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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chelerythrine
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Accession:CHEBI:78373 term browser browse the term
Definition:A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Synonyms:exact_synonym: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
 related_synonym: 1,2-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium;   Formula=C21H18NO4;   InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1;   InChIKey=LLEJIEBFSOEYIV-UHFFFAOYSA-N;   SMILES=COc1ccc2c(c[n+](C)c3c4cc5OCOc5cc4ccc23)c1OC
 alt_id: CHEBI:31388
 xref: CAS:34316-15-9;   KEGG:C12227;   KNApSAcK:C00024634;   KNApSAcK:C00024660;   LINCS:LSM-1187
 xref_mesh: MESH:C016299
 xref: MetaCyc:CPD-16782;   PDBeChem:CTI;   PMID:23390024;   PMID:23900672;   PMID:24295957;   PMID:24300194;   PMID:24824737;   PMID:24928629;   PMID:24948079;   PMID:25010289;   Reaxys:3915260;   Wikipedia:Chelerythrine



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chelerythrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions
decreases activity
ISO chelerythrine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
chelerythrine results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions EXP chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of AHR protein] CTD PMID:10037446 PMID:15364539 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO chelerythrine inhibits the reaction [sodium arsenite inhibits the reaction [Cisplatin results in increased expression of BAX protein]] CTD PMID:12690470 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO chelerythrine inhibits the reaction [sodium arsenite inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]]
chelerythrine inhibits the reaction [Resveratrol affects the expression of BCL2 protein]
CTD PMID:12690470 PMID:31151226 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions ISO chelerythrine inhibits the reaction [Capsaicin results in increased expression of CALCA protein] CTD PMID:18752301 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Casp2 caspase 2 increases cleavage ISO chelerythrine results in increased cleavage of CASP2 protein CTD PMID:26124276 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
ISO malonic acid inhibits the reaction [chelerythrine results in increased activity of CASP3 protein]; Rotenone inhibits the reaction [chelerythrine results in increased activity of CASP3 protein]
Acetylcysteine inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]; Dithiothreitol inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]; quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]; S-methyl glutathione inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]
CTD PMID:21664962 PMID:26124276 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp6 caspase 6 increases cleavage ISO chelerythrine results in increased cleavage of CASP6 protein CTD PMID:26124276 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752
JBrowse link
G Casp7 caspase 7 increases cleavage ISO chelerythrine results in increased cleavage of CASP7 protein CTD PMID:26124276 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases cleavage
ISO malonic acid inhibits the reaction [chelerythrine results in increased activity of CASP9 protein]; Rotenone inhibits the reaction [chelerythrine results in increased activity of CASP9 protein]
chelerythrine results in increased cleavage of CASP9 protein
CTD PMID:21664962 PMID:26124276 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Casr calcium-sensing receptor multiple interactions ISO chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium] CTD PMID:21562303 NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions EXP chelerythrine inhibits the reaction [Phenylephrine results in increased expression of CCN1 mRNA] CTD PMID:15117851 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator decreases activity ISO chelerythrine results in decreased activity of CFTR protein CTD PMID:14744818 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO [AG 1879 co-treated with chelerythrine] inhibits the reaction [CXCL8 protein results in increased secretion of MMP9 protein]; chelerythrine inhibits the reaction [Acids results in increased expression of CXCL8 mRNA]; chelerythrine inhibits the reaction [Acids results in increased secretion of CXCL8 protein]; chelerythrine inhibits the reaction [CXCL8 protein results in increased phosphorylation of MAPK1 protein]; chelerythrine inhibits the reaction [CXCL8 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:15831558 PMID:19074641 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] CTD PMID:16901605 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP chelerythrine inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]] CTD PMID:10037446 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO chelerythrine inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:18436224 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egf epidermal growth factor multiple interactions ISO chelerythrine inhibits the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]]; chelerythrine inhibits the reaction [EGF protein results in decreased susceptibility to Acetaldehyde] CTD