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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:food bleaching agent
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Accession:CHEBI:78003 term browser browse the term
Definition:A food additive that is used for the purpose of decolourising food.
Synonyms:related_synonym: food bleaching agents


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sulfur dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of AGR2 mRNA CTD PMID:29621558 NCBI chr12:35,992,925...36,004,081
Ensembl chr12:35,992,907...36,004,087
JBrowse link
G Arc activity regulated cytoskeletal-associated protein decreases expression ISO Sulfur Dioxide results in decreased expression of ARC mRNA CTD PMID:25534910 NCBI chr15:74,669,081...74,672,570
Ensembl chr15:74,669,083...74,672,570
JBrowse link
G Areg amphiregulin multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of AREG mRNA CTD PMID:29621558 NCBI chr 5:91,139,599...91,148,432
Ensembl chr 5:91,139,599...91,148,432
JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of BAX protein; [Sulfur Dioxide co-treated with sodium arsenite] results in increased expression of BAX mRNA CTD PMID:27521637, PMID:30195209 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
EXP [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of BCL2 mRNA
Sulfur Dioxide results in decreased expression of BCL2 mRNA
CTD PMID:30195209 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] CTD PMID:30503585 NCBI chr11:101,288,258...101,302,286
Ensembl chr11:101,285,952...101,302,286
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression ISO Sulfur Dioxide results in decreased expression of CAMK2A protein modified form CTD PMID:25534910 NCBI chr18:60,925,307...60,988,152
Ensembl chr18:60,925,618...60,988,152
JBrowse link
G Capn1 calpain 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] CTD PMID:30503585 NCBI chr19:5,988,545...6,015,825
Ensembl chr19:5,988,545...6,015,897
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form] CTD PMID:30503585 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
increases expression
ISO
EXP
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein; Sulfur Dioxide results in increased expression of and results in increased activity of CASP3 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP3 mRNA
Sulfur Dioxide results in decreased activity of CASP3 protein
[Sulfur Dioxide co-treated with sodium arsenite] results in increased activity of CASP3 protein; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein
Sulfur Dioxide results in increased expression of CASP3 mRNA
CTD PMID:19621461, PMID:21873648, PMID:26209559, PMID:30195209, PMID:30503585, PMID:31268311 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of CASP8 mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP8 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP8 protein
CTD PMID:19621461, PMID:30503585, PMID:31268311 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of CASP9 mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of CASP9 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of CASP9 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide results in increased expression of and results in increased activity of CASP9 protein
CTD PMID:19621461, PMID:30503585, PMID:31268311 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase decreases activity
multiple interactions
ISO Sulfur Dioxide results in decreased activity of CAT protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA]
CTD PMID:10871429, PMID:30503585 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of CCL1 mRNA CTD PMID:29621558 NCBI chr11:82,176,666...82,179,812
Ensembl chr11:82,176,657...82,305,690
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of CCL2 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]
CTD PMID:27565714, PMID:30503585 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 decreases expression ISO Sulfur Dioxide results in decreased expression of CCL20 protein CTD PMID:27565714 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression
EXP [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CDH2 protein
Sulfur Dioxide results in decreased expression of CDH2 protein
CTD PMID:27237588 NCBI chr18:16,588,877...16,809,246
Ensembl chr18:16,588,877...16,809,246
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A multiple interactions
decreases expression
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of CDKN2A protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of CDKN2A protein]
Sulfur Dioxide results in decreased expression of CDKN2A mRNA; Sulfur Dioxide results in decreased expression of CDKN2A protein
Sulfur Dioxide results in increased expression of CDKN2A protein
CTD PMID:19408242, PMID:19434695, PMID:20064080 NCBI chr 4:89,274,473...89,294,619
Ensembl chr 4:89,274,471...89,294,653
JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CLCA1 mRNA CTD PMID:29621558 NCBI chr 3:145,004,537...145,032,776
