Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:7822 term browser browse the term
Definition:A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis.
Synonyms:exact_synonym: 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
 related_synonym: Danoprox;   Daypro;   Dayrun;   Deflam;   Duraprox;   Formula=C18H15NO3;   InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21);   InChIKey=OFPXSFXSNFPTHF-UHFFFAOYSA-N;   SMILES=OC(=O)CCc1nc(-c2ccccc2)c(o1)-c1ccccc1;   Walix;   oxaprozina;   oxaprozine;   oxaprozinum
 xref: CAS:21256-18-8 "ChemIDplus";   CAS:21256-18-8 "KEGG COMPOUND";   DrugBank:DB00991;   Drug_Central:2013 "DrugCentral";   HMDB:HMDB0015126;   KEGG:C07356;   KEGG:D00463;   LINCS:LSM-2553
 xref_mesh: MESH:C008729
 xref: PMID:1603605 "Europe PMC";   PMID:1617910 "Europe PMC";   PMID:19338579 "Europe PMC";   PMID:19672323 "Europe PMC";   PMID:20206429 "Europe PMC";   PMID:23865335 "Europe PMC";   PMID:385873 "Europe PMC";   PMID:6432657 "Europe PMC";   PMID:6611288 "Europe PMC";   PMID:6863578 "Europe PMC";   PMID:9459947 "Europe PMC";   Patent:FR2001036;   Patent:GB1206403;   Patent:US3578671;   Patent:WO2007082542;   Reaxys:1083168 "Reaxys";   Wikipedia:Oxaprozin

show annotations for term's descendants       view all columns           Sort by:
oxaprozin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          analgesic 13037
            oxaprozin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          fatty acid 15814
                                            saturated fatty acid 15782
                                              propionic acid 3641
                                                oxaprozin 3
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.