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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iron dextran
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Accession:CHEBI:78291 term browser browse the term
Definition:Please consider adding concept for iron dextran. CAS# 9004-66-4. Thank you.
Synonyms:related_synonym: Iron dextran complex
 xref: CAS:9004-66-4;   KEGG:C13774;   KEGG:D02141
 xref_mesh: MESH:D007505



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iron dextran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [ADIPOQ protein results in increased expression of BCL2L1 protein] inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; dorsomorphin inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]; GW 6471 inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]; Iron-Dextran Complex inhibits the reaction [ADIPOQ protein results in increased expression of and results in increased activity of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]; tin protoporphyrin IX promotes the reaction [Iron-Dextran Complex inhibits the reaction [ADIPOQ protein results in increased expression of and results in increased activity of HMOX1 protein]] CTD PMID:20709802 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Iron-Dextran Complex affects the reaction [AHR affects the susceptibility to Tetrachlorodibenzodioxin] CTD PMID:9443932 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of AKT1 protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of AKT1 protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of AKT1 protein] CTD PMID:32828744 PMID:33580994 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein]; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein]; SB 203580 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of BAX protein] CTD PMID:33285147 PMID:33393188 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein] CTD PMID:33285147 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
ISO [ADIPOQ protein results in increased expression of BCL2L1 protein] inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; [pirinixic acid results in increased expression of BCL2L1 protein] inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; Bilirubin promotes the reaction [Iron-Dextran Complex results in increased expression of BCL2L1 protein] CTD PMID:20709802 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression EXP Iron-Dextran Complex results in decreased expression of BGLAP mRNA CTD PMID:29122540 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions
affects expression
ISO Diltiazem inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]; Nimodipine inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]; Verapamil inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein]
CTD PMID:27095094 PMID:33285147 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
ISO
EXP
[ADIPOQ protein results in increased expression of BCL2L1 protein] inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CASP3 protein; [pirinixic acid results in increased expression of BCL2L1 protein] inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; Bilirubin inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]; dorsomorphin inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]; GW 6471 inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]; tin protoporphyrin IX inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]
Iron-Dextran Complex results in increased expression of CASP3 protein modified form
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein; Arginine inhibits the reaction [Iron-Dextran Complex results in increased expression of CASP3 protein modified form]; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased expression of CASP3 protein modified form]]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]; tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased expression of CASP3 protein modified form]; U 0126 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of CASP3 protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of CASP3 protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of CASP3 protein]
CTD PMID:20709802 PMID:32135237 PMID:32828744 PMID:33285147 PMID:33393188 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions
decreases activity
increases expression
increases activity
ISO
EXP
Iron-Dextran Complex promotes the reaction [Benzoyl Peroxide results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [cumene hydroperoxide results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [mezerein results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased activity of CAT protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased activity of CAT protein]
Iron-Dextran Complex results in decreased activity of CAT protein
Arginine inhibits the reaction [Iron-Dextran Complex results in decreased activity of CAT protein]; Cyclosporine inhibits the reaction [Iron-Dextran Complex results in decreased activity of CAT protein]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased activity of CAT protein]]; Edaravone inhibits the reaction [Iron-Dextran Complex results in decreased activity of CAT protein]; tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased activity of CAT protein]
Iron-Dextran Complex results in increased expression of CAT protein
Iron-Dextran Complex results in increased activity of CAT protein
CTD PMID:12065085 PMID:24120471 PMID:28700905 PMID:32135237 PMID:33580994 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein] CTD PMID:33285147 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO Iron-Dextran Complex results in increased expression of COL1A1 protein
Diltiazem inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]; Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]; Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]
CTD PMID:27095094 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression EXP Iron-Dextran Complex results in increased expression of CYBA protein CTD PMID:15086920 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression EXP Iron-Dextran Complex results in increased expression of CYBB protein CTD PMID:28700905 PMID:29990562 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO Iron-Dextran Complex inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Iron-Dextran Complex results in decreased activity of CYP1A1 protein
CTD PMID:9443932 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO Iron-Dextran Complex inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Iron-Dextran Complex results in decreased activity of CYP1A2 protein
CTD PMID:9443932 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 multiple interactions
decreases expression
ISO [Iron-Dextran Complex results in decreased expression of DDAH2 protein] which results in increased abundance of N,N-dimethylarginine; Arginine inhibits the reaction [[Iron-Dextran Complex results in decreased expression of DDAH2 protein] which results in increased abundance of N,N-dimethylarginine]; Arginine inhibits the reaction [Iron-Dextran Complex results in decreased expression of DDAH2 protein]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased abundance of Nitric Oxide]]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased activity of CAT protein]]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased phosphorylation of NOS3 protein]]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased abundance of Malondialdehyde]]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased abundance of N,N-dimethylarginine]]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased abundance of Reactive Oxygen Species]]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased expression of CASP3 protein modified form]]; tetramethylpyrazine inhibits the reaction [[Iron-Dextran Complex results in decreased expression of DDAH2 protein] which results in increased abundance of N,N-dimethylarginine]; tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased expression of DDAH2 protein] CTD PMID:32135237 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of FOS protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of FOS protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of FOS protein] CTD PMID:32828744 PMID:33580994 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression
ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 mRNA; Diltiazem inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein]; Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein]; Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of FTH1 protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein]
CTD PMID:27095094 PMID:33285147 PMID:33393188 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GPT protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GPT protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GPT protein] CTD PMID:32828744 PMID:33580994 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased activity of GSR protein CTD PMID:33393188 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression
ISO [Iron-Dextran Complex co-treated with Tetrachlorodibenzodioxin] results in increased expression of GSTM1 protein
Iron-Dextran Complex results in increased expression of GSTM1 protein
CTD PMID:9443932 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
increases expression
ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of HAMP mRNA; Diltiazem promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA]; Nimodipine promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA]; Verapamil promotes the reaction [Iron-Dextran Complex results in increased expression of HAMP mRNA] CTD PMID:27095094 PMID:33393188 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
Iron-Dextran Complex inhibits the reaction [ADIPOQ protein results in increased expression of and results in increased activity of HMOX1 protein]; tin protoporphyrin IX promotes the reaction [Iron-Dextran Complex inhibits the reaction [ADIPOQ protein results in increased expression of and results in increased activity of HMOX1 protein]]
Iron-Dextran Complex results in increased expression of HMOX1 mRNA; Iron-Dextran Complex results in increased expression of HMOX1 protein
CTD PMID:20709802 PMID:23525258 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL1B protein; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL1B protein] CTD PMID:32828744 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP
ISO
Iron-Dextran Complex results in increased expression of IL6 mRNA
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of IL6 protein]
CTD PMID:29122540 PMID:32828744 PMID:33285147 PMID:33580994 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
EXP
ISO
Iron-Dextran Complex results in increased phosphorylation of MAPK1 protein
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]
CTD PMID:28700905 PMID:33285147 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
EXP
ISO
Iron-Dextran Complex results in increased phosphorylation of MAPK3 protein
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:28700905 PMID:33285147 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein] CTD PMID:33285147 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Iron-Dextran Complex results in increased expression of NOS2 protein CTD PMID:28700905 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
EXP
ISO
Iron-Dextran Complex results in increased expression of and results in increased phosphorylation of NOS3 protein
Arginine inhibits the reaction [Iron-Dextran Complex results in decreased phosphorylation of NOS3 protein]; DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased phosphorylation of NOS3 protein]]; tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in decreased phosphorylation of NOS3 protein]
CTD PMID:29990562 PMID:32135237 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
ISO Iron-Dextran Complex promotes the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [cumene hydroperoxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Hydrogen Peroxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [mezerein results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]
Iron-Dextran Complex results in increased activity of ODC1 protein
CTD PMID:12065085 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [taxifolin co-treated with [Iron-Dextran Complex results in increased abundance of Iron]] results in increased expression of PCNA protein CTD PMID:32828744 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions EXP [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of PIK3CA protein; [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of PIK3CA protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of PIK3CA protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased phosphorylation of PIK3CA protein] CTD PMID:32828744 PMID:33580994 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]; SB 203580 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]; U 0126 inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]
[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which affects the localization of RELA protein]
CTD PMID:33285147 PMID:33580994 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rho rhodopsin multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RHO mRNA; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RHO mRNA] CTD PMID:33285147 NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773
JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RPE65 mRNA; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of RPE65 mRNA] CTD PMID:33285147 NCBI chr 2:248,766,497...248,798,403
Ensembl chr 2:248,766,612...248,798,403
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions
increases expression
ISO Diltiazem inhibits the reaction [Iron-Dextran Complex results in increased expression of SLC11A2 protein]; Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of SLC11A2 protein]; Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of SLC11A2 protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein]
CTD PMID:27095094 PMID:33285147 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC40A1 mRNA CTD PMID:33393188 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP Iron-Dextran Complex results in increased expression of SOD1 protein CTD PMID:29990562 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression EXP Iron-Dextran Complex results in decreased expression of SOD2 protein CTD PMID:28700905 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tfr2 transferrin receptor 2 increases expression ISO Iron-Dextran Complex results in increased expression of TFR2 protein CTD PMID:27095094 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein] CTD PMID:33285147 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases secretion EXP Iron-Dextran Complex results in increased secretion of TGFB1 protein CTD PMID:23525258 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein; Ergothioneine inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein]; taxifolin inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein]
[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TNF protein]
CTD PMID:32828744 PMID:33285147 PMID:33580994 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression EXP Iron-Dextran Complex results in decreased expression of TNFRSF11B mRNA CTD PMID:29122540 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 increases expression EXP Iron-Dextran Complex results in increased expression of TNFSF11 mRNA CTD PMID:29122540 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TXNIP mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TXNIP protein CTD PMID:33393188 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of TXNRD1 mRNA; [Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TXNRD1 protein CTD PMID:33393188 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Urod uroporphyrinogen decarboxylase multiple interactions ISO Iron-Dextran Complex promotes the reaction [Tetrachlorodibenzodioxin results in decreased activity of UROD protein] CTD PMID:9443932 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          carbon atom 19609
            organic molecular entity 19609
              iron dextran 50
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            iron dextran 50
paths to the root