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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression |
ISO EXP |
Docosahexaenoic Acids inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA]; Linoleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA]; Oleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] 27-hydroxycholesterol results in increased expression of ABCA1 mRNA; 27-hydroxycholesterol results in increased expression of ABCA1 protein [Fingolimod Hydrochloride results in increased abundance of 27-hydroxycholesterol] which results in increased expression of ABCA1 mRNA |
CTD |
PMID:15148325 PMID:17088262 PMID:18356535 PMID:18841091 PMID:20056921 PMID:28167099 More...
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ABCB1 mRNA |
CTD |
PMID:33880675 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ABCC1 mRNA |
CTD |
PMID:33880675 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ABCG1 protein |
CTD |
PMID:17088262 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of ACTA2 protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein] |
CTD |
PMID:33131013 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
ISO |
27-hydroxycholesterol results in increased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of AKT1 protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:33131013 PMID:33880675 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
27-hydroxycholesterol promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; 27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]] |
CTD |
PMID:20083572 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoe |
apolipoprotein E |
increases expression |
EXP |
27-hydroxycholesterol results in increased expression of APOE mRNA; 27-hydroxycholesterol results in increased expression of APOE protein |
CTD |
PMID:28167099 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions increases expression decreases secretion |
ISO |
27-hydroxycholesterol results in decreased metabolism of and results in decreased secretion of APP protein 27-hydroxycholesterol results in increased expression of APP protein alternative form 27-hydroxycholesterol results in decreased secretion of APP protein alternative form |
CTD |
PMID:15148325 PMID:19126211 PMID:19158428 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arc |
activity-regulated cytoskeleton-associated protein |
decreases expression |
EXP |
27-hydroxycholesterol results in decreased expression of ARC protein |
CTD |
PMID:18503570 |
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NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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G |
Bace1 |
beta-secretase 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of BACE1 protein |
CTD |
PMID:19126211 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Cat |
catalase |
multiple interactions |
ISO |
CAT protein inhibits the reaction [27-hydroxycholesterol results in increased expression of HSPA9 protein] |
CTD |
PMID:33880675 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CCL2 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of CCL2 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CCL2 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression increases secretion |
ISO |
27-hydroxycholesterol results in increased expression of CCL3 mRNA 27-hydroxycholesterol results in increased secretion of CCL3 protein |
CTD |
PMID:24370436 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases secretion increases expression |
ISO |
27-hydroxycholesterol results in increased secretion of CCL4 protein 27-hydroxycholesterol results in increased expression of CCL4 mRNA |
CTD |
PMID:24370436 |
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccn5 |
cellular communication network factor 5 |
multiple interactions increases expression |
ISO |
Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CCN5 mRNA] |
CTD |
PMID:17872378 |
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NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
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G |
Cd36 |
CD36 molecule |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of CD36 mRNA [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CD36 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of CD36 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CD36 mRNA]; Quercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of CD36 mRNA]; Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CD36 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdh5 |
cadherin 5 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein] 27-hydroxycholesterol results in decreased expression of CDH5 mRNA; 27-hydroxycholesterol results in decreased expression of CDH5 protein |
CTD |
PMID:33131013 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdh6 |
cadherin 6 |
decreases expression |
ISO |
27-hydroxycholesterol results in decreased expression of CDH6 mRNA |
CTD |
PMID:33131013 |
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NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228
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G |
Ces1d |
carboxylesterase 1D |
decreases activity multiple interactions |
ISO |
27-hydroxycholesterol results in decreased activity of CES1 protein 27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin] |
CTD |
PMID:19761868 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases activity |
ISO |
27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]; 27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]; 27-hydroxycholesterol results in increased expression of and affects the localization of CTNNB1 protein; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein] 27-hydroxycholesterol results in increased activity of CTNNB1 protein |
CTD |
PMID:33131013 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of CXCL12 mRNA fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA] |
CTD |
PMID:17872378 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
increases abundance multiple interactions increases chemical synthesis |
ISO EXP |
CYP27A1 protein results in increased abundance of 27-hydroxycholesterol [CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol [[CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol] which results in increased activity of HMGCR protein; [CYP27A1 protein results in increased hydroxylation of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol; [CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol; [CYP27A1 protein results in increased oxidation of 27-hydroxycholesterol] which results in increased chemical synthesis of 3-hydroxy-5-cholestenoic acid; [TGFB1 protein results in increased expression of CYP27A1 protein] which results in increased abundance of 27-hydroxycholesterol CYP27A1 protein results in increased chemical synthesis of 27-hydroxycholesterol |
CTD |
PMID:8496670 PMID:9215552 PMID:9660774 PMID:11408283 PMID:11714861 PMID:12119285 PMID:12531903 PMID:14622972 PMID:15708352 More...
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases metabolic processing |
ISO EXP |
CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol |
CTD |
PMID:10882719 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
increases hydroxylation increases abundance increases metabolic processing |
ISO |
CYP7B1 protein results in increased hydroxylation of 27-hydroxycholesterol CYP7B1 gene mutant form results in increased abundance of 27-hydroxycholesterol CYP7B1 protein results in increased metabolism of 27-hydroxycholesterol |
CTD |
PMID:10588945 PMID:10748047 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
E2f1 |
E2F transcription factor 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of E2F1 mRNA |
CTD |
PMID:17872378 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
decreases expression |
ISO |
27-hydroxycholesterol results in decreased expression of ERBB4 mRNA |
CTD |
PMID:17872378 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases degradation affects response to substance |
ISO |
27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR1 protein; 27-hydroxycholesterol binds to and results in decreased activity of ESR1 protein; 27-hydroxycholesterol inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]; 27-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; 27-hydroxycholesterol promotes the reaction [ESR1 protein binds to TFF1 promoter]; fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased activity of ESR1 protein] 27-hydroxycholesterol results in increased degradation of ESR1 protein ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]; ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] ESR1 protein affects the susceptibility to 27-hydroxycholesterol |
CTD |
PMID:17872378 PMID:17873880 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects response to substance |
ISO |
27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR2 protein; 27-hydroxycholesterol binds to and results in decreased activity of ESR2 protein; 27-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein] ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]; ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] ESR2 protein affects the susceptibility to 27-hydroxycholesterol |
CTD |
PMID:17872378 PMID:17873880 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
decreases expression |
EXP |
27-hydroxycholesterol results in decreased expression of GRIN1 protein |
CTD |
PMID:18503570 |
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NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
decreases phosphorylation |
EXP |
27-hydroxycholesterol results in decreased phosphorylation of GRIN2A protein |
CTD |
PMID:18503570 |
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NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO |
27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]; 27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:33131013 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of HIF1A protein HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of HIF1A protein] |
CTD |
PMID:27856279 PMID:33880675 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases activity multiple interactions decreases expression |
ISO EXP |
27-hydroxycholesterol metabolite results in decreased activity of HMGCR protein; 27-hydroxycholesterol results in decreased activity of HMGCR protein [[CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol] which results in increased activity of HMGCR protein; Dehydroepiandrosterone inhibits the reaction [27-hydroxycholesterol results in decreased activity of HMGCR protein]; Pregnenolone inhibits the reaction [27-hydroxycholesterol results in decreased activity of HMGCR protein] 27-hydroxycholesterol results in decreased expression of HMGCR mRNA; 27-hydroxycholesterol results in decreased expression of HMGCR protein |
CTD |
PMID:7749852 PMID:7751816 PMID:7788503 PMID:9059514 PMID:11408283 PMID:18024962 PMID:28167099 More...
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of HMOX1 mRNA; 27-hydroxycholesterol results in increased expression of HMOX1 protein |
CTD |
PMID:33880675 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions increases expression |
ISO |
CAT protein inhibits the reaction [27-hydroxycholesterol results in increased expression of HSPA9 protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of HIF1A protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of MYC protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:33880675 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ICAM1 mRNA |
CTD |
PMID:19426978 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
27-hydroxycholesterol promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:11851725 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases secretion multiple interactions increases expression |
ISO |
27-hydroxycholesterol results in increased secretion of IL6 protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein]; IL6 protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein] |
CTD |
PMID:11851725 PMID:28739487 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Itgb1 |
integrin subunit beta 1 |
multiple interactions increases expression |
ISO |
[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of ITGB1 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of ITGB1 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of ITGB1 mRNA]; Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of ITGB1 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Lcat |
lecithin cholesterol acyltransferase |
increases metabolic processing |
ISO |
LCAT protein results in increased metabolism of 27-hydroxycholesterol |
CTD |
PMID:7744831 |
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NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Ldlr |
low density lipoprotein receptor |
decreases activity decreases expression |
ISO EXP |
27-hydroxycholesterol results in decreased activity of LDLR protein 27-hydroxycholesterol results in decreased expression of LDLR mRNA; 27-hydroxycholesterol results in decreased expression of LDLR protein |
CTD |
PMID:8820113 PMID:28167099 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lipe |
lipase E, hormone sensitive type |
multiple interactions |
ISO |
LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR mRNA]; LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR protein] |
CTD |
PMID:23362264 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
27-hydroxycholesterol results in increased phosphorylation of MAPK1 protein U 0126 inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:33131013 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
27-hydroxycholesterol results in increased phosphorylation of MAPK3 protein U 0126 inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:33131013 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of MMP9 mRNA Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of MMP9 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of MYC protein HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of MYC protein] |
CTD |
PMID:33880675 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO |
27-hydroxycholesterol inhibits the reaction [Estradiol results in increased expression of NOS2 mRNA]; ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]; ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA] |
CTD |
PMID:17873880 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression multiple interactions |
ISO |
27-hydroxycholesterol results in decreased expression of NOS3 mRNA 27-hydroxycholesterol inhibits the reaction [Estradiol results in increased expression of NOS3 mRNA]; ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA]; ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] |
CTD |
PMID:17873880 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Npc1 |
NPC intracellular cholesterol transporter 1 |
affects abundance |
ISO |
NPC1 protein affects the abundance of 27-hydroxycholesterol |
CTD |
PMID:18483620 |
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NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of NQO1 mRNA; 27-hydroxycholesterol results in increased expression of NQO1 protein |
CTD |
PMID:33880675 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
EXP |
27-hydroxycholesterol results in increased expression of NR1H3 mRNA; 27-hydroxycholesterol results in increased expression of NR1H3 protein |
CTD |
PMID:28167099 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
increases activity multiple interactions |
ISO |
27-hydroxycholesterol results in increased activity of NR5A1 protein 27-hydroxycholesterol promotes the reaction [NR5A1 protein results in increased expression of STAR protein] |
CTD |
PMID:9144161 PMID:9804848 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G |
Pgr |
progesterone receptor |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of PGR mRNA; 27-hydroxycholesterol results in increased expression of PGR protein fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of PGR mRNA] |
CTD |
PMID:17872378 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
EXP |
27-hydroxycholesterol results in increased expression of PPARG mRNA; 27-hydroxycholesterol results in increased expression of PPARG protein |
CTD |
PMID:28167099 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptges |
prostaglandin E synthase |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of PTGES mRNA Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of PTGES mRNA]; Quercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of PTGES mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of PTGS2 protein [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of PTGS2 protein |
CTD |
PMID:24802026 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Sele |
selectin E |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of SELE mRNA |
CTD |
PMID:19426978 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Smpd2 |
sphingomyelin phosphodiesterase 2 |
decreases activity |
ISO |
27-hydroxycholesterol results in decreased activity of SMPD2 protein |
CTD |
PMID:15261762 |
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NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441
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G |
Snca |
synuclein alpha |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of SNCA mRNA; 27-hydroxycholesterol results in increased expression of SNCA protein |
CTD |
PMID:18841091 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
decreases activity |
EXP |
27-hydroxycholesterol results in decreased activity of SRC protein |
CTD |
PMID:18503570 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
EXP |
27-hydroxycholesterol results in decreased expression of SREBF1 mRNA; 27-hydroxycholesterol results in decreased expression of SREBF1 protein |
CTD |
PMID:28167099 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions increases abundance increases expression |
ISO EXP |
27-hydroxycholesterol promotes the reaction [NR5A1 protein results in increased expression of STAR protein] STAR protein results in increased abundance of 27-hydroxycholesterol 27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR mRNA]; LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR protein] 27-hydroxycholesterol results in increased expression of STAR mRNA; 27-hydroxycholesterol results in increased expression of STAR protein |
CTD |
PMID:9804848 PMID:12368294 PMID:15863358 PMID:20083572 PMID:23362264 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein] Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; IL6 protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:27856279 PMID:28739487 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Tff1 |
trefoil factor 1 |
multiple interactions increases expression |
ISO |
27-hydroxycholesterol promotes the reaction [ESR1 protein binds to TFF1 promoter]; fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of TFF1 mRNA] |
CTD |
PMID:17872378 PMID:27856279 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
[TGFB1 protein results in increased expression of CYP27A1 protein] which results in increased abundance of 27-hydroxycholesterol |
CTD |
PMID:15708352 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tlr4 |
toll-like receptor 4 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of TLR4 mRNA [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]; Quercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]; Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of VCAM1 mRNA |
CTD |
PMID:19426978 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases secretion increases expression |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein] |
CTD |
PMID:27856279 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein] 27-hydroxycholesterol results in increased expression of VIM mRNA; 27-hydroxycholesterol results in increased expression of VIM protein |
CTD |
PMID:33131013 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Ywhah |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
multiple interactions |
ISO |
27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]; 27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; YWHAH protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:33131013 |
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NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance multiple interactions |
ISO |
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lipg |
lipase G, endothelial type |
increases hydrolysis |
ISO |
LIPG protein results in increased hydrolysis of 1-O-hexadecyl-2-arachidonyl-sn-glycero-3-phosphocholine |
CTD |
PMID:15953354 |
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NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lipc |
lipase C, hepatic type |
decreases abundance |
ISO |
LIPC gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance |
ISO |
LIPG gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
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NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Dagla |
diacylglycerol lipase, alpha |
increases metabolic processing |
ISO |
DAGLA protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol |
CTD |
PMID:18657971 |
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NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
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G |
Daglb |
diacylglycerol lipase, beta |
increases metabolic processing |
ISO |
DAGLB protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol |
CTD |
PMID:18657971 |
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NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
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G |
Dgke |
diacylglycerol kinase epsilon |
increases phosphorylation |
ISO |
DGKE protein results in increased phosphorylation of 1-stearoyl-2-arachidonoylglycerol |
CTD |
PMID:17455907 |
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NCBI chr10:73,853,030...73,877,334
Ensembl chr10:73,855,583...73,877,100
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
1-stearoyl-2-arachidonoylglycerol results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Trpm6 |
transient receptor potential cation channel, subfamily M, member 6 |
multiple interactions |
ISO |
TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium] |
CTD |
PMID:11988098 |
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NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
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G |
Ace |
angiotensin I converting enzyme |
decreases activity |
EXP |
14,15-epoxy-5,8,11-eicosatrienoic acid analog results in decreased activity of ACE protein |
CTD |
PMID:27428043 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin converting enzyme 2 |
multiple interactions |
ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid analog promotes the reaction [REN2 protein results in increased expression of ACE2 protein] |
CTD |
PMID:27428043 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Agt |
angiotensinogen |
decreases expression multiple interactions increases cleavage |
EXP ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid analog results in decreased expression of AGT protein modified form [14,15-epoxy-5,8,11-eicosatrienoic acid analog results in increased cleavage of AGT protein modified form] which results in increased abundance of angiotensin I (1-7) 14,15-epoxy-5,8,11-eicosatrienoic acid analog inhibits the reaction [REN2 protein results in increased expression of AGT protein modified form] |
CTD |
PMID:27428043 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation |
ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of AKT1 protein |
CTD |
PMID:16286479 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
increases chemical synthesis |
ISO |
CYP2C8 protein results in increased chemical synthesis of 14,15-epoxy-5,8,11-eicosatrienoic acid |
CTD |
PMID:12675279 |
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases chemical synthesis |
ISO |
Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 14,15-epoxy-5,8,11-eicosatrienoic acid] |
CTD |
PMID:12675279 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Ephx2 |
epoxide hydrolase 2 |
multiple interactions increases abundance |
ISO |
[Arsenites results in increased expression of and results in increased activity of EPHX2 protein] which results in decreased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid; [Mercuric Chloride results in increased expression of and results in increased activity of EPHX2 protein] which results in decreased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid EPHX2 gene mutant form results in increased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid |
CTD |
PMID:19896470 PMID:22680237 PMID:24472606 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Fgf2 |
fibroblast growth factor 2 |
increases expression |
ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid results in increased expression of FGF2 protein |
CTD |
PMID:16286479 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:19464254 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation |
ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:19464254 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
increases phosphorylation |
ISO |
14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of RPS6KB1 protein |
CTD |
PMID:16286479 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Tgfb1 |
transforming growth factor, beta 1 |
decreases secretion multiple interactions |
ISO |
TGFB1 protein results in decreased secretion of 14,15-epoxy-5,8,11-eicosatrienoic acid 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [TGFB1 protein results in decreased secretion of 14,15-epoxy-5,8,11-eicosatrienoic acid] |
CTD |
PMID:28694203 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
affects metabolic processing |
EXP |
CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:15205388 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases chemical synthesis |
ISO |
CYP4F3 protein alternative form results in increased chemical synthesis of 19-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:30259074 |
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NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
affects metabolic processing |
EXP |
CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:15205388 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases chemical synthesis |
ISO |
CYP4F3 protein alternative form results in increased chemical synthesis of 19-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:30259074 |
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NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
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G |
Abhd12 |
abhydrolase domain containing 12, lysophospholipase |
increases hydrolysis |
ISO |
ABHD12 protein results in increased hydrolysis of glyceryl 2-arachidonate |
CTD |
PMID:18096503 |
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NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564
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G |
Abhd6 |
abhydrolase domain containing 6, acylglycerol lipase |
increases hydrolysis |
ISO |
ABHD6 protein results in increased hydrolysis of glyceryl 2-arachidonate |
CTD |
PMID:18096503 |
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NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
EXP |
glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA] |
CTD |
PMID:21863215 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[[APOE protein affects the susceptibility to [Cholesterol, Dietary co-treated with Dietary Fats]] which affects the susceptibility to JZL 184] which affects the abundance of glyceryl 2-arachidonate |
CTD |
PMID:29813086 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Arrb1 |
arrestin, beta 1 |
multiple interactions |
ISO |
glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] |
CTD |
PMID:31024316 |
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NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
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G |
Arrb2 |
arrestin, beta 2 |
multiple interactions |
ISO |
[GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] |
CTD |
PMID:31024316 |
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NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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G |
Atf4 |
activating transcription factor 4 |
increases expression multiple interactions |
ISO |
glyceryl 2-arachidonate results in increased expression of ATF4 mRNA iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of ATF4 mRNA] |
CTD |
PMID:32357311 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of BTG2 mRNA |
CTD |
PMID:28095641 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of CCL2 protein |
CTD |
PMID:15115777 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccr1 |
C-C motif chemokine receptor 1 |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of CCR1 mRNA |
CTD |
PMID:29813086 |
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NCBI chr 8:123,556,286...123,561,841
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G |
Cd36 |
CD36 molecule |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of CD36 mRNA |
CTD |
PMID:29813086 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Ces1d |
carboxylesterase 1D |
increases hydrolysis multiple interactions |
ISO |
CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate [CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid |
CTD |
PMID:21049984 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Ces2h |
carboxylesterase 2H |
increases hydrolysis multiple interactions |
ISO |
CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate [CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid |
CTD |
PMID:21049984 |
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NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions increases expression |
ISO EXP |
[CNR1 protein affects the susceptibility to Chlorpyrifos] which affects the hydrolysis of glyceryl 2-arachidonate; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] glyceryl 2-arachidonate results in increased expression of CNR1 mRNA [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of CNR1 mRNA]; Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein] |
CTD |
PMID:12657697 PMID:15899896 PMID:16775503 PMID:21863215 PMID:23894352 PMID:26209559 PMID:28095641 PMID:31024316 PMID:36858108 More...
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions affects response to substance |
ISO |
[GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; glyceryl 2-arachidonate binds to and results in increased activity of CNR2 protein; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] CNR2 gene SNP affects the susceptibility to glyceryl 2-arachidonate |
CTD |
PMID:10617657 PMID:15115777 PMID:20124950 PMID:27194477 PMID:30102254 PMID:31024316 More...
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
multiple interactions increases expression |
ISO |
glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA] |
CTD |
PMID:23894352 |
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NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
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G |
Crh |
corticotropin releasing hormone |
increases abundance |
ISO |
CRH protein results in increased abundance of glyceryl 2-arachidonate |
CTD |
PMID:26821211 |
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NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA] |
CTD |
PMID:23894352 PMID:28095641 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions increases expression |
ISO |
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:23894352 PMID:28095641 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
increases expression multiple interactions |
ISO |
glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA] |
CTD |
PMID:23894352 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
increases expression multiple interactions |
ISO |
glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA] |
CTD |
PMID:23894352 PMID:28095641 |
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NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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G |
Dagla |
diacylglycerol lipase, alpha |
multiple interactions |
ISO |
1-((fluoro(methyl)phosphoryl)oxy)-3-isopropoxypropan-2-yl oleate inhibits the reaction [DAGLA protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate] |
CTD |
PMID:27071101 |
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NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
ISO |
glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA; glyceryl 2-arachidonate results in increased expression of DDIT3 protein iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 protein] |
CTD |
PMID:29441458 PMID:32357311 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases phosphorylation |
ISO |
GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:32357311 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Esrrg |
estrogen-related receptor gamma |
increases abundance |
ISO |
ESRRG protein results in increased abundance of glyceryl 2-arachidonate |
CTD |
PMID:31912162 |
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NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G |
Fabp1 |
fatty acid binding protein 1 |
affects abundance multiple interactions |
ISO |
FABP1 protein affects the abundance of glyceryl 2-arachidonate FABP1 protein affects the reaction [Dronabinol results in increased abundance of glyceryl 2-arachidonate]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide] |
CTD |
PMID:29414765 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fmr1 |
fragile X messenger ribonucleoprotein 1 |
multiple interactions |
ISO |
[FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate |
CTD |
PMID:20393458 |
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NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
EXP |
FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:12657697 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
Grk2 |
G protein-coupled receptor kinase 2 |
multiple interactions |
ISO |
[GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] |
CTD |
PMID:31024316 |
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NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
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G |
Hcrt |
hypocretin neuropeptide precursor |
increases chemical synthesis multiple interactions |
ISO |
HCRT protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate 1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea inhibits the reaction [HCRT protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate] |
CTD |
PMID:27071101 |
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NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of HSPA5 mRNA |
CTD |
PMID:32357311 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of ICAM1 mRNA |
CTD |
PMID:29813086 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il1b |
interleukin 1 beta |
decreases expression multiple interactions |
ISO |
glyceryl 2-arachidonate results in decreased expression of IL1B mRNA glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]] |
CTD |
PMID:16364651 PMID:30611738 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]] |
CTD |
PMID:21511917 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions |
ISO |
glyceryl 2-arachidonate results in decreased expression of IL6 mRNA glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]] |
CTD |
PMID:16364651 PMID:30611738 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]] |
CTD |
PMID:31408376 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:23894352 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Lep |
leptin |
multiple interactions |
ISO |
[Dietary Fats co-treated with LEP protein] results in increased chemical synthesis of glyceryl 2-arachidonate |
CTD |
PMID:27071101 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] |
CTD |
PMID:12657697 |
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NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] |
CTD |
PMID:12657697 |
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NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
ISO EXP |
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:12657697 PMID:31917333 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
ISO EXP |
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:12657697 PMID:31917333 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mgll |
monoglyceride lipase |
multiple interactions affects abundance increases degradation increases abundance increases hydrolysis |
EXP ISO |
[Chlorpyrifos results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; JZL 184 inhibits the reaction [MGLL protein results in increased hydrolysis of glyceryl 2-arachidonate] MGLL protein affects the abundance of glyceryl 2-arachidonate MGLL protein results in increased degradation of glyceryl 2-arachidonate [FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate; [JZL 184 results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; [MJN110 results in decreased activity of MGLL protein] which results in decreased hydrolysis of and results in increased abundance of glyceryl 2-arachidonate MGLL gene mutant form results in increased abundance of glyceryl 2-arachidonate |
CTD |
PMID:18096503 PMID:20393458 PMID:21507991 PMID:23761300 PMID:25030704 PMID:26209559 PMID:26642910 PMID:26791602 PMID:30301768 More...
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]] |
CTD |
PMID:30611738 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases cleavage |
ISO |
GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] |
CTD |
PMID:29441458 PMID:32357311 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects localization multiple interactions |
EXP |
glyceryl 2-arachidonate affects the localization of PPARA protein [palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]; glyceryl 2-arachidonate affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein] |
CTD |
PMID:31787870 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects binding multiple interactions increases expression |
ISO |
glyceryl 2-arachidonate metabolite binds to PPARG protein glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite results in increased expression of PPARG mRNA] |
CTD |
PMID:21511917 PMID:26209559 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
EXP |
[Indomethacin results in decreased expression of PTGS1] which results in increased activity of glyceryl 2-arachidonate |
CTD |
PMID:17245358 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases metabolic processing multiple interactions |
ISO |
PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]] glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate] |
CTD |
PMID:18297109 PMID:21511917 PMID:26209559 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] |
CTD |
PMID:26209559 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions |
ISO EXP |
glyceryl 2-arachidonate results in decreased expression of TNF mRNA glyceryl 2-arachidonate inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; glyceryl 2-arachidonate inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein] glyceryl 2-arachidonate inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein] |
CTD |
PMID:12509806 PMID:16364651 PMID:30611738 PMID:30769029 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions affects response to substance |
EXP ISO |
glyceryl 2-arachidonate binds to and results in increased activity of TRPV1 protein TRPV1 protein affects the susceptibility to glyceryl 2-arachidonate |
CTD |
PMID:18550765 PMID:21949157 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Yy1 |
YY1 transcription factor |
increases expression |
ISO |
glyceryl 2-arachidonate results in increased expression of YY1 mRNA |
CTD |
PMID:28095641 |
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NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
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G |
Fabp1 |
fatty acid binding protein 1 |
affects abundance |
ISO |
FABP1 protein affects the abundance of 2-oleoylglycerol |
CTD |
PMID:29414765 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Mgll |
monoglyceride lipase |
increases degradation multiple interactions |
EXP |
MGLL protein results in increased degradation of 2-oleoylglycerol Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol] |
CTD |
PMID:19515121 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
ISO |
20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 mRNA; 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 protein 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 mRNA]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 protein] |
CTD |
PMID:36368619 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Clock |
clock circadian regulator |
affects abundance |
ISO |
CLOCK protein affects the abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:22440902 |
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NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 mRNA]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 protein] 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 mRNA; 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 protein |
CTD |
PMID:36368619 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions increases chemical synthesis |
EXP |
20-hydroxy-5,8,11,14-eicosatetraenoic acid affects the reaction [CYP4A1 protein affects the susceptibility to Phenylephrine]; 20-hydroxy-5,8,11,14-eicosatetraenoic acid inhibits the reaction [DDMS inhibits the reaction [CYP4A1 protein results in increased susceptibility to Phenylephrine]] CYP4A1 protein results in increased chemical synthesis of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:11124159 PMID:12388396 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp4a2 |
cytochrome P450, family 4, subfamily a, polypeptide 2 |
increases expression |
EXP |
20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of CYP4A2 mRNA |
CTD |
PMID:22442195 |
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NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases chemical synthesis |
ISO |
CYP4F3 protein alternative form results in increased chemical synthesis of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:30259074 |
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NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
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G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
multiple interactions increases localization |
ISO EXP |
Cyclosporine inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein] |
CTD |
PMID:16055480 |
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NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
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G |
Pomc |
proopiomelanocortin |
multiple interactions increases abundance |
EXP |
HET0016 inhibits the reaction [POMC protein affects the abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid] POMC protein results in increased abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:18067589 PMID:19458537 |
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NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases phosphorylation |
ISO |
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased phosphorylation of SMAD3 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:36368619 |
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NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression |
ISO |
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 mRNA]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 protein] 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 mRNA; 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 protein |
CTD |
PMID:36368619 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases glucuronidation |
ISO |
UGT1A1 protein results in increased glucuronidation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:15231852 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a5 |
UDP glucuronosyltransferase family 1 member A5 |
increases glucuronidation |
ISO |
UGT1A4 protein results in increased glucuronidation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:15231852 |
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NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt2b7 |
UDP glucuronosyltransferase family 2 member B7 |
increases glucuronidation |
ISO |
UGT2B7 protein results in increased glucuronidation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid |
CTD |
PMID:15231852 |
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NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases expression multiple interactions |
ISO EXP |
27-hydroxycholesterol results in increased expression of ABCA1 mRNA; 27-hydroxycholesterol results in increased expression of ABCA1 protein Docosahexaenoic Acids inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA]; Linoleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA]; Oleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] [Fingolimod Hydrochloride results in increased abundance of 27-hydroxycholesterol] which results in increased expression of ABCA1 mRNA |
CTD |
PMID:15148325 PMID:17088262 PMID:18356535 PMID:18841091 PMID:20056921 PMID:28167099 More...
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ABCB1 mRNA |
CTD |
PMID:33880675 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ABCC1 mRNA |
CTD |
PMID:33880675 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ABCG1 protein |
CTD |
PMID:17088262 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein] |
CTD |
PMID:33131013 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of AKT1 protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:33131013 PMID:33880675 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
27-hydroxycholesterol promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; 27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]] |
CTD |
PMID:20083572 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoe |
apolipoprotein E |
increases expression |
EXP |
27-hydroxycholesterol results in increased expression of APOE mRNA; 27-hydroxycholesterol results in increased expression of APOE protein |
CTD |
PMID:28167099 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions increases expression decreases secretion |
ISO |
27-hydroxycholesterol results in decreased metabolism of and results in decreased secretion of APP protein 27-hydroxycholesterol results in increased expression of APP protein alternative form 27-hydroxycholesterol results in decreased secretion of APP protein alternative form |
CTD |
PMID:15148325 PMID:19126211 PMID:19158428 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arc |
activity-regulated cytoskeleton-associated protein |
decreases expression |
EXP |
27-hydroxycholesterol results in decreased expression of ARC protein |
CTD |
PMID:18503570 |
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NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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G |
Bace1 |
beta-secretase 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of BACE1 protein |
CTD |
PMID:19126211 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Cat |
catalase |
multiple interactions |
ISO |
CAT protein inhibits the reaction [27-hydroxycholesterol results in increased expression of HSPA9 protein] |
CTD |
PMID:33880675 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of CCL2 mRNA [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CCL2 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of CCL2 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CCL2 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression increases secretion |
ISO |
27-hydroxycholesterol results in increased expression of CCL3 mRNA 27-hydroxycholesterol results in increased secretion of CCL3 protein |
CTD |
PMID:24370436 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases secretion increases expression |
ISO |
27-hydroxycholesterol results in increased secretion of CCL4 protein 27-hydroxycholesterol results in increased expression of CCL4 mRNA |
CTD |
PMID:24370436 |
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccn5 |
cellular communication network factor 5 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of CCN5 mRNA Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CCN5 mRNA] |
CTD |
PMID:17872378 |
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NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO |
[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CD36 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of CD36 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CD36 mRNA]; Quercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of CD36 mRNA]; Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CD36 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdh5 |
cadherin 5 |
decreases expression multiple interactions |
ISO |
27-hydroxycholesterol results in decreased expression of CDH5 mRNA; 27-hydroxycholesterol results in decreased expression of CDH5 protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein] |
CTD |
PMID:33131013 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdh6 |
cadherin 6 |
decreases expression |
ISO |
27-hydroxycholesterol results in decreased expression of CDH6 mRNA |
CTD |
PMID:33131013 |
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NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228
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G |
Ces1d |
carboxylesterase 1D |
multiple interactions decreases activity |
ISO |
27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin] 27-hydroxycholesterol results in decreased activity of CES1 protein |
CTD |
PMID:19761868 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases activity |
ISO |
27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]; 27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]; 27-hydroxycholesterol results in increased expression of and affects the localization of CTNNB1 protein; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein] 27-hydroxycholesterol results in increased activity of CTNNB1 protein |
CTD |
PMID:33131013 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of CXCL12 mRNA fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA] |
CTD |
PMID:17872378 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
increases abundance increases chemical synthesis multiple interactions |
ISO EXP |
CYP27A1 protein results in increased abundance of 27-hydroxycholesterol CYP27A1 protein results in increased chemical synthesis of 27-hydroxycholesterol [CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol [[CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol] which results in increased activity of HMGCR protein; [CYP27A1 protein results in increased hydroxylation of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol; [CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol; [CYP27A1 protein results in increased oxidation of 27-hydroxycholesterol] which results in increased chemical synthesis of 3-hydroxy-5-cholestenoic acid; [TGFB1 protein results in increased expression of CYP27A1 protein] which results in increased abundance of 27-hydroxycholesterol |
CTD |
PMID:8496670 PMID:9215552 PMID:9660774 PMID:11408283 PMID:11714861 PMID:12119285 PMID:12531903 PMID:14622972 PMID:15708352 More...
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases metabolic processing |
ISO EXP |
CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol |
CTD |
PMID:10882719 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
increases abundance increases metabolic processing increases hydroxylation |
ISO |
CYP7B1 gene mutant form results in increased abundance of 27-hydroxycholesterol CYP7B1 protein results in increased metabolism of 27-hydroxycholesterol CYP7B1 protein results in increased hydroxylation of 27-hydroxycholesterol |
CTD |
PMID:10588945 PMID:10748047 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
E2f1 |
E2F transcription factor 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of E2F1 mRNA |
CTD |
PMID:17872378 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
decreases expression |
ISO |
27-hydroxycholesterol results in decreased expression of ERBB4 mRNA |
CTD |
PMID:17872378 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions affects response to substance increases degradation |
ISO |
27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR1 protein; 27-hydroxycholesterol binds to and results in decreased activity of ESR1 protein; 27-hydroxycholesterol inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]; 27-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; 27-hydroxycholesterol promotes the reaction [ESR1 protein binds to TFF1 promoter]; fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased activity of ESR1 protein] ESR1 protein affects the susceptibility to 27-hydroxycholesterol ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]; ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] 27-hydroxycholesterol results in increased degradation of ESR1 protein |
CTD |
PMID:17872378 PMID:17873880 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects response to substance |
ISO |
27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR2 protein; 27-hydroxycholesterol binds to and results in decreased activity of ESR2 protein; 27-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein] ESR2 protein affects the susceptibility to 27-hydroxycholesterol ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]; ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] |
CTD |
PMID:17872378 PMID:17873880 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
decreases expression |
EXP |
27-hydroxycholesterol results in decreased expression of GRIN1 protein |
CTD |
PMID:18503570 |
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NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
decreases phosphorylation |
EXP |
27-hydroxycholesterol results in decreased phosphorylation of GRIN2A protein |
CTD |
PMID:18503570 |
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NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation multiple interactions |
ISO |
27-hydroxycholesterol results in increased phosphorylation of GSK3B protein 27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]; 27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:33131013 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of HIF1A protein HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of HIF1A protein] |
CTD |
PMID:27856279 PMID:33880675 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions decreases expression decreases activity |
ISO EXP |
[[CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 27-hydroxycholesterol] which results in increased activity of HMGCR protein; Dehydroepiandrosterone inhibits the reaction [27-hydroxycholesterol results in decreased activity of HMGCR protein]; Pregnenolone inhibits the reaction [27-hydroxycholesterol results in decreased activity of HMGCR protein] 27-hydroxycholesterol results in decreased expression of HMGCR mRNA; 27-hydroxycholesterol results in decreased expression of HMGCR protein 27-hydroxycholesterol metabolite results in decreased activity of HMGCR protein; 27-hydroxycholesterol results in decreased activity of HMGCR protein |
CTD |
PMID:7749852 PMID:7751816 PMID:7788503 PMID:9059514 PMID:11408283 PMID:18024962 PMID:28167099 More...
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of HMOX1 mRNA; 27-hydroxycholesterol results in increased expression of HMOX1 protein |
CTD |
PMID:33880675 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions increases expression |
ISO |
CAT protein inhibits the reaction [27-hydroxycholesterol results in increased expression of HSPA9 protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of HIF1A protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of MYC protein]; HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:33880675 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of ICAM1 mRNA |
CTD |
PMID:19426978 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
27-hydroxycholesterol promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:11851725 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases secretion multiple interactions increases expression |
ISO |
27-hydroxycholesterol results in increased secretion of IL6 protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein]; IL6 protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein] |
CTD |
PMID:11851725 PMID:28739487 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Itgb1 |
integrin subunit beta 1 |
multiple interactions increases expression |
ISO |
[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of ITGB1 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of ITGB1 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of ITGB1 mRNA]; Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of ITGB1 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Lcat |
lecithin cholesterol acyltransferase |
increases metabolic processing |
ISO |
LCAT protein results in increased metabolism of 27-hydroxycholesterol |
CTD |
PMID:7744831 |
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NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Ldlr |
low density lipoprotein receptor |
decreases activity decreases expression |
ISO EXP |
27-hydroxycholesterol results in decreased activity of LDLR protein 27-hydroxycholesterol results in decreased expression of LDLR mRNA; 27-hydroxycholesterol results in decreased expression of LDLR protein |
CTD |
PMID:8820113 PMID:28167099 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lipe |
lipase E, hormone sensitive type |
multiple interactions |
ISO |
LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR mRNA]; LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR protein] |
CTD |
PMID:23362264 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
U 0126 inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:33131013 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
27-hydroxycholesterol results in increased phosphorylation of MAPK3 protein U 0126 inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:33131013 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO |
Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of MMP9 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of MYC protein HSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of MYC protein] |
CTD |
PMID:33880675 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO |
27-hydroxycholesterol inhibits the reaction [Estradiol results in increased expression of NOS2 mRNA]; ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]; ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA] |
CTD |
PMID:17873880 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions decreases expression |
ISO |
27-hydroxycholesterol inhibits the reaction [Estradiol results in increased expression of NOS3 mRNA]; ESR1 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA]; ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA] |
CTD |
PMID:17873880 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Npc1 |
NPC intracellular cholesterol transporter 1 |
affects abundance |
ISO |
NPC1 protein affects the abundance of 27-hydroxycholesterol |
CTD |
PMID:18483620 |
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NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of NQO1 mRNA; 27-hydroxycholesterol results in increased expression of NQO1 protein |
CTD |
PMID:33880675 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
EXP |
27-hydroxycholesterol results in increased expression of NR1H3 mRNA; 27-hydroxycholesterol results in increased expression of NR1H3 protein |
CTD |
PMID:28167099 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
increases activity multiple interactions |
ISO |
27-hydroxycholesterol results in increased activity of NR5A1 protein 27-hydroxycholesterol promotes the reaction [NR5A1 protein results in increased expression of STAR protein] |
CTD |
PMID:9144161 PMID:9804848 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G |
Pgr |
progesterone receptor |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of PGR mRNA; 27-hydroxycholesterol results in increased expression of PGR protein fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of PGR mRNA] |
CTD |
PMID:17872378 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
EXP |
27-hydroxycholesterol results in increased expression of PPARG mRNA; 27-hydroxycholesterol results in increased expression of PPARG protein |
CTD |
PMID:28167099 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptges |
prostaglandin E synthase |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of PTGES mRNA Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of PTGES mRNA]; Quercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of PTGES mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of PTGS2 protein [24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of PTGS2 protein |
CTD |
PMID:24802026 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Sele |
selectin E |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of SELE mRNA |
CTD |
PMID:19426978 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Smpd2 |
sphingomyelin phosphodiesterase 2 |
decreases activity |
ISO |
27-hydroxycholesterol results in decreased activity of SMPD2 protein |
CTD |
PMID:15261762 |
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NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441
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G |
Snca |
synuclein alpha |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of SNCA mRNA; 27-hydroxycholesterol results in increased expression of SNCA protein |
CTD |
PMID:18841091 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
decreases activity |
EXP |
27-hydroxycholesterol results in decreased activity of SRC protein |
CTD |
PMID:18503570 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
EXP |
27-hydroxycholesterol results in decreased expression of SREBF1 mRNA; 27-hydroxycholesterol results in decreased expression of SREBF1 protein |
CTD |
PMID:28167099 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions increases expression increases abundance |
ISO EXP |
27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR mRNA]; LIPE protein promotes the reaction [27-hydroxycholesterol results in increased expression of STAR protein] 27-hydroxycholesterol results in increased expression of STAR mRNA; 27-hydroxycholesterol results in increased expression of STAR protein STAR protein results in increased abundance of 27-hydroxycholesterol 27-hydroxycholesterol promotes the reaction [NR5A1 protein results in increased expression of STAR protein] |
CTD |
PMID:9804848 PMID:12368294 PMID:15863358 PMID:20083572 PMID:23362264 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stat3 |
signal transducer and activator of transcription 3 |
increases phosphorylation multiple interactions |
ISO |
27-hydroxycholesterol results in increased phosphorylation of STAT3 protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; IL6 protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein] Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein] |
CTD |
PMID:27856279 PMID:28739487 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Tff1 |
trefoil factor 1 |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of TFF1 mRNA 27-hydroxycholesterol promotes the reaction [ESR1 protein binds to TFF1 promoter]; fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of TFF1 mRNA] |
CTD |
PMID:17872378 PMID:27856279 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
[TGFB1 protein results in increased expression of CYP27A1 protein] which results in increased abundance of 27-hydroxycholesterol |
CTD |
PMID:15708352 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression |
ISO |
[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA]; Quercetin inhibits the reaction [27-hydroxycholesterol results in increased expression of TLR4 mRNA]; Quercetin inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of TLR4 mRNA] |
CTD |
PMID:24802026 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
increases expression |
ISO |
27-hydroxycholesterol results in increased expression of VCAM1 mRNA |
CTD |
PMID:19426978 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vegfa |
vascular endothelial growth factor A |
increases secretion multiple interactions increases expression |
ISO |
27-hydroxycholesterol results in increased secretion of VEGFA protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; STAT3 protein promotes the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein] |
CTD |
PMID:27856279 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
increases expression multiple interactions |
ISO |
27-hydroxycholesterol results in increased expression of VIM mRNA; 27-hydroxycholesterol results in increased expression of VIM protein Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; CTNNB1 protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; SCIO-469 inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein] |
CTD |
PMID:33131013 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Ywhah |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
multiple interactions |
ISO |
27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]; 27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; SCIO-469 inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; YWHAH protein affects the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; YWHAH protein affects the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:33131013 |
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NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases chemical synthesis |
ISO |
Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 5,6-epoxy-8,11,14-eicosatrienoic acid] |
CTD |
PMID:12675279 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Ephx2 |
epoxide hydrolase 2 |
increases abundance |
ISO |
EPHX2 gene mutant form results in increased abundance of 5,6-epoxy-8,11,14-eicosatrienoic acid |
CTD |
PMID:19896470 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases chemical synthesis |
ISO |
Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 8,9-epoxyeicosatrienoic acid] |
CTD |
PMID:12675279 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Ephx1 |
epoxide hydrolase 1 |
affects hydrolysis |
ISO |
EPHX1 protein affects the hydrolysis of 8,9-epoxyeicosatrienoic acid |
CTD |
PMID:28975360 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Ephx2 |
epoxide hydrolase 2 |
increases abundance |
ISO |
EPHX2 gene mutant form results in increased abundance of 8,9-epoxyeicosatrienoic acid |
CTD |
PMID:19896470 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
arachidonyltrifluoromethane inhibits the reaction [AGT protein results in increased abundance of Epoprostenol] |
CTD |
PMID:14613874 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:18938131 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] |
CTD |
PMID:19014389 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [NAD inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased secretion of IL1B protein]] |
CTD |
PMID:29642561 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
arachidonyltrifluoromethane inhibits the reaction [BL 11282 promotes the reaction [Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:17922229 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
increases secretion multiple interactions |
ISO |
arachidonyltrifluoromethane results in increased secretion of INS protein arachidonyltrifluoromethane inhibits the reaction [Glucose results in increased secretion of INS protein] |
CTD |
PMID:17192482 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Lep |
leptin |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of LEP mRNA] |
CTD |
PMID:19063610 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:15231676 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:15231676 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK1 protein]; arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:15231676 |
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NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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G |
Pla2g4a |
phospholipase A2 group IVA |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of PLA2G4A protein] arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA] |
CTD |
PMID:18938131 PMID:19063610 PMID:19162293 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG mRNA] |
CTD |
PMID:19063610 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of PTGS2 protein]; arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]] |
CTD |
PMID:18938131 PMID:19063610 PMID:19162293 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
S100a11 |
S100 calcium binding protein A11 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [S100A11 mutant form results in increased susceptibility to Cisplatin]; arachidonyltrifluoromethane inhibits the reaction [S100A11 mutant form results in increased susceptibility to Oxaliplatin] |
CTD |
PMID:25940438 |
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NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS3 mRNA] |
CTD |
PMID:19063610 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [TNF protein results in increased expression of SOD2] |
CTD |
PMID:11264281 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [TNF protein results in increased expression of SOD2] |
CTD |
PMID:11264281 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]] |
CTD |
PMID:19063610 PMID:19162293 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases export |
ISO |
ABCB1 protein results in increased export of anandamide |
CTD |
PMID:30102254 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions decreases expression |
ISO |
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]; anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of ABCG2 mRNA]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; iodopravadoline inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA] anandamide results in decreased expression of ABCG2 mRNA; anandamide results in decreased expression of ABCG2 protein |
CTD |
PMID:30610963 PMID:34756920 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Acox1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of ACOX1 mRNA] |
CTD |
PMID:34756920 |
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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G |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
multiple interactions |
ISO |
anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of AGPAT2 mRNA] |
CTD |
PMID:34756920 |
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NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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G |
App |
amyloid beta precursor protein |
decreases response to substance decreases metabolic processing decreases abundance |
EXP ISO |
anandamide results in decreased susceptibility to APP protein APP protein results in decreased metabolism of anandamide APP protein results in decreased abundance of anandamide |
CTD |
PMID:22233683 PMID:26976670 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arrb2 |
arrestin, beta 2 |
multiple interactions |
ISO |
anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein] |
CTD |
PMID:31024316 |
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NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions decreases activity |
ISO |
AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] |
CTD |
PMID:19022239 |
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NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
anandamide results in increased cleavage of CASP3 protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased cleavage of CASP3 protein] |
CTD |
PMID:26513129 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cd36 |
CD36 molecule |
increases expression |
ISO |
anandamide results in increased expression of CD36 mRNA; anandamide results in increased expression of CD36 protein |
CTD |
PMID:17360047 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
decreases expression |
ISO |
anandamide results in decreased expression of CGA mRNA |
CTD |
PMID:30610963 |
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NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Cnr1 |
cannabinoid receptor 1 |
affects activity increases response to substance decreases expression affects binding increases activity multiple interactions |
ISO EXP |
anandamide affects the activity of CNR1 protein CNR1 protein results in increased susceptibility to anandamide anandamide results in decreased expression of CNR1 protein anandamide binds to CNR1 protein anandamide results in increased activity of CNR1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased activity of CNR1]; anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Pertussis Toxin inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1] [anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]; [CNR1 protein affects the susceptibility to Chlorpyrifos] which affects the hydrolysis of anandamide; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; SR 144528 inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]] |
CTD |
PMID:10871313 PMID:11408034 PMID:11891798 PMID:12657697 PMID:14504685 PMID:15453094 PMID:17557913 PMID:19147270 PMID:29730318 PMID:31024316 PMID:31199905 PMID:36858108 More...
