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Term:fluorometholone acetate
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Accession:CHEBI:78354 term browser browse the term
Definition:A steroid ester resulting from the formal condensation of the 17-hydroxy function of fluorometholone with acetic acid. Used in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.
Synonyms:exact_synonym: (6alpha,11beta)-9-fluoro-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl acetate;   9-fluoro-11beta-hydroxy-6alpha-methyl-3,20-dioxopregna-1,4-dien-17-yl acetate
 related_synonym: 6alpha-Methyl-9alpha-fluoro-17-acetoxy-21-deoxyprednisolone;   9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate;   Flarex;   Fluorometholone 17-acetate;   Formula=C24H31FO5;   InChI=1S/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1;   InChIKey=YRFXGQHBPBMFHW-SBTZIJSASA-N;   SMILES=C[C@H]1C[C@H]2[C@@H]3CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]2(C)C=CC(=O)C=C12
 alt_id: CHEBI:34765
 xref: CAS:3801-06-7;   DrugBank:DB00324;   Drug_Central:4647;   KEGG:C14629;   KEGG:D04221;   PMID:11167281;   PMID:12678152;   PMID:17186258;   PMID:17435423;   PMID:18631332;   PMID:20447966;   PMID:6375979;   PMID:6398026;   PMID:7073584;   Patent:US5149693;   Patent:WO0025727;   Patent:WO9001933;   Reaxys:13572136;   Wikipedia:Fluorometholone

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  CHEBI ontology 19758
    role 19705
      application 19359
        anti-inflammatory agent 14958
          anti-inflammatory drug 13610
            fluorometholone acetate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      ketone 15948
                                        oxo steroid 9289
                                          3-oxo steroid 8814
                                            3-oxo-Delta(4) steroid 7942
                                              progesterone 2713
                                                Delta(1)-progesterone 235
                                                  fluorometholone 1
                                                    fluorometholone acetate 0
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