Ensembl chr 3:145,003,817...145,032,776
JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions
EXP Sulfur Dioxide results in decreased expression of CLDN11 protein
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CLDN11 protein
CTD PMID:27237588 NCBI chr 3:31,149,920...31,164,326
Ensembl chr 3:31,149,920...31,164,324
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) multiple interactions EXP CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Col11a1 collagen, type XI, alpha 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of COL11A1 mRNA CTD PMID:29621558 NCBI chr 3:114,030,479...114,220,756
Ensembl chr 3:114,030,540...114,220,718
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 increases expression ISO Sulfur Dioxide results in increased expression of COX4I1 mRNA CTD PMID:22677886 NCBI chr 8:120,668,225...120,674,209
Ensembl chr 8:120,668,222...120,674,207
JBrowse link
G Ctnna1 catenin (cadherin associated protein), alpha 1 multiple interactions
decreases expression
EXP [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of CTNNA1 protein
Sulfur Dioxide results in decreased expression of CTNNA1 protein
CTD PMID:27237588 NCBI chr18:35,118,902...35,254,776
Ensembl chr18:35,118,859...35,254,779
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases expression ISO Sulfur Dioxide results in increased expression of CXCL1 protein CTD PMID:27565714 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of CXCL11 mRNA CTD PMID:29621558 NCBI chr 5:92,359,544...92,363,296
Ensembl chr 5:92,359,544...92,365,485
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein] CTD PMID:30503585 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
decreases expression
ISO Sulfur Dioxide results in decreased activity of CYP1A1 protein
Sulfur Dioxide results in decreased expression of CYP1A1 mRNA
CTD PMID:16023800 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
decreases expression
ISO Sulfur Dioxide results in decreased activity of CYP1A2 protein
Sulfur Dioxide results in decreased expression of CYP1A2 mRNA
CTD PMID:16023800 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of DDIT3 mRNA CTD PMID:31268311 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression ISO Sulfur Dioxide affects the expression of DLG4 protein CTD PMID:25534910 NCBI chr11:70,017,203...70,045,535
Ensembl chr11:70,016,942...70,047,522
JBrowse link
G Dnm1l dynamin 1-like multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of DNM1L protein CTD PMID:27521637 NCBI chr16:16,312,228...16,359,038
Ensembl chr16:16,312,230...16,358,959
JBrowse link
G Dsg2 desmoglein 2 multiple interactions
decreases expression
EXP [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 mRNA; [Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of DSG2 protein
Sulfur Dioxide results in decreased expression of DSG2 mRNA; Sulfur Dioxide results in decreased expression of DSG2 protein
CTD PMID:27237588 NCBI chr18:20,558,074...20,604,526
Ensembl chr18:20,558,074...20,604,521
JBrowse link
G Edn1 endothelin 1 increases expression
multiple interactions
ISO
EXP
Sulfur Dioxide results in increased expression of EDN1 mRNA; Sulfur Dioxide results in increased expression of EDN1 protein
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein
CTD PMID:20083630, PMID:30090456 NCBI chr13:42,301,476...42,307,990
Ensembl chr13:42,301,476...42,307,990
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of FIS1 protein CTD PMID:27521637 NCBI chr 5:136,953,275...136,966,234
Ensembl chr 5:136,953,275...136,966,234
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of FOS protein
Sulfur Dioxide results in increased expression of FOS mRNA; Sulfur Dioxide results in increased expression of FOS protein
CTD PMID:19408242, PMID:19434695 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions
EXP Sulfur Dioxide results in decreased expression of GJA1 protein
[Sodium Fluoride co-treated with Sulfur Dioxide] results in decreased expression of GJA1 protein
CTD PMID:27237588 NCBI chr10:56,377,300...56,390,419
Ensembl chr10:56,377,330...56,402,513
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] CTD PMID:30503585 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA] CTD PMID:30503585 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) decreases expression ISO Sulfur Dioxide results in decreased expression of GRIA1 mRNA CTD PMID:25534910 NCBI chr11:57,011,571...57,330,244
Ensembl chr11:57,011,387...57,330,244
JBrowse link
G Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) decreases expression ISO Sulfur Dioxide results in decreased expression of GRIA2 mRNA CTD PMID:25534910 NCBI chr 3:80,681,450...80,804,227
Ensembl chr 3:80,681,450...80,802,835
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) decreases expression ISO Sulfur Dioxide results in decreased expression of GRIN1 mRNA CTD PMID:25534910 NCBI chr 2:25,291,177...25,319,187
Ensembl chr 2:25,291,181...25,319,187