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
affects activity affects binding multiple interactions |
ISO EXP |
anandamide affects the activity of CNR2 protein anandamide binds to CNR2 protein anandamide binds to and results in increased activity of CNR2 protein; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide] |
CTD |
PMID:10617657 PMID:10688601 PMID:15453094 PMID:19147270 PMID:30102254 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions decreases phosphorylation |
ISO |
anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]] anandamide results in decreased phosphorylation of CREB1 protein |
CTD |
PMID:30610963 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crh |
corticotropin releasing hormone |
decreases abundance |
ISO |
CRH protein results in decreased abundance of anandamide |
CTD |
PMID:26821211 |
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NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
multiple interactions increases metabolic processing |
ISO |
cannabichromene inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; Cannabidiol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; cannabigerol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; Cannabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; delta-8-tetrahydrocannabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; Dronabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide] |
CTD |
PMID:29689453 |
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NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
ISO |
anandamide results in increased expression of DDIT3 mRNA; anandamide results in increased expression of DDIT3 protein 4-phenylbutyric acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein] |
CTD |
PMID:21949157 PMID:26513129 PMID:29441458 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO |
anandamide results in increased phosphorylation of EIF2S1 protein 4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:26513129 |
|
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Ervfrd-1 |
endogenous retrovirus group FRD member 1, envelope |
decreases expression |
ISO |
anandamide results in decreased expression of ERVFRD-1 mRNA |
CTD |
PMID:30610963 |
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NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions increases expression |
ISO |
anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein] anandamide results in increased expression of F3 protein |
CTD |
PMID:27556861 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Faah |
fatty acid amide hydrolase |
increases degradation increases response to substance decreases metabolic processing multiple interactions affects expression |
ISO EXP |
FAAH results in increased degradation of anandamide FAAH gene mutant form results in increased susceptibility to anandamide FAAH gene mutant form results in decreased metabolism of anandamide FAAH protein results in increased degradation of anandamide [Chlorpyrifos results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [Lipopolysaccharides results in decreased expression of FAAH protein] which results in increased abundance of anandamide; FAAH protein results in increased metabolism of and results in decreased activity of anandamide; Nitroglycerin promotes the reaction [FAAH protein results in increased degradation of anandamide]; Silybin inhibits the reaction [FAAH protein results in increased metabolism of and results in decreased activity of anandamide] anandamide affects the expression of FAAH protein [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]; [PF 3845 results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide] |
CTD |
PMID:11556820 PMID:16131814 PMID:16886060 PMID:19515121 PMID:20702753 PMID:23761300 PMID:26642910 PMID:27307500 PMID:27385208 PMID:29787777 PMID:31121907 PMID:37245739 More...
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NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions affects abundance affects binding |
EXP ISO |
11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [anandamide analog binds to FABP1 protein]; Dronabinol inhibits the reaction [anandamide analog binds to FABP1 protein] FABP1 protein affects the abundance of anandamide FABP1 protein affects the reaction [Dronabinol results in increased abundance of anandamide]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide] |
CTD |
PMID:29414765 PMID:30232874 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP |
anandamide inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; capsazepine inhibits the reaction [anandamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [anandamide results in increased expression of FOS protein] anandamide results in increased expression of FOS; anandamide results in increased expression of FOS protein |
CTD |
PMID:9748483 PMID:15601931 PMID:19515121 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]; anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B] |
CTD |
PMID:12813001 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf1 |
insulin-like growth factor 1 |
increases expression |
ISO |
anandamide results in increased expression of IGF1 protein |
CTD |
PMID:17307377 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
[OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]; anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15748152 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]] anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B]; anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein] |
CTD |
PMID:12813001 PMID:15748152 PMID:27556861 PMID:30611738 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]] |
CTD |
PMID:30611738 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Lep |
leptin |
decreases abundance multiple interactions decreases activity decreases transport |
ISO |
LEP protein results in decreased abundance of anandamide Dietary Fats inhibits the reaction [LEP protein results in decreased abundance of anandamide] LEP protein results in decreased activity of anandamide LEP protein results in decreased transport of anandamide |
CTD |
PMID:16154199 PMID:29967158 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein] |
CTD |
PMID:12657697 |
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NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] |
CTD |
PMID:12657697 |
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NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein] anandamide results in increased phosphorylation of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK1 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein] 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:12657697 PMID:19477951 PMID:21179406 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein] anandamide results in increased phosphorylation of MAPK3 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK3 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein] 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:12657697 PMID:19477951 PMID:21179406 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
anandamide results in increased expression of MMP1 mRNA |
CTD |
PMID:16330497 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp3 |
matrix metallopeptidase 3 |
increases expression |
ISO |
anandamide results in increased expression of MMP3 mRNA |
CTD |
PMID:16330497 |
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO |
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of MMP9 mRNA] |
CTD |
PMID:16330497 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:11891798 PMID:15748152 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
anandamide results in increased cleavage of PARP1 protein |
CTD |
PMID:29441458 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
anandamide binds to and results in increased activity of PPARA protein |
CTD |
PMID:17906680 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases metabolic processing |
EXP ISO |
[nimesulide results in decreased expression of PTGS2] which results in increased activity of anandamide anandamide results in increased expression of PTGS2 mRNA; anandamide results in increased expression of PTGS2 protein PTGS2 results in increased metabolism of anandamide [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide] |
CTD |
PMID:16330497 PMID:17245358 PMID:20702753 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Selp |
selectin P |
multiple interactions increases expression |
ISO |
anandamide inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased expression of SELP protein] anandamide results in increased expression of SELP protein |
CTD |
PMID:27151562 |
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NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression multiple interactions |
ISO |
anandamide results in increased expression of TIMP1 mRNA N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA] |
CTD |
PMID:16330497 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases abundance |
EXP ISO |
anandamide inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein] anandamide inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein] TNF protein results in increased abundance of anandamide anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF] |
CTD |
PMID:12509806 PMID:12813001 PMID:20626112 PMID:30611738 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases response to substance increases activity affects response to substance affects binding |
ISO EXP |
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Egtazic Acid inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; methyl arachidonylfluorophosphonate promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; N-(2-methyl-3-hydroxyphenyl)-5,8,11,14-eicosatetraenamide inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Nitroprusside promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Phenylmethylsulfonyl Fluoride promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein] TRPV1 protein results in increased susceptibility to anandamide anandamide results in increased activity of TRPV1 protein 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; bisindolylmaleimide inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein] anandamide binds to TRPV1 protein |
CTD |
PMID:11140687 PMID:11278420 PMID:14504685 PMID:15453094 PMID:15601931 PMID:15615864 PMID:17038422 PMID:17913835 PMID:18550765 PMID:21949157 More...
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
anandamide results in decreased expression of and results in decreased secretion of VEGFA protein |
CTD |
PMID:15313899 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases degradation |
ISO |
Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] Arachidonic Acid results in increased degradation of ABCA1 protein |
CTD |
PMID:16118212 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA] |
CTD |
PMID:15307955 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ABCD3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ABCG1 mRNA |
CTD |
PMID:16730733 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Adarb1 |
adenosine deaminase, RNA-specific, B1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ADARB1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
Eicosapentaenoic Acid inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid]; Quinacrine inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid] |
CTD |
PMID:16257180 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
AHR affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [PLA2G4A protein results in increased secretion of Arachidonic Acid]] |
CTD |
PMID:19162293 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Arachidonic Acid results in increased phosphorylation of AKT1 protein aristolochic acid I inhibits the reaction [Arachidonic Acid results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:19344371 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alox12 |
arachidonate 12-lipoxygenase, 12S type |
affects response to substance increases metabolic processing |
ISO |
ALOX12 protein affects the susceptibility to Arachidonic Acid ALOX12 protein results in increased metabolism of Arachidonic Acid |
CTD |
PMID:17027136 PMID:19373248 |
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NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
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G |
Alox12b |
arachidonate 12-lipoxygenase, 12R type |
multiple interactions |
ISO |
[TP53 protein results in increased expression of ALOX12B mRNA] which results in increased metabolism of Arachidonic Acid |
CTD |
PMID:30258081 |
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NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
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G |
Alox15 |
arachidonate 15-lipoxygenase |
affects metabolic processing multiple interactions increases metabolic processing |
ISO |
ALOX15 protein affects the metabolism of Arachidonic Acid [ALOX15 protein affects the metabolism of Arachidonic Acid] which affects the susceptibility to Acetylcholine; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 11,12,15-trihydroxyeicosatrienoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 11,14,15-trihydroxyeicosa-5,8,12-trienoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 15-hydroxy-11,12-epoxyeicosatrienoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 15-hydroxy-5,8,11,13-eicosatetraenoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 6-Ketoprostaglandin F1 alpha; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of Dinoprostone; ALOX15 protein results in increased metabolism of and affects the susceptibility to Arachidonic Acid ALOX15 protein results in increased metabolism of Arachidonic Acid [IL4 protein co-treated with Arachidonic Acid] results in increased activity of ALOX15 protein; [IL4 protein co-treated with Arachidonic Acid] results in increased expression of ALOX15 mRNA |
CTD |
PMID:8305483 PMID:11861792 PMID:21193584 PMID:23872364 |
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NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions increases metabolic processing |
ISO |
[sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein; [Sorbitol co-treated with Calcimycin co-treated with Arachidonic Acid] affects the localization of ALOX5 protein; [TP53 protein results in increased expression of ALOX5 mRNA] which results in increased metabolism of Arachidonic Acid; [zileuton results in decreased activity of ALOX5 protein] which affects the abundance of Arachidonic Acid; [zileuton results in decreased activity of ALOX5 protein] which results in decreased susceptibility to Arachidonic Acid; Arachidonic Acid inhibits the reaction [L 708714 binds to ALOX5 protein]; CJ 13610 inhibits the reaction [ALOX5 protein results in increased metabolism of Arachidonic Acid]; zileuton inhibits the reaction [ALOX5 protein results in increased metabolism of Arachidonic Acid] |
CTD |
PMID:7577949 PMID:7592874 PMID:9495842 PMID:10779545 PMID:11698504 PMID:18295198 PMID:30258081 More...
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions decreases expression |
ISO |
Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] Arachidonic Acid results in decreased expression of APOA1 mRNA |
CTD |
PMID:7983038 PMID:16118212 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoc1 |
apolipoprotein C1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of APOC1 mRNA |
CTD |
PMID:16623957 |
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NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
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G |
Apoe |
apolipoprotein E |
multiple interactions decreases response to substance |
ISO |
APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]; Aspirin inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; dazoxiben inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; tempol inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] Aspirin inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]; dazoxiben inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]; Indomethacin promotes the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]; tempol inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid] |
CTD |
PMID:20530721 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
increases secretion multiple interactions |
ISO |
APP protein modified form results in increased secretion of Arachidonic Acid [1,1,1,2,2-pentafluoro-7-phenylheptan-3-one co-treated with Orlistat] inhibits the reaction [APP protein modified form results in increased secretion of Arachidonic Acid] |
CTD |
PMID:28721267 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of AQP3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
increases expression |
ISO |
Arachidonic Acid results in increased expression of ARHGDIA mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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G |
Atf1 |
activating transcription factor 1 |
multiple interactions |
ISO |
Arachidonic Acid inhibits the reaction [Quercetin results in increased phosphorylation of ATF1 protein] |
CTD |
PMID:20551291 |
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NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions increases phosphorylation |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased phosphorylation of ATF2 protein] |
CTD |
PMID:19720122 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of ATF3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Avp |
arginine vasopressin |
increases abundance |
EXP |
AVP protein results in increased abundance of Arachidonic Acid |
CTD |
PMID:11356622 |
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NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
[Arachidonic Acid co-treated with Iron] results in increased expression of BAD protein; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of BAD protein] |
CTD |
PMID:30626086 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Barx1 |
BARX homeobox 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of BARX1 mRNA |
CTD |
PMID:16623957 |
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NCBI chr17:15,990,412...15,993,887
Ensembl chr17:15,990,412...15,993,887
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions affects localization |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; [Arachidonic Acid co-treated with Iron] results in increased expression of BAX protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [Arachidonic Acid affects the localization of BAX protein] |
CTD |
PMID:19540902 PMID:19720122 PMID:30626086 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO |
Arachidonic Acid results in decreased expression of BCL2 protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; [Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2 protein] |
CTD |
PMID:19540902 PMID:19620254 PMID:19720122 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions decreases expression |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; [Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]; pyrazolanthrone inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein] |
CTD |
PMID:19540902 PMID:19620254 PMID:19720122 PMID:27916511 PMID:30626086 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of BDNF mRNA |
CTD |
PMID:16704987 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bid |
BH3 interacting domain death agonist |
increases cleavage multiple interactions |
ISO |
Arachidonic Acid results in increased cleavage of BID protein FADD protein promotes the reaction [Arachidonic Acid results in increased cleavage of BID protein] |
CTD |
PMID:19720122 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Casp3 |
caspase 3 |
increases activity multiple interactions increases degradation |
ISO |
Arachidonic Acid results in increased activity of CASP3 protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased degradation of CASP3 protein alternative form]; [Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein] |
CTD |
PMID:16704987 PMID:19540902 PMID:19620254 PMID:19720122 PMID:23266427 PMID:27916511 PMID:30626086 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions increases activity |
ISO |
FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP8 protein] |
CTD |
PMID:19720122 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity |
ISO |
Arachidonic Acid results in increased activity of CASP9 protein |
CTD |
PMID:19540902 PMID:19720122 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat |
catalase |
increases activity |
EXP |
Arachidonic Acid results in increased activity of CAT protein |
CTD |
PMID:7548195 PMID:16982041 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] |
CTD |
PMID:15684433 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Ces1d |
carboxylesterase 1D |
decreases activity multiple interactions |
ISO EXP |
Arachidonic Acid results in decreased activity of CES1 protein [Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein; epigallocatechin gallate inhibits the reaction [[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein]; gallocatechol inhibits the reaction [[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein] [Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein; [CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid; epigallocatechin gallate inhibits the reaction [[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein] |
CTD |
PMID:19761868 PMID:21049984 PMID:37353134 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Ces2h |
carboxylesterase 2H |
multiple interactions |
ISO |
[CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid |
CTD |
PMID:21049984 |
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NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
CNR2 protein affects the reaction [Arachidonic Acid results in increased expression of CXCL8 protein] |
CTD |
PMID:15115777 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Col18a1 |
collagen type XVIII alpha 1 chain |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of COL18A1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
ISO |
Arachidonic Acid results in increased expression of CPT1A mRNA |
CTD |
PMID:15307955 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases phosphorylation multiple interactions |
EXP |
Arachidonic Acid results in increased phosphorylation of CREB1 protein Ketoconazole inhibits the reaction [Arachidonic Acid results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:17680988 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Csk |
C-terminal Src kinase |
increases activity affects localization |
ISO |
Arachidonic Acid results in increased activity of CSK protein Arachidonic Acid affects the localization of CSK protein |
CTD |
PMID:18388244 |
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NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
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G |
Ctdspl |
CTD small phosphatase like |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of CTDSPL mRNA |
CTD |
PMID:16704987 |
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NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:118,642,672...118,767,117
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G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
Arachidonic Acid affects the localization of CYCS protein |
CTD |
PMID:19720122 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cygb |
cytoglobin |
multiple interactions |
EXP |
CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA]; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA]; CYGB protein results in decreased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid] |
CTD |
PMID:16581302 |
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NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
affects metabolic processing multiple interactions |
ISO |
CYP1A1 protein affects the metabolism of Arachidonic Acid Arachidonic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:15258110 PMID:19063610 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases metabolic processing decreases activity |
ISO |
CYP1A2 protein results in increased metabolism of Arachidonic Acid Arachidonic Acid results in decreased activity of CYP1A2 protein |
CTD |
PMID:12675279 PMID:16978661 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
affects metabolic processing |
ISO |
CYP1B1 protein affects the metabolism of Arachidonic Acid |
CTD |
PMID:15258110 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of CYP24A1 mRNA |
CTD |
PMID:16623957 |
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NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases metabolic processing |
ISO |
CYP2B6 protein results in increased metabolism of Arachidonic Acid |
CTD |
PMID:12675279 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
decreases activity increases metabolic processing multiple interactions |
ISO |
Arachidonic Acid results in decreased activity of CYP2C19 protein CYP2C19 protein results in increased metabolism of Arachidonic Acid CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid]; CYP2C19 protein results in increased metabolism of [Arachidonic Acid co-treated with NADP] |
CTD |
PMID:12675279 PMID:16978661 PMID:18004210 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
increases metabolic processing |
ISO |
CYP2C8 protein results in increased metabolism of Arachidonic Acid |
CTD |
PMID:12675279 |
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G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
increases metabolic processing |
ISO |
CYP2D6 protein results in increased metabolism of Arachidonic Acid |
CTD |
PMID:12675279 |
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NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions affects hydroxylation increases response to substance decreases activity |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein; [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein; [Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein; [CYP2E1 protein co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Hydrogen Peroxide co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; allyl sulfide inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; allyl sulfide inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; Arachidonic Acid inhibits the reaction [CYP2E1 protein results in decreased expression of KLF6 mRNA alternative form]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]; Cadmium Chloride affects the reaction [CYP2E1 protein results in increased susceptibility to Arachidonic Acid]; CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]; CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]; CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; pyrazolanthrone inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; SB 203580 promotes the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Wortmannin inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Arachidonic Acid] CYP2E1 protein affects the hydroxylation of Arachidonic Acid Arachidonic Acid results in decreased activity of CYP2E1 protein |
CTD |
PMID:12086689 PMID:12566070 PMID:15205388 PMID:16978661 PMID:17034788 PMID:21352821 PMID:22486562 More...
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
multiple interactions |
ISO |
Arachidonic Acid inhibits the reaction [CYP2J2 protein results in decreased methylation of Astemizole] |
CTD |
PMID:12386130 |
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NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases metabolic processing decreases activity |
ISO |
Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Arachidonic Acid] Arachidonic Acid results in decreased activity of CYP3A4 protein |
CTD |
PMID:12675279 PMID:16978661 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
multiple interactions increases hydroxylation |
ISO |
rubiarbonone C inhibits the reaction [CYP4F3 protein alternative form results in increased hydroxylation of Arachidonic Acid] |
CTD |
PMID:30259074 |
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NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
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G |
Dct |
dopachrome tautomerase |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of DCT mRNA |
CTD |
PMID:16623957 |
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NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of DDIT4 mRNA |
CTD |
PMID:16704987 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddx24 |
DEAD-box helicase 24 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of DDX24 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927
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G |
Des |
desmin |
increases expression |
EXP |
Arachidonic Acid results in increased expression of DES mRNA |
CTD |
PMID:19089455 |
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NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of DHCR7 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Ebp |
EBP, cholestenol delta-isomerase |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of EBP mRNA |
CTD |
PMID:16704987 |
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NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
EXP |
5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Arachidonic Acid results in increased phosphorylation of and results in increased activity of EGFR protein] |
CTD |
PMID:15525798 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of EGR1 mRNA |
CTD |
PMID:8764118 PMID:16704987 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Eif4ebp3 |
eukaryotic translation initiation factor 4E binding protein 3 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of EIF4EBP3 protein] |
CTD |
PMID:20551291 |
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NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024
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G |
Ephx2 |
epoxide hydrolase 2 |
increases metabolic processing |
ISO |
EPHX2 protein results in increased metabolism of Arachidonic Acid |
CTD |
PMID:26165641 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Erg28 |
ergosterol biosynthesis 28 homolog |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ERG28 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078
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G |
F3 |
coagulation factor III, tissue factor |
increases expression |
ISO |
Arachidonic Acid results in increased expression of F3 protein |
CTD |
PMID:27556861 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Faah |
fatty acid amide hydrolase |
multiple interactions increases chemical synthesis |
EXP |
Nitroglycerin promotes the reaction [FAAH protein results in increased chemical synthesis of Arachidonic Acid] |
CTD |
PMID:19515121 |
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NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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G |
Fadd |
Fas associated via death domain |
multiple interactions |
ISO |
FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP3 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP8 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased cleavage of BID protein] |
CTD |
PMID:19720122 |
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NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fads1 |
fatty acid desaturase 1 |
multiple interactions |
ISO |
[geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid |
CTD |
PMID:16462894 |
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NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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G |
Fads2 |
fatty acid desaturase 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of FADS2 mRNA |
CTD |
PMID:21457203 |
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NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]]; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FAS protein]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein] Arachidonic Acid results in increased expression of FAS mRNA; Arachidonic Acid results in increased expression of FAS protein |
CTD |
PMID:19720122 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
multiple interactions increases expression |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FASLG protein]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein] Arachidonic Acid results in increased expression of FASLG mRNA; Arachidonic Acid results in increased expression of FASLG protein |
CTD |
PMID:19720122 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of FASN mRNA |
CTD |
PMID:19159447 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fgfr3 |
fibroblast growth factor receptor 3 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of FGFR3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression decreases phosphorylation |
ISO |
[Arachidonic Acid co-treated with Quercetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of FOS protein; Arachidonic Acid inhibits the reaction [Quercetin results in increased expression of FOS protein]; Flurbiprofen inhibits the reaction [Arachidonic Acid results in increased expression of FOS mRNA]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of FOS mRNA] Arachidonic Acid results in decreased phosphorylation of FOS protein |
CTD |
PMID:8764118 PMID:10864209 PMID:15878913 PMID:16704987 PMID:19720122 PMID:20551291 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Arachidonic Acid results in increased expression of FOSL1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Gap43 |
growth associated protein 43 |
increases phosphorylation |
ISO |
Arachidonic Acid results in increased phosphorylation of GAP43 protein |
CTD |
PMID:9852580 |
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NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression increases activity |
ISO |
Arachidonic Acid results in increased expression of GCLC mRNA Arachidonic Acid results in increased activity of GCLC protein |
CTD |
PMID:16704987 PMID:17092368 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO EXP |
Arachidonic Acid results in increased expression of GCLM mRNA Arachidonic Acid metabolite results in increased expression of GCLM mRNA |
CTD |
PMID:16704987 PMID:27012417 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Glrx |
glutaredoxin |
affects response to substance |
ISO |
GLRX protein affects the susceptibility to Arachidonic Acid |
CTD |
PMID:19373248 |
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NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gnpda1 |
glucosamine-6-phosphate deaminase 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of GNPDA1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of ALT protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of ALT protein] |
CTD |
PMID:27916511 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
[Iodoacetates results in decreased activity of GPX1 protein] which affects the metabolism of Arachidonic Acid |
CTD |
PMID:11115402 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
[Iodoacetates results in decreased activity of GPX4 protein] which affects the metabolism of Arachidonic Acid; Arachidonic Acid promotes the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein] |
CTD |
PMID:11115402 PMID:14642406 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
[SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron] |
CTD |
PMID:19620254 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of HMGCR mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions decreases response to substance |
ISO EXP |
Arachidonic Acid results in increased expression of HMOX1 mRNA Arachidonic Acid metabolite results in increased expression of HMOX1 mRNA; Arachidonic Acid metabolite results in increased expression of HMOX1 protein NFE2L2 gene mutant form inhibits the reaction [Arachidonic Acid metabolite results in increased expression of HMOX1 protein] HMOX1 protein results in decreased susceptibility to Arachidonic Acid |
CTD |
PMID:15036350 PMID:16704987 PMID:17092368 PMID:27012417 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hs2st1 |
heparan sulfate 2-O-sulfotransferase 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of HS2ST1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:16623957 |
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NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
multiple interactions |
ISO |
Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] |
CTD |
PMID:11356925 |
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NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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G |
Id3 |
inhibitor of DNA binding 3 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ID3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of IDI1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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G |
Ift25 |
intraflagellar transport 25 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of IFT25 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of IGFBP7 mRNA |
CTD |
PMID:16704987 |
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NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] |
CTD |
PMID:15684433 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[IL1A protein co-treated with Arachidonic Acid] results in increased abundance of Dinoprostone |
CTD |
PMID:11351503 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[Arachidonic Acid results in increased abundance of Dinoprostone] promotes the reaction [IL1B protein results in increased expression of PTGS2 protein] |
CTD |
PMID:11112151 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
[IL4 protein co-treated with Arachidonic Acid] results in increased activity of ALOX15 protein; [IL4 protein co-treated with Arachidonic Acid] results in increased expression of ALOX15 mRNA |
CTD |
PMID:11861792 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
increases secretion |
ISO |
Arachidonic Acid results in increased secretion of IL6 protein |
CTD |
PMID:20436887 PMID:21457203 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ilvbl |
ilvB acetolactate synthase like |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ILVBL mRNA |
CTD |
PMID:16704987 |
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NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924
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G |
Ins2 |
insulin 2 |
increases secretion multiple interactions |
ISO |
Arachidonic Acid results in increased secretion of INS protein Arachidonic Acid promotes the reaction [Glucose results in increased secretion of INS protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Arachidonic Acid results in increased secretion of INS protein]; phenidone promotes the reaction [Arachidonic Acid results in increased secretion of INS protein] |
CTD |
PMID:17192482 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Isl1 |
ISL LIM homeobox 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of ISL1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
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G |
Itga2b |
integrin subunit alpha 2b |
increases expression multiple interactions |
ISO |
Arachidonic Acid results in increased expression of ITGA2B protein Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]] |
CTD |
PMID:18413191 |
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NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
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G |
Itga6 |
integrin subunit alpha 6 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of ITGA6 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
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G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions increases expression |
ISO |
Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]]; Quercetin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein] |
CTD |
PMID:18413191 PMID:23249183 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Arachidonic Acid results in increased expression of JUN mRNA Arachidonic Acid results in increased expression of and results in increased phosphorylation of JUN protein; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FAS protein]; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FASLG protein] |
CTD |
PMID:8764118 PMID:16704987 PMID:19720122 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Arachidonic Acid analog results in increased expression of JUNB mRNA] Arachidonic Acid results in increased expression of JUNB mRNA |
CTD |
PMID:8764118 |
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Kcnk10 |
potassium two pore domain channel subfamily K member 10 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [KCNK10 protein results in increased transport of Potassium] |
CTD |
PMID:16075240 |
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NCBI chr 6:117,690,052...117,826,120
Ensembl chr 6:117,694,222...117,825,695
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G |
Kcnk2 |
potassium two pore domain channel subfamily K member 2 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [KCNK2 protein results in increased transport of Potassium] |
CTD |
PMID:16075240 |
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NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
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G |
Kcnk4 |
potassium two pore domain channel subfamily K member 4 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [KCNK4 protein results in increased transport of Potassium] |
CTD |
PMID:10767409 PMID:16075240 |
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NCBI chr 1:204,117,941...204,129,494
Ensembl chr 1:204,114,572...204,125,925
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G |
Klf5 |
KLF transcription factor 5 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of KLF5 mRNA |
CTD |
PMID:16704987 |
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NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
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G |
Klf6 |
KLF transcription factor 6 |
increases expression multiple interactions |
ISO |
Arachidonic Acid results in increased expression of KLF6 mRNA; Arachidonic Acid results in increased expression of KLF6 mRNA alternative form; Arachidonic Acid results in increased expression of KLF6 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; [Arachidonic Acid co-treated with Hydrogen Peroxide] results in increased expression of KLF6 protein; [Arachidonic Acid co-treated with SB 203580] results in decreased expression of KLF6 mRNA; [Arachidonic Acid co-treated with Vitamin K 3] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Hydrogen Peroxide co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; allyl sulfide inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; allyl sulfide inhibits the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]; allyl sulfide inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Arachidonic Acid inhibits the reaction [CYP2E1 protein results in decreased expression of KLF6 mRNA alternative form]; Arachidonic Acid inhibits the reaction [pyrazolanthrone results in decreased expression of KLF6 mRNA]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]; CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]; pyrazolanthrone inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; SB 203580 promotes the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Wortmannin inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]] |
CTD |
PMID:22486562 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Kng1 |
kininogen 1 |
multiple interactions |
ISO |
Arachidonic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA] |
CTD |
PMID:15307955 |
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NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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G |
Krt18 |
keratin 18 |
multiple interactions |
ISO |
[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein |
CTD |
PMID:17034788 |
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NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
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G |
Krt8 |
keratin 8 |
multiple interactions |
ISO |
[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein |
CTD |
PMID:17034788 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of LAMP2 mRNA |
CTD |
PMID:16623957 |
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NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions decreases response to substance |
ISO |
Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; dazoxiben inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]; tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid]; dazoxiben inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid]; Indomethacin promotes the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid] |
CTD |
PMID:20530721 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lep |
leptin |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of LEP mRNA] |
CTD |
PMID:19063610 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipc |
lipase C, hepatic type |
decreases abundance multiple interactions |
ISO |
LIPC gene mutant form results in decreased abundance of Arachidonic Acid [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Arachidonic Acid |
CTD |
PMID:24777581 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance multiple interactions |
ISO |
LIPG gene mutant form results in decreased abundance of Arachidonic Acid [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Arachidonic Acid |
CTD |
PMID:24777581 |
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NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lrat |
lecithin retinol acyltransferase |
increases expression |
EXP |
Arachidonic Acid results in increased expression of LRAT mRNA |
CTD |
PMID:12576510 |
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NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
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G |
Lss |
lanosterol synthase |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of LSS mRNA |
CTD |
PMID:16704987 |
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NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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G |
Ltb4r |
leukotriene B4 receptor |
affects response to substance |
ISO |
LTB4R1 protein affects the susceptibility to Arachidonic Acid |
CTD |
PMID:10934231 |
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NCBI chr15:29,263,199...29,265,716
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G |
Luc7l3 |
LUC7-like 3 pre-mRNA splicing factor |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of LUC7L3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538
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G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Arachidonic Acid results in increased expression of MAFF mRNA |
CTD |
PMID:16704987 |
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NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions |
ISO |
FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein] |
CTD |
PMID:19720122 |
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NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation affects abundance multiple interactions |
ISO EXP |
Arachidonic Acid results in increased phosphorylation of MAPK1 protein MAPK1 protein affects the abundance of Arachidonic Acid [Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein]; CYP2C23 mRNA promotes the reaction [Arachidonic Acid results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:16216387 PMID:19464254 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO EXP |
MAPK14 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein] MAPK14 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid] |
CTD |
PMID:16120751 PMID:19540902 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions affects abundance increases phosphorylation |
ISO EXP |
[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein]; CYP2C23 mRNA promotes the reaction [Arachidonic Acid results in increased phosphorylation of MAPK3 protein] MAPK3 protein affects the abundance of Arachidonic Acid |
CTD |
PMID:16216387 PMID:19464254 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein] |
CTD |
PMID:19540902 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapt |
microtubule-associated protein tau |
increases phosphorylation multiple interactions |
ISO |
Arachidonic Acid results in increased phosphorylation of MAPT protein Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein] |
CTD |
PMID:12605413 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Mmp13 |
matrix metallopeptidase 13 |
increases secretion multiple interactions increases expression |
ISO |
Arachidonic Acid results in increased secretion of MMP13 protein Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP13 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP13 protein] |
CTD |
PMID:16185265 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression increases secretion |
ISO |
Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP2 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP2 protein] |
CTD |
PMID:16185265 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression multiple interactions increases secretion |
ISO |
Arachidonic Acid results in increased expression of MMP9 mRNA Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP9 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP9 protein] |
CTD |
PMID:16185265 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
increases secretion multiple interactions increases expression |
ISO |
Arachidonic Acid results in increased secretion of MPO protein 5-((1,5-bis(4-methoxyphenyl)pyrazol-3-yl)dimethoxymethyl)-2-chlorobenzamide inhibits the reaction [Arachidonic Acid results in increased expression of MPO protein] |
CTD |
PMID:3111576 PMID:9831321 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mt2A |
metallothionein 2A |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA] |
CTD |
PMID:12566070 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
[Quercetin co-treated with Arachidonic Acid] results in decreased phosphorylation of MTOR protein |
CTD |
PMID:20551291 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions increases localization |
ISO |
Adiponectin inhibits the reaction [Arachidonic Acid results in increased localization of NCF1 protein]; Arachidonic Acid affects the reaction [Zymosan analog affects the localization of NCF1 protein] |
CTD |
PMID:12101222 PMID:20832062 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions |
ISO |
Arachidonic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein] |
CTD |
PMID:12101222 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
EXP |
NFE2L2 gene mutant form inhibits the reaction [Arachidonic Acid metabolite results in increased expression of HMOX1 protein] Arachidonic Acid metabolite results in increased expression of NFE2L2 protein |
CTD |
PMID:27012417 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
ISO |
Arachidonic Acid results in increased cleavage of and results in increased secretion of NOX1 protein; Cholesterol, LDL affects the reaction [Adiponectin inhibits the reaction [Arachidonic Acid results in increased cleavage of NOX1 protein]] |
CTD |
PMID:20832062 |
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NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
EXP |
Arachidonic Acid metabolite results in increased expression of NQO1 mRNA |
CTD |
PMID:27012417 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects binding multiple interactions |
ISO |
Arachidonic Acid binds to NR1H4 protein Arachidonic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] |
CTD |
PMID:15307955 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr2f1 |
nuclear receptor subfamily 2, group F, member 1 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of NR2F1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of NR4A2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nr5a2 |
nuclear receptor subfamily 5, group A, member 2 |
multiple interactions decreases chemical synthesis |
ISO |
[NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in decreased abundance of Arachidonic Acid analog NR5A2 gene mutant form results in decreased chemical synthesis of Arachidonic Acid |
CTD |
PMID:29515023 |
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NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
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G |
Nrtn |
neurturin |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of NRTN mRNA |
CTD |
PMID:16704987 |
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NCBI chr 9:1,581,860...1,587,835
Ensembl chr 9:1,581,975...1,583,102
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases cleavage |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased cleavage of PARP1 protein]; [Arachidonic Acid co-treated with Iron] results in increased expression of PARP1 protein modified form; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of PARP1 protein modified form] |
CTD |
PMID:10403056 PMID:19540902 PMID:21132278 PMID:30626086 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pde4dip |
phosphodiesterase 4D interacting protein |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of PDE4DIP mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
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G |
Pdss2 |
decaprenyl diphosphate synthase subunit 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of PDSS2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
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G |
Phlda1 |
pleckstrin homology-like domain, family A, member 1 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of PHLDA1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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G |
Pla2g4a |
phospholipase A2 group IVA |
multiple interactions increases expression |
ISO EXP |
AHR affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [PLA2G4A protein results in increased secretion of Arachidonic Acid]]; Dinoprostone promotes the reaction [Arachidonic Acid results in increased expression of PLA2G4A mRNA]; Flurbiprofen inhibits the reaction [Arachidonic Acid results in increased expression of PLA2G4A mRNA] PLA2G4A protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid] Arachidonic Acid results in increased expression of PLA2G4A mRNA; Arachidonic Acid results in increased expression of PLA2G4A protein |
CTD |
PMID:15878913 PMID:16120751 PMID:19162293 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Pla2g5 |
phospholipase A2, group V |
multiple interactions |
ISO |
PLA2G5 protein promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Arachidonic Acid] |
CTD |
PMID:9495842 |
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NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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G |
Pla2g6 |
phospholipase A2 group VI |
multiple interactions |
EXP |
PLA2G6 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid] |
CTD |
PMID:16120751 |
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NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
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G |
Plaa |
phospholipase A2, activating protein |
multiple interactions |
ISO |
PLAA protein promotes the reaction [Lipopolysaccharides results in increased abundance of Arachidonic Acid] |
CTD |
PMID:11094054 |
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NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
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G |
Plin2 |
perilipin 2 |
increases expression |
ISO EXP |
Arachidonic Acid results in increased expression of PLIN2 mRNA Arachidonic Acid results in increased expression of PLIN2 mRNA; Arachidonic Acid results in increased expression of PLIN2 protein |
CTD |
PMID:16489205 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of PMAIP1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] Arachidonic Acid results in decreased activity of PON1 protein |
CTD |
PMID:15375178 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression multiple interactions |
ISO |
Arachidonic Acid results in increased expression of PPARA mRNA; Arachidonic Acid results in increased expression of PPARA protein Arachidonic Acid binds to and results in increased activity of PPARA protein |
CTD |
PMID:10403814 PMID:11172467 PMID:15491415 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression |
ISO |
Arachidonic Acid results in increased expression of PPARD mRNA |
CTD |
PMID:11172467 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression increases expression multiple interactions |
ISO EXP |
Arachidonic Acid results in decreased expression of PPARG mRNA; Arachidonic Acid results in decreased expression of PPARG protein Arachidonic Acid results in increased expression of PPARG protein Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG mRNA] |
CTD |
PMID:11172467 PMID:12604186 PMID:19063610 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppp1ca |
protein phosphatase 1 catalytic subunit alpha |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of PPP1CA mRNA |
CTD |
PMID:16623957 |
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NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
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G |
Prpf4 |
pre-mRNA splicing tri-snRNP complex factor 4 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of PRPF4 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 5:75,859,934...75,873,924
Ensembl chr 5:75,859,924...75,873,919
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G |
Psat1 |
phosphoserine aminotransferase 1 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of PSAT1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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G |
Ptafr |
platelet-activating factor receptor |
multiple interactions |
EXP |
[Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of PTAFR mRNA; Arachidonic Acid inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of PTAFR mRNA] |
CTD |
PMID:17515866 |
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NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
increases activity increases response to substance increases metabolic processing multiple interactions |
ISO |
Arachidonic Acid results in increased activity of PTGS1 protein PTGS1 results in increased susceptibility to Arachidonic Acid PTGS1 protein alternative form results in increased metabolism of Arachidonic Acid; PTGS1 protein results in increased metabolism of Arachidonic Acid [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine; [Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine; [PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of 12-hydroxy-5,8,10-heptadecatrienoic acid; [PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of Thromboxane B2; arzanol inhibits the reaction [[PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of 12-hydroxy-5,8,10-heptadecatrienoic acid]; arzanol inhibits the reaction [[PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of Thromboxane B2]; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; DuP 697 inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; Resveratrol inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; SC 560 inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; valerylsalicylate inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein] |
CTD |
PMID:15863457 PMID:16141368 PMID:19751497 PMID:20933508 PMID:21163909 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases metabolic processing increases response to substance increases activity |
ISO EXP |
[[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased abundance of Dinoprostone] promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]; [Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine; [Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine; [lenabasum results in increased expression of PTGS2 mRNA] which results in increased secretion of Arachidonic Acid; [PTGS2 co-treated with Arachidonic Acid] results in increased expression of VEGFA; Arachidonic Acid inhibits the reaction [5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulfonyl)phenyl-2(5H)-furanone binds to and results in decreased activity of PTGS2 protein]; Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [Arachidonic Acid results in increased activity of PTGS2 protein]; Dinoprostone promotes the reaction [Arachidonic Acid results in increased expression of PTGS2 mRNA]; Flurbiprofen inhibits the reaction [Arachidonic Acid results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]; nimesulide inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid] Arachidonic Acid results in increased expression of PTGS2 protein PTGS2 results in increased susceptibility to Arachidonic Acid 12-HPETE inhibits the reaction [Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]]; 2-methoxybenzoic acid inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]; [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid; [nimesulide results in decreased expression of PTGS2] which results in increased abundance of Arachidonic Acid; [PTGS2 protein results in increased abundance of prostaglandin G2] inhibits the reaction [Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]]; Arachidonic Acid affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Benzoic Acid inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]; Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid]; Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid] Arachidonic Acid results in increased expression of PTGS2 mRNA; Arachidonic Acid results in increased expression of PTGS2 protein |
CTD |
PMID:9013627 PMID:9146894 PMID:11112151 PMID:12538810 PMID:12757841 PMID:12821125 PMID:15684433 PMID:15863457 PMID:15878913 PMID:17092368 PMID:17624748 PMID:18297109 PMID:18388244 PMID:18840450 PMID:19063610 PMID:21163909 PMID:22476691 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptp4a1 |
protein tyrosine phosphatase 4A1 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of PTP4A1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
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G |
Rapgef2 |
Rap guanine nucleotide exchange factor 2 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of RAPGEF2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
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G |
Retn |
resistin |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of RETN mRNA |
CTD |
PMID:15949695 |
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NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:20551291 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Rxra |
retinoid X receptor alpha |
affects binding |
ISO |
Arachidonic Acid binds to RXRA protein |
CTD |
PMID:16258897 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Scd |
stearoyl-CoA desaturase |
increases expression |
ISO |
Arachidonic Acid results in increased expression of SCD mRNA |
CTD |
PMID:21457203 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Selp |
selectin P |
increases expression multiple interactions |
ISO |
Arachidonic Acid results in increased expression of SELP protein Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]]; Quercetin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein] |
CTD |
PMID:17543677 PMID:18413191 PMID:23249183 |
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NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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G |
Serpinb2 |
serpin family B member 2 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of SERPINB2 mRNA |
CTD |
PMID:18388244 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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G |
Skp2 |
S-phase kinase associated protein 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of SKP2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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G |
Slc4a2 |
solute carrier family 4 member 2 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of SLC4A2 mRNA |
CTD |
PMID:16623957 |
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NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of SLC7A11 mRNA |
CTD |
PMID:16704987 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Snai2 |
snail family transcriptional repressor 2 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of SNAI2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS3 mRNA] |
CTD |
PMID:19063610 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
decreases activity increases activity multiple interactions |
EXP |
Arachidonic Acid results in decreased activity of SOD1 protein Arachidonic Acid results in increased activity of SOD1 protein 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Arachidonic Acid results in decreased activity of SOD1 protein]; Indomethacin inhibits the reaction [Arachidonic Acid results in decreased activity of SOD1 protein] |
CTD |
PMID:16982041 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases activity increases expression |
ISO EXP |
[Arachidonic Acid results in increased abundance of Reactive Oxygen Species] which results in increased expression of SOD2; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Arachidonic Acid results in increased expression of and results in increased activity of SOD2 protein; calphostin C inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Dactinomycin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Indomethacin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Indomethacin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Masoprocol inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Masoprocol inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Phenols inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein] Arachidonic Acid results in increased activity of SOD2 protein 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Arachidonic Acid results in increased activity of SOD2 protein]; Indomethacin inhibits the reaction [Arachidonic Acid results in increased activity of SOD2 protein] |
CTD |
PMID:12031898 PMID:16982041 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sox9 |
SRY-box transcription factor 9 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of SOX9 mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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G |
Sparc |
secreted protein acidic and cysteine rich |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of SPARC mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Spast |
spastin |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of SPAST mRNA |
CTD |
PMID:16704987 |
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NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
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G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of SQSTM1 mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Srgap2 |
SLIT-ROBO Rho GTPase activating protein 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of SRGAP2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr13:42,745,956...42,967,091
Ensembl chr13:42,745,947...42,967,058
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G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
EXP |
Arachidonic Acid metabolite results in increased expression of SRXN1 mRNA |
CTD |
PMID:27012417 |
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NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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G |
Ssr2 |
signal sequence receptor subunit 2 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of SSR2 mRNA |
CTD |
PMID:16623957 |
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NCBI chr 2:174,048,291...174,057,043
Ensembl chr 2:174,048,460...174,057,042
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G |
Star |
steroidogenic acute regulatory protein |
increases expression multiple interactions |
EXP |
Arachidonic Acid results in increased expression of STAR protein Arachidonic Acid inhibits the reaction [Dimethoate results in decreased expression of STAR protein] |
CTD |
PMID:22476691 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stc2 |
stanniocalcin 2 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of STC2 mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
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G |
Stk11 |
serine/threonine kinase 11 |
multiple interactions |
ISO |
STK11 protein affects the reaction [resveratrol results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]] |
CTD |
PMID:19620254 |
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NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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G |
Tfeb |
transcription factor EB |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of TFEB mRNA |
CTD |
PMID:16623957 |
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NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA] |
CTD |
PMID:16581302 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Thrsp |
thyroid hormone responsive |
decreases expression multiple interactions |
ISO |
Arachidonic Acid results in decreased expression of THRSP mRNA Flurbiprofen inhibits the reaction [Arachidonic Acid results in decreased expression of THRSP mRNA] |
CTD |
PMID:10357836 |
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NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
EXP |
[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] |
CTD |
PMID:16581302 |
|
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
EXP |
[Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of TLR4 mRNA; Arachidonic Acid inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA] |
CTD |
PMID:17515866 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases abundance increases secretion |
ISO |
Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased secretion of Arachidonic Acid] TNF protein results in increased abundance of Arachidonic Acid Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]; TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]] |
CTD |
PMID:1515551 PMID:10588948 PMID:15684433 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf12a |
TNF receptor superfamily member 12A |
increases expression |
ISO |
Arachidonic Acid results in increased expression of TNFRSF12A mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]] |
CTD |
PMID:10588948 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tns3 |
tensin 3 |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of TNS3 mRNA |
CTD |
PMID:16704987 |
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NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
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G |
Top2a |
DNA topoisomerase II alpha |
decreases expression |
ISO |
Arachidonic Acid results in decreased expression of TOP2A mRNA |
CTD |
PMID:16704987 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
[TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Arachidonic Acid [TP53 protein results in increased expression of ALOX12B mRNA] which results in increased metabolism of Arachidonic Acid; [TP53 protein results in increased expression of ALOX5 mRNA] which results in increased metabolism of Arachidonic Acid |
CTD |
PMID:30258081 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
increases activity multiple interactions |
ISO |
Arachidonic Acid results in increased activity of TRPA1 protein Ruthenium Red inhibits the reaction [Arachidonic Acid results in increased activity of TRPA1 protein] |
CTD |
PMID:15046718 |
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NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
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G |
Trpc4 |
transient receptor potential cation channel, subfamily C, member 4 |
multiple interactions |
ISO |
TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium] |
CTD |
PMID:11830588 |
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NCBI chr 2:138,307,676...138,476,856
Ensembl chr 2:138,308,084...138,476,768
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
EXP |
[Arachidonic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein |
CTD |
PMID:17038422 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases activity |
ISO |
Arachidonic Acid results in increased activity of TRPV4 protein |
CTD |
PMID:20956320 |
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NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases glucuronidation |
ISO |
UGT1A1 protein results in increased glucuronidation of Arachidonic Acid |
CTD |
PMID:15231852 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
increases glucuronidation |
ISO |
UGT1A3 protein results in increased glucuronidation of Arachidonic Acid |
CTD |
PMID:15231852 |
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NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a5 |
UDP glucuronosyltransferase family 1 member A5 |
increases glucuronidation |
ISO |
UGT1A4 protein results in increased glucuronidation of Arachidonic Acid |
CTD |
PMID:15231852 |
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NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
increases glucuronidation |
ISO |
UGT1A9 protein results in increased glucuronidation of Arachidonic Acid |
CTD |
PMID:15231852 |
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NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt2b7 |
UDP glucuronosyltransferase family 2 member B7 |
increases glucuronidation |
ISO |
UGT2B7 protein results in increased glucuronidation of Arachidonic Acid |
CTD |
PMID:15231852 |
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NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression |
ISO |
[PTGS2 co-treated with Arachidonic Acid] results in increased expression of VEGFA [Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein; [Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein]; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein] Arachidonic Acid results in increased expression of VEGFA mRNA |
CTD |
PMID:12821125 PMID:18388244 PMID:19464254 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Ywhaz |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
increases expression |
ISO |
Arachidonic Acid results in increased expression of YWHAZ mRNA |
CTD |
PMID:16704987 |
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NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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G |
Zfp36 |
zinc finger protein 36 |
increases expression |
ISO |
Arachidonic Acid results in increased expression of ZFP36 mRNA |
CTD |
PMID:8764118 |
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NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Agrp |
agouti related neuropeptide |
decreases expression |
EXP |
arachidonyl-2-chloroethylamide results in decreased expression of AGRP mRNA |
CTD |
PMID:26468265 |
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NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
ISO |
arachidonyl-2-chloroethylamide results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:26847930 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Angpt1 |
angiopoietin 1 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of ANGPT1 protein] |
CTD |
PMID:26467187 |
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NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
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G |
Angpt2 |
angiopoietin 2 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of ANGPT2 protein] |
CTD |
PMID:26467187 |
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NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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G |
Avp |
arginine vasopressin |
multiple interactions |
EXP |
arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA] |
CTD |
PMID:26468265 |
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NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein arachidonyl-2-chloroethylamide results in increased expression of BCL2 protein |
CTD |
PMID:30607903 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Cartpt |
CART prepropeptide |
decreases expression multiple interactions |
EXP |
arachidonyl-2-chloroethylamide results in decreased expression of CARTPT mRNA [arachidonyl-2-chloroethylamide co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA |
CTD |
PMID:26468265 |
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NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] |
CTD |
PMID:31256211 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein] |
CTD |
PMID:31256211 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA] |
CTD |
PMID:29033935 |
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Cd86 |
CD86 molecule |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA] |
CTD |
PMID:29033935 |
|
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
EXP ISO |
CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK3 protein] CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein] |
CTD |
PMID:12734338 PMID:27455076 PMID:29033935 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Dagla |
diacylglycerol lipase, alpha |
multiple interactions increases expression |
ISO |
ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA] arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLA promoter]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA protein]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA] arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA; arachidonyl-2-chloroethylamide results in increased expression of DAGLA protein |
CTD |
PMID:31912162 |
|
NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
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G |
Daglb |
diacylglycerol lipase, beta |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA] arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLB promoter]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA] |
CTD |
PMID:31912162 |
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NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein] |
CTD |
PMID:31256211 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Drd2 |
dopamine receptor D2 |
decreases expression |
EXP |
arachidonyl-2-chloroethylamide results in decreased expression of DRD2 mRNA |
CTD |
PMID:22791651 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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G |
Esrrg |
estrogen-related receptor gamma |
increases expression multiple interactions |
ISO EXP |
arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA; arachidonyl-2-chloroethylamide results in increased expression of ESRRG protein ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA] arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLA promoter]; arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLB promoter]; arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to FGF21 promoter]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA protein]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein] |
CTD |
PMID:27455076 PMID:30019168 PMID:31912162 |
|
NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G |
Fga |
fibrinogen alpha chain |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of FGA mRNA GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGA mRNA] |
CTD |
PMID:30019168 |
|
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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G |
Fgb |
fibrinogen beta chain |
multiple interactions increases expression |
ISO |
GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGB mRNA] |
CTD |
PMID:30019168 |
|
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf21 |
fibroblast growth factor 21 |
increases expression increases secretion multiple interactions |
ISO EXP |
arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to FGF21 promoter]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein] ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA] arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA; arachidonyl-2-chloroethylamide results in increased expression of FGF21 protein |
CTD |
PMID:27455076 |
|
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgg |
fibrinogen gamma chain |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of FGG mRNA GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGG mRNA] |
CTD |
PMID:30019168 |
|
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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G |
Foxo1 |
forkhead box O1 |
multiple interactions decreases phosphorylation |
ISO |
FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of TFAM mRNA] arachidonyl-2-chloroethylamide results in decreased phosphorylation of FOXO1 protein |
CTD |
PMID:26847930 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] |
CTD |
PMID:26847930 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein results in increased activity of GSR protein] |
CTD |
PMID:26671069 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Hcrt |
hypocretin neuropeptide precursor |
increases expression |
EXP |
arachidonyl-2-chloroethylamide results in increased expression of HCRT mRNA |
CTD |
PMID:26468265 |
|
NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA] |
CTD |
PMID:29033935 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
[arachidonyl-2-chloroethylamide co-treated with Glucose] results in increased secretion of INS1 protein; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein results in increased activity of GSR protein]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] |
CTD |
PMID:26671069 PMID:26847930 PMID:30761839 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK1 protein]; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK1 protein] arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:12734338 PMID:19477951 PMID:26467187 PMID:29033935 PMID:30607903 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK3 protein]; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK3 protein] arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:12734338 PMID:19477951 PMID:26467187 PMID:29033935 PMID:30607903 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mpo |
myeloperoxidase |
multiple interactions increases activity |
ISO |
Acetylcysteine inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]; SB 203580 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein] |
CTD |
PMID:32033504 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions decreases expression |
ISO |
FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NFE2L2 mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 protein]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 protein]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 protein] |
CTD |
PMID:29033935 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions decreases expression |
ISO |
FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Oxt |
oxytocin/neurophysin I prepropeptide |
multiple interactions |
EXP |
arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA]; arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased secretion of OXT protein] |
CTD |
PMID:26468265 |
|
NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] |
CTD |
PMID:31256211 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] |
CTD |
PMID:26847930 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pmch |
pro-melanin-concentrating hormone |
multiple interactions increases expression |
EXP |
arachidonyl-2-chloroethylamide promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of PMCH mRNA] arachidonyl-2-chloroethylamide results in increased expression of PMCH mRNA |
CTD |
PMID:26468265 |
|
NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
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G |
Pomc |
proopiomelanocortin |
multiple interactions decreases expression |
EXP |
arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA] arachidonyl-2-chloroethylamide results in decreased expression of POMC mRNA |
CTD |
PMID:26468265 |
|
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions decreases expression |
ISO |
FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of PPARGC1A mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions affects localization |
ISO |
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide affects the localization of RELA protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide affects the localization of RELA protein]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide affects the localization of RELA protein] |
CTD |
PMID:29033935 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Rhoa |
ras homolog family member A |
multiple interactions increases activity |
ISO |
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of RHOA protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of RHOA protein] |
CTD |
PMID:29033935 |
|
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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G |
Tfam |
transcription factor A, mitochondrial |
decreases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in decreased expression of TFAM mRNA FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions |
ISO |
arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA; arachidonyl-2-chloroethylamide results in increased expression of TNF protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein] |
CTD |
PMID:29033935 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased phosphorylation of TRP53 protein] |
CTD |
PMID:31256211 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein] |
CTD |
PMID:26467187 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfc |
vascular endothelial growth factor C |
multiple interactions |
ISO |
AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein] |
CTD |
PMID:26467187 |
|
NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
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G |
Pafah1b1 |
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 |
increases expression multiple interactions |
EXP |
Castor Oil results in increased expression of PAFAH1B1 protein isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein] |
CTD |
PMID:1354728 PMID:2743081 PMID:8738301 |
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NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl arachidonate |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions decreases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl arachidonate LIPG gene mutant form results in decreased abundance of cholesteryl arachidonate |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions increases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate LIPG gene mutant form results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
affects expression |
EXP |
Corn Oil affects the expression of ABCG8 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
EXP |
Corn Oil results in increased expression of ACACA mRNA |
CTD |
PMID:1973097 |
|
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acly |
ATP citrate lyase |
affects expression |
EXP |
Corn Oil affects the expression of ACLY mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Acot2 |
acyl-CoA thioesterase 2 |
affects expression |
EXP |
Corn Oil affects the expression of ACOT2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
EXP |
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein] |
CTD |
PMID:29165388 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Akr1b7 |
aldo-keto reductase family 1, member B7 |
affects expression |
EXP |
Corn Oil affects the expression of AKR1B7 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
affects expression |
EXP |
Corn Oil affects the expression of ALDH1A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Angptl4 |
angiopoietin-like 4 |
affects expression |
EXP |
Corn Oil affects the expression of ANGPTL4 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA |
CTD |
PMID:32186404 |
|
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Bad |
BCL2-associated agonist of cell death |
increases expression |
EXP |
Corn Oil results in increased expression of BAD mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
affects expression |
EXP |
Corn Oil affects the expression of BHLHE40 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
affects expression |
EXP |
Corn Oil affects the expression of BHMT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Corn Oil results in increased expression of BIRC3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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|
G |
Bmp1 |
bone morphogenetic protein 1 |
affects expression |
EXP |
Corn Oil affects the expression of BMP1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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|
G |
Cadm1 |
cell adhesion molecule 1 |
affects expression |
EXP |
Corn Oil affects the expression of CADM1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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|
G |
Calca |
calcitonin-related polypeptide alpha |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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|
G |
Car6 |
carbonic anhydrase 6 |
increases expression |
ISO |
Corn Oil results in increased expression of CAR6 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
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|
G |
Card9 |
caspase recruitment domain family, member 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CARD9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
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|
G |
Cat |
catalase |
multiple interactions decreases expression |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein Corn Oil results in decreased expression of CAT protein |
CTD |
PMID:36432690 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Cav3 |
caveolin 3 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CAV3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
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|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression decreases expression |
ISO EXP |
Corn Oil results in increased expression of CCL3 mRNA Corn Oil results in decreased expression of CCL3 mRNA |
CTD |
PMID:22760963 PMID:23409006 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccnd1 |
cyclin D1 |
affects expression |
EXP |
Corn Oil affects the expression of CCND1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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|
G |
Cd36 |
CD36 molecule |
decreases expression |
EXP |
Corn Oil results in decreased expression of CD36 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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|
G |
Cdhr1 |
cadherin-related family member 1 |
increases expression |
EXP |
Corn Oil results in increased expression of CDHR1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
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|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
affects expression increases expression |
EXP |
Corn Oil affects the expression of CDKN1A mRNA Corn Oil results in increased expression of CDKN1A mRNA |
CTD |
PMID:16360708 PMID:22760963 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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|
G |
Cenpt |
centromere protein T |
increases expression |
EXP |
Corn Oil results in increased expression of CENPT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
|
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G |
Cfb |
complement factor B |
increases expression |
EXP |
Corn Oil results in increased expression of CFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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|
G |
Cldn1 |
claudin 1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CLDN1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
|
|
G |
Cldn9 |
claudin 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CLDN9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr10:12,714,137...12,715,568
|
|
G |
Cox7a1 |
cytochrome c oxidase subunit 7A1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of COX7A1 mRNA |
CTD |
PMID:23409006 |
|
NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions affects expression |
EXP ISO |
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA |
CTD |
PMID:16360708 PMID:22760963 PMID:36432690 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
|
|
G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
|
|
G |
Crot |
carnitine O-octanoyltransferase |
affects expression multiple interactions |
EXP ISO |
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA |
CTD |
PMID:16360708 PMID:36432690 |
|
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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G |
Ctsg |
cathepsin G |
increases expression |
EXP |
Corn Oil results in increased expression of CTSG mRNA |
CTD |
PMID:22760963 |
|
NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP17A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP7A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP8B1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
|
|
G |
Ephx2 |
epoxide hydrolase 2 |
affects expression |
EXP |
Corn Oil affects the expression of EPHX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
|
|
G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
decreases expression |
EXP |
Corn Oil results in decreased expression of ETS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
|
|
G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions |
EXP |
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA |
CTD |
PMID:15016835 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
|
|
G |
Fabp2 |
fatty acid binding protein 2 |
affects expression |
EXP |
Corn Oil affects the expression of FABP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
|
|
G |
Fabp7 |
fatty acid binding protein 7 |
affects expression |
EXP |
Corn Oil affects the expression of FABP7 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
|
|
G |
Fasn |
fatty acid synthase |
affects expression |
EXP |
Corn Oil affects the expression of FASN mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
|
|
G |
Fcgrt |
Fc gamma receptor and transporter |
decreases expression |
EXP |
Corn Oil results in decreased expression of FCGRT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
|
|
G |
Fgb |
fibrinogen beta chain |
affects expression |
EXP |
Corn Oil affects the expression of FGB mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
|
|
G |
Fgf21 |
fibroblast growth factor 21 |
affects expression |
EXP |
Corn Oil affects the expression of FGF21 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
|
|
G |
Fst |
follistatin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
|
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G |
G0s2 |
G0/G1switch 2 |
affects expression |
EXP |
Corn Oil affects the expression of G0S2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
affects expression |
EXP |
Corn Oil affects the expression of GADD45A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
|
|
G |
Gal |
galanin and GMAP prepropeptide |
increases expression |
EXP |
Corn Oil results in increased expression of GAL mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
|
|
G |
Gck |
glucokinase |
affects expression |
EXP |
Corn Oil affects the expression of GCK mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
|
|
G |
Gjd2 |
gap junction protein, delta 2 |
increases expression |
ISO |
Corn Oil results in increased expression of GJD2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061
|
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
affects expression |
EXP |
Corn Oil affects the expression of GOT1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
|
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
EXP |
Corn Oil results in decreased expression of GOT2 mRNA |
CTD |
PMID:34987138 |
|
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
|
|
G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
affects expression |
EXP |
Corn Oil affects the expression of GPD2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
|
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] |
CTD |
PMID:29479035 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
|
|
G |
H2ac25 |
H2A clustered histone 25 |
affects expression |
EXP |
Corn Oil affects the expression of H2A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
|
|
G |
Hal |
histidine ammonia lyase |
affects expression |
EXP |
Corn Oil affects the expression of HAL mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
|
|
G |
Hamp |
hepcidin antimicrobial peptide |
affects expression |
EXP |
Corn Oil affects the expression of HAMP mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
affects expression |
EXP |
Corn Oil affects the expression of HMGCR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
|
G |
Hoxa11 |
homeobox A11 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
|
|
G |
Hp |
haptoglobin |
increases expression |
EXP |
Corn Oil results in increased expression of HP mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
Corn Oil results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
|
|
G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
affects expression |
EXP |
Corn Oil affects the expression of IDI1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
|
|
G |
Igf2bp2 |
insulin-like growth factor 2 mRNA binding protein 2 |
affects expression increases expression |
EXP |
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
|
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
affects expression |
EXP |
Corn Oil affects the expression of IGFBP1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
|
|
G |
Ihh |
Indian hedgehog signaling molecule |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
|
|
G |
Il12b |
interleukin 12B |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL12B protein |
CTD |
PMID:33263755 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
|
|
G |
Il18 |
interleukin 18 |
increases expression |
ISO |
Corn Oil results in increased expression of IL18 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
|
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G |
Il1a |
interleukin 1 alpha |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL1A protein |
CTD |
PMID:33263755 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
|
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G |
Il1b |
interleukin 1 beta |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL1B protein |
CTD |
PMID:33263755 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
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G |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
EXP |
Corn Oil results in increased expression of IL1RN mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
|
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G |
Il4 |
interleukin 4 |
increases expression increases secretion decreases expression |
ISO EXP |
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA |
CTD |
PMID:23409006 PMID:33263755 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Il6r |
interleukin 6 receptor |
increases expression |
EXP |
Corn Oil results in increased expression of IL6R mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
|
|
G |
Il9 |
interleukin 9 |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL9 protein |
CTD |
PMID:33263755 |
|
NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
|
|
G |
Inhbe |
inhibin subunit beta E |
affects expression |
EXP |
Corn Oil affects the expression of INHBE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
|
|
G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
|
G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of IRAK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
|
|
G |
Irf5 |
interferon regulatory factor 5 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF5 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
|
|
G |
Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Corn Oil results in increased expression of JUN mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
|
|
G |
Klf2 |
KLF transcription factor 2 |
affects expression |
EXP |
Corn Oil affects the expression of KLF2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
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G |
Lcat |
lecithin cholesterol acyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA |
CTD |
PMID:36432690 |
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NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Lcn2 |
lipocalin 2 |
increases expression |
EXP |
Corn Oil results in increased expression of LCN2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lep |
leptin |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein] |
CTD |
PMID:29165388 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lgals1 |
galectin 1 |
increases expression |
EXP |
Corn Oil results in increased expression of LGALS1 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
Corn Oil results in increased activity of and results in increased cleavage of LOX protein |
CTD |
PMID:26240151 |
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NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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G |
Ly75 |
lymphocyte antigen 75 |
increases expression |
EXP |
Corn Oil results in increased expression of LY75 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K1 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K3 mRNA |
CTD |
PMID:33263755 |
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NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
affects expression |
EXP |
Corn Oil affects the expression of MAP2K6 mRNA |
CTD |
PMID:16360708 |
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NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP3K7 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK1 mRNA |
CTD |
PMID:33263755 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK14 mRNA |
CTD |
PMID:33263755 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK3 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
EXP |
Corn Oil results in decreased expression of MDM2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
increases expression |
EXP |
Corn Oil results in increased expression of MGMT mRNA |
CTD |
PMID:22760963 |
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NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mgst2 |
microsomal glutathione S-transferase 2 |
increases expression |
EXP |
Corn Oil results in increased expression of MGST2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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G |
Mlycd |
malonyl-CoA decarboxylase |
decreases expression |
EXP |
Corn Oil results in decreased expression of MLYCD mRNA |
CTD |
PMID:22760963 |
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NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
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G |
Msmo1 |
methylsterol monooxygenase 1 |
affects expression |
EXP |
Corn Oil affects the expression of MSMO1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA |
CTD |
PMID:36432690 |
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NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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G |
Mx2 |
MX dynamin like GTPase 2 |
affects expression |
EXP |
Corn Oil affects the expression of MX2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
increases expression |
ISO |
Corn Oil results in increased expression of MYD88 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases activity |
ISO |
Corn Oil results in decreased activity of NFE2L2 protein |
CTD |
PMID:30203046 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
increases expression |
ISO |
Corn Oil results in increased expression of NFKBIA mRNA |
CTD |
PMID:33263755 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nlrc4 |
NLR family, CARD domain containing 4 |
increases expression |
ISO |
Corn Oil results in increased expression of NLRC4 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Corn Oil affects the expression of NR1H4 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
increases expression |
EXP |
Corn Oil results in increased expression of NR4A2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nsmce3 |
NSE3 homolog, SMC5-SMC6 complex component |
affects expression |
EXP |
Corn Oil affects the expression of NSMCE3 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:118,401,302...118,402,629
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G |
Oat |
ornithine aminotransferase |
affects expression |
EXP |
Corn Oil affects the expression of OAT mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
affects expression |
EXP |
Corn Oil affects the expression of OSGIN1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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G |
P2rx5 |
purinergic receptor P2X 5 |
affects expression |
EXP |
Corn Oil affects the expression of P2RX5 mRNA |
CTD |
PMID:16360708 |
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NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
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G |
Pax8 |
paired box 8 |
affects expression |
EXP |
Corn Oil affects the expression of PAX8 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression |
EXP |
Corn Oil affects the expression of PDGFA mRNA |
CTD |
PMID:16360708 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
increases expression |
EXP |
Corn Oil results in increased expression of PDGFRB mRNA |
CTD |
PMID:22760963 |
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NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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G |
Pdlim1 |
PDZ and LIM domain 1 |
affects expression |
EXP |
Corn Oil affects the expression of PDLIM1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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G |
Pdlim2 |
PDZ and LIM domain 2 |
affects expression |
EXP |
Corn Oil affects the expression of PDLIM2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
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G |
Pgf |
placental growth factor |
increases expression |
EXP |
Corn Oil results in increased expression of PGF mRNA |
CTD |
PMID:22760963 |
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NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
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G |
Pgrmc2 |
progesterone receptor membrane component 2 |
affects expression |
EXP |
Corn Oil affects the expression of PGRMC2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
increases expression |
ISO |
Corn Oil results in increased expression of PIK3CA mRNA |
CTD |
PMID:33263755 |
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NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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G |
Plin2 |
perilipin 2 |
affects expression |
EXP |
Corn Oil affects the expression of PLIN2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Prlr |
prolactin receptor |
affects expression |
EXP |
Corn Oil affects the expression of PRLR mRNA |
CTD |
PMID:16360708 |
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NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA |
CTD |
PMID:32186404 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptprf |
protein tyrosine phosphatase, receptor type, F |
affects expression |
EXP |
Corn Oil affects the expression of PTPRF mRNA |
CTD |
PMID:16360708 |
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NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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G |
Pycard |
PYD and CARD domain containing |
increases expression |
ISO |
Corn Oil results in increased expression of PYCARD mRNA |
CTD |
PMID:33263755 |
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NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Rac1 |
Rac family small GTPase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RAC1 mRNA |
CTD |
PMID:33263755 |
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NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK1 mRNA |
CTD |
PMID:33263755 |
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NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk2 |
receptor-interacting serine-threonine kinase 2 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
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G |
RT1-A |
RT1 class I, locus A |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-A mRNA |
CTD |
PMID:22760963 |
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G |
RT1-Bb |
RT1 class II, locus Bb |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-BB mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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G |
RT1-CE11 |
RT1 class I, locus CE11 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-CE11 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362
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G |
RT1-CE14 |
RT1 class I, locus CE14 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE14 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134
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G |
RT1-CE15 |
RT1 class I, locus CE15 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-CE15 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563 Ensembl chr20:3,264,172...3,279,563
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G |
RT1-CE16 |
RT1 class I, locus CE16 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE16 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
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G |
RT1-CE2 |
RT1 class I, locus CE2 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
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G |
RT1-CE3 |
RT1 class I, locus CE3 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE3 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
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G |
RT1-CE4 |
RT1 class I, locus CE4 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE4 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,431,509...3,504,535
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G |
RT1-CE5 |
RT1 class I, locus CE5 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE5 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,403,418...3,479,476
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G |
RT1-N1 |
RT1 class Ib, locus N1 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-N1 mRNA |
CTD |
PMID:22760963 |
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G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
Corn Oil results in increased expression of S100A8 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
EXP |
Corn Oil results in increased expression of S100A9 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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G |
Scd |
stearoyl-CoA desaturase |
affects expression |
EXP |
Corn Oil affects the expression of SCD1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scn1b |
sodium voltage-gated channel beta subunit 1 |
affects expression |
EXP |
Corn Oil affects the expression of SCN1B mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
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G |
Sds |
serine dehydratase |
affects expression |
EXP |
Corn Oil affects the expression of SDS mRNA |
CTD |
PMID:16360708 |
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NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Corn Oil results in decreased expression of SFRP2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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G |
Slc25a20 |
solute carrier family 25 member 20 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a25 |
solute carrier family 25 member 25 |
affects expression |
EXP |
Corn Oil affects the expression of SLC25A25 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
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G |
Sod1 |
superoxide dismutase 1 |
decreases activity multiple interactions |
ISO |
Corn Oil results in decreased activity of SOD1 protein [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein] |
CTD |
PMID:17194920 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sparc |
secreted protein acidic and cysteine rich |
increases expression |
EXP |
Corn Oil results in increased expression of SPARC mRNA |
CTD |
PMID:22760963 |
|
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Sqle |
squalene epoxidase |
affects expression |
EXP |
Corn Oil affects the expression of SQLE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
affects expression |
EXP |
Corn Oil affects the expression of SREBF1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Sstr3 |
somatostatin receptor 3 |
decreases expression |
EXP |
Corn Oil results in decreased expression of SSTR3 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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G |
Sugt1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
increases expression |
ISO |
Corn Oil results in increased expression of SUGT1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
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G |
Syk |
spleen associated tyrosine kinase |
increases expression |
ISO |
Corn Oil results in increased expression of SYK mRNA |
CTD |
PMID:23409006 |
|
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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G |
Tac1 |
tachykinin, precursor 1 |
decreases expression |
EXP |
Corn Oil results in decreased expression of TAC1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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G |
Tat |
tyrosine aminotransferase |
affects expression |
EXP |
Corn Oil affects the expression of TAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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G |
Tbc1d14 |
TBC1 domain family, member 14 |
affects expression |
EXP |
Corn Oil affects the expression of TBC1D14 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:74,172,652...74,272,182
Ensembl chr14:74,172,664...74,272,183
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G |
Tgfa |
transforming growth factor alpha |
decreases expression |
EXP |
Corn Oil results in decreased expression of TGFA mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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G |
Ticam1 |
TIR domain containing adaptor molecule 1 |
increases expression |
ISO |
Corn Oil results in increased expression of TICAM1 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
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G |
Tjp2 |
tight junction protein 2 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP2 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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G |
Tjp3 |
tight junction protein 3 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP3 mRNA |
CTD |
PMID:33263755 |
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NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
increases expression |
ISO |
Corn Oil results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:33263755 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tollip |
toll interacting protein |
increases expression |
ISO |
Corn Oil results in increased expression of TOLLIP mRNA |
CTD |
PMID:33263755 |
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NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625
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G |
Tpcn2 |
two pore segment channel 2 |
affects expression |
EXP |
Corn Oil affects the expression of TPCN2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
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G |
Tpt1 |
tumor protein, translationally-controlled 1 |
increases expression |
EXP |
Corn Oil results in increased expression of TPT1 mRNA |
CTD |
PMID:22760963 |
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NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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G |
Vegfb |
vascular endothelial growth factor B |
decreases expression |
EXP |
Corn Oil results in decreased expression of VEGFB mRNA |
CTD |
PMID:22760963 |
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NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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G |
Vnn1 |
vanin 1 |
affects expression |
EXP |
Corn Oil affects the expression of VNN1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xiap |
X-linked inhibitor of apoptosis |
decreases expression |
ISO |
Corn Oil results in decreased expression of XIAP mRNA |
CTD |
PMID:33263755 |
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NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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G |
Xpnpep2 |
X-prolyl aminopeptidase 2 |
affects expression |
EXP |
Corn Oil affects the expression of XPNPEP2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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G |
Zdhhc23 |
zinc finger DHHC-type palmitoyltransferase 23 |
affects expression |
EXP |
Corn Oil affects the expression of ZDHHC23 mRNA |
CTD |
PMID:16360708 |
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NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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G |
Aars1 |
alanyl-tRNA synthetase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of AARS1 mRNA |
CTD |
PMID:24690739 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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G |
Abat |
4-aminobutyrate aminotransferase |
multiple interactions |
EXP |
[Ethanol co-treated with Disulfiram] results in decreased activity of ABAT protein; [Ethanol co-treated with Disulfiram] results in decreased expression of ABAT mRNA |
CTD |
PMID:9591243 |
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NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ABCA1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abca3 |
ATP binding cassette subfamily A member 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ABCA3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity multiple interactions |
ISO |
Disulfiram results in decreased activity of ABCB11 protein Disulfiram inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] |
CTD |
PMID:24014644 |
|
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions decreases activity |
ISO |
Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein] Disulfiram metabolite results in decreased activity of ABCB1 protein; Disulfiram results in decreased activity of ABCB1 protein |
CTD |
PMID:10841824 PMID:14978246 PMID:16028354 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
decreases activity multiple interactions |
ISO |
Disulfiram results in decreased activity of ABCC1 protein Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC1 protein] |
CTD |
PMID:14978246 |
|
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC4 protein]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] |
CTD |
PMID:14978246 |
|
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ABCG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acad11 |
acyl-CoA dehydrogenase family, member 11 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ACAD11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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G |
Ace2 |
angiotensin converting enzyme 2 |
decreases expression |
ISO |
Disulfiram results in decreased expression of ACE2 mRNA |
CTD |
PMID:32808185 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Ache |
acetylcholinesterase |
decreases expression |
EXP |
Disulfiram results in decreased expression of ACHE protein |
CTD |
PMID:3868355 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ACSS2 mRNA |
CTD |
PMID:24690739 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ACTA2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Adam9 |
ADAM metallopeptidase domain 9 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ADAM9 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ADAMTS1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adarb1 |
adenosine deaminase, RNA-specific, B1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ADARB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
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G |
Adcy3 |
adenylate cyclase 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ADCY3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
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G |
Adgre5 |
adhesion G protein-coupled receptor E5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ADGRE5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
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G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
decreases activity |
EXP |
Disulfiram results in decreased activity of ADH1 protein |
CTD |
PMID:15551062 |
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NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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G |
Adm |
adrenomedullin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ADM mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Afap1 |
actin filament associated protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of AFAP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263
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G |
Agxt |
alanine--glyoxylate aminotransferase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of AGXT mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
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G |
Agxt2 |
alanine-glyoxylate aminotransferase 2 |
multiple interactions |
EXP |
[Ethanol co-treated with Disulfiram] results in decreased activity of AGXT2 protein |
CTD |
PMID:9591243 |
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NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
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G |
Ahsa1 |
activator of Hsp90 ATPase activity 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of AHSA1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
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G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
increases expression |
ISO |
Disulfiram results in increased expression of AKR1B1 mRNA |
CTD |
PMID:20566472 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
increases expression |
ISO |
Disulfiram results in increased expression of AKR1B10 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
Disulfiram results in increased expression of AKR1C1 mRNA |
CTD |
PMID:20566472 |
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NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression |
ISO |
Disulfiram results in increased expression of AKR1C3 mRNA |
CTD |
PMID:20566472 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
ISO |
Disulfiram results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:34182011 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alad |
aminolevulinate dehydratase |
multiple interactions |
EXP |
[Disulfiram co-treated with Lead] results in decreased activity of ALAD protein |
CTD |
PMID:2748540 |
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NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases activity decreases expression multiple interactions |
EXP ISO |
Disulfiram results in decreased activity of ALDH1A1 protein Disulfiram results in decreased expression of ALDH1A1 mRNA; Disulfiram results in decreased expression of ALDH1A1 protein Disulfiram inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to maphosphamide] |
CTD |
PMID:8562935 PMID:10998257 PMID:21035945 PMID:34242567 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
decreases activity |
ISO |
Disulfiram results in decreased activity of ALDH1A2 protein |
CTD |
PMID:22079344 |
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NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
decreases activity decreases expression multiple interactions |
ISO EXP |
Disulfiram metabolite results in decreased activity of ALDH2 protein; Disulfiram results in decreased activity of ALDH2 protein Disulfiram results in decreased expression of ALDH2 mRNA [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde |
CTD |
PMID:9585485 PMID:10513990 PMID:11142365 PMID:21334317 PMID:21376711 PMID:22079344 PMID:24496638 More...
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Aldh3a1 |
aldehyde dehydrogenase 3 family, member A1 |
increases metabolic processing |
ISO |
ALDH3A1 protein results in increased metabolism of Disulfiram |
CTD |
PMID:18591790 |
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NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Ano6 |
anoctamin 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ANO6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
increases expression |
ISO |
Disulfiram results in increased expression of APAF1 mRNA |
CTD |
PMID:34182011 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apbb3 |
amyloid beta precursor protein binding family B member 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of APBB3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
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G |
Apcdd1l |
APC down-regulated 1 like |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of APCDD1L mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:162,587,484...162,658,362
Ensembl chr 3:162,582,252...162,658,073
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of APP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
[Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein; Disulfiram inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] |
CTD |
PMID:19789329 PMID:33049310 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arc |
activity-regulated cytoskeleton-associated protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ARC mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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G |
Asgr1 |
asialoglycoprotein receptor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ASGR1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
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G |
Asmtl |
acetylserotonin O-methyltransferase-like |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ASMTL mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:16,315,335...16,318,083
Ensembl chr12:16,315,414...16,318,080
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ASNS mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Atf1 |
activating transcription factor 1 |
multiple interactions |
ISO |
[Disulfiram co-treated with Copper] results in decreased activity of ATF1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF1 protein] |
CTD |
PMID:15367699 |
|
NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions |
ISO |
[Disulfiram co-treated with Copper] results in decreased activity of ATF2 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF2 protein] |
CTD |
PMID:15367699 |
|
NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ATF3 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA] |
CTD |
PMID:24690739 PMID:32661532 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atg101 |
autophagy related 101 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ATG101 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633
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G |
Atp2b1 |
ATPase plasma membrane Ca2+ transporting 1 |
decreases expression |
EXP |
Disulfiram results in decreased expression of ATP2B1 mRNA |
CTD |
PMID:15003327 |
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NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
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G |
Atp5mk |
ATP synthase membrane subunit K |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ATP5MK mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761 Ensembl chr10:245,973,914...245,980,761
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G |
Atp6v0d1 |
ATPase H+ transporting V0 subunit D1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ATP6V0D1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
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G |
Atp6v1g1 |
ATPase H+ transporting V1 subunit G1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ATP6V1G1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
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G |
Atxn1l |
ataxin 1 like |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ATXN1L mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:37,700,341...37,711,529
Ensembl chr19:37,700,106...37,711,538
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G |
Atxn3 |
ataxin 3 |
affects localization increases response to substance |
ISO |
Disulfiram affects the localization of ATXN3 protein alternative form ATXN3 protein alternative form results in increased susceptibility to Disulfiram |
CTD |
PMID:31378764 |
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NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
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G |
Bad |
BCL2-associated agonist of cell death |
increases expression |
ISO |
Disulfiram results in increased expression of BAD mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag3 |
BAG cochaperone 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of BAG3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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|
G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO |
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein |
CTD |
PMID:24126434 |
|
NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO |
Disulfiram results in increased expression of BAX mRNA; Disulfiram results in increased expression of BAX protein [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Copper co-treated with Disulfiram] results in increased expression of BAX protein |
CTD |
PMID:17079463 PMID:23033007 PMID:24126434 PMID:34182011 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
Disulfiram results in increased expression of BBC3 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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|
G |
Bbs2 |
Bardet-Biedl syndrome 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of BBS2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993
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|
G |
Bccip |
BRCA2 and CDKN1A interacting protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of BCCIP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958
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|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO |
[Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Copper co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein Disulfiram results in decreased expression of BCL2 mRNA |
CTD |
PMID:21911303 PMID:23033007 PMID:24126434 PMID:34182011 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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|
G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
Disulfiram results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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|
G |
Bcl2l11 |
Bcl2-like 11 |
increases expression |
ISO |
Disulfiram results in increased expression of BCL2L11 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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|
G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of BDNF mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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|
G |
Becn1 |
beclin 1 |
increases expression |
ISO |
Disulfiram results in increased expression of BECN1 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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|
G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
EXP |
Disulfiram results in increased expression of BGLAP mRNA |
CTD |
PMID:24496638 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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|
G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Disulfiram results in increased expression of BIRC5 protein |
CTD |
PMID:34182011 |
|
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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|
G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA] |
CTD |
PMID:22285649 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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|
G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression |
ISO |
Disulfiram results in increased expression of BNIP3 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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|
G |
Brf2 |
BRF2, RNA polymerase III transcription initiation factor subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of BRF2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059
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|
G |
Btk |
Bruton tyrosine kinase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of BTK mRNA |
CTD |
PMID:24690739 |
|
NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853
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|
G |
C11h3orf52 |
similar to human chromosome 3 open reading frame 52 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of C3ORF52 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:55,166,986...55,192,273
Ensembl chr11:55,166,678...55,192,292
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|
G |
C1r |
complement C1r |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of C1R mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
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|
G |
C1s |
complement C1s |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of C1S mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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|
G |
C3h11orf96 |
similar to human chromosome 11 open reading frame 96 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of C11ORF96 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
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|
G |
C4h2orf42 |
similar to human chromosome 2 open reading frame 42 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of C2ORF42 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:118,887,688...118,916,808
Ensembl chr 4:118,888,112...118,916,936
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|
G |
C9h2orf49 |
similar to human chromosome 2 open reading frame 49 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of C2ORF49 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:45,371,396...45,382,123
Ensembl chr 9:45,371,430...45,382,120
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|
G |
Cacybp |
calcyclin binding protein |
multiple interactions increases expression |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CACYBP mRNA Disulfiram results in increased expression of CACYBP mRNA; Disulfiram results in increased expression of CACYBP protein |
CTD |
PMID:24690739 PMID:34182011 |
|
NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
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|
G |
Calcb |
calcitonin-related polypeptide, beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CALCB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125
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|
G |
Cald1 |
caldesmon 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CALD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
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|
G |
Calm1 |
calmodulin 1 |
decreases expression |
ISO |
Disulfiram results in decreased expression of CALM1 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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|
G |
Calm2 |
calmodulin 2 |
increases expression |
ISO |
Disulfiram results in increased expression of CALM2 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287 Ensembl chr15:7,091,567...7,104,287
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|
G |
Calm3 |
calmodulin 3 |
decreases expression |
ISO |
Disulfiram results in decreased expression of CALM3 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
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|
G |
Car2 |
carbonic anhydrase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CA2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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|
G |
Car7 |
carbonic anhydrase 7 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CA7 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
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|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity |
EXP ISO |
[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein] [Disulfiram binds to Copper] which results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein] Disulfiram results in increased activity of CASP3 protein |
CTD |
PMID:11239917 PMID:17026967 PMID:17079463 PMID:24193513 PMID:24690739 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Casp7 |
caspase 7 |
increases activity |
ISO |
Disulfiram results in increased activity of CASP7 protein |
CTD |
PMID:17026967 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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|
G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO |
[Disulfiram binds to Copper] which results in increased activity of CASP9 protein Disulfiram results in increased expression of CASP9 mRNA |
CTD |
PMID:24690739 PMID:34182011 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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|
G |
Cat |
catalase |
increases expression multiple interactions decreases expression |
ISO |
Disulfiram results in increased expression of CAT mRNA Zinc Sulfate inhibits the reaction [Disulfiram results in decreased expression of CAT mRNA] |
CTD |
PMID:20566472 PMID:32712770 PMID:34182011 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Ccar1 |
cell division cycle and apoptosis regulator 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CCAR1 protein |
CTD |
PMID:24690739 |
|
NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
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|
G |
Ccdc59 |
coiled-coil domain containing 59 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CCDC59 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:41,142,760...41,149,143
Ensembl chr 7:41,142,760...41,149,143
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|
G |
Ccdc92 |
coiled-coil domain containing 92 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CCDC92 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:31,796,102...31,823,333
Ensembl chr12:31,796,684...31,823,337
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|
G |
Cck |
cholecystokinin |
decreases expression multiple interactions |
EXP ISO |
Disulfiram results in decreased expression of CCK protein alternative form [Disulfiram binds to Copper] which results in decreased expression of CCK mRNA |
CTD |
PMID:8246921 PMID:24690739 |
|
NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
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|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases secretion |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CCL2 mRNA; [Zinc Sulfate co-treated with Disulfiram] inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] Disulfiram results in decreased secretion of CCL2 protein |
CTD |
PMID:24690739 PMID:32712770 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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|
G |
Ccl26 |
C-C motif chemokine ligand 26 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CCL26 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
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|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] [Disulfiram binds to Copper] which results in increased expression of CCL5 mRNA |
CTD |
PMID:19016906 PMID:24690739 |
|
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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|
G |
Ccna2 |
cyclin A2 |
multiple interactions decreases expression |
ISO |
[Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein Disulfiram results in decreased expression of CCNA2 mRNA |
CTD |
PMID:15367699 PMID:34182011 |
|
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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|
G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Disulfiram results in decreased expression of CCND1 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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|
G |
Ccnd2 |
cyclin D2 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA] |
CTD |
PMID:22285649 |
|
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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|
G |
Ccnk |
cyclin K |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CCNK mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
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|
G |
Ccpg1 |
cell cycle progression 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CCPG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
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|
G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Disulfiram results in increased expression of CCR2 protein |
CTD |
PMID:32712770 |
|
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
|
|
G |
Ccr5 |
C-C motif chemokine receptor 5 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] |
CTD |
PMID:19016906 |
|
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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|
G |
Cd163 |
CD163 molecule |
multiple interactions decreases expression |
ISO |
[Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD163 mRNA Disulfiram results in decreased expression of CD163 mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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|
G |
Cd36 |
CD36 molecule |
multiple interactions decreases expression |
ISO |
[Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD36 mRNA Disulfiram results in decreased expression of CD36 mRNA |
CTD |
PMID:32712770 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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|
G |
Cd46 |
CD46 molecule |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CD46 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
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G |
Cd47 |
Cd47 molecule |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CD47 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
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|
G |
Cd9 |
CD9 molecule |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CD9 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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|
G |
Cdc42ep5 |
CDC42 effector protein 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CDC42EP5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:70,035,921...70,038,990
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|
G |
Cdh11 |
cadherin 11 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CDH11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
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|
G |
Cdh2 |
cadherin 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CDH2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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|
G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression |
ISO |
Disulfiram results in decreased expression of CDK2 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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|
G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
Disulfiram results in decreased expression of CDK4 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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|
G |
Cdk5r1 |
cyclin-dependent kinase 5 regulatory subunit 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CDK5R1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
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|
G |
Cdk5rap3 |
CDK5 regulatory subunit associated protein 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CDK5RAP3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
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|
G |
Cdk6 |
cyclin-dependent kinase 6 |
decreases expression |
ISO |
Disulfiram results in decreased expression of CDK6 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Disulfiram results in increased expression of CDKN1A mRNA |
CTD |
PMID:34182011 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
|
|
G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression multiple interactions |
ISO |
Disulfiram results in increased expression of CDKN1B mRNA; Disulfiram results in increased expression of CDKN1B protein [Disulfiram binds to Copper] which results in increased expression of CDKN1B protein |
CTD |
PMID:17079463 PMID:24690739 PMID:34182011 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
|
|
G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CDKN1C mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
|
|
G |
Cdkn2aip |
CDKN2A interacting protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
increases expression |
ISO |
Disulfiram results in increased expression of CDKN2B mRNA |
CTD |
PMID:34182011 |
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NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cemip |
cell migration inducing hyaluronidase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CEMIP mRNA |
CTD |
PMID:24690739 |
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NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
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G |
Cenpw |
centromere protein W |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CENPW mRNA |
CTD |
PMID:24690739 |
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NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
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G |
Cfap53 |
cilia and flagella associated protein 53 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CFAP53 mRNA |
CTD |
PMID:24690739 |
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NCBI chr18:67,884,651...67,955,873
Ensembl chr18:67,869,855...67,952,318
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G |
Cfb |
complement factor B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CFB mRNA |
CTD |
PMID:24690739 |
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NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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G |
Cfl1 |
cofilin 1 |
increases expression |
ISO |
Disulfiram results in increased expression of CFL1 protein |
CTD |
PMID:34182011 |
|
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Chga |
chromogranin A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CHGA mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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G |
Chmp1b |
charged multivesicular body protein 1B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CHMP1B mRNA |
CTD |
PMID:24690739 |
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NCBI chr18:60,740,349...60,742,879
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G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CHORDC1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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G |
Cilp |
cartilage intermediate layer protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CILP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
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G |
Cirbp |
cold inducible RNA binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CIRBP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
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G |
Ckap4 |
cytoskeleton-associated protein 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CKAP4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914
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G |
Cldn1 |
claudin 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CLDN1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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G |
Clec7a |
C-type lectin domain containing 7A |
increases expression |
ISO |
Disulfiram results in increased expression of CLEC7A protein |
CTD |
PMID:32712770 |
|
NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
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G |
Clp1 |
cleavage factor polyribonucleotide kinase subunit 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CLP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421
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G |
Clta |
clathrin, light chain A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CLTA mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Cmklr2 |
chemerin chemokine-like receptor 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CMKLR2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:64,583,310...64,617,883
Ensembl chr 9:64,585,594...64,586,655
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G |
Cntnap1 |
contactin associated protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
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G |
Col12a1 |
collagen type XII alpha 1 chain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of COL12A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
Disulfiram results in decreased expression of COL1A1 protein |
CTD |
PMID:34182011 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of COL1A2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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|
G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col4a1 |
collagen type IV alpha 1 chain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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G |
Col5a1 |
collagen type V alpha 1 chain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of COL5A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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G |
Commd9 |
COMM domain containing 9 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of COMMD9 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:88,175,909...88,190,427
Ensembl chr 3:88,175,987...88,190,439
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G |
Crabp2 |
cellular retinoic acid binding protein 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
[Disulfiram co-treated with Copper] results in decreased activity of CREB1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of CREB1 protein] |
CTD |
PMID:15367699 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Creld2 |
cysteine-rich with EGF-like domains 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CRELD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
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G |
Crim1 |
cysteine rich transmembrane BMP regulator 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CRIM1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
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G |
Cript |
CXXC repeat containing interactor of PDZ3 domain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CRIPT mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399
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G |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CRISPLD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
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G |
Cryab |
crystallin, alpha B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CRYAB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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G |
Cse1l |
chromosome segregation 1 like |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
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G |
Csnk1e |
casein kinase 1, epsilon |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CSNK1E mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
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G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of AXUD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
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G |
Csrp2 |
cysteine and glycine-rich protein 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CSRP2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
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G |
Cst6 |
cystatin E/M |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CST6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
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G |
Cth |
cystathionine gamma-lyase |
increases expression |
ISO |
Disulfiram results in increased expression of CTH protein |
CTD |
PMID:34242567 |
|
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Cwc25 |
CWC25 spliceosome-associated protein homolog |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CWC25 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of CXCR4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] |
CTD |
PMID:22285649 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA] |
CTD |
PMID:22285649 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases activity |
ISO |
Disulfiram results in decreased activity of CYP1A1 protein |
CTD |
PMID:33814510 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity |
ISO |
Disulfiram results in decreased activity of CYP1B1 protein |
CTD |
PMID:33814510 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions increases expression |
EXP |
GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA] |
CTD |
PMID:8390837 |
|
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
increases expression multiple interactions |
EXP |
Disulfiram results in increased expression of CYP2B2 mRNA GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] |
CTD |
PMID:8390837 |
|
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
decreases activity decreases expression |
EXP |
Disulfiram results in decreased activity of CYP2C11 protein Disulfiram results in decreased expression of CYP2C11 protein |
CTD |
PMID:9393675 |
|
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions decreases activity decreases expression |
ISO EXP |
[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene; Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane] Disulfiram results in decreased expression of CYP2E1 mRNA; Disulfiram results in decreased expression of CYP2E1 protein Disulfiram binds to and results in decreased activity of CYP2E1 protein |
CTD |
PMID:1664256 PMID:8637342 PMID:9393675 PMID:10805064 PMID:18754103 PMID:20470765 PMID:21915887 PMID:23669205 More...
