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ONTOLOGY REPORT - ANNOTATIONS


Term:oxcarbazepine
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Accession:CHEBI:7824 term browser browse the term
Definition:A dibenzoazepine derivative, having a carbamoyl group at the ring nitrogen, substituted with an oxo group at C-4 of the azepeine ring which is also hydrogenated at C-4 and C-5. It is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy.
Synonyms:exact_synonym: 10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
 related_synonym: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide;   Formula=C15H12N2O2;   InChI=1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19);   InChIKey=CTRLABGOLIVAIY-UHFFFAOYSA-N;   SMILES=NC(=O)N1c2ccccc2CC(=O)c2ccccc12;   oxcarbazepina;   oxcarbazepinum
 xref: CAS:28721-07-5 "ChemIDplus";   CAS:28721-07-5 "KEGG COMPOUND";   Drug_Central:2017 "DrugCentral";   KEGG:C07492;   KEGG:D00533;   LINCS:LSM-5219
 xref_mesh: MESH:C036006
 xref: PMID:21924464 "Europe PMC"


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oxcarbazepine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:6480464
G Adra2c adrenoceptor alpha 2C JBrowse link 14 80,730,307 80,732,010 RGD:6480464
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:6480464
G Cbr3 carbonyl reductase 3 JBrowse link 11 33,909,417 33,917,674 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Dhrs7 dehydrogenase/reductase 7 JBrowse link 6 95,522,577 95,541,393 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor alpha1 subunit JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit JBrowse link 14 39,662,411 39,801,082 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Shbg sex hormone binding globulin JBrowse link 10 56,219,861 56,237,354 RGD:6480464
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            drug allergen 9747
              oxcarbazepine 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              oxcarbazepine 14
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