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) decreases expression ISO Sulfur Dioxide results in decreased expression of GRIN2A mRNA CTD PMID:25534910 NCBI chr16:9,567,901...9,996,083
Ensembl chr16:9,567,898...9,995,560
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions
decreases expression
increases cleavage
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased cleavage of GRIN2B protein]
Sulfur Dioxide results in decreased expression of GRIN2B mRNA
CTD PMID:21873648, PMID:25534910 NCBI chr 6:135,713,221...136,173,615
Ensembl chr 6:135,713,233...136,173,511
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein] CTD PMID:30503585 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of HRAS protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of HRAS protein]
Sulfur Dioxide results in increased expression of HRAS mRNA; Sulfur Dioxide results in increased expression of HRAS protein
CTD PMID:19408242, PMID:20064080 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of HSPA5 mRNA
CTD PMID:30503585, PMID:31268311 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of ICAM1 mRNA; Sulfur Dioxide results in increased expression of ICAM1 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
CTD PMID:20083630, PMID:30503585 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO
EXP
Sulfur Dioxide results in increased expression of IFNG protein
[Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IFNG protein
CTD PMID:27565714, PMID:29621558 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of IKBKB mRNA CTD PMID:31268311 NCBI chr 8:22,659,205...22,706,589
Ensembl chr 8:22,659,212...22,706,589
JBrowse link
G Il10 interleukin 10 increases expression ISO Sulfur Dioxide results in increased expression of IL10 protein CTD PMID:27565714 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il13 interleukin 13 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in decreased expression of IL13 mRNA CTD PMID:29621558 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Il17a interleukin 17A multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL17A protein CTD PMID:29621558 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Il18 interleukin 18 increases expression ISO Sulfur Dioxide results in increased expression of IL18 protein CTD PMID:27565714 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of IL1B protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
CTD PMID:27565714, PMID:30503585 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il2 interleukin 2 increases expression ISO Sulfur Dioxide results in increased expression of IL2 protein CTD PMID:27565714 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il4 interleukin 4 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of IL4 protein CTD PMID:29621558 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of IL6 protein
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of IL6 protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of IL6 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
CTD PMID:20056584, PMID:27565714, PMID:30503585, PMID:31268311 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of JUN protein
Sulfur Dioxide results in increased expression of JUN mRNA; Sulfur Dioxide results in increased expression of JUN protein
CTD PMID:19408242, PMID:19434695 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog increases expression ISO Sulfur Dioxide results in increased expression of KRAS mRNA; Sulfur Dioxide results in increased expression of KRAS protein CTD PMID:19434695 NCBI chr 6:145,216,699...145,250,420
Ensembl chr 6:145,216,699...145,250,239
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression
multiple interactions
EXP Sulfur Dioxide results in decreased expression of LHCGR mRNA
[Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of LHCGR mRNA
CTD PMID:30195209 NCBI chr17:88,716,384...88,792,059
Ensembl chr17:88,716,481...88,791,990
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] CTD PMID:30503585 NCBI chr 8:121,590,438...121,598,760
Ensembl chr 8:121,590,361...121,598,760
JBrowse link
G Mfn1 mitofusin 1 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN1 protein CTD PMID:27521637 NCBI chr 3:32,529,443...32,579,225
Ensembl chr 3:32,529,465...32,579,239
JBrowse link
G Mfn2 mitofusin 2 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein CTD PMID:27521637 NCBI chr 4:147,873,586...147,904,909
Ensembl chr 4:147,873,599...147,904,704
JBrowse link
G Mir1224 microRNA 1224 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR1224 mRNA CTD PMID:31268311 NCBI chr16:20,604,452...20,604,536
Ensembl chr16:20,604,452...20,604,536
JBrowse link
G Mir1249 microRNA 1249 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR1249 mRNA CTD PMID:30090456 NCBI chr15:84,951,526...84,951,623
Ensembl chr15:84,951,526...84,951,623
JBrowse link
G Mir125a microRNA 125a multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR125A mRNA CTD PMID:31268311 NCBI chr17:17,830,812...17,830,879
Ensembl chr17:17,830,812...17,830,879
JBrowse link