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2r1 |
cytochrome P450, family 2, subfamily r, polypeptide 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CYP2R1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases expression increases response to substance decreases activity |
EXP ISO |
Disulfiram results in decreased expression of CYP3A2 mRNA CYP3A4 protein results in increased susceptibility to Disulfiram Disulfiram results in decreased activity of CYP3A2 protein |
CTD |
PMID:9393675 PMID:21540358 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Dag1 |
dystroglycan 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of DAG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
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G |
Dbh |
dopamine beta-hydroxylase |
decreases activity affects response to substance |
ISO |
Disulfiram results in decreased activity of DBH protein DBH gene SNP affects the susceptibility to Disulfiram DBH gene polymorphism affects the susceptibility to Disulfiram |
CTD |
PMID:90468 PMID:16163519 PMID:19462300 |
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NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
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G |
Dcaf13 |
DDB1 and CUL4 associated factor 13 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DCAF13 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142
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G |
Dcxr |
dicarbonyl and L-xylulose reductase |
multiple interactions |
ISO |
[Disulfiram co-treated with NADP] binds to DCXR protein |
CTD |
PMID:25526675 |
|
NCBI chr10:106,006,404...106,008,293
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DDIT3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddx39a |
DExD-box helicase 39A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DDX39A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
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G |
Ddx60 |
DEXD/H-box helicase 60 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of DDX60 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526
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G |
Dedd2 |
death effector domain containing 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DEDD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714
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G |
Dhdh |
dihydrodiol dehydrogenase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DHDH mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197
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G |
Dhrs2 |
dehydrogenase/reductase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DHRS2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
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G |
Dhrs3 |
dehydrogenase/reductase 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of DHRS3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
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G |
Dkk3 |
dickkopf WNT signaling pathway inhibitor 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of DKK3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
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G |
Dll1 |
delta like canonical Notch ligand 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DLL1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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G |
Dnaja4 |
DnaJ heat shock protein family (Hsp40) member A4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DNAJA4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DNAJB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajb6 |
DnaJ heat shock protein family (Hsp40) member B6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DNAJB6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dph3 |
diphthamide biosynthesis 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DPH3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265
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G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of DRAM1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
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G |
Dse |
dermatan sulfate epimerase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of DSE mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
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G |
Dusp2 |
dual specificity phosphatase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DUSP2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DUSP5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dynll2 |
dynein light chain LC8-type 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of DYNLL2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805
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G |
Eaf1 |
ELL associated factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of EAF1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:6,698,322...6,713,071
Ensembl chr16:6,698,322...6,713,071
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G |
Edil3 |
EGF like repeats and discoidin domains 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of EDIL3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008
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G |
Eed |
embryonic ectoderm development |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of EED mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of EFEMP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of EGR1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Eif4a3 |
eukaryotic translation initiation factor 4A3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of EIF4A3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
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G |
Ell2 |
elongation factor for RNA polymerase II 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ELL2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
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G |
Elof1 |
elongation factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ELOF1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:20,645,336...20,650,888
Ensembl chr 8:20,645,336...20,650,579
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Disulfiram binds to and results in decreased activity of ESR1 protein |
CTD |
PMID:33049310 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ETS1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
F12 |
coagulation factor XII |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of F12 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
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G |
Fam210a |
family with sequence similarity 210, member A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FAM210A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
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G |
Fam234a |
family with sequence similarity 234, member A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of FAM234A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:15,232,267...15,263,529
Ensembl chr10:15,232,278...15,263,488
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G |
Fam32a |
family with sequence similarity 32, member A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FAM32A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:17,603,054...17,607,376
Ensembl chr16:17,603,946...17,607,398
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G |
Faslg |
Fas ligand |
increases expression |
ISO |
Disulfiram results in increased expression of FASLG mRNA |
CTD |
PMID:34182011 |
|
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fech |
ferrochelatase |
increases expression |
ISO |
Disulfiram results in increased expression of FECH mRNA |
CTD |
PMID:20566472 |
|
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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G |
Fkbp1a |
FKBP prolyl isomerase 1A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FKBP1A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
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G |
Flcn |
folliculin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FLCN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
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G |
Fndc11 |
fibronectin type III domain containing 11 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FNDC11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:168,330,607...168,333,111
Ensembl chr 3:168,330,602...168,334,617
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FOS mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FOSB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Foxa3 |
forkhead box A3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FOXA3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
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G |
Foxj1 |
forkhead box J1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FOXJ1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237
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G |
Foxo1 |
forkhead box O1 |
increases expression |
ISO |
Disulfiram results in increased expression of FOXO1 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxo3 |
forkhead box O3 |
increases expression |
ISO |
Disulfiram results in increased expression of FOXO3 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Foxo4 |
forkhead box O4 |
increases expression |
ISO |
Disulfiram results in increased expression of FOXO4 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115
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G |
Frg1 |
FSHD region gene 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FRG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:50,925,783...50,946,661
Ensembl chr16:50,925,803...50,946,661
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] |
CTD |
PMID:22285649 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fshr |
follicle stimulating hormone receptor |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA] |
CTD |
PMID:22285649 |
|
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Fstl1 |
follistatin-like 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of FSTL1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
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G |
Ftcd |
formimidoyltransferase cyclodeaminase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of FTCD mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
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G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
Disulfiram results in increased expression of FTL mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases expression |
ISO |
Disulfiram results in increased expression of G6PD mRNA |
CTD |
PMID:20566472 |
|
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Disulfiram results in increased expression of GADD45A mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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G |
Galnt10 |
polypeptide N-acetylgalactosaminyltransferase 10 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GALNT10 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013
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G |
Gas6 |
growth arrest specific 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GAS6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gata2 |
GATA binding protein 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GATA2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Gbp4 |
guanylate binding protein 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GBP4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
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G |
Gcc1 |
GRIP and coiled-coil domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GCC1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663
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G |
Gcgr |
glucagon receptor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GCGR mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Disulfiram results in increased expression of GCLC mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
Disulfiram results in increased expression of GCLM mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gem |
GTP binding protein overexpressed in skeletal muscle |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GEM mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
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G |
Gemin6 |
gem (nuclear organelle) associated protein 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GEMIN6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612
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G |
Gh1 |
growth hormone 1 |
multiple interactions |
EXP |
GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA]; GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] |
CTD |
PMID:8390837 |
|
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
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G |
Glg1 |
golgi glycoprotein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
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G |
Glrx2 |
glutaredoxin 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GLRX2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
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|
G |
Gosr2 |
golgi SNAP receptor complex member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GOSR2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625
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|
G |
Gpsm1 |
G-protein signaling modulator 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GPSM1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827
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G |
Gpt2 |
glutamic--pyruvic transaminase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GPT2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
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|
G |
Gpx3 |
glutathione peroxidase 3 |
increases expression |
ISO |
Disulfiram results in increased expression of GPX3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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|
G |
Gramd1a |
GRAM domain containing 1A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GRAMD1A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336
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|
G |
Gramd2b |
GRAM domain containing 2B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GRAMD2B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953
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|
G |
Grwd1 |
glutamate-rich WD repeat containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GRWD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
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|
G |
Gsdmd |
gasdermin D |
decreases cleavage multiple interactions |
ISO |
Disulfiram results in decreased cleavage of GSDMD protein Disulfiram binds to and results in decreased activity of GSDMD protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein] |
CTD |
PMID:32367036 PMID:33851234 |
|
NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055
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|
G |
Gsdme |
gasdermin E |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of GSDME mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
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|
G |
Gsr |
glutathione-disulfide reductase |
increases expression |
ISO |
Disulfiram results in increased expression of GSR mRNA |
CTD |
PMID:20566472 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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|
G |
Gtf2b |
general transcription factor IIB |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of GTF2B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
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|
G |
H2ac20 |
H2A clustered histone 20 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of H2AC20 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:183,779,879...183,780,357
|
|
G |
H2ax |
H2A.X variant histone |
multiple interactions increases expression |
ISO |
Disulfiram inhibits the reaction [captax results in increased expression of H2AX protein]; Disulfiram inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Disulfiram inhibits the reaction [Trichloroethylene results in increased phosphorylation of H2AX protein] Disulfiram results in increased expression of H2AX protein |
CTD |
PMID:28300663 PMID:29722447 PMID:34830855 PMID:35279910 |
|
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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|
G |
H2bc12 |
H2B clustered histone 12 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of H2BC12 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:42,485,699...42,486,162
|
|
G |
H2bc8 |
H2B clustered histone 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of H2BC8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:42,708,658...42,709,408
|
|
G |
H3f4 |
H3.4 histone, cluster member |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of H3-4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:43,740,702...43,741,262
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G |
H6pd |
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of H6PD mRNA |
CTD |
PMID:24690739 |
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NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
multiple interactions increases expression |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HBA1 mRNA Disulfiram results in increased expression of HBA1 protein |
CTD |
PMID:24690739 PMID:34182011 |
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NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HBEGF mRNA |
CTD |
PMID:24690739 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hes1 |
hes family bHLH transcription factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HES1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hes6 |
hes family bHLH transcription factor 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HES6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
Disulfiram results in increased expression of HMOX1 mRNA [Disulfiram binds to Copper] which results in decreased expression of HMOX1 mRNA; [Disulfiram co-treated with Zinc Sulfate] results in increased expression of HMOX1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA] |
CTD |
PMID:20566472 PMID:24690739 PMID:32661532 PMID:32712770 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of HNRNPA2B1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hoxa1 |
homeobox A1 |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] |
CTD |
PMID:23696197 |
|
NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hoxd1 |
homeo box D1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HOXD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769
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G |
Hrk |
harakiri, BCL2 interacting protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HRK mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:38,387,484...38,409,652
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G |
Hs3st2 |
heparan sulfate-glucosamine 3-sulfotransferase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HS3ST2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
multiple interactions |
ISO |
[Disulfiram co-treated with NAD] binds to HSD11B1 protein |
CTD |
PMID:25526675 |
|
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity |
ISO |
Disulfiram results in decreased activity of HSD11B2 protein |
CTD |
PMID:22796344 |
|
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSP90AA1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPA1A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
increases expression multiple interactions |
ISO |
Disulfiram results in increased expression of HSPA1B mRNA [Disulfiram binds to Copper] which results in decreased expression of HSPA1B mRNA |
CTD |
PMID:20566472 PMID:24690739 |
|
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPA1L mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
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G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPA4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
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G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPA6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:83,273,176...83,274,317
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|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPA8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspb8 |
heat shock protein family B (small) member 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPB8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of HSPH1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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G |
Htr2b |
5-hydroxytryptamine receptor 2B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
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G |
Id2 |
inhibitor of DNA binding 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ID2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Ier5 |
immediate early response 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of IER5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IFIT2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IFNGR2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
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G |
Igf2r |
insulin-like growth factor 2 receptor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IGF2R mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
multiple interactions increases expression |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA; [Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein [Disulfiram cotreated with copper(+2)] increases expression of IGFBP7 mRNA in malignant pleural mesothelioma cells |
CTD RGD |
PMID:24690739 PMID:24690739 |
RGD:401960877 |
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
[Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] |
CTD |
PMID:33579316 PMID:33851234 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IL1A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IL1B mRNA; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [Nigericin results in increased secretion of IL1B protein] Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:24690739 PMID:32367036 PMID:32712770 PMID:33579316 PMID:33851234 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of IL6 mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein] |
CTD |
PMID:24690739 PMID:32712770 PMID:33851234 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Insig1 |
insulin induced gene 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Irf8 |
interferon regulatory factor 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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G |
Isy1 |
ISY1 splicing factor homolog |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ISY1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188
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G |
Itga11 |
integrin subunit alpha 11 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ITGA11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407
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G |
Itga3 |
integrin subunit alpha 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ITGA3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
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G |
Itgam |
integrin subunit alpha M |
increases expression |
ISO |
Disulfiram results in increased expression of ITGAM protein |
CTD |
PMID:32712770 |
|
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgav |
integrin subunit alpha V |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ITGAV mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Itgb1 |
integrin subunit beta 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ITGB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb5 |
integrin subunit beta 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ITGB5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
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G |
Jag2 |
jagged canonical Notch ligand 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of JAG2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased expression of and results in increased phosphorylation of JUN protein; [Copper co-treated with Disulfiram] results in increased expression of and results in increased phosphorylation of JUN protein; [Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [[Disulfiram co-treated with Copper co-treated with Doxorubicin] results in increased phosphorylation of and results in increased expression of JUN protein] |
CTD |
PMID:21911303 PMID:23033007 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcng1 |
potassium voltage-gated channel modifier subfamily G member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of KCNG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
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G |
Khdrbs3 |
KH RNA binding domain containing, signal transduction associated 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of KHDRBS3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
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G |
Klf10 |
KLF transcription factor 10 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of KLF10 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Klhl22 |
kelch-like family member 22 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of KLHL22 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770
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G |
Klhl5 |
kelch-like family member 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of KLHL5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:43,144,254...43,206,192
Ensembl chr14:43,144,257...43,184,238
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G |
Krt1 |
keratin 1 |
increases expression |
ISO |
Disulfiram results in increased expression of KRT1 mRNA; Disulfiram results in increased expression of KRT1 protein |
CTD |
PMID:34182011 |
|
NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
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G |
Krt75 |
keratin 75 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of KRT75 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
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G |
Lamc1 |
laminin subunit gamma 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of LAMC1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lamtor3 |
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of LAMTOR3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607
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G |
Lemd2 |
LEM domain nuclear envelope protein 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of LEMD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:5,282,397...5,296,621
Ensembl chr20:5,282,397...5,296,626
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] |
CTD |
PMID:22285649 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions |
ISO |
Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] |
CTD |
PMID:22285649 |
|
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Limch1 |
LIM and calponin homology domains 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of LIMCH1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191
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|
G |
Lipt1 |
lipoyltransferase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of LIPT1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:40,107,938...40,118,268
Ensembl chr 9:40,098,615...40,113,565
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|
G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of LMCD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
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|
G |
Lmtk2 |
lemur tyrosine kinase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of LMTK2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:10,426,772...10,508,750
Ensembl chr12:10,426,777...10,508,750
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G |
Loricrin |
loricrin cornified envelope precursor protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of LORICRIN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807
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G |
Lratd2 |
LRAT domain containing 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of LRATD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189
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G |
Lrp8 |
LDL receptor related protein 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of LRP8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
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G |
Lsmem1 |
leucine-rich single-pass membrane protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of LSMEM1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:57,251,720...57,261,590
Ensembl chr 6:57,252,056...57,261,653
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G |
Ltb4r |
leukotriene B4 receptor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of LTB4R mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:29,263,199...29,265,716
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G |
Luc7l3 |
LUC7-like 3 pre-mRNA splicing factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of CROP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538
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G |
Macf1 |
microtubule-actin crosslinking factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MACF1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
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G |
Mad2l1bp |
MAD2L1 binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAD2L1BP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
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G |
Mafb |
MAF bZIP transcription factor B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAFB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
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G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Disulfiram results in increased expression of MAFF mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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G |
Mafg |
MAF bZIP transcription factor G |
increases expression |
ISO |
Disulfiram results in increased expression of MAFG mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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G |
Mafk |
MAF bZIP transcription factor K |
increases expression |
ISO |
Disulfiram results in increased expression of MAFK mRNA |
CTD |
PMID:20566472 |
|
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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G |
Magoh |
mago homolog, exon junction complex subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAGOH mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617
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G |
Man1b1 |
mannosidase, alpha, class 1B, member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MAN1B1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006
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G |
Maoa |
monoamine oxidase A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAOA mRNA |
CTD |
PMID:24690739 |
|
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases expression |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAP1LC3B mRNA Disulfiram results in increased expression of MAP1LC3B mRNA |
CTD |
PMID:24690739 PMID:34182011 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAP2K3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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G |
Map3k13 |
mitogen-activated protein kinase kinase kinase 13 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
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G |
Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MAP3K20 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
[Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased phosphorylation of MAPK1 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:23033007 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
[Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased phosphorylation of MAPK3 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:23033007 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
EXP ISO |
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein] [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:11239917 PMID:24690739 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:24690739 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mapre2 |
microtubule-associated protein, RP/EB family, member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MAPRE2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044
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G |
Mcm2 |
minichromosome maintenance complex component 2 |
multiple interactions decreases expression |
ISO |
cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] |
CTD |
PMID:19789329 |
|
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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G |
Mcm5 |
minichromosome maintenance complex component 5 |
multiple interactions decreases expression |
ISO |
cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] |
CTD |
PMID:19789329 |
|
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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G |
Me1 |
malic enzyme 1 |
increases expression |
ISO |
Disulfiram results in increased expression of ME1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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G |
Mfsd3 |
major facilitator superfamily domain containing 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:108,419,644...108,423,469
Ensembl chr 7:108,421,350...108,423,461
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions decreases activity increases degradation |
ISO EXP |
[Disulfiram binds to Copper] which results in decreased expression of and results in decreased activity of MGMT protein; [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein; bortezomib inhibits the reaction [Disulfiram results in increased degradation of MGMT protein]; Disulfiram inhibits the reaction [O(6)-benzylguanine binds to MGMT protein]; Disulfiram results in decreased expression of and results in decreased activity of MGMT protein Disulfiram results in decreased activity of MGMT protein |
CTD |
PMID:24193513 |
|
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression |
ISO |
Disulfiram results in increased expression of MGST1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
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G |
Midn |
midnolin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MIDN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
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G |
Mif |
macrophage migration inhibitory factor |
increases expression |
ISO |
Disulfiram results in increased expression of MIF protein |
CTD |
PMID:34182011 |
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NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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G |
Mix23 |
mitochondrial matrix import factor 23 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MIX23 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:64,660,711...64,681,000
Ensembl chr11:64,660,711...64,681,000
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G |
Mmp10 |
matrix metallopeptidase 10 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MMP10 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression |
ISO |
Disulfiram results in decreased expression of MMP2 |
CTD |
PMID:18047805 |
|
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MMP3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases expression |
ISO |
Disulfiram results in decreased expression of MMP9 |
CTD |
PMID:18047805 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mppe1 |
metallophosphoesterase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MPPE1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:60,763,418...60,781,553
Ensembl chr18:60,763,419...60,781,553
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G |
Mrpl10 |
mitochondrial ribosomal protein L10 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MRPL10 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:82,026,031...82,034,451
Ensembl chr10:82,026,031...82,034,443
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G |
Mrpl18 |
mitochondrial ribosomal protein L18 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MRPL18 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
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G |
Mrpl45 |
mitochondrial ribosomal protein L45 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MRPL45 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474
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G |
Mst1 |
macrophage stimulating 1 |
increases expression |
ISO |
Disulfiram results in increased expression of MST1 mRNA |
CTD |
PMID:34182011 |
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NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
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G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
affects activity affects expression |
EXP |
Disulfiram affects the activity of COX1 protein Disulfiram affects the expression of COX1 mRNA |
CTD |
PMID:17936468 |
|
NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MT1A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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G |
Mt2A |
metallothionein 2A |
increases expression multiple interactions |
ISO |
Disulfiram results in increased expression of MT2A mRNA cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] |
CTD |
PMID:19789329 PMID:32661532 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mt3 |
metallothionein 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MT3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
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G |
Mtf1 |
metal-regulatory transcription factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MTF1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT1M mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] |
CTD |
PMID:24690739 PMID:32661532 |
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NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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G |
Mx1 |
MX dynamin like GTPase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MX1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
Disulfiram results in decreased expression of MYC mRNA |
CTD |
PMID:34182011 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Mylip |
myosin regulatory light chain interacting protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of MYLIP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
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G |
Mylk |
myosin light chain kinase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of MYLK mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
Nat14 |
N-acetyltransferase 14 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NAT14 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:68,910,599...68,913,452
Ensembl chr 1:68,910,601...68,912,733
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G |
Nceh1 |
neutral cholesterol ester hydrolase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NCEH1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
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G |
Ncoa7 |
nuclear receptor coactivator 7 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NCOA7 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
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G |
Ncstn |
nicastrin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NCSTN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454
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G |
Nefh |
neurofilament heavy chain |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NEFH mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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G |
Nfe2l3 |
NFE2 like bZIP transcription factor 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NFE2L3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NFKB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
decreases degradation multiple interactions |
EXP ISO |
Disulfiram results in decreased degradation of NFKBIA protein [Disulfiram binds to Copper] which results in increased expression of NFKBIA protein |
CTD |
PMID:10418820 PMID:24690739 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NFKBIB protein |
CTD |
PMID:24690739 |
|
NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Ngdn |
neuroguidin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NGDN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:28,489,950...28,497,286
Ensembl chr15:28,490,040...28,519,654
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G |
Niban1 |
niban apoptosis regulator 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NIBAN1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
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G |
Nol12 |
nucleolar protein 12 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NOL12 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:110,493,294...110,498,908
Ensembl chr 7:110,493,246...110,498,907
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G |
Nos2 |
nitric oxide synthase 2 |
affects expression |
EXP |
Disulfiram affects the expression of NOS2 mRNA |
CTD |
PMID:17936468 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nosip |
nitric oxide synthase interacting protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NOSIP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650
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G |
Npepl1 |
aminopeptidase-like 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NPEPL1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:162,893,932...162,906,491
Ensembl chr 3:162,893,943...162,906,492
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G |
Nppb |
natriuretic peptide B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NPPB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Nptx2 |
neuronal pentraxin 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NPTX2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression increases activity |
ISO EXP |
Disulfiram results in increased expression of NQO1 mRNA Disulfiram results in increased activity of NQO1 protein |
CTD |
PMID:16045903 PMID:20566472 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
Disulfiram binds to and affects the activity of NR1I2 protein Disulfiram binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:33049310 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nrarp |
Notch-regulated ankyrin repeat protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NRARP mRNA |
CTD |
PMID:24690739 |
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NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133
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G |
Nras |
NRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NRAS mRNA |
CTD |
PMID:24690739 |
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NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
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G |
Nrp1 |
neuropilin 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NRP1 mRNA |
CTD |
PMID:24690739 |
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NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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G |
Nt5e |
5' nucleotidase, ecto |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of NT5E mRNA |
CTD |
PMID:24690739 |
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NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
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G |
Nubp1 |
NUBP iron-sulfur cluster assembly factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NUBP1 mRNA |
CTD |
PMID:24690739 |
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NCBI chr10:5,259,328...5,270,848
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G |
Nxf1 |
nuclear RNA export factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NXF1 mRNA |
CTD |
PMID:24690739 |
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NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636
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G |
Nxt2 |
nuclear transport factor 2-like export factor 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of NXT2 mRNA |
CTD |
PMID:24690739 |
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NCBI chr X:105,855,616...105,862,902
Ensembl chr X:105,855,608...105,862,899
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G |
Oasl |
2'-5'-oligoadenylate synthetase-like |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of OASL mRNA |
CTD |
PMID:24690739 |
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NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
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G |
Osmr |
oncostatin M receptor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of OSMR mRNA |
CTD |
PMID:24690739 |
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NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
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G |
P3h3 |
prolyl 3-hydroxylase 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of P3H3 mRNA |
CTD |
PMID:24690739 |
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NCBI chr 4:157,646,242...157,662,035
Ensembl chr 4:157,646,243...157,662,035
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G |
P3h4 |
prolyl 3-hydroxylase family member 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of P3H4 mRNA |
CTD |
PMID:24690739 |
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NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093
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G |
Pam |
peptidylglycine alpha-amidating monooxygenase |
increases activity |
EXP |
Disulfiram results in increased activity of PAM protein |
CTD |
PMID:8246921 PMID:10347250 |
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NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases cleavage |
ISO |
[Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein; [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein; [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein] Disulfiram results in increased cleavage of PARP1 protein |
CTD |
PMID:17079463 PMID:19789329 PMID:23033007 PMID:24193513 PMID:24690739 PMID:34182011 More...
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PCK2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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G |
Pcnx4 |
pecanex 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PCNX4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:91,125,063...91,170,423
Ensembl chr 6:91,125,063...91,170,439
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G |
Pde5a |
phosphodiesterase 5A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PDE5A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PDGFRB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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G |
Pdlim5 |
PDZ and LIM domain 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PDLIM5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
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G |
Pdpn |
podoplanin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PDPN protein [Disulfiram binds to Copper] which results in increased expression of and results in increased phosphorylation of and results in increased ubiquitination of PDPN protein |
CTD |
PMID:24690739 |
|
NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
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G |
Pdrg1 |
p53 and DNA damage regulated 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PDRG1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858 Ensembl chr 3:141,476,501...141,483,858
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G |
Pgd |
phosphogluconate dehydrogenase |
increases expression |
ISO |
Disulfiram results in increased expression of PGD mRNA |
CTD |
PMID:20566472 |
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NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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G |
Phlda2 |
pleckstrin homology-like domain, family A, member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PHLDA2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836
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G |
Phldb2 |
pleckstrin homology-like domain, family B, member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PHLDB2 mRNA |
CTD |
PMID:24690739 |
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NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467
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G |
Pigq |
phosphatidylinositol glycan anchor biosynthesis, class Q |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PIGQ mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:14,942,571...14,958,584
Ensembl chr10:14,942,577...14,958,584
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G |
Pik3ip1 |
phosphoinositide-3-kinase interacting protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PIK3IP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608
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G |
Pip4k2a |
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PIP4K2A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029
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G |
Plod2 |
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PLOD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
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G |
Plpbp |
pyridoxal phosphate binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PLPBP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886
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G |
Plscr4 |
phospholipid scramblase 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PLSCR4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049
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G |
Plxnb2 |
plexin B2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA |
CTD |
PMID:24690739 |
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NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Disulfiram results in increased expression of PMAIP1 mRNA |
CTD |
PMID:34182011 |
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NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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G |
Pnldc1 |
PARN like ribonuclease domain containing exonuclease 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PNLDC1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:47,843,224...47,861,675
Ensembl chr 1:47,843,224...47,861,674
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G |
Pnma2 |
PNMA family member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:41,111,942...41,119,649
Ensembl chr15:41,112,009...41,121,427
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G |
Polr2c |
RNA polymerase II subunit C |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of POLR2C mRNA |
CTD |
PMID:24690739 |
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NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945
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G |
Polr2m |
RNA polymerase II subunit M |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of POLR2M mRNA |
CTD |
PMID:24690739 |
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NCBI chr 8:72,131,992...72,139,423
Ensembl chr 8:72,131,530...72,243,036
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G |
Pomc |
proopiomelanocortin |
decreases expression |
EXP |
Disulfiram results in decreased expression of POMC protein alternative form |
CTD |
PMID:8246921 |
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NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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G |
Pop4 |
POP4 homolog, ribonuclease P/MRP subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of POP4 mRNA |
CTD |
PMID:24690739 |
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NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443
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G |
Postn |
periostin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of POSTN mRNA |
CTD |
PMID:24690739 |
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NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects expression multiple interactions |
ISO |
Disulfiram affects the expression of PPARG mRNA Disulfiram binds to and results in increased activity of PPARG protein |
CTD |
PMID:32712770 PMID:33049310 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppia |
peptidylprolyl isomerase A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PPIA mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Ppp1r3c |
protein phosphatase 1, regulatory subunit 3C |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PPP1R3C mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
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G |
Ppp2r2b |
protein phosphatase 2, regulatory subunit B, beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA |
CTD |
PMID:24690739 |
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NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
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G |
Prdx1 |
peroxiredoxin 1 |
increases expression |
ISO |
Disulfiram results in increased expression of PRDX1 mRNA; Disulfiram results in increased expression of PRDX1 protein |
CTD |
PMID:34182011 |
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NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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G |
Prok2 |
prokineticin 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PROK2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
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G |
Prss8 |
serine protease 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PRSS8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
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G |
Psat1 |
phosphoserine aminotransferase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PSAT1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
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G |
Psmc4 |
proteasome 26S subunit, ATPase 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
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G |
Pspn |
persephin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PSPN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:1,840,906...1,841,748
Ensembl chr 9:1,840,896...1,854,327
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G |
Pten |
phosphatase and tensin homolog |
multiple interactions increases expression |
ISO |
[Copper co-treated with Disulfiram] results in decreased expression of PTEN protein Disulfiram results in increased expression of PTEN mRNA |
CTD |
PMID:20424113 PMID:34182011 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptges3 |
prostaglandin E synthase 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PTGES3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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G |
Ptgr1 |
prostaglandin reductase 1 |
increases expression |
ISO |
Disulfiram results in increased expression of PTGR1 mRNA |
CTD |
PMID:20566472 |
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NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
EXP |
Disulfiram results in decreased expression of PTGS2 mRNA |
CTD |
PMID:10418820 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptma |
prothymosin alpha |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of PTMA mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
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G |
Ptx3 |
pentraxin 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of PTX3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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G |
Rab5c |
RAB5C, member RAS oncogene family |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RAB5C mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RAC1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Rai2 |
retinoic acid induced 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RAI2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr X:32,948,656...33,011,222
Ensembl chr X:32,948,656...33,011,264
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G |
Ramac |
RNA guanine-7 methyltransferase activating subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RAMAC mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:135,708,529...135,714,417
Ensembl chr 1:135,708,535...135,722,151
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G |
Rasa1 |
RAS p21 protein activator 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RASA1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
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G |
Rasd1 |
ras related dexamethasone induced 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RASD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
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G |
Rasl11b |
RAS-like family 11 member B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RASL11B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
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G |
Rbis |
ribosomal biogenesis factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RBIS mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:86,981,314...86,997,352
Ensembl chr 2:86,991,315...87,041,339
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G |
Rbm18 |
RNA binding motif protein 18 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:19,467,333...19,487,171
Ensembl chr 3:19,467,335...19,487,178
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G |
Rbm48 |
RNA binding motif protein 48 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RBM48 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:30,559,063...30,569,409
Ensembl chr 4:30,559,087...30,569,406
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G |
Rep15 |
RAB15 effector protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of REP15 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:179,951,935...179,953,008
Ensembl chr 4:179,951,935...179,953,008
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G |
Rftn1 |
raftlin lipid raft linker 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RFTN1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084
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G |
Rftn2 |
raftlin family member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RFTN2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810
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G |
Rgcc |
regulator of cell cycle |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RGCC mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
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|
G |
Rgs11 |
regulator of G-protein signaling 11 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RGS11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060
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|
G |
Rgs16 |
regulator of G-protein signaling 16 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RGS16 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
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|
G |
Rgs2 |
regulator of G-protein signaling 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RGS2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
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|
G |
Rhbdf1 |
rhomboid 5 homolog 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RHBDF1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763
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|
G |
Rhbdf2 |
rhomboid 5 homolog 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RHBDF2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283
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|
G |
Rhob |
ras homolog family member B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RHOB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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|
G |
Rnf207 |
ring finger protein 207 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RNF207 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375
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|
G |
Rpl23 |
ribosomal protein L23 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RPL23 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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|
G |
Rpl29 |
ribosomal protein L29 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RPL29 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:107,068,929...107,070,963
Ensembl chr 8:107,068,480...107,070,914
|
|
G |
Rpl38 |
ribosomal protein L38 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RPL38 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004 Ensembl chr14:99,701,362...99,705,004 Ensembl chr 3:99,701,362...99,705,004 Ensembl chr 2:99,701,362...99,705,004 Ensembl chr16:99,701,362...99,705,004
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|
G |
Rplp1 |
ribosomal protein lateral stalk subunit P1 |
increases expression |
ISO |
Disulfiram results in increased expression of RPLP1 protein |
CTD |
PMID:34182011 |
|
NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339
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|
G |
Rps15 |
ribosomal protein S15 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RPS15 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
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|
G |
Rps7 |
ribosomal protein S7 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RPS7 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
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|
G |
Rrad |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RRAD mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
|
|
G |
Rragd |
Ras-related GTP binding D |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RRAGD mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
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|
G |
Rras |
RAS related |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RRAS mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357
|
|
G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of RSAD2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
|
|
G |
RT1-CE5 |
RT1 class I, locus CE5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of HLA-F mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:3,403,418...3,479,476
|
|
G |
Runx2 |
RUNX family transcription factor 2 |
increases expression |
EXP |
Disulfiram results in increased expression of RUNX2 mRNA |
CTD |
PMID:24496638 |
|
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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|
G |
Rybp |
RING1 and YY1 binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of RYBP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316
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|
G |
Sap18 |
Sin3A associated protein 18 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:31,943,228...31,947,534
Ensembl chr15:31,943,230...31,950,038 Ensembl chr10:31,943,230...31,950,038
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|
G |
Sar1b |
secretion associated, Ras related GTPase 1B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SAR1B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:36,024,415...36,054,069
Ensembl chr10:36,024,382...36,054,066
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|
G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SAT1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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|
G |
Sbds |
Sbds, ribosome maturation factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SBDS mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649
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|
G |
Scarf2 |
scavenger receptor class F, member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SCARF2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348
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|
G |
Sec61b |
SEC61 translocon subunit beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SEC61B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804
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|
G |
Sel1l3 |
SEL1L family member 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SEL1L3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
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|
G |
Sem1 |
SEM1 26S proteasome subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SEM1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:34,671,848...34,692,005
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|
G |
Sertad1 |
SERTA domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SERTAD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
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|
G |
Sf3b4 |
splicing factor 3B subunit 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SF3B4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
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|
G |
Sgta |
small glutamine rich tetratricopeptide repeat co-chaperone alpha |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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|
G |
Sh3pxd2a |
SH3 and PX domains 2A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SH3PXD2A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166
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|
G |
Sik1 |
salt-inducible kinase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SIK1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
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|
G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SIRT1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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|
G |
Sirt6 |
sirtuin 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SIRT6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
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|
G |
Ski |
Ski proto-oncogene |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SKI mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
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|
G |
Skil |
SKI-like proto-oncogene |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SKIL mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
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|
G |
Slc16a10 |
solute carrier family 16 member 10 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SLC16A10 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
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|
G |
Slc25a37 |
solute carrier family 25 member 37 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SLC25A37 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
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|
G |
Slc30a1 |
solute carrier family 30 member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SLC30A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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|
G |
Slc44a1 |
solute carrier family 44 member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SLC44A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:68,061,941...68,241,912
Ensembl chr 5:68,063,618...68,241,909
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|
G |
Slc44a2 |
solute carrier family 44 member 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SLC44A2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:19,870,867...19,905,345
Ensembl chr 8:19,870,888...19,905,342
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|
G |
Slc6a9 |
solute carrier family 6 member 9 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SLC6A9 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
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|
G |
Slc7a1 |
solute carrier family 7 member 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SLC7A1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
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|
G |
Slc7a6os |
solute carrier family 7, member 6 opposite strand |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SLC7A6OS mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:34,101,978...34,110,666
Ensembl chr19:34,101,982...34,110,651
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|
G |
Slfn9 |
schlafen family member 9 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SLFN11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
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|
G |
Slu7 |
SLU7 homolog, splicing factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SLU7 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349
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|
G |
Smad3 |
SMAD family member 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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|
G |
Smox |
spermine oxidase |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SMOX mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
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|
G |
Snai1 |
snail family transcriptional repressor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SNAI1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snip1 |
Smad nuclear interacting protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845
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|
G |
Snrpb2 |
small nuclear ribonucleoprotein polypeptide B2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SNRPB2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
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|
G |
Sod1 |
superoxide dismutase 1 |
increases expression decreases activity |
ISO |
Disulfiram results in increased expression of SOD1 mRNA Disulfiram results in decreased activity of SOD1 protein |
CTD |
PMID:19016906 PMID:20566472 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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|
G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
ISO |
Disulfiram results in increased expression of SOD2 mRNA [Disulfiram co-treated with Zinc Sulfate] results in increased expression of SOD2 mRNA |
CTD |
PMID:20566472 PMID:32712770 PMID:34182011 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sod3 |
superoxide dismutase 3 |
increases expression |
ISO |
Disulfiram results in increased expression of SOD3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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|
G |
Sox8 |
SRY-box transcription factor 8 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SOX8 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
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|
G |
Spacdr |
sperm acrosome developmental regulator |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SPACDR mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:18,930,608...18,936,787
Ensembl chr12:18,914,398...18,952,008
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|
G |
Spata20 |
spermatogenesis associated 20 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SPATA20 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:79,427,525...79,435,472
Ensembl chr10:79,427,528...79,434,368
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|
G |
Spire1 |
spire-type actin nucleation factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SPIRE1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:61,041,914...61,171,670
Ensembl chr18:61,041,290...61,171,899
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|
G |
Spsb1 |
splA/ryanodine receptor domain and SOCS box containing 1 |
increases expression |
ISO |
Disulfiram results in increased expression of SPSB1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
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|
G |
Sptbn1 |
spectrin, beta, non-erythrocytic 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SPTBN1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
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|
G |
Spty2d1 |
SPT2 chromatin protein domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SPTY2D1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:97,531,495...97,549,616
Ensembl chr 1:97,531,508...97,549,581
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G |
Sqstm1 |
sequestosome 1 |
decreases expression |
ISO |
Disulfiram results in decreased expression of SQSTM1 protein |
CTD |
PMID:34182011 |
|
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
Disulfiram results in increased expression of SRXN1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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|
G |
Stc2 |
stanniocalcin 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of STC2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
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|
G |
Steep1 |
STING1 ER exit protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of STEEP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr X:116,087,626...116,114,159
Ensembl chr X:116,060,929...116,114,159
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|
G |
Stx3 |
syntaxin 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of STX3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
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|
G |
Sulf1 |
sulfatase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA; [Disulfiram binds to Copper] which results in increased expression of SULF1 protein |
CTD |
PMID:24690739 |
|
NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584
|
|
G |
Sumo2 |
small ubiquitin-like modifier 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SUMO2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513
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|
G |
Sun1 |
Sad1 and UNC84 domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SUN1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571
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|
G |
Sun2 |
Sad1 and UNC84 domain containing 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of SUN2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553
|
|
G |
Supt4h1 |
SPT4 homolog, DSIF elongation factor subunit |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SUPT4H1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831
|
|
G |
Synj1 |
synaptojanin 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SYNJ1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:30,192,629...30,269,447
Ensembl chr11:30,192,629...30,269,220
|
|
G |
Szrd1 |
SUZ RNA binding domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of SZRD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:153,418,748...153,443,286
Ensembl chr 5:153,418,748...153,443,252
|
|
G |
Taf13 |
TATA-box binding protein associated factor 13 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TAF13 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878
|
|
G |
Taf7 |
TATA-box binding protein associated factor 7 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TAF7 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134
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|
G |
Tamalin |
trafficking regulator and scaffold protein tamalin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TAMALIN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:132,338,900...132,359,519
Ensembl chr 7:132,338,900...132,346,666
|
|
G |
Tanc1 |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627
|
|
G |
Tap2 |
transporter 2, ATP binding cassette subfamily B member |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TAP2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
|
|
G |
Tapbp |
TAP binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TAPBP mRNA |
CTD |
PMID:24690739 |
|
NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181
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|
G |
Tat |
tyrosine aminotransferase |
multiple interactions |
EXP |
[Ethanol co-treated with Disulfiram] results in increased activity of TAT protein |
CTD |
PMID:9591243 |
|
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
|
|
G |
Tcea2 |
transcription elongation factor A2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TCEA2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:168,796,331...168,804,116
|
|
G |
Tcp1 |
t-complex 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TCP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
|
|
G |
Tent5b |
terminal nucleotidyltransferase 5B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TENT5B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073
|
|
G |
Tent5c |
terminal nucleotidyltransferase 5C |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TENT5C mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
|
|
G |
Tfip11 |
tuftelin interacting protein 11 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TFIP11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:44,299,619...44,311,851
Ensembl chr12:44,299,622...44,311,855
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
decreases activity |
ISO |
Disulfiram results in decreased activity of TGFB1 protein |
CTD |
PMID:31652400 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
|
|
G |
Thap1 |
THAP domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of THAP1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942
|
|
G |
Them6 |
thioesterase superfamily member 6 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of THEM6 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746
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|
G |
Thra |
thyroid hormone receptor alpha |
multiple interactions |
ISO |
Disulfiram binds to and results in increased activity of THRA protein |
CTD |
PMID:33049310 |
|
NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
|
|
G |
Ticam2 |
TIR domain containing adaptor molecule 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TICAM2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
|
|
G |
Tmem167a |
transmembrane protein 167A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TMEM167A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:21,197,799...21,216,746
Ensembl chr 2:21,197,786...21,212,099
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|
G |
Tmem175 |
transmembrane protein 175 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TMEM175 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
|
|
G |
Tmem208 |
transmembrane protein 208 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TMEM208 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:33,203,587...33,206,287
Ensembl chr19:33,203,587...33,212,183
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|
G |
Tmem35b |
transmembrane protein 35B |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TMEM35B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:139,446,317...139,449,947
Ensembl chr 5:139,444,399...139,449,947
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|
G |
Tmem42 |
transmembrane protein 42 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TMEM42 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276
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|
G |
Tmem43 |
transmembrane protein 43 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TMEM43 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:123,977,680...123,992,823
Ensembl chr 4:123,977,625...123,992,825
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|
G |
Tmem44 |
transmembrane protein 44 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TMEM44 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:70,181,120...70,216,958
Ensembl chr11:70,181,345...70,216,958
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|
G |
Tnf |
tumor necrosis factor |
decreases expression increases secretion multiple interactions |
EXP ISO |
Disulfiram results in decreased expression of TNF mRNA Disulfiram results in increased secretion of TNF protein [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; Disulfiram promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] |
CTD |
PMID:10418820 PMID:19016906 PMID:32712770 PMID:33851234 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
G |
Tnfsf10 |
TNF superfamily member 10 |
increases expression |
ISO |
Disulfiram results in increased expression of TNFSF10 mRNA |
CTD |
PMID:34182011 |
|
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
|
|
G |
Tnip1 |
TNFAIP3 interacting protein 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TNIP1 protein |
CTD |
PMID:24690739 |
|
NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625
|
|
G |
Tnip2 |
TNFAIP3 interacting protein 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TNIP2 protein |
CTD |
PMID:24690739 |
|
NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265
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|
G |
Tns3 |
tensin 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TNS3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
|
|
G |
Tprkb |
Tp53rk binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TPRKB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 4:118,342,910...118,357,908
Ensembl chr 4:118,342,945...118,357,901
|
|
G |
Tpsab1 |
tryptase alpha/beta 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TPSAB1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:14,360,396...14,362,811
Ensembl chr10:14,360,396...14,362,811
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|
G |
Tra2b |
transformer 2 beta |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TRA2B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249
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|
G |
Trabd |
TraB domain containing |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TRABD mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:120,155,042...120,166,015
Ensembl chr 7:120,155,042...120,166,015
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|
G |
Trh |
thyrotropin releasing hormone |
multiple interactions increases expression decreases expression |
EXP |
Dexamethasone promotes the reaction [Disulfiram results in decreased expression of TRH protein] Disulfiram results in increased expression of TRH mRNA alternative form |
CTD |
PMID:9681491 |
|
NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
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|
G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions decreases secretion |
EXP |
Dexamethasone promotes the reaction [Disulfiram results in decreased secretion of TSHB protein] |
CTD |
PMID:9681491 |
|
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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|
G |
Tspyl2 |
TSPY-like 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr X:21,439,478...21,445,208
Ensembl chr X:21,439,478...21,445,089
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|
G |
Ttc13 |
tetratricopeptide repeat domain 13 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of TTC13 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:52,637,599...52,692,196
Ensembl chr19:52,637,431...52,692,198
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|
G |
Ttf1 |
transcription termination factor 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TTF1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:12,384,626...12,409,257
Ensembl chr 3:12,384,655...12,409,257
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|
G |
Tuba4a |
tubulin, alpha 4A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TUBA4A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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|
G |
Tubb2a |
tubulin, beta 2A class IIa |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TUBB2A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
|
|
G |
Tubb2b |
tubulin, beta 2B class IIb |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TUBB2B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
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|
G |
Tubb3 |
tubulin, beta 3 class III |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TUBB3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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|
G |
Txn2 |
thioredoxin 2 |
increases expression |
ISO |
Disulfiram results in increased expression of TXN2 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
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|
G |
Txnl1 |
thioredoxin-like 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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|
G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
Disulfiram results in increased expression of TXNRD1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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|
G |
Txnrd2 |
thioredoxin reductase 2 |
increases expression |
ISO |
Disulfiram results in increased expression of TXNRD2 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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|
G |
Ubfd1 |
ubiquitin family domain containing 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of UBFD1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:176,626,003...176,640,993
Ensembl chr 1:176,625,657...176,640,993
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|
G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
increases expression |
ISO |
Disulfiram results in increased expression of UGT1A6 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
|
|
G |
Ulk1 |
unc-51 like autophagy activating kinase 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ULK1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
|
|
G |
Uqcc4 |
ubiquinol-cytochrome c reductase complex assembly factor 4 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of UQCC4 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:14,202,217...14,203,519
Ensembl chr10:14,202,243...14,204,029
|
|
G |
Uqcrb |
ubiquinol-cytochrome c reductase binding protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of UQCRB mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150
|
|
G |
Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of UQCRH mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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|
G |
Uspl1 |
ubiquitin specific peptidase like 1 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of USPL1 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:5,823,460...5,850,470
Ensembl chr12:5,823,359...5,850,366
|
|
G |
Utp11 |
UTP11, small subunit processome component |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of UTP11 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:136,931,279...136,946,164
Ensembl chr 5:136,931,008...136,946,191
|
|
G |
Utp3 |
UTP3, small subunit processome component |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of UTP3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396
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|
G |
Vcan |
versican |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of VCAN mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
|
|
G |
Vcl |
vinculin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of VCL mRNA |
CTD |
PMID:24690739 |
|
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
|
|
G |
Vdac1 |
voltage-dependent anion channel 1 |
multiple interactions |
ISO |
VDAC1 protein results in increased susceptibility to [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] |
CTD |
PMID:24126434 |
|
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
|
|
G |
Vegfc |
vascular endothelial growth factor C |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of VEGFC mRNA |
CTD |
PMID:24690739 |
|
NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
|
|
G |
Vgf |
VGF nerve growth factor inducible |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of VGF mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
|
|
G |
Vim |
vimentin |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased cleavage of VIM protein |
CTD |
PMID:24690739 |
|
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
|
|
G |
Vps37b |
VPS37B subunit of ESCRT-I |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of VPS37B mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:32,560,047...32,589,015
Ensembl chr12:32,560,047...32,589,014
|
|
G |
Wdr20 |
WD repeat domain 20 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of WDR20 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 6:129,751,952...129,821,464
Ensembl chr 6:129,752,014...129,847,339
|
|
G |
Xylt2 |
xylosyltransferase 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of XYLT2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
|
|
G |
Yju2 |
YJU2 splicing factor |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of YJU2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 9:789,603...799,505
Ensembl chr 9:789,606...799,496
|
|
G |
Zbtb43 |
zinc finger and BTB domain containing 43 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZBTB43 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:16,744,535...16,763,854
Ensembl chr 3:16,744,535...16,763,909
|
|
G |
Zfand2a |
zinc finger AN1-type containing 2A |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZFAND2A mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
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G |
Zfp105 |
zinc finger protein 105 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF35 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:122,567,229...122,578,696
Ensembl chr 8:122,567,214...122,578,692
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G |
Zfp143 |
zinc finger protein 143 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF143 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:164,109,041...164,144,902
Ensembl chr 1:164,109,116...164,144,902
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G |
Zfp217 |
zinc finger protein 217 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ZNF217 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040
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G |
Zfp26 |
zinc finger protein 26 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF778 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 8:18,959,656...18,985,647
Ensembl chr 8:18,965,271...18,988,325
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G |
Zfp34 |
zinc finger protein 34 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF34 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 5:157,509,762...157,513,970
Ensembl chr 5:157,509,451...157,599,926
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G |
Zfp36 |
zinc finger protein 36 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZFP36 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
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G |
Zfp622 |
zinc finger protein 622 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF622 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 2:76,479,605...76,494,405
Ensembl chr 2:76,335,609...76,493,898
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G |
Zfp77 |
zinc finger protein 77 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF77 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 7:7,269,879...7,316,286
Ensembl chr 7:7,269,927...7,286,051
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G |
Zhx3 |
zinc fingers and homeoboxes 3 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in increased expression of ZHX3 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:149,417,787...149,548,671
Ensembl chr 3:149,417,818...149,527,079
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G |
Zkscan5 |
zinc finger with KRAB and SCAN domains 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZKSCAN5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr12:9,384,561...9,405,763
Ensembl chr12:9,384,571...9,405,881
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G |
Zmat2 |
zinc finger, matrin type 2 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZMAT2 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr18:28,409,606...28,414,241
Ensembl chr18:28,398,795...28,414,747
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G |
Zmat5 |
zinc finger, matrin type 5 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZMAT5 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr14:79,568,644...79,599,595
Ensembl chr14:79,568,758...79,599,594
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G |
Znf408 |
zinc finger protein 408 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZNF408 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr 3:77,615,595...77,621,325
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G |
Zscan26 |
zinc finger and SCAN domain containing 26 |
multiple interactions |
ISO |
[Disulfiram binds to Copper] which results in decreased expression of ZSCAN26 mRNA |
CTD |
PMID:24690739 |
|
NCBI chr17:43,148,063...43,168,070
Ensembl chr17:43,148,079...43,168,070
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of ACTA2 mRNA]; lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of ACTA2 protein] |
CTD |
PMID:34537180 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form] |
CTD |
PMID:29969931 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
AHR affects the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA] |
CTD |
PMID:16415877 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions affects abundance |
EXP |
zileuton inhibits the reaction [ALOX5 protein affects the abundance of lipoxin A4] |
CTD |
PMID:15326064 |
|
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein] |
CTD |
PMID:23063943 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein] |
CTD |
PMID:23063943 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression |
EXP |
Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of CASP3 protein] |
CTD |
PMID:36057361 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of COL1A1 mRNA] |
CTD |
PMID:34537180 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of COL1A2 protein] |
CTD |
PMID:34537180 |
|
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of CXCL2 protein] |
CTD |
PMID:10377187 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Fpr2 |
formyl peptide receptor 2 |
multiple interactions increases activity |
ISO EXP |
[Aspirin results in increased abundance of lipoxin A4] which results in increased expression of FPR2; lipoxin A4 analog binds to and results in decreased activity of FPR2 protein lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of FPR2 mRNA] lipoxin A4 results in increased activity of FPR2 |
CTD |
PMID:12594298 PMID:19597002 PMID:21765620 |
|
NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP |
lipoxin A4 results in increased expression of HMOX1 mRNA; lipoxin A4 results in increased expression of HMOX1 protein lipoxin A4 promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer] |
CTD |
PMID:23826208 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Icam1 |
intercellular adhesion molecule 1 |
affects response to substance increases expression multiple interactions |
ISO EXP |
ICAM1 protein affects the susceptibility to lipoxin A4 lipoxin A4 results in increased expression of ICAM1 protein Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of ICAM1 protein] |
CTD |
PMID:7602232 PMID:36057361 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein] |
CTD |
PMID:29969931 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il13 |
interleukin 13 |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] |
CTD |
PMID:34537180 |
|
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il1b |
interleukin 1 beta |
decreases expression multiple interactions decreases secretion |
ISO |
lipoxin A4 analog results in decreased expression of IL1B protein 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] lipoxin A4 analog results in decreased secretion of IL1B protein lipoxin A4 analog inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [TNF protein results in increased secretion of IL1B protein] |
CTD |
PMID:10377187 PMID:21659618 PMID:21831303 PMID:29969931 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il4 |
interleukin 4 |
increases secretion multiple interactions |
ISO |
lipoxin A4 analog results in increased secretion of IL4 protein lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] |
CTD |
PMID:10377187 PMID:34537180 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] |
CTD |
PMID:34537180 |
|
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL6 protein] |
CTD |
PMID:27663891 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:21831303 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:21831303 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
EXP |
Gentamicins inhibits the reaction [lipoxin A4 results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:36057361 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mas1 |
MAS1 proto-oncogene, G protein-coupled receptor |
multiple interactions |
ISO |
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA]; 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein]]; [lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein] |
CTD |
PMID:29969931 |
|
NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein] |
CTD |
PMID:29969931 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
affects localization multiple interactions |
EXP |
lipoxin A4 affects the localization of NFE2L2 protein lipoxin A4 promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer] |
CTD |
PMID:23826208 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] |
CTD |
PMID:21831303 PMID:29969931 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:21831303 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions |
ISO |
lipoxin A4 affects the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; PDGFB protein promotes the reaction [lipoxin A4 results in decreased phosphorylation of PDGFRB protein] |
CTD |
PMID:12223454 PMID:20709806 |
|
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
multiple interactions decreases phosphorylation |
ISO |
lipoxin A4 affects the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; lipoxin A4 inhibits the reaction [Leukotriene D4 results in increased activity of PDGFRB protein]; PDGFB protein promotes the reaction [lipoxin A4 results in decreased phosphorylation of PDGFRB protein] |
CTD |
PMID:12223454 PMID:20709806 |
|
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
EXP |
lipoxin A4 binds to and results in increased activity of PPARG protein |
CTD |
PMID:19321784 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptafr |
platelet-activating factor receptor |
multiple interactions |
ISO |
[WEB 2086 binds to and results in decreased activity of PTAFR protein] which results in decreased susceptibility to lipoxin A4 |
CTD |
PMID:7602232 |
|
NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions affects abundance |
EXP |
[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTGS2 protein; Celecoxib inhibits the reaction [PTGS2 protein affects the abundance of lipoxin A4]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] |
CTD |
PMID:15326064 PMID:21765620 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] |
CTD |
PMID:21831303 PMID:23063943 PMID:29969931 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Selp |
selectin P |
affects response to substance |
ISO |
SELP protein affects the susceptibility to lipoxin A4 |
CTD |
PMID:7602232 |
|
NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions increases expression |
ISO |
AHR affects the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA] lipoxin A4 results in increased expression of SOCS2 mRNA; lipoxin A4 results in increased expression of SOCS2 protein |
CTD |
PMID:16415877 |
|
NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
lipoxin A4 inhibits the reaction [Ovalbumin results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:34537180 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
EXP |
lipoxin A4 results in increased expression of TGFB1 protein Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of TGFB1 protein] |
CTD |
PMID:36057361 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO EXP |
lipoxin A4 analog inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; lipoxin A4 inhibits the reaction [TNF protein results in increased secretion of IL1B protein] Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of TNF protein] 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of CXCL2 protein]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:10377187 PMID:21575454 PMID:21831303 PMID:23063943 PMID:29969931 PMID:36057361 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of AHR protein |
CTD |
PMID:27633901 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of ESR1 protein |
CTD |
PMID:27633901 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of PPARG protein |
CTD |
PMID:27633901 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Dbi |
diazepam binding inhibitor |
affects binding |
ISO |
S-tetradecanoyl-coenzyme A binds to DBI protein |
CTD |
PMID:17044054 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
EXP |
N-oleoyldopamine binds to and results in increased activity of CNR1 protein |
CTD |
PMID:12569099 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases activity |
ISO EXP |
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [N-oleoyldopamine results in increased activity of TRPV1 protein] |
CTD |
PMID:12569099 PMID:15615864 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression increases phosphorylation increases degradation |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ABCA1 mRNA; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] Oleic Acid results in increased expression of ABCA1 mRNA Oleic Acid results in increased phosphorylation of ABCA1 protein Oleic Acid results in increased degradation of ABCA1 protein Oleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] |
CTD |
PMID:16118212 PMID:18356535 PMID:30547786 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
increases expression |
EXP |
Oleic Acid results in increased expression of ABCB11 mRNA |
CTD |
PMID:32738331 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of ABCG1 mRNA; Oleic Acid results in decreased expression of ABCG1 protein |
CTD |
PMID:16730733 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression |
ISO |
Oleic Acid results in increased expression of ABCG2 mRNA |
CTD |
PMID:22819932 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Acaa1a |
acetyl-CoA acyltransferase 1A |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
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G |
Acaa2 |
acetyl-CoA acyltransferase 2 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAA2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA Oleic Acid results in increased expression of ACAA2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA; cyhalothrin promotes the reaction [Oleic Acid results in increased expression of ACACA protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA] |
CTD |
PMID:30611723 PMID:36529352 PMID:36905866 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acacb |
acetyl-CoA carboxylase beta |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACB mRNA |
CTD |
PMID:30611723 |
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NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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G |
Acad9 |
acyl-CoA dehydrogenase family, member 9 |
multiple interactions increases expression |
ISO |
[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of ACAD9 mRNA] |
CTD |
PMID:31340670 |
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NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA |
CTD |
PMID:26190035 PMID:30611723 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acads |
acyl-CoA dehydrogenase short chain |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADS mRNA Oleic Acid results in increased expression of ACADS mRNA |
CTD |
PMID:30611723 |
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NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADVL mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADVL mRNA |
CTD |
PMID:30611723 |
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NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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G |
Acly |
ATP citrate lyase |
multiple interactions decreases expression |
ISO |
[[Vehicle Emissions results in increased abundance of Particulate Matter] which co-treated with Oleic Acid] results in decreased expression of ACLY mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACLY mRNA Oleic Acid results in decreased expression of ACLY mRNA |
CTD |
PMID:30611723 PMID:31340670 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acot12 |
acyl-CoA thioesterase 12 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT12 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA Oleic Acid results in increased expression of ACOT12 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
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G |
Acot4 |
acyl-CoA thioesterase 4 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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G |
Acot6 |
acyl-CoA thioesterase 6 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446
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G |
Acot7 |
acyl-CoA thioesterase 7 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT7 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT7 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
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G |
Acot8 |
acyl-CoA thioesterase 8 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
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G |
Acox1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [tesaglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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G |
Acox2 |
acyl-CoA oxidase 2 |
multiple interactions decreases expression |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA Oleic Acid results in decreased expression of ACOX2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ACSL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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G |
Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ACTA2 mRNA Oleic Acid results in increased expression of ACTA2 mRNA |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of ADIPOQ mRNA sophocarpine inhibits the reaction [Oleic Acid results in decreased expression of ADIPOQ mRNA] |
CTD |
PMID:23395669 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor2 |
adiponectin receptor 2 |
decreases expression |
EXP |
oleic acid cotreated with ethanol decreases expression of adipor2 mRNA in rat primary hepatocytes |
RGD |
PMID:21194380 |
RGD:24922202 |
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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G |
Agpat1 |
1-acylglycerol-3-phosphate O-acyltransferase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278
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G |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of AGPAT2 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AGPAT2 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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G |
Agpat5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:70,939,480...70,985,745
Ensembl chr16:70,943,135...70,985,560
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AHR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases phosphorylation |
EXP ISO |
Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:14604813 PMID:25536389 PMID:26847930 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions affects binding decreases secretion |
ISO |
[ALB protein binds to Oleic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Oleic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Oleic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [Oleic Acid co-treated with muraglitazar] results in increased expression of ALB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ALB mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ALB mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein]; Quercetin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein] |
CTD |
PMID:23348005 PMID:24534255 PMID:25451573 PMID:38103844 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Anxa2 |
annexin A2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ANXA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] |
CTD |
PMID:16118212 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoa4 |
apolipoprotein A4 |
increases expression |
ISO |
Oleic Acid results in increased expression of APOA4 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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G |
Apoa5 |
apolipoprotein A5 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of APOA5 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
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G |
Apob |
apolipoprotein B |
multiple interactions decreases expression increases expression |
ISO EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of APOB protein]; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]; Oleic Acid results in increased expression of and results in increased secretion of APOB protein Oleic Acid results in decreased expression of APOB mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]; Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] |
CTD |
PMID:12048068 PMID:15618547 PMID:17237316 PMID:19383982 PMID:26854922 PMID:30611723 PMID:32918399 More...
