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ONTOLOGY REPORT - ANNOTATIONS


Term:chelerythrine
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Accession:CHEBI:78373 term browser browse the term
Definition:A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.
Synonyms:exact_synonym: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
 related_synonym: 1,2-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium;   Formula=C21H18NO4;   InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1;   InChIKey=LLEJIEBFSOEYIV-UHFFFAOYSA-N;   SMILES=COc1ccc2c(c[n+](C)c3c4cc5OCOc5cc4ccc23)c1OC
 alt_id: CHEBI:31388
 xref: CAS:34316-15-9 "ChemIDplus";   CAS:34316-15-9 "KEGG COMPOUND";   KEGG:C12227;   KNApSAcK:C00024634;   KNApSAcK:C00024660;   LINCS:LSM-1187
 xref_mesh: MESH:C016299
 xref: MetaCyc:CPD-16782;   PDBeChem:CTI;   PMID:23390024 "Europe PMC";   PMID:23900672 "Europe PMC";   PMID:24295957 "Europe PMC";   PMID:24300194 "Europe PMC";   PMID:24824737 "Europe PMC";   PMID:24928629 "Europe PMC";   PMID:24948079 "Europe PMC";   PMID:25010289 "Europe PMC";   Reaxys:3915260 "Reaxys";   Wikipedia:Chelerythrine


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chelerythrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:6480464
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:6480464
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6480464
G Kcnd3 potassium voltage-gated channel subfamily D member 3 JBrowse link 2 207,923,775 208,140,727 RGD:6480464
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Nts neurotensin JBrowse link 7 44,111,594 44,120,998 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:6480464
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc1a1 solute carrier family 1 member 1 JBrowse link 1 246,955,017 247,035,159 RGD:6480464
G Slc5a6 solute carrier family 5 member 6 JBrowse link 6 26,685,823 26,697,110 RGD:6480464
G Sptan1 spectrin, alpha, non-erythrocytic 1 JBrowse link 3 8,534,437 8,599,259 RGD:6480464
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Tjp1 tight junction protein 1 JBrowse link 1 126,146,489 126,515,359 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:6480464
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        antimicrobial agent 17148
          antibacterial agent 12900
            chelerythrine 50
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic molecule 19332
                              organic cyclic compound 19083
                                organic heterocyclic compound 18154
                                  organonitrogen heterocyclic compound 16967
                                    benzophenanthridine 119
                                      benzophenanthridine alkaloid 96
                                        chelerythrine 50
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.