G Mir146b microRNA 146b multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR146B mRNA CTD PMID:31268311 NCBI chr19:46,342,762...46,342,870
Ensembl chr19:46,342,762...46,342,870
JBrowse link
G Mir155 microRNA 155 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR155 mRNA CTD PMID:31268311 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Mir185 microRNA 185 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR185 mRNA CTD PMID:30090456 NCBI chr16:18,327,401...18,327,465
Ensembl chr16:18,327,401...18,327,465
JBrowse link
G Mir186 microRNA 186 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR186 mRNA CTD PMID:31268311 NCBI chr 3:157,544,279...157,544,349
Ensembl chr 3:157,544,279...157,544,349
JBrowse link
G Mir1894 microRNA 1894 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR1894 mRNA CTD PMID:30090456 NCBI chr17:35,917,889...35,917,969
Ensembl chr17:35,917,889...35,917,969
JBrowse link
G Mir1927 microRNA 1927 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR1927 mRNA CTD PMID:30090456 NCBI chr 1:160,295,864...160,295,972
Ensembl chr 1:160,295,864...160,295,972
JBrowse link
G Mir205 microRNA 205 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR205 mRNA CTD PMID:30090456 NCBI chr 1:193,507,463...193,507,530
Ensembl chr 1:193,507,463...193,507,530
JBrowse link
G Mir210 microRNA 210 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR210 mRNA CTD PMID:31268311 NCBI chr 7:141,221,384...141,221,493
Ensembl chr 7:141,221,384...141,221,493
JBrowse link
G Mir21a microRNA 21a multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR21 mRNA CTD PMID:31268311 NCBI chr11:86,584,067...86,584,158
Ensembl chr11:86,584,067...86,584,158
JBrowse link
G Mir2861 microRNA 2861 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR2861 mRNA CTD PMID:31268311 NCBI chr 2:32,712,807...32,712,888
Ensembl chr 2:32,712,807...32,712,888
JBrowse link
G Mir3070b microRNA 3070b multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR3070B mRNA CTD PMID:30090456 NCBI chr12:109,588,592...109,588,680
Ensembl chr12:109,588,592...109,588,680
JBrowse link
G Mir3095 microRNA 3095 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR3095 mRNA CTD PMID:30090456 NCBI chr 4:58,441,012...58,441,098
Ensembl chr 4:58,441,012...58,441,098
JBrowse link
G Mir30a microRNA 30a multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR30A mRNA CTD PMID:31268311 NCBI chr 1:23,272,269...23,272,339
Ensembl chr 1:23,272,269...23,272,339
JBrowse link
G Mir30e microRNA 30e multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR30E mRNA CTD PMID:30090456 NCBI chr 4:120,772,606...120,772,697
Ensembl chr 4:120,772,606...120,772,697
JBrowse link
G Mir320 microRNA 320 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR320A mRNA CTD PMID:31268311 NCBI chr14:70,443,510...70,443,591
Ensembl chr14:70,443,510...70,443,591
JBrowse link
G Mir338 microRNA 338 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR338 mRNA CTD PMID:30090456 NCBI chr11:120,014,765...120,014,862
Ensembl chr11:120,014,765...120,014,862
JBrowse link
G Mir342 microRNA 342 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR342 mRNA CTD PMID:31268311 NCBI chr12:108,658,620...108,658,718
Ensembl chr12:108,658,620...108,658,718
JBrowse link
G Mir34b microRNA 34b multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR34B mRNA CTD PMID:30090456 NCBI chr 9:51,103,562...51,103,645
Ensembl chr 9:51,103,562...51,103,645
JBrowse link
G Mir374b microRNA 374b multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR374B mRNA CTD PMID:31268311 NCBI chr  X:103,573,060...103,573,154
Ensembl chr  X:103,573,060...103,573,154
JBrowse link
G Mir374c microRNA 374c multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR374C mRNA CTD PMID:30090456 NCBI chr  X:103,573,085...103,573,133
Ensembl chr  X:103,573,085...103,573,133
JBrowse link
G Mir375 microRNA 375 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR375 mRNA CTD PMID:30090456 NCBI chr 1:74,900,658...74,900,721
Ensembl chr 1:74,900,658...74,900,721
JBrowse link
G Mir425 microRNA 425 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR425 mRNA CTD PMID:30090456 NCBI chr 9:108,568,777...108,568,861
Ensembl chr 9:108,568,777...108,568,861
JBrowse link
G Mir434 microRNA 434 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of MIR434 mRNA CTD PMID:30090456 NCBI chr12:109,594,506...109,594,599
Ensembl chr12:109,594,506...109,594,599
JBrowse link
G Mir450b microRNA 450b multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR450B mRNA CTD PMID:30090456 NCBI chr  X:53,047,997...53,048,078
Ensembl chr  X:53,047,997...53,048,078
JBrowse link
G Mir483 microRNA 483 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR483 mRNA CTD PMID:31268311 NCBI chr 7:142,654,924...142,654,996
Ensembl chr 7:142,654,924...142,654,996
JBrowse link
G Mir500 microRNA 500 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR500 mRNA CTD PMID:30090456 NCBI chr  X:7,237,683...7,237,774
Ensembl chr  X:7,237,683...7,237,774
JBrowse link