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoc3 |
apolipoprotein C3 |
multiple interactions |
ISO |
[Oleic Acid co-treated with muraglitazar] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with rosiglitazone] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of APOC3 mRNA |
CTD |
PMID:24534255 |
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NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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G |
Apoc4 |
apolipoprotein C4 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOE mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOE mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Arg1 |
arginase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ARG1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of ATF6 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein] |
CTD |
PMID:36905866 |
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein] |
CTD |
PMID:36905866 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
B4galt5 |
beta-1,4-galactosyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of B4GALT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
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G |
Bace1 |
beta-secretase 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein] |
CTD |
PMID:37009739 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA |
CTD |
PMID:32369900 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA |
CTD |
PMID:32369900 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
multiple interactions increases cleavage |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA Oleic Acid results in increased cleavage of CASP3 protein Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased cleavage of CASP3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:36273635 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions increases cleavage |
EXP ISO |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA |
CTD |
PMID:14604813 PMID:32369900 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions increases activity decreases activity |
ISO EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; Quercetin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein] Oleic Acid results in increased activity of CAT protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased activity of CAT protein; [Oleic Acid co-treated with Palmitic Acid] results in increased activity of CAT protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased activity of CAT protein]; gossypin inhibits the reaction [Oleic Acid results in increased activity of CAT protein] |
CTD |
PMID:23348005 PMID:26854922 PMID:30547786 PMID:37696682 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav2 |
caveolin 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CAV2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO EXP |
GW 4064 inhibits the reaction [Oleic Acid results in increased expression of CD36 protein] Oleic Acid results in increased expression of CD36 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA] [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA |
CTD |
PMID:23371517 PMID:28552552 PMID:30611723 PMID:36347319 PMID:38092172 PMID:38103844 More...
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA |
CTD |
PMID:32369900 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cidec |
cell death-inducing DFFA-like effector c |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CIDEC mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Cox10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of COX10 mRNA |
CTD |
PMID:30611723 |
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NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression decreases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of CPT1A mRNA Oleic Acid results in decreased expression of CPT1A mRNA [Starch co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of CPT1A mRNA [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT1A mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of CPT1A mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] |
CTD |
PMID:11171094 PMID:24534255 PMID:25048947 PMID:26190035 PMID:26854922 PMID:26895660 PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 More...
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of CPT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Crebbp |
CREB binding protein |
decreases expression |
EXP |
Oleic Acid results in decreased expression of CREBBP mRNA |
CTD |
PMID:24349266 |
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NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crp |
C-reactive protein |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein |
CTD |
PMID:17237316 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL10 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with letrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein |
CTD |
PMID:24161488 PMID:27016407 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of CYP1A1 mRNA; Oleic Acid results in increased expression of CYP1A1 protein [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 mRNA]; [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 protein] |
CTD |
PMID:31730885 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of CYP1A2 mRNA Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP24A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of CYP2B6 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP2B6 mRNA] |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA] Oleic Acid results in increased expression of CYP2E1 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:26854922 PMID:30611723 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions decreases expression |
ISO |
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP3A4 mRNA] Oleic Acid results in decreased expression of CYP3A4 mRNA; Oleic Acid results in decreased expression of CYP3A4 protein |
CTD |
PMID:26739624 PMID:30611723 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:26854922 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression multiple interactions |
EXP ISO |
Oleic Acid results in decreased expression of CYP7A1 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:32738331 PMID:38103844 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 mRNA]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:37009739 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Decr1 |
2,4-dienoyl-CoA reductase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of DECR1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
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G |
Derl1 |
derlin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of DGAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of DGAT2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Dhdds |
dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DHDDS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of DHDDS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454
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G |
Dnm1l |
dynamin 1-like |
affects phosphorylation |
ISO |
Oleic Acid affects the phosphorylation of DNM1L protein |
CTD |
PMID:36273635 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dst |
dystonin |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DST mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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G |
Dync1h1 |
dynein cytoplasmic 1 heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1H1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1I1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of E2F1 protein |
CTD |
PMID:16027227 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Ech1 |
enoyl-CoA hydratase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECH1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of ECH1 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECHS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of EDN1 mRNA; Oleic Acid results in decreased expression of EDN1 protein |
CTD |
PMID:16895544 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein] Oleic Acid results in increased phosphorylation of EGFR protein |
CTD |
PMID:27447558 PMID:30547786 PMID:38103844 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of EHHADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EIF2AK3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA |
CTD |
PMID:30547786 PMID:32369900 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ELOVL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ELOVL6 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ELOVL6 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Eno3 |
enolase 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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G |
Erlin1 |
ER lipid raft associated 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp1 |
fatty acid binding protein 1 |
affects binding multiple interactions decreases expression |
EXP ISO |
Oleic Acid binds to FABP1 protein Oleic acid binds to Fabp1 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FABP1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FABP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of FABP1 mRNA; Dibutyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Oleic Acid inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] Bezafibrate inhibits the reaction [Oleic Acid binds to FABP1 protein] |
CTD RGD |
PMID:2328261 PMID:30547786 PMID:30611723 PMID:31110286 PMID:38092172 PMID:1939124 More...
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RGD:1626448 |
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp2 |
fatty acid binding protein 2 |
affects binding |
EXP |
FABP2 protein modified form binds to Oleic Acid |
CTD |
PMID:16137630 |
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NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions affects localization increases expression |
ISO |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of FABP4 mRNA Oleic Acid analog affects the localization of FABP4 protein Oleic Acid results in increased expression of FABP4 mRNA |
CTD |
PMID:8536680 PMID:26739624 PMID:27939595 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FAS mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein] Oleic Acid results in increased expression of FAS mRNA |
CTD |
PMID:26190035 PMID:32918399 PMID:36347319 PMID:36905866 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO EXP |
[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of FASN mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FASN mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein; [Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein] [Sucrose co-treated with Oleic Acid] results in increased expression of FASN mRNA [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA |
CTD |
PMID:24534255 PMID:26854922 PMID:26895660 PMID:30611723 PMID:33508418 PMID:36529352 PMID:38103844 More...
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FDFT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FDFT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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G |
Fdps |
farnesyl diphosphate synthase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of FDPS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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G |
Ffar1 |
free fatty acid receptor 1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of FFAR1 mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FGF21 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Flot1 |
flotillin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
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G |
Fnta |
farnesyltransferase, CAAX box, subunit alpha |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of FNTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
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G |
Fntb |
farnesyltransferase, CAAX box, subunit beta |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
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G |
Foxa1 |
forkhead box A1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FOXA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of FOXO1 protein; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein] |
CTD |
PMID:32976958 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] |
CTD |
PMID:26847930 |
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NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gcg |
glucagon |
multiple interactions increases secretion |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein] |
CTD |
PMID:36905866 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] |
CTD |
PMID:36905866 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Ggps1 |
geranylgeranyl diphosphate synthase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of GGPS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GGT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions affects localization |
EXP |
[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein; Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; Chloroquine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; exenatide inhibits the reaction [[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein]; Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein; wortmannin inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] Oleic Acid affects the localization of GLP1R protein |
CTD |
PMID:22925809 |
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NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
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G |
Gnat3 |
G protein subunit alpha transducin 3 |
multiple interactions |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein; acadesine inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein] |
CTD |
PMID:33508418 |
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NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of GPAT3 mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT3 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of GPAT3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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G |
Gpat4 |
glycerol-3-phosphate acyltransferase 4 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein] |
CTD |
PMID:32976958 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein] |
CTD |
PMID:32976958 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
ISO |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:25536389 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GSTA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Hadh |
hydroxyacyl-CoA dehydrogenase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADH mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of HADHA mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADHA mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHA mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHA mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHB mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHB mRNA]; Oleic Acid promotes the reaction [GW 7647 results in increased expression of HADHB mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases secretion |
ISO |
Oleic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:31686351 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HIF1A protein |
CTD |
PMID:30547786 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HILPDA protein |
CTD |
PMID:30547786 |
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NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HMGCR mRNA [[Palmitic Acid co-treated with Oleic Acid] co-treated with IFNA2 protein alternative form] results in decreased expression of HMGCR protein |
CTD |
PMID:30611723 PMID:31299271 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
multiple interactions |
ISO |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of HMGCS1 mRNA |
CTD |
PMID:36423729 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] |
CTD |
PMID:26634892 PMID:32976958 PMID:36905866 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
multiple interactions increases expression |
EXP ISO |
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of HNF4A protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HNF4A mRNA |
CTD |
PMID:23395669 PMID:30547786 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HSDL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of HSPA5 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of HSPA5 mRNA]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA |
CTD |
PMID:24349266 PMID:30547786 PMID:32976987 PMID:37009739 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein |
CTD |
PMID:36423729 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL1B protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA] |
CTD |
PMID:26190035 PMID:36423729 PMID:37009739 PMID:37696682 PMID:38103844 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression decreases expression |
EXP ISO |
3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein; Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein] Oleic Acid results in decreased expression of IL6 mRNA Oleic Acid results in increased expression of IL6 mRNA; Oleic Acid results in increased expression of IL6 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of IL6 protein] |
CTD |
PMID:25348860 PMID:26634892 PMID:30611723 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions increases secretion |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] Oleic Acid results in increased secretion of INS1 protein Oleic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:24349266 PMID:26847930 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased uptake of Oleic Acid |
CTD |
PMID:10777552 PMID:11292061 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insr |
insulin receptor |
decreases phosphorylation multiple interactions |
ISO |
Oleic Acid results in decreased phosphorylation of INSR protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:25536389 |
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NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions |
EXP |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein]; Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] |
CTD |
PMID:14604813 |
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NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of JAK1 protein |
CTD |
PMID:30547786 |
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NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of LAMB1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lep |
leptin |
decreases expression increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of LEP mRNA Oleic Acid results in increased expression of LEP mRNA sophocarpine inhibits the reaction [Oleic Acid results in increased expression of LEP mRNA] |
CTD |
PMID:9002984 PMID:23395669 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases expression |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid Oleic Acid results in decreased expression of LIPC mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of LIPC mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LIPC mRNA; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of LIPC mRNA] |
CTD |
PMID:24777581 PMID:30611723 PMID:32918399 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid |
CTD |
PMID:24777581 |
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NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lox |
lysyl oxidase |
increases activity |
ISO |
Oleic Acid results in increased activity of LOX protein |
CTD |
PMID:26240151 |
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NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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G |
Lpin1 |
lipin 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of LPIN1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Lpin2 |
lipin 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
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G |
Lpin3 |
lipin 3 |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of LPIN3 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of MAP1LC3B mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:30547786 PMID:36905866 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
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G |
Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
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G |
Mcat |
malonyl-CoA-acyl carrier protein transacylase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MCAT mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MCAT mRNA |
CTD |
PMID:30611723 |
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NCBI chr 7:114,693,612...114,705,677
Ensembl chr 7:114,693,612...114,704,542
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G |
Mecr |
mitochondrial trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
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G |
Mff |
mitochondrial fission factor |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA |
CTD |
PMID:32369900 |
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NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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G |
Mgll |
monoglyceride lipase |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] affects the reaction [Chlorpyrifos results in decreased activity of MGLL protein] |
CTD |
PMID:35151815 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mir497 |
microRNA 497 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA] |
CTD |
PMID:37009739 |
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NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
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G |
Mlkl |
mixed lineage kinase domain like pseudokinase |
multiple interactions increases phosphorylation |
ISO |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein] |
CTD |
PMID:36273635 |
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NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
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G |
Mlxipl |
MLX interacting protein-like |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA |
CTD |
PMID:30611723 |
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NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MMP2 mRNA |
CTD |
PMID:26187275 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein] |
CTD |
PMID:38103844 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mt2A |
metallothionein 2A |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT2A mRNA |
CTD |
PMID:26854922 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions decreases expression |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MTTP mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of MTTP mRNA] |
CTD |
PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 PMID:38092172 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
ISO |
[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA] Oleic Acid results in increased expression of NFE2L2 mRNA; Oleic Acid results in increased expression of NFE2L2 protein |
CTD |
PMID:26634892 PMID:26847930 PMID:28555106 PMID:32976958 PMID:36905866 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of NOS3 mRNA |
CTD |
PMID:16895544 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein] |
CTD |
PMID:36905866 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
decreases expression increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of NR0B2 mRNA Oleic Acid results in increased expression of NR0B2 mRNA [Farnesol analog co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of NR0B2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA |
CTD |
PMID:30611723 PMID:32738331 |
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NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with tesaglitazar] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1H3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of NR1H3 mRNA |
CTD |
PMID:24534255 PMID:26190035 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of NR1H4 mRNA; [Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of NR1H4 mRNA Oleic Acid results in decreased expression of NR1H4 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1I3 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] |
CTD |
PMID:25348860 |
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NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage increases activity multiple interactions |
ISO |
Oleic Acid results in increased cleavage of PARP1 protein Oleic Acid results in increased activity of PARP1 protein [NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in increased activity of PARP1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:21132278 PMID:25536389 PMID:30165350 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pc |
pyruvate carboxylase |
decreases expression |
EXP |
Oleic Acid results in decreased expression of PC mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression |
ISO |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of PCK1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PCK1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 PMID:9518257 PMID:26847930 PMID:30611723 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions increases expression |
ISO |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of PDGFB mRNA] |
CTD |
PMID:32918399 |
|
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of PDK4 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 protein |
CTD |
PMID:26739624 PMID:30547786 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdss1 |
decaprenyl diphosphate synthase subunit 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PDSS1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PDSS1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
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G |
Pebp1 |
phosphatidylethanolamine binding protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PEBP1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of PECR mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of PECR mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
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G |
Pgam5 |
PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
multiple interactions |
ISO |
PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PIK3C2A mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Pklr |
pyruvate kinase L/R |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PKLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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G |
Pld1 |
phospholipase D1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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G |
Plek |
pleckstrin |
multiple interactions |
ISO |
Oleic Acid promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Oleic Acid results in increased expression of PLIN1 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plin2 |
perilipin 2 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN2 mRNA; Oleic Acid promotes the reaction [LG 100268 results in increased expression of PLIN2 protein]; Oleic Acid promotes the reaction [pirinixic acid results in increased expression of PLIN2 protein] Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein] Oleic Acid results in increased expression of PLIN2 mRNA; Oleic Acid results in increased expression of PLIN2 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 protein; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:16489205 PMID:24534255 PMID:25048947 PMID:26739624 PMID:30547786 PMID:30611723 PMID:31570772 PMID:38092172 More...
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plin3 |
perilipin 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN3 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
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G |
Plin4 |
perilipin 4 |
multiple interactions increases expression |
ISO |
Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA] |
CTD |
PMID:24534255 |
|
NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
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G |
Plin5 |
perilipin 5 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] |
CTD |
PMID:25048947 |
|
NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
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G |
Plpp6 |
phospholipid phosphatase 6 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949
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G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PNPLA3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
[Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [Hydrogen Peroxide results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] Oleic Acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15104111 PMID:15375178 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions affects binding increases expression affects abundance decreases expression increases activity |
ISO EXP |
Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Oleic Acid]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid inhibits the reaction [troglitazone results in decreased expression of PPARA mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP2C65 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] Oleic Acid binds to PPARA protein Oleic Acid results in increased expression of PPARA mRNA; Oleic Acid results in increased expression of PPARA protein [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARA mRNA; [tetrabromobisphenol A co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] Oleic Acid results in decreased expression of PPAR mRNA; Oleic Acid results in decreased expression of PPARA mRNA; Oleic Acid results in decreased expression of PPARA protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PPARA mRNA; [Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of PPARA mRNA]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased activity of and results in increased localization of PPARA protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PPARA protein]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid results in increased activity of and results in increased localization of PPARA protein; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein] Oleic Acid results in increased activity of PPARA protein |
CTD |
PMID:9688458 PMID:10403814 PMID:11056218 PMID:15491415 PMID:15949695 PMID:16731579 PMID:18154422 PMID:18489776 PMID:23603006 PMID:23619606 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30547786 PMID:30611723 PMID:31340670 PMID:31730885 PMID:33508418 PMID:35752307 PMID:36347319 PMID:38103844 More...
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression multiple interactions decreases expression |
ISO EXP |
Oleic Acid results in increased expression of PPARD mRNA Oleic Acid binds to and results in increased activity of PPARB protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; Oleic Acid binds to and results in increased activity of PPARB protein; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA] Oleic Acid results in decreased expression of PPARD mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNA; Oleic Acid binds to and results in increased activity of PPARB protein |
CTD |
PMID:11172467 PMID:16731579 PMID:24349266 PMID:25048947 PMID:26190035 PMID:26854922 PMID:30547786 More...
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression affects binding multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of PPARG mRNA Oleic Acid binds to PPARG protein [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of PPARG mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA] [cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARG mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARG mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein]; Oleic Acid binds to and results in increased activity of PPARG protein Oleic Acid results in increased expression of PPARG mRNA; Oleic Acid results in increased expression of PPARG protein |
CTD |
PMID:11172467 PMID:18154422 PMID:24534255 PMID:24998974 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27131391 PMID:30611723 PMID:35752307 PMID:36529352 PMID:36905866 PMID:38103844 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA] |
CTD |
PMID:26847930 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PRKAA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA] |
CTD |
PMID:26634892 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rab18 |
RAB18, member RAS oncogene family |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
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G |
Rabggta |
Rab geranylgeranyltransferase subunit alpha |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348
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G |
Rabggtb |
Rab geranylgeranyltransferase subunit beta |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of RABGGTB mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases phosphorylation |
ISO |
Oleic Acid results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16027227 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Rheb |
Ras homolog, mTORC1 binding |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
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G |
Rhob |
ras homolog family member B |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of RHOB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein] |
CTD |
PMID:36273635 |
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NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Oleic Acid results in increased phosphorylation of RIPK3 protein necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
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G |
Rock2 |
Rho-associated coiled-coil containing protein kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein |
CTD |
PMID:30547786 |
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NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
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G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
Oleic Acid binds to and results in increased activity of RXRA protein |
CTD |
PMID:16731579 PMID:27131391 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of SCD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA] Oleic Acid results in decreased expression of SCD mRNA [Starch co-treated with Oleic Acid] results in increased expression of SCD1 mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of SCD1 mRNA |
CTD |
PMID:24534255 PMID:26895660 PMID:30547786 PMID:30611723 PMID:36423729 PMID:38092172 PMID:38103844 More...
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scp2 |
sterol carrier protein 2 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of SCP2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] |
CTD |
PMID:11292061 PMID:30547786 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sirt1 |
sirtuin 1 |
increases expression multiple interactions decreases activity |
EXP ISO |
Oleic Acid results in increased expression of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased activity of SIRT1 protein]; NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein] [Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein |
CTD |
PMID:24349266 PMID:25536389 PMID:26854922 |
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt4 |
sirtuin 4 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SIRT4 mRNA |
CTD |
PMID:24349266 |
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NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
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G |
Slc13a1 |
solute carrier family 13 member 1 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 4:52,569,179...52,647,126
Ensembl chr 4:52,569,375...52,647,099
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G |
Slc16a9 |
solute carrier family 16, member 9 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022
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G |
Slc25a11 |
solute carrier family 25 member 11 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SLC25A11 mRNA |
CTD |
PMID:24349266 |
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NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410
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G |
Slc25a20 |
solute carrier family 25 member 20 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of SLC25A20 protein [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC25A20 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:24349266 PMID:30611723 |
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NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a22 |
solute carrier family 25 member 22 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SLC25A22 mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331
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G |
Slc27a1 |
solute carrier family 27 member 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC27A1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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G |
Slc27a2 |
solute carrier family 27 member 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SLC27A2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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G |
Slc27a4 |
solute carrier family 27 member 4 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a2 |
solute carrier family 2 member 2 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of SLC2A2 mRNA [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of SLC2A2 mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of SLC2A2 mRNA] |
CTD |
PMID:12048068 PMID:30547786 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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G |
Smim20 |
small integral membrane protein 20 |
increases expression |
ISO |
Oleic Acid results in increased expression of SMIM20 mRNA |
CTD |
PMID:30524225 |
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NCBI chr14:57,711,304...57,722,681
Ensembl chr14:57,711,307...57,722,681
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G |
Snap23 |
synaptosome associated protein 23 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SNAP23 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
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G |
Socs1 |
suppressor of cytokine signaling 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SOCS2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases secretion decreases expression |
ISO |
Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in decreased secretion of SOD1 protein]; gastrodin inhibits the reaction [Oleic Acid results in decreased expression of SOD1 mRNA] |
CTD |
PMID:26634892 PMID:27996362 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of SOD2 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA |
CTD |
PMID:24349266 PMID:30547786 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of SQSTM1 protein [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein]; necrostatin-1 inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein] |
CTD |
PMID:36273635 PMID:36905866 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression multiple interactions decreases expression |
EXP ISO |
Oleic Acid results in increased expression of SREBF1 mRNA Oleic Acid results in increased expression of SREBF1 mRNA; Oleic Acid results in increased expression of SREBF1 protein [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; sophocarpine inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Dibutyl Phthalate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of SREBF1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 protein] Oleic Acid results in decreased expression of SREBF1 mRNA; Oleic Acid results in decreased expression of SREBF1 protein |
CTD |
PMID:15949695 PMID:23395669 PMID:23603006 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30165350 PMID:30611723 PMID:31730885 PMID:33508418 PMID:36347319 PMID:36529352 PMID:36905866 PMID:38092172 PMID:38103844 More...
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Tbxa2r |
thromboxane A2 receptor |
multiple interactions |
EXP |
Phenolsulfonphthalein inhibits the reaction [Oleic Acid results in increased expression of TBXA2R mRNA] |
CTD |
PMID:11263294 |
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NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
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G |
Tecr |
trans-2,3-enoyl-CoA reductase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of TECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tfrc |
transferrin receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein] |
CTD |
PMID:32976958 |
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NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression |
ISO |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TGFB1 protein] |
CTD |
PMID:32918399 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions decreases expression |
ISO |
Bezafibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA] |
CTD |
PMID:24534255 |
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NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TIMP1 mRNA] |
CTD |
PMID:26187275 PMID:30547786 PMID:32918399 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tnf |
tumor necrosis factor |
decreases response to substance increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased susceptibility to TNF protein Oleic Acid results in increased expression of TNF mRNA; Oleic Acid results in increased expression of TNF protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF protein] |
CTD |
PMID:22683933 PMID:23348005 PMID:26190035 PMID:26634892 PMID:30547786 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip2 |
TNF alpha induced protein 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA |
CTD |
PMID:32369900 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tubb2a |
tubulin, beta 2A class IIa |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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G |
Tufm |
Tu translation elongation factor, mitochondrial |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of TUFM mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
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G |
Ucp2 |
uncoupling protein 2 |
increases expression multiple interactions decreases expression |
EXP |
Oleic Acid results in increased expression of UCP2 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of UCP2 protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein] Oleic Acid results in decreased expression of UCP2 mRNA |
CTD |
PMID:11341955 PMID:12588052 PMID:24349266 PMID:25048947 PMID:26854922 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Ucp3 |
uncoupling protein 3 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of UCP3 mRNA Oleic Acid inhibits the reaction [troglitazone results in decreased expression of UCP3 mRNA] |
CTD |
PMID:11056218 PMID:12630940 |
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NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of UGCG mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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G |
Vamp4 |
vesicle-associated membrane protein 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VAMP4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686
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G |
Vcan |
versican |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VCAN mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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G |
Vnn1 |
vanin 1 |
multiple interactions |
ISO |
Oleic Acid promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of VNN1 mRNA] |
CTD |
PMID:31340670 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Yap1 |
Yes1 associated transcriptional regulator |
affects localization |
ISO |
Oleic Acid affects the localization of YAP1 protein |
CTD |
PMID:37117602 |
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NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases export |
ISO |
ABCB1 protein results in increased export of N-oleoylethanolamine |
CTD |
PMID:30102254 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases response to substance multiple interactions |
ISO |
PPARA results in increased susceptibility to N-oleoylethanolamine N-oleoylethanolamine binds to and results in increased activity of PPARA protein |
CTD |
PMID:17906680 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
N-oleoylethanolamine results in decreased expression of PTGS2 protein |
CTD |
PMID:17906680 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases degradation multiple interactions increases phosphorylation |
ISO |
palmitoleic acid results in increased degradation of ABCA1 protein palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] palmitoleic acid results in increased phosphorylation of ABCA1 protein |
CTD |
PMID:16118212 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] |
CTD |
PMID:16118212 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Il6 |
interleukin 6 |
increases expression |
ISO |
palmitoleic acid results in increased expression of IL6 mRNA |
CTD |
PMID:30524225 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of palmitoleic acid analog |
CTD |
PMID:26820058 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
[Glucose deficiency co-treated with palmitoleic acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; palmitoleic acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] palmitoleic acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15375178 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
A2m |
alpha-2-macroglobulin |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of A2M mRNA |
CTD |
PMID:2440878 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]; eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]] |
CTD |
PMID:20438634 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions decreases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] |
CTD |
PMID:11331069 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
decreases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of ABCC1 protein Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC1 protein] |
CTD |
PMID:15517594 PMID:18473823 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein] |
CTD |
PMID:18473823 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ABCC4 mRNA |
CTD |
PMID:19142964 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ACACA mRNA |
CTD |
PMID:37055963 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Ace |
angiotensin I converting enzyme |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein] |
CTD |
PMID:11158990 PMID:15071347 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Aco1 |
aconitase 1 |
multiple interactions increases activity |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein] Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein] |
CTD |
PMID:10889193 |
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NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Actb |
actin, beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA |
CTD |
PMID:15477007 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Adam12 |
ADAM metallopeptidase domain 12 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM12 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
increases response to substance multiple interactions increases expression |
ISO |
ADAM17 results in increased susceptibility to Tetradecanoylphorbol Acetate ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein] Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein] |
CTD |
PMID:12147693 PMID:23774263 PMID:24632454 PMID:26298005 PMID:28703301 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adam8 |
ADAM metallopeptidase domain 8 |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM8 mRNA Tetradecanoylphorbol Acetate results in increased expression of ADAM8 mRNA |
CTD |
PMID:16979875 PMID:19945525 |
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NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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G |
Adm |
adrenomedullin |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of ADM mRNA |
CTD |
PMID:11470465 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Adora2a |
adenosine A2a receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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G |
Adora3 |
adenosine A3 receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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G |
Adra1a |
adrenoceptor alpha 1A |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ADRA1A mRNA |
CTD |
PMID:7900855 |
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NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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G |
Adra1d |
adrenoceptor alpha 1D |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ADRA1D mRNA |
CTD |
PMID:7900855 |
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NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
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G |
Adra2a |
adrenoceptor alpha 2A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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G |
Adrb2 |
adrenoceptor beta 2 |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of ADRB2 protein |
CTD |
PMID:14722251 |
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NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Afp |
alpha-fetoprotein |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP protein |
CTD |
PMID:16368122 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]] |
CTD |
PMID:23541064 |
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA |
CTD |
PMID:19840844 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions affects localization increases expression decreases expression affects response to substance |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of AHR mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and affects the localization of AHR protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SAA3 mRNA]]; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein] Tetradecanoylphorbol Acetate affects the localization of AHR protein Tetradecanoylphorbol Acetate results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate results in increased expression of AHR protein [Tetradecanoylphorbol Acetate co-treated with Tetrachlorodibenzodioxin] results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein] Tetradecanoylphorbol Acetate results in decreased expression of AHR protein AHR protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:1313028 PMID:8390902 PMID:8396892 PMID:9415701 PMID:9706865 PMID:20423157 PMID:23291558 PMID:24481452 More...
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Ahrr |
aryl-hydrocarbon receptor repressor |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA Tetradecanoylphorbol Acetate results in increased expression of AHRR mRNA |
CTD |
PMID:11423533 |
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NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
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Akr1b10 |
aldo-keto reductase family 1 member B10 |
multiple interactions decreases expression |
ISO |
[Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 protein |
CTD |
PMID:25463304 PMID:26198647 |
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NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of AKR1C2 mRNA [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of AKR1C21 mRNA |
CTD |
PMID:18353537 PMID:26198647 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of AKT1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein cyclosporin H inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:20172950 PMID:20438634 PMID:20660715 PMID:22465218 PMID:25590691 PMID:25866363 PMID:27432484 PMID:30590137 PMID:34144024 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alas1 |
5'-aminolevulinate synthase 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ALAS mRNA |
CTD |
PMID:15797241 |
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NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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G |
Alb |
albumin |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA] |
CTD |
PMID:24211529 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of ALOX5 protein; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein |
CTD |
PMID:10779545 PMID:11698504 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ANXA1 mRNA |
CTD |
PMID:19945525 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa10 |
annexin A10 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA10 mRNA |
CTD |
PMID:16979875 |
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NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ANXA2 protein |
CTD |
PMID:20045496 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Anxa3 |
annexin A3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
affects expression |
ISO |
Tetradecanoylphorbol Acetate affects the expression of APAF1 protein |
CTD |
PMID:11139146 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions |
ISO |
[ferric chloride co-treated with Tetradecanoylphorbol Acetate] affects the localization of APEX1 protein |
CTD |
PMID:12023366 |
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NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of APEX2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
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G |
Aplp2 |
amyloid beta precursor like protein 2 |
multiple interactions increases secretion |
ISO |
N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of APLP2 protein] |
CTD |
PMID:16279945 |
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NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA] [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] |
CTD |
PMID:20660715 PMID:22643241 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Arf1 |
ADP-ribosylation factor 1 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of ARF1 protein |
CTD |
PMID:10931844 |
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NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434
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G |
Arf6 |
ADP-ribosylation factor 6 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of ARF6 protein |
CTD |
PMID:10931844 PMID:16280360 |
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NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
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G |
Arhgap20 |
Rho GTPase activating protein 20 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ARHGAP20 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739
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G |
Arhgef9 |
Cdc42 guanine nucleotide exchange factor 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARHGEF9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513
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G |
Arl4c |
ADP ribosylation factor like GTPase 4C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARL4C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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G |
Arl6ip5 |
ADP-ribosylation factor like GTPase 6 interacting protein 5 |
multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Tretinoin results in increased expression of ARL6IP5 mRNA] Tetradecanoylphorbol Acetate results in increased expression of ARL6IP5 protein |
CTD |
PMID:16430862 PMID:16468075 |
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NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arpc2 |
actin related protein 2/3 complex, subunit 2 |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] |
CTD |
PMID:15477007 PMID:16027158 |
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NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
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G |
Art3 |
ADP-ribosyltransferase 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
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G |
Asf1a |
anti-silencing function 1A histone chaperone |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ASF1A mRNA |
CTD |
PMID:26198647 |
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NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ASS1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf5 |
activating transcription factor 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ATF5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ATP1B1 mRNA |
CTD |
PMID:11204457 |
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NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions increases activity decreases expression |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA] Tetradecanoylphorbol Acetate results in increased activity of ATP2A2 protein Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 protein |
CTD |
PMID:17003265 PMID:19244478 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp6v1c2 |
ATPase H+ transporting V1 subunit C2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
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G |
Atp7a |
ATPase copper transporting alpha |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein] which results in increased export of Copper; ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA] |
CTD |
PMID:19205902 |
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NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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G |
Atp7b |
ATPase copper transporting beta |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein |
CTD |
PMID:21189263 |
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NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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G |
Aurka |
aurora kinase A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of AURKA mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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G |
Bace1 |
beta-secretase 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] |
CTD |
PMID:23541064 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Bach1 |
BTB domain and CNC homolog 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of BACH1 mRNA |
CTD |
PMID:33268675 |
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NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAD protein |
CTD |
PMID:25446327 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
multiple interactions |
ISO |
BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA]; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] |
CTD |
PMID:20858459 |
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NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BAK1 protein |
CTD |
PMID:11139146 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
ISO EXP |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAX protein; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein] Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BAX protein] [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of BAX protein] |
CTD |
PMID:15748703 PMID:19161993 PMID:22760862 PMID:25446327 PMID:32662567 PMID:36925031 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions increases expression decreases expression |
ISO EXP |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BCL2 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2 mRNA; edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in decreased expression of BCL2 protein] Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of BCL2 protein] [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in decreased expression of BCL2 protein] Tetradecanoylphorbol Acetate results in decreased expression of BCL2 protein |
CTD |
PMID:9295281 PMID:11139146 PMID:15538571 PMID:15748703 PMID:16979875 PMID:19161993 PMID:19631781 PMID:22760862 PMID:24073338 PMID:25446327 PMID:32662567 PMID:36925031 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions increases expression |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2A1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA] |
CTD |
PMID:15477007 PMID:16979875 PMID:20438634 |
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NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BCL2L1 protein [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2L1 mRNA |
CTD |
PMID:11139146 PMID:18958680 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BECN1 protein |
CTD |
PMID:25446327 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions increases expression |
ISO |
CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BGLAP protein] |
CTD |
PMID:37562720 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BHMT mRNA |
CTD |
PMID:16368122 |
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NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Bik |
BCL2-interacting killer |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BIK mRNA |
CTD |
PMID:26198647 |
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NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of BIRC2 protein |
CTD |
PMID:15187025 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions increases expression |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] |
CTD |
PMID:14527959 PMID:24849683 PMID:31068361 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BIRC5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
decreases response to substance |
ISO |
BMI1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:24571310 |
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NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BMP2 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA] |
CTD |
PMID:10910055 PMID:21331654 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bnip3l |
BCL2 interacting protein 3 like |
multiple interactions increases expression |
EXP |
Plicamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNA] |
CTD |
PMID:16291751 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
Brca1 |
BRCA1, DNA repair associated |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BRCA1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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G |
Bsg |
basigin (Ok blood group) |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein] Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA; Tetradecanoylphorbol Acetate results in increased expression of BSG protein |
CTD |
PMID:16860414 PMID:17055343 PMID:18647594 |
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NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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G |
Bst1 |
bone marrow stromal cell antigen 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180
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G |
Btg2 |
BTG anti-proliferation factor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Go 6976] results in increased expression of BTG2 mRNA |
CTD |
PMID:15302583 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BUB1B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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G |
C3h15orf48 |
similar to human chromosome 15 open reading frame 48 |
affects response to substance affects expression |
ISO |
NMES1 affects the susceptibility to Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the expression of NMES1 |
CTD |
PMID:16044405 |
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NCBI chr 3:109,719,952...109,723,505
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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G |
C4a |
complement C4A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
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G |
C4b |
complement C4B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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G |
C5ar1 |
complement C5a receptor 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of C5AR1 protein |
CTD |
PMID:18559098 |
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NCBI chr 1:76,948,622...76,959,826
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G |
Cacna1g |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CALR mRNA |
CTD |
PMID:19031421 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Camk1 |
calcium/calmodulin-dependent protein kinase I |
multiple interactions increases phosphorylation |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein] |
CTD |
PMID:20590612 |
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NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081
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G |
Camk2b |
calcium/calmodulin-dependent protein kinase II beta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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G |
Capn11 |
calpain 11 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN11 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
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G |
Capn6 |
calpain 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CAPN6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr X:107,380,774...107,405,489
Ensembl chr X:107,380,774...107,405,489
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G |
Capn9 |
calpain 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr19:52,549,448...52,586,413
Ensembl chr19:52,549,448...52,586,413
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G |
Car14 |
carbonic anhydrase 14 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CA14 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
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G |
Car3 |
carbonic anhydrase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CAR3 protein |
CTD |
PMID:20045496 |
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NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased cleavage of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA] |
CTD |
PMID:21515303 PMID:22322153 PMID:23430110 PMID:23535185 PMID:24158569 PMID:26091108 More...