PMID:17991733 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO chelerythrine inhibits the reaction [Glucose results in increased expression of FN1 protein] CTD PMID:12388107 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO chelerythrine results in decreased activity of G6PD protein CTD PMID:19429815 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO chelerythrine inhibits the reaction [Acrolein results in increased secretion of GPT protein]; chelerythrine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein] CTD PMID:12755590 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions ISO chelerythrine inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein] CTD PMID:12690470 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions ISO chelerythrine inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein] CTD PMID:16178011 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Igf1 insulin-like growth factor 1 affects activity ISO chelerythrine affects the activity of IGF1 protein CTD PMID:11548882 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of IL1B mRNA]; chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased secretion of IL1B protein] CTD PMID:34006824 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
chelerythrine inhibits the reaction [Acids results in increased expression of IL6 mRNA]; chelerythrine inhibits the reaction [Acids results in increased secretion of IL6 protein]
chelerythrine inhibits the reaction [Ethanol results in increased expression of IL6 protein]; chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of IL6 mRNA]; chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased secretion of IL6 protein]
CTD PMID:19074641 PMID:24300194 PMID:34006824 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO chelerythrine results in decreased phosphorylation of and results in decreased activity of JAK2 protein CTD PMID:15746188 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Kcnd3 potassium voltage-gated channel, Shal-related family, member 3 multiple interactions ISO chelerythrine inhibits the reaction [Phenylephrine results in decreased activity of KCND3 protein alternative form] CTD PMID:11709419 NCBI chr 3:105,359,206...105,581,318
Ensembl chr 3:105,359,646...105,581,318
JBrowse link
G Lmna lamin A increases cleavage ISO chelerythrine results in increased cleavage of LMNA protein CTD PMID:26124276 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP
ISO
chelerythrine inhibits the reaction [evodiamine results in increased phosphorylation of MAPK1 protein]; chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
chelerythrine inhibits the reaction [CXCL8 protein results in increased phosphorylation of MAPK1 protein]
chelerythrine inhibits the reaction [Estradiol results in increased activity of MAPK1 protein]
CTD PMID:10037446 PMID:14511371 PMID:15831558 PMID:16713447 PMID:19854188 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO
EXP
chelerythrine inhibits the reaction [CXCL8 protein results in increased phosphorylation of MAPK3 protein]
chelerythrine inhibits the reaction [[Lead co-treated with Lipopolysaccharides] results in increased phosphorylation of MAPK3 protein]; chelerythrine inhibits the reaction [evodiamine results in increased phosphorylation of MAPK3 protein]; chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
chelerythrine inhibits the reaction [Estradiol results in increased activity of MAPK3 protein]
CTD PMID:10037446 PMID:14511371 PMID:15831558 PMID:16581537 PMID:16713447 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [AG 1879 co-treated with chelerythrine] inhibits the reaction [CXCL8 protein results in increased secretion of MMP9 protein] CTD PMID:15831558 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP chelerythrine inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:24300194 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions ISO chelerythrine inhibits the reaction [Resveratrol affects the expression of MYC protein] CTD PMID:31151226 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Myl1 myosin, light polypeptide 1 multiple interactions ISO chelerythrine inhibits the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein] CTD PMID:37963515 NCBI chr 1:66,963,454...66,987,091
Ensembl chr 1:66,963,454...66,984,563
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO chelerythrine inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:18436224 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased degradation of NFKBIA protein] CTD PMID:34006824 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions ISO [chelerythrine co-treated with tyrphostin 47] inhibits the reaction [Quercetin results in increased expression of NOS3 protein] CTD PMID:22557973 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nppa natriuretic peptide type A multiple interactions ISO chelerythrine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; chelerythrine promotes the reaction [2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]] CTD PMID:16787574 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nts neurotensin increases activity ISO chelerythrine results in increased activity of NTS protein CTD PMID:18313772 NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO chelerythrine inhibits the reaction [Testosterone results in increased expression of PCNA mRNA] CTD PMID:21374593 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory inhibitor subunit 14A multiple interactions ISO chelerythrine inhibits the reaction [Norepinephrine results in increased phosphorylation of PPP1R14A protein] CTD PMID:37963515 NCBI chr 7:28,988,732...28,992,817