G Mir503 microRNA 503 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR503 mRNA CTD PMID:31268311 NCBI chr  X:53,053,984...53,054,054
Ensembl chr  X:53,053,984...53,054,054
JBrowse link
G Mir504 microRNA 504 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR504 mRNA CTD PMID:30090456 NCBI chr  X:59,097,658...59,097,736
Ensembl chr  X:59,097,658...59,097,736
JBrowse link
G Mir615 microRNA 615 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR615 mRNA CTD PMID:31268311 NCBI chr15:103,014,910...103,015,001
Ensembl chr15:103,014,910...103,015,001
JBrowse link
G Mir674 microRNA 674 multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIR674 mRNA CTD PMID:30090456 NCBI chr 2:117,185,127...117,185,226
Ensembl chr 2:117,185,127...117,185,226
JBrowse link
G Mir93 microRNA 93 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR93 mRNA CTD PMID:31268311 NCBI chr 5:138,165,523...138,165,610
Ensembl chr 5:138,165,523...138,165,610
JBrowse link
G Mirlet7e microRNA let7e multiple interactions EXP
ISO
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MIRLET7E mRNA
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7E mRNA; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIRLET7E mRNA
CTD PMID:30090456, PMID:31268311 NCBI chr17:17,830,352...17,830,444
Ensembl chr17:17,830,352...17,830,444
JBrowse link
G Mirlet7i microRNA let7i multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIRLET7I mRNA CTD PMID:31268311 NCBI chr10:122,985,640...122,985,724
Ensembl chr10:122,985,640...122,985,724
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein] CTD PMID:30503585 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of ATP6 mRNA
Sulfur Dioxide results in decreased expression of ATP6 mRNA
CTD PMID:22677886, PMID:26980303 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607
JBrowse link
G mt-Atp8 ATP synthase 8, mitochondrial increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of ATP8 mRNA
Sulfur Dioxide results in decreased expression of ATP8 mRNA
CTD PMID:22677886, PMID:26980303 NCBI chr MT:7,766...7,969
Ensembl chr MT:7,766...7,969
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of COX1 mRNA
Sulfur Dioxide results in decreased expression of COX1 mRNA
CTD PMID:22677886, PMID:26980303 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G mt-Co2 cytochrome c oxidase II, mitochondrial decreases expression ISO Sulfur Dioxide results in decreased expression of COX2 mRNA CTD PMID:26980303 NCBI chr MT:7,013...7,696
Ensembl chr MT:7,013...7,696
JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial decreases expression ISO Sulfur Dioxide results in decreased expression of COX3 mRNA CTD PMID:26980303 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of MYC protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of MYC protein]
Sulfur Dioxide results in increased expression of MYC mRNA; Sulfur Dioxide results in increased expression of MYC protein
CTD PMID:19408242, PMID:19434695, PMID:20064080 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MYD88 mRNA CTD PMID:31268311 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of NOS2 mRNA; Sulfur Dioxide results in increased expression of NOS2 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
CTD PMID:20083630, PMID:30503585 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of NOS3 protein CTD PMID:30090456 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of NRF1 protein
Sulfur Dioxide results in decreased expression of NRF1 mRNA; Sulfur Dioxide results in decreased expression of NRF1 protein
CTD PMID:22677886, PMID:26980303 NCBI chr 6:30,047,985...30,153,458
Ensembl chr 6:30,047,988...30,153,458
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of OPA1 protein CTD PMID:27521637 NCBI chr16:29,579,281...29,663,127
Ensembl chr16:29,579,334...29,654,884
JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) affects expression ISO Sulfur Dioxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr17:43,567,994...43,612,202
Ensembl chr17:43,568,098...43,612,201
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
decreases expression
EXP glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha decreases expression ISO Sulfur Dioxide results in decreased expression of PPARGC1A mRNA; Sulfur Dioxide results in decreased expression of PPARGC1A protein CTD PMID:26980303 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Prg2 proteoglycan 2, bone marrow multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of PRG2 mRNA CTD PMID:29621558 NCBI chr 2:84,980,461...84,983,632
Ensembl chr 2:84,980,461...84,983,632
JBrowse link
G Ptger2 prostaglandin E receptor 2 (subtype EP2) increases expression
multiple interactions
ISO Sulfur Dioxide results in increased expression of PTGER2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER2 protein]
CTD PMID:21873648 NCBI chr14:44,988,111...45,003,820
Ensembl chr14:44,988,195...45,003,820
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) multiple interactions
increases expression