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] |
CTD |
PMID:19631781 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of CASP3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; Tetradecanoylphorbol Acetate inhibits the reaction [arsenic trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased activity of CASP3 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in increased activity of CASP3 protein] Tetradecanoylphorbol Acetate results in decreased expression of CASP3 protein |
CTD |
PMID:11139146 PMID:12165276 PMID:14610070 PMID:15538571 PMID:17309078 PMID:19631781 PMID:24073338 PMID:25446327 PMID:32662567 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CASP8 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP8 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] |
CTD |
PMID:12165276 PMID:15477007 PMID:18958680 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP9 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of and results in increased cleavage of CASP9 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein] Tetradecanoylphorbol Acetate results in decreased expression of CASP9 protein |
CTD |
PMID:17309078 PMID:24073338 PMID:25446327 PMID:32662567 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions decreases expression decreases activity |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CAT mRNA; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased oxidation of 1,2-diaminobenzene] Tetradecanoylphorbol Acetate results in decreased expression of CAT protein Tetradecanoylphorbol Acetate results in decreased activity of CAT protein [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of CAT protein; [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAT protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; CAT inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]; Tetradecanoylphorbol Acetate inhibits the reaction [Patulin results in decreased activity of CAT protein] |
CTD |
PMID:2126186 PMID:3030588 PMID:11243714 PMID:12065085 PMID:12504893 PMID:14997284 PMID:16091123 PMID:18958680 PMID:19095747 PMID:19161993 PMID:20691676 PMID:21964610 PMID:22036979 PMID:22760862 PMID:22981962 PMID:23399806 PMID:31351099 PMID:32662567 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cblif |
cobalamin binding intrinsic factor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CBLIF mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:208,605,983...208,620,231
Ensembl chr 1:208,605,983...208,620,344
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G |
Cbr1 |
carbonyl reductase 1 |
multiple interactions |
ISO |
CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein] |
CTD |
PMID:25818598 |
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NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCL1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL11 protein; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein] |
CTD |
PMID:17572062 PMID:17685462 PMID:21331654 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression increases secretion |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL2 protein; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CCL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein] Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein] |
CTD |
PMID:16376386 PMID:17572062 PMID:17685462 PMID:19063610 PMID:19945525 PMID:20438634 PMID:21035309 PMID:30254419 PMID:30696844 PMID:31217279 PMID:31351099 PMID:31904401 PMID:36416909 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCL20 mRNA |
CTD |
PMID:19945525 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] |
CTD |
PMID:15477007 PMID:17572062 PMID:17685462 PMID:36416909 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL4 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL4 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein] decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL4 protein] |
CTD |
PMID:9122163 PMID:17572062 PMID:17685462 PMID:18958680 PMID:31351099 |
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL5 mRNA |
CTD |
PMID:17572062 PMID:17685462 PMID:31904401 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCN1 mRNA] |
CTD |
PMID:15117851 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna2 |
cyclin A2 |
multiple interactions increases expression decreases expression |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein] Tetradecanoylphorbol Acetate results in increased expression of CCNA2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein Tetradecanoylphorbol Acetate results in decreased expression of CCNA2 protein |
CTD |
PMID:12421932 PMID:15949478 PMID:19031421 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions increases expression |
ISO |
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA] |
CTD |
PMID:10866668 PMID:19000923 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCNB2 mRNA [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCNB2 mRNA |
CTD |
PMID:16979875 PMID:19031421 |
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NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
multiple interactions increases expression decreases expression |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCND1 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of CCND1 protein] Tetradecanoylphorbol Acetate results in decreased expression of CCND1 protein |
CTD |
PMID:15949478 PMID:16368122 PMID:18922899 PMID:20438634 PMID:21375462 PMID:24073338 PMID:26537528 PMID:32662567 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd3 |
cyclin D3 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein] |
CTD |
PMID:12421932 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions increases expression |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein] |
CTD |
PMID:12421932 PMID:24073338 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccng1 |
cyclin G1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd14 |
CD14 molecule |
multiple interactions increases expression |
ISO |
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein] Tetradecanoylphorbol Acetate results in increased expression of CD14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD14 protein |
CTD |
PMID:16430862 PMID:19135038 PMID:20089671 PMID:26036281 PMID:30218697 PMID:33268675 PMID:34506768 More...
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd200 |
Cd200 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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G |
Cd28 |
Cd28 molecule |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Magnesium Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of CD28 protein |
CTD |
PMID:8662792 PMID:11465111 |
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NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cd302 |
CD302 molecule |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CD302 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045
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G |
Cd34 |
CD34 molecule |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 mRNA; [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 protein Tetradecanoylphorbol Acetate results in increased expression of CD34 protein |
CTD |
PMID:18922899 |
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NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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G |
Cd36 |
CD36 molecule |
decreases expression increases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of CD36 mRNA Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD36 protein tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA] 2-chloro-5-nitrobenzanilide inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; [15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 mRNA; [Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [titanium dioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CD36 protein; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; Dibutyl Phthalate inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [[15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]] |
CTD |
PMID:12664607 PMID:16407258 PMID:16484594 PMID:21315065 PMID:23386263 PMID:24746987 PMID:30218697 PMID:32649966 PMID:34506768 PMID:37055963 More...
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd3e |
CD3 epsilon subunit of T-cell receptor complex |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3E protein] |
CTD |
PMID:2824607 |
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NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
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G |
Cd3g |
CD3 gamma subunit of T-cell receptor complex |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3G protein] |
CTD |
PMID:2824607 |
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NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
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G |
Cd4 |
Cd4 molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:157,668,878...157,695,366
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G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD40 mRNA; Apigenin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; fisetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD40 protein]; Quercetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein] |
CTD |
PMID:16601352 PMID:16979875 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd40lg |
CD40 ligand |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD40LG protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG protein |
CTD |
PMID:11297035 PMID:22851303 |
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NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein; Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] |
CTD |
PMID:9929743 PMID:15477007 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd68 |
Cd68 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD68 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD68 protein |
CTD |
PMID:25128825 PMID:28720485 PMID:31011801 |
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NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cd69 |
Cd69 molecule |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD69 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD69 protein 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein] |
CTD |
PMID:12749906 PMID:17962511 PMID:23134680 PMID:23941771 PMID:26343699 PMID:30171972 PMID:31068361 More...
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NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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Cd80 |
Cd80 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD80 protein |
CTD |
PMID:30218697 |
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NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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Cd83 |
CD83 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD83 mRNA |
CTD |
PMID:31068361 |
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NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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Cd9 |
CD9 molecule |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD9 protein [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD9 mRNA |
CTD |
PMID:10910098 PMID:16979875 PMID:19840844 |
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NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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Cdc20 |
cell division cycle 20 |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDC20 mRNA Tetradecanoylphorbol Acetate results in increased expression of CDC20 mRNA |
CTD |
PMID:16979875 PMID:19031421 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdc25b |
cell division cycle 25B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CDC25B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
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Cdc25c |
cell division cycle 25C |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of CDC25C protein |
CTD |
PMID:21375462 |
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NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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Cdc42 |
cell division cycle 42 |
multiple interactions |
EXP |
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]]; Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone] |
CTD |
PMID:2153673 |
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NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein] |
CTD |
PMID:25656647 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh17 |
cadherin 17 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
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Cdh2 |
cadherin 2 |
multiple interactions increases expression |
ISO |
antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] |
CTD |
PMID:25656647 PMID:28108223 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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Cdh5 |
cadherin 5 |
multiple interactions increases phosphorylation |
ISO |
HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] |
CTD |
PMID:24211779 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions decreases expression increases expression |
ISO |
corosolic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA] |
CTD |
PMID:10866668 PMID:32135139 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk2 |
cyclin dependent kinase 2 |
increases activity increases expression multiple interactions decreases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein Tetradecanoylphorbol Acetate results in increased expression of CDK2 protein Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein] Tetradecanoylphorbol Acetate results in decreased phosphorylation of CDK2 protein |
CTD |
PMID:12421932 PMID:15978937 PMID:24073338 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdk4 |
cyclin-dependent kinase 4 |
decreases expression increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CDK4 mRNA Tetradecanoylphorbol Acetate results in increased expression of CDK4 protein PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA] |
CTD |
PMID:10866668 PMID:15978937 PMID:24073338 |
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NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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Cdk6 |
cyclin-dependent kinase 6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CDK6 protein |
CTD |
PMID:24073338 |
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NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Atrazine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Tetradecanoylphorbol Acetate promotes the reaction [Atrazine results in increased expression of CDKN1A mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter] Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein |
CTD |
PMID:9348195 PMID:10910055 PMID:15735102 PMID:15976015 PMID:15978937 PMID:18223691 PMID:18958680 PMID:19945525 PMID:23715767 PMID:24211529 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in increased expression of CDKN1B protein] Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein] |
CTD |
PMID:12421932 PMID:26537528 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN1C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN2A mRNA [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA |
CTD |
PMID:16368122 PMID:18922899 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
multiple interactions |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN2B protein] |
CTD |
PMID:12421932 |
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NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN2C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of CEBPB protein] Tetradecanoylphorbol Acetate results in decreased expression of CEBPB mRNA |
CTD |
PMID:19282384 PMID:33268675 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cfh |
complement factor H |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CFH mRNA |
CTD |
PMID:31904401 |
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NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
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Cga |
glycoprotein hormones, alpha polypeptide |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of CGA mRNA |
CTD |
PMID:21467749 |
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NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Chat |
choline O-acetyltransferase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CHAT mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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Chek1 |
checkpoint kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CHEK1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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Chrnb1 |
cholinergic receptor nicotinic beta 1 subunit |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
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Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions increases expression increases phosphorylation increases activity |
ISO |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein] 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein; Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] |
CTD |
PMID:10820281 PMID:15498850 PMID:16474181 PMID:21035309 PMID:23899529 PMID:26220752 PMID:31351099 More...
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Cks2 |
CDC28 protein kinase regulatory subunit 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CKS2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr17:13,570,611...13,575,770
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G |
Cldn4 |
claudin 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CLDN4 mRNA |
CTD |
PMID:19945525 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Cln3 |
CLN3 lysosomal/endosomal transmembrane protein, battenin |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
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G |
Clta |
clathrin, light chain A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Cmahp |
cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMAHP mRNA |
CTD |
PMID:16979875 |
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NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
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G |
Cmklr1 |
chemerin chemokine-like receptor 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129
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G |
Cnn1 |
calponin 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CNN1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CNN1 protein |
CTD |
PMID:15380616 |
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NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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G |
Cntn6 |
contactin 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CNTN6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:137,354,886...137,751,712
Ensembl chr 4:137,355,367...137,751,119
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL11A1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of COL1A2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of COL1A2 mRNA [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA |
CTD |
PMID:16979875 PMID:18922899 PMID:19840844 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL2A1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col6a1 |
collagen type VI alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] |
CTD |
PMID:15477007 PMID:19840844 |
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NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Comt |
catechol-O-methyltransferase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA |
CTD |
PMID:15477007 |
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NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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G |
Coro1b |
coronin 1B |
multiple interactions increases phosphorylation affects response to substance |
EXP ISO |
Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CORO1B protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] CORO1B protein modified form affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:16027158 |
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NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
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G |
Cox6a1 |
cytochrome c oxidase subunit 6A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
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G |
Cox8a |
cytochrome c oxidase subunit 8A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:204,402,118...204,404,439
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases phosphorylation increases activity |
ISO |
GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein] [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of CREB1 protein modified form]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter] Tetradecanoylphorbol Acetate results in increased activity of CREB1 protein |
CTD |
PMID:10601319 PMID:18791200 PMID:19282384 PMID:20032081 PMID:21047949 PMID:31068361 PMID:35608139 More...
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter] |
CTD |
PMID:16474181 PMID:19282384 PMID:21047949 |
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NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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G |
Crlf2 |
cytokine receptor-like factor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA] |
CTD |
PMID:29462589 |
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NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642
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G |
Crp |
C-reactive protein |
multiple interactions |
EXP |
CRP protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] |
CTD |
PMID:9767445 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Crtam |
cytotoxic and regulatory T cell molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CRTAM mRNA |
CTD |
PMID:16979875 |
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NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343
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G |
Cry1 |
cryptochrome circadian regulator 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CRY1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CSF2 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF2 mRNA; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein] Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] |
CTD |
PMID:1376361 PMID:11752025 PMID:16979875 PMID:17051331 PMID:17572062 PMID:17685462 More...
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF3 mRNA |
CTD |
PMID:9122163 PMID:16979875 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctbp1 |
C-terminal binding protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] |
CTD |
PMID:24211779 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA |
CTD |
PMID:19840844 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsd |
cathepsin D |
decreases cleavage |
ISO |
Tetradecanoylphorbol Acetate results in decreased cleavage of CTSD protein |
CTD |
PMID:36070022 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsg |
cathepsin G |
increases secretion affects localization |
ISO |
Tetradecanoylphorbol Acetate results in increased secretion of CTSG protein Tetradecanoylphorbol Acetate affects the localization of CTSG protein |
CTD |
PMID:25980585 PMID:34144024 |
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NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
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G |
Ctsh |
cathepsin H |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CTSH mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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G |
Ctsl |
cathepsin L |
multiple interactions decreases cleavage |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA Tetradecanoylphorbol Acetate results in decreased cleavage of CTSL protein |
CTD |
PMID:19840844 PMID:36070022 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Cul5 |
cullin 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CX3CL1 mRNA |
CTD |
PMID:19850645 |
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NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA |
CTD |
PMID:9122163 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions decreases expression |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA] |
CTD |
PMID:22359662 PMID:23519560 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA |
CTD |
PMID:22643241 PMID:23519560 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
multiple interactions decreases expression |
ISO |
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA] |
CTD |
PMID:22359662 |
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NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein |
CTD |
PMID:20852150 PMID:26513295 PMID:31351099 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA] |
CTD |
PMID:9122163 PMID:20172950 PMID:22359662 PMID:26513295 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CXCL6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
multiple interactions decreases expression |
ISO |
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA] |
CTD |
PMID:22359662 |
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NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions increases expression |
ISO |
[Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR1 protein; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA] |
CTD |
PMID:15265017 PMID:21045076 |
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NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
multiple interactions |
ISO |
[Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR2 protein |
CTD |
PMID:15265017 |
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NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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G |
Cyba |
cytochrome b-245 alpha chain |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA] |
CTD |
PMID:11172467 PMID:20523355 PMID:21705328 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions increases activity increases expression |
ISO |
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNA] diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein] |
CTD |
PMID:9794432 PMID:29183754 |
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein] |
CTD |
PMID:15748703 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CYP11A1 protein |
CTD |
PMID:18755854 PMID:18787026 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CYP11B2 mRNA |
CTD |
PMID:15666830 |
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NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases activity |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA] Tetradecanoylphorbol Acetate results in decreased activity of CYP19A1 protein |
CTD |
PMID:10338361 PMID:16357189 |
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NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression decreases expression affects response to substance |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 protein; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1A1 protein results in increased abundance of 2-Methoxyestradiol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 protein; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [benzotriphenylene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]] CYP1A1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:1313028 PMID:1497680 PMID:8242868 PMID:8396892 PMID:9415701 PMID:9706865 PMID:11710520 PMID:11728381 PMID:18078826 PMID:18958680 PMID:22643241 PMID:24481452 More...
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer] Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:1313028 PMID:10620351 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions decreases expression |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of CYP1B1 mRNA chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:9706865 PMID:10037446 PMID:11728381 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] |
CTD |
PMID:20206692 |
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NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
ISO |
Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol] Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein |
CTD |
PMID:8531136 PMID:8798623 PMID:9143349 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:16368122 |
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NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions decreases expression decreases activity |
ISO EXP |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP7B1 mRNA Tetradecanoylphorbol Acetate results in decreased expression of CYP7B1 mRNA Tetradecanoylphorbol Acetate results in decreased activity of CYP7B1 protein |
CTD |
PMID:12029625 PMID:16368122 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Dapk1 |
death associated protein kinase 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DAPK1 mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA |
CTD |
PMID:10910055 PMID:23519560 |
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NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Dapk2 |
death-associated protein kinase 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
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G |
Dct |
dopachrome tautomerase |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA]; trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT protein] |
CTD |
PMID:15892717 |
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NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
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G |
Defb5 |
defensin beta 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein] |
CTD |
PMID:28720485 |
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NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467
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G |
Dio3 |
iodothyronine deiodinase 3 |
increases activity multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein Hydrogen Peroxide promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein] |
CTD |
PMID:16935842 PMID:18420745 |
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NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
affects response to substance |
ISO |
DLK1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:18575777 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DMP1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DNAJB9 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:10652249 |
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NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dner |
delta/notch-like EGF repeat containing |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of DNER mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] |
CTD |
PMID:23775084 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock8 |
dedicator of cytokinesis 8 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474
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G |
Dpyd |
dihydropyrimidine dehydrogenase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DPYD mRNA |
CTD |
PMID:15705907 |
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NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions increases expression |
ISO |
[Fluticasone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DUSP1 mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA] |
CTD |
PMID:15860753 PMID:20858459 PMID:31068361 |
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NCBI chr10:16,680,478...16,683,275
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G |
Dusp13b |
dual specificity phosphatase 13B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DUSP13B mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,533,547...2,575,539
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G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DUSP2 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp22 |
dual specificity phosphatase 22 |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene] |
CTD |
PMID:32135139 |
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NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
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G |
Dusp4 |
dual specificity phosphatase 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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G |
E2f4 |
E2F transcription factor 4 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein] |
CTD |
PMID:20479004 |
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NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806
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G |
Eea1 |
early endosome antigen 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] |
CTD |
PMID:22683840 |
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NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EEF1A1 protein |
CTD |
PMID:20045496 |
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NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
multiple interactions |
ISO |
phorbol 13-acetate 12-myristate inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] and decreases phosphorylation of EEF2 protein in colon cancer cells |
RGD |
PMID:31227218 |
RGD:153298919 |
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of EFEMP1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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G |
Efna4 |
ephrin A4 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EFNA4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
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G |
Egf |
epidermal growth factor |
multiple interactions increases expression |
ISO EXP |
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein] Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein] bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; TAPI-2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein; Zinc inhibits the reaction [Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]] |
CTD |
PMID:6309801 PMID:12947092 PMID:19447859 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases expression increases phosphorylation |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein Tetradecanoylphorbol Acetate results in increased expression of EGFR protein naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] |
CTD |
PMID:6309801 PMID:10516208 PMID:19447859 PMID:20660715 PMID:25866363 PMID:26100520 PMID:26513295 More...
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein] Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter] Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein |
CTD |
PMID:10693946 PMID:10739673 PMID:10779383 PMID:10910055 PMID:15920718 PMID:19945525 PMID:20479004 PMID:23715767 PMID:31068361 More...
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of EGR2 mRNA |
CTD |
PMID:15477007 PMID:31068361 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Egr3 |
early growth response 3 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] |
CTD |
PMID:16091474 |
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NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
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G |
Egr4 |
early growth response 4 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EGR4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF2AK2 protein |
CTD |
PMID:30218697 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EIF4A1 mRNA |
CTD |
PMID:31068361 |
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NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858
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G |
Eif4e |
eukaryotic translation initiation factor 4E |
multiple interactions increases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; CGP 57380 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein] |
CTD |
PMID:9545260 PMID:12781867 |
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NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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G |
Eif4e1b |
eukaryotic translation initiation factor 4E family member 1B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA |
CTD |
PMID:23519560 |
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NCBI chr17:9,831,338...9,856,250
Ensembl chr17:9,832,230...9,835,137
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:12781867 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein] |
CTD |
PMID:12781867 |
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NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
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G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EIF4G2 protein |
CTD |
PMID:18491231 |
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NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EIF5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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G |
Elk1 |
ETS transcription factor ELK1 |
increases activity increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of ELK1 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of ELK1 protein |
CTD |
PMID:18791200 PMID:21375462 |
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NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
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G |
Elmo1 |
engulfment and cell motility 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788
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G |
Eln |
elastin |
multiple interactions decreases expression |
EXP |
[Okadaic Acid co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ELN mRNA Tetradecanoylphorbol Acetate results in decreased expression of ELN mRNA |
CTD |
PMID:8997264 |
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NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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G |
Endog |
endonuclease G |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] affects the localization of ENDOG protein |
CTD |
PMID:17309078 |
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NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein] |
CTD |
PMID:24632381 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Ephb6 |
Eph receptor B6 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 4:70,491,973...70,507,230
Ensembl chr 4:70,491,973...70,507,230
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G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein |
CTD |
PMID:24704207 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions increases expression |
ISO |
PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein] |
CTD |
PMID:20479004 |
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
increases cleavage multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein] |
CTD |
PMID:9685416 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Ereg |
epiregulin |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EREG protein |
CTD |
PMID:15066986 |
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NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases expression decreases expression |
ISO |
Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA] [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 protein; Tetradecanoylphorbol Acetate promotes the reaction [Estradiol results in increased expression of ESR1 protein] Tetradecanoylphorbol Acetate results in decreased expression of ESR1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ESR1 protein |
CTD |
PMID:9706865 PMID:10633228 PMID:16368122 PMID:19340542 PMID:20559769 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions increases expression decreases expression |
ISO |
Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA] |
CTD |
PMID:10633228 PMID:20559769 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
[sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of EZH2 protein |
CTD |
PMID:35364107 |
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NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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G |
F11r |
F11 receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA |
CTD |
PMID:23519560 |
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NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
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G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [F2 protein results in increased uptake of Manganese] |
CTD |
PMID:2125206 |
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NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions increases expression |
ISO |
ochratoxin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of F3 protein |
CTD |
PMID:9974427 PMID:18289624 PMID:25569083 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 mRNA; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 protein |
CTD |
PMID:30218697 PMID:37055963 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA] |
CTD |
PMID:21331654 PMID:23519560 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein; Tamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA] |
CTD |
PMID:20529085 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fau |
FAU ubiquitin like and ribosomal protein S30 fusion |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:203,350,226...203,351,741
Ensembl chr 1:203,350,189...203,351,742
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G |
Fbln7 |
fibulin 7 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FBLN7 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983
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G |
Fen1 |
flap structure-specific endonuclease 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FEN1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
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G |
Fga |
fibrinogen alpha chain |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FGA mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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G |
Fgb |
fibrinogen beta chain |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FGB mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf1 |
fibroblast growth factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Fgf10 |
fibroblast growth factor 10 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
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G |
Fgf16 |
fibroblast growth factor 16 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FGF16 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:70,816,658...70,828,028
Ensembl chr X:70,817,433...70,878,717
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G |
Fgf18 |
fibroblast growth factor 18 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions increases secretion |
EXP ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter] Tetradecanoylphorbol Acetate results in increased secretion of FGF2 protein |
CTD |
PMID:10779383 PMID:11874475 PMID:15654655 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:15654655 PMID:23519560 |
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NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Fgg |
fibrinogen gamma chain |
increases expression |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of FGG mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA] |
CTD |
PMID:20858459 |
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NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
multiple interactions increases expression increases secretion |
ISO |
ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FLT1 protein] |
CTD |
PMID:19205902 PMID:22197494 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Flt3 |
Fms related receptor tyrosine kinase 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
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G |
Fmo5 |
flavin containing dimethylaniline monoxygenase 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FMO5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
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G |
Fn1 |
fibronectin 1 |
multiple interactions increases expression increases secretion |
ISO |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FN1 mRNA; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FN1 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein] |
CTD |
PMID:15086456 PMID:16979875 PMID:24211529 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression increases activity affects localization |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOS mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein] Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOS protein Tetradecanoylphorbol Acetate results in increased activity of FOS protein 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of FOS mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOS mRNA; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] |
CTD |
PMID:1932749 PMID:7564102 PMID:7963561 PMID:8386370 PMID:8631129 PMID:9067545 PMID:9122163 PMID:9242432 PMID:9270009 PMID:9417049 PMID:9580328 PMID:9650640 PMID:10381133 PMID:10484327 PMID:10620351 PMID:10693946 PMID:10739673 PMID:10910055 PMID:11687581 PMID:12782152 PMID:15477007 PMID:15705907 PMID:16116958 PMID:17360982 PMID:17693661 PMID:18551458 PMID:18755854 PMID:19225867 PMID:19282384 PMID:19375915 PMID:19716839 PMID:19945525 PMID:20152819 PMID:20590612 PMID:20599481 PMID:21047949 PMID:21354279 PMID:22561169 PMID:22634262 PMID:25656647 PMID:30133131 PMID:30590137 PMID:30696844 PMID:31068361 PMID:31904401 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOSB mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSB protein [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOSB mRNA |
CTD |
PMID:17148446 PMID:31068361 PMID:31904401 |
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NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOSL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein] Tetradecanoylphorbol Acetate results in increased expression of FOSL1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein |
CTD |
PMID:9122163 PMID:17148446 PMID:18755854 PMID:19000923 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FOSL2 mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] |
CTD |
PMID:15477007 PMID:16979875 PMID:17148446 |
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NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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G |
Foxo3 |
forkhead box O3 |
multiple interactions increases activity decreases phosphorylation |
ISO |
FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2] Tetradecanoylphorbol Acetate results in increased activity of FOXO3 protein Tetradecanoylphorbol Acetate results in decreased phosphorylation of FOXO3 protein |
CTD |
PMID:21705328 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Foxp3 |
forkhead box P3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOXP3 protein |
CTD |
PMID:27865421 |
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NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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G |
Frmd3 |
FERM domain containing 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FRMD3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
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G |
Fscn1 |
fascin actin-bundling protein 1 |
multiple interactions increases expression |
ISO |
FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein] Tetradecanoylphorbol Acetate results in increased expression of FSCN1 mRNA |
CTD |
PMID:22102721 |
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NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
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G |
Fshb |
follicle stimulating hormone subunit beta |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FSHB mRNA |
CTD |
PMID:21467749 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fstl1 |
follistatin-like 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
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G |
Fstl4 |
follistatin-like 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FSTL4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:36,911,422...37,344,545
Ensembl chr10:36,911,420...37,338,588
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G |
Fut4 |
fucosyltransferase 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FUT4 protein |
CTD |
PMID:26036281 |
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NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
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G |
Fxyd6 |
FXYD domain-containing ion transport regulator 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FXYD6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958
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G |
Fyb1 |
FYN binding protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions decreases expression |
ISO |
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein] |
CTD |
PMID:23399806 |
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NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gabra3 |
gamma-aminobutyric acid type A receptor subunit alpha 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr X:150,244,745...150,501,566
Ensembl chr X:150,261,607...150,501,559
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of GABRA4 mRNA Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] |
CTD |
PMID:16091474 |
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NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GADD45A mRNA |
CTD |
PMID:10910055 |
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gas6 |
growth arrest specific 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GAS6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gast |
gastrin |
increases secretion |
EXP |
Tetradecanoylphorbol Acetate results in increased secretion of GAST protein |
CTD |
PMID:19208342 |
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NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions increases activity |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter] Tetradecanoylphorbol Acetate results in increased activity of GATA1 protein |
CTD |
PMID:14623254 |
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NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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G |
Gata2 |
GATA binding protein 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA tellimagrandin I promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA] |
CTD |
PMID:14757314 |
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NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Gata3 |
GATA binding protein 3 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA |
CTD |
PMID:22398747 |
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NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
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G |
Gata4 |
GATA binding protein 4 |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GATA4 protein |
CTD |
PMID:11583584 |
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NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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G |
Gatd1 |
glutamine amidotransferase class 1 domain containing 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GATD1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:196,504,533...196,512,561
Ensembl chr 1:196,504,833...196,512,551
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G |
Gba1 |
glucosylceramidase beta 1 |
multiple interactions |
ISO |
GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] |
CTD |
PMID:24951586 |
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NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
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G |
Gbp3 |
guanylate binding protein 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 2:231,460,032...231,500,266
Ensembl chr 2:231,486,062...231,493,098
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Rosuvastatin Calcium] results in increased expression of GCLC mRNA Tetradecanoylphorbol Acetate results in increased expression of GCLC mRNA |
CTD |
PMID:17200146 PMID:18154958 PMID:26198647 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] |
CTD |
PMID:24632381 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GCNT3 mRNA |
CTD |
PMID:26198647 |
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NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
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G |
Gdf10 |
growth differentiation factor 10 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GDF10 mRNA |
CTD |
PMID:16979875 |
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NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
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G |
Gdf11 |
growth differentiation factor 11 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
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G |
Gdf15 |
growth differentiation factor 15 |
multiple interactions increases expression |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] |
CTD |
PMID:23996089 PMID:30218697 |
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NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gfi1 |
growth factor independent 1 transcriptional repressor |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of GFI1 mRNA |
CTD |
PMID:16888099 |
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NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
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G |
Gfra2 |
GDNF family receptor alpha 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions decreases expression decreases localization increases phosphorylation affects localization increases expression |
ISO EXP |
Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein] Tetradecanoylphorbol Acetate results in decreased expression of GJA1 protein Tetradecanoylphorbol Acetate results in decreased localization of GJA1 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein Tetradecanoylphorbol Acetate results in decreased expression of GJA1 mRNA Tetradecanoylphorbol Acetate affects the localization of GJA1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in decreased activity of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein Tetradecanoylphorbol Acetate results in increased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein modified form [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] |
CTD |
PMID:7586169 PMID:7586191 PMID:8020150 PMID:8068183 PMID:8285856 PMID:8597533 PMID:9797139 PMID:10633228 PMID:10973802 PMID:11532878 PMID:11711124 PMID:15250540 PMID:15685554 PMID:19840844 PMID:20510257 PMID:23978459 PMID:30668803 PMID:35413382 PMID:36925031 More...
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gjb2 |
gap junction protein, beta 2 |
multiple interactions decreases expression increases expression |
ISO EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJB2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJB2 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GJB2 protein Tetradecanoylphorbol Acetate results in increased expression of GJB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJB2 protein |
CTD |
PMID:7586191 PMID:8068183 PMID:8597533 |
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NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
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G |
Gjb5 |
gap junction protein, beta 5 |
multiple interactions decreases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJB5 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GJB5 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GJB5 protein |
CTD |
PMID:7586191 PMID:8597533 |
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NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
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G |
Glra1 |
glycine receptor, alpha 1 |
decreases activity |
EXP |
Tetradecanoylphorbol Acetate results in decreased activity of GLRA1 protein |
CTD |
PMID:7752562 |
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NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
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G |
Gnrhr |
gonadotropin releasing hormone receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GNRHR mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
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G |
Gp1ba |
glycoprotein Ib platelet subunit alpha |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein] |
CTD |
PMID:20523355 |
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NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPAT3 mRNA |
CTD |
PMID:26198647 |
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NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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G |
Gpc4 |
glypican 4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] |
CTD |
PMID:2523799 |
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NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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G |
Gpr3 |
G protein-coupled receptor 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPR3 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590
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G |
Gpr84 |
G protein-coupled receptor 84 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPR84 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPX1 protein |
CTD |
PMID:10432307 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of GPX4 protein Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of GPX4 protein] |
CTD |
PMID:10432307 PMID:35608139 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gria3 |
glutamate ionotropic receptor AMPA type subunit 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096
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G |
Grik5 |
glutamate ionotropic receptor kainate type subunit 5 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
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G |
Grn |
granulin precursor |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GRN mRNA |
CTD |
PMID:16873554 |
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NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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G |
Grp |
gastrin releasing peptide |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [GRP protein modified form results in increased chemical synthesis of Inositol Phosphates] |
CTD |
PMID:18313772 |
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NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
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G |
Grpr |
gastrin releasing peptide receptor |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GRPR protein |
CTD |
PMID:29669290 |
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NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein] |
CTD |
PMID:17993264 |
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NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:17993264 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions increases activity decreases activity decreases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of GSR protein; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP] |
CTD |
PMID:11243714 PMID:12504893 PMID:14997284 PMID:19161993 PMID:20691676 PMID:22036979 PMID:22760862 PMID:23399806 More...
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gsto1 |
glutathione S-transferase omega 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions increases expression decreases expression |
ISO |
beta-lapachone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Emodin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; sanguinarine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter] [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 protein |
CTD |
PMID:14623254 PMID:15313406 PMID:15533597 PMID:19840844 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTT1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Gtf2h4 |
general transcription factor 2H subunit 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GTF2H4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
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G |
Gypa |
glycophorin A |
multiple interactions decreases expression increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; chebulinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] |
CTD |
PMID:14769215 PMID:20523355 |
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NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
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G |
Gzmb |
granzyme B |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein Tetradecanoylphorbol Acetate results in increased expression of GZMB mRNA |
CTD |
PMID:20883105 PMID:30171972 |
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NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Hal |
histidine ammonia lyase |
multiple interactions |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of HAL protein |
CTD |
PMID:20691676 |
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NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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G |
Hars1 |
histidyl-tRNA synthetase 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions increases secretion increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of HBEGF mRNA Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein Tetradecanoylphorbol Acetate results in increased expression of HBEGF mRNA [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] |
CTD |
PMID:10910055 PMID:16979875 PMID:20660715 PMID:28703301 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA |
CTD |
PMID:15477007 PMID:23519560 |
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NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
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G |
Hdac5 |
histone deacetylase 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein] |
CTD |
PMID:19124542 |
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NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
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G |
Hdac9 |
histone deacetylase 9 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HDAC9 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
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G |
Hdc |
histidine decarboxylase |
increases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of HDC protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein; atractylon inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; pyeongwee-san extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein] |
CTD |
PMID:10428506 PMID:27553716 |
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NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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G |
Hebp2 |
heme binding protein 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HEBP2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
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G |
Hells |
helicase, lymphoid specific |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HELLS mRNA |
CTD |
PMID:19000923 |
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NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
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G |
Hgf |
hepatocyte growth factor |
multiple interactions increases expression |
ISO |
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA; Tetradecanoylphorbol Acetate results in increased expression of HGF protein |
CTD |
PMID:15802798 PMID:23519560 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hhip |
Hedgehog-interacting protein |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA |
CTD |
PMID:23519560 |
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NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Dithiothreitol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA] Tetradecanoylphorbol Acetate results in increased expression of HIF1A mRNA alternative form; Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form |
CTD |
PMID:11424089 PMID:12479793 PMID:14695184 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HMGCR mRNA |
CTD |
PMID:12044893 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:12044893 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HMOX1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]] HMOX1 enhancer affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA] |
CTD |
PMID:7538129 PMID:18078826 PMID:18958680 PMID:23288142 PMID:24632381 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
multiple interactions increases expression |
ISO |
Indomethacin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HPGD mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein] |
CTD |
PMID:11237475 PMID:15680906 |
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NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of HRAS mRNA; HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein] Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate co-treated with mezerein] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; [Benzo(a)pyrene co-treated with Tetradecanoylphorbol Acetate] affects the mutagenesis of HRAS gene; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of HRAS protein; [Zidovudine co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA] |
CTD |
PMID:3115617 PMID:9766437 PMID:11241758 PMID:11765016 PMID:17106253 PMID:18922899 PMID:22760862 PMID:24211779 More...
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hrh1 |
histamine receptor H 1 |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRH1 mRNA] |
CTD |
PMID:23333628 |
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NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
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G |
Hrh2 |
histamine receptor H 2 |
multiple interactions |
ISO |
HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] |
CTD |
PMID:19277450 |
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NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
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G |
Hs6st2 |
heparan sulfate 6-O-sulfotransferase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HS6ST2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr X:130,966,547...131,261,629
Ensembl chr X:130,968,385...131,261,492
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases activity increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased activity of HSD11B1 protein Tetradecanoylphorbol Acetate results in increased expression of HSD11B1 mRNA |
CTD |
PMID:16533503 |
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NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
multiple interactions |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of HSPA2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA2 mRNA |
CTD |
PMID:18958680 |
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NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein] |
CTD |
PMID:10652249 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
multiple interactions |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HSPA6 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA6 mRNA |
CTD |
PMID:18958680 PMID:24849683 |
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NCBI chr13:83,273,176...83,274,317
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA9 mRNA |
CTD |
PMID:18958680 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases phosphorylation increases expression |
EXP ISO |
Pentobarbital inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HSPB1 protein] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HSPB1 mRNA Tetradecanoylphorbol Acetate results in increased phosphorylation of HSPB1 protein |
CTD |
PMID:7541446 PMID:10839933 PMID:31904401 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hyi |
hydroxypyruvate isomerase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HYI mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:131,894,575...131,897,709
Ensembl chr 5:131,894,598...131,897,251
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G |
Ibsp |
integrin-binding sialoprotein |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IBSP mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ICAM1 protein; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein] Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein |
CTD |
PMID:10484327 PMID:11164475 PMID:20920494 PMID:30218697 PMID:31351099 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Ier2 |
immediate early response 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IER2 mRNA |
CTD |
PMID:31068361 |
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NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
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G |
Ier3 |
immediate early response 3 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA Tetradecanoylphorbol Acetate results in increased expression of IER3 mRNA |
CTD |
PMID:19840844 PMID:19945525 PMID:31068361 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifi27l2b |
interferon, alpha-inducible protein 27 like 2B |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI27L2A mRNA |
CTD |
PMID:31904401 |
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NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
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G |
Ifi44 |
interferon-induced protein 44 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI44 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
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G |
Ifng |
interferon gamma |
multiple interactions increases expression increases secretion |
ISO EXP |
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [2,4-diaminotoluene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Azathioprine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [Decitabine results in increased expression of PLA2G2A protein]]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA] Tetradecanoylphorbol Acetate results in increased expression of IFNG protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA] 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Estradiol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Resveratrol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] |
CTD |
PMID:1371491 PMID:12411406 PMID:12755381 PMID:12812920 PMID:14623498 PMID:14994387 PMID:15358692 PMID:15379866 PMID:15588918 PMID:16154495 PMID:16374615 PMID:16716911 PMID:17051331 PMID:17475810 PMID:17572062 PMID:17685462 PMID:18541274 PMID:18953428 PMID:19277450 PMID:21569788 PMID:22077062 PMID:22398747 PMID:24603311 PMID:25073960 PMID:26343699 PMID:29594315 PMID:30171972 PMID:31351099 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IGF1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IGF1 mRNA; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:10365914 PMID:16368122 PMID:31904401 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions increases phosphorylation |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] |
CTD |
PMID:26513295 |
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NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions increases expression |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP3 mRNA Tetradecanoylphorbol Acetate results in increased expression of IGFBP3 mRNA |
CTD |
PMID:16368122 PMID:19945525 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP7 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions increases phosphorylation increases activity |
ISO |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein |
CTD |
PMID:16474181 PMID:20584749 PMID:23899529 PMID:26220752 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein] Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein] |
CTD |
PMID:12115659 PMID:31351099 |
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NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il10 |
interleukin 10 |
multiple interactions increases expression increases secretion decreases expression |
ISO EXP |
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; catechol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL10 protein]; quinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein] [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; Genistein affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of IL10 mRNA |
CTD |
PMID:12884291 PMID:15502056 PMID:15588918 PMID:15614042 PMID:16374615 PMID:16716911 PMID:17051331 PMID:17572062 PMID:17685462 PMID:19277450 PMID:20423157 PMID:22398747 PMID:25128825 PMID:27865421 PMID:29777833 More...
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il11 |
interleukin 11 |
multiple interactions increases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA] |
CTD |
PMID:22138297 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
IL12A results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:22359662 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12B mRNA Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] |
CTD |
PMID:15614042 PMID:36416909 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb1 |
interleukin 12 receptor subunit beta 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12RB1 protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA] |
CTD |
PMID:11441113 PMID:21331654 |
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NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
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G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12RB2 protein [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL12RB2 mRNA |
CTD |
PMID:11441113 PMID:16979875 |
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NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
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G |
Il13 |
interleukin 13 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL13 mRNA [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]] [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA] |
CTD |
PMID:10428506 PMID:21331654 PMID:22398747 PMID:26091108 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA; biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Genistein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; hexaconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; T0901317 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; tetraconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; triflumizol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] [Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein |
CTD |
PMID:22289359 PMID:25583575 PMID:26513295 PMID:27783946 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il17ra |
interleukin 17 receptor A |
multiple interactions decreases response to substance |
ISO |
[IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; IL17RA results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:22359662 |
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NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
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G |
Il18r1 |
interleukin 18 receptor 1 |
multiple interactions |
ISO |
[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL18R1 protein |
CTD |
PMID:14994387 |
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NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
ISO |
5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; [sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein]; diacerein inhibits the reaction [[sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1A protein [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA] |
CTD |
PMID:7665919 PMID:8435107 PMID:8702551 PMID:9122163 PMID:11851881 PMID:21045076 PMID:35364107 More...
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases secretion increases expression |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1B mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Poly dA-dT] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL1B protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein] Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1B protein [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] |
CTD |
PMID:9122163 PMID:9584910 PMID:10072544 PMID:12812920 PMID:14623498 PMID:16374615 PMID:16557482 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18958421 PMID:20423157 PMID:20709134 PMID:21035309 PMID:21515303 PMID:21807015 PMID:22322153 PMID:22359662 PMID:22981962 PMID:23253724 PMID:23399806 PMID:23430110 PMID:23535185 PMID:23680697 PMID:24131540 PMID:24158569 PMID:24964617 PMID:25446327 PMID:25818598 PMID:26091108 PMID:29458014 PMID:29508652 PMID:30254419 PMID:31351099 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r1 |
interleukin 1 receptor type 1 |
multiple interactions increases expression |
ISO |
SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA] |
CTD |
PMID:21045076 |
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NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions increases expression |
ISO |
SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA] |
CTD |
PMID:21045076 |
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NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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G |
Il1rap |
interleukin 1 receptor accessory protein |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAP mRNA |
CTD |
PMID:16979875 |
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NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
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G |
Il1rapl2 |
interleukin 1 receptor accessory protein-like 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAPL2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:100,961,509...102,271,753
Ensembl chr X:100,961,812...102,271,753
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL1RL1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions increases expression |
ISO |
NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein] |
CTD |
PMID:10072544 |
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NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
increases secretion multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dexamethasone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [diethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Formaldehyde co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Isoniazid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [isophorone diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mitomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pyrimethamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Warfarin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Alitretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Lenalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; NECAME_02783 protein modified form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter]; norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; SB 203580 inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL2 protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA] 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [bis(tri-n-butyltin)oxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Sodium Dodecyl Sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Dronabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; KN 93 inhibits the reaction [Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein] |
CTD |
PMID:1371491 PMID:7815356 PMID:8658534 PMID:8662742 PMID:9439728 PMID:9571986 PMID:9925799 PMID:11592964 PMID:11809870 PMID:12165276 PMID:12411406 PMID:12421932 PMID:12749906 PMID:12812920 PMID:15379866 PMID:15477007 PMID:15588918 PMID:16055081 PMID:16154495 PMID:16168555 PMID:16241859 PMID:16374615 PMID:16531003 PMID:17051331 PMID:17572062 PMID:17615583 PMID:17630204 PMID:17685462 PMID:18423386 PMID:19277450 PMID:19880376 PMID:21075198 PMID:21511917 PMID:21569788 PMID:22398747 PMID:22561169 PMID:23134680 PMID:23941771 PMID:24603311 PMID:25073960 PMID:25770929 PMID:26343699 PMID:29594315 PMID:29777833 PMID:34051231 More...
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il21 |
interleukin 21 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] |
CTD |
PMID:22077062 |
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NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
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G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions increases expression increases secretion |
ISO EXP |
[Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2RA mRNA; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein]; Sirolimus inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein]; Sirolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2RA protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein] 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; tetrathiomolybdate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2RA protein |
CTD |
PMID:7815356 PMID:8586487 PMID:9766631 PMID:12421932 PMID:12749906 PMID:16979875 PMID:22398747 PMID:23134680 PMID:26343699 PMID:27865421 PMID:30171972 More...
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NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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G |
Il2rb |
interleukin 2 receptor subunit beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
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G |
Il3 |
interleukin 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein] [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL3 mRNA |
CTD |
PMID:1376361 PMID:16979875 |
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NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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G |
Il33 |
interleukin 33 |
multiple interactions increases expression |
ISO |
FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL33 mRNA] |
CTD |
PMID:35717073 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
multiple interactions increases secretion increases expression |
ISO EXP |
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL4 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; Leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein] [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein] [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Toluene 2,4-Diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL4 mRNA |
CTD |
PMID:1371491 PMID:8658534 PMID:9766631 PMID:10428506 PMID:12709020 PMID:12755381 PMID:12884291 PMID:15588918 PMID:16601352 PMID:16979875 PMID:17572062 PMID:17685462 PMID:18325701 PMID:19277450 PMID:21515303 PMID:22398747 PMID:25073960 PMID:26091108 PMID:29777833 More...
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
multiple interactions increases expression increases secretion |
ISO EXP |
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL5 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein] deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein] Tetradecanoylphorbol Acetate results in increased expression of IL5 mRNA |
CTD |
PMID:1371491 PMID:8658534 PMID:12884291 PMID:16116958 PMID:16374615 PMID:17475810 PMID:17572062 PMID:17685462 PMID:18325701 More...
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il5ra |
interleukin 5 receptor subunit alpha |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of IL5RA mRNA |
CTD |
PMID:8049355 |
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NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression increases secretion |
ISO EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL6 protein 3'(R)-O-beta-D-glucopyranosyl-3',4'-dihydroxanthyletin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of IL6 protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with 2-Propanol] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Sodium Dodecyl Sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL6 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; levistolide A inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; tepoxalin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased secretion of IL6 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein] |
CTD |
PMID:7759567 PMID:9122163 PMID:10072544 PMID:10428506 PMID:12884291 PMID:16227999 PMID:16374615 PMID:16484594 PMID:17051331 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18434080 PMID:18958421 PMID:19118619 PMID:19416633 PMID:19665545 PMID:19910455 PMID:20043298 PMID:20423157 PMID:20438634 PMID:20709134 PMID:21515303 PMID:22322153 PMID:22398747 PMID:22643241 PMID:22981962 PMID:22986104 PMID:23399806 PMID:23535185 PMID:23835587 PMID:24131540 PMID:24951586 PMID:24964617 PMID:25128825 PMID:25818598 PMID:29777833 PMID:30254419 PMID:30496664 PMID:30524225 PMID:30696844 PMID:30919561 PMID:31351099 PMID:31904401 PMID:32662567 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6r |
interleukin 6 receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL6R mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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G |
Il9r |
interleukin 9 receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL9R mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990
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G |
Inhbc |
inhibin subunit beta C |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Glucose] results in increased secretion of INS1 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:2523799 PMID:10221768 PMID:17069794 PMID:30761839 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:19840844 PMID:23680697 |
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NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Irak3 |
interleukin-1 receptor-associated kinase 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IRAK3 mRNA [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IRAK3 mRNA |
CTD |
PMID:16979875 PMID:31904401 |
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NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
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G |
Ireb2 |
iron responsive element binding protein 2 |
increases activity multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] |
CTD |
PMID:10889193 |
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NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
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G |
Irf4 |
interferon regulatory factor 4 |
multiple interactions decreases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of IRF4 mRNA |
CTD |
PMID:15477007 PMID:33268675 |
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NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
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G |
Irf8 |
interferon regulatory factor 8 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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G |
Isg15 |
ISG15 ubiquitin-like modifier |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ISG15 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
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G |
Itga2 |
integrin subunit alpha 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ITGA2 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA] |
CTD |
PMID:17669516 PMID:21331654 |
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NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
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G |
Itga2b |
integrin subunit alpha 2b |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] |
CTD |
PMID:10428506 PMID:20523355 |
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NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
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G |
Itga5 |
integrin subunit alpha 5 |
multiple interactions increases expression |
ISO |
Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA] |
CTD |
PMID:24211529 |
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NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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G |
Itga7 |
integrin subunit alpha 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450
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G |
Itgal |
integrin subunit alpha L |
multiple interactions affects localization |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGAL protein] |
CTD |
PMID:20883105 |
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NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
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G |
Itgam |
integrin subunit alpha M |
multiple interactions increases expression increases localization |
ISO EXP |
2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; [salvin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGAM protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA; dimemorfan inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein] PMA increases expression of Itgam protein on neutrophils PMA increases expression of ITGAM protein on monocytes Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein] Tetradecanoylphorbol Acetate results in increased expression of ITGAM mRNA; Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein |
CTD RGD |
PMID:10739673 PMID:11504768 PMID:16430862 PMID:16617325 PMID:18500357 PMID:19135038 PMID:19428933 PMID:21331654 PMID:26330309 PMID:29458014 PMID:30218697 PMID:34506768 PMID:36269090 PMID:8102031 PMID:18617650 More...