Ensembl chr 7:28,988,733...28,993,226
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO chelerythrine inhibits the reaction [Capsaicin results in increased expression of PRKCA protein] CTD PMID:18752301 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]
[chelerythrine results in decreased activity of PRKCE protein] which results in decreased susceptibility to Phenylephrine
CTD PMID:12700091 PMID:21562303 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
JBrowse link
G Ptges3 prostaglandin E synthase 3 increases cleavage ISO chelerythrine results in increased cleavage of PTGES3 protein CTD PMID:26124276 NCBI chr10:127,894,851...127,913,123
Ensembl chr10:127,894,823...127,913,141
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO
EXP
chelerythrine inhibits the reaction [Acids results in increased activity of RELA protein]; chelerythrine inhibits the reaction [Glucose results in increased activity of RELA protein]
chelerythrine inhibits the reaction [Ethanol results in increased expression of RELA protein]; chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of RELA protein]
CTD PMID:12388107 PMID:19074641 PMID:24300194 PMID:34006824 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 decreases activity
multiple interactions
ISO chelerythrine results in decreased activity of SLC1A1 protein
chelerythrine inhibits the reaction [Pregabalin results in increased activity of SLC1A1 protein]; chelerythrine inhibits the reaction [Progesterone results in increased activity of SLC1A1 protein]
CTD PMID:17382927 PMID:22511482 PMID:23262392 PMID:23602688 PMID:24355585 NCBI chr19:28,812,535...28,891,360
Ensembl chr19:28,812,449...28,891,360
JBrowse link
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 multiple interactions ISO chelerythrine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 5:31,193,380...31,206,268
Ensembl chr 5:31,193,380...31,206,268
JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 increases cleavage ISO chelerythrine results in increased cleavage of SPTAN1 protein CTD PMID:26124276 NCBI chr 2:29,855,572...29,921,463
Ensembl chr 2:29,855,572...29,921,463
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO chelerythrine results in decreased phosphorylation of and results in decreased activity of STAT5A protein CTD PMID:15746188 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO chelerythrine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TH mRNA]; chelerythrine inhibits the reaction [HU 211 results in decreased expression of TH mRNA] CTD PMID:18992715 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO chelerythrine inhibits the reaction [EGF protein inhibits the reaction [Acetaldehyde affects the localization of TJP1 protein]] CTD PMID:17991733 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP chelerythrine inhibits the reaction [Ethanol results in increased expression of TNF protein]; chelerythrine inhibits the reaction [lead acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; chelerythrine inhibits the reaction [lead acetate results in increased expression of TNF protein]; chelerythrine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of TNF mRNA]; chelerythrine inhibits the reaction [perfluorooctane sulfonic acid results in increased secretion of TNF protein]; chelerythrine inhibits the reaction [TNF protein results in increased transport of Chlorides]; chelerythrine inhibits the reaction [TNF protein results in increased transport of Potassium] CTD PMID:10783394 PMID:15302094 PMID:16581537 PMID:24300194 PMID:34006824 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnni3 troponin I, cardiac 3 multiple interactions EXP chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNI3 protein] CTD PMID:12003851 NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228
JBrowse link
G Tnnt2 troponin T2, cardiac multiple interactions EXP chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNT2 protein] CTD PMID:12003851 NCBI chr 1:135,763,933...135,780,006
Ensembl chr 1:135,764,092...135,779,998
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO chelerythrine inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein] CTD PMID:18752301 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        antimicrobial agent 19546
          antibacterial agent 16135
            chelerythrine 56
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            organic molecule 21647
                              organic cyclic compound 21252
                                organic heterocyclic compound 20352
                                  organonitrogen heterocyclic compound 19099
                                    benzophenanthridine 136
                                      benzophenanthridine alkaloid 114
                                        chelerythrine 56
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