Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxaprozin
go back to main search page
Accession:CHEBI:7822 term browser browse the term
Definition:A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis.
Synonyms:exact_synonym: 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
 related_synonym: Danoprox;   Daypro;   Dayrun;   Deflam;   Duraprox;   Formula=C18H15NO3;   InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21);   InChIKey=OFPXSFXSNFPTHF-UHFFFAOYSA-N;   SMILES=OC(=O)CCc1nc(-c2ccccc2)c(o1)-c1ccccc1;   Walix;   oxaprozina;   oxaprozine;   oxaprozinum
 xref: CAS:21256-18-8;   DrugBank:DB00991;   Drug_Central:2013;   HMDB:HMDB0015126;   KEGG:C07356;   KEGG:D00463;   LINCS:LSM-2553
 xref_mesh: MESH:C008729
 xref: PMID:1603605;   PMID:1617910;   PMID:19338579;   PMID:19672323;   PMID:20206429;   PMID:23865335;   PMID:385873;   PMID:6432657;   PMID:6611288;   PMID:6863578;   PMID:9459947;   Patent:FR2001036;   Patent:GB1206403;   Patent:US3578671;   Patent:WO2007082542;   Reaxys:1083168;   Wikipedia:Oxaprozin



show annotations for term's descendants           Sort by:
 
oxaprozin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngfr nerve growth factor receptor increases expression ISO oxaprozin results in increased expression of NGFR protein CTD PMID:17409433 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO oxaprozin results in increased activity of PPARG protein CTD PMID:12065695 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Oxaprozin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      biological role 19757
        pharmacological role 18838
          analgesic 13301
            oxaprozin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18725
                              organic divalent group 18716
                                organodiyl group 18716
                                  carbonyl group 18664
                                    carbonyl compound 18664
                                      carboxylic acid 18361
                                        monocarboxylic acid 17631
                                          fatty acid 16010
                                            saturated fatty acid 15984
                                              propionic acid 3688
                                                oxaprozin 3
paths to the root