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RGD:329901912, RGD:329901662 |
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgax |
integrin subunit alpha X |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGAX mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
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G |
Itgb2 |
integrin subunit beta 2 |
increases expression affects localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; crenatoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] |
CTD |
PMID:16393473 PMID:20883105 |
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NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; tellimagrandin I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] |
CTD |
PMID:10910098 PMID:14757314 PMID:14769215 PMID:20523355 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Itgb6 |
integrin subunit beta 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGB6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
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G |
Itgb8 |
integrin subunit beta 8 |
multiple interactions |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ITGB8 mRNA |
CTD |
PMID:24849683 |
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NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ITPR1 protein alternative form |
CTD |
PMID:24073338 |
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NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
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G |
Ivl |
involucrin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA] |
CTD |
PMID:10866668 PMID:17148446 |
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NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] |
CTD |
PMID:26091108 |
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NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases activity increases phosphorylation multiple interactions increases expression increases localization affects localization |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased activity of JUN protein Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein; [JUN gene mutant form results in increased activity of JUN protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein; [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of JUN protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Thiopental inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein] Tetradecanoylphorbol Acetate results in increased expression of JUN; Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]] Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein; Tetradecanoylphorbol Acetate results in increased expression of JUN protein modified form |
CTD |
PMID:1730747 PMID:1932749 PMID:8219202 PMID:8386370 PMID:9067545 PMID:9122163 PMID:9242432 PMID:9580328 PMID:10381133 PMID:10484327 PMID:10620351 PMID:10693946 PMID:12169099 PMID:15263067 PMID:15477007 PMID:15705907 PMID:15944151 PMID:16116958 PMID:17148446 PMID:17360982 PMID:18551458 PMID:18628248 PMID:18755854 PMID:19000923 PMID:19225867 PMID:19282384 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20172950 PMID:20590612 PMID:20599481 PMID:21047949 PMID:21354279 PMID:22542552 PMID:22561169 PMID:23835587 PMID:25073960 PMID:25463304 PMID:25656647 PMID:26100520 PMID:26513295 PMID:27278863 PMID:28108223 PMID:30133131 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31068361 More...
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein] Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of JUNB mRNA] Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA Tetradecanoylphorbol Acetate results in increased expression of JUNB; Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUNB protein |
CTD |
PMID:1932749 PMID:8631129 PMID:15666830 PMID:15920718 PMID:17148446 PMID:19000923 PMID:19945525 PMID:31068361 More...
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer] Tetradecanoylphorbol Acetate results in increased expression of JUND mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUND protein |
CTD |
PMID:1932749 PMID:10620351 PMID:11507057 PMID:17148446 PMID:18755854 |
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NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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G |
Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
decreases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased activity of KCND3 protein alternative form |
CTD |
PMID:11709419 |
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NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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G |
Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
decreases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased activity of KCNE1 protein |
CTD |
PMID:1655403 |
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NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
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G |
Kcnip2 |
potassium voltage-gated channel interacting protein 2 |
decreases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA] |
CTD |
PMID:16385079 |
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NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
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G |
Kcnj4 |
potassium inwardly-rectifying channel, subfamily J, member 4 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [KCNJ4 protein results in decreased susceptibility to Rotenone] |
CTD |
PMID:18619942 |
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NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
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G |
Kif20a |
kinesin family member 20A |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KIF20A mRNA |
CTD |
PMID:16979875 |
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NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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G |
Kif20b |
kinesin family member 20B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF20B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
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G |
Kif23 |
kinesin family member 23 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF23 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
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Kif2c |
kinesin family member 2C |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF2C mRNA |
CTD |
PMID:19031421 |
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NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
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G |
Klf12 |
KLF transcription factor 12 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KLF12 mRNA |
CTD |
PMID:16979875 |
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NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
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G |
Klf4 |
KLF transcription factor 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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G |
Klf6 |
KLF transcription factor 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Kpnb1 |
karyopherin subunit beta 1 |
increases expression multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of KPNB1 protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] |
CTD |
PMID:16365892 PMID:17615583 |
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NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
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Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein] [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS protein |
CTD |
PMID:15263067 PMID:16368122 |
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NCBI chr 4:178,185,418...178,218,484
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Krt18 |
keratin 18 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNA |
CTD |
PMID:16368122 |
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NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
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Krt8 |
keratin 8 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein |
CTD |
PMID:16368122 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Lama5 |
laminin subunit alpha 5 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
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Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LAMB1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc2 |
laminin subunit gamma 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
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Lck |
LCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] |
CTD |
PMID:8662792 |
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NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
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Lcp1 |
lymphocyte cytosolic protein 1 |
multiple interactions increases phosphorylation |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA; KT 5926 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of LCP1 protein] |
CTD |
PMID:14769871 PMID:15477007 |
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NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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Ldlr |
low density lipoprotein receptor |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LDLR mRNA; Tetradecanoylphorbol Acetate results in increased expression of LDLR protein Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] |
CTD |
PMID:29499335 PMID:31068361 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lef1 |
lymphoid enhancer binding factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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G |
Lgals3 |
galectin 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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G |
Lgals8 |
galectin 8 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of LGALS8 mRNA; [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Vehicle Emissions] results in increased expression of LGALS8 mRNA |
CTD |
PMID:18353537 |
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NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
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G |
Lhb |
luteinizing hormone subunit beta |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA Tetrachlorodibenzodioxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP] |
CTD |
PMID:2153673 PMID:21467749 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lif |
LIF, interleukin 6 family cytokine |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LIF mRNA Tetradecanoylphorbol Acetate results in increased expression of LIF mRNA |
CTD |
PMID:16979875 PMID:26198647 |
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NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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Lmo2 |
LIM domain only 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LMO2 mRNA |
CTD |
PMID:7544155 |
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NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953
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G |
Lmo7 |
LIM domain 7 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LMO7 mRNA |
CTD |
PMID:16979875 |
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NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
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G |
LOC120100584 |
small proline-rich protein 2I-like |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of SPRR2A mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPRR2H mRNA] |
CTD |
PMID:18922899 PMID:32135139 |
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NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA |
CTD |
PMID:19840844 |
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NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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Lpl |
lipoprotein lipase |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LPL protein [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LPL protein [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA |
CTD |
PMID:18435438 PMID:19840844 PMID:30218697 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Lrp1 |
LDL receptor related protein 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of LRP1 protein very low density lipoprotein triglyceride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA] |
CTD |
PMID:15910848 |
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NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
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G |
Ltbp4 |
latent transforming growth factor beta binding protein 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
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G |
Lum |
lumican |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of LUM mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
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G |
Mad1l1 |
mitotic arrest deficient 1 like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MAD1L1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr12:14,320,892...14,630,750
Ensembl chr12:14,320,892...14,630,703
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G |
Mad2l1 |
mitotic arrest deficient 2 like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MAD2L1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
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Madd |
MAP-kinase activating death domain |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of MADD gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of MADD gene] |
CTD |
PMID:32135139 |
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NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
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G |
Magi1 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAGI1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691
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Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein] |
CTD |
PMID:20479004 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions increases activity increases phosphorylation |
ISO |
[2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; MAP2K1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein 3,5,3',4',5'-pentahydroxy-stilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] |
CTD |
PMID:8816498 PMID:11861786 PMID:16945329 PMID:17693661 PMID:18767048 PMID:20479004 More...
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NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions increases phosphorylation |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] |
CTD |
PMID:11861786 PMID:15477007 PMID:20479004 PMID:30218697 |
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NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
multiple interactions |
ISO |
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:15944151 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions |
ISO |
[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; pyrazolanthrone inhibits the reaction [[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate]; SB 203580 inhibits the reaction [[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate] |
CTD |
PMID:27278863 |
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NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
multiple interactions |
ISO |
[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; pyrazolanthrone inhibits the reaction [[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate]; SB 203580 inhibits the reaction [[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate] |
CTD |
PMID:27278863 |
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NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
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G |
Map3k12 |
mitogen activated protein kinase kinase kinase 12 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
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G |
Map3k14 |
mitogen-activated protein kinase kinase kinase 14 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MAP3K14 mRNA |
CTD |
PMID:10910055 |
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NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation increases activity increases expression |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein; [Resveratrol results in decreased activity of MAPK1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; Bee Venoms promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; MAPK1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Acrylonitrile results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of MAPK1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Colforsin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Colforsin results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MAPK1 protein modified form]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] Tetradecanoylphorbol Acetate results in increased expression of MAPK1; Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein |
CTD |
PMID:8616849 PMID:8816498 PMID:9545260 PMID:9728050 PMID:10037446 PMID:10660688 PMID:10874129 PMID:10993886 PMID:11145705 PMID:11195782 PMID:11532878 PMID:11551972 PMID:11583584 PMID:11687581 PMID:11728381 PMID:11861786 PMID:12083801 PMID:12115659 PMID:12720544 PMID:12761878 PMID:12781867 PMID:14511371 PMID:14610070 PMID:14739659 PMID:14975926 PMID:15122579 PMID:15385614 PMID:15477007 PMID:15537826 PMID:15542774 PMID:15654655 PMID:15666830 PMID:15728660 PMID:15944151 PMID:15978937 PMID:16091123 PMID:16099101 PMID:16251475 PMID:16474181 PMID:16838270 PMID:16877402 PMID:17080406 PMID:17306214 PMID:17309078 PMID:17693661 PMID:17767925 PMID:18423386 PMID:18628248 PMID:18647594 PMID:19161993 PMID:19282384 PMID:19375915 PMID:19416633 PMID:19447859 PMID:19804834 PMID:19945525 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20188714 PMID:20381601 PMID:20479004 PMID:20590612 PMID:20599481 PMID:20660715 PMID:20709134 PMID:21107699 PMID:21295103 PMID:21354279 PMID:21375462 PMID:22230296 PMID:22245252 PMID:22353212 PMID:22465218 PMID:22542552 PMID:22561169 PMID:22760862 PMID:23134680 PMID:23253724 PMID:23775084 PMID:24211529 PMID:24632454 PMID:25128825 PMID:25463304 PMID:25540590 PMID:25656647 PMID:25818598 PMID:25866363 PMID:25920576 PMID:26537528 PMID:27432484 PMID:28601556 PMID:28731287 PMID:30133131 PMID:30259628 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31351099 PMID:32510591 PMID:32519806 PMID:34144024 PMID:35608139 PMID:36413041 PMID:37562720 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions increases activity increases phosphorylation |
ISO |
SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein] Tetradecanoylphorbol Acetate results in increased activity of MAPK14 protein Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:12781867 PMID:14610070 PMID:15944151 PMID:15949478 PMID:16838270 PMID:17309078 More...
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation increases activity increases expression |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein; [Resveratrol results in decreased activity of MAPK1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Resveratrol results in decreased activity of MAPK3 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased phosphorylation of MAPK3 protein; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; Bee Venoms promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; MAPK3 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Acrylonitrile results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of MAPK3 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein 1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MAPK3 protein modified form]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] Tetradecanoylphorbol Acetate results in increased expression of MAPK3; Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein |
CTD |
PMID:8616849 PMID:8816498 PMID:9545260 PMID:10037446 PMID:10660688 PMID:10874129 PMID:10993886 PMID:11145705 PMID:11195782 PMID:11532878 PMID:11583584 PMID:11687581 PMID:11728381 PMID:11861786 PMID:12083801 PMID:12115659 PMID:12720544 PMID:12761878 PMID:12781867 PMID:12782152 PMID:14511371 PMID:14610070 PMID:14739659 PMID:14975926 PMID:15122579 PMID:15385614 PMID:15477007 PMID:15537826 PMID:15542774 PMID:15654655 PMID:15666830 PMID:15728660 PMID:15944151 PMID:15978937 PMID:16091123 PMID:16099101 PMID:16251475 PMID:16474181 PMID:16838270 PMID:16877402 PMID:17080406 PMID:17306214 PMID:17309078 PMID:17693661 PMID:17767925 PMID:18423386 PMID:18628248 PMID:18647594 PMID:19161993 PMID:19282384 PMID:19375915 PMID:19416633 PMID:19447859 PMID:19804834 PMID:19945525 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20172950 PMID:20188714 PMID:20381601 PMID:20479004 PMID:20590612 PMID:20599481 PMID:20660715 PMID:20709134 PMID:21107699 PMID:21295103 PMID:21354279 PMID:21375462 PMID:22230296 PMID:22245252 PMID:22353212 PMID:22465218 PMID:22542552 PMID:22561169 PMID:22760862 PMID:23134680 PMID:23253724 PMID:23288142 PMID:23775084 PMID:24632454 PMID:25128825 PMID:25463304 PMID:25540590 PMID:25656647 PMID:25818598 PMID:25866363 PMID:25920576 PMID:26537528 PMID:27432484 PMID:28601556 PMID:28731287 PMID:30133131 PMID:30259628 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31351099 PMID:32510591 PMID:32519806 PMID:34144024 PMID:35608139 PMID:36413041 PMID:37562720 More...
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein] Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:14610070 PMID:16838270 PMID:19447859 PMID:20172950 PMID:20381601 PMID:20599481 PMID:21331654 PMID:21354279 PMID:22353212 PMID:23715767 PMID:25073960 PMID:25496033 PMID:25818598 PMID:30133131 PMID:30259628 More...
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk8ip1 |
mitogen-activated protein kinase 8 interacting protein 1 |
multiple interactions |
EXP |
MAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA] |
CTD |
PMID:11513749 |
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NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO |
Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:16838270 PMID:17693661 PMID:19447859 PMID:20599481 PMID:21354279 PMID:22353212 PMID:22561169 PMID:25496033 PMID:25818598 PMID:30133131 PMID:30259628 More...
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NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mapkapk2 |
MAPK activated protein kinase 2 |
increases activity |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of MAPKAPK2 protein |
CTD |
PMID:9545260 |
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NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA |
CTD |
PMID:19840844 |
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NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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G |
Marcksl1 |
MARCKS-like 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MARCKSL1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
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G |
Mark1 |
microtubule affinity regulating kinase 1 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK1 protein |
CTD |
PMID:30218697 |
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NCBI chr13:96,450,189...96,555,304
Ensembl chr13:96,451,487...96,555,173
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G |
Mark2 |
microtubule affinity regulating kinase 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK2 protein |
CTD |
PMID:30218697 |
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NCBI chr 1:204,461,029...204,526,247
Ensembl chr 1:204,461,030...204,525,652
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G |
Mark3 |
microtubule affinity regulating kinase 3 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK3 protein |
CTD |
PMID:30218697 |
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NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647
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G |
Mbl2 |
mannose binding lectin 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MBL2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:228,016,439...228,024,736
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MCL1 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mcm3 |
minichromosome maintenance complex component 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MCM3 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
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G |
Meox2 |
mesenchyme homeobox 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MEOX2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467
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G |
Mertk |
MER proto-oncogene, tyrosine kinase |
increases cleavage |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of MERTK protein |
CTD |
PMID:17047157 |
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NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
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G |
Mest |
mesoderm specific transcript |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MEST mRNA |
CTD |
PMID:31904401 |
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NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions |
ISO |
MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MGMT mRNA |
CTD |
PMID:12663516 PMID:31904401 |
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NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mif |
macrophage migration inhibitory factor |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MIF mRNA; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [MIF protein binds to Heparan Sulfate Proteoglycans]]; Tetradecanoylphorbol Acetate inhibits the reaction [MIF protein binds to Heparan Sulfate Proteoglycans] |
CTD |
PMID:9122163 PMID:26852939 |
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NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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G |
Mir125b1 |
microRNA 125b-1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MIR125B1 mRNA |
CTD |
PMID:33268675 |
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NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
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G |
Mir146a |
microRNA 146a |
multiple interactions increases expression |
ISO |
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MIR146A mRNA]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]; MIR146A mRNA affects the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of NFKBIA protein] |
CTD |
PMID:30090394 |
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NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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G |
Mir155 |
microRNA 155 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MIR155 mRNA |
CTD |
PMID:33268675 |
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NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MKI67 protein |
CTD |
PMID:22981962 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mknk1 |
MAPK interacting serine/threonine kinase 1 |
multiple interactions increases phosphorylation increases activity |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein] |
CTD |
PMID:9545260 PMID:12781867 |
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NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
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G |
Mme |
membrane metallo-endopeptidase |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of MME protein |
CTD |
PMID:16997790 |
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NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; mibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein |
CTD |
PMID:8798622 PMID:16176868 PMID:20004183 PMID:20858459 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions increases expression |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein |
CTD |
PMID:19656660 PMID:20004183 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp14 |
matrix metallopeptidase 14 |
multiple interactions increases expression |
ISO |
3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein |
CTD |
PMID:20152819 PMID:20599481 PMID:21354279 |
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NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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G |
Mmp2 |
matrix metallopeptidase 2 |
increases expression increases activity multiple interactions increases secretion |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein; Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; oxophenylarsine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP2 protein; tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Vorinostat inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP2 protein] |
CTD |
PMID:10455257 PMID:10569804 PMID:15962302 PMID:17498959 PMID:18155510 PMID:19375915 PMID:20152819 PMID:20590612 PMID:20599481 PMID:27163855 PMID:31545954 More...
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp21 |
matrix metallopeptidase 21 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MMP21 mRNA |
CTD |
PMID:16984259 |
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NCBI chr 1:188,480,186...188,485,855
Ensembl chr 1:188,480,186...188,485,855
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; mibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein |
CTD |
PMID:8798622 PMID:16176868 PMID:20004183 PMID:20858459 |
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp7 |
matrix metallopeptidase 7 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MMP7 mRNA |
CTD |
PMID:8798622 |
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NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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G |
Mmp8 |
matrix metallopeptidase 8 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MMP8 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression increases secretion increases activity |
ISO EXP |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MMP9 mRNA; [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of MMP9 protein; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; TAC 101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine co-treated with kahweol acetate] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with pyrazolanthrone] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Bee Venoms inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Curcumin promotes the reaction [3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Hesperidin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; iron protoporphyrin IX inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; N-2-(4-bromophenyl) ethyl caffeamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Nitrites inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; oxophenylarsine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 promotes the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Sildenafil Citrate promotes the reaction [Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; solithromycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of MMP9 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein; Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein; tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Vorinostat inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Y 27632 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein] |
CTD |
PMID:9848099 PMID:10455257 PMID:10569804 PMID:12745093 PMID:14515793 PMID:14627504 PMID:14700523 PMID:15728660 PMID:15962302 PMID:16574429 PMID:16647178 PMID:17055343 PMID:17498959 PMID:18155510 PMID:18628248 PMID:19205902 PMID:19375915 PMID:19447859 PMID:19804834 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20093109 PMID:20138977 PMID:20152819 PMID:20188714 PMID:20590612 PMID:20599481 PMID:21295103 PMID:21354279 PMID:21454668 PMID:22245252 PMID:22523472 PMID:22595400 PMID:22634262 PMID:22696189 PMID:23253724 PMID:23288142 PMID:23359665 PMID:23519560 PMID:23899529 PMID:24211270 PMID:25656647 PMID:25866363 PMID:26614570 PMID:26807887 PMID:27163855 PMID:28731287 PMID:30133131 PMID:30259628 PMID:30590137 PMID:30696844 PMID:30766661 PMID:31545954 PMID:32519806 PMID:34626302 PMID:35364107 PMID:36413041 More...
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
multiple interactions increases expression increases activity increases secretion |
ISO |
[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; CMI 392 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Potassium Cyanide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased oxidation of 1,2-diaminobenzene] 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 2-(4-hydroxy-3,5-dimethylphenyl)-5-methoxy-3-methylindole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-propanoic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; centipedic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; E 6080 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Mangifera indica extract inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO]; SC 41930 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]; zileuton inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] |
CTD |
PMID:3030588 PMID:7812673 PMID:8113982 PMID:8273558 PMID:10381133 PMID:11529688 PMID:16601795 PMID:16716910 PMID:18670081 PMID:18987595 PMID:22036979 PMID:22906169 PMID:26187476 More...
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mpp1 |
MAGUK p55 scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA |
CTD |
PMID:19840844 |
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G |
Mrc1 |
mannose receptor, C type 1 |
multiple interactions increases expression |
ISO |
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 protein] Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MRC1 protein |
CTD |
PMID:26497364 PMID:32135139 |
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NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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G |
Ms4a2 |
membrane spanning 4-domains A2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MS4A2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MS4A2 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310
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G |
Msln |
mesothelin |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MSLN mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
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G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions increases expression |
ISO |
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MSR1 protein; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]] Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form |
CTD |
PMID:9614211 PMID:16484594 PMID:21315065 PMID:23386263 PMID:24746987 |
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NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
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G |
Mt2A |
metallothionein 2A |
multiple interactions increases response to substance increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MT2A mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MT2 mRNA MT2 results in increased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:9506445 PMID:18958680 PMID:20858459 PMID:31904401 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mtor |
mechanistic target of rapamycin kinase |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of MTOR protein |
CTD |
PMID:31068361 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Muc1 |
mucin 1, cell surface associated |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MUC1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions increases secretion increases expression |
EXP ISO |
resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein] Tetradecanoylphorbol Acetate results in increased secretion of MUC5AC protein Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA; Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein 2''-O-acetyl-polygalacin D2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; deapi-platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein]; deapi-platycodin D promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MUC5AC protein]; platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; platycodin D3 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA] |
CTD |
PMID:22213337 PMID:24290472 PMID:25590691 |
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NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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G |
Mx1 |
MX dynamin like GTPase 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MX1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA; catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]; Glucose affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in decreased expression of MYC mRNA] Tetradecanoylphorbol Acetate results in decreased expression of MYC mRNA Tetradecanoylphorbol Acetate results in increased expression of MYC; Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MYC mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MYC protein; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA] Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA; Tetradecanoylphorbol Acetate results in increased expression of MYC protein |
CTD |
PMID:2558650 PMID:8219202 PMID:10381133 PMID:10739673 PMID:12749906 PMID:15477007 PMID:15949478 PMID:16368122 PMID:17106253 More...
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
MYD88 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; MYD88 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:23680697 |
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NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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G |
Mylk |
myosin light chain kinase |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MYLK mRNA |
CTD |
PMID:23519560 |
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NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
Mzf1 |
myeloid zinc finger 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MZF1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:73,670,522...73,682,885
Ensembl chr 1:73,670,541...73,681,635
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G |
Naa80 |
N(alpha)-acetyltransferase 80, NatH catalytic subunit |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563
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G |
Nap1l3 |
nucleosome assembly protein 1-like 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NAP1L3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:88,347,595...88,350,393
Ensembl chr X:88,347,598...88,350,393
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G |
Ncam1 |
neural cell adhesion molecule 1 |
multiple interactions affects localization |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCAM1 protein] |
CTD |
PMID:20883105 |
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NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
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G |
Ncapg |
non-SMC condensin I complex, subunit G |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NCAPG mRNA |
CTD |
PMID:19031421 |
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NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions increases phosphorylation increases expression affects localization |
ISO |
Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 mRNA]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NCF1 protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein] Tetradecanoylphorbol Acetate results in increased expression of NCF1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein |
CTD |
PMID:7575484 PMID:9794432 PMID:11172467 PMID:11246141 PMID:25980585 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions affects localization |
ISO |
Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] |
CTD |
PMID:11246141 PMID:21705328 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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G |
Nek2 |
NIMA-related kinase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NEK2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
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G |
Nell1 |
neural EGFL like 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of NFATC1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in decreased expression of NFATC1 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of NFATC1 protein; NFATC1 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:21603612 PMID:24244623 |
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NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
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G |
Nfatc2 |
nuclear factor of activated T-cells 2 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein; Acetic Acid inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]; NFATC2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein] [Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of and results in decreased phosphorylation of NFATC2 protein; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein] |
CTD |
PMID:17615583 PMID:21603612 PMID:23941771 |
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NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
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G |
Nfatc3 |
nuclear factor of activated T-cells 3 |
multiple interactions |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA] NFATC3 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:12709020 PMID:21603612 |
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NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
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G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
multiple interactions |
ISO |
NFATC4 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:21603612 |
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NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases activity increases expression |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFE2L2 protein; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of NFE2L2 protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFE2L2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]; Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of NFE2L2 protein Tetradecanoylphorbol Acetate results in increased activity of NFE2L2 protein |
CTD |
PMID:20438634 PMID:24632381 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfib |
nuclear factor I/B |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NFIB mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases activity increases expression affects localization |
ISO EXP |
1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFKB1 mRNA; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein; Anethole Trithione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; Fenretinide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein]; indole-3-carbinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; lonafarnib inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKB1 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]] Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein; Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein modified form [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of NFKB1 protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of NFKB1 protein |
CTD |
PMID:8573121 PMID:9122163 PMID:9973483 PMID:10692565 PMID:14527959 PMID:15090542 PMID:15322087 PMID:15710601 PMID:15811958 PMID:15905586 PMID:16007145 PMID:16230421 PMID:16376386 PMID:17498959 PMID:17767925 PMID:17984113 PMID:19539808 PMID:20858459 PMID:23835587 PMID:30133131 PMID:30919561 PMID:34626302 More...
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases phosphorylation increases expression decreases expression increases phosphorylation affects localization increases degradation |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased degradation of NFKBIA protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of NFKBIA mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased activity of and results in increased localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein]; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; MIR146A mRNA affects the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of NFKBIA protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1B protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in decreased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased degradation of NFKBIA protein]; Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of NFKBIA protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] Tetradecanoylphorbol Acetate results in increased expression of NFKBIA protein Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein |
CTD |
PMID:9434740 PMID:10072544 PMID:12115659 PMID:15330761 PMID:15477007 PMID:15502056 PMID:16174796 PMID:16343552 PMID:16376386 PMID:16474181 PMID:17588137 PMID:17767925 PMID:18551458 PMID:18958680 PMID:19416633 PMID:19665545 PMID:20026373 PMID:20043298 PMID:20152819 PMID:20155627 PMID:20206692 PMID:20438634 PMID:20584749 PMID:20858459 PMID:21354279 PMID:21515303 PMID:22322153 PMID:22542552 PMID:23535185 PMID:23899529 PMID:23941771 PMID:25073960 PMID:25540590 PMID:25590691 PMID:25656647 PMID:25818598 PMID:29462589 PMID:30090394 PMID:30590137 PMID:31068361 PMID:31351099 More...
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions |
ISO |
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein |
CTD |
PMID:20026373 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Nfkbil1 |
NFKB inhibitor like 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NFKBIL1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
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G |
Nfkbiz |
NFKB inhibitor zeta |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NFKBIZ mRNA |
CTD |
PMID:31068361 |
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NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
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G |
Ngf |
nerve growth factor |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in increased expression of NGF protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased expression of NGF protein [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA |
CTD |
PMID:23519560 PMID:24244623 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nkd2 |
NKD inhibitor of WNT signaling pathway 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NKD2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821
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G |
Nkg7 |
natural killer cell granule protein 7 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NLRP3 mRNA |
CTD |
PMID:23937860 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nmi |
N-myc (and STAT) interactor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA |
CTD |
PMID:15477007 |
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NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
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G |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NOLC1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
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G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions increases expression |
ISO |
decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS1 protein] |
CTD |
PMID:31351099 |
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NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression increases activity |
ISO EXP |
[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [ginsenoside Rg3 results in increased expression of NOS2 protein]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein] Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein; [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Hydrolyzable Tannins inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; protocatechuic acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; shogaol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] |
CTD |
PMID:14534150 PMID:14700523 PMID:16647178 PMID:18551458 PMID:18683823 PMID:19539808 PMID:20004183 PMID:20026373 PMID:20043298 PMID:20559769 PMID:23899529 PMID:24304388 PMID:24672638 PMID:25818598 PMID:26187476 PMID:31351099 PMID:32135139 PMID:32662567 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NOS3 protein decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS3 protein] |
CTD |
PMID:31351099 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch3 |
notch receptor 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
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G |
Noxo1 |
NADPH oxidase organizer 1 |
multiple interactions |
ISO |
NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] |
CTD |
PMID:21705328 |
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NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061
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G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of NPHS1 mRNA |
CTD |
PMID:16820792 |
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NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
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G |
Nploc4 |
NPL4 homolog, ubiquitin recognition factor |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NPLOC4 protein |
CTD |
PMID:30218697 |
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NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
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G |
Nppa |
natriuretic peptide A |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA; Tetradecanoylphorbol Acetate results in increased expression of NPPA protein (+)-JQ1 compound inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA protein]; MAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]; Mifepristone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA] |
CTD |
PMID:11470465 PMID:11513749 PMID:16533503 PMID:19244478 PMID:23939492 |
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NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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G |
Npy |
neuropeptide Y |
multiple interactions decreases expression |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]] Tetradecanoylphorbol Acetate results in decreased expression of NPY protein |
CTD |
PMID:10660688 PMID:19912776 |
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NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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G |
Npy1r |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of NPY1R mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 protein] |
CTD |
PMID:16979875 PMID:18752316 PMID:24481452 PMID:24632381 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nqo2 |
N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
multiple interactions decreases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NR0B1 protein binds to STAR promoter] Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 protein |
CTD |
PMID:18787026 PMID:19282384 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NR1H2 mRNA |
CTD |
PMID:31011801 |
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NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NR1H3 mRNA |
CTD |
PMID:31011801 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of NR1I2 protein] |
CTD |
PMID:18473823 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases expression multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of NR3C1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of NR3C1 protein [Fluticasone co-treated with Tetradecanoylphorbol Acetate] affects the localization of NR3C1 protein; Salmeterol Xinafoate promotes the reaction [[Fluticasone co-treated with Tetradecanoylphorbol Acetate] affects the localization of NR3C1 protein] Tetradecanoylphorbol Acetate results in increased expression of NR3C1 mRNA |
CTD |
PMID:15860753 PMID:16533503 PMID:21533367 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of NR3C2 mRNA |
CTD |
PMID:16533503 |
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NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
affects localization increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate affects the localization of NR4A1 protein Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein] Tetradecanoylphorbol Acetate results in increased expression of NR4A1 mRNA [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A1 mRNA |
CTD |
PMID:12376465 PMID:16979875 PMID:18787026 PMID:19282384 PMID:28754437 |
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NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A3 mRNA |
CTD |
PMID:15477007 PMID:16979875 |
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NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
multiple interactions |
ISO |
NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA] |
CTD |
PMID:18787026 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G |
Nr5a2 |
nuclear receptor subfamily 5, group A, member 2 |
multiple interactions |
ISO |
alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA] |
CTD |
PMID:16357189 |
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NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA; U 0126 inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA] |
CTD |
PMID:21047912 |
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NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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G |
Nrxn2 |
neurexin 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NRXN2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297
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G |
Nsg2 |
neuronal vesicle trafficking associated 2 |
increases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene] |
CTD |
PMID:32135139 |
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NCBI chr10:15,601,594...15,661,441
Ensembl chr10:15,601,596...15,661,441
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G |
Ntf3 |
neurotrophin 3 |
multiple interactions increases expression |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [imetit results in increased expression of NTF3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein] Tetradecanoylphorbol Acetate results in increased expression of NTF3 protein |
CTD |
PMID:19854260 PMID:21276809 |
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NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
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G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of NTRK2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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G |
Nts |
neurotensin |
multiple interactions decreases activity |
ISO |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Sucrose promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Go 6976 results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NTS protein results in increased chemical synthesis of Inositol Phosphates]; Tetradecanoylphorbol Acetate inhibits the reaction [Ro 31-8220 results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Staurosporine results in increased activity of NTS protein] |
CTD |
PMID:18313772 |
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NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
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G |
Nup54 |
nucleoporin 54 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NUP54 mRNA |
CTD |
PMID:19000923 |
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NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028
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G |
Nusap1 |
nucleolar and spindle associated protein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NUSAP1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
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G |
Oas2 |
2'-5' oligoadenylate synthetase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OAS2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions increases activity increases expression |
ISO |
pyridaben inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] bullatacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Colchicine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]; Glutathione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; phenethyl isothiocyanate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]; Podophyllotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Sodium Selenite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Vitamin E inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein |
CTD |
PMID:1923905 PMID:2591024 PMID:3098411 PMID:7653998 PMID:9270009 PMID:9834970 PMID:10866668 PMID:11243714 PMID:12065085 PMID:12504893 PMID:12628514 PMID:14997284 PMID:15920718 PMID:19161993 PMID:22760862 PMID:22986104 More...
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NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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Olfml2a |
olfactomedin-like 2A |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OLFML2A mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909
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Olr1 |
oxidized low density lipoprotein receptor 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA] |
CTD |
PMID:23386263 |
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NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
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G |
Olr1523 |
olfactory receptor 1523 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OR4D1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:72,708,272...72,709,213
Ensembl chr10:72,707,063...72,715,311
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Oprm1 |
opioid receptor, mu 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA] |
CTD |
PMID:11901219 PMID:18652891 |
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NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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Otc |
ornithine transcarbamylase |
multiple interactions increases activity |
EXP |
[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]; Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; didemnins inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Gossypol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein] |
CTD |
PMID:3097147 |
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NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
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P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
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P2ry1 |
purinergic receptor P2Y1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of P2RY1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
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P2ry2 |
purinergic receptor P2Y2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium] |
CTD |
PMID:17003265 |
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NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
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Pafah1b1 |
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 |
multiple interactions |
EXP |
PAFAH1B1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Phosphatidylcholines] |
CTD |
PMID:12013527 |
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NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
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G |
Pak3 |
p21 (RAC1) activated kinase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PAK3 mRNA |
CTD |
PMID:19031421 |
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NCBI chr X:107,116,308...107,374,342
Ensembl chr X:107,260,898...107,368,314
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Pak6 |
p21 (RAC1) activated kinase 6 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975
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Papss2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PAPSS2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
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Pard6b |
par-6 family cell polarity regulator beta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:156,790,540...156,811,620
Ensembl chr 3:156,790,540...156,811,622
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Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions affects response to substance increases activity |
ISO |
3-aminobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of PARP1 protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [cholix toxin, Vibrio cholerae results in increased cleavage of PARP1 protein] PARP1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:2120135 PMID:2126186 PMID:16323285 PMID:17309078 PMID:28087840 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Parp2 |
poly (ADP-ribose) polymerase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PARP2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
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Pbk |
PDZ binding kinase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PBK mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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G |
Pcbp2 |
poly(rC) binding protein 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
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G |
Pcdha2 |
protocadherin alpha 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCDHA2 mRNA |
CTD |
PMID:16979875 |
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Ensembl chr18:28,581,225...28,846,211
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Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of PCNA protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]; Masoprocol affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; Tacrolimus affects the reaction [Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]] |
CTD |
PMID:10866668 PMID:19840844 PMID:20043298 PMID:25770929 PMID:32662567 PMID:35364107 More...
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pcolce |
procollagen C-endopeptidase enhancer |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCOLCE mRNA |
CTD |
PMID:16979875 |
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NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
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G |
Pcp4 |
Purkinje cell protein 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PCP4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
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G |
Pdcd4 |
programmed cell death 4 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 mRNA Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein] |
CTD |
PMID:21873647 PMID:26513295 |
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NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
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G |
Pde1b |
phosphodiesterase 1B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDE1B mRNA |
CTD |
PMID:23519560 |
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NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
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G |
Pdgfa |
platelet derived growth factor subunit A |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PDGFA mRNA Ramipril inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PDGFA mRNA] |
CTD |
PMID:10352363 PMID:10428506 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdgfb |
platelet derived growth factor subunit B |
multiple interactions increases expression |
ISO EXP |
Ramipril inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PDGFB mRNA] Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA] |
CTD |
PMID:9650640 PMID:10352363 PMID:10428506 |
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NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA |
CTD |
PMID:19840844 |
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NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PECAM1 protein Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PECAM1 protein] |
CTD |
PMID:29458014 |
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NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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G |
Per1 |
period circadian regulator 1 |
multiple interactions |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA] |
CTD |
PMID:23291558 |
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NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
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Pgr |
progesterone receptor |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of PGR mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of PGR mRNA] |
CTD |
PMID:22643241 |
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NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Phex |
phosphate regulating endopeptidase X-linked |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PHEX mRNA |
CTD |
PMID:19000923 |
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NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
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G |
Phka2 |
phosphorylase kinase regulatory subunit alpha 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PHKA2 mRNA [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PYK protein |
CTD |
PMID:23519560 PMID:30218697 |
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NCBI chr X:34,170,959...34,293,498
Ensembl chr X:34,171,323...34,293,466
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Pik3cd |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CD mRNA |
CTD |
PMID:23519560 |
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NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
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Pik3r5 |
phosphoinositide-3-kinase, regulatory subunit 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PIK3R5 mRNA |
CTD |
PMID:19000923 |
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NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
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Pin1 |
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
multiple interactions |
ISO |
E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:20479004 |
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NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785
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Pla2g2a |
phospholipase A2 group IIA |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] |
CTD |
PMID:18953428 |
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NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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G |
Pla2g4a |
phospholipase A2 group IVA |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of PLA2G4A protein |
CTD |
PMID:10874129 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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Plat |
plasminogen activator, tissue type |
increases secretion increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased secretion of PLAT protein Tetradecanoylphorbol Acetate results in increased expression of PLAT protein |
CTD |
PMID:3119194 PMID:8018658 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plau |
plasminogen activator, urokinase |
multiple interactions increases expression increases secretion |
ISO |
arsenic trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of PLAU protein] Tetradecanoylphorbol Acetate results in increased expression of PLAU protein TAC 101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PLAU protein] |
CTD |
PMID:9848099 PMID:15962302 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Plcb2 |
phospholipase C, beta 2 |
affects localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein] |
CTD |
PMID:9295281 |
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NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
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G |
Plcg2 |
phospholipase C, gamma 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLCG2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
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G |
Pld1 |
phospholipase D1 |
increases activity multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased activity of PLD1 protein toxB protein, Clostridium difficile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PLD1 protein] |
CTD |
PMID:14769825 PMID:15067002 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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G |
Pld2 |
phospholipase D2 |
multiple interactions increases activity |
ISO EXP |
PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein] Tetradecanoylphorbol Acetate results in increased activity of PLD2 protein |
CTD |
PMID:15067002 PMID:18423386 |
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NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
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G |
Plek |
pleckstrin |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of PLEK protein Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
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G |
Plin2 |
perilipin 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLIN2 protein |
CTD |
PMID:30218697 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plk1 |
polo-like kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PLK1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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G |
Plxdc2 |
plexin domain containing 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PLXDC2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr17:79,169,238...79,594,279
Ensembl chr17:79,196,369...79,585,282
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G |
Pnpla4 |
patatin like phospholipase domain containing 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr X:42,313,554...42,318,451
Ensembl chr X:42,305,373...42,318,552
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G |
Pole2 |
DNA polymerase epsilon 2, accessory subunit |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of POLE2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
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G |
Pot1 |
protection of telomeres 1 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in increased expression of POT1 mRNA |
CTD |
PMID:26330309 |
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NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
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G |
Pou2f1 |
POU class 2 homeobox 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of POU2F1 protein |
CTD |
PMID:16241859 |
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NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363
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G |
Pou2f2 |
POU class 2 homeobox 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
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G |
Pou4f3 |
POU class 4 homeobox 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of POU4F3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr18:34,390,205...34,392,797
Ensembl chr18:34,390,205...34,392,797
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions increases expression increases activity |
ISO EXP |
PPARA protein affects the reaction [Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]] Tetradecanoylphorbol Acetate results in increased expression of PPARA mRNA Tetradecanoylphorbol Acetate results in increased activity of PPARA protein |
CTD |
PMID:11701232 PMID:16042408 PMID:17360982 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
multiple interactions increases expression |
ISO |
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA] Tetradecanoylphorbol Acetate results in increased expression of PPARD mRNA |
CTD |
PMID:10866668 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases activity increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of PPARG protein Tetradecanoylphorbol Acetate results in increased expression of PPARG mRNA; Tetradecanoylphorbol Acetate results in increased expression of PPARG protein [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of troglitazone]; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] affects the expression of PPARG mRNA; [Tetradecanoylphorbol Acetate results in increased expression of PPARG] which affects the susceptibility to troglitazone; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; MAP2K1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein] |
CTD |
PMID:12044893 PMID:15707588 PMID:16945329 PMID:21511917 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppbp |
pro-platelet basic protein |
multiple interactions increases expression |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PPBP mRNA Tetradecanoylphorbol Acetate results in increased expression of PPBP protein |
CTD |
PMID:15316029 PMID:23519560 |
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NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PPP1R15A mRNA |
CTD |
PMID:31068361 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Ppp1r1b |
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PPP1R1B mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
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G |
Ppp2ca |
protein phosphatase 2 catalytic subunit alpha |
multiple interactions |
ISO |
PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:23775084 |
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NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
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G |
Ppp2cb |
protein phosphatase 2 catalytic subunit beta |
multiple interactions |
ISO |
PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:23775084 |
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NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
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G |
Prdx2 |
peroxiredoxin 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PRDX2 protein |
CTD |
PMID:20045496 |
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NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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G |
Prex1 |
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PREX1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688
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G |
Prf1 |
perforin 1 |
multiple interactions |
ISO |
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein |
CTD |
PMID:30171972 |
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NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
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G |
Prickle1 |
prickle planar cell polarity protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PRICKLE1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:124,639,142...124,735,027
Ensembl chr 7:124,639,142...124,658,113
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G |
Prkca |
protein kinase C, alpha |
multiple interactions increases expression decreases expression affects localization increases phosphorylation increases activity increases localization decreases phosphorylation |
ISO EXP |
[Ethanol results in increased localization of and results in increased activity of PRKCA protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCA protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased phosphorylation of and results in increased activity of PRKCA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate results in increased activity of and affects the localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased phosphorylation of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCA protein Tetradecanoylphorbol Acetate results in increased expression of PRKCA protein modified form Tetradecanoylphorbol Acetate results in decreased expression of PRKCA protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of PRKCA protein] Tetradecanoylphorbol Acetate results in increased localization of PRKCA protein Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Egtazic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; PRKCA protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate binds to and affects the localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCA protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCA protein |
CTD |
PMID:9852137 PMID:10651808 PMID:10656618 PMID:12590138 PMID:12720544 PMID:14678745 PMID:14736339 PMID:14739659 PMID:14975926 PMID:15330761 PMID:15380616 PMID:15976015 PMID:15978937 PMID:16091123 PMID:16099101 PMID:16343552 PMID:16532021 PMID:17106253 PMID:17171646 PMID:18313772 PMID:19394402 PMID:19447859 PMID:20032081 PMID:20152819 PMID:20172950 PMID:20590612 PMID:21047949 PMID:21354279 PMID:21705328 PMID:22020176 PMID:24672638 PMID:25866363 PMID:29669290 PMID:30133131 PMID:36925031 More...
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NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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G |
Prkcb |
protein kinase C, beta |
multiple interactions decreases expression increases phosphorylation affects localization increases activity decreases phosphorylation |
ISO |
[Ethanol results in increased localization of and results in increased activity of PRKCB protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCB protein]; PRKCB protein affects the reaction [Tetradecanoylphorbol Acetate affects the localization of Zinc]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCB protein] Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein; Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein modified form Tetradecanoylphorbol Acetate affects the localization of PRKCB protein; Tetradecanoylphorbol Acetate affects the localization of PRKCB protein alternative form Tetradecanoylphorbol Acetate results in increased activity of PRKCB protein Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein |
CTD |
PMID:1724372 PMID:9852137 PMID:10651808 PMID:15330761 PMID:15380616 PMID:15976015 PMID:16495082 PMID:18313772 PMID:19447859 PMID:21705328 PMID:24672638 PMID:25866363 More...
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NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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G |
Prkcd |
protein kinase C, delta |
multiple interactions decreases expression affects localization increases activity increases phosphorylation increases localization affects phosphorylation |
ISO EXP |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKCD protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein; bisindolylmaleimide I affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKCD protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCD protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein]; PRKCD protein affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with benz(a)anthracene]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCD protein PRKCD protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCD protein Tetradecanoylphorbol Acetate results in decreased expression of PRKCD protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of and affects the localization of PRKCD protein Tetradecanoylphorbol Acetate results in increased localization of PRKCD protein |
CTD |
PMID:9852137 PMID:10567579 PMID:10656618 PMID:11424089 PMID:12755590 PMID:14678745 PMID:15380616 PMID:15538571 PMID:15707588 PMID:15949478 PMID:15976015 PMID:16361709 PMID:18313772 PMID:18628248 PMID:20599481 PMID:21047949 PMID:21354279 PMID:21705328 PMID:22245252 PMID:22643241 PMID:23288142 PMID:23333628 PMID:23941771 PMID:29669290 PMID:30133131 More...
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NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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G |
Prkce |
protein kinase C, epsilon |
multiple interactions decreases expression affects localization increases activity |
ISO EXP |
PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCE protein Tetradecanoylphorbol Acetate results in decreased expression of PRKCE protein Tetradecanoylphorbol Acetate affects the localization of PRKCE protein [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] which results in decreased expression of PRKCE protein; Tetradecanoylphorbol Acetate results in decreased expression of PRKCE protein PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCE protein Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]; PRKCE protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCE protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCE protein |
CTD |
PMID:11507057 PMID:12003851 PMID:12590138 PMID:14623285 PMID:14975926 PMID:16099101 PMID:16793902 PMID:18313772 PMID:21047949 PMID:21705328 PMID:24496235 More...
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NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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G |
Prkcg |
protein kinase C, gamma |
decreases expression affects localization multiple interactions increases activity |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of PRKCG protein Tetradecanoylphorbol Acetate affects the localization of PRKCG protein naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCG protein] [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] Tetradecanoylphorbol Acetate results in increased activity of PRKCG protein |
CTD |
PMID:14975926 PMID:15707588 PMID:15949478 PMID:18652891 PMID:19447859 PMID:25866363 More...
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NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
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G |
Prkch |
protein kinase C, eta |
increases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein [Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein] inhibits the reaction [Sirolimus results in decreased phosphorylation of RPS6 protein] |
CTD |
PMID:16832347 |
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NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
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G |
Prkci |
protein kinase C, iota |
increases localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased localization of PRKCI protein wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of PRKCI protein] |
CTD |
PMID:21295103 |
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NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
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G |
Prkcq |
protein kinase C, theta |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein] |
CTD |
PMID:16241859 |
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NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
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G |
Prkcz |
protein kinase C, zeta |
affects localization increases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate affects the localization of PRKCZ protein Tetradecanoylphorbol Acetate results in increased expression of PRKCZ protein modified form Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCZ protein |
CTD |
PMID:12590138 PMID:15976015 PMID:16532021 |
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NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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G |
Prkd1 |
protein kinase D1 |
multiple interactions increases phosphorylation affects localization increases expression affects phosphorylation |
ISO EXP |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKD1 protein]; [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein; bisindolylmaleimide I affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKD1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] TPA affects localization of Prkd1 protein in cardiomyocytes PMA increases phosphorylation of Prkd1 protein in neonatal ventricular myocytes Tetradecanoylphorbol Acetate results in increased expression of PRKD1 protein modified form Tetradecanoylphorbol Acetate affects the localization of PRKD1 protein [Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein]; PRKD1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKD1 protein |
CTD RGD |
PMID:9852137 PMID:15380616 PMID:16532021 PMID:19124542 PMID:21047949 PMID:21189263 PMID:21705328 PMID:37562720 PMID:15652511 PMID:16648482 More...
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RGD:288084581, RGD:243065275 |
NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
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G |
Prkd2 |
protein kinase D2 |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein]; kb-NB142-70 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein] |
CTD |
PMID:24634417 PMID:37562720 |
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NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
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G |
Prl |
prolactin |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of PRL mRNA [Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein] |
CTD |
PMID:3097147 PMID:21467749 |
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NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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G |
Procr |
protein C receptor |
multiple interactions increases expression decreases cleavage affects localization |
ISO |
[Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PROCR protein modified form]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PROCR protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of PROCR protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]] Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein] |
CTD |
PMID:23774263 PMID:24632454 PMID:26298005 |
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NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
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G |
Prxl2b |
peroxiredoxin like 2B |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PRXL2B mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:165,462,610...165,465,213
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G |
Psmb10 |
proteasome 20S subunit beta 10 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] |
CTD |
PMID:22398747 |
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NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626
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G |
Psmb8 |
proteasome 20S subunit beta 8 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] |
CTD |
PMID:22398747 |
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NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
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G |
Psmc2 |
proteasome 26S subunit, ATPase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PSMC2 protein |
CTD |
PMID:16343552 |
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NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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G |
Psmc6 |
proteasome 26S subunit, ATPase 6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PSMC6 protein |
CTD |
PMID:16343552 |
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NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
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G |
Ptafr |
platelet-activating factor receptor |
multiple interactions increases phosphorylation |
EXP |
RGS4 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTAFR protein] |
CTD |
PMID:11297424 |
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NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
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G |
Ptger3 |
prostaglandin E receptor 3 |
multiple interactions increases phosphorylation |
EXP |
Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTGER3 protein alternative form] |
CTD |
PMID:15937517 |
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NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of PTGES mRNA |
CTD |
PMID:18922899 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgfr |
prostaglandin F receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTGFR mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:240,731,185...240,766,674
Ensembl chr 2:240,733,375...240,765,650
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PTGS1 |
CTD |
PMID:10381133 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases activity |
ISO EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3-methylquercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; shogaol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased expression of PTGS2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] Tetradecanoylphorbol Acetate results in increased expression of PTGS2; Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein 1,5-bis(2-bromophenyl)penta-1,4-dien-3-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; 1,5-bis(2-bromophenyl)penta-1,4-dien-3-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; 3,4-dihydroxyphenylethanol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of 8-epi-prostaglandin F2alpha; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Thromboxane B2; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTGS2 mRNA; Apigenin affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; BAY 11-7085 inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; BAY 11-7085 inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; beta-ionone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; Gallic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; MAPK1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; MAPK3 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein; tricin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] [Genistein co-treated with Capsaicin] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; midostaurin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] |
CTD |
PMID:8621535 PMID:8989914 PMID:9013627 PMID:9576062 PMID:9705326 PMID:10381133 PMID:10718345 PMID:10783318 PMID:11237475 PMID:11458457 PMID:12872987 PMID:14530214 PMID:14613874 PMID:15122579 PMID:15630167 PMID:15680906 PMID:15843042 PMID:15997105 PMID:16417216 PMID:16474181 PMID:16552572 PMID:16557482 PMID:16870006 PMID:16979875 PMID:17767925 PMID:17944529 PMID:18551458 PMID:18683823 PMID:18958680 PMID:19063610 PMID:19095747 PMID:19416633 PMID:19539808 PMID:19656660 PMID:19723084 PMID:19804834 PMID:20004183 PMID:20026373 PMID:20032081 PMID:20043298 PMID:20155627 PMID:20172950 PMID:20423157 PMID:20584749 PMID:20606309 PMID:20660715 PMID:20709134 PMID:20858459 PMID:21375462 PMID:21511917 PMID:21807015 PMID:22036979 PMID:22353212 PMID:22359662 PMID:22523472 PMID:22542552 PMID:22595400 PMID:22760862 PMID:22981962 PMID:22986104 PMID:23399806 PMID:23835587 PMID:23899529 PMID:24304388 PMID:24337631 PMID:24836925 PMID:25818598 PMID:26100520 PMID:26464283 PMID:26513295 PMID:26537528 PMID:27224899 PMID:28108223 PMID:28709031 PMID:29458014 PMID:31351099 PMID:31506784 PMID:32662567 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Pthlh |
parathyroid hormone-like hormone |
increases secretion |
EXP |
Tetradecanoylphorbol Acetate results in increased secretion of PTHLH protein |
CTD |
PMID:7946399 |
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NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
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G |
Ptk2 |
protein tyrosine kinase 2 |
multiple interactions increases expression increases phosphorylation |
ISO |
[oxophenylarsine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein; [Tetradecanoylphorbol Acetate co-treated with oxotremorine M] results in increased phosphorylation of PTK2 protein; [Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein; [Vanadates co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein; [Wortmannin co-treated with Tetradecanoylphorbol Acetate] inhibits the reaction [oxotremorine M results in increased phosphorylation of PTK2 protein]; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTK2 protein]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein]]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTK2 protein]; oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein] |
CTD |
PMID:10537051 PMID:10569804 PMID:24211529 PMID:28527916 PMID:37562720 |
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NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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G |
Ptk2b |
protein tyrosine kinase 2 beta |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of PTK2B protein |
CTD |
PMID:16877402 |
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NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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G |
Ptn |
pleiotrophin |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA |
CTD |
PMID:19840844 |
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NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
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G |
Ptprn2 |
protein tyrosine phosphatase, receptor type N2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTPRN2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:137,439,572...138,191,575
Ensembl chr 6:137,439,540...138,191,575
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PTTG1 mRNA [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA |
CTD |
PMID:19031421 PMID:19840844 |
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NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Ptx3 |
pentraxin 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTX3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 protein; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] Tetradecanoylphorbol Acetate results in increased expression of RAC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of RAC1 protein; Tetradecanoylphorbol Acetate results in increased expression of RAC1 protein modified form |
CTD |
PMID:18922899 PMID:21705328 PMID:28527916 |
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NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Rac2 |
Rac family small GTPase 2 |
multiple interactions |
ISO |
RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:11145705 |
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NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
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G |
Rack1 |
receptor for activated C kinase 1 |
multiple interactions |
ISO |
1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:12782152 |
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NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
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G |
Rad21 |
RAD21 cohesin complex component |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RAD21 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
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G |
Rad51ap1 |
RAD51 associated protein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RAD51AP1 mRNA |
CTD |
PMID:19000923 PMID:19031421 |
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NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524
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G |
Rad51c |
RAD51 paralog C |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RAD51C mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
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G |
Rad54l |
RAD54 like |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RAD54L mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions increases expression increases activity |
ISO |
[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; cypermethrin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein]; Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] |
CTD |
PMID:14623285 PMID:19161993 PMID:22760862 |
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NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Rara |
retinoic acid receptor, alpha |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with salvin] results in increased expression of RARA protein |
CTD |
PMID:11504768 |
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NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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G |
Rarres1 |
retinoic acid receptor responder 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RARRES1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
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G |
Rasal3 |
RAS protein activator like 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RASAL3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:11,396,090...11,411,465
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G |
Rassf2 |
Ras association domain family member 2 |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of RASSF2 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of RASSF2 gene] |
CTD |
PMID:32135139 |
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NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
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G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions increases phosphorylation increases expression decreases phosphorylation |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein] Tetradecanoylphorbol Acetate results in increased expression of RB1 protein modified form Tetradecanoylphorbol Acetate results in decreased phosphorylation of RB1 protein |
CTD |
PMID:8927716 PMID:9348195 PMID:12421932 PMID:15978937 PMID:16979875 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Rbbp8 |
RB binding protein 8, endonuclease |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RBBP8 mRNA |
CTD |
PMID:19031421 |
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NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
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G |
Rbfox2 |
RNA binding fox-1 homolog 2 |
increases expression |
ISO |
PMA increases expression of RBFOX2 mRNA in monocytes |
RGD |
PMID:29771377 |
RGD:329849002 |
NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691
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G |
Rbpj |
recombination signal binding protein for immunoglobulin kappa J region |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of RBPJ protein |
CTD |
PMID:23134680 |
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NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
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G |
Rbx1 |
ring-box 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RBX1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions affects localization |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of REL mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of REL protein] |
CTD |
PMID:9122163 PMID:15477007 PMID:16376386 |
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NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation increases expression increases localization increases activity affects localization |
ISO EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of RELA protein]; Lipopolysaccharides analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein 1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of and results in increased localization of RELA protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein; [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased activity of and results in increased localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein; Anethole Trithione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; Bee Venoms inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Fenretinide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]; indole-3-carbinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; lonafarnib inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of RELA protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; RELA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of RELA protein; Tetradecanoylphorbol Acetate inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]] Tetradecanoylphorbol Acetate results in increased expression of RELA protein; Tetradecanoylphorbol Acetate results in increased expression of RELA protein modified form resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein] |
CTD |
PMID:8573121 PMID:9973483 PMID:10692565 PMID:14527959 PMID:15090542 PMID:15322087 PMID:15710601 PMID:15811958 PMID:15905586 PMID:16007145 PMID:16174796 PMID:16230421 PMID:16376386 PMID:16474181 PMID:16928326 PMID:17498959 PMID:17588137 PMID:17767925 PMID:17984113 PMID:18551458 PMID:18958421 PMID:19284563 PMID:19375915 PMID:19416633 PMID:19539808 PMID:19665545 PMID:19969058 PMID:20026373 PMID:20043298 PMID:20082219 PMID:20152819 PMID:20155627 PMID:20206692 PMID:20438634 PMID:20590612 PMID:20709134 PMID:20858459 PMID:21354279 PMID:21375462 PMID:21515303 PMID:22213337 PMID:22322153 PMID:22542552 PMID:22595400 PMID:22634262 PMID:22981962 PMID:23399806 PMID:23535185 PMID:23899529 PMID:25446327 PMID:25540590 PMID:25590691 PMID:25656647 PMID:25818598 PMID:26187476 PMID:26220752 PMID:26614570 PMID:28108223 PMID:30133131 PMID:30590137 PMID:31068361 PMID:31351099 PMID:34626302 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Resp18 |
regulated endocrine-specific protein 18 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RESP18 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
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Rfc4 |
replication factor C subunit 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RFC4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
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Rfc5 |
replication factor C subunit 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RFC5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
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G |
Rgcc |
regulator of cell cycle |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGCC mRNA [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RGCC mRNA |
CTD |
PMID:16979875 PMID:31904401 |
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NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
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G |
Rgs11 |
regulator of G-protein signaling 11 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGS11 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060
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Rgs13 |
regulator of G-protein signaling 13 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGS13 mRNA |
CTD |
PMID:16979875 |
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NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648
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Rgs16 |
regulator of G-protein signaling 16 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RGS16 mRNA |
CTD |
PMID:31068361 |
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NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
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G |
Rgs4 |
regulator of G-protein signaling 4 |
multiple interactions |
EXP |
RGS4 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTAFR protein] |
CTD |
PMID:11297424 |
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NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
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G |
Rhbdf2 |
rhomboid 5 homolog 2 |
multiple interactions |
ISO |
RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] |
CTD |
PMID:28703301 |
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NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283
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G |
Rhog |
ras homolog family member G |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:156,618,713...156,630,710
Ensembl chr 1:156,615,349...156,631,257
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G |
Rif1 |
replication timing regulatory factor 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RIF1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
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G |
Rnaset2 |
ribonuclease T2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147
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G |
Rnf187 |
ring finger protein 187 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] |
CTD |
PMID:25851810 |
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NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157
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G |
Rnf4 |
ring finger protein 4 |
multiple interactions |
EXP |
[Tetradecanoylphorbol Acetate co-treated with Colforsin] results in increased expression of RNF4 mRNA |
CTD |
PMID:14749358 |
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NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
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G |
Rock1 |
Rho-associated coiled-coil containing protein kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ROCK1 protein |
CTD |
PMID:24760326 |
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NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
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G |
Rpe65 |
retinoid isomerohydrolase RPE65 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RPE65 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
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G |
Rpl7 |
ribosomal protein L7 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:3,217,184...3,220,192
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Rps11 |
ribosomal protein S11 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874
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G |
Rps20 |
ribosomal protein S20 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475
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Rps6 |
ribosomal protein S6 |
multiple interactions increases phosphorylation |
ISO |
[Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein] inhibits the reaction [Sirolimus results in decreased phosphorylation of RPS6 protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein] |
CTD |
PMID:16832347 PMID:18245498 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6ka1 |
ribosomal protein S6 kinase A1 |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] |
CTD |
PMID:17693661 |
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NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions increases phosphorylation |
ISO |
SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]]; Sodium Salicylate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:10993886 PMID:30696844 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Rspo3 |
R-spondin 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RSPO3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:28,283,914...28,368,661
Ensembl chr 1:28,283,914...28,367,061
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G |
RT1-Da |
RT1 class II, locus Da |
multiple interactions |
EXP |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RT1-DA protein |
CTD |
PMID:9536116 |
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NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
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G |
RT1-DMb |
RT1 class II, locus DMb |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of H2-DMB1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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G |
Rtp4 |
receptor (chemosensory) transporter protein 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RTP4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437
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Runx2 |
RUNX family transcription factor 2 |
multiple interactions increases expression |
ISO |
CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RUNX2 protein] |
CTD |
PMID:37562720 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Rxra |
retinoid X receptor alpha |
decreases degradation decreases localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein Tetradecanoylphorbol Acetate results in decreased localization of RXRA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein] |
CTD |
PMID:12970875 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
S100a4 |
S100 calcium-binding protein A4 |
multiple interactions increases expression |
ISO |
Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A4 mRNA] |
CTD |
PMID:24211529 |
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NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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S100a6 |
S100 calcium binding protein A6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of S100A6 protein |
CTD |
PMID:20045496 PMID:24073338 |
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NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
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S100a8 |
S100 calcium binding protein A8 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA] Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA; Tetradecanoylphorbol Acetate results in increased expression of S100A8 protein |
CTD |
PMID:1733233 PMID:20172950 PMID:22359662 |
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NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9 |
S100 calcium binding protein A9 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA] |
CTD |
PMID:1733233 PMID:20045496 PMID:20172950 PMID:22359662 PMID:24073338 |
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NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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S100b |
S100 calcium binding protein B |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] |
CTD |
PMID:23541064 |
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NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
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G |
Sart1 |
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:202,690,472...202,699,136
Ensembl chr 1:202,690,459...202,699,136
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCD1 mRNA |
CTD |
PMID:37055963 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scly |
selenocysteine lyase |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCLY protein |
CTD |
PMID:30218697 |
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NCBI chr 9:91,890,269...91,910,947
Ensembl chr 9:91,890,306...91,910,941
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G |
Scrn1 |
secernin 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SCRN1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 4:83,632,125...83,694,225
Ensembl chr 4:83,632,131...83,693,852
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G |
Sdc1 |
syndecan 1 |
multiple interactions increases secretion decreases expression |
ISO |
GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC1 protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC1 protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased cleavage of and results in increased secretion of SDC1 protein Tetradecanoylphorbol Acetate results in decreased expression of SDC1 protein alternative form |
CTD |
PMID:19875451 PMID:26852939 |
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NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264
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G |
Sdc4 |
syndecan 4 |
multiple interactions decreases expression |
ISO |
GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC4 protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC4 protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased cleavage of and results in increased secretion of SDC4 protein Tetradecanoylphorbol Acetate results in decreased expression of SDC4 protein alternative form |
CTD |
PMID:19875451 |
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NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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G |
Sec61g |
Sec61 translocon subunit gamma |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA |
CTD |
PMID:19840844 |
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NCBI chr14:90,899,766...90,906,143
Ensembl chr14:90,899,768...90,906,162
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G |
Sele |
selectin E |
multiple interactions increases expression |
ISO |
[Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]; adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein] |
CTD |
PMID:8780174 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Selenop |
selenoprotein P |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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G |
Selenos |
selenoprotein S |
multiple interactions |
ISO |
SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein] |
CTD |
PMID:16227999 |
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NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833
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G |
Sell |
selectin L |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of SELL mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of SELL mRNA] |
CTD |
PMID:21331654 |
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NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
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G |
Sem1 |
SEM1 26S proteasome subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SEM1 mRNA [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of SEM1 mRNA |
CTD |
PMID:18922899 |
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NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:34,671,848...34,692,005
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G |
Serpinb2 |
serpin family B member 2 |
affects expression increases expression affects response to substance |
ISO |
Tetradecanoylphorbol Acetate affects the expression of SERPINB2 Tetradecanoylphorbol Acetate results in increased expression of SERPINB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SERPINB2 protein SERPINB2 affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:8631129 PMID:16044405 PMID:19945525 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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G |
Serpinb9 |
serpin family B member 9 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 protein |
CTD |
PMID:12177049 |
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NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions increases secretion increases expression |
ISO EXP |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 protein Tetradecanoylphorbol Acetate results in increased secretion of SERPINE1 protein Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA] [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of SERPINE1 protein |
CTD |
PMID:12409145 PMID:16368122 PMID:18958680 PMID:35001170 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sf3b4 |
splicing factor 3B subunit 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
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G |
Sfrp1 |
secreted frizzled-related protein 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP2 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SFRP2 mRNA |
CTD |
PMID:23519560 PMID:31904401 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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G |
Sftpb |
surfactant protein B |
increases secretion multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein] |
CTD |
PMID:11704537 PMID:14565945 |
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NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
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G |
Sftpc |
surfactant protein C |
increases secretion multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein] |
CTD |
PMID:11704537 PMID:14565945 |
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NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
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G |
Sftpd |
surfactant protein D |
multiple interactions |
EXP ISO |
[Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD protein [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFTPD mRNA |
CTD |
PMID:9476903 PMID:23519560 |
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NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
multiple interactions increases expression |
EXP ISO |
Tetradecanoylphorbol Acetate promotes the reaction [11-dehydrocorticosterone results in increased expression of SGK1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cortisone results in increased expression of SGK1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of SGK1 mRNA |
CTD |
PMID:16533503 PMID:31068361 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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G |
Shank2 |
SH3 and multiple ankyrin repeat domains 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SHANK2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
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G |
Shc1 |
SHC adaptor protein 1 |
increases expression increases phosphorylation multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased expression of SHC1 mRNA Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form] |
CTD |
PMID:19031421 PMID:19168439 |
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NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
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G |
Siglec5 |
sialic acid binding Ig-like lectin 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SIGLEC6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:93,768,190...93,776,696
Ensembl chr 1:93,768,319...93,776,694
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G |
Sla |
src-like adaptor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
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G |
Slc17a3 |
solute carrier family 17 member 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLC17A3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256
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G |
Slc19a1 |
solute carrier family 19 member 1 |
multiple interactions decreases activity |
EXP |
bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]]; Tetradecanoylphorbol Acetate inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate] Tetradecanoylphorbol Acetate results in decreased activity of SLC19A1 protein |
CTD |
PMID:17482559 |
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NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
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G |
Slc1a1 |
solute carrier family 1 member 1 |
multiple interactions increases activity |
EXP |
[Tetradecanoylphorbol Acetate co-treated with Propofol] inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of SLC1A1 protein]; Caffeine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SLC1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Nicotine results in decreased activity of SLC1A1 protein] |
CTD |
PMID:17382927 PMID:23262392 PMID:23602688 PMID:24355585 |
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NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
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G |
Slc1a5 |
solute carrier family 1 member 5 |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of SLC1A5 protein |
CTD |
PMID:21812036 |
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NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
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G |
Slc2a1 |
solute carrier family 2 member 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SLC2A1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc35f1 |
solute carrier family 35, member F1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLC35F1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr20:32,030,350...32,418,762
Ensembl chr20:32,030,368...32,418,611
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G |
Slc38a3 |
solute carrier family 38, member 3 |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of SLC38A3 protein |
CTD |
PMID:21812036 |
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NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
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G |
Slc3a2 |
solute carrier family 3 member 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc5a6 |
solute carrier family 5 member 6 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [SLC5A6 protein results in increased transport of Biotin] |
CTD |
PMID:15561972 |
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NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SLC6A3 protein; Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] |
CTD |
PMID:22683840 PMID:24101030 |
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NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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G |
Slc6a4 |
solute carrier family 6 member 4 |
multiple interactions decreases activity increases phosphorylation |
EXP |
TPA decreases activity of Slc6a4 protein in synaptosomes, TPA increases phosphorylation of Slc6a4 protein in synaptosomes TPA decreases activity of Slc6a4 protein in cultured neurons |
RGD |
PMID:11113454 PMID:11859926 PMID:12590935 |
RGD:38456013, RGD:38549589, RGD:38549585 |
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SLC7A11 mRNA |
CTD |
PMID:17200146 PMID:26198647 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Slc8a1 |
solute carrier family 8 member A1 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of SLC8A1 mRNA] |
CTD |
PMID:19244478 |
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NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
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G |
Slit3 |
slit guidance ligand 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLIT3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634
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G |
Smad2 |
SMAD family member 2 |
multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form] |
CTD |
PMID:20172950 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases methylation |
ISO |
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of SMAD3 gene] |
CTD |
PMID:32135139 |
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NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Smc4 |
structural maintenance of chromosomes 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SMC4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
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G |
Smpd1 |
sphingomyelin phosphodiesterase 1 |
multiple interactions |
ISO |
SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] |
CTD |
PMID:24951586 |
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NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
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G |
Smpdl3a |
sphingomyelin phosphodiesterase, acid-like 3A |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SMPDL3A mRNA |
CTD |
PMID:31904401 |
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NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567
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G |
Snai1 |
snail family transcriptional repressor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein] |
CTD |
PMID:25656647 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snora33 |
small nucleolar RNA, H/ACA box 33 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORA33 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 1:21,682,603...21,682,729
Ensembl chr 1:21,682,603...21,682,729
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G |
Snora73b |
small nucleolar RNA, H/ACA box 73b |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORA73B mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:144,545,179...144,545,382
Ensembl chr 5:144,545,179...144,545,382
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G |
Snora73bl1 |
small nucleolar RNA, H/ACA box 73B like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORA73B mRNA |
CTD |
PMID:31068361 |
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NCBI chr 8:119,852,783...119,852,985
Ensembl chr 8:119,852,783...119,852,985
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G |
Snord51 |
small nucleolar RNA, C/D box 51 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORD51 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 9:64,581,731...64,581,808
Ensembl chr 9:64,581,731...64,581,808
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SOCS2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions increases expression |
ISO |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOCS3 protein] |
CTD |
PMID:23782265 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases expression increases expression |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Glucose deficiency results in decreased expression of and results in increased degradation of SOD1 protein] [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD1 protein Tetradecanoylphorbol Acetate results in decreased expression of SOD1 protein Tetradecanoylphorbol Acetate results in increased expression of SOD1 protein |
CTD |
PMID:17309078 PMID:20045496 PMID:20831825 PMID:24073338 PMID:31351099 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases expression increases activity increases abundance |
ISO EXP |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOD2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin]; Tetradecanoylphorbol Acetate inhibits the reaction [12-deoxyphorbolphenylacetate-20-acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [thymeleatoxin results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of SOD2 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of SOD2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA] [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD2 protein; SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] [Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species] which results in increased abundance of SOD2 |
CTD |
PMID:7564102 PMID:8037686 PMID:8702551 PMID:9067545 PMID:9434740 PMID:9756418 PMID:9837861 PMID:9852137 PMID:10601319 PMID:10669635 PMID:10769695 PMID:11507057 PMID:12161520 PMID:15330761 PMID:17309078 PMID:18958680 PMID:20831825 PMID:21045076 PMID:21705328 PMID:22429591 PMID:31351099 More...
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sorl1 |
sortilin related receptor 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SORL1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
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G |
Sox17 |
SRY-box transcription factor 17 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOX17 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
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G |
Sp1 |
Sp1 transcription factor |
multiple interactions increases expression increases activity |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of SP1 protein; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter] Tetradecanoylphorbol Acetate results in increased expression of SP1 mRNA Tetradecanoylphorbol Acetate results in increased activity of SP1 protein |
CTD |
PMID:10669635 PMID:15978937 PMID:24244623 PMID:27351882 |
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NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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G |
Sp110 |
SP110 nuclear body protein |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SP110 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:86,200,503...86,225,355
Ensembl chr 9:86,200,503...86,222,670
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G |
Spag5 |
sperm associated antigen 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SPAG5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
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G |
Spi1 |
Spi-1 proto-oncogene |
increases activity |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of SPI1 protein |
CTD |
PMID:18418899 |
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NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions increases expression |
ISO |
[FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SPP1 mRNA; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; PPARA protein affects the reaction [Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA] [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein |
CTD |
PMID:11426586 PMID:16979875 PMID:17360982 PMID:19840844 PMID:31904401 PMID:37562720 More...
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Sprr1a |
small proline-rich protein 1A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SPRR1A mRNA Tetradecanoylphorbol Acetate results in increased expression of SPRR1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of SPRR1A protein |
CTD |
PMID:8617999 PMID:10866668 PMID:11485391 |
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NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
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G |
Sprr1b |
small proline-rich protein 1B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SPRR1B mRNA |
CTD |
PMID:11485391 |
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NCBI chr 2:178,008,844...178,010,742
Ensembl chr 2:178,009,130...178,009,567
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G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SQSTM1 mRNA |
CTD |
PMID:26198647 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions increases phosphorylation increases expression |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]] AG 1879 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein] |
CTD |
PMID:20660715 PMID:26100520 PMID:26513295 PMID:28527916 PMID:34144024 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
increases cleavage multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein dorsomorphin promotes the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein] |
CTD |
PMID:29499335 |
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NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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G |
Srpra |
SRP receptor subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone; [Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKCD protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKCE protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NR0B1 protein binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [[Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAR protein] Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA; Tetradecanoylphorbol Acetate results in increased expression of STAR protein |
CTD |
PMID:18755854 PMID:18787026 PMID:19282384 PMID:21047949 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stat3 |
signal transducer and activator of transcription 3 |
increases phosphorylation affects localization multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein Tetradecanoylphorbol Acetate affects the localization of STAT3 protein [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] Tetradecanoylphorbol Acetate results in increased expression of STAT3 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]; Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]] |
CTD |
PMID:20523355 PMID:22986104 PMID:24496235 PMID:25128825 PMID:26100520 PMID:26513295 PMID:30133131 More...
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Stat5a |
signal transducer and activator of transcription 5A |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein] |
CTD |
PMID:20523355 |
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NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
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G |
Stat6 |
signal transducer and activator of transcription 6 |
multiple interactions |
ISO |
[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein |
CTD |
PMID:26091108 |
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NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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G |
Stk11 |
serine/threonine kinase 11 |
multiple interactions decreases phosphorylation |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein] |
CTD |
PMID:26513295 |
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NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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G |
Stmn1 |
stathmin 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of STMN1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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G |
Sts |
steroid sulfatase |
multiple interactions increases expression |
ISO |
prolinedithiocarbamate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; RELA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; STS protein affects the reaction [Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]]; STS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Estradiol]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of STS protein Tetradecanoylphorbol Acetate results in increased expression of STS mRNA |
CTD |
PMID:26220752 PMID:31217279 |
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NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
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G |
Sumo2 |
small ubiquitin-like modifier 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513
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G |
Syn1 |
synapsin I |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
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G |
Syncrip |
synaptotagmin binding, cytoplasmic RNA interacting protein |
multiple interactions affects localization |
ISO |
Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of SYNCRIP protein] |
CTD |
PMID:19331829 |
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NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515
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G |
Taf15 |
TATA-box binding protein associated factor 15 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TAF15 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949
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G |
Tagln |
transgelin |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TAGLN mRNA |
CTD |
PMID:15380616 |
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NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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G |
Tasp1 |
taspase 1 |
multiple interactions increases methylation |
ISO |
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of TASP1 gene] |
CTD |
PMID:32135139 |
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NCBI chr 3:127,176,416...127,408,039
Ensembl chr 3:127,176,692...127,399,600
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G |
Tat |
tyrosine aminotransferase |
multiple interactions |
EXP |
Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Dexamethasone results in increased activity of TAT protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Dexamethasone results in increased activity of TAT protein] |
CTD |
PMID:9398635 |
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NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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G |
Tbx21 |
T-box transcription factor 21 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA] |
CTD |
PMID:22398747 |
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NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
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G |
Terf1 |
telomeric repeat binding factor 1 |
multiple interactions |
ISO |
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA |
CTD |
PMID:26330309 |
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NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
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G |
Terf2 |
telomeric repeat binding factor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TERF2 mRNA 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TERF2 mRNA] |
CTD |
PMID:26330309 |
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NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
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G |
Tert |
telomerase reverse transcriptase |
decreases expression decreases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TERT mRNA Tetradecanoylphorbol Acetate results in decreased activity of TERT protein 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein] |
CTD |
PMID:26330309 |
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NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
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G |
Tfap2a |
transcription factor AP-2 alpha |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [gefitinib inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]] |
CTD |
PMID:21499124 PMID:21951556 |
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NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
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G |
Tff1 |
trefoil factor 1 |
multiple interactions increases expression |
ISO |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein]]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein]]; Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; STS protein affects the reaction [Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein] |
CTD |
PMID:22643241 PMID:31217279 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Tfrc |
transferrin receptor |
multiple interactions decreases expression increases expression |
ISO EXP |
catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein] Tetradecanoylphorbol Acetate results in decreased expression of TFRC protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TFRC protein Tetradecanoylphorbol Acetate results in increased expression of TFRC mRNA |
CTD |
PMID:9766631 PMID:12749906 PMID:19000923 PMID:30218697 |
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NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions increases secretion |
ISO |
ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of TGFA protein |
CTD |
PMID:15066986 PMID:28703301 |
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NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases activity increases expression affects response to substance |
ISO |
[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGFB1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB1 mRNA; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of TGFB1 protein TGFB1 affects the susceptibility to Tetradecanoylphorbol Acetate 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] |
CTD |
PMID:8148055 PMID:10381133 PMID:11728381 PMID:15802798 PMID:16979875 PMID:18434080 PMID:20172950 PMID:20852150 PMID:25128825 PMID:27865421 PMID:30218697 More...
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Tgm1 |
transglutaminase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TGM1 mRNA |
CTD |
PMID:10866668 PMID:11485391 |
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NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
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G |
Tgm2 |
transglutaminase 2 |
multiple interactions decreases expression |
ISO |
Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein] Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein |
CTD |
PMID:22986104 |
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NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
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G |
Th |
tyrosine hydroxylase |
increases expression multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of TH mRNA [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TH protein |
CTD |
PMID:18992715 PMID:24101030 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Thbd |
thrombomodulin |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of THBD mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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G |
Thbs2 |
thrombospondin 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA |
CTD |
PMID:19840844 PMID:23519560 |
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NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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G |
Thpo |
thrombopoietin |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of THPO mRNA |
CTD |
PMID:16979875 |
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Ensembl chr11:80,182,820...80,188,167
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G |
Thy1 |
Thy-1 cell surface antigen |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of THY1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
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G |
Timm17a |
translocase of inner mitochondrial membrane 17A |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TIMM17A mRNA |
CTD |
PMID:16979875 |
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NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA] |
CTD |
PMID:11414687 PMID:18155510 PMID:20599481 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA Tetradecanoylphorbol Acetate results in increased expression of TIMP2 protein |
CTD |
PMID:19840844 PMID:19969058 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Tlr2 |
toll-like receptor 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TLR2 protein |
CTD |
PMID:28720485 |
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NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression |
ISO |
[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; TLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; TLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:23680697 PMID:26187476 PMID:28720485 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tlr6 |
toll-like receptor 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TLR6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
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G |
Tnc |
tenascin C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNC mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression increases secretion affects response to substance |
ISO EXP |
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of TNF protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Glucose co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNF mRNA; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of and results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of TNF protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; butein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in increased secretion of TNF protein]; chromic acid inhibits the reaction [[Glucose co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; chromic chloride inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Doxycycline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Ionomycin inhibits the reaction [[N-(4-hydroxyphenyl)arachidonylamide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; mancozeb inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; NECAME_02783 protein modified form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Ozone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of and results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; tetracycline CMT-3 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; tetracycline CMT-3 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein; TNF affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein] Tetradecanoylphorbol Acetate results in increased expression of TNF; Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA; Tetradecanoylphorbol Acetate results in increased expression of TNF protein TNF protein affects the susceptibility to Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of TNF; Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA; Tetradecanoylphorbol Acetate results in increased expression of TNF protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA] 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; bolinaquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Cannabidiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; centipedic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased expression of and results in increased secretion of TNF protein]]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] |
CTD |
PMID:1371491 PMID:9122163 PMID:9584910 PMID:9628260 PMID:10072544 PMID:10381133 PMID:10769695 PMID:10890505 PMID:11726202 PMID:11851881 PMID:12411406 PMID:12604694 PMID:12812920 PMID:14573775 PMID:14623498 PMID:15358692 PMID:16091123 PMID:16112155 PMID:16134060 PMID:16154495 PMID:16227999 PMID:16557482 PMID:17051331 PMID:17196940 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18434080 PMID:18670081 PMID:18845389 PMID:18958421 PMID:19118619 PMID:19135038 PMID:19277450 PMID:19416633 PMID:19665545 PMID:20043298 PMID:20696233 PMID:20709134 PMID:21035309 PMID:21075198 PMID:21515303 PMID:21807015 PMID:22036979 PMID:22102721 PMID:22322153 PMID:22359662 PMID:22398747 PMID:22981962 PMID:23399806 PMID:23426871 PMID:23535185 PMID:23680697 PMID:24131540 PMID:24964617 PMID:25073960 PMID:25128825 PMID:25446327 PMID:25818598 PMID:27325435 PMID:28087840 PMID:28720485 PMID:29458014 PMID:29777833 PMID:30254419 PMID:30496664 PMID:30796934 PMID:31068361 PMID:31217279 PMID:31351099 PMID:32662567 PMID:33268675 PMID:34051231 PMID:34506768 PMID:36416909 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip3 |
TNF alpha induced protein 3 |
decreases expression multiple interactions increases expression increases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TNFAIP3 mRNA 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TNFAIP3 protein]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]] |
CTD |
PMID:15451058 PMID:20438634 PMID:21035309 PMID:21873647 PMID:31068361 |
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NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions increases expression decreases expression |
ISO |
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; KB R8301 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] Tetradecanoylphorbol Acetate results in decreased expression of TNFRSF1A protein |
CTD |
PMID:9870925 PMID:11882518 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1B protein] |
CTD |
PMID:10072544 PMID:15477007 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tnfrsf21 |
TNF receptor superfamily member 21 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of TNFRSF21 mRNA |
CTD |
PMID:18353537 |
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NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
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G |
Tnfrsf4 |
TNF receptor superfamily member 4 |
multiple interactions increases expression |
EXP |
Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Mercuric Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Staurosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein] |
CTD |
PMID:9766631 |
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NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
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Tnfrsf8 |
TNF receptor superfamily member 8 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TNFRSF8 mRNA |
CTD |
PMID:9933429 |
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NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
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G |
Tnfrsf9 |
TNF receptor superfamily member 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNFRSF9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
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G |
Tnfsf10 |
TNF superfamily member 10 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC1 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC3 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC4 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:21603612 |
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NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tnfsf11 |
TNF superfamily member 11 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TNFSF11 mRNA |
CTD |
PMID:17306214 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Tnfsf8 |
TNF superfamily member 8 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TNFSF8 mRNA |
CTD |
PMID:9933429 |
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NCBI chr 5:77,250,942...77,277,364
Ensembl chr 5:77,251,373...77,277,421
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G |
Tnni3 |
troponin I3, cardiac type |
multiple interactions |
ISO |
chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNI3 protein] |
CTD |
PMID:12003851 |
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NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
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Tnnt2 |
troponin T2, cardiac type |
multiple interactions |
ISO |
chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNT2 protein] |
CTD |
PMID:12003851 |
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NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
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G |
Top2a |
DNA topoisomerase II alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Tp53 |
tumor protein p53 |
decreases expression increases phosphorylation multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of TP53 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein Tetradecanoylphorbol Acetate inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of TP53 protein] |
CTD |
PMID:8076368 PMID:8927716 PMID:10910098 PMID:15542774 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpd52 |
tumor protein D52 |
decreases expression increases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TPD52 mRNA Tetradecanoylphorbol Acetate results in increased expression of TPD52 mRNA |
CTD |
PMID:21873647 |
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NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622
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G |
Tpx2 |
TPX2, microtubule nucleation factor |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TPX2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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G |
Traf1 |
TNF receptor-associated factor 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]] |
CTD |
PMID:15477007 PMID:21035309 |
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NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
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Traf6 |
TNF receptor associated factor 6 |
multiple interactions decreases expression |
ISO |
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA]; hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]] Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein |
CTD |
PMID:30090394 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Trh |
thyrotropin releasing hormone |
multiple interactions |
EXP ISO |
TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein] |
CTD |
PMID:10889193 |
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NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
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G |
Trhde |
thyrotropin-releasing hormone degrading enzyme |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TRHDE mRNA |
CTD |
PMID:16979875 |
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NCBI chr 7:49,943,271...50,350,613
Ensembl chr 7:49,945,766...50,367,371
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G |
Trib2 |
tribbles pseudokinase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370
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G |
Trim7 |
tripartite motif-containing 7 |
multiple interactions |
ISO |
TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] |
CTD |
PMID:25851810 |
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NCBI chr10:33,205,491...33,221,482
Ensembl chr10:33,205,491...33,221,468
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G |
Trnp1 |
TMF1-regulated nuclear protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of TRNP1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:145,706,427...145,713,279
Ensembl chr 5:145,706,094...145,713,272
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G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TRPA1 mRNA |
CTD |
PMID:36847817 |
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NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
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G |
Trpc3 |
transient receptor potential cation channel, subfamily C, member 3 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of TRPC3 mRNA |
CTD |
PMID:19244478 |
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NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases expression increases activity increases localization |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] Tetradecanoylphorbol Acetate results in increased expression of TRPV1 mRNA Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein Tetradecanoylphorbol Acetate results in increased localization of TRPV1 protein bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate affects the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [resiniferatoxin binds to TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lidocaine results in increased activity of TRPV1 protein] RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the activity of TRPV1 protein; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; TRPV1 results in decreased susceptibility to [Capsaicin co-treated with Tetradecanoylphorbol Acetate]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]] |
CTD |
PMID:11140687 PMID:15363968 PMID:16319926 PMID:17913835 PMID:18172555 PMID:19553475 PMID:20660715 PMID:36847817 More...
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Tsc2 |
TSC complex subunit 2 |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of TSC2 protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TSC2 protein] |
CTD |
PMID:15757502 |
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NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
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G |
Tslp |
thymic stromal lymphopoietin |
increases expression multiple interactions increases secretion |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA phorbol 12-myristate 13-acetate increases expression of Tslp protein in keratinocytes Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA; Tetradecanoylphorbol Acetate results in increased expression of TSLP protein FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP protein]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein] [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]; FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein] |
CTD RGD |
PMID:18049884 PMID:24131540 PMID:29462589 PMID:35717073 PMID:29310423 |
RGD:38549374 |
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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G |
Ttc3 |
tetratricopeptide repeat domain 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
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G |
Twf2 |
twinfilin actin-binding protein 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TWF2 protein |
CTD |
PMID:30218697 |
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NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
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G |
Txn1 |
thioredoxin 1 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA Tetradecanoylphorbol Acetate results in increased expression of TXN mRNA |
CTD |
PMID:19840844 PMID:24632381 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TXNRD1 mRNA |
CTD |
PMID:12949356 |
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NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Tymp |
thymidine phosphorylase |
multiple interactions increases expression increases activity |
ISO |
Aspirin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]; TNF affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA] Tetradecanoylphorbol Acetate results in increased activity of TYMP protein |
CTD |
PMID:14573775 |
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NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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G |
Tyms |
thymidylate synthetase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TYMS mRNA |
CTD |
PMID:19031421 |
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NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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G |
Tyr |
tyrosinase |
multiple interactions |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of TYR protein |
CTD |
PMID:20691676 |
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NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
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G |
Tyrobp |
transmembrane immune signaling adaptor Tyrobp |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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G |
Ubc |
ubiquitin C |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
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G |
Uhrf1 |
ubiquitin-like with PHD and ring finger domains 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of UHRF1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of UHRF1 protein |
CTD |
PMID:15964557 |
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NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
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G |
Ulbp1 |
UL16 binding protein 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride results in increased expression of ULBP1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Gefitinib inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [Gefitinib results in increased expression of ULBP1 mRNA] |
CTD |
PMID:21499124 PMID:21951556 |
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NCBI chr 1:1,694,255...1,716,160
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G |
Ulk1 |
unc-51 like autophagy activating kinase 1 |
multiple interactions |
ISO |
[maslinic acid analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of ULK1 protein |
CTD |
PMID:26513295 |
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NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
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G |
Uri1 |
URI1, prefoldin-like chaperone |
increases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene] |
CTD |
PMID:32135139 |
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NCBI chr 1:90,646,392...90,704,811
Ensembl chr 1:90,646,393...90,709,026
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G |
Usp18 |
ubiquitin specific peptidase 18 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of USP18 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of VCAM1 protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of VCAM1 protein] |
CTD |
PMID:12615669 PMID:21035309 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vdr |
vitamin D receptor |
multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein] Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA] Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA; Tetradecanoylphorbol Acetate results in increased expression of VDR protein |
CTD |
PMID:9348195 PMID:11504768 PMID:20006981 |
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NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases secretion increases expression decreases expression |
ISO EXP |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA protein; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein modified form; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of VEGFA mRNA; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of VEGFA protein]; eriodictyol affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA] [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] which results in decreased expression of PRKCE protein; Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] [Norepinephrine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] |
CTD |
PMID:8537383 PMID:9743532 PMID:10788502 PMID:11158990 PMID:11214823 PMID:12590138 PMID:16979875 PMID:19000923 PMID:19063610 PMID:19910455 PMID:20438634 PMID:26513295 More...
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein] [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of VIM protein; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein] |
CTD |
PMID:15477007 PMID:25656647 PMID:28108223 PMID:35364107 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Vipr2 |
vasoactive intestinal peptide receptor 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of VIPR2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597
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G |
Vit |
vitrin |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of VIT mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:16,445,966...16,565,644
Ensembl chr 6:16,445,955...16,565,665
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G |
Vsnl1 |
visinin-like 1 |
multiple interactions decreases response to substance |
ISO |
VSNL1 protein results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] VSNL1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:20419170 |
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NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions increases activity |
ISO |
Allopurinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] |
CTD |
PMID:3677084 PMID:22036979 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Yy1 |
YY1 transcription factor |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of YY1 protein [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of YY1 protein |
CTD |
PMID:32363662 |
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NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
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G |
Zc3h12a |
zinc finger CCCH type containing 12A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ZC3H12A mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
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G |
Zeb1 |
zinc finger E-box binding homeobox 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZEB1 mRNA [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [deoxynivalenol results in decreased expression of ZEB1 protein] |
CTD |
PMID:11893416 PMID:16979875 |
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NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
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G |
Zeb2 |
zinc finger E-box binding homeobox 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZEB2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
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G |
Zfp36 |
zinc finger protein 36 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ZFP36 mRNA |
CTD |
PMID:19945525 PMID:31068361 |
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NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
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G |
Znf235 |
zinc finger protein 235 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZNF235 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:79,698,989...79,708,439
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G |
Zwint |
ZW10 interacting kinetochore protein |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ZWINT mRNA |
CTD |
PMID:19031421 |
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NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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G |
Cnr1 |
cannabinoid receptor 1 |
affects binding |
ISO |
ricinoleic acid analog binds to CNR1 protein |
CTD |
PMID:16406364 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
ricinoleic acid analog binds to and affects the activity of CNR2 protein |
CTD |
PMID:16406364 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Ptgds |
prostaglandin D2 synthase |
affects binding |
ISO |
ricinoleic acid binds to PTGDS protein |
CTD |
PMID:26456343 |
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NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
ricinoleic acid analog binds to and affects the activity of TRPV1 protein |
CTD |
PMID:16406364 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB11 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB1B mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB4 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC2 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC5 mRNA |
CTD |
PMID:15770074 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC6 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
decreases activity |
EXP |
Soybean Oil results in decreased activity of ACAT1 protein |
CTD |
PMID:12559476 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression |
EXP |
Soybean Oil results in increased expression of BCL2 protein |
CTD |
PMID:15309441 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Cat |
catalase |
increases activity |
EXP |
Soybean Oil results in increased activity of CAT protein |
CTD |
PMID:12781854 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
increases expression |
EXP |
Soybean Oil results in increased expression of CCND1 mRNA |
CTD |
PMID:21088903 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
affects expression |
EXP |
Soybean Oil affects the expression of CYP4A1 mRNA |
CTD |
PMID:16079505 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases activity |
EXP |
Soybean Oil results in increased activity of CYP7A1 protein |
CTD |
PMID:12559476 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein] |
CTD |
PMID:11600134 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases activity |
EXP |
Soybean Oil results in increased activity of HMGCR protein |
CTD |
PMID:12559476 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Il12b |
interleukin 12B |
decreases expression |
ISO |
Soybean Oil results in decreased expression of IL12B mRNA |
CTD |
PMID:10065739 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Slc22a1 |
solute carrier family 22 member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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G |
Slc22a7 |
solute carrier family 22 member 7 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A7 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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G |
Alb |
albumin |
multiple interactions affects binding |
ISO |
[ALB protein binds to Myristic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Myristic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Myristic Acid] which results in decreased reduction of Dithionitrobenzoic Acid |
CTD |
PMID:25451573 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Myristic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects binding |
ISO |
Myristic Acid binds to PPARA protein |
CTD |
PMID:10403814 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
Myristic Acid results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCA1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG5 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG8 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of ACACA mRNA] |
CTD |
PMID:15066988 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Apoa4 |
apolipoprotein A4 |
multiple interactions |
EXP |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in increased expression of APOA4 protein |
CTD |
PMID:6631239 |
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NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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G |
Apoe |
apolipoprotein E |
multiple interactions |
EXP |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in decreased expression of APOE protein |
CTD |
PMID:6631239 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein alternative form]; Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] |
CTD |
PMID:28734741 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Cat |
catalase |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of CAT mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Triolein results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of FASN mRNA] |
CTD |
PMID:15066988 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Triolein results in increased expression of HMGCR mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
Triolein results in increased expression of MTTP mRNA |
CTD |
PMID:18356535 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
decreases expression |
ISO |
Triolein results in decreased expression of NPC1L1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased abundance of Triglycerides]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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