulfide] which results in increased expression of POU5F1 mRNA CTD PMID:33180827 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO diallyl trisulfide results in increased expression of PPARA mRNA CTD PMID:16382202 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity
decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased activity of PPARG protein
diallyl trisulfide results in decreased expression of PPARG mRNA; diallyl trisulfide results in decreased expression of PPARG protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in decreased expression of and results in decreased activity of PPARG protein]; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]		 CTD PMID:22137902 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prom1 prominin 1 decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of PROM1 protein
diallyl trisulfide inhibits the reaction [CTNNB1 protein results in increased expression of PROM1 protein]		 CTD PMID:29626521 NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression ISO diallyl trisulfide results in decreased expression of PSMA1 protein CTD PMID:19550292 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions
decreases expression		 ISO diallyl trisulfide affects the expression of PTGS2 protein
diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]
diallyl trisulfide results in decreased expression of PTGS2 mRNA		 CTD PMID:15523159 PMID:21695758 PMID:25500681 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO diallyl trisulfide results in decreased expression of PTK2 protein; diallyl trisulfide results in decreased expression of PTK2 protein modified form CTD PMID:28741790 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rbp1 retinol binding protein 1 multiple interactions ISO diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of RBP1 protein]; diallyl trisulfide inhibits the reaction [propargylglycine results in increased expression of RBP1 protein] CTD PMID:28157488 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression		 ISO
EXP		 diallyl trisulfide results in decreased phosphorylation of and affects the localization of RELA protein
diallyl trisulfide inhibits the reaction [Doxorubicin results in increased phosphorylation of RELA protein]
diallyl trisulfide results in decreased expression of RELA mRNA; diallyl trisulfide results in decreased expression of RELA protein		 CTD PMID:24788927 PMID:25927362 PMID:29087013 PMID:30396169 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO diallyl trisulfide results in increased expression of S100A11 protein CTD PMID:16344271 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO diallyl trisulfide results in increased expression of S100A6 mRNA CTD PMID:11925593 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO diallyl trisulfide results in increased expression of SERPINE2 mRNA CTD PMID:11925594 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Shc1 SHC adaptor protein 1 increases phosphorylation
affects response to substance
decreases response to substance
multiple interactions		 ISO diallyl trisulfide results in increased phosphorylation of SHC1 protein
SHC1 protein affects the susceptibility to diallyl trisulfide
SHC1 protein modified form results in decreased susceptibility to diallyl trisulfide
pyrazolanthrone inhibits the reaction [diallyl trisulfide results in increased phosphorylation of SHC1 protein]; SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein]; SHC1 protein modified form inhibits the reaction [diallyl trisulfide results in decreased phosphorylation of AKT1 protein]		 CTD PMID:21616139 PMID:22020565 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
decreases expression		 ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI1 protein]; LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of SNAI1 protein] CTD PMID:27566995 PMID:28574600 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of SNAI2 protein] CTD PMID:28574600 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP diallyl trisulfide results in increased expression of SOD1 protein CTD PMID:23453443 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions		 EXP
ISO		 diallyl trisulfide results in increased expression of SOD2 protein
SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein]; SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]		 CTD PMID:23412769 PMID:23453443 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 increases expression ISO diallyl trisulfide results in increased expression of SRSF1 protein CTD PMID:16344271 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Tagln2 transgelin 2 increases expression ISO diallyl trisulfide results in increased expression of TAGLN2 protein CTD PMID:16344271 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO diallyl trisulfide results in decreased expression of TARDBP protein CTD PMID:30317421 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO diallyl trisulfide results in decreased expression of and results in decreased secretion of TGFB1 protein CTD PMID:20979868 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO diallyl trisulfide results in increased expression of TIMP1 mRNA; diallyl trisulfide results in increased expression of TIMP1 protein CTD PMID:24084732 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO diallyl trisulfide results in increased expression of TIMP2 mRNA; diallyl trisulfide results in increased expression of TIMP2 protein CTD PMID:24084732 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:25500681 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
multiple interactions
decreases expression		 ISO diallyl trisulfide results in decreased secretion of TNF protein
[ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]
diallyl trisulfide results in decreased expression of TNF mRNA		 CTD PMID:16110831 PMID:17448272 PMID:25500681 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance
multiple interactions		 ISO diallyl trisulfide results in increased susceptibility to TNFSF10 protein
[diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP3 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP8 protein; [diallyl trisulfide results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of CASP9 protein		 CTD PMID:28571773 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 affects localization
multiple interactions
increases expression		 ISO diallyl trisulfide affects the localization of TP53 protein
diallyl trisulfide results in increased expression of and affects the localization of TP53 protein
diallyl trisulfide results in increased expression of TP53 mRNA; diallyl trisulfide results in increased expression of TP53 protein		 CTD PMID:19823037 PMID:23754639 PMID:24415872 PMID:28571773 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO diallyl trisulfide results in decreased expression of TPT1 protein CTD PMID:16344271 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of TWIST1 protein
LDHA protein inhibits the reaction [diallyl trisulfide results in decreased expression of TWIST1 protein]		 CTD PMID:27566995 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Txn1 thioredoxin 1 decreases expression
decreases reduction
multiple interactions		 ISO diallyl trisulfide results in decreased expression of TXN protein
diallyl trisulfide results in decreased reduction of TXN protein
TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein]		 CTD PMID:28574600 PMID:30396169 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions		 ISO diallyl trisulfide results in increased expression of TXNIP protein
TXN protein promotes the reaction [diallyl trisulfide results in increased expression of TXNIP protein]		 CTD PMID:30396169 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 decreases expression ISO diallyl trisulfide results in decreased expression of UCHL1 protein CTD PMID:19550292 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP diallyl trisulfide results in increased expression of UGT1A1 mRNA CTD PMID:20650352 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression ISO diallyl trisulfide results in decreased expression of VDAC1 protein CTD PMID:16344271 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 decreases expression ISO diallyl trisulfide results in decreased expression of VDAC2 protein CTD PMID:16344271 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of VEGFA mRNA; diallyl trisulfide results in decreased expression of VEGFA protein
diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; diallyl trisulfide results in decreased expression of and results in decreased secretion of VEGFA protein; NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased secretion of VEGFA protein]		 CTD PMID:23430952 PMID:23754639 PMID:28574600 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vim vimentin decreases expression
multiple interactions		 ISO diallyl trisulfide results in decreased expression of VIM protein
SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]		 CTD PMID:19550292 PMID:23412769 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases degradation
decreases expression
decreases response to substance
multiple interactions		 ISO diallyl trisulfide results in increased degradation of XIAP protein
diallyl trisulfide results in decreased expression of XIAP protein
XIAP protein results in decreased susceptibility to diallyl trisulfide
Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]		 CTD PMID:21411500 PMID:22578287 PMID:25205294 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      application 19737
        anti-inflammatory agent 16331
          diallyl trisulfide 196
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            heteroorganic entity 19544
                              organochalcogen compound 19283
                                organosulfur compound 15419
                                  organic trisulfide 196
                                    diallyl trisulfide 196
paths to the root