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ONTOLOGY REPORT - ANNOTATIONS


Term:chelerythrine
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Accession:CHEBI:78373 term browser browse the term
Definition:A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Synonyms:exact_synonym: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
 related_synonym: 1,2-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium;   Formula=C21H18NO4;   InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1;   InChIKey=LLEJIEBFSOEYIV-UHFFFAOYSA-N;   SMILES=COc1ccc2c(c[n+](C)c3c4cc5OCOc5cc4ccc23)c1OC
 alt_id: CHEBI:31388
 xref: CAS:34316-15-9 "ChemIDplus";   CAS:34316-15-9 "KEGG COMPOUND";   KEGG:C12227;   KNApSAcK:C00024634;   KNApSAcK:C00024660;   LINCS:LSM-1187
 xref_mesh: MESH:C016299
 xref: MetaCyc:CPD-16782;   PDBeChem:CTI;   PMID:23390024 "Europe PMC";   PMID:23900672 "Europe PMC";   PMID:24295957 "Europe PMC";   PMID:24300194 "Europe PMC";   PMID:24824737 "Europe PMC";   PMID:24928629 "Europe PMC";   PMID:24948079 "Europe PMC";   PMID:25010289 "Europe PMC";   Reaxys:3915260 "Reaxys";   Wikipedia:Chelerythrine


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chelerythrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 JBrowse link 2 69,238,282 69,342,616 RGD:6480464
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Calca calcitonin/calcitonin-related polypeptide, alpha JBrowse link 7 114,625,981 114,636,910 RGD:6480464
G Casp2 caspase 2 JBrowse link 6 42,264,902 42,282,508 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp6 caspase 6 JBrowse link 3 129,901,415 129,914,112 RGD:6480464
G Casp7 caspase 7 JBrowse link 19 56,396,833 56,442,348 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Casr calcium-sensing receptor JBrowse link 16 36,490,585 36,562,141 RGD:6480464
G Ccn1 cellular communication network factor 1 JBrowse link 3 145,646,971 145,649,985 RGD:6480464
G Cftr cystic fibrosis transmembrane conductance regulator JBrowse link 6 18,170,687 18,322,770 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:6480464
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:6480464
G Egf epidermal growth factor JBrowse link 3 129,677,574 129,755,322 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 1 71,585,473 71,653,280 RGD:6480464
G G6pdx glucose-6-phosphate dehydrogenase X-linked JBrowse link X 74,409,483 74,428,880 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Hspa1a heat shock protein 1A JBrowse link 17 34,969,359 34,972,156 RGD:6480464
G Hspd1 heat shock protein 1 (chaperonin) JBrowse link 1 55,077,833 55,088,243 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 19 29,251,803 29,313,095 RGD:6480464
G Kcnd3 potassium voltage-gated channel, Shal-related family, member 3 JBrowse link 3 105,451,890 105,674,002 RGD:6480464
G Lmna lamin A JBrowse link 3 88,481,148 88,509,932 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mpo myeloperoxidase JBrowse link 11 87,793,784 87,804,412 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 5 134,220,053 134,229,628 RGD:6480464
G Nos3 nitric oxide synthase 3, endothelial cell JBrowse link 5 24,364,816 24,384,474 RGD:6480464
G Nppa natriuretic peptide type A JBrowse link 4 148,000,722 148,002,074 RGD:6480464
G Nts neurotensin JBrowse link 10 102,481,756 102,490,418 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 2 132,249,286 132,253,180 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 11 107,933,387 108,343,888 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 17 86,167,785 86,657,919 RGD:6480464
G Ptges3 prostaglandin E synthase 3 JBrowse link 10 128,058,982 128,077,254 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 JBrowse link 19 28,835,135 28,913,960 RGD:6480464
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 JBrowse link 5 31,036,036 31,048,924 RGD:6480464
G Sptan1 spectrin alpha, non-erythrocytic 1 JBrowse link 2 29,965,560 30,031,451 RGD:6480464
G Stat5a signal transducer and activator of transcription 5A JBrowse link 11 100,859,351 100,885,169 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 7 142,892,779 142,899,995 RGD:6480464
G Tjp1 tight junction protein 1 JBrowse link 7 65,296,165 65,527,850 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnni3 troponin I, cardiac 3 JBrowse link 7 4,518,305 4,522,718 RGD:6480464
G Tnnt2 troponin T2, cardiac JBrowse link 1 135,836,315 135,852,268 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 11 73,234,149 73,261,322 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20971
    role 20952
      biological role 20950
        antimicrobial agent 18045
          antibacterial agent 13241
            chelerythrine 51
Path 2
Term Annotations click to browse term
  CHEBI ontology 20971
    subatomic particle 20965
      composite particle 20965
        hadron 20965
          baryon 20965
            nucleon 20965
              atomic nucleus 20965
                atom 20965
                  main group element atom 20803
                    p-block element atom 20803
                      carbon group element atom 20543
                        carbon atom 20519
                          organic molecular entity 20519
                            organic molecule 20371
                              organic cyclic compound 20047
                                organic heterocyclic compound 18970
                                  organonitrogen heterocyclic compound 17422
                                    benzophenanthridine 122
                                      benzophenanthridine alkaloid 99
                                        chelerythrine 51
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.