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGER4 protein] CTD PMID:21873648 NCBI chr15:5,233,399...5,244,187
Ensembl chr15:5,206,661...5,244,187
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
Sulfur Dioxide results in increased expression of PTGS2 mRNA; Sulfur Dioxide results in increased expression of PTGS2 protein
CTD PMID:20083630, PMID:21873648, PMID:26209559 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases expression
increases expression
ISO [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of RB1 protein; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in decreased expression of RB1 protein]
Sulfur Dioxide results in decreased expression of RB1 mRNA; Sulfur Dioxide results in decreased expression of RB1 protein
Sulfur Dioxide results in increased expression of RB1 protein
CTD PMID:19408242, PMID:19434695, PMID:20064080 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases phosphorylation
EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; CNR1 protein affects the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Shbg sex hormone binding globulin multiple interactions EXP [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of SHBG mRNA CTD PMID:30195209 NCBI chr11:69,610,282...69,618,026
Ensembl chr11:69,614,804...69,617,905
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
increases activity
ISO Sulfur Dioxide inhibits the reaction [Alloxan results in decreased activity of SOD1 protein]
Sulfur Dioxide results in increased activity of SOD1 protein
CTD PMID:10871429 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO [[Air Pollutants results in increased abundance of Sulfur Dioxide] which affects the methylation of SOD2 promoter] which affects the methylation of SOD2 promoter CTD PMID:31220783 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sostdc1 sclerostin domain containing 1 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of SOSTDC1 mRNA CTD PMID:29621558 NCBI chr12:36,314,169...36,318,452
Ensembl chr12:36,314,139...36,318,452
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Sulfur Dioxide co-treated with sodium arsenite] results in decreased expression of STAR mRNA CTD PMID:30195209 NCBI chr 8:25,808,474...25,815,982
Ensembl chr 8:25,806,555...25,815,982
JBrowse link
G Syp synaptophysin affects expression ISO Sulfur Dioxide affects the expression of SYP protein CTD PMID:25534910 NCBI chr  X:7,638,580...7,653,256
Ensembl chr  X:7,638,471...7,653,256
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression
decreases expression
ISO Sulfur Dioxide results in increased expression of TFAM mRNA
Sulfur Dioxide results in decreased expression of TFAM mRNA; Sulfur Dioxide results in decreased expression of TFAM protein
CTD PMID:22677886, PMID:26980303 NCBI chr10:71,225,468...71,238,328
Ensembl chr10:71,225,464...71,238,280
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Sulfur Dioxide results in increased expression of TGFB1 protein CTD PMID:27565714 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of TLR2 mRNA CTD PMID:31268311 NCBI chr 3:83,836,272...83,841,824
Ensembl chr 3:83,836,272...83,841,767
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased secretion of TNF protein; [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased secretion of TNF protein
CTD PMID:30503585, PMID:31268311 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 multiple interactions EXP [Air Pollutants results in increased abundance of [Carbon Monoxide co-treated with Nitrogen Oxides co-treated with Sulfur Dioxide]] which results in increased expression of TNFSF4 mRNA CTD PMID:29621558 NCBI chr 1:161,395,438...161,418,206
Ensembl chr 1:161,395,409...161,418,410
JBrowse link
G Trp53 transformation related protein 53 multiple interactions
increases expression
ISO
EXP
[Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 mRNA; [Sulfur Dioxide co-treated with Benzo(a)pyrene] results in increased expression of TP53 protein; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 mRNA]; Sulfur Dioxide promotes the reaction [Benzo(a)pyrene results in increased expression of TP53 protein]
[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of TRP53 protein
Sulfur Dioxide results in increased expression of TP53 mRNA; Sulfur Dioxide results in increased expression of TP53 protein
CTD PMID:19408242, PMID:19434695, PMID:20064080, PMID:27521637, PMID:30503585 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA] CTD PMID:30503585 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21475
    role 21452
      application 20933
        food additive 15793
          food bleaching agent 135
            sulfur dioxide 135
Path 2
Term Annotations click to browse term
  CHEBI ontology 21475
    role 21452
      biological role 21451
        physiological role 21424
          food component 21424
            food additive 15793
              food bleaching agent 135
                sulfur dioxide